tyrosyl-prolyl-tryptophyl-glycinamide has been researched along with enkephalin, leucine in 4 studies
| Studies (tyrosyl-prolyl-tryptophyl-glycinamide) | Trials (tyrosyl-prolyl-tryptophyl-glycinamide) | Recent Studies (post-2010) (tyrosyl-prolyl-tryptophyl-glycinamide) | Studies (enkephalin, leucine) | Trials (enkephalin, leucine) | Recent Studies (post-2010) (enkephalin, leucine) |
|---|---|---|---|---|---|
| 25 | 0 | 0 | 11,524 | 80 | 754 |
| Protein | Taxonomy | tyrosyl-prolyl-tryptophyl-glycinamide (IC50) | enkephalin, leucine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0142 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0417 | |
| Mu-type opioid receptor | Homo sapiens (human) | 9.5 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0308 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.246 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, SL; Hackler, L; Kastin, AJ; Zadina, JE | 1 |
| Ge, LJ; Hackler, L; Kastin, AJ; Zadina, JE | 2 |
| Harrison, LM; Kastin, AJ; Zadina, JE | 1 |
4 other study(ies) available for tyrosyl-prolyl-tryptophyl-glycinamide and enkephalin, leucine
| Article | Year |
|---|---|
Cyclic analogues of Tyr-W-MIF-1 with prolonged analgesic activity and potency comparable to DAMGO and morphine.
Topics: Analgesia; Analgesics; Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Male; Morphine; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Pain; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Mu, delta, and kappa opiate receptor binding of Tyr-MIF-1 and of Tyr-W-MIF-1, its active fragments, and two potent analogs.
Topics: Amino Acid Sequence; Animals; Brain; Cerebellum; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Molecular Sequence Data; MSH Release-Inhibiting Hormone; Peptide Fragments; Peptides, Cyclic; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Synaptic Membranes | 1994 |
A potent and selective endogenous agonist for the mu-opiate receptor.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Brain Chemistry; Cattle; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Mice; MSH Release-Inhibiting Hormone; Oligopeptides; Radioimmunoassay; Receptors, Opioid, mu | 1997 |
Differential effects of endomorphin-1, endomorphin-2, and Tyr-W-MIF-1 on activation of G-proteins in SH-SY5Y human neuroblastoma membranes.
Topics: Cell Membrane; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Neuroblastoma; Oligopeptides; Receptors, Opioid; Tumor Cells, Cultured | 1998 |