tyrosine has been researched along with transforming growth factor alpha in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.08) | 18.7374 |
| 1990's | 29 (60.42) | 18.2507 |
| 2000's | 16 (33.33) | 29.6817 |
| 2010's | 2 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arteaga, CL; Awad, JA; Boland, CR; Coffey, RJ; Kraus, ER; Nanney, LB; Polk, WH; Romano, M; Wargovich, MJ | 1 |
| Cardinali, M; Robbins, KC; Sartor, O | 1 |
| Chandrasekar, B; Korc, M; Shah, GN | 1 |
| Earp, HS; Herman, B; Lee, DC; Massagué, J; McCune, BK; Teixidó, J; Winchell, LF; Wong, ST | 1 |
| Budzilovich, GN; Hayes, RL; Hiesiger, EM; Pierz, DM | 1 |
| Chess, PR; Finkelstein, JN; Ryan, RM | 1 |
| Bermudez, E; Everitt, J; Ferriola, PC; Mangum, J; Stewart, W; Walker, C | 1 |
| Hirota, K; Imai, T; Kurachi, H; Ogren, L; Talamantes, F; Yamaguchi, M | 1 |
| Dutta, S; Fligiel, SE; Majumdar, AP; Ponduri, K; Relan, NK; Saeed, A | 1 |
| Bhaskaran, R; Chen, ST; Jayaraman, G; Kumar, TK; Yu, C; Yu, HM | 1 |
| Bennett, W; Gerwin, BI; Harris, CC; Hui, F; Lupu, R; Murakami, M; Noguchi, M | 1 |
| Arteaga, CL; Halter, SA; Winnier, AR | 1 |
| Baldassare, JJ; Elder, JT; Fisher, GJ; Henderson, PA; Reynolds, NJ; Talwar, HS; Voorhees, JJ | 1 |
| Hajjar, JJ; Oliver, BL; Sha'afi, RI | 1 |
| Batova, A; Creek, KE; Forand, R; MacDonald, LM; Pirisi, L; Zyzak, LL | 1 |
| Fürstenberger, G; Kast, R; Marks, F | 1 |
| Majumdar, AP; Malecka-Panas, E; Relan, NK | 1 |
| Cha, D; Hudson, LG; O'Brien, P; O'Toole, EA; Woodley, DT | 1 |
| Denning, MF; Dlugosz, AA; Magnuson, T; Threadgill, DW; Yuspa, SH | 1 |
| Beug, H; Decker, T; Hayman, MJ; Meinke, A; Mellitzer, G; Wessely, O | 1 |
| Akimoto, S; Gotoh, M; Hirohashi, S; Kanai, Y; Machinami, R; Ochiai, A; Shibata, T; Yasui, N | 1 |
| Boylan, JM; Gruppuso, PA; Lipeski, LE | 1 |
| Boylan, JM; Gruppuso, PA | 1 |
| Epstein, RJ; Gulliford, TJ; Huang, GC; Ouyang, X | 1 |
| Grasso, AW; Kung, HJ; Miller, CM; Pretlow, TG; Rhim, JS; Wen, D | 1 |
| Bongcam-Rudloff, E; El-Obeid, A; Nistér, M; Ostman, A; Sörby, M; Westermark, B | 1 |
| Göke, M; Kanai, M; Lynch-Devaney, K; Podolsky, DK | 1 |
| Fu, YM; Li, YQ; Meadows, GG | 1 |
| Hanai, H; Kajimura, M; Kaneko, E; Kodaira, M; Lin, S; Takeuchi, K | 1 |
| Bowers, G; Dent, P; Logsdon, C; Park, JS; Reardon, DB; Schmidt-Ullrich, R; Valerie, K | 1 |
| Egeblad, M; Jäättelä, M | 1 |
| Cheng, C; Coffey, RJ; Dempsey, PJ; Denning, MF; Dlugosz, AA; Magnuson, T; Threadgill, DW; Yuspa, SH | 1 |
| Hiraoka, S; Kitamura, S; Matsuzawa, Y; Miyazaki, Y; Shinomura, Y; Tsutsui, S | 1 |
| Bali, M; Edelman, A; Fritsch, J; Lipecka, J | 1 |
| Schmidt, M; Wels, W | 1 |
| El-Obeid, A; Hesselager, G; Nistér, M; Westermark, B | 1 |
| Gogg, S; Smith, U | 1 |
| Alexander, AD; Lima, MF; Villalta, F | 1 |
| Kruger, JS; Reddy, KB | 1 |
| Calvisi, DF; Factor, VM; Hironaka, K; Ladu, S; Thorgeirsson, SS | 1 |
| Kishida, O; Kiyohara, T; Miyazaki, T; Miyazaki, Y; Murayama, Y; Ogasa, M; Shimomura, I; Shinomura, Y; Tsutsui, S; Watabe, K; Yamamoto, T | 1 |
| Apodaca, G; Balestreire, EM | 1 |
| Beaulieu, JF; Chailler, P; Ménard, D; Rivard, N; Tétreault, MP | 1 |
| Allet, C; Baroncini, M; Blond, S; Collier, F; Duhem-Tonnelle, V; Junier, MP; Kerr-Conte, J; Loyens, A; Ojeda, SR; Prevot, V; Sharif, A | 1 |
| Akimoto, S; Hirohashi, S; Ino, Y; Ito, H; Ochiai, A; Shomori, K; Shudo, K | 1 |
| Andò, S; Aquila, S; De Amicis, F; De Marco, P; Fuqua, SA; Lappano, R; Maggiolini, M; Sisci, D; Vivacqua, A | 1 |
| Delle Fave, G; Di Florio, A; Jensen, RT; Moreno, P; Sancho, V | 1 |
