tyrosyl-prolyl-leucyl-glycinamide has been researched along with morphine in 15 studies
| Studies (tyrosyl-prolyl-leucyl-glycinamide) | Trials (tyrosyl-prolyl-leucyl-glycinamide) | Recent Studies (post-2010) (tyrosyl-prolyl-leucyl-glycinamide) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 109 | 0 | 0 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | tyrosyl-prolyl-leucyl-glycinamide (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kastin, AJ; Kersh, D; Wyatt, A; Zadina, JE | 1 |
| Kastin, AJ; Krowicki, ZK | 1 |
| Bungart, KJ; Ge, LJ; Gulden, H; Kastin, AJ; Zadina, JE | 1 |
| Chi, DS; Kastin, AJ; Strimas, JH | 1 |
| Coy, DH; Fischman, AJ; Kastin, AJ; Stephens, E; Zadina, JE | 1 |
| Banks, WA; Kastin, AJ; Nager, BJ | 1 |
| Abel, DA; Coy, DH; Ehrensing, RH; Graf, MV; Kastin, AJ | 1 |
| Ehrensing, RH; Fischman, AJ; Kastin, AJ; Stephens, E | 1 |
| Banks, WA; Harrison, LM; Kastin, AJ; Zadina, JE | 1 |
| Banks, WA; Kastin, AJ | 1 |
| Chang, SL; Ge, LJ; Kastin, AJ; Zadina, JE | 1 |
| Benson, TM; Corriere, LS; Handunge, BP; Kastin, AJ; Lake, JR; Leyva, JE; Malin, DR; Rogillio, RB; Zadina, JE | 1 |
| Kenigs, V; Nores, WL; Olson, GA; Olson, RD; Thomas, J | 1 |
| Fukunaga, H; Kaneto, H; Takahashi, M; Yoshikawa, M | 1 |
| Bocheva, A; Dzambazova-Maximova, E | 1 |
15 other study(ies) available for tyrosyl-prolyl-leucyl-glycinamide and morphine
| Article | Year |
|---|---|
Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Hemoglobins; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1992 |
Effects of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) on GH, LH, prolactin, FSH, and TSH secretion in rats with and without morphine.
Topics: Amino Acid Sequence; Animals; Drug Interactions; Female; Follicle Stimulating Hormone; Growth Hormone; Kinetics; Luteinizing Hormone; Male; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone; Ovariectomy; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin | 1991 |
Chronic, but not acute, administration of morphine alters antiopiate (Tyr-MIF-1) binding sites in rat brain.
Topics: Animals; Brain; Male; Morphine; MSH Release-Inhibiting Hormone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
In vitro studies of Tyr-MIF-1 with human lymphocytes.
Topics: Antigens, CD; Cell Division; Concanavalin A; Humans; In Vitro Techniques; Lymphocytes; Morphine; MSH Release-Inhibiting Hormone; Naloxone | 1989 |
Tyr-MIF-1, identified in brain tissue, and its analogs are active in two models of antinociception.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross Reactions; Male; Mice; Morphine; MSH Release-Inhibiting Hormone; Pain; Reaction Time; Structure-Activity Relationship | 1985 |
Analgesia and the blood-brain barrier transport system for Tyr-MIF-1/enkephalins: evidence for a dissociation.
Topics: Animals; Blood-Brain Barrier; Enkephalins; Food Deprivation; Male; Mice; Mice, Inbred ICR; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Pain; Restraint, Physical; Stereoisomerism; Stress, Physiological; Time Factors; Water Deprivation | 1988 |
Tyr-MIF-1 and MIF-1 are active in the water wheel test for antidepressant drugs.
Topics: Animals; Antidepressive Agents; Delta Sleep-Inducing Peptide; Drug Interactions; Mice; Morphine; Motor Activity; MSH Release-Inhibiting Hormone; Oligopeptides | 1984 |
Tyr-MIF-1 acts as an opiate antagonist in the tail-flick test.
Topics: Animals; Hot Temperature; Male; Mice; Mice, Inbred ICR; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Pain | 1984 |
Effects of neonatal treatment with Tyr-MIF-1, morphiceptin, and morphine on development, tail flick, and blood-brain barrier transport.
Topics: Analgesics; Animals; Animals, Newborn; Behavior, Animal; Blood-Brain Barrier; Body Weight; Endorphins; Eye; Female; Growth; Iodine Radioisotopes; Morphine; MSH Release-Inhibiting Hormone; Nociceptors; Pain Measurement; Pregnancy; Rats | 1993 |
Opposite direction of transport across the blood-brain barrier for Tyr-MIF-1 and MIF-1: comparison with morphine.
Topics: Amino Acid Sequence; Animals; Blood-Brain Barrier; Injections, Intravenous; Injections, Intraventricular; Mice; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone | 1994 |
Mu opiate receptor down-regulation by morphine and up-regulation by naloxone in SH-SY5Y human neuroblastoma cells.
Topics: Amino Acid Sequence; Cell Differentiation; Dose-Response Relationship, Drug; Down-Regulation; Humans; Kinetics; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Neuroblastoma; Pentazocine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Opioid, mu; Temperature; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1993 |
Tyr-MIF-1 precipitates abstinence syndrome in morphine-dependent rats.
Topics: Animals; Humans; Infant, Newborn; Male; Morphine; Morphine Dependence; MSH Release-Inhibiting Hormone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1993 |
Picrotoxin-induced seizures modified by morphine and opiate antagonists.
Topics: Animals; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Male; Morphine; Motor Activity; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Picrotoxin; Rats; Seizures | 1993 |
Effects of Tyr-MIF-1 on stress-induced analgesia and the blockade of development of morphine tolerance by stress in mice.
Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Behavior, Animal; Drug Interactions; Drug Tolerance; Male; Mice; Morphine; MSH Release-Inhibiting Hormone; Pain; Pain Measurement; Stress, Physiological; Swimming | 1999 |
Antiopioid properties of the TYR-MIF-1 family.
Topics: Animals; Hindlimb; Immobilization; Morphine; MSH Release-Inhibiting Hormone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Wistar; Tail; Time Factors | 2004 |