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tyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide and morphine

tyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide has been researched along with morphine in 5 studies

Compound Research Comparison

Studies
(tyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide)
Trials
(tyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide)
Recent Studies (post-2010)
(tyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
180044,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomytyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dupouy, V; Zajac, JM2
Desprat, C; Zajac, JM1
Francés, B; Gelot, A; Latapie, JP; Roussin, A; Zajac, JM1
Coudoré-Civiale, MA; Courteix, C; Eschalier, A; Fialip, J; Privat, AM; Zajac, JM1

Other Studies

5 other study(ies) available for tyrosyl-leucyl-n-methylphenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide and morphine

ArticleYear
Effects of neuropeptide FF analogs on morphine analgesia in the nucleus raphe dorsalis.
    Regulatory peptides, 1995, Nov-10, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Molecular Sequence Data; Morphine; Neuropeptides; Oligopeptides; Pain Measurement; Pain Threshold; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid

1995
Neuropeptide FF receptors control morphine-induced analgesia in the parafascicular nucleus and the dorsal raphe nucleus.
    European journal of pharmacology, 1997, Jul-09, Volume: 330, Issue:2-3

    Topics: 5,6-Dihydroxytryptamine; Analgesics, Opioid; Animals; Drug Interactions; Fenclonine; Male; Microinjections; Morphine; Narcotic Antagonists; Oligopeptides; Pain Measurement; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Serotonin; Serotonin Agents; Thalamic Nuclei

1997
Differential modulation of mu- and delta-opioid antinociception by neuropeptide FF receptors in young mice.
    Neuropeptides, 1997, Volume: 31, Issue:1

    Topics: Age Factors; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Neuropeptides; Nociceptors; Oligopeptides; Receptors, Neuropeptide; Receptors, Opioid, delta; Receptors, Opioid, mu

1997
Anti-opioid efficacy of neuropeptide FF in morphine-tolerant mice.
    Brain research, 1998, Oct-19, Volume: 808, Issue:2

    Topics: Animals; Antibodies; Drug Tolerance; Hot Temperature; Male; Mice; Morphine; Morphine Dependence; Narcotic Antagonists; Narcotics; Neuropeptides; Nociceptors; Olfactory Bulb; Oligopeptides; Pain; Pain Measurement; Receptors, Neuropeptide; Reflex; Spinal Cord

1998
Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine-induced analgesia in mononeuropathic and diabetic rats.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hyperalgesia; Injections, Spinal; Male; Morphine; Naltrexone; Narcotic Antagonists; Nervous System Diseases; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Somatostatin; Time Factors; Vocalization, Animal

1999