| Kerperien, J; Meijer, IM; Sotoca, AM; van Leeuwen, JE; van Zoelen, EJ | 1 |
48 other study(ies) available for tyrosine and transforming growth factor alpha
| Article | Year |
|---|---|
Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo.
Topics: Animals; Aspirin; Dinoprostone; Ethanol; Ethylmaleimide; Gastric Mucins; Gastric Mucosa; Image Processing, Computer-Assisted; Indomethacin; Microscopy, Electron, Scanning; Necrosis; Ornithine Decarboxylase; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases; Tyrosine | 1992 |
Suramin, an experimental chemotherapeutic drug, activates the receptor for epidermal growth factor and promotes growth of certain malignant cells.
Topics: Cell Division; ErbB Receptors; Humans; KB Cells; Phosphorylation; Suramin; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1992 |
Differential binding and biological activities of epidermal growth factor and transforming growth factor alpha in a human pancreatic cancer cell line.
Topics: Epidermal Growth Factor; ErbB Receptors; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Pancreatic Neoplasms; Phosphorylation; Statistics as Topic; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1991 |
The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Cell Communication; Cell Line; Cell Membrane; ErbB Receptors; Intracellular Membranes; Microsomes; Molecular Sequence Data; Mutation; Phosphorylation; Phosphotyrosine; Plasmids; Protein Precursors; Signal Transduction; Transfection; Transforming Growth Factor alpha; Transforming Growth Factors; Tyrosine | 1989 |
Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs).
Topics: Adult; Biomarkers, Tumor; ErbB Receptors; Glioblastoma; Humans; Immunohistochemistry; Middle Aged; Phosphotyrosine; Prognosis; Proto-Oncogene Proteins; Receptor, ErbB-2; Survival Rate; Transforming Growth Factor alpha; Tyrosine | 1993 |
Tyrosine kinase activity is necessary for growth factor-stimulated rabbit type II pneumocyte proliferation.
Topics: Adenocarcinoma; Animals; Blotting, Western; Catechols; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Isoflavones; Kinetics; Lung; Male; Molecular Weight; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells.
Topics: Animals; Asbestos, Crocidolite; Blotting, Northern; Cell Division; Cell Line; Cell Line, Transformed; Epidermal Growth Factor; ErbB Receptors; Mesothelioma; Peritoneal Neoplasms; Phosphoproteins; Phosphotyrosine; Radioimmunoassay; Rats; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1995 |
Opposite effects of transforming growth factor alpha and epidermal growth factor on mouse placental lactogen I secretion.
Topics: Animals; Blotting, Western; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Immunohistochemistry; Kinetics; Mice; Phosphotyrosine; Placenta; Placental Lactogen; Pregnancy; Rats; Recombinant Proteins; Transforming Growth Factor alpha; Tyrosine | 1995 |
Identification and evaluation of the role of endogenous tyrosine kinases in azoxymethane induction of proliferative processes in the colonic mucosa of rats.
Topics: Animals; Azoxymethane; Bromodeoxyuridine; Catechols; Cell Division; Colon; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; ErbB Receptors; Immunosorbent Techniques; Intestinal Mucosa; Kinetics; Molecular Weight; Nitriles; Ornithine Decarboxylase; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Transforming Growth Factor alpha; Tyrosine; Tyrphostins | 1995 |
Conformational studies of a synthetic cyclic decapeptide fragment of rat transforming growth factor-alpha.
