Page last updated: 2024-08-26

u 69593 and bremazocine

u 69593 has been researched along with bremazocine in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (24.44)	18.7374
1990's	25 (55.56)	18.2507
2000's	8 (17.78)	29.6817
2010's	1 (2.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fujii, H; Hirono, S; Nagase, H; Yamaotsu, N	1
Horan, P; Porreca, F; Taylor, J; Yamamura, HI	1
Barnard, EA; Richardson, A; Simon, J	1
Barnard, EA; Demoliou-Mason, C; Richardson, A	1
de Costa, BR; Horan, P; Porreca, F; Rice, KC	1
Knapp, C; Unterwald, EM; Zukin, RS	1
Devlin, T; Shoemaker, WJ	1
Band, L; Bykov, V; de Costa, BR; Jacobson, AE; Pert, A; Rice, KC; Rothman, RB	1
Christensen, JD; Fjalland, B	1
Magnan, J; Tiberi, M	1
Dissanayake, VU; Hill, RG; Hughes, J; Hunter, JC	1
Baraldi, M; Zanoli, P	1
Band, L; Bowen, WD; Contreras, PC; de Costa, BR; Gray, NM; Jacobson, AE; Radesca, L; Rice, KC; Rothman, RB; Thurkauf, A	1
Bykov, V; de Costa, BR; Jacobson, AE; Rice, KC; Rothman, RB	1
Makimura, M; Murakoshi, Y	1
Bykov, V; De Costa, BR; France, CP; Jacobson, AE; Rice, KC; Rothman, RB; Woods, JH	1
Birchmore, B; Hughes, J; Hunter, JC; Woodruff, R	1
Rodriguez, FD; Traynor, JR; Wood, MS	1
Hill, RG; Hughes, J; Hunter, JC; Smith, JA	1
La Regina, A; Petrillo, P; Sbacchi, M; Tavani, A	1
Magnan, J; Pilapil, C; Quirion, R	1
Frey, HH	1
Cicero, TJ; Nock, B; O'Connor, LH; Rajpara, A	1
De Montis, GM; Devoto, P; Preti, A; Tagliamonte, A	1
Bidlack, JM; Joseph, DB; Lawrence, DM	1
Akil, H; Fox, CA; Mansour, A; Meng, F; Watson, SJ	1
Horan, PJ; Porreca, F	1
de Costa, BR; Haaseth, RC; Horan, PJ; Hruby, VJ; Porreca, F; Rice, K	1
Jin, WQ; Wong, TM; Zhang, WM	1
Nelson, WL; Palmer, RB; Upthagrove, AL	1
Caudle, RM; Dubner, R; Ho, J; Mannes, AJ	1
Fowler, CJ; Tiger, G	1
Mash, DC; Partilla, J; Rice, KC; Rothman, RB; Staley, JK	1
Caudle, RM; Iadarola, MJ; Mannes, AJ	1
Caudle, RM; Finegold, AA; Iadarola, MJ; Kenshalo, DR; Mannes, AJ; Tobias, MD	1
Boyer, JS; Craft, RM; Hanesworth, JM; Harding, JW; Kruzich, PJ	1
Holtzman, SG; Powell, KR	1
Craft, RM; Raub, DJ; Ulibarri, CM	1
De Vries, TJ; Schoffelmeer, AN; Vanderschuren, LJ; Wardeh, G	1
Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS	1
Collins, SL; D'Addario, C; Izenwasser, S	1
Collins, SL; D'Addario, C; Gerdes, RM; Izenwasser, S	1
Horie, S; Ishihara, S; Minowa, S; Murayama, T; Tsuchiya, S; Watanabe, K	1
Folk, JE; Linsenmayer, DC; Negus, SS; Rice, KC; Stevenson, GW	1
Bidlack, JM; Mello, NK; Negus, SS; Rusovici, DE	1

Other Studies

45 other study(ies) available for u 69593 and bremazocine

Article	Year
Identification of the three-dimensional pharmacophore of kappa-opioid receptor agonists. Bioorganic & medicinal chemistry, 2010, Jun-15, Volume: 18, Issue:12 Topics: Models, Chemical; Models, Molecular; Receptors, Opioid, kappa	2010
Extremely long-lasting antagonistic actions of nor-binaltorphimine (nor-BNI) in the mouse tail-flick test. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: Age Factors; Animals; Benzeneacetamides; Benzomorphans; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Time Factors	1992
Protection by opioid ligands against modification of the opioid receptor by a carbodiimide. Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Brain Chemistry; Carbodiimides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guanylyl Imidodiphosphate; Guinea Pigs; Pyrrolidines; Receptors, Opioid	1992
Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes. Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-01, Volume: 89, Issue:21 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Cell Membrane; Cerebellum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Etorphine; Female; GTP-Binding Proteins; Guinea Pigs; Humans; Kinetics; Ligands; Placenta; Pregnancy; Prosencephalon; Protein Binding; Pyrrolidines; Rats; Receptors, Opioid	1992
Differential antagonism of U69,593- and bremazocine-induced antinociception by (-)-UPHIT: evidence of kappa opioid receptor multiplicity in mice. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Cyclohexanes; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu	1991
Neuroanatomical localization of kappa 1 and kappa 2 opioid receptors in rat and guinea pig brain. Brain research, 1991, Oct-18, Volume: 562, Issue:1 Topics: Analgesics; Animals; Autoradiography; Benzeneacetamides; Benzomorphans; Brain; Ethylketocyclazocine; Guinea Pigs; Male; Organ Specificity; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Species Specificity; Tritium	1991
