u 0521 has been researched along with isoproterenol in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Birnbaumer, L; Hoppe, BH; Kaumann, AJ; Wittmann, R | 1 |
| Bryan, LJ; O'Donnell, SR | 1 |
| Borda, ES; Gimeno, AL; Gimeno, MF; Sterin-Borda, L | 1 |
| Azevedo, I; Osswald, W | 1 |
| Azevedo, I; Cardoso, W; Guimarães, S; Oliveira, MC | 1 |
| Guimarães, S; Proença, J | 1 |
| Guimarães, S; Paiva, MQ; Proença, J | 2 |
| Armstrong, DT; Calaresu, FR; Morley, P | 1 |
| Guimarães, S; Moura, D; Paiva, MQ; Proença, J | 1 |
| Barone, S; Bennett, L; Head, RJ; Panek, D; Stitzel, RE | 1 |
| Douglas, JS; Duncan, PG | 1 |
| Guimarães, S; Paiva, MQ | 2 |
| Barone, S; Head, RJ; Stitzel, RE | 1 |
| Bryan, LJ; Fleig, H; Trendelenburg, U | 1 |
| Cornish, EJ; Goldie, RG | 1 |
| Azevedo, I; Branco, D; Osswald, W; Sarmento, A | 1 |
| Garland, LG; Marrion, NV; Martin, GR | 1 |
| De La Lande, IS; Head, RJ; Irvine, RJ; Johnson, SM | 1 |
20 other study(ies) available for u 0521 and isoproterenol
| Article | Year |
|---|---|
Activation of myocardial beta-adrenoceptors by the nitrogen-free low affinity ligand 3',4'-dihydroxy-alpha-methylpropiophenone (U-0521).
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cats; Cell Membrane; Corticosterone; Cyclic AMP; Drug Interactions; Female; Heart; Heart Rate; Hydrocortisone; In Vitro Techniques; Isoproterenol; Ligands; Male; Myocardium; Nitrogen; Propanolamines; Propiophenones; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stimulation, Chemical; Structure-Activity Relationship | 1977 |
Comparison of the effects of tropolone, beta-thujaplicin and U-0521 on the extraneuronal accumulation of isoprenaline in guinea-pig trachealis smooth muscle cells. A quantitative fluorescence histochemical study.
Topics: Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cycloheptanes; Female; Guinea Pigs; Histocytochemistry; In Vitro Techniques; Isoproterenol; Kinetics; Monoterpenes; Muscle, Smooth; Propiophenones; Trachea; Tropolone | 1979 |
A positive influence of frequency on the inotrophic response of isolated rat atria to certain adrenergic amines. Effects of cocaine and U-0521 (3',4'-dihydroxy-2-methyl propiophenone.
Topics: Animals; Calcium Chloride; Cocaine; Drug Interactions; Electric Stimulation; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Norepinephrine; Phenylephrine; Propiophenones; Rats; Sympathomimetics | 1977 |
Uptake, distribution and metabolism of isoprenaline in the dog saphenous vein.
Topics: Animals; Autoradiography; Biological Transport; Desoxycorticosterone; Dogs; Isoproterenol; Methylation; Microscopy, Electron; Muscle, Smooth; Propiophenones; Saphenous Vein | 1976 |
Relation between the amount of smooth muscle of venous tissue and the degree of supersensitivity to isoprenaline caused by inhibition of catechol-O-methyl transferase.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Desoxycorticosterone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Histological Techniques; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Oxytetracycline; Propiophenones; Saphenous Vein | 1975 |
Influence of inhibition of extraneuronal uptake and of O-methylation on the hyperglycaemia caused by sympathomimetic amines in depancreatized rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Epinephrine; Hydrocortisone; Hyperglycemia; Isoproterenol; Methylation; Pancreatectomy; Propiophenones; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1992 |
Supersensitivity to catecholamines after inhibition of extraneuronal uptake (uptake2) or O-methylation.
Topics: Animals; Catecholamines; Female; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Isoproterenol; Methylation; Propiophenones; Rats; Receptors, Adrenergic, beta; Trachea; Uterine Contraction | 1990 |
Catecholamines inhibit steroidogenesis by cultured porcine thecal cells.
