u 69593 has been researched along with fentanyl in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Cheng, J; McCorvy, JD; Tan, L; Yan, W | 1 |
| Avery, BA; Behnke, M; Chear, NJ; Hiranita, T; Kamble, SH; León, F; McCurdy, CR; McMahon, LR; Obeng, S; Patel, A; Ramanathan, S; Reeves, ME; Restrepo, LF; Sharma, A | 1 |
| Cometta-Morini, C; Kamal, J; Loew, G; Maguire, P; Tsai, N; Upton, C | 1 |
| Elde, RP; Lacey, CB; Miller, KE; Seybold, VS; Stevens, CW | 1 |
| Bennett, GJ; Kajander, KC; Seybold, VS; Stevens, CW | 1 |
| Bansinath, M; Puig, MM; Ramabadran, K; Turndorf, H | 2 |
| Blalock, JE; Carr, DJ; DeCosta, BR; Guarcello, V; Jacobson, AE; Kim, CH; Rice, KC | 1 |
| Frey, HH | 1 |
| Carter, BD; Clark, MJ; Medzihradsky, F | 1 |
| Ayesta, FJ; Emmett-Oglesby, MW; Herz, A; Shippenberg, TS | 1 |
| Archer, S; Bidlack, JM; Gatch, MB; Mello, NK; Negus, SS | 1 |
| Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK | 1 |
| Chen, XJ; Chi, ZQ; Dai, QY; Jin, WQ; Liu, ZH; Zhang, HP | 1 |
| Arvidsson, S; Bayati, A; Ekman, C; Larsson, M | 1 |
| Negus, SS; Schrode, K; Stevenson, GW | 1 |
| Bertini, S; Menozzi, A; Poli, E; Pozzoli, C; Serventi, P; Zullian, C | 1 |
| Bear, A; Brimson-Théberge, M; Frederick, Bd; Gillis, TE; Janes, AC; Kaufman, MJ; McWilliams, SB; Negus, SS; Renshaw, PF; Schrode, KM; Tong, Y | 1 |
| Kuo, A; Meutermans, W; Smith, MT; Wyse, BD | 1 |
| Abraham, AD; Burgeno, LM; Chavkin, C; Kuhar, JR; Land, BB; Ong, SE; Phillips, PEM; Reichard, KL; Schattauer, SS | 1 |
1 review(s) available for u 69593 and fentanyl
| Article | Year |
|---|---|
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.
Topics: Animals; Drug Discovery; Humans; Ligands; Receptors, G-Protein-Coupled; Signal Transduction; Structure-Activity Relationship | 2018 |
20 other study(ies) available for u 69593 and fentanyl
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Topics: Adrenergic Agents; Analgesics; Animals; Blood Proteins; CHO Cells; Cricetulus; Dopamine Agents; Guinea Pigs; Humans; Microsomes, Liver; Rats; Receptors, Adrenergic; Receptors, Opioid; Secologanin Tryptamine Alkaloids | 2020 |
Pharmacological profiles of fentanyl analogs at mu, delta and kappa opiate receptors.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1992 |
Biochemical characterization and regional quantification of mu, delta and kappa opioid binding sites in rat spinal cord.
Topics: Analgesics; Animals; Autoradiography; Benzeneacetamides; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Kinetics; Male; Pyrrolidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sufentanil; Tritium | 1991 |
Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy.
Topics: Analgesics; Animals; Autoradiography; Behavior, Animal; Benzeneacetamides; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Ligands; Male; Nervous System Diseases; Pain; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sensory Thresholds; Spinal Cord; Sufentanil | 1991 |
Effects of kappa- and mu-selective opiate agonists on colonic temperature in normoglycaemic and streptozotocin-treated hyperglycaemic mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Body Temperature; Colon; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fentanyl; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1990 |
Hyperglycemia does not modify the pupillary effects of mu and kappa opiate agonists in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Blood Glucose; Fentanyl; Half-Life; Hyperglycemia; Male; Mice; Morphine; Narcotics; Pupil; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Opioid receptors on cells of the immune system: evidence for delta- and kappa-classes.
