tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine has been researched along with naloxone in 8 studies
| Studies (tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine) | Trials (tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine) | Recent Studies (post-2010) (tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 25 | 0 | 0 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickenson, AH; Stanfa, LC; Sullivan, AF | 1 |
| Dickenson, AH; Kalso, EA; McQuay, HJ; Sullivan, AF | 1 |
| Calenco-Choukroun, G; Daugé, V; Féger, J; Gacel, G; Roques, BP | 1 |
| Drukarch, B; Mulder, AH; Ruuls, SR; Schoffelmeer, AN; Van Vliet, BJ | 1 |
| Hogenboom, F; Mulder, AH; Schoffelmeer, AN; Warden, G | 1 |
| Dickenson, A; Haley, J; Ketchum, S | 1 |
| Feger, J; Maldonado, R; Roques, BP; Waksman, G | 1 |
| Feger, J; Fournié-Zaluski, MC; Maldonado, R; Roques, BP | 1 |
8 other study(ies) available for tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine and naloxone
| Article | Year |
|---|---|
Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation.
Topics: Animals; Benzeneacetamides; Carrageenan; Dose-Response Relationship, Drug; Injections, Spinal; Male; Morphine; Myelitis; Naloxone; Neurons; Oligopeptides; Palliative Care; Pyrrolidines; Rats; Rats, Sprague-Dawley | 1992 |
Spinal antinociception by Tyr-D-Ser(otbu)-Gly-Phe-Leu-Thr, a selective delta-opioid receptor agonist.
Topics: Amino Acid Sequence; Analgesics; Animals; Dose-Response Relationship, Drug; Indoles; Injections, Spinal; Male; Molecular Sequence Data; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1992 |
Opioid delta agonists and endogenous enkephalins induce different emotional reactivity than mu agonists after injection in the rat ventral tegmental area.
Topics: Animals; Anxiety; Emotions; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Exploratory Behavior; Indoles; Injections; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali | 1991 |
Beta-adrenoceptor-sensitive adenylate cyclase is inhibited by activation of mu-opioid receptors in rat striatal neurons.
Topics: Adenylyl Cyclase Inhibitors; Analgesics; Animals; Astrocytes; Cells, Cultured; Corpus Striatum; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Isoproterenol; Male; Naloxone; Neuroglia; Neurons; Norepinephrine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Beta-endorphin: a highly selective endogenous opioid agonist for presynaptic mu opioid receptors.
Topics: Animals; beta-Endorphin; Brain; Culture Techniques; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Neurotransmitter Agents; Norepinephrine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Peripheral kappa-opioid modulation of the formalin response: an electrophysiological study in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Electric Stimulation; Electrophysiology; Evans Blue; Formaldehyde; Male; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Nociceptors; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1990 |
Naloxone-induced withdrawal syndrome after administration of selective opioid agonists or after activation of the endogenous enkephalinergic system.
Topics: Animals; Behavior, Animal; Body Temperature; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxamic Acids; Naloxone; Narcotics; Oligopeptides; Phenylalanine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Weight Loss | 1990 |
Differences in physical dependence induced by selective mu or delta opioid agonists and by endogenous enkephalins protected by peptidase inhibitors.
Topics: Animals; Cerebral Ventricles; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxamic Acids; Injections, Intraventricular; Male; Naloxone; Neprilysin; Oligopeptides; Phenylalanine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reference Values; Substance Withdrawal Syndrome; Substance-Related Disorders | 1990 |