Characterization of kappa opioid binding using dynorphin A1-13 and U69,593 in the rat brain. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Culture Techniques; Dynorphins; Ligands; Male; Morphinans; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Tritium	1990
Probes for narcotic receptor mediated phenomena. 17. Synthesis and evaluation of a series of trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacet amide (U50,488) related isothiocyanate derivatives as opioid receptor affinity ligands. Journal of medicinal chemistry, 1990, Volume: 33, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Brain; Chemical Phenomena; Chemistry; Cyclohexanes; Guinea Pigs; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship; Thiocyanates	1990
Kappa-opioid receptor agonists differentially affect the release of neurohypophysial hormones. Pharmacology & toxicology, 1990, Volume: 66, Issue:3 Topics: Animals; Benzeneacetamides; Benzomorphans; Electric Stimulation; Female; In Vitro Techniques; Naloxone; Nerve Endings; Oxytocin; Pituitary Hormones, Posterior; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vasopressins	1990
Demonstration of the heterogeneity of the kappa-opioid receptors in guinea-pig cerebellum using selective and nonselective drugs. European journal of pharmacology, 1990, Jun-12, Volume: 188, Issue:6 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Cerebellum; Computers; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Membranes; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1990
Characterization of kappa-opioid receptors in the guinea-pig ileum. European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Naloxone; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes	1990
Evidence that bremazocine prevents urine retention induced by intraspinal cord injection of colchicine in rats. Journal of the autonomic nervous system, 1990, Volume: 30 Suppl Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Colchicine; Eledoisin; Hypertrophy; Injections, Spinal; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Spinal Cord; Urinary Bladder; Urination	1990
Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity sigma receptor ligands. Identification of a new class of highly potent and selective sigma receptor probes. Journal of medicinal chemistry, 1990, Volume: 33, Issue:11 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Cyclohexanes; Guinea Pigs; Molecular Structure; Pyrroles; Pyrrolidines; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Phencyclidine; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship	1990
Selective and enantiospecific acylation of kappa opioid receptors by (1S,2S)-trans-2-isothiocyanato-N-methyl-N-[2-(1-pyrrolidinyl) cyclohexy l] benzeneacetamide. Demonstration of kappa receptor heterogeneity. Journal of medicinal chemistry, 1989, Volume: 32, Issue:2 Topics: Acylation; Animals; Benzeneacetamides; Benzomorphans; Cyclohexanes; Guinea Pigs; In Vitro Techniques; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism	1989
Kappa-opioid agonists do not inhibit adenylate cyclase. Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclase Inhibitors; Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Methionine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Levorphanol; Morphine; Naloxone; Pentazocine; Pyrrolidines; Rana catesbeiana; Receptors, Opioid; Receptors, Opioid, kappa; Sodium Chloride	1989
Pharmacological activities of optically pure enantiomers of the kappa opioid agonist, U50,488, and its cis diastereomer: evidence for three kappa receptor subtypes. European journal of pharmacology, 1989, Aug-29, Volume: 167, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzodiazepines; Benzomorphans; Binding, Competitive; Brain Chemistry; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Female; Guinea Pigs; Macaca mulatta; Male; Membranes; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism	1989
Kappa opioid binding sites in the dog cerebral cortex and spinal cord. Neuroscience, 1989, Volume: 31, Issue:3 Topics: Animals; Benzeneacetamides; Benzomorphans; Cerebral Cortex; Dogs; Morphinans; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord	1989
Characterisation of kappa-opioid binding sites in rat and guinea-pig spinal cord. Neuropharmacology, 1989, Volume: 28, Issue:10 Topics: Animals; Benzeneacetamides; Benzomorphans; Captopril; Diprenorphine; Dynorphins; Guinea Pigs; In Vitro Techniques; Leucine; Ligands; Male; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord	1989