Topics: Animals; Benzeneacetamides; Cell Line; Fentanyl; Indicators and Reagents; Macrophages; Mice; Mice, Inbred C57BL; Naltrexone; Pyrrolidines; Receptors, Opioid | 1989 |
Effect of mu- and kappa-opioid agonists on the electroconvulsive seizure threshold in mice and antagonism by naloxone and MR 2266.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Benzodiazepines; Benzomorphans; Electroshock; Fentanyl; Male; Mice; Morphinans; Morphine; Nalbuphine; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures | 1988 |
Selectivity of ligand binding to opioid receptors in brain membranes from the rat, monkey and guinea pig.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Brain Chemistry; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fentanyl; Guinea Pigs; Haplorhini; Pyrrolidines; Radioligand Assay; Rats; Receptors, Opioid; Sufentanil; Tritium | 1988 |
Tolerance and selective cross-tolerance to the motivational effects of opioids.
Topics: Analgesics; Animals; Benzeneacetamides; Choice Behavior; Conditioning, Operant; Dextroamphetamine; Drug Tolerance; Fentanyl; Male; Morphine; Motivation; Narcotics; Pyrrolidines; Rats; Rats, Inbred Strains | 1988 |
Effects of the structurally novel opioid 14 alpha, 14' beta-[dithiobis [(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) on schedule-controlled behavior and thermal nociception in rhesus monkeys.
Topics: Analgesics; Animals; Azocines; Behavior, Animal; Benzeneacetamides; Female; Fentanyl; Hot Temperature; Hydromorphone; Macaca mulatta; Male; Morphine; Narcotic Antagonists; Pain; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1996 |
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation | 1997 |
Opioid activity of C8813, a novel and potent opioid analgesic.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Cyclohexanols; Enkephalin, D-Penicillamine (2,5)-; Female; Fentanyl; Guinea Pigs; In Vitro Techniques; Male; Mice; Morphine; Pyrrolidines; Rabbits; Thiophenes | 2003 |
A model for chronic quantitative studies of colorectal sensitivity using balloon distension in conscious mice -- effects of opioid receptor agonists.
Topics: Abdominal Muscles; Analgesics, Opioid; Animals; Benzeneacetamides; Colon; Consciousness; Electromyography; Female; Fentanyl; Male; Mice; Models, Animal; Muscle Contraction; Nociceptors; Pain Measurement; Physical Stimulation; Pyrrolidines; Receptors, Opioid; Rectum; Sex Characteristics | 2003 |
Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Hot Temperature; Macaca mulatta; Male; Opioid-Related Disorders; Pain Measurement; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule; Self Administration | 2008 |
Inhibition of motility in isolated horse small intestine is mediated by κ but not µ opioid receptors.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Dose-Response Relationship, Drug; Fentanyl; Gastrointestinal Motility; Horses; Intestine, Small; Male; Morphine; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2012 |
A method for conducting functional MRI studies in alert nonhuman primates: initial results with opioid agonists in male cynomolgus monkeys.
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Benzeneacetamides; Caudate Nucleus; Conditioning, Psychological; Fentanyl; Hydrocortisone; Injections, Intravenous; Macaca fascicularis; Magnetic Resonance Imaging; Male; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Restraint, Physical; Stress, Physiological; Stress, Psychological; Wakefulness | 2013 |
In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Buprenorphine; Castor Oil; Constipation; Diarrhea; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Hot Temperature; Male; Morphine; Morphine Derivatives; Oxycodone; Pain; Pyrrolidines; Rats, Sprague-Dawley; Respiratory Insufficiency | 2015 |
Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; GTP-Binding Protein alpha Subunits, Gi-Go; JNK Mitogen-Activated Protein Kinases; Mice; Morphine; NADPH Oxidases; Peroxiredoxin VI; Phosphorylation; Pyrrolidines; Reactive Oxygen Species; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2017 |