Topics: Androstenedione; Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Female; Isoproterenol; Luteinizing Hormone; Metoprolol; Propiophenones; Swine; Theca Cells | 1990 |
The saturability of a site of loss and the degree of supersensitivity to agonists which are substrates of this site of loss.
Topics: Acetylcholine; Animals; Atropine; Binding Sites; Catechol O-Methyltransferase Inhibitors; Cocaine; Dogs; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Neurons; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phentolamine; Propiophenones; Propranolol; Saphenous Vein; Synaptic Transmission; Trachea; Yohimbine | 1985 |
The guinea-pig trachea O-methylating system is more effective in modulating beta 2- than beta 1-adrenoceptor-mediated responses to isoprenaline.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Methylation; Muscle Relaxation; Propanolamines; Propiophenones; Receptors, Adrenergic, beta; Trachea | 1988 |
The influence of oestrogen and oestrogen metabolites on the sensitivity of the isolated rabbit aorta to catecholamines.
Topics: 2-Methoxyestradiol; Animals; Aorta, Thoracic; Catechol O-Methyltransferase Inhibitors; Catecholamines; Epinephrine; Estradiol; Estrogens; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Propiophenones; Rabbits | 1987 |
Age-related changes in guinea pig respiratory tissues: considerations for assessment of bronchodilators.
Topics: Age Factors; Albuterol; Animals; Bronchi; Bronchodilator Agents; Carbachol; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Hydrocortisone; In Vitro Techniques; Isoproterenol; Muscle Contraction; Propiophenones; Trachea | 1985 |
The oil immersion technique for studying the disposition of drugs inducing relaxation; influence of U-0521 and hydrocortisone on the disposition of isoprenaline.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Hydrocortisone; In Vitro Techniques; Isoproterenol; Methylation; Muscle Contraction; Muscle Relaxation; Propiophenones; Time Factors | 1980 |
The kinetic characteristics of the extraneuronal Q-methylating system of the dog saphenous vein and the supersensitivity to catecholamines caused by its inhibition.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Dogs; Epinephrine; In Vitro Techniques; Isoproterenol; Kinetics; Methylation; Neurons; Norepinephrine; Phentolamine; Phenylephrine; Propiophenones; Saphenous Vein; Stereoisomerism; Tritium | 1984 |
Non-radiochemical procedure for the measurement of O-methylation of the stereoisomers of isoprenaline.
Topics: Animals; Aorta, Thoracic; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Electrochemistry; In Vitro Techniques; Isoproterenol; Male; Methylation; Propiophenones; Rabbits; Stereoisomerism | 1984 |
A comparative study of the properties of the catechol-O-methyltransferase inhibitors, U-0521 and tropolone acetamide, in rat perfused heart.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Cycloheptanes; Drug Interactions; Isoproterenol; Kinetics; Male; Models, Biological; Myocardium; Perfusion; Propiophenones; Rats; Rats, Inbred Strains; Tropolone | 1983 |
Metabolism of [3H]-(+/-)-isoprenaline by isolated atria and coronary arteries of the kitten.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Cats; Coronary Vessels; Female; Hydrocortisone; In Vitro Techniques; Isoproterenol; Male; Myocardium; Propiophenones; Tritium | 1980 |
The fate of isoprenaline in the isolated rabbit aorta. Radiochemical and morphologic observations.
Topics: Animals; Aorta; Autoradiography; Cocaine; Desoxycorticosterone; In Vitro Techniques; Isoproterenol; Methylation; Propiophenones; Rabbits | 1981 |
The extraneuronal O-methylation of 3H-(+)isoprenaline by guinea-pig tracheal rings in vitro.
Topics: Animals; Bethanechol Compounds; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Methylation; Muscle, Smooth; Propiophenones; Trachea | 1981 |
Uptake and O-methylation of isoprenaline in the rabbit ear artery.
Topics: Animals; Arteries; Catechol O-Methyltransferase Inhibitors; Denervation; Desoxycorticosterone; Ear; Isoproterenol; Kinetics; Methylation; Propiophenones; Rabbits; Sympathetic Nervous System | 1980 |