Topics: Amino Acid Sequence; Animals; Arginine; Circular Dichroism; Computer Graphics; Disulfides; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Peptides, Cyclic; Protein Conformation; Rats; Transforming Growth Factor alpha; Tyrosine | 1995 |
Biological consequences of overexpression of a transfected c-erbB-2 gene in immortalized human bronchial epithelial cells.
Topics: Animals; Blotting, Western; Bronchi; Cell Division; Cell Line; Epidermal Growth Factor; Epithelium; Gene Expression; Humans; In Vitro Techniques; Ki-67 Antigen; Ligands; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Receptor, ErbB-2; RNA, Messenger; Transfection; Transforming Growth Factor alpha; Tyrosine | 1993 |
Pretreatment with vitamin A inhibits transforming growth factor alpha stimulation of human mammary carcinoma cells.
Topics: Breast Neoplasms; Cell Division; ErbB Receptors; Female; Gene Expression; Humans; In Vitro Techniques; Phosphotyrosine; RNA, Messenger; Signal Transduction; Transforming Growth Factor alpha; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vitamin A | 1993 |
Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes.
Topics: Arachidonic Acid; Cells, Cultured; Diglycerides; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Humans; Hydrolysis; Inositol Phosphates; Intracellular Signaling Peptides and Proteins; Keratinocytes; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phosphatidylcholines; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein Kinase C; Proteins; Transforming Growth Factor alpha; Type C Phospholipases; Tyrosine | 1993 |
Transforming growth factor-alpha increases tyrosine phosphorylation of microtubule-associated protein kinase in a small intestinal crypt cell line (IEC-6).
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Cell Line; Chemical Fractionation; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Growth Inhibitors; Intestine, Small; Isoflavones; Molecular Weight; Nitriles; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Thymidine; Transforming Growth Factor alpha; Tyrosine; Tyrphostins | 1994 |
Increased levels and constitutive tyrosine phosphorylation of the epidermal growth factor receptor contribute to autonomous growth of human papillomavirus type 16 immortalized human keratinocytes.
Topics: Antibodies, Monoclonal; Cell Division; Cell Line, Transformed; Culture Media, Conditioned; Culture Media, Serum-Free; Epidermal Growth Factor; ErbB Receptors; Humans; Keratinocytes; Kinetics; Neutralization Tests; Papillomaviridae; Phosphorylation; Skin; Transforming Growth Factor alpha; Tyrosine | 1994 |
Activation of cytosolic phospholipase A2 by transforming growth factor-alpha in HEL-30 keratinocytes.
Topics: Animals; Arachidonic Acids; Biological Transport; Calcium; Cell Line; Cytosol; Enzyme Activation; ErbB Receptors; Humans; Keratinocytes; Mice; Phospholipases A; Phospholipases A2; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tyrosine | 1993 |
Increased activation of EGF-receptor tyrosine kinase by EGF and TGF-alpha in the colonic mucosa of aged rats.
Topics: Aging; Animals; Bombesin; Colon; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; In Vitro Techniques; Intestinal Mucosa; Male; Phosphorylation; Rats; Rats, Inbred F344; Transforming Growth Factor alpha; Tyrosine | 1996 |
Enhanced modulation of keratinocyte motility by transforming growth factor-alpha (TGF-alpha) relative to epidermal growth factor (EGF).
Topics: Cell Movement; Cells, Cultured; DNA; Epidermal Growth Factor; ErbB Receptors; Humans; Keratinocytes; Phosphorylation; Transforming Growth Factor alpha; Tyrosine; Wound Healing | 1996 |
Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta.
Topics: Alleles; Aluminum Compounds; Animals; Animals, Newborn; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; ErbB Receptors; Fluorides; Gene Expression; Genes, ras; GTP-Binding Proteins; Isoenzymes; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Mutagenesis; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins pp60(c-src); Recombinant Proteins; Signal Transduction; Spodoptera; Transfection; Transforming Growth Factor alpha; Tyrosine | 1996 |
Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.
Topics: Base Sequence; Cell Division; Cell Line; Chloramphenicol O-Acetyltransferase; DNA; DNA-Binding Proteins; Erythroid Precursor Cells; Genes, erbB; Humans; Milk Proteins; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-kit; Receptor Protein-Tyrosine Kinases; Receptors, Erythropoietin; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Transcription, Genetic; Transforming Growth Factor alpha; Tryptophan-tRNA Ligase; Tyrosine | 1996 |
Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells.