A kinetic analysis of kappa-opioid agonist binding using the selective radioligand [3H]U69593. Journal of neurochemistry, 1989, Volume: 53, Issue:1 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Guinea Pigs; Kinetics; Male; Morphinans; Pyrrolidines; Radioligand Assay; Tritium	1989
Interaction of U-69,593 with mu-, alpha- and kappa-opioid binding sites and its analgesic and intestinal effects in rats. Life sciences, 1988, Volume: 42, Issue:3 Topics: Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Gastrointestinal Motility; In Vitro Techniques; Male; Naloxone; Nociceptors; Pyrrolidines; Rats; Receptors, Opioid	1988
Localization of kappa opioid receptor binding sites in human forebrain using [3H]U69,593: comparison with [3H]bremazocine. Cellular and molecular neurobiology, 1987, Volume: 7, Issue:3 Topics: Autoradiography; Benzeneacetamides; Benzomorphans; Binding Sites; Brain; Humans; In Vitro Techniques; Morphinans; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Tissue Distribution	1987
Effect of mu- and kappa-opioid agonists on the electroconvulsive seizure threshold in mice and antagonism by naloxone and MR 2266. Pharmacology & toxicology, 1988, Volume: 62, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Benzodiazepines; Benzomorphans; Electroshock; Fentanyl; Male; Mice; Morphinans; Morphine; Nalbuphine; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures	1988
Autoradiography of [3H]U-69593 binding sites in rat brain: evidence for kappa opioid receptor subtypes. European journal of pharmacology, 1988, Sep-01, Volume: 154, Issue:1 Topics: Analgesics; Animals; Autoradiography; Benzeneacetamides; Benzomorphans; Binding Sites; Brain Chemistry; Cyclazocine; Ethylketocyclazocine; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Temperature	1988
Differential effect of mu, delta, and kappa opioid agonists on adenylate cyclase activity. Journal of neuroscience research, 1987, Volume: 17, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Corpus Striatum; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Male; Morphinans; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid	1987
Kappa opioid receptors expressed on three related thymoma cell lines. Differences in receptor-effector coupling. Biochemical pharmacology, 1995, Jan-06, Volume: 49, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Cell Membrane; GTP Phosphohydrolases; Kinetics; Mice; Pyrrolidines; Receptors, Opioid, kappa; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured	1995
Kappa 1 receptor mRNA distribution in the rat CNS: comparison to kappa receptor binding and prodynorphin mRNA. Molecular and cellular neurosciences, 1994, Volume: 5, Issue:2 Topics: Animals; Autoradiography; Benzeneacetamides; Benzomorphans; Brain; Enkephalins; In Situ Hybridization; Protein Precursors; Pyrrolidines; Rats; Receptors, Opioid, kappa; RNA, Messenger; Tissue Distribution	1994
Lack of cross-tolerance between U69,593 and bremazocine suggests kappa-opioid receptor multiplicity in mice. European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intraventricular; Male; Mice; Pyrrolidines; Receptors, Opioid, kappa	1993
Differential antagonism of bremazocine- and U69,593-induced antinociception by quadazocine: further functional evidence of opioid kappa receptor multiplicity in the mouse. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2 Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzodiazepines; Benzomorphans; Cyclohexanes; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Structure-Activity Relationship; Thiophenes	1993
Multiplicity of kappa opioid receptor binding in the rat cardiac sarcolemma. Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:7 Topics: Adenosine Triphosphatases; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Glucose-6-Phosphatase; Male; Myocardium; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sarcolemma; Tritium	1996
(E)- and (Z)-7-arylidenenaltrexones: synthesis and opioid receptor radioligand displacement assays. Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5 Topics: Animals; Benzeneacetamides; Benzomorphans; Benzylidene Compounds; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Conformation; Molecular Structure; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, delta; Spectroscopy, Fourier Transform Infrared	1997
Putative kappa-2 opioid agonists are antihyperalgesic in a rat model of inflammation. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Male; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa	1997
Comparison of the effects of a series of kappa-opioid receptor agonists upon sodium channel function in rat brain miniprisms. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1997, Volume: 117, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Brain; Disease Models, Animal; Inositol Phosphates; Naloxone; Pyrrolidines; Rats; Receptors, Opioid, kappa; Sodium Channels	1997
Kappa2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Amygdala; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Overdose; Female; Fentanyl; Gyrus Cinguli; Humans; Isothiocyanates; Kinetics; Male; Morphinans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa; Tissue Distribution; Up-Regulation	1997
GR89,696 is a kappa-2 opioid receptor agonist and a kappa-1 opioid receptor antagonist in the guinea pig hippocampus. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3 Topics: Animals; Benzeneacetamides; Benzomorphans; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Piperazines; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa	1997
Spinal kappa1 and kappa2 opioid binding sites in rats, guinea pigs, monkeys and humans. Neuroreport, 1998, Aug-03, Volume: 9, Issue:11 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Guinea Pigs; Humans; In Vitro Techniques; Macaca fascicularis; Macaca mulatta; Membranes; Pyrrolidines; Rats; Receptors, Opioid, kappa; Species Specificity; Spinal Cord	1998
Sex differences in discriminative stimulus and diuretic effects of the kappa opioid agonist U69,593 in the rat. Pharmacology, biochemistry, and behavior, 1998, Volume: 61, Issue:4 Topics: Animals; Benzeneacetamides; Benzomorphans; Brain; Discrimination Learning; Diuretics; Female; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement Schedule; Sex Characteristics	1998
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine. European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes	1999
Kappa opioid-induced diuresis in female vs. male rats. Pharmacology, biochemistry, and behavior, 2000, Jan-01, Volume: 65, Issue:1 Topics: Animals; Arginine Vasopressin; Benzeneacetamides; Benzomorphans; Butorphanol; Diuresis; Female; Male; Pentazocine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sex Factors	2000
Dissociable effects of the kappa-opioid receptor agonists bremazocine, U69593, and U50488H on locomotor activity and long-term behavioral sensitization induced by amphetamine and cocaine. Psychopharmacology, 2000, Volume: 150, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amphetamine; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Central Nervous System Stimulants; Cocaine; Male; Motor Activity; Psychomotor Agitation; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa	2000
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat. Life sciences, 2000, May-26, Volume: 67, Issue:1 Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin	2000
Effects of kappa-opioid receptor agonists on long-term cocaine use and dopamine neurotransmission. European journal of pharmacology, 2001, Aug-24, Volume: 426, Issue:1-2 Topics: Analgesics; Animals; Autoradiography; Benzazepines; Benzeneacetamides; Benzomorphans; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Opioid, kappa; Sulpiride; Synaptic Transmission; Time Factors; Tyrosine 3-Monooxygenase	2001
Kappa opioid agonists alter dopamine markers and cocaine-stimulated locomotor activity. Behavioural pharmacology, 2001, Volume: 12, Issue:4 Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Naltrexone; Nerve Net; Nerve Tissue Proteins; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa	2001
Involvement of glutamate and gamma-amino-butyric acid receptor systems on gastric acid secretion induced by activation of kappa-opioid receptors in the central nervous system in rats. British journal of pharmacology, 2003, Volume: 138, Issue:6 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Benzeneacetamides; Benzomorphans; Bicuculline; Brain; Dynorphins; gamma-Aminobutyric Acid; Gastric Acid; Injections, Intraventricular; Ketanserin; Male; Perfusion; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Serotonin; Stomach	2003
Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3 Topics: Analgesics, Opioid; Animals; Benzamides; Benzeneacetamides; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Pain; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule	2003
Kappa-opioid receptors are differentially labeled by arylacetamides and benzomorphans. European journal of pharmacology, 2004, Feb-06, Volume: 485, Issue:1-3 Topics: Acetamides; Animals; Benzeneacetamides; Benzomorphans; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Protein Binding; Pyrrolidines; Receptors, Opioid, kappa	2004