tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl) has been researched along with naltrexone in 8 studies
| Studies (tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl)) | Trials (tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl)) | Recent Studies (post-2010) (tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl)) | Studies (naltrexone) | Trials (naltrexone) | Recent Studies (post-2010) (naltrexone) |
|---|---|---|---|---|---|
| 15 | 0 | 0 | 8,745 | 1,228 | 2,642 |
| Protein | Taxonomy | tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl) (IC50) | naltrexone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 1 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0051 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0063 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.006 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.006 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0319 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0093 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0377 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0076 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calenco-Choukroun, G; Daugé, V; Féger, J; Gacel, G; Roques, BP | 1 |
| Baamonde, A; Daugé, V; Gacel, G; Roques, BP | 1 |
| Noble, F; Roques, BP; Smadja, C | 1 |
| Desmeules, JA; Gacel, G; Guilbaud, G; Kayser, V; Roques, BP | 1 |
| Desmeules, JA; Guilbaud, G; Kayser, V | 1 |
| Gilbert-Rahola, J; Maldonado, R; Micó, JA; Roques, BP; Smadja, C; Tejedor-Real, P | 1 |
| Borsodi, A; Garzon, J; Hutcheson, DM; Maldonado, R; Rodriguez-Diaz, M; Roques, BP; Sánchez-Blazquez, P; Schmidhammer, H | 1 |
| Kieffer, BL; Maldonado, R; Matthes, HW; Melchiorri, P; Negri, L; Severini, C | 1 |
8 other study(ies) available for tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl) and naltrexone
| Article | Year |
|---|---|
Opioid delta agonists and endogenous enkephalins induce different emotional reactivity than mu agonists after injection in the rat ventral tegmental area.
Topics: Animals; Anxiety; Emotions; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Exploratory Behavior; Indoles; Injections; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali | 1991 |
Systemic administration of (Tyr-D-Ser(O-tert-butyl)-Gly-Phe-Leu-Thr(O-tert-butyl), a highly selective delta opioid agonist, induces mu receptor-mediated analgesia in mice.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Indoles; Injections, Intravenous; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.
Topics: Amino Acid Sequence; Analgesia; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Naloxone; Naltrexone; Oligopeptides; Peptide Fragments; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide | 1994 |
The highly selective delta agonist BUBU induces an analgesic effect in normal and arthritic rat and this action is not affected by repeated administration of low doses of morphine.
Topics: Analgesics; Animals; Arthritis, Experimental; Drug Administration Schedule; Drug Interactions; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reference Values; Vocalization, Animal | 1993 |
Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain.
Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Disease Models, Animal; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vocalization, Animal | 1993 |
Involvement of delta-opioid receptors in the effects induced by endogenous enkephalins on learned helplessness model.
Topics: Analgesics; Animals; Behavior, Animal; Disulfides; Drug Interactions; Enkephalins; Helplessness, Learned; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Phenylalanine; Rats; Rats, Wistar; Receptors, Opioid, delta | 1998 |
Use of selective antagonists and antisense oligonucleotides to evaluate the mechanisms of BUBU antinociception.
Topics: Analgesics; Animals; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Oligonucleotides, Antisense; Oligopeptides; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu | 1999 |
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 2001 |