Topics: Animals; beta Catenin; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Receptor, ErbB-2; Recombinant Proteins; Sequence Deletion; Signal Transduction; Stomach Neoplasms; Trans-Activators; Transfection; Transforming Growth Factor alpha; Transplantation, Heterologous; Tyrosine | 1996 |
A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor alpha and epidermal growth factor in cultured fetal rat hepatocytes.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Densitometry; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Immunoblotting; Liver; Mitogens; Phosphorylation; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Thymidine; Time Factors; Transforming Growth Factor alpha; Tyrosine | 1996 |
A comparative study of the hepatic mitogen-activated protein kinase and Jun-NH2-terminal kinase pathways in the late-gestation fetal rat.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Female; Gestational Age; GRB2 Adaptor Protein; Hepatocyte Growth Factor; JNK Mitogen-Activated Protein Kinases; Liver; Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Tyrosine | 1996 |
Reduced ability of transforming growth factor-alpha to induce EGF receptor heterodimerization and downregulation suggests a mechanism of oncogenic synergy with ErbB2.
Topics: Antibodies; Antibody Specificity; Carcinoma, Squamous Cell; Dimerization; Down-Regulation; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Humans; Immunoblotting; Ligands; Phosphorylation; Precipitin Tests; Receptor, ErbB-2; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1997 |
ErbB kinases and NDF signaling in human prostate cancer cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma; Cell Division; DNA-Binding Proteins; Enzyme Activation; ErbB Receptors; Glycoproteins; Humans; Isoenzymes; Male; Milk Proteins; Mitogen-Activated Protein Kinases; Neuregulins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Proteins; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Transforming Growth Factor alpha; Transplantation, Heterologous; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1997 |
Cell scattering and migration induced by autocrine transforming growth factor alpha in human glioma cells in vitro.
Topics: Antibodies, Monoclonal; Blotting, Northern; Cell Movement; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Glioblastoma; Humans; Ligands; Phosphorylation; Precipitin Tests; RNA, Messenger; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1997 |
Rapid mitogen-activated protein kinase activation by transforming growth factor alpha in wounded rat intestinal epithelial cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Culture Media, Conditioned; Enzyme Activation; Epithelial Cells; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Rats; Transforming Growth Factor alpha; Tyrosine | 1998 |
Influence of tyrosine and phenylalanine limitation of cytotoxicity of chimeric TGF-alpha toxins on B16BL6 murine melanoma in vitro.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Membrane; Culture Media; Epidermal Growth Factor; Heparin; Melanoma; Mice; Phenylalanine; Proteoglycans; Recombinant Fusion Proteins; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1998 |
Functional muscarinic m3 receptor expressed in gastric cancer cells stimulates tyrosine phosphorylation and MAP kinase.
Topics: Atropine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Densitometry; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Naphthalenes; Phosphorylation; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1999 |
Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell dea
Topics: Antibodies; Breast Neoplasms; Butadienes; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma; Carcinoma, Squamous Cell; Cell Death; Cell Division; DNA, Antisense; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Nitriles; Phosphorylation; Protein Kinases; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1999 |
Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells.
Topics: Breast Neoplasms; Cell Count; Cell Death; Cell Size; Culture Media, Serum-Free; ErbB Receptors; Female; Humans; Ligands; Neuregulin-1; Phosphorylation; Receptor, ErbB-2; Signal Transduction; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes.
Topics: Animals; Calcium; Cell Differentiation; Cells, Cultured; Epidermal Cells; Epidermis; ErbB Receptors; Isoenzymes; Keratinocytes; Mice; Mice, Knockout; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Receptor Cross-Talk; Transforming Growth Factor alpha; Tyrosine | 2000 |
Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells.
Topics: Amphiregulin; Animals; Blotting, Western; Culture Media, Serum-Free; DNA, Complementary; EGF Family of Proteins; Epidermal Growth Factor; ErbB Receptors; Gastric Mucosa; Gene Expression Regulation; Glycoproteins; Growth Substances; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ligands; Oxidative Stress; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-met; Rats; Rats, Wistar; Receptor, ErbB-2; Receptor, ErbB-3; RNA, Messenger; Transfection; Transforming Growth Factor alpha; Tyrosine | 2001 |
Regulation of ClC-2 chloride channels in T84 cells by TGF-alpha.
