tyrosyl-arginyl-phenylalanyl-lysinamide has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 17 studies
| Studies (tyrosyl-arginyl-phenylalanyl-lysinamide) | Trials (tyrosyl-arginyl-phenylalanyl-lysinamide) | Recent Studies (post-2010) (tyrosyl-arginyl-phenylalanyl-lysinamide) | Studies (enkephalin, ala(2)-mephe(4)-gly(5)-) | Trials (enkephalin, ala(2)-mephe(4)-gly(5)-) | Recent Studies (post-2010) (enkephalin, ala(2)-mephe(4)-gly(5)-) |
|---|---|---|---|---|---|
| 74 | 0 | 17 | 151 | 0 | 71 |
| 74 | 0 | 17 | 2,727 | 1 | 374 |
| Protein | Taxonomy | tyrosyl-arginyl-phenylalanyl-lysinamide (IC50) | enkephalin, ala(2)-mephe(4)-gly(5)- (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.003 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.2415 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0132 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.004 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0014 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0048 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0283 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, NN; Lemieux, C; Nguyen, TM; Schiller, PW | 1 |
| Meyer, ME | 1 |
| Chiyotani, A; Konno, K; Tagaya, E; Tamaoki, J | 1 |
| Lishmanov, IuB; Maslov, LN; Naryzhnaia, NV | 1 |
| Krylatov, AV; Lishmanov, IuB; Maslov, LN | 1 |
| Lishmanov, IuB; Maslov, LN; Naryzhnaia, NV; Revinskaia, IuG | 2 |
| Bogomaz, SA; Lishmanov, IuB; Maslov, LN; Naumova, AV | 1 |
| Clapp, JF; Kett, A; Omoniyi, AT; Soong, Y; Szeto, HH; Wu, D | 1 |
| Desiderio, DM; Fasolo, J; Fridland, G; Lovelace, JL; Schiller, PW; Soong, Y; Szeto, HH; Wu, D | 1 |
| Lishmanov, IuB; Maslov, LN; Rebrova, TIu; Tam, SV | 1 |
| Gross, GJ; Lasukova, TV; Lishmanov, IuB; Maslov, LN; Tam, SV | 1 |
| Fasolo, J; Soong, Y; Szeto, HH; Wu, D | 1 |
| Ben, Y; Furst, S; Lee, NM; Nguyen, TM; Riba, P; Schiller, PW | 1 |
| Berezowska, I; Bolan, E; Janvey, AJ; Neilan, CL; Nguyen, TM; Pasternak, GW; Schiller, PW | 1 |
| Brun, V; Chuoï-Mariot, MT; Colombel, JF; Desreumaux, P; Dubuquoy, L; Gaveriaux-Ruff, C; Groux, H; Kieffer, BL; Philippe, D | 1 |
| Ben, Y; Lee, NM; Schiller, PW; Smith, AP | 1 |
17 other study(ies) available for tyrosyl-arginyl-phenylalanyl-lysinamide and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Dermorphin analogues carrying an increased positive net charge in their "message" domain display extremely high mu opioid receptor selectivity.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Oligopeptides; Opioid Peptides; Rats; Receptors, Opioid; Receptors, Opioid, mu; Structure-Activity Relationship | 1989 |
Behavioral effects of the mu-opioid peptide agonists DAMGO, DALDA, and PL017 on locomotor activities.
Topics: Amino Acid Sequence; Analgesics; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Male; Molecular Sequence Data; Motor Activity; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1993 |
Stimulation of opioid mu-receptors potentiates beta adrenoceptor-mediated relaxation of canine airway smooth muscle.
Topics: Amino Acid Sequence; Animals; Cyclic AMP; Dogs; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Male; Molecular Sequence Data; Muscle Relaxation; Muscle, Smooth; Oligopeptides; Receptors, Adrenergic, beta; Receptors, Opioid, mu; Trachea | 1995 |
[Cardioprotective effects of stimulation of peripheral mu-opiate receptors, and the role of opiatergic mechanisms in the pathogenesis of stress-induced heart damage].
Topics: Animals; Cardiomyopathies; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Immobilization; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Stress, Physiological | 1997 |
[The anti-arrhythmic effect of the mu-opiate receptor agonists in adrenal arrhythmia: the role of the autonomic nervous system].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Autonomic Nervous System; Electrocardiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Epinephrine; Ganglionic Blockers; Hexamethonium; Male; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu | 1996 |
[The role of peripheral and central mu-opiate receptors in the modulation of adrenergic cardiac lesions during stress].
Topics: Adrenal Glands; Adrenergic Agents; Animals; Brain; Cardiomyopathies; Catecholamines; Diphosphates; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanethidine; Injections, Intraventricular; Male; Myocardium; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Stress, Physiological; Sympathetic Nervous System | 1998 |
[Modulating effect of mu-opioid receptor ligands on adrenergic mechanism of stressor heart damage pathogenesis].
Topics: Animals; Catecholamines; Diphosphates; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Immobilization; Ligands; Male; Myocardium; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Stress, Physiological | 1998 |
[mu-Opiate receptor activation and increase in heart resistance to ischemic and reperfusion injury].
Topics: Animals; Blood Pressure; Electrocardiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Myocardial Ischemia; Myocardial Reperfusion Injury; Narcotic Antagonists; Oligopeptides; Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu | 1998 |
A peripheral site of action for the attenuation of baroflex-mediated bradycardia by intravenous mu-opioid agonists.
Topics: Animals; Anti-Arrhythmia Agents; Baroreflex; Bradycardia; Catheters, Indwelling; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Naloxone; Narcotic Antagonists; Nitroprusside; Norepinephrine; Oligopeptides; Pregnancy; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Sheep | 2000 |
In vivo pharmacokinetics of selective mu-opioid peptide agonists.
Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Oligopeptides; Receptors, Opioid, mu; Sheep | 2001 |
[The role of mu- and delta-opiate receptors in resistance of the myocardium to free radical damage].
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Myocardial Contraction; Myocardium; Oligopeptides; Oxidative Stress; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 2001 |
[Effect of stimulation of mu-opiate receptors on contractility of the isolated heart in normal oxygenation and during ischemia-reperfusion].
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; In Vitro Techniques; Myocardial Contraction; Myocardial Reperfusion Injury; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu | 2001 |
Resensitization of blood pressure response to mu-opioid peptide agonists after acute desensitization.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Oligopeptides; Opioid Peptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep | 2001 |
[Dmt(1)]DALDA is highly selective and potent at mu opioid receptors, but is not cross-tolerant with systemic morphine.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Receptors, Opioid, mu; Spinal Cord; Time Factors | 2002 |
Characterization of the binding of [3H][Dmt1]H-Dmt-D-Arg-Phe-Lys-NH2, a highly potent opioid peptide.
Topics: Alternative Splicing; Analgesics; Animals; Binding Sites; Cattle; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Ions; Mice; Nucleotides; Oligopeptides; Opioid Peptides; Receptors, Opioid, mu; Sulfur Radioisotopes; Tritium | 2003 |
Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; CD4-Positive T-Lymphocytes; Colitis; Colon; Cytokines; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Naloxone; Narcotic Antagonists; Oligopeptides; Peroxidase; Receptors, Opioid, mu; Trinitrobenzenesulfonic Acid | 2003 |
Tolerance develops in spinal cord, but not in brain with chronic [Dmt1]DALDA treatment.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; Mice, Inbred ICR; Oligopeptides; Pain Measurement; Spinal Cord; Tyrosine | 2004 |