u 69593 has been researched along with 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burgess, JP; Carroll, FI; Dersch, CM; Herault, XM; Horel, RB; Mascarella, SW; Rothman, RB; Thomas, JB; Xu, H | 1 |
| Atkinson, RN; Carroll, FI; Dersch, CM; Herault, XM; Horel, RB; Mascarella, SW; Rothman, RB; Thomas, JB; Xu, H | 1 |
| Atkinson, RN; Burgess, JP; Carroll, FI; Dersch, CM; Flippen-Anderson, JL; George, CF; Herault, XM; Mascarella, SW; Rothman, RB; Thomas, JB; Xu, H | 1 |
| Ananthan, S; Bartlett, JL; Bilsky, EJ; Davis, P; Dersch, CM; Khare, NK; Porreca, F; Rothman, RB; Saini, SK; Seitz, LE | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Bourgeois, C; Christoph, T; Englberger, W; Galla, F; Galla, HJ; Hüwel, S; Kögel, B; Lehmkuhl, K; Schepmann, D; Soeberdt, M; Straßburger, W; Torres-Gómez, H; Werfel, E; Wünsch, B | 1 |
| Chadderdon, AM; Deschamps, JR; Hassan, SA; Jacobson, AE; Katz, JL; Kopajtic, TA; Lee, YS; Rice, KC; Traynor, JR; Truong, PM | 1 |
| Che, T; Kalinin, DV; Loser, K; Mykicki, N; Schepmann, D; Ständer, S; Tangherlini, G; Wünsch, B | 1 |
| Heyliger, SO; Lai, J; Ni, Q; Partilla, JS; Rice, KC; Romero, DV; Rothman, RB; Zheng, QX | 1 |
| Clot-Faybesse, O; Devaux, C; Guieu, R; Halimi, G; Legof, L; Rochat, H; Sampol, J | 1 |
| Balboni, G; Bryant, SD; Butterworth, J; Guerrini, R; Labarre, M; Lazarus, LH; Payza, K; Salvadori, S; Schmidhammer, H; St-Onge, S | 1 |
| Ananthan, S; Lu, YF; Rice, KC; Rothman, RB; Xu, H | 1 |
| Jones, RM; Linsenmayer, DC; Mello, NK; Negus, SS; Portoghese, PS | 1 |
| Folk, JE; Linsenmayer, DC; Negus, SS; Rice, KC; Stevenson, GW | 1 |
15 other study(ies) available for u 69593 and 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide
| Article | Year |
|---|---|
(+/-)-4-[(N-allyl-cis-3-methyl-4-piperidinyl)phenylamino]-N,N-diethylbenzamide displays selective binding for the delta opioid receptor.
Topics: Benzamides; Piperazines; Piperidines; Radioligand Assay; Receptors, Opioid, delta | 1999 |
Optically pure (-)-4-[(N-allyl-3-methyl-4-piperidinyl)phenyl-amino]-N,N-diethylbenzami de displays selective binding and full agonist activity for the delta opioid receptor.
Topics: Benzamides; Brain; Piperidines; Radioligand Assay; Receptors, Opioid, delta | 1999 |
Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides.
Topics: Animals; Benzamides; Brain; Crystallography, X-Ray; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2001 |
Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
Topics: Analgesics; Animals; Binding Sites; Brain; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred ICR; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Oxymorphone; Pyridines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted κ-opioid receptor agonists.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Blood-Brain Barrier; Brain; Endothelial Cells; Guinea Pigs; HEK293 Cells; Humans; Liver; Male; Mice; Models, Molecular; Pain Measurement; Permeability; Pyrrolidines; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship | 2014 |
Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study.
Topics: Carbon-13 Magnetic Resonance Spectroscopy; Computer Simulation; Crystallography, X-Ray; Models, Molecular; Molecular Dynamics Simulation; Morphinans; Protein Binding; Proton Magnetic Resonance Spectroscopy; Receptors, Opioid; Spectrometry, Mass, Electrospray Ionization | 2017 |
Development of Novel Quinoxaline-Based κ-Opioid Receptor Agonists for the Treatment of Neuroinflammation.
Topics: Animals; Antineoplastic Agents; Binding Sites; Encephalomyelitis, Autoimmune, Experimental; HEK293 Cells; Humans; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Docking Simulation; Protein Structure, Tertiary; Quinoxalines; Receptors, Opioid, kappa; Signal Transduction; Structure-Activity Relationship; Th1 Cells | 2019 |
Opioid peptide receptor studies. 12. Buprenorphine is a potent and selective mu/kappa antagonist in the [35S]-GTP-gamma-S functional binding assay.
Topics: Animals; Benzamides; Benzeneacetamides; Buprenorphine; Drug Evaluation, Preclinical; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Male; Mice; Narcotic Antagonists; Piperazines; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 1999 |
Modulation of adenosine concentration by opioid receptor agonists in rat striatum.
Topics: Adenosine; Animals; Benzamides; Benzeneacetamides; Binding, Competitive; Corpus Striatum; Female; Injections, Intraperitoneal; Oxymorphone; Phenethylamines; Piperazines; Purinergic P1 Receptor Agonists; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Purinergic P1; RNA, Messenger | 2000 |
Inverse agonism by Dmt-Tic analogues and HS 378, a naltrindole analogue.
Topics: Benzamides; Benzeneacetamides; Binding, Competitive; Cell Line; Cell Membrane; Dipeptides; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoquinolines; Naltrexone; Narcotic Antagonists; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Tetrahydroisoquinolines | 2000 |
SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Benzeneacetamides; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Iodine Radioisotopes; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Piperazines; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Tritium | 2001 |
Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Benzamides; Benzeneacetamides; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanidines; Macaca mulatta; Male; Morphinans; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Reinforcement Schedule; Time Factors | 2002 |
Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception.
Topics: Analgesics, Opioid; Animals; Benzamides; Benzeneacetamides; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Pain; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule | 2003 |