Topics: Biological Transport; Cell Line; Chloride Channels; Chromones; Colon; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Morpholines; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protons; Signal Transduction; Sodium; Tetraethylammonium; Transforming Growth Factor alpha; Tyrosine | 2001 |
Replacement of N-terminal portions of TGF-alpha with corresponding heregulin sequences affects ligand-induced receptor signaling and intoxication of tumor cells by chimeric growth-factor toxins.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Bacterial Toxins; Binding, Competitive; Cell Survival; Culture Media, Serum-Free; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Exotoxins; Ligands; Molecular Sequence Data; Mutation; Neuregulin-1; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Pseudomonas aeruginosa Exotoxin A; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Time Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Virulence Factors | 2002 |
TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor.
Topics: Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cell Division; DNA, Complementary; Enzyme Inhibitors; ErbB Receptors; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; RNA; RNA, Messenger; Tetracycline; Time Factors; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2002 |
Epidermal growth factor and transforming growth factor alpha mimic the effects of insulin in human fat cells and augment downstream signaling in insulin resistance.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Insulin; Insulin Resistance; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Subcellular Fractions; Transforming Growth Factor alpha; Tyrosine | 2002 |
Transforming growth factor alpha binds to Trypanosoma cruzi amastigotes to induce signaling and cellular proliferation.
Topics: Animals; Cell Division; DNA; Epidermal Growth Factor; ErbB Receptors; Macrophages; Phosphorylation; Signal Transduction; Transforming Growth Factor alpha; Trypanosoma cruzi; Tyrosine | 2003 |
Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells.
Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; rho-Associated Kinases; Transforming Growth Factor alpha; Tyrosine | 2003 |
Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer.
Topics: Animals; Antioxidants; Disease Models, Animal; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Transgenic; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-myc; Transforming Growth Factor alpha; Tyrosine; Vitamin E | 2004 |
Gefitinib (Iressa, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.
Topics: Amphiregulin; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Drug Screening Assays, Antitumor; EGF Family of Proteins; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Glycoproteins; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Irinotecan; Phosphorylation; Quinazolines; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms; Transforming Growth Factor alpha; Tyrosine | 2005 |
Apical epidermal growth factor receptor signaling: regulation of stretch-dependent exocytosis in bladder umbrella cells.
Topics: Animals; Antibodies, Monoclonal; Cell Membrane; Cycloheximide; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Exocytosis; Female; Glycoproteins; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Mucous Membrane; Phosphorylation; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Signal Transduction; Transforming Growth Factor alpha; Tyrosine; Urinary Bladder | 2007 |
Epidermal growth factor receptor-dependent PI3K-activation promotes restitution of wounded human gastric epithelial monolayers.
Topics: Cell Culture Techniques; Cell Movement; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Stomach; Transforming Growth Factor alpha; Tyrosine; Wound Healing | 2008 |
Differential erbB signaling in astrocytes from the cerebral cortex and the hypothalamus of the human brain.
Topics: Analysis of Variance; Astrocytes; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Cerebral Cortex; ErbB Receptors; Excitatory Amino Acid Transporter 1; Fetus; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Hypothalamus; Immunoprecipitation; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neuregulin-1; Receptor, ErbB-4; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor alpha; Tyrosine; Vimentin | 2009 |
Tyrosine-phosphorylation of the 12th armadillo-repeat of beta-catenin is associated with cadherin dysfunction in human cancer.
Topics: Antibodies, Monoclonal; beta Catenin; Blotting, Western; Cadherins; Cell Adhesion; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Immunoprecipitation; Neoplasm Invasiveness; Phosphorylation; Polymerase Chain Reaction; Receptor, ErbB-2; Stomach Neoplasms; Transforming Growth Factor alpha; Tyrosine | 2009 |
G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells.
Topics: Cell Line, Tumor; Estrogen Receptor alpha; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Transcription Factor AP-1; Transcriptional Activation; Transforming Growth Factor alpha; Tyrosine; Up-Regulation | 2009 |
Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.
Topics: Adenoma, Islet Cell; Animals; Blotting, Western; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Gastrointestinal Hormones; Humans; Neuroendocrine Tumors; Pancreatic Neoplasms; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction; Somatostatinoma; Transcriptional Activation; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 2013 |
The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation.
Topics: 14-3-3 Proteins; Endopeptidases; Endosomal Sorting Complexes Required for Transport; Epidermal Growth Factor; ErbB Receptors; HEK293 Cells; Humans; Mutagenesis; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Serine; src-Family Kinases; Transforming Growth Factor alpha; Tyrosine; Ubiquitin Thiolesterase | 2013 |