Compounds > u 0521
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u 0521 and levodopa

u 0521 has been researched along with levodopa in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Comi, R; Fahn, S; Prasad, AL; Snider, SR1
Kaakkola, S; Männistö, PT; Nuutila, J1
Fahn, S; Reches, A1
Fahn, S; Jiang, D; Reches, A2

Other Studies

5 other study(ies) available for u 0521 and levodopa

ArticleYear
Effect of a catechol-O-methyl transferase inhibitor, U-0521, with levodopa administration.
    Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7

    Topics: Animals; Behavior, Animal; Brain; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Methyldopa; Propiophenones; Rats; Time Factors

1979
Potentiation of central effects of L-dopa by an inhibitor of catechol-O-methyltransferase.
    Journal of neural transmission, 1987, Volume: 70, Issue:3-4

    Topics: Animals; Behavior, Animal; Catalepsy; Catechol O-Methyltransferase Inhibitors; Central Nervous System; Haloperidol; Levodopa; Male; Motor Activity; Phenethylamines; Propiophenones; Rats; Selegiline; Specific Pathogen-Free Organisms

1987
Catechol-O-methyltransferase and Parkinson's disease.
    Advances in neurology, 1984, Volume: 40

    Topics: Animals; Brain; Catechol O-Methyltransferase; Corpus Striatum; Levodopa; Male; Methyldopa; Parkinson Disease; Propiophenones; Rats; Rats, Inbred Strains

1984
Catechol-O-methyltransferase inhibition by U-0521 increases striatal utilization of levodopa.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:1

    Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Corpus Striatum; Dose-Response Relationship, Drug; Levodopa; Male; Methyldopa; Propiophenones; Rats; Rats, Inbred Strains; Time Factors

1982
Effect of 3',4'-dihydroxy-2-methyl-propriophenone (U-0521) on catechol-O-methyltransferase activity and on DOPA accumulation in rat red blood cells and corpus striatum.
    Biochemical pharmacology, 1982, Nov-01, Volume: 31, Issue:21

    Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dose-Response Relationship, Drug; Erythrocytes; Levodopa; Male; Propiophenones; Rats; Rats, Inbred Strains

1982