tyrosine has been researched along with threonine in 811 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 288 (35.51) | 18.7374 |
| 1990's | 157 (19.36) | 18.2507 |
| 2000's | 215 (26.51) | 29.6817 |
| 2010's | 104 (12.82) | 24.3611 |
| 2020's | 47 (5.80) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Katayama, H; Muramatsu, K; Yamamoto, Y | 1 |
| Datta, K; Ghosh, JJ | 1 |
| Prasad, M | 1 |
| Goldsmith, LA | 1 |
| Ashman, PU; Newport, GR; Page, CR; Seed, JR; Stibbs, HH | 1 |
| Bodanszky, M; Martinez, J; Tolle, JC | 1 |
| Bertolini, AM; Santagostino, A | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Cavadore, JC; Coletti-Previero, MA; Previero, A; Torreilles, J | 1 |
| Bantzer, P; Jäkel, A; Liappis, N | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 2 |
| De Santo, NG; Giordano, C; Pluvio, M | 1 |
| White, PJ | 1 |
| Daniel, J | 1 |
| Aguirre, A; Fischer, JE; Funovics, JM; James, JH; Keane, JM; Wesdorp, RI; Westman, T; Yoshimura, N | 1 |
| Bury, KD; Grayston, M; Kanarens, J | 1 |
| Bayley, HS; Chavez, ER | 1 |
| Muramatsu, K; Orita, Y; Yamamoto, Y | 1 |
| Andersen, AE; Avins, L | 1 |
| Arito, T; Muramatsu, K; Tsuda, H | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Chellemi, F | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Goodfellow, JM; Morris, AS; Thanki, N | 1 |
| Countaway, JL; Davis, RJ; Nairn, AC | 1 |
| Barrett, CB; Erikson, E; Maller, JL | 1 |
| Heidecker, G; Kölch, W; Morrison, DK; Rapp, UR | 1 |
| Her, JH; L'Allemain, G; Sturgill, TW; Weber, MJ; Wu, J | 1 |
| Adams, PD; Parker, PJ | 1 |
| Ishida, Y; Kawahara, Y; Koide, M; Tsuda, T; Yokoyama, M | 1 |
| Charbonneau, H; Cool, DE; Fischer, EH; Tonks, NK | 1 |
| Gu, Y; Morgan, DO; Rosenblatt, J | 1 |
| Akanuma, Y; Chatani, Y; Izumi, T; Kadowaki, T; Kasuga, M; Kohno, M; Tamemoto, H; Tobe, K; Ueki, K; Yazaki, Y | 1 |
| Hunter, T; Lindberg, RA; Quinn, AM | 1 |
| Hirayama, T; Oka, A | 1 |
| Cooper, JA; Posada, J | 1 |
| Maggio, R; Palmer, JR; Vogel, Z; Wess, J | 1 |
| Marin, O; Meggio, F; Perich, JW; Pinna, LA | 1 |
| Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D | 1 |
| Chan, T; Lee, M; Sakmar, TP | 1 |
| Betz, A; Hofsteenge, J; Stone, SR | 1 |
| Dent, P; Haystead, CM; Haystead, TA; Sturgill, TW; Wu, J | 1 |
| Ammerer, G; Gartner, A; Nasmyth, K | 1 |
| Bordin, L; Clari, G; Moret, V | 1 |
| Avruch, J; Brautigan, DL; Ingebritsen, TS; Kyriakis, JM | 1 |
| Krek, W; Nigg, EA | 1 |
| Brann, MR; Gdula, D; Wess, J | 1 |
| Akanuma, Y; Gotoh, Y; Hara, K; Kadowaki, T; Koshio, O; Momomura, K; Nishida, E; Tamemoto, H; Tobe, K; Ueki, K | 1 |
| Boulton, TG; Cobb, MH; Robbins, DJ | 1 |
| Bird, TA; Saklatvala, J | 1 |
| Mendelsohn, J; Peacock, JS; Sunada, H; Yu, P | 1 |
| Anderson, SR; Malencik, DA; Zhao, ZZ | 1 |
| Iwashita, S; Mitsui, K | 1 |
| Laudano, AP; Liptak, LM; McGrew, BR; Perron, DC; Peters, DJ | 1 |
| Kanner, SB; Parsons, JT; Reynolds, AB; Vines, RR; Wang, HC | 1 |
| Abdel-Ghany, M; Koland, J; Racker, E; Revis-Gupta, S | 1 |
| Breckenridge, MB; Grants, IS; Liu, BQ; Newhouse, YG; Walters, JD; Whisler, RL | 1 |
| Dickens, M; Tavaré, JM | 1 |
| Alengrin, F; Ballotti, R; Dull, T; Lammers, R; Schlessinger, J; Tartare, S; Ullrich, A; Van Obberghen, E | 1 |
| Bowen, S; Davis, RJ; Selva, E; Stanley, K | 1 |
| Beidler, DR; Stern, DF; Zerillo, C; Zheng, P | 1 |
| Bednarek, MA; Engl, SA; Gammon, MC; Lindquist, JA; Porter, G; Williamson, AR; Zweerink, HJ | 1 |
| Kanner, SB; Parsons, JT; Reynolds, AB; Vines, RR; Wu, H | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Asao, H; Nagata, K; Nakamura, M; Sugamura, K; Takeshita, T | 1 |
| Deuel, TF; Shawver, LK | 1 |
| Clari, G; Marzaro, G; Moret, V | 1 |
| Goodfellow, JM; Thanki, N; Thornton, JM | 1 |
| Chinami, M; Goto, M; Ohtsu, Y; Shingu, M; Yuge, K | 1 |
| Aitken, A; Morrice, N | 1 |
| Etheredge, RW; Glimcher, MJ | 1 |
| Colca, JR; McCroskey, MC; Pearson, JD | 1 |
| Boland, D; Goren, HJ; Neufeld, E | 1 |
| Gjika, HB; Levine, L; Van Vunakis, H | 1 |
| Botting, HG; Peace, RW; Sarwar, G | 1 |
| Adlakha, RC; Kuang, J; Rao, PN; Zhao, JY | 1 |
| Pessin, JE; Treadway, JL; Whittaker, J | 1 |
| Beale, D; Coadwell, J | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Lu, PW; Tao, M | 1 |
| Cooper, JA; Hunter, T | 1 |
| Boynton, AL; Raptis, L; Whitfield, JF | 1 |
| Corvera, S; Czech, MP; Davis, RJ; Lewis, RE; MacDonald, RG; Mottola, C; Necessary, PC; Yu, KT | 1 |
| Cooper, JA; King, CS | 1 |
| Herrera, R; Rosen, OM | 1 |
| de Boer, JE; Janssen, MA; Oostenbroek, RJ; Soeters, PB; van Dongen, JJ | 1 |
| Kuyl-Yeheskiely, E; Schaeffer, AH; Tromp, CM; van Boom, JH; van der Marel, GA | 1 |
| Bertics, PJ; Gill, GN; Santon, JB | 1 |
| Gerber, GE; Morton, RC | 1 |
| Christensen, HN; Vadgama, JV | 1 |
| Yokogoshi, H | 1 |
| Johansen, JT; Livingston, DM; Vallee, BL | 1 |
| Bryce, GF | 1 |
| Kasarian, BA | 1 |
| Jaton, JC | 1 |
| Bundgaard, L; Winther, A | 1 |
| Braun, W; Weiss, C; Zschaler, W | 1 |
| Dziewiatkowski, DD; Hascall, VC; Riolo, RL | 1 |
| Manahan, J; Mandl, I | 2 |
| Hirsh, DI; Lipmann, F | 1 |
| Beerens, H; Garcia, C | 1 |
| Erikson, E; Erikson, RL | 1 |
| Karadźić, V; Micić, D; Rakić, L | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Kuhn, J; Somerville, RL | 1 |
| Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
| Mandel, P; Trayhurn, P; Virmaux, N | 1 |
| Allsopp, MN; Hullin, RP; Rees, JR | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Lindig, OH; Mitlin, N; Thompson, AC; Wiygul, G | 1 |
| Jäkel, A; Liappis, N | 1 |
| Ambani, LM; Liu, YP; Van Woert, MH | 1 |
| Crossley, AC; Evans, PD | 1 |
| Bergen, WG; Potter, EL | 1 |
| Housman, DE; Temple, GF | 1 |
| Arregui, A; Bennett, JP; Logan, WJ; Snyder, SH | 1 |
| Castillo, CL; Mayer, A; Ogawa, S; Shulman, RG | 1 |
| Bergen, WG; Isoun, TT; Whitehair, CK | 1 |
| Sunde, ML | 1 |
| Chase, R; Gillam, IC; Tener, GM | 1 |
| Daniel, V; Grimberg, JI | 1 |
| Halpern, YS | 1 |
| Pittsyn, OB | 1 |
| Rees, MW; Short, MN | 1 |
| Eccleston, M; Kelly, DP | 1 |
| Araya, A; Goodman, M; Maita, T; Matsuda, G; Ota, H; Prychodko, W; Watanabe, B | 1 |
| Bergner, H; Münchmeyer, R; Simon, O | 1 |
| Bradbury, JH; Ley, KF | 1 |
| Good, RA; Jose, DG | 1 |
| Yu, WL | 1 |
| Oldendorf, WH | 2 |
| Gruber, L; Harris, JE | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Bemiller, JN; Hoffmann, WE; Pappelis, AJ | 1 |
| Spray, GH; Williams, DL | 1 |
| Adamson, I; Fisher, H | 1 |
| Lowenstein, LM; Mayers, AM; Toback, FG | 1 |
| Pedersen, RA; Spindle, AI | 1 |
| Gabrial, GN; Hussein, L; Morcos, SR | 1 |
| Dobrev, ID; Krysteva, MA; Mancheva, IN | 1 |
| Fridkin, M; Goren, HJ | 1 |
| Giorgio, AJ; Linarelli, LG; Macdonald, RR; Rubin, HM | 1 |
| Litwin, J | 1 |
| Huang, HT | 1 |
| Sakiyama, F | 1 |
| Iwashima, A; Kawasaki, T; Nakamura, M; Nose, Y | 1 |
| Berger, H; Yanofsky, C | 1 |
| Ilan, J | 1 |
| Sekiya, T; Ukita, T | 1 |
| Benevenga, NJ; Harper, AE; Wohlhueter, RM | 1 |
| Hunt, DE | 2 |
| Kojima, H; Sugae, K | 1 |
| Bolinder, AE | 2 |
| Beuvery, EC; Dijk, J; Gruber, M; Konings, WN; Wichertjes, T | 1 |
| Goldman, M; Griffin, AC | 1 |
| Bennett, JC; Habeeb, AF; Schrohenloher, RE | 1 |
| Cahill, CF; Felig, P; Marliss, E; Ohman, JL | 1 |
| Bourrillon, R; Jouanneau, J; Razafimahaleo, E | 1 |
| Abel, CA; Grey, HM; Prahl, JW | 1 |
| Bennick, A; Connell, GE | 1 |
| Peterson, NA; Raghupathy, E | 1 |
| Boling, JA; Bradley, NW; Willard, JC | 1 |
| Nagchaudhuri, J; Ozalp, I; Scrimshaw, NS; Tontisirin, K; Young, VR | 1 |
| Barry, LG; Coletti-Previero, MA; Previero, A | 1 |
| Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
| Ono, T; Tasaki, I | 1 |
| Meade, RJ; Pick, RT | 1 |
| Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
| Austic, RE; Nesheim, MC | 1 |
| Fairwell, T; Lovins, RE | 1 |
| Fernstrom, JD; Larin, F; Wurtman, RJ | 1 |
| Barkin, E; Levy, HL | 1 |
| Shearer, TR; Suttie, JW | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Conti, G; Modis, L; Modis-Süveges, J; Spreca, A | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
| Gallo, RC; Pestka, S | 1 |
| Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
| Appella, E; Martin, RG; Voll, MJ | 1 |
| Municio, AM; Vega, A | 1 |
| Kapoor, IJ; Tandon, RN | 1 |
| Dusek, Z; Hradec, J | 1 |
| Hoshino, S; Tsubota, H | 1 |
| Ermol'eva, ZV; Pokidova, NV; Zhuravleva, TP | 1 |
| Fuchs, G; Oepen, H; Oepen, I | 1 |
| Hatano, M; Obara, Y; Ono, S | 1 |
| Feldheim, W | 1 |
| D'Mello, JP; Lewis, D | 2 |
| Palo, J; Saifer, A | 1 |
| Blackburn, MN; Chatterjee, GC; Noltmann, EA; Pon, NG; Schnackerz, KD | 1 |
| Lohrenz, FN; Tewksbury, DA | 1 |
| Grimble, RF; Whitehead, RG | 1 |
| Neuhoff, V; Weise, M | 1 |
| Zaetz, TL | 1 |
| Hegsted, DM; Said, AK | 1 |
| Meade, RJ; Nordstrom, JW; Stockland, WL; Typpo, JT | 1 |
| McKean, CM; Peterson, NA | 2 |
| Melcher, G | 1 |
| Becker, JW; Simpson, PG; Thathachari, YT | 1 |
| Anderson, JW; Fewden, L | 1 |
| Theuer, RC | 1 |
| Jones, JD; Ulrich, JA; Winkelmann, RK | 1 |
| King, L; Perham, RN | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Kerly, M; Spruyt, JE | 1 |
| Frolova, VI; Katrukha, GS; Kuzovkov, AD | 1 |
| Williams, JN | 1 |
| Flory, B; Krassner, SM | 1 |
| Debusk, AG; Wolfinbarger, L | 1 |
| Gusev, EI | 1 |
| Ansorge, S; Bohley, P | 1 |
| Schröder, I | 1 |
| Hageman, EC; Larson, BL; Schingoethe, DJ | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Nakahara, M; Yamada, S | 1 |
| Chain, RK; Matsubara, H; Sasaki, RM | 1 |
| Brown, HH | 1 |
| Meun, DH; Smith, KC | 1 |
| Holman, G; Lowe, JS; Morley, JS; Smithers, MJ | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Bairos, MA; Bairos, VA | 1 |
| Ota, S | 1 |
| Samofalova, MS | 1 |
| Gulian, EA; Kazarian, BA | 1 |
| Baker, DH; Scott, HM; Sugahara, M | 1 |
| Landau, RL; Lugibihl, K | 2 |
| Beisel, WR; Dangerfield, HG; Feigin, RD | 1 |
| Gross, S; Maskaleris, ML; Milhorat, AT | 1 |
| Abdel Kader, MM; Abdel Wahab, F; Ata, AA; Emara, SH; Soliman, L | 1 |
| Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
| Menden, E; Vangala, RR | 1 |
| Carruthers, C | 1 |
| Gineitis, AA; Vinogradova, IA; Vorobyev, VI | 1 |
| Ganguly, J; Malathi, P | 1 |
| Dennis, ES; Goodchild, CG | 1 |
| Haynes, WD; Taylor, AE | 1 |
| Alam, SQ; Becker, RV; Harper, AE; Rogers, QR; Stucki, WP | 1 |
| Alam, SQ; Harper, AE; Rogers, QR | 1 |
| Huang, JM; Wang, IS; Wang, KT | 1 |
| Gurley, LR; Kischer, CW; Shepherd, GR | 1 |
| Ebata, M; Otsuka, H; Takahashi, Y | 1 |
| Aurich, H | 1 |
| Gutermann, H; Waldschmidt-Leitz, E | 1 |
| Frolova, VI; Iulikova, EP; Kuzovkov, AD; Oparysheva, EF | 1 |
| Andreeva, LA | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Bourke, JB; Massey, LM; Stillings, BR | 1 |
| Adamson, LF; Ingbar, SH | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Rigby, BJ | 1 |
| Estes, FL; Wetzel, RL | 1 |
| Scott, HM; Zimmerman, RA | 2 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Hill, DC; Shao, TC | 1 |
| Efron, ML; Mechanic, GL; Shih, VE | 1 |
| Oliver, IT; Yeung, D | 1 |
| Godin, C | 1 |
| Abasov, IT | 1 |
| Anderson, GH | 1 |
| Fujitaki, JM; Smith, RA; Yang, JC | 1 |
| Cozzone, AJ; Manai, M | 1 |
| Congote, LF | 1 |
| Capony, JP; Demaille, JG | 1 |
| Chang, WC; Chou, CK; Lee, ML; Lee, SC | 1 |
| De Groot, N; Galski, H; Hochberg, AA; Ilan, J | 1 |
| Martensen, TM | 1 |
| Carbone, A; Kaiser, A; Scheidtmann, KH; Walter, G | 1 |
| Gazzano, H; Kowalski, A; van Obberghen, E | 1 |
| Janjua, NA; MacGibbon, B; Metrakos, JD; Metrakos, K; van Gelder, NM | 1 |
| Castro, JV; Norton, PM; Sansaricq, C; Snyderman, SE | 1 |
| Barker, HA | 1 |
| Wold, F | 1 |
| Inokuchi, K; Kanashima, R; Nagasue, N | 1 |
| Blouin, MJ; Gutowski, NJ; Ludwig, R; Noble, M; Pröschel, C | 1 |
| Bagrodia, S; Chackalaparampil, I; Shalloway, D | 1 |
| Johns, RB; Meggio, F; Perich, JW; Pinna, LA; Reynolds, EC; Valerio, RM | 1 |
| Adams, V; McCabe, ER; Schieber, A | 1 |
| Davis, RJ; Dickens, M; Gupta, S; Han, J; Raingeaud, J; Rogers, JS; Ulevitch, RJ | 1 |
| Feinstein, R; Hemi, R; Kanety, H; Karasik, A; Papa, MZ | 1 |
| Cook, JG; Ma, D; Thorner, J | 1 |
| Campbell, MS; Gorbsky, GJ; Taagepera, S | 1 |
| Barry, PH; Cunningham, AM; French, PW; Pierce, KD; Rajendra, S; Schofield, PR; Vandenberg, RJ | 1 |
| Carr, AM; Den Haese, GJ; Gould, KL; Walworth, N | 1 |
| Hyre, DE; Spicer, LD | 1 |
| Iida, M; Imanaka, T; Ito, K; Jinnouchi, H; Kamohara, S; Kan, M; Kanai, F; Nishioka, Y; Ohnishi, T; Todaka, M | 1 |
| Fischer, WH; Hunter, T; Lindberg, RA | 1 |
| Crovello, CS; Furie, B; Furie, BC | 1 |
| Blenis, J; Chen-Kiang, S; Li, HC; Schindler, C; Zhang, X | 1 |
| Hase, T; Kambayashi, J; Mori, T; Murata, K; Okuyama, M; Sakon, M | 1 |
| Lauzé, E; Luca, FC; Schutz, AR; Stoelcker, B; Weiss, E; Winey, M | 1 |
| Beato, M; Dunkel, R; Suske, G; Vriend, G | 1 |
| Offer, G; Sessions, R | 1 |
| Beaudet, A; Botto, JM; Chabry, J; Mazella, J; Nouel, D; Vincent, JP | 1 |
| Heller, A; Isakov, N; Ofir, R; Rager-Zisman, B; Salzberg, S; Segev, Y; Udem, S; Weinstein, Y; Wolfson, M | 1 |
| Dell, KR; Engel, JN | 1 |
| Baccara, MT; Grigorescu, F; Renard, E; Rouard, M | 1 |
| Wüthrich, K | 1 |
| Grémeaux, T; Le Marchand-Brustel, Y; Tanti, JF; van Obberghen, E | 1 |
| Arola, LI; Salvadó, MJ | 1 |
| Capeau, J; Caron, M; Cherqui, G; Picard, J; Reynet, C; Wicek, D | 1 |
| Fersht, AR; First, EA | 1 |
| Merbs, SL; Nathans, J | 1 |
| Decker, SJ; Pang, L; Saltiel, AR | 1 |
| Erikson, E; Fridman, H; Granot, Y; Maller, JL; Schrier, RW; Van Putten, V; Williams, B | 1 |
| Ruderman, JV; Zheng, XF | 1 |
| Dailey, D; Lim, MY; Martin, GS; Thorner, J | 1 |
| Behravan, G; Jonsson, BH; Liang, Z; Lindskog, S; Xue, Y | 1 |
| Honda, R; Nagata, A; Ohba, Y; Okayama, H; Yasuda, H | 1 |
| Atherton-Fessler, S; Geahlen, RL; Parker, LL; Piwnica-Worms, H | 1 |
| Hunter, T; Kakizuka, A; Sebastian, B | 1 |
| Combettes, M; Ferre, P; Issad, T | 1 |
| Ashworth, A; King, AG; Ozanne, BW; Smythe, C | 1 |
| Brann, MR; Burstein, ES; Spalding, TA | 1 |
| Crimmins, DL; Joyal, JL; Sacks, DB; Thoma, RS | 1 |
| Demuth, HU; Diefenthal, T; Grosche, G; Kaspari, A; Schierhorn, A | 1 |
| Hunter, T; Jiang, W; Poon, RY; Toyoshima, H | 1 |
| Kosk-Kosicka, D; Li, Z; Lopez, MM; Sacks, DB | 1 |
| Barford, D | 1 |
| Chae, SW; Cho, KP; Kwak, YG; Park, SK | 1 |
| Jonas, EA; Kaczmarek, LK | 1 |
| Auguste, P; Froger, J; Gascan, H; Olivier, C; Pouplard-Barthelaix, A; Praloran, V; Robledo, O | 1 |
| Barry, TN; McNabb, WC; Moughan, PJ; Yu, F | 1 |
| Adomeit, A; Boehmer, A; Boehmer, FD; Graness, A; Kovalenko, M; Liebmann, C; Nürnberg, B; Steinmetzer, T; Wetzker, R | 1 |
| Artçanuthurry, V; Grelac, F; Levy-Tolédano, S; Maclouf, J; Martin-Cramer, E | 1 |
| Ullrich, A; Vogel, W | 1 |
| Londos, C; Rondinone, CM; Smith, UP; Zarnowski, MJ | 1 |
| Bishop, GA; Grose, C; Olson, JK | 1 |
| Böhm, SK; Bunnett, NW; Grady, EF; Khitin, LM; Payan, DG; Smeekens, SP | 1 |
| Dohse, B; Mathis, P; Oesterhelt, D; Ortega, JM | 1 |
| Hall, RA; Soderling, TR | 1 |
| Bazarsky, E; Blagerman, S; Hunter, T; Ofir, R; Rager-Zisman, B; Weinstein, Y; Wolfson, M | 1 |
| Castanon, F; Parsons, CM; Wang, X | 1 |
| Chen, RH; Derynck, R; Feng, XH; Griswold-Prenner, I; Lawler, S; Maruoka, EM; Turck, CW | 1 |
| Dabrosin, C; Hallström, A; Hammar, M; Ungerstedt, U | 1 |
| Dolginov, Y; Hanoch, T; Lando, Z; Michael, D; Roubini, E; Rubinfeld, H; Seger, R; Yao, Z; Yung, Y; Zharhary, D | 1 |
| Jenab, S; Morris, PL | 1 |
| Poon, RY | 1 |
| Meighan-Mantha, RL; Riegel, AT; Wellstein, A | 1 |
| Gibson, DM; Ogris, E; Pallas, DC | 1 |
| Canagarajah, BJ; Cobb, MH; Goldsmith, EJ; Khokhlatchev, A | 1 |
| Chau, MS; Hunter, T; Poon, RY; Yamashita, K | 1 |
| Guesdon, F; Knight, CG; Rawlinson, LM; Saklatvala, J | 1 |
| Freestone, P; Norris, V; Nyström, T; Trinei, M | 1 |
| Baldin, V; Cans, C; Ducommun, B; Knibiehler, M | 1 |
| Alzari, PM; Cole, ST; Guillouard, I; Saliou, B | 1 |
| Aboulafia-Etzion, S; Aharonovitz, O; Battler, A; Granot, Y; Leor, J | 1 |
| Iizuka, T; Ishibashi, T; Kokawa, K; Watanabe, R; Yamamoto, A | 1 |
| Cummings, RD; Kang, J; Kishimoto, TK; Liu, W; McEver, RP; Ramachandran, V | 1 |
| Aldrich, HC; Ferry, JG; Maupin-Furlow, JA | 1 |
| Booher, RN; Fattaey, A | 1 |
| Ellis, MK; Gaskin, P; Lock, EA; Provan, WM; Robinson, M; Smith, LL | 1 |
| Klessig, DF; Zhang, S | 1 |
| Braus, GH; Krappmann, S; Schnappauf, G | 1 |
| Kotovych, G; McClung, RE; Nakashima, TT | 1 |
| Burus, I; Decsi, T; Veitl, V | 1 |
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| Arlinghaus, RB; Sun, T | 1 |
| Siegel, JN | 1 |
| Bártová, I; Koca, J; Otyepka, M | 1 |
| Choi, MY; Hur, JY; Jung, JW; Kang, GY; Kim, KP; Park, SH | 1 |
| Chari, R; Jin, J; Kunapuli, SP; Murugappan, S; Palli, VM | 1 |
| Gnad, F; Jensen, PR; Macek, B; Mann, M; Mijakovic, I; Petranovic, D; Soufi, B | 1 |
| Appaji Rao, N; Bhavani, BS; Bisht, S; Kaul, P; Murthy, MR; Prakash, V; Rajaram, V; Savithri, HS | 1 |
| Hawley, JA; Lessard, SJ; Reeder, DW; Rivas, DA; Saito, M; Yaspelkis, BB | 1 |
| Kalkhof, S; Sinz, A | 1 |
| Andreazza, HJ; Bilusich, D; Bowie, JH; Eichinger, PC; Fitzgerald, M; Hoffmann, P; Hoffmann, R | 1 |
| Agard, DA; Ho, BK | 1 |
| Hwang, CS; Varshavsky, A | 1 |
| Goto, K; Kagenishi, T; Kawano, T; Yokawa, K | 1 |
| Askari, N; Beenstock, J; Engelberg, D; Livnah, O | 1 |
| Cook, KE; Dall'acqua, WF; Damschroder, MM; Oganesyan, V; Woods, RM; Wu, H | 1 |
| Aivaliotis, M; Gnad, F; Macek, B; Mann, M; Oesterhelt, D; Reichelt, P | 1 |
| Appella, E; Ashwell, JD; Mittelstadt, PR; Yamaguchi, H | 1 |
| Higashimae, N; Hori, S; Kakizuka, A; Kato, N; Kimura, Y; Koike, M; Maeda, R; Mori-Konya, C; Noguchi, M; Ohizumi, H; Yasuda, K | 1 |
| Landry, CR; Levy, ED; Michnick, SW | 1 |
| Bowser, R; Caltagarone, J; Jing, Z | 1 |
| Ishihama, Y; Ravichandran, A; Sugiyama, N; Swarup, S; Tomita, M | 1 |
| Andreazza, HJ; Bilusich, D; Bowie, JH; Hoffmann, P; Wang, T | 1 |
| Rao, R | 1 |
| Aitken, RJ; Baker, MA; Curry, B; Hetherington, L | 1 |
| Aoyama, H; Bruni-Cardoso, A; de Carvalho, HF; Ferreira, CV; Granjeiro, JM; Peppelenbosch, MP; Zambuzzi, WF | 1 |
| Blouet, C; Jo, YH; Li, X; Schwartz, GJ | 1 |
| Albertini, V; Benussi, L; Bernardini, S; Binetti, G; Bruno, A; Cassetta, E; Ghidoni, R; Paterlini, A; Rossini, PM; Squitieri, F; Squitti, R | 1 |
| Frawley Cass, SM; Reid, GE; Tepe, JJ | 1 |
| Eng, JK; Han, DK; Hwang, SI; Lundgren, DH; Mayya, V; Rezaul, K; Rodionov, V; Wu, L | 1 |
| Cimen, H; Koc, EC; Koc, H; Miller, JL | 1 |
| Chen, MM; Lee, CY; Leland, HA; Silletti, S | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Collins, MO | 1 |
| Knight, CA | 1 |
| Deng, KM; Lin, Q; Lu, Y; Niu, YY; Yao, LY; Zhang, JH | 1 |
| Abe, H; Chi, H; He, W; Kitaoka, N; Kodama, H; Liu, G; Yamashita, K | 1 |
| Carvalheira, JB; Carvalho, HF; Clemente, CF; Dalla Costa, AP; Franchini, KG; Nadruz, W | 1 |
| Ahn, JH; Batra, S; Cram, EJ; Lee, M; Tam, P; Xu, X; Yu, EJ | 1 |
| de la Monte, S; He, J; Wands, JR | 1 |
| Bahnson, BJ; Colman, RF; Thévenin, AF; Zony, CL | 1 |
| Foster, SA; Morgan, DO; Rodrigo-Brenni, MC | 1 |
| Rhee, SG; Woo, HA | 1 |
| Ding, G; Geistlinger, L; Li, H; Li, Y; Liu, L; Tateno, Y; Wang, Z; Zeng, R | 1 |
| Azad, A; Edelmann, MJ; Fox, JL; Ismail, F; Jackson, S; Kessler, BM; Leigh, IM; Leverrier, S; Storey, A; Ternette, N | 1 |
| Chica, C; Diella, F; Dinkel, H; Gibson, TJ; Gould, CM; Jensen, LJ; Via, A | 1 |
| Igarashi, J; Kobayashi, N; Matsushita, M; Sasaki, T; Shimizu, T; Yoshioka, S | 1 |
| Gray, VE; Kumar, S | 1 |
| Chikamori, K; Ganapathi, MK; Ganapathi, R; Grozav, AG; Kinter, M; Kozuki, T; Micluta, MA; Petrescu, AJ; Willard, BB | 1 |
| Al-Eryani, R; Ball, HL; Li, Y; Orth, K; Yarbrough, ML | 1 |
| Black, SM; Darragh, C; Elms, S; Fonseca, FV; Fulton, D; Kumar, S; Pardo, D; Rafikov, R | 1 |
| Cho, S; Kim, HJ; Kim, SJ; Lee, DH; Lee, JA; Park, BC; Park, JE; Park, SG; Uchida, C; Uchida, T | 1 |
| Blennow, K; Brinkmalm, G; Halim, A; Larson, G; Nilsson, J; Portelius, E; Rüetschi, U; Westman-Brinkmalm, A; Zetterberg, H | 1 |
| Danko, J; Horton, K; Kostyal, D; Lanning, C; Shay, T; Welt, RS; Welt, S | 1 |
| Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W | 1 |
| Henderson, JM; Kraus, M; Otipoby, KL; Patterson, HC; Rajewsky, K; Seagal, J; Shahsafaei, A; Thai, TH; Wang, D | 1 |
| Chen, XP; Cui, L; Hoi, PM; Tan, W; Wang, YT; Wu, GS; Wu, T; Xu, ZT; Zhong, ZF | 1 |
| Chou, KC; He, ZS; Kong, XY; Shi, XH; Zhu, YB | 1 |
| Aké, F; Deutscher, J; Henry, C; Mijakovic, I; Milohanic, E; Misra, SK; Monnet, V | 1 |
| Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH | 1 |
| Jensen, ON; Manteca, A; Sánchez, J; Ye, J | 1 |
| Chen, JH; Huang, ZR; Liu, HY; Zhu, SJ | 1 |
| English, RD; Kurosky, A; Wiktorowicz, JE; Wu, Z | 1 |
| Edimo, WE; Erneux, C; Janssens, V; Waelkens, E | 1 |
| Blough, ER; Kakarla, SK; Katta, A; Kolli, MB; Kundla, S; Manne, ND; Nalabotu, SK; Wu, M | 1 |
| Eick, D; Heidemann, M | 1 |
| Kosten, J; Kriwacki, RW; Landrieu, I; Liokatis, S; Lippens, G; Selenko, P; Smet-Nocca, C; Theillet, FX; Thongwichian, R; Yoon, MK | 1 |
| Clouse, SD; Harper, JF; Huber, SC; Kim, HS; Oh, MH; Wu, X; Zielinski, RE | 1 |
| Huang, Q; Ruan, ZR; Tan, M; Wang, ED; Zhou, XL | 1 |
| Benda, L; Boelens, R; Emmer, J; Koča, J; Kříž, Z; Sklenář, V; Sychrovský, V; Trantírek, L; Vavrinská, A | 1 |
| Chen, W; Dudek, SM; Ephstein, Y; Garcia, JG; Jacobson, JR; Kanteti, P; Salgia, R; Singleton, PA; Wang, L | 1 |
| Bansal, N; Berezney, R; Bhaskar, A; Fritz, A; Itotia, P; Lam, TT; Lee, E; Lyubchenko, YL; Shlyakhtenko, LS; Stafford, WF; Thapar, R; Zhang, M | 1 |
| Albers, MF; Hedberg, C | 1 |
| Ge, F; Li, T; Qiao, ZX; Xiong, Q; Yang, MK; Zhang, J; Zhang, WY; Zhao, JD | 1 |
| Camerini, S; Crescenzi, M; Gatti, V; Siepi, F; Soddu, S | 1 |
| Gela, D; Hulak, M; Li, P; Li, ZH; Linhart, O; Psenicka, M; Rodina, M; Sulc, M | 1 |
| D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J | 1 |
| Bamberg-Lemper, S; Becker, W; Birner-Gruenberger, R; Bracher, F; Hilz, N; Preisinger, C; Rüben, K; Walte, A | 1 |
| Sakurai, H; Tanaka, T; Zhou, Y | 1 |
| Chen, L; Liu, S; Shi, F; Su, X | 1 |
| Asif, AR; Herlyn, H; Ramljak, S; Schaffrath, M; Schumacher, J; Zischler, H | 1 |
| Brown, NR; Cong, F; Diehl, BG; Hill, JL; Tien, M | 1 |
| Mu, XY; Qi, L; Qiao, J; Sun, BB; Wang, ML | 1 |
| Kim, JY; Kwon, OK; Lee, S; Sim, J; Yun, KN | 1 |
| Ko, HL; Liu, J; Ren, EC; Shen, M; Xiao, Z | 1 |
| Mayle, S; Monie, TP | 1 |
| Chari, A; Daub, H; Draeger-Meurer, S; Fischer, U; Gruss, OJ; Husedzinovic, A; Oppermann, F | 1 |
| Cherella, C; Copps, KD; Hançer, NJ; Li, Y; Qiu, W; White, MF | 1 |
| Aranda, J; Bou, G; Méndez, JA; Nakedi, K; Soares, NC; Spät, P | 1 |
| Choe, D; Jang, H; Shin, CS | 1 |
| Grundner, C; Sherman, DR | 1 |
| Cox, J; D'Souza, RC; Mann, M; Schaab, C; Sharma, K; Tyanova, S; Wiśniewski, JR | 1 |
| Calleja, V; de Las Heras-Martinez, G; Laguerre, M; Larijani, B; Parker, PJ; Requejo-Isidro, J | 1 |
| Archambaud, C; Cao, TN; Cossart, P; Deutscher, J; Henry, C; Milohanic, E; Misra, SK; Monnet, V; Moussan Désirée Aké, F; Wu, Z | 1 |
| Hedberg, C; Itzen, A | 1 |
| Huang, SY; Liu, MC; Qiu, JD; Shi, SP | 1 |
| Gray, MA; James Squires, E | 1 |
| Bánhegyi, G; Bögre, L; Darula, Z; Horváth, GV; Kállai, BM; Medzihradszky, KF; Mészáros, T; Nagy, SK | 1 |
| Burmeister, BT; Carnegie, GK; Gold, MG; O'Bryan, JP; Skidgel, RA; Wang, L | 1 |
| Schulze, WX; Xu, D; Yao, Q | 1 |
| Bian, Y; Cheng, K; Wang, F; Ye, M; Zou, H | 1 |
| Ağar, G; Anar, M; Öğütçü, H; Özkan, EH; Şakıyan, İ; Sarı, N | 1 |
| Anastasiadis, PZ; Copland, JA; Huveldt, D; Kourtidis, A; Yanagisawa, M | 1 |
| Kirken, RA; Ross, JA; Ruiz-Medina, BE | 1 |
| Cesaro, L; Pinna, LA | 1 |
| Derouiche, A; Kalantari, A; Mijakovic, I; Shi, L | 1 |
| Besong Agbo, D; Klafki, H; Kraus, I; Otto, M; Wiltfang, J | 1 |
| Barnett, BL; Dunford, JE; Ebetino, FH; Evdokimov, A; Kavanagh, KL; Kwaasi, AA; Muniz, JR; Oppermann, U; Pilka, ES; Russell, RGG; Tsoumpra, MK; Von Delft, F; Walter, RL | 1 |
| Ramaiah, KVA; Swetha, M | 1 |
| Arnold, E; Boyer, PL; Das, K; Hughes, SH | 1 |
| Chen, WX; Liu, T; Tian, CF | 1 |
| Kim, D; Ntui, VO; Xiong, L; Zhang, N | 1 |
| Alfonso, I; Faggi, E; Luis, SV; Vicent, C | 1 |
| Dautel, R; Harter, K; Heunemann, M; Schulze, WX; Wu, XN | 1 |
| Johnstone, SR; Lohman, AW; Straub, AC | 1 |
| Li, B; Ling, C; Ma, W; Srivastava, A | 1 |
| Armutlulu, A; Balaram, H; Balasubramanian, S; Bartosh, TJ; Broda, M; Brown, LE; Burroughs, LM; Burrows, F; Cardoso, JR; Carregaro, RL; Cho, J; Cui, Q; Dela Bela, LF; Dias, JM; Dutta, NK; Flowers, ME; Gallo, S; Hari, P; He, R; He, Y; Heimfeld, S; Jia, B; Jin, X; Jin, YJ; Karakousis, PC; Karmakar, T; Kiem, HP; Kreager, DA; Lebedev, D; Li, F; Li, S; Liang, N; Liu, Z; Luo, J; Luo, Y; Mazuquin, BF; Meng, Y; Mosialos, G; Moura, FA; Müller, CR; Naeem, MA; Nagappa, LK; Nguyen, H; Pelegrinelli, AR; Pinn, ML; Prahlada Rao, VS; Pulsipher, MA; Ragan, DT; Richards, J; Roy, S; Sandmaier, BM; Selfe, J; Selim, MA; Shi, J; Shi, X; Staff, J; Storb, R; Storer, BE; Wang, F; Wang, M; Wang, S; Woolfrey, AE; Wright, T; Ylostalo, JH; Zhang, JY; Zhang, ZY; Zheng, K; Zhu, Z | 1 |
| Desaki, Y; Fujimoto, Z; Ishibashi, Y; Kaku, H; Kito, K; Matsui, S; Motoyama, N; Nakashima, M; Ohnishi, M; Shibuya, M; Shibuya, N; Shimada, H; Suto, K; Suzuki, M; Takahashi, S; Tsujimoto, N; Yoshida, I | 1 |
| Andreeva, S; Buvall, L; Choi, HY; Greka, A; Mundel, P; Sieber, J; Wallentin, H | 1 |
| Carney, EF | 1 |
| Kol, S; Montefiori, M; Motawia, MS; Møller, BL; Nørholm, MH; Olsen, L; Vazquez-Albacete, D | 1 |
| Fiedler, D; Marmelstein, AM; Moreno, J | 1 |
| Jasnovidova, O; Krejcikova, M; Kubicek, K; Stefl, R | 1 |
| Armstrong, D; Bancerz, M; Cabral, AD; de Araujo, ED; Duodu, E; Fekl, U; Fong, R; Gardiner, JE; Gunning, PT; Kraskouskaya, D; Rosa, D; Toutah, K | 1 |
| Ahmad, S; Hasan, MAM; Molla, MKI | 1 |
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| Bai, Y; Chen, B; Chen, M; Li, M; Ren, S; Wang, S; Xu, Q; Zhou, Y | 1 |
| Li, BQ; Li, SY; Liu, JJ; Wang, X; Xu, ML; Zhai, HL | 1 |
| Al-Bossier, AS; Alanazi, YH; Alduayji, MA; Alghidani, BA; Alkharraz, OS; Alnasser, NA; Alobaid, AS; Alsaif, AK; Alsuhaibani, SA; Altorbag, AA; Altuwayjiri, KM; Bu Mozah, AA; Rasheed, Z | 1 |
| Boveris, A; Buchholz, B; Gelpi, RJ; Helfenberger, KE; Poderoso, C; Poderoso, JJ; Villalba, NM | 1 |
| An, JU; Hong, SH; Oh, DK | 1 |
| Attems, J; Daum, G; Flunkert, S; Hoeller, C; Hutter-Paier, B; Kerschbaumer, B; Loeffler, T; Neddens, J; Niederkofler, V; Temmel, M | 1 |
| Corin, K; Entzian, C; Kubicek, J; Kwon, Y; Labahn, J; Maertens, B; Qing, R; Schubert, T; Skuhersky, M; Suter, B; Tang, H; Tao, F; Tegler, L; Wassie, A; Wassie, B; Yang, G; Zhang, S | 1 |
| Jurásková, V; Vondrášek, J; Vymětal, J | 1 |
| Felekyan, S; Hemmen, K; Iconaru, L; Kriwacki, R; Park, CG; Phillips, AH; Sanabria, H; Seidel, CAM; Tompa, P; Tsytlonok, M; Vaithiyalingam, S; Waddell, MB; Wang, Y; White, SW; Yun, MK | 1 |
| Limpikirati, P; Pan, X; Vachet, RW | 1 |
| Kang, GY; Kim, KP; Lee, JW; Lee, N; Park, SH | 1 |
| Hassan, A; Maiti, S; Mitra, P | 1 |
| Forman-Kay, JD; Kay, LE; Kim, TH; Sonenberg, N; Tsang, B; Vernon, RM | 1 |
| Assar, Z; Borhan, B; Esmatpour Salmani, R; Geiger, JH; Ghanbarpour, A; Jin, X; Nosrati, M; Pawlowski, K; Pinger, C; Santos, EM; Spence, D; Vasileiou, C | 1 |
| Boomsma, W; Bugge, K; Fernandes, CB; Hendus-Altenburger, R; Kragelund, BB; Kunze, MBA | 1 |
| Ano, Y; Kondo, K; Ohya, R | 1 |
| Ano, Y; Ayabe, T; Ohya, R | 1 |
| Alqhazo, M; Rashaid, AB | 1 |
| Chi, A; Yan, J; Yao, C; Zhao, S | 1 |
| Bonne Køhler, J; Derouiche, A; Jers, C; Mijakovic, I; Senissar, M; Shi, L | 1 |
| Hinton, SD | 1 |
| Al-Sha'er, MA; Taha, MO | 1 |
| Machuqueiro, M; Oliveira, NFB; Pires, IDS | 1 |
| Blum, Z; Robertsson, C; Svensäter, G; Wickström, C | 1 |
| Ahmed, S; Arif, M; Kabir, M; Khan, ZU; Yu, DJ | 1 |
| Alain, T; Anton, L; Berman, AJ; Celucci, G; Chaker-Margot, M; Dajadian, C; Damgaard, CK; Fonseca, BD; Graber, TE; Hearnden, J; Hoang, HD; Hollensen, AK; Jia, JJ; Lahr, RM; Livingstone, M; Maier, T; Moraes, BJ; Niklaus, MR; Pena, IA; Pointet, R; Smith, EM; Solgaard, MT; Wang, XD; Yang, AD; Yu, Y | 1 |
| González-Rubio, G; Martín, H; Molina, M; Sellers-Moya, Á | 1 |
| Bazer, FW; Herring, CM; Wu, G | 1 |
| Hu, Y; Jiang, B; Zhang, L; Zhang, Y | 1 |
| He, W; Li, P; Wu, G | 1 |
| Doubleday, PF; Gruber, CH; Johns, NI; Krishnan, A; Park, J; Raguz Nakic, Z; Sauer, U; Schastnaya, E; Wang, HH | 1 |
| Li, M; Liu, Y; Lu, W; Na, B; Qin, H; Qing, G; Tang, M; Wang, D; Xiong, Y | 1 |
| Cao, LQ; Gao, YH; Qu, SS; Yao, M | 1 |
| Kirsch, ZJ; Tremblay, CY; Vachet, RW | 1 |
| Cordo', V; de Ru, AH; Friggen, AH; Hensbergen, PJ; Mohammed, Y; Smits, WK; van Veelen, PA | 1 |
| Ding, Y; Liu, C; Ren, L; Shen, D | 1 |
| Li, Y; Ping, Q; Wang, S | 1 |
| Buchser, WJ; Hinton, SD; Kelley, K; Kuang, D; Qi, Y | 1 |
| Huang, R; Li, S; Miao, X; Xiao, B; Yang, J | 1 |
| Anjum Zia, M; Jahan, N; Kiran, S; Mujtaba, N; Naqvi, SAR; Sultana, B | 1 |
| Hu, L; Li, J; Ma, Z; Song, W; Yang, L | 1 |
| Ji, X; Jiang, P; Li, Y; Yan, W; Yue, H | 1 |
| Anwar, S; Hasan, GM; Hassan, MI; Islam, A; Shahwan, M | 1 |
| Christodoulou, C; Mavrommatis, A; Prandi, B; Righi, F; Sforza, S; Simoni, M; Tedeschi, T; Tsiplakou, E | 1 |
| Cheng, Y; Guo, Y; Jiang, W; Liu, C; Qian, H; Yang, F; Yao, W; Zhao, Y | 1 |
| Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
| Agorreta, J; Amat, R; Bértolo, C; Bosco, G; Calvo, A; Echepare, M; Felip, E; Frigola, J; López-Picazo, JM; Melero, I; Montuenga, LM; Pasquier, A; Picabea, B; Sainz, C; Tamayo, I; Teijeira, Á; Thomas, R; Valencia, K | 1 |
| Cao, L; Chen, X; Han, Y; Jin, Y; Lv, Y; Qu, X; Zhang, J; Zhang, Y | 1 |
| Araki, E; Cai, W; Fukuda, K; Fukuda, T; Igata, M; Kahn, CR; Kondo, T; Okagawa, S; Okubo, Y; Otsuka, Y; Sakaguchi, M; Sakaguchi, N; Sato, Y; Tseng, YH; Yamagata, K; Yoshizawa, T | 1 |
| Abdel Rahman, AM; Al-Ansari, MM; Alabdaljabar, MS; Dahabiyeh, LA; Housien, M; Jacob, M; Nimer, RM; Sabi, EM; Sumaily, KM | 1 |
| Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X | 1 |
| Lin, X; Tu, H; Xiong, W; Zhang, J; Zhao, X | 1 |
| Ayati, M; Bermea, KC; Everett, AD; Foster, DB; Fu, Z; Gabrielson, K; Heravi, A; Kim, HB; Medina, A; Murphy, AM; Na, CH; Paolocci, N; Ramirez-Correa, GA; Xu, M; Yang, X; Zhang, X | 1 |
| Gizzio, J; Haldane, A; Levy, RM; Thakur, A | 1 |
| An, J; Jia, X; Li, X; Liu, R; Liu, S; Mo, Y; Wei, X; Zhang, S; Zhang, Y; Zhou, L | 1 |
| Brzozowski, JS; Dun, MD; Humphrey, SJ; Kahl, RGS; Miller, K; Murray, HC; Smith, ND; Verrills, NM | 1 |
| Bilmez, Y; Can, A; Kosebent, EG; Ozturk, S; Talibova, G; Tire, B | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Che, L; Fang, Z; Feng, B; Hua, L; Jiang, X; Li, J; Lin, Y; Sun, M; Wang, Y; Xu, S; Zhuo, Y; Zou, X | 1 |
| Cao, Y; Luo, Z; Ma, Y; Shan, J; Song, X; Xu, W; Zhou, J | 1 |
| Albillos, A; Arribas, RL; Jiménez-Pompa, A; McIntosh, JM | 1 |
| Khalid, A; O'Brien-Simpson, NM; Pyreddy, S; Qazi, F; Redmond, CE; Shukla, R; Tomljenovic-Hanic, S; Verma, R | 1 |
45 review(s) available for tyrosine and threonine
| Article | Year |
|---|---|
The role of Raf-1 phosphorylation in signal transduction.
Topics: Amino Acid Sequence; Animals; Cell Division; Enzyme Activation; Growth Substances; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Cell Surface; Serine; Signal Transduction; Substrate Specificity; Threonine; Tyrosine | 1992 |
Tyrosine phosphatases and their possible interplay with tyrosine kinases.
Topics: Animals; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1992 |
Dual-specificity protein kinases: will any hydroxyl do?
Topics: Amino Acid Sequence; Animals; Humans; Hydroxylation; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Serine; Substrate Specificity; Threonine; Tyrosine | 1992 |
Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation.
Topics: Amino Acid Sequence; Molecular Sequence Data; Phosphorylation; Protein Kinases; Serine; Signal Transduction; Threonine; Tyrosine | 1992 |
ERKs, extracellular signal-regulated MAP-2 kinases.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Extracellular Space; Glycogen Synthase Kinase 3; Growth Substances; Hormones; Models, Biological; Phosphorylation; Protein Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Threonine; Tyrosine | 1991 |
Protein-tyrosine kinases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Epidermal Growth Factor; ErbB Receptors; Humans; Lipid Metabolism; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Cell Surface; Retroviridae; Serine; Substrate Specificity; Threonine; Tyrosine; Viral Proteins | 1985 |
Insulin receptor kinase and its mode of signaling membrane components.
Topics: Animals; Enzyme Activation; ErbB Receptors; Humans; Insulin; Kinetics; Monosaccharide Transport Proteins; Phospholipids; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Serine; Threonine; Tyrosine | 1985 |
Epidermal growth factor and its receptor.
Topics: Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Gene Amplification; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogenes; Threonine; Tyrosine | 1987 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
Microbial production of amino acids.
Topics: Amino Acids; Bacteria; Biotin; Chemical Industry; Glutamates; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[Chemical cleavage of peptide bonds].
Topics: Amino Acids; Chemical Phenomena; Chemistry; Histidine; Methionine; Peptides; Proline; Serine; Threonine; Tryptophan; Tyrosine | 1968 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
Effects of ingestion of disproportionate amounts of amino acids.
Topics: Adaptation, Physiological; Age Factors; Amino Acids; Ammonia; Animals; Cystine; Deficiency Diseases; Feeding Behavior; Glycine; Growth Disorders; Histidine; Homeostasis; Humans; Leucine; Liver; Lysine; Methionine; Nicotinic Acids; Nutrition Disorders; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine | 1970 |
Diet, neurotransmitters and brain function.
Topics: Behavior; Brain; Choline; Diet; Energy Metabolism; Histidine; Humans; Minerals; Neurotransmitter Agents; Threonine; Tryptophan; Tyrosine; Vitamins | 1981 |
[The insulin receptor: an autonomous system for membrane transmission of the hormonal message].
Topics: Adenosine Triphosphate; Animals; Cell Membrane; Insulin; Liver; Molecular Weight; Phosphorylation; Protein Kinases; Receptor, Insulin; Serine; Threonine; Tyrosine | 1984 |
Amino acid degradation by anaerobic bacteria.
Topics: Amino Acids; Anaerobiosis; Aspartic Acid; Clostridium; Culture Media; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Species Specificity; Threonine; Tryptophan; Tyrosine; Valine | 1981 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Insulin and IGF-1 signaling in oocyte maturation.
Topics: Animals; Cellular Senescence; Genes, ras; Humans; Insulin; Insulin-Like Growth Factor I; Oocytes; Phosphorylation; Serine; Signal Transduction; Threonine; Tyrosine | 1994 |
NMR, alcohols, protein solvation and protein denaturation.
Topics: Alcohols; Magnetic Resonance Spectroscopy; Protein Conformation; Protein Denaturation; Proteins; Serine; Solvents; Threonine; Tyrosine | 1994 |
Protein phosphatases.
Topics: Humans; Models, Molecular; Phosphoprotein Phosphatases; Phosphorylation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Serine; src Homology Domains; Substrate Specificity; Threonine; Tyrosine | 1995 |
Regulation of potassium channels by protein kinases.
Topics: Animals; Cell Membrane; Enzyme Activation; Humans; Kinetics; Phosphorylation; Potassium Channels; Protein Kinases; Serine; Threonine; Tyrosine | 1996 |
Myt1: a Wee1-type kinase that phosphorylates Cdc2 on residue Thr14.
Topics: Amino Acid Sequence; Animals; Binding Sites; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; G2 Phase; Humans; Membrane Proteins; Mitosis; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Schizosaccharomyces pombe Proteins; Substrate Specificity; Threonine; Tyrosine | 1997 |
Epstein-Barr virus latency: LMP2, a regulator or means for Epstein-Barr virus persistence?
Topics: Adolescent; Amino Acid Motifs; Amino Acid Sequence; Animals; B-Lymphocytes; Cell Line, Transformed; Cell Transformation, Viral; Epithelial Cells; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Phosphorylation; Point Mutation; Proline; Protein Conformation; Protein Processing, Post-Translational; Sequence Deletion; Serine; Signal Transduction; src Homology Domains; Threonine; Tumor Virus Infections; Tyrosine; Viral Matrix Proteins; Virus Latency | 2000 |
Cortactin: coupling membrane dynamics to cortical actin assembly.
Topics: Actins; Animals; Cortactin; Humans; Microfilament Proteins; Models, Biological; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine; Tyrosine | 2001 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
Activating p38 MAPK: new tricks for an old kinase.
Topics: Amino Acid Motifs; Animals; Enzyme Activation; Humans; MAP Kinase Signaling System; Models, Biological; Models, Molecular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Conformation; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Threonine; Tyrosine | 2005 |
Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones.
Topics: Animals; Antioxidants; Catalysis; Cysteine; Disulfides; Humans; Hydrogen Peroxide; Kinetics; Molecular Chaperones; Oxidation-Reduction; Peroxides; Peroxiredoxins; Phosphorylation; Threonine; Tyrosine | 2011 |
eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity.
Topics: Amino Acid Sequence; Animals; Biopterins; Cell Membrane; Dimerization; Enzyme Activation; Humans; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Quaternary; Serine; Threonine; Tyrosine | 2011 |
Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code.
Topics: Animals; Humans; Phosphorylation; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; RNA Polymerase II; Threonine; Transcription, Genetic; Tyrosine | 2012 |
[Regulation of receptor tyrosine kinases by Ser/Thr phosphorylation].
Topics: Animals; Humans; Molecular Targeted Therapy; Phosphorylation; Receptor Protein-Tyrosine Kinases; Signal Transduction; Threonine; Tyrosine | 2013 |
Agents of change - concepts in Mycobacterium tuberculosis Ser/Thr/Tyr phosphosignalling.
Topics: Gene Expression Regulation, Bacterial; Mycobacterium tuberculosis; Phosphorylation; Protein Kinases; Serine; Signal Transduction; Threonine; Tyrosine | 2014 |
Acute regulation of PDK1 by a complex interplay of molecular switches.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Dimerization; Enzyme Activation; Humans; Ligands; Models, Molecular; Neoplasm Proteins; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Protein Transport; Serine; Signal Transduction; Threonine; Tyrosine | 2014 |
Molecular perspectives on protein adenylylation.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bacteria; Bacterial Infections; Enzymes; Humans; Mass Spectrometry; Models, Molecular; Protein Conformation; Protein Processing, Post-Translational; Threonine; Tyrosine | 2015 |
The generation of phosphoserine stretches in phosphoproteins: mechanism and significance.
Topics: Casein Kinase I; Casein Kinase II; Glycogen Synthase Kinase 3; Humans; Phosphoproteins; Phosphoserine; Threonine; Tyrosine | 2015 |
Serine/threonine/tyrosine phosphorylation regulates DNA binding of bacterial transcriptional regulators.
Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Histidine Kinase; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2015 |
Chemical Approaches to Studying Labile Amino Acid Phosphorylation.
Topics: Amino Acids; Humans; Phosphorylation; Proteins; Serine; Threonine; Tyrosine | 2017 |
The RNA polymerase II CTD "orphan" residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7.
Topics: Humans; RNA Polymerase II; Serine; Threonine; Transcription, Genetic; Tyrosine | 2018 |
Importance of protein Ser/Thr/Tyr phosphorylation for bacterial pathogenesis.
Topics: Animals; Bacteria; Bacterial Infections; Bacterial Proteins; Humans; Phosphoproteins; Phosphorylation; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2020 |
Pseudophosphatase MK-STYX: the atypical member of the MAP kinase phosphatases.
Topics: Animals; Humans; Mitogen-Activated Protein Kinase Phosphatases; Phosphoserine; Threonine; Tyrosine | 2020 |
[Advancesin enrichment and detection methods for
Topics: Arginine; Histidine; Lysine; Phosphorylation; Proteins; Serine; Threonine; Tyrosine | 2020 |
Protein Tyrosine and Serine/Threonine Phosphorylation in Oral Bacterial Dysbiosis and Bacteria-Host Interaction.
Topics: Dental Caries; Dysbiosis; Host Microbial Interactions; Humans; Microbiota; Phosphorylation; Porphyromonas gingivalis; Serine; Threonine; Tyrosine | 2021 |
Importance of Tyrosine Phosphorylation in Hormone-Regulated Plant Growth and Development.
Topics: Animals; Biological Phenomena; Hormones; Phosphorylation; Plant Development; Plant Growth Regulators; Plants; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2022 |
Microtubule-affinity regulating kinase 4: A potential drug target for cancer therapy.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Humans; Microtubules; Neoplasms; Neurodegenerative Diseases; NF-kappa B; Phosphates; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Serine; Threonine; TOR Serine-Threonine Kinases; Tyrosine | 2022 |
2 trial(s) available for tyrosine and threonine
| Article | Year |
|---|---|
Plasma amino acid concentrations, indexes of protein metabolism and growth in healthy, full-term infants fed partially hydrolyzed infant formula.
Topics: Amino Acids; Birth Weight; Gestational Age; Growth; Humans; Hydrolysis; Infant Food; Infant, Newborn; Nutritive Value; Ornithine; Proteins; Serum Albumin; Threonine; Tyrosine | 1998 |
The pattern of intracellular free amino acids in granulocytes from hemodialysis patients change to an oral protein supplement (granulocyte amino acids after protein in HD patients).
Topics: Adult; Aged; Amino Acids; Anthropometry; Blood Proteins; Cross-Over Studies; Dietary Proteins; Dietary Supplements; Double-Blind Method; Electric Impedance; Female; Glycine; Granulocytes; Humans; Isoleucine; Male; Middle Aged; Nitrogen; Phenylalanine; Placebos; Renal Dialysis; Somatomedins; Threonine; Tyrosine; Valine | 1999 |
764 other study(ies) available for tyrosine and threonine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Beneficial effect of methionine and threonine supplements on tyrosine toxicity in rats.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Animals; Body Weight; Caseins; Diet; Homogentisic Acid; Liver; Methionine; Oxygenases; Rats; Threonine; Tyrosine; Tyrosine Transaminase | 1976 |
Effect of dietary threonine supplementation on tyrosine toxicity in the rat.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Animals; Ascorbic Acid; Dietary Proteins; Dose-Response Relationship, Drug; Hydro-Lyases; Liver; Oxygenases; Phenylpyruvic Acids; Rats; Threonine; Threonine Dehydratase; Time Factors; Tyrosine; Tyrosine Transaminase | 1977 |
The free amino acid pool composition during growth of the culture of Xanthomonas citri (Hasse) Dowson.
Topics: Alanine; Amino Acids; Asparagine; Kinetics; Threonine; Tyrosine; Xanthomonas | 1979 |
Hemolysis and lysosomal activation by solid state tyrosine.
Topics: Animals; Bucladesine; Dialysis; Dose-Response Relationship, Drug; Erythrocytes; Glucose; Glucuronidase; Hemolysis; Humans; Liver; Lysosomes; Male; Phenylalanine; Propylene Glycols; Rats; Sucrose; Threonine; Tyramine; Tyrosine | 1975 |
Alteration of free serum amino acids in voles infected with Trypanosoma brucei gambiense.
Topics: Alanine; Amino Acids; Animals; Arvicolinae; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Male; Proline; Serine; Threonine; Trypanosomiasis, African; Tryptophan; Tyrosine; Valine | 1977 |
Side reactions in peptide synthesis. X. Prevention of O-acylation during coupling with active esters.
Topics: Acylation; Amino Acid Sequence; Dinitrophenols; Esters; Pentachlorophenol; Peptides; Serine; Threonine; Tyrosine | 1979 |
[Senile liver and its repercussions on cerebral activity].
Topics: Aged; Aging; Amino Acids; Brain; Cystine; Glutamates; Histidine; Humans; Liver; Serine; Threonine; Tyrosine | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
Specific sulfonation of tyrosine, tryptophan and hydroxy-amino acids in peptides.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Peptides; Protein Binding; Serine; Sulfonic Acids; Sulfuric Acids; Threonine; Tryptophan; Tyrosine | 1979 |
[Normal range of free amino acids in cerebrospinal fluid of children (author's transl)].
Topics: Adolescent; Age Factors; Amino Acids; Aspartic Acid; Child; Child, Preschool; Citrulline; Female; Histidine; Humans; Infant; Lysine; Male; Methods; Serine; Sex Factors; Threonine; Tyrosine | 1977 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein.
Topics: Adult; Aged; Amino Acids; Circadian Rhythm; Dietary Proteins; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis, Alcoholic; Male; Methionine; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Nitrogen balance in uremic patients on different amino acid and keto acid formulations--a proposed reference pattern.
Topics: Adolescent; Adult; Aged; Amino Acids; Child; Female; Histidine; Humans; Keto Acids; Male; Methionine; Middle Aged; Nitrogen; Nutritional Requirements; Threonine; Tyrosine; Uremia | 1978 |
The regulation of diaminopimelate decarboxylase activity in Escherichia coli strain w.
Topics: Aspartate Kinase; Carboxy-Lyases; Diaminopimelic Acid; Enzyme Repression; Escherichia coli; Lysine; Mutation; Phenylalanine; Pyridoxine; Stereoisomerism; Threonine; Tryptophan; Tyrosine | 1976 |
Azide-dependent mutants in E. coli K12.
Topics: Azides; Chromosome Mapping; Escherichia coli; Genes; Mutation; Operon; Phenylalanine; Threonine; Tryptophan; Tyrosine | 1976 |
The role of plasma amino acids in hepatic encephalopathy.
Topics: Albumins; Amino Acids; Ammonia; Animals; Arginine; Blood Urea Nitrogen; Dogs; Glucose; Glutamates; Hepatic Encephalopathy; Isoleucine; Leucine; Liver Function Tests; Methionine; Parenteral Nutrition; Phenylalanine; Portacaval Shunt, Surgical; Threonine; Tryptophan; Tyrosine; Valine | 1975 |
Route of administration and portal vein amino acid concentration.
Topics: Administration, Oral; Alanine; Amino Acids; Animals; Glycine; Injections, Intravenous; Liver; Parenteral Nutrition; Portal Vein; Rats; Threonine; Tyrosine | 1976 |
Variations in the concentrations of blood plasma free amino acids in suckled and fasted neonatal pigs.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Cystine; Fasting; Glycine; Leucine; Lysine; Proline; Serine; Swine; Threonine; Tyrosine | 1977 |
Effect of supplementation of limiting amino acids on tyrosine toxicity in rats fed wheat gluten diets.
Topics: Amino Acids; Animals; Food, Fortified; Glutens; Liver; Lysine; Male; Methionine; Muscles; Nutritional Requirements; Rats; Threonine; Triticum; Tyrosine | 1977 |
Lowering brain phenylalanine levels by giving other large neutral amino acids. A new experimental therapeutic approach to phenylketonuria.
Topics: Amino Acids; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Drug Combinations; Humans; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Effect of individual amino acid supplements on the toxicity of excess tyrosine in rats.
Topics: Amino Acids; Amino Acids, Essential; Animals; Body Weight; Cataract; Diet; Dietary Proteins; Male; Methionine; Rats; Threonine; Tyrosine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Hydration of amino acid side chains: dependence on secondary structure.
Topics: Amino Acids; Computer Simulation; Hydrogen Bonding; Mathematical Computing; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Serine; Software; Threonine; Tyrosine; Water | 1992 |
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Rabbits; Rats; Serine; Signal Transduction; Threonine; Tyrosine | 1992 |
A purified S6 kinase kinase from Xenopus eggs activates S6 kinase II and autophosphorylates on serine, threonine, and tyrosine residues.
Topics: Animals; Caseins; Cell Line; Chromatography, Gel; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Histones; Isoenzymes; Phosphoric Monoester Hydrolases; Phosphorylation; Phosvitin; Protamines; Protein Kinase Inhibitors; Protein Kinases; Ribosomal Protein S6 Kinases; Serine; Substrate Specificity; Threonine; Tyrosine; Xenopus | 1992 |
Growth factor-induced activation of a kinase activity which causes regulatory phosphorylation of p42/microtubule-associated protein kinase.
Topics: 3T3 Cells; Amino Acid Sequence; Amino Acids; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Epidermal Growth Factor; Humans; Kinetics; Mice; Mutagenesis, Site-Directed; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Threonine; Tyrosine | 1992 |
Activation of mitogen-activated protein (MAP) kinase by a MAP kinase-kinase.
Topics: Adenosine; Autoradiography; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1992 |
Involvement of MAP kinase activators in angiotensin II-induced activation of MAP kinases in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinases; Rats; Serine; Threonine; Tyrosine | 1992 |
Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15.
Topics: Amino Acid Sequence; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; Fungal Proteins; HeLa Cells; Homeostasis; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphates; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; ras-GRF1; Sequence Homology, Amino Acid; Threonine; Tyrosine | 1992 |
Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cell Cycle; CHO Cells; Cricetinae; Enzyme Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Nocodazole; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Threonine; Thymidine; Tyrosine | 1992 |
Novel protein kinase of Arabidopsis thaliana (APK1) that phosphorylates tyrosine, serine and threonine.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Base Sequence; Blotting, Southern; Cloning, Molecular; DNA; Escherichia coli; Humans; Immunoblotting; Molecular Sequence Data; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Serine; Threonine; Tyrosine | 1992 |
Role of conserved threonine and tyrosine residues in acetylcholine binding and muscarinic receptor activation. A study with m3 muscarinic receptor point mutants.
Topics: Acetylcholine; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Guanylyl Imidodiphosphate; In Vitro Techniques; Inositol Phosphates; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Muscarinic; Signal Transduction; Structure-Activity Relationship; Threonine; Tyrosine | 1992 |
The comparative efficiencies of the Ser(P)-, Thr(P)- and Tyr(P)-residues as specificity determinants for casein kinase-1.
Topics: Amino Acid Sequence; Casein Kinases; Indicators and Reagents; Kinetics; Molecular Sequence Data; Oligopeptides; Protein Kinases; Serine; Substrate Specificity; Threonine; Tyrosine | 1992 |
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells.
Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins | 1992 |
Introduction of hydroxyl-bearing amino acids causes bathochromic spectral shifts in rhodopsin. Amino acid substitutions responsible for red-green color pigment spectral tuning.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line; Humans; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Restriction Mapping; Rhodopsin; Serine; Spectrophotometry; Threonine; Transfection; Tyrosine | 1992 |
Interaction of the N-terminal region of hirudin with the active-site cleft of thrombin.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Hirudins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Threonine; Thrombin; Tyrosine; Valine | 1992 |
Ordered phosphorylation of p42mapk by MAP kinase kinase.
Topics: Animals; Autoradiography; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Muscles; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rabbits; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 1992 |
Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.
Topics: Alleles; Amino Acid Sequence; Base Sequence; DNA, Fungal; Enzyme Activation; Fungal Proteins; Immunoblotting; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Pheromones; Phosphorylation; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Threonine; Tyrosine | 1992 |
DIDS-effect on Ser/Thr- and Tyr-phosphorylation of membrane proteins in human erythrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anion Exchange Protein 1, Erythrocyte; Binding Sites; Erythrocyte Membrane; Humans; In Vitro Techniques; Membrane Proteins; Phosphorylation; Serine; Spectrin; Threonine; Tyrosine | 1992 |
pp54 microtubule-associated protein-2 kinase requires both tyrosine and serine/threonine phosphorylation for activity.
Topics: Animals; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Kinase Inhibitors; Protein Kinases; Protein Phosphatase 1; Rabbits; Rats; Serine; Threonine; Tyrosine | 1991 |
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates.
Topics: Amino Acid Sequence; Animals; CDC2 Protein Kinase; Chickens; DNA; Enzyme Activation; Fluorescent Antibody Technique; HeLa Cells; Humans; Mitosis; Molecular Sequence Data; Mutation; Phenotype; Phosphorylation; Plasmids; Precipitin Tests; Protamine Kinase; Threonine; Transfection; Tyrosine | 1991 |
Site-directed mutagenesis of the m3 muscarinic receptor: identification of a series of threonine and tyrosine residues involved in agonist but not antagonist binding.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; Carbachol; Cell Line; Hydrolysis; Ligands; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Phosphatidylinositols; Plasmids; Rats; Receptors, Muscarinic; Threonine; Tyrosine | 1991 |
Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glycogen Synthase Kinase 3; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphorylation; Precipitin Tests; Protein Kinases; Swine; Tetradecanoylphorbol Acetate; Threonine; Trypsin; Tyrosine | 1991 |
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1990 |
Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody.
Topics: Antibodies, Monoclonal; Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Half-Life; Methylamines; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Determination of dityrosine, phosphotyrosine, phosphothreonine, and phosphoserine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Microchemistry; p-Dimethylaminoazobenzene; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Serine; Threonine; Tyrosine | 1990 |
[Phosphoamino acid analysis by 2-dimensional electrophoresis].
Topics: Electrophoresis, Gel, Two-Dimensional; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1990 |
In vivo phosphorylation and membrane association of the fyn proto-oncogene product in IM-9 human lymphoblasts.
Topics: Antibodies, Monoclonal; Membrane Proteins; Phosphorylation; Precipitin Tests; Protein Conformation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins pp60(c-src); Threonine; Tyrosine | 1990 |
The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Mutagenesis; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Sequence Homology, Nucleic Acid; Serine; Structure-Activity Relationship; Subcellular Fractions; Threonine; Tyrosine | 1991 |
Heparin stimulates epidermal growth factor receptor-mediated phosphorylation of tyrosine and threonine residues.
Topics: Amino Acids; Animals; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Escherichia coli; Glutathione Transferase; Heparin; Humans; Insecta; Manganese; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 1991 |
Signal transduction in human B cells during aging: alterations in stimulus-induced phosphorylations of tyrosine and serine/threonine substrates and in cytosolic calcium responsiveness.
Topics: Aging; Amino Acids; B-Lymphocytes; Calcium; Cell Division; Cells, Cultured; Cytosol; Humans; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Ribonucleases; Serine; Signal Transduction; Threonine; Tyrosine | 1991 |
Changes in insulin-receptor tyrosine, serine and threonine phosphorylation as a result of substitution of tyrosine-1162 with phenylalanine.
Topics: Amino Acid Sequence; Animals; Cell Line; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine; Transfection; Trypsin; Tyrosine | 1991 |
Insulin-EGF receptor chimerae mediate tyrosine transphosphorylation and serine/threonine phosphorylation of kinase-deficient EGF receptors.
Topics: ErbB Receptors; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Serine; Threonine; Tyrosine | 1991 |
Constitutive phosphorylation of the epidermal growth factor receptor blocks mitogenic signal transduction.
Topics: Animals; Autoradiography; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Enzyme Activation; ErbB Receptors; Mitogens; Mutation; Phosphorylation; Plasmids; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1991 |
Spk1, a new kinase from Saccharomyces cerevisiae, phosphorylates proteins on serine, threonine, and tyrosine.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Cycle Proteins; Checkpoint Kinase 2; Cloning, Molecular; Escherichia coli; Fungal Proteins; Gene Library; Genes, Fungal; Immunoblotting; Molecular Sequence Data; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Nucleic Acid; Serine; Substrate Specificity; Threonine; Tyrosine | 1991 |
Soluble HLA-A2.1 restricted peptides that are recognized by influenza virus specific cytotoxic T lymphocytes.
Topics: Amino Acid Sequence; HLA-A2 Antigen; Humans; Influenza A virus; Peptide Fragments; Solubility; T-Lymphocytes, Cytotoxic; Threonine; Tyrosine | 1991 |
Identification and characterization of a novel cytoskeleton-associated pp60src substrate.
Topics: Amino Acid Sequence; Animals; Avian Proteins; Base Sequence; Blotting, Northern; Blotting, Western; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cloning, Molecular; Cytoskeletal Proteins; Cytoskeleton; Microscopy, Fluorescence; Molecular Sequence Data; Oncogene Protein pp60(v-src); Phosphorylation; Protein Conformation; Repetitive Sequences, Nucleic Acid; Serine; Threonine; Tyrosine | 1991 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75.
Topics: Humans; Interleukin-2; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Interleukin-2; Threonine; Tyrosine | 1990 |
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1990 |
Metabolic depletion effect on serine/threonine- and tyrosine-phosphorylations of membrane proteins in human erythrocytes.
Topics: Autoradiography; Biological Transport; Casein Kinases; Cell Membrane Permeability; Cytosol; Erythrocyte Membrane; Erythrocytes; Humans; Membrane Proteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1990 |
Influence of secondary structure on the hydration of serine, threonine and tyrosine residues in proteins.
Topics: Amino Acids; Protein Conformation; Proteins; Serine; Stereoisomerism; Threonine; Tyrosine; Water; X-Ray Diffraction | 1990 |
Effects of protein phosphorylation with p43v-abl and protein kinase A catalytic subunit on fluorescence intensity.
Topics: Histones; Phosphopyruvate Hydratase; Phosphorylation; Protein Conformation; Protein Kinases; Serine; Spectrometry, Fluorescence; Threonine; Tyrosine | 1990 |
A simple and rapid method of quantitative analysis of phosphoamino acids by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1985 |
Resolution and identification of O-phosphoserine, O-phosphothreonine, O-phosphotyrosine, and gamma-carboxyglutamic acid as their fluorescent o-phthalaldehyde derivatives by high performance liquid chromatography.
Topics: 1-Carboxyglutamic Acid; Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; o-Phthalaldehyde; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1986 |
Determination of [32P]phosphoamino acids in protein hydrolysates by isocratic anion-exchange high-performance liquid chromatography.
Topics: Buffers; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Serine; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1988 |
Thin-layer chromatography can resolve phosphotyrosine, phosphoserine, and phosphothreonine in a protein hydrolyzate.
Topics: Animals; Autoradiography; Chromatography, Thin Layer; Humans; Hydrolysis; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1989 |
Antibodies and radioimmunoassays for phosphoserine, phosphothreonine and phosphotyrosine. Serologic specificities and levels of the phosphoamino acids in cytoplasmic fractions of rat tissues.
Topics: Animals; Antibodies; Antibody Specificity; Chromatography, Ion Exchange; Cytoplasm; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rabbits; Radioimmunoassay; Rats; Rats, Inbred F344; Serine; Serum Albumin, Bovine; Threonine; Tyrosine | 1989 |
Differences in protein digestibility and quality of liquid concentrate and powder forms of milk-based infant formulas fed to rats.
Topics: Amino Acids, Essential; Animals; Caseins; Cystine; Dietary Proteins; Digestion; Infant Food; Lactose; Lysine; Methionine; Nutritive Value; Powders; Rats; Threonine; Tyrosine | 1989 |
Threonine phosphorylation is associated with mitosis in HeLa cells.
Topics: Antibodies; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Interphase; Mitosis; Phosphorylation; Serine; Threonine; Tyrosine | 1989 |
Regulation of the insulin receptor kinase by hyperinsulinism.
Topics: Animals; Blotting, Western; Cell Line; Humans; Hyperinsulinism; Mice; Molecular Weight; Phosphorylation; Protein Kinases; Receptor, Insulin; Serine; Substrate Specificity; Threonine; Transfection; Tyrosine | 1989 |
Some observations on conserved polar side chains in immunoglobulin V-domains.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Immunoglobulin Variable Region; Protein Conformation; Threonine; Tyrosine | 1989 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Phosphorylation of protein tyrosine by human erythrocyte casein kinase A.
Topics: Angiotensin II; Ankyrins; Casein Kinases; Erythrocytes; Humans; Isoenzymes; Membrane Proteins; Peptides; Phosphorylation; Protein Kinases; Serine; Threonine; Tyrosine | 1986 |
Protein kinase C promotes the phosphorylation of immunoprecipitated middle T antigen from polyoma-transformed cells.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Calcimycin; Cell Transformation, Viral; Densitometry; Mice; Molecular Weight; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphorylation; Polyomavirus; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates; Vanadium | 1986 |
Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation.
Topics: Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1986 |
Regulation of the protein kinase activity of the human insulin receptor.
Topics: Enzyme Activation; Insulin; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Serine; Threonine; Tyrosine | 1987 |
Sequential metabolic characteristics following portacaval shunt in rats.
Topics: Amino Acids; Animals; Body Weight; Glucagon; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1986 |
A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates.
Topics: Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleoproteins; Organophosphonates; Peptide Fragments; Serine; Structure-Activity Relationship; Threonine; Tyrosine | 1987 |
Water solubilization of membrane proteins. Extensive derivatization with a novel polar derivatizing reagent.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Indicators and Reagents; Kinetics; Membrane Proteins; Models, Chemical; Serine; Solubility; Solvents; Threonine; Tyrosine; Water | 1988 |
Discrimination of Na+-independent transport systems L, T, and asc in erythrocytes. Na+ independence of the latter a consequence of cell maturation?
Topics: Amino Acids; Biological Transport, Active; Erythrocyte Aging; Erythrocytes; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Leucine; Sodium; Threonine; Tryptophan; Tyrosine | 1985 |
Effect of dietary level of protein or methionine and threonine on the amino acids and catecholamines in brain of rats fed a high tyrosine diet.
Topics: Amino Acids; Animals; Brain Chemistry; Catecholamines; Dietary Proteins; Male; Methionine; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Threonine; Tyrosine | 1985 |
Chemical modification of carboxypeptidase A crystals. Azo coupling with tyrosine-248.
Topics: Amino Acids; Aniline Compounds; Animals; Antibodies; Arsenicals; Azo Compounds; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Circular Dichroism; Cyanogen Bromide; Diazonium Compounds; gamma-Globulins; Magnetics; Peptides; Rabbits; Succinates; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1972 |
Studies on the enzymes involved in the biosynthesis of cyclo-tris (N-2,3-dihydroxybenzoyl-L-seryl) in Escherichia coli: kinetic properties of the L-serine-activating enzyme.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Anti-Bacterial Agents; Drug Stability; Enzyme Induction; Escherichia coli; Ethylmaleimide; Glycine; Gramicidin; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Phosphates; Phosphorus Radioisotopes; Proline; Serine; Threonine; Time Factors; Tritium; Tyrosine | 1973 |
[Relation between gamma-aminobutyric acid and tyrosine metabolism and changes in the brain and liver amino acid content in intact and adrenalectomized rats].
Topics: Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Liver; Lysine; Male; Rats; Serine; Stimulation, Chemical; Threonine; Tyrosine | 1972 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
Argininosuccinic aciduria in hereditary hair diseases.
Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Chromatography, Paper; Cystinuria; Female; Glutamates; Glutamine; Glycine; Hair; Histidine; Humans; Infant; Lysine; Male; Middle Aged; Serine; Skin Diseases; Threonine; Tyrosine; Valine | 1968 |
[Influence of changes in urinary pH on the excretion of amino acids from the isolated perfused rat kidney].
Topics: Alanine; Amino Acids; Animals; Arginine; Diffusion; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Leucine; Lysine; Perfusion; Rats; Serine; Threonine; Tyrosine; Urine; Valine | 1967 |
O-sulfate esters of hydroxy amino acids in hydrolyzates of proteoglycans.
Topics: Amino Acids; Animals; Cartilage; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Esters; Glycosaminoglycans; Hydrochloric Acid; Hydrolysis; Hydroxyproline; Methods; Potassium; Serine; Sulfates; Sulfuric Acids; Threonine; Tyrosine | 1972 |
Primary structure of insoluble tendon collagen. II. N- and C-terminal positional analysis of collagenolytic breakdown products of trypsin-pretreated collagen.
Topics: Achilles Tendon; Alanine; Amino Acids; Animals; Arginine; Cattle; Collagen; Glycine; Hydroxyproline; Isoleucine; Leucine; Methionine; Methods; Microbial Collagenase; Phenylalanine; Proline; Threonine; Trypsin; Tyrosine | 1968 |
The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Glutamates; Glycine; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lysine; Methionine; Periodic Acid; Phenylalanine; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan; Tyrosine | 1968 |
[Action of the amino acids plus sulfite combination on the growth of Clostridium. Trypticase-glucose-tyrosine-sulfite (TGTS) medium].
Topics: Amino Acids; Clostridium; Clostridium botulinum; Clostridium perfringens; Culture Media; Glucose; Sulfites; Temperature; Threonine; Tyrosine | 1970 |
Isolation of amino acid acceptor RNA from purified avian myeloblastosis virus.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Avian Leukosis Virus; Centrifugation, Density Gradient; Chick Embryo; Glycine; In Vitro Techniques; Isoleucine; Ligases; Methionine; Phenylalanine; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Mutant strains of Escherichia coli K12 that use D-amino acids.
Topics: Amino Acids; Arginine; Chromosome Mapping; Coliphages; D-Amino-Acid Oxidase; Escherichia coli; Genetic Linkage; Genotype; Histidine; Isoleucine; Isomerism; Leucine; Lysine; Mutation; Phenylalanine; Proline; Serine; Threonine; Transduction, Genetic; Tryptophan; Tyrosine; Valine | 1971 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Composition of the rhodopsin-core obtained by proteolysis of retinal rod outer segments with papain, and its regenerability after photobleaching.
Topics: Alanine; Animals; Arginine; Carbohydrates; Cattle; Chromatography, Thin Layer; Electrophoresis; Glutamates; Glycine; Histidine; Leucine; Light; Lysine; Papain; Photoreceptor Cells; Retinal Pigments; Retinaldehyde; Rhodopsin; Threonine; Tryptophan; Tyrosine | 1974 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
L-dihydroxyphenylalanine: effect on levels of free amino acids in rat liver.
Topics: Amino Acids; Animals; Aspartic Acid; Dihydroxyphenylalanine; Glutamates; Isoleucine; Liver; Male; Methionine; Organ Size; Rats; Serine; Threonine; Tyrosine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Duodenal protein infusions and plasma glucose, urea and amino acid levels in sheep.
Topics: Amino Acids; Animals; Blood Glucose; Caseins; Dietary Proteins; Duodenum; Eggs; Glycine max; Male; Sheep; Threonine; Tyrosine; Urea; Valine | 1974 |
Separation and translation of the mRNAs coding for and chains of rabbit globin.
Topics: Animals; Carbon Isotopes; Carcinoma, Krebs 2; Cell Fractionation; Cell-Free System; Centrifugation, Density Gradient; Electrophoresis, Paper; Genetic Code; Globins; Methionine; Peptide Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Sulfur Isotopes; Threonine; Tritium; Trypsin; Tyrosine | 1972 |
Specific glycine--accumulating synaptosomes in the spinal cord of rats.
Topics: Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain Stem; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Cerebral Cortex; Glutamates; Glycine; Leucine; Lysine; Male; Nerve Endings; Proline; Rats; Spinal Cord; Subcellular Fractions; Synaptic Vesicles; Synaptosomes; Threonine; Tritium; Tyrosine | 1972 |
High-resolution proton NMR studies of low affinity hemoglobins.
Topics: Asparagine; Aspartic Acid; Binding Sites; Carbon Isotopes; Deuterium; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Iron; Japan; Kansas; Magnetic Resonance Spectroscopy; Methylation; Mutation; Oxyhemoglobins; Protein Binding; Protein Conformation; Threonine; Tyrosine | 1973 |
Plasma aminogram in pigs with infectious Escherichia coli diarrhea.
Topics: Acute Disease; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Escherichia coli Infections; Gastroenteritis; Leucine; Lysine; Methionine; Nutrition Disorders; Swine; Threonine; Tyrosine | 1972 |
Changes in levels of amino acid acceptors in tRNA from Escherichia coli grown under various conditions.
Topics: Amino Acyl-tRNA Synthetases; Aminobutyrates; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Densitometry; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorine; Mutation; Organophosphonates; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Temperature; Threonine; Time Factors; Transfer RNA Aminoacylation; Tyrosine; Valine | 1974 |
In vitro transcription of three adjacent E. coli transfer RNA genes.
Topics: Centrifugation, Density Gradient; Coliphages; DNA Viruses; DNA-Directed RNA Polymerases; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Glycine; Molecular Weight; Nucleic Acid Hybridization; Phosphorus Radioisotopes; RNA, Bacterial; RNA, Transfer; Threonine; Transcription, Genetic; Transduction, Genetic; Tyrosine | 1974 |
The tryptic peptides and terminal sequences of the protein from the cowpea strain of tobacco mosaic virus.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Hydrolysis; Peptides; Plant Diseases; Plants, Edible; Protein Denaturation; Threonine; Tobacco Mosaic Virus; Trypsin; Tyrosine; Viral Proteins | 1972 |
Assimilation and toxicity of exogenous amino acids in the methane-oxidizing bacterium Methylococcus capsulatus.
Topics: Amino Acids; Aspartic Acid; Bacteria; Carbon Isotopes; Histidine; Homoserine; Lysine; Methionine; Phenylalanine; Threonine; Tyrosine | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
[Methionine toxicity. 5. Amino acid content of blood serum and urine after high doses of methionine and gaseous elimination of 35S from 35S methionine].
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Glutathione; Glycine; Histidine; Lysine; Methionine; Phenylalanine; Rats; Sulfur Isotopes; Taurine; Threonine; Time Factors; Tyrosine | 1972 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
Surface binding of amino acids by L1210 cells at 4 degrees C.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Biological Transport, Active; Cell Line; Cell Membrane; Histidine; Hydrogen-Ion Concentration; Hydroxylation; Isoleucine; Leucine; Leukemia L1210; Lipids; Mice; Phenylalanine; Solubility; Structure-Activity Relationship; Threonine; Tyrosine; Water | 1973 |
Stereospecificity of blood-brain barrier permeability to amino acids.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Rats; Threonine; Tritium; Tryptophan; Tyrosine; Valine | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Relationship of protein metabolism to senescence of corn (Zea mays L.) stalk parenchyma, cob parenchyma and first developed leaf tissues.
Topics: Aging; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cell Count; Chromatography; Dactinomycin; Glutamine; Leucine; Models, Biological; Ornithine; Phenylalanine; Plant Proteins; Plants; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Threonine; Time Factors; Tyrosine | 1973 |
Saturation of blood brain barrier transport of amino acids in phenylketonuria.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Humans; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
The effects of diets containing raw soya-bean flour on the vitamin B 12 status of rats.
Topics: Animals; Body Weight; Dietary Proteins; Food, Fortified; Glycine max; Humans; Liver; Male; Malonates; Methionine; Rats; Sex Factors; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Amino acid requirement of the growing rabbits: an estimate of quantitative needs.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Cystine; Female; Glycine; Glycine max; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Plant Proteins; Rabbits; Species Specificity; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
Alterations in renal and plasma amino acid concentrations during renal compensatory growth.
Topics: Alanine; Amino Acids; Animals; Kidney; Kidney Cortex; Leucine; Male; Methionine; Nephrectomy; Ornithine; Rats; Serine; Starvation; Threonine; Tyrosine | 1973 |
Hatching, attachment, and outgrowth of mouse blastocysts in vitro: fixed nitrogen requirements.
Topics: Amino Acids, Essential; Animals; Blastocyst; Chorionic Gonadotropin; Collagen; Culture Media; Cystine; Female; Glutamine; Gonadotropins, Equine; Histidine; Immune Sera; In Vitro Techniques; Methionine; Mice; Nitrogen; Ovulation; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
[A possibility to improve the protein quality of Baladi bread by enrichment with synthetic amino acids].
Topics: Amino Acids; Animal Feed; Animals; Body Weight; Bread; Dietary Proteins; Egypt; Flour; Food Additives; Food Analysis; Lysine; Male; Methionine; Rats; Threonine; Tyrosine | 1973 |
Studies on tyrosine environments of chicken ovomucoid. The environment of the most-exposed tyrosine.
Topics: Absorption; Alanine; Amino Acid Sequence; Amino Acids; Animals; Chickens; Chromatography, Ion Exchange; Chromatography, Thin Layer; Egg Proteins; Glutamine; Glycine; Lysine; Methane; Mucoproteins; Neuraminic Acids; Nitro Compounds; Peptide Fragments; Spectrum Analysis; Threonine; Tyrosine | 1973 |
Synthesis and catalytic properties of the heptapeptide L-seryl-L-prolyl-L-cysteinyl-L-steryl-alpha-L-glutamyl-L-threonyl-L-tyrosine.
Topics: Acetates; Carboxypeptidases; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dicyclohexylcarbodiimide; Esters; Glutamates; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrophenols; Oligopeptides; Optical Rotation; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Threonine; Tyrosine | 1974 |
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidine; Humans; Isoleucine; Leucine; Malabsorption Syndromes; Male; Malonates; Methionine; Proteinuria; Renal Tubular Transport, Inborn Errors; Reticulocytes; Serine; Taurine; Threonine; Tyrosine; Valine; Vitamin B 12; Vitamin B 12 Deficiency | 1974 |
Growth of human diploid fibroblasts in media with different amino acid composition.
Topics: Amino Acids; Cell Adhesion; Cell Division; Culture Media; Cystine; Fibroblasts; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Methionine; Phenylalanine; Pyruvates; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1974 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Aminoacyl transfer ribonucleic acid synthetases from cell-free extract of Plasmodium berghei.
Topics: Acridines; Amino Acids; Carbon Isotopes; Cell-Free System; Escherichia coli; Genetic Code; Histidine; Leucine; Ligases; Liver; Lysine; Plasmodium; Proline; Pyrimethamine; Quinacrine; RNA, Transfer; Species Specificity; Stilbamidines; Threonine; Tyrosine; Valine | 1969 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
On the C-terminal amino acid of bacterial alpha-amylase.
Topics: Alanine; Amino Acid Sequence; Amylases; Aspartic Acid; Bacillus subtilis; Carbon; Chemical Phenomena; Chemistry; Electrophoresis; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Paper; Serine; Threonine; Tyrosine; Valine | 1968 |
Microbiological plate assay methods for free amino acid levels in blood.
Topics: Amino Acids; Arginine; Biological Assay; Culture Media; Cystine; Enterococcus faecalis; Histidine; Humans; Lactobacillus; Lysine; Methionine; Methods; Pediococcus; Threonine; Tryptophan; Tyrosine | 1969 |
Structure and properties of hemocyanins. IV. Dissociation of Helix pomatia hemocyanin by succinylation into functional subunits.
Topics: Anhydrides; Animals; Carbohydrates; Chemical Phenomena; Chemistry; Chromatography, Gel; Copper; Dextrans; Edetic Acid; Hemocyanins; Microscopy, Electron; Molecular Weight; Osmolar Concentration; Oxygen; Protein Binding; Serine; Snails; Spectrum Analysis; Succinates; Threonine; Tyrosine; Ultracentrifugation; Viscosity | 1969 |
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
Studies of maleylated chains of human IgM.
Topics: Alkylating Agents; Amino Acid Sequence; Amino Acids; Chromatography, Gel; Electrophoresis, Disc; Guanidines; Humans; Immunochemistry; Immunoglobulin M; Maleates; Molecular Weight; Oxidation-Reduction; Threonine; Tyrosine; Ultracentrifugation; Waldenstrom Macroglobulinemia | 1970 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
[Glycopeptides of immunoglobulins, Microheterogeneity of the oligosaccharide chains of an immunoglobulin M from Waldenstrom's disease].
Topics: Amino Acid Sequence; Aspartic Acid; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Fucose; Galactose; Glucosamine; Glutamates; Histidine; Humans; Immunoglobulin M; Immunoglobulins; Lysine; Mannose; Neuraminic Acids; Oligosaccharides; Papain; Peptides; Proline; Serine; Threonine; Tyrosine; Valine; Waldenstrom Macroglobulinemia | 1970 |
Carboxy-terminal structure of the chain of human IgA myeloma proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antigens; Aspartic Acid; Bence Jones Protein; Blood Protein Electrophoresis; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; Glutamates; Glycine; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin G; Iodine Isotopes; Methods; Models, Structural; Oxidation-Reduction; Peptides; Rabbits; Sulfides; Thiocyanates; Threonine; Tyrosine; Valine | 1971 |
Purification and partial characterization of four proteins from human parotid saliva.
Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Amylases; Blood Proteins; Chromatography, Gel; Cross Reactions; Electrophoresis, Disc; Esterases; Galactosidases; Glucuronidase; Glutamates; Glycine; Humans; Hydrogen-Ion Concentration; Immune Sera; Immunodiffusion; Iron; Isoelectric Focusing; Muramidase; Parotid Gland; Peptide Hydrolases; Peroxidases; Proline; Proteins; Ribonucleases; Saliva; Threonine; Tyrosine; Ultracentrifugation | 1971 |
Characteristics of amino acid accumulation by synaptosomal particles isolated from rat brain.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Carbon Isotopes; Leucine; Lysine; Nerve Endings; Ouabain; Potassium; Proline; Rats; Serine; Sodium; Stimulation, Chemical; Synaptic Vesicles; Synaptosomes; Threonine; Tyrosine; Valine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
Plasma amino acid response in young men given diets devoid of single essential amino acids.
Topics: Adolescent; Adult; Amino Acids; Deficiency Diseases; Dietary Proteins; Fasting; Female; Humans; Isoleucine; Leucine; Lysine; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1972 |
Specific O-acylation of hydroxylamino acids in presence of free amino groups.
Topics: Acetates; Acylation; Amino Acids; Animals; Carboxylic Acids; Cattle; Chemical Phenomena; Chemistry; Chlorine; Drug Stability; Fluoroacetates; Insulin; Pancreas; Peptides; Ribonucleases; Serine; Spectrophotometry; Threonine; Tyrosine; Ultraviolet Rays | 1972 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary Proteins; Glycine; Isoleucine; Leucine; Lysine; Male; Methionine; Proline; Proteins; Serine; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1971 |
Amino acid supplementation of opaque-2 corn diets for growing rats.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cystine; Dietary Proteins; Growth; Isoleucine; Lysine; Male; Methionine; Nitrogen; Nutritional Requirements; Phenylalanine; Rats; Stimulation, Chemical; Threonine; Tyrosine; Valine; Zea mays | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Arginine, ornithine and proline metabolism of chicks: influence of diet and heredity.
Topics: Amino Acid Oxidoreductases; Amino Acids; Aminoisobutyric Acids; Animals; Arginase; Arginine; Chickens; Depression, Chemical; Diet; Glutamates; Histidine; Kidney; Liver; Lysine; Organ Specificity; Ornithine; Oxidoreductases; Proline; Pyrroles; Selection, Genetic; Species Specificity; Stimulation, Chemical; Threonine; Transaminases; Tyrosine | 1971 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Comparison of amino acid concentrations between plasma and erythrocytes. Studies in normal human subjects and those with metabolic disorders.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Aspartic Acid; Biological Transport; Child; Chromatography, Ion Exchange; Cystine; Erythrocytes; Glutamates; Glutathione; Glycine; Histidine; Homocystine; Homocystinuria; Humans; Infant; Maple Syrup Urine Disease; Methionine; Ornithine; Phenylketonurias; Plasma; Renal Tubular Transport, Inborn Errors; Serine; Spectrophotometry; Threonine; Tyrosine | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
[Thin-layer chromatography of rat serum in A vitamin hypervitaminosis].
Topics: Amino Acids; Animals; Blood Proteins; Chromatography, Thin Layer; Hydrolysis; Liver; Rats; Threonine; Tissue Extracts; Tyrosine; Vitamin A; Vitamin A Deficiency | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Transfer RNA species in normal and leukemic human lymphoblasts.
Topics: Amino Acids; Carbon Isotopes; Cell Line; Chromatography; Glutamine; Glycine; Humans; Leucine; Leukemia, Lymphoid; Ligases; Lymphocytes; Proline; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine | 1970 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
The behaviour of aspartate semialdehyde as a precursor of the intra- and extracellular amino acids in Escherichia coli 26-26.
Topics: Aldehydes; Amino Acids; Aspartic Acid; Autoradiography; Carbon Isotopes; Cell Wall; Chromatography, Ion Exchange; Chromatography, Paper; Escherichia coli; Glycine; Lysine; Molecular Biology; Pimelic Acids; Spectrophotometry; Threonine; Tyrosine; Valine | 1966 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
Effect of cholesteryl 14-methylhexadecanoate on the activity of some amino acid-transfer ribonucleic acid ligases from mammalian tissues.
Topics: Alanine; Animals; Carbon Isotopes; Ligases; Liver; Pancreas; Rats; RNA, Transfer; Sterols; Threonine; Tritium; Tryptophan; Tyrosine | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
[On the influence of contraceptive pills on serum amino acids in comparison with results typical for sex, menstrual cycle and pregnancy].
Topics: Adult; Alanine; Amino Acids; Citric Acid Cycle; Contraceptives, Oral; Female; Glycine; Humans; Isoleucine; Leucine; Male; Menstruation; Methionine; Pregnancy; Proline; Sex Factors; Threonine; Tyrosine; Urea; Valine | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
[Enrichment with vitamins B and catalytic activity of enzymes].
Topics: Catalysis; Culture Media; Dietary Carbohydrates; Enzyme Induction; Food Additives; Liver; Pyridoxine; Thiamine; Threonine; Tyrosine; Vitamin B Complex | 1969 |
Purity of amino acids.
Topics: Amino Acids; Arginine; Biological Assay; Cysteine; Histidine; Lysine; Methionine; Pediococcus; Streptococcus; Threonine; Tryptophan; Tyrosine | 1970 |
Amino acid interactions in chick nutrition. 1. The interrelationship between lysine and arginine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Body Weight; Chickens; Cobalt; Copper; Electrolytes; Female; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Manganese; Molybdenum; Nutritional Requirements; Phenylalanine; Selenium; Threonine; Tyrosine; Vitamins; Zinc | 1970 |
The amino acid composition of gray matter ganglioside-peptides of normal human and Tay-Sachs brains.
Topics: Alanine; Amino Acids; Aspartic Acid; Brain Chemistry; Chromatography, Ion Exchange; Cystine; Gangliosides; Glycine; Humans; Isoleucine; Leucine; Lipidoses; Methionine; Peptides; Threonine; Trypsin; Tyrosine; Valine | 1970 |
Molecular weight and amino acid composition of five-times-crystallized phosphoglucose isomerase from rabbit skeletal muscle.
Topics: Amides; Amino Acids; Animals; Barium; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Crystallization; Cysteine; Diffusion; Glucose-6-Phosphate Isomerase; Hydrochloric Acid; Hydroxides; Molecular Weight; Muscles; Nitrogen; Oxygen; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Ultracentrifugation; Viscosity | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Amino acid interactions in chick nutrition. 3. Interdependence in amino acid requirements.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Glycine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Effect of epinephrine and its precursors on activity of proteolytic enzymes.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Enzyme Activation; Epinephrine; Liver; Muscles; Peptide Hydrolases; Phenylalanine; Threonine; Tryptophan; Tyrosine | 1970 |
Response of adult rats to low dietary levels of essential amino acids.
Topics: Amino Acids; Animals; Body Weight; Cystine; Deficiency Diseases; Diet; Dietary Proteins; Female; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1970 |
Influence of time of fast on concentrations of free amino acids in plasma and total amino acids in liver protein of young swine.
Topics: Age Factors; Amino Acids; Animal Feed; Animals; Arginine; Chromatography, Ion Exchange; Cystine; Dietary Proteins; Fasting; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Swine; Threonine; Time Factors; Tyrosine; Valine | 1970 |
Glutamine in the phenylketonuric central nervous system.
Topics: Adolescent; Adult; Amino Acids; Biological Transport, Active; Brain; Brain Chemistry; Child; Female; Glutamine; Histidine; Humans; Intellectual Disability; Intelligence Tests; Male; Middle Aged; Phenylketonurias; Serine; Threonine; Tyrosine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
Molecular conformation of L-dopa.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Dipeptides; Dopamine; Glycine; Hydrogen; Isomerism; Norepinephrine; Peptides; Phenylalanine; Rotation; Threonine; Tyrosine; X-Ray Diffraction | 1970 |
1-amino-2-phenylethane 1-phosphonic acid: a specific competitive inhibitor of phenylalanyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Kinetics; Leucine; Organophosphonates; Phenylalanine; Plants; Threonine; Tyrosine; Valine | 1970 |
Effect of essential amino acid restriction on the growth of female C57BL mice and their implanted BW10232 adenocarcinomas.
Topics: Adenocarcinoma; Amino Acids; Animals; Body Weight; Deficiency Diseases; Female; Isoleucine; Leucine; Lysine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Rats; Threonine; Transplantation, Homologous; Tryptophan; Tyrosine; Valine | 1971 |
Urinary amino acid excretion in patients with scleroderma.
Topics: Arginine; Aspartic Acid; Chelating Agents; Female; Glutamates; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Renal Aminoacidurias; Scleroderma, Systemic; Threonine; Tyrosine; Valine | 1971 |
Reaction of tobacco mosaic virus with maleic anhydride and some possible applications to x-ray diffraction analysis.
Topics: Amino Acids; Anhydrides; Autoradiography; Binding Sites; Carbon Isotopes; Centrifugation; Chemical Phenomena; Chemistry; Densitometry; Electrophoresis; Hydrogen-Ion Concentration; Hydrolysis; Hydroxylamines; Lysine; Maleates; Peptides; Serine; Spectrophotometry; Threonine; Tobacco Mosaