u 54494a has been researched along with 2-amino-5-phosphonovalerate in 2 studies
*2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. [MeSH]
*2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. [MeSH]
| Studies (u 54494a) | Trials (u 54494a) | Recent Studies (post-2010) (u 54494a) | Studies (2-amino-5-phosphonovalerate) | Trials (2-amino-5-phosphonovalerate) | Recent Studies (post-2010) (2-amino-5-phosphonovalerate) |
|---|---|---|---|---|---|
| 21 | 0 | 0 | 4,393 | 1 | 539 |
| Protein | Taxonomy | u 54494a (IC50) | 2-amino-5-phosphonovalerate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.29 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.29 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sage, GP; Sethy, VH | 1 |
| Leung, LS; Shen, B | 1 |
2 other study(ies) available for u 54494a and 2-amino-5-phosphonovalerate
| Article | Year |
|---|---|
Modulation of release of acetylcholine from the striatum by a proposed excitatory amino acid antagonist U-54494A: comparison with known antagonists, diazepam and phenytoin.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Anticonvulsants; Corpus Striatum; Diazepam; Dizocilpine Maleate; In Vitro Techniques; N-Methylaspartate; Phencyclidine; Phenytoin; Potassium; Pyrrolidines; Rats | 1992 |
Long-term potentiation in hippocampal CA1: effects of afterdischarges, NMDA antagonists, and anticonvulsants.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dizocilpine Maleate; Electrophysiology; Hippocampus; Male; N-Methylaspartate; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Synapses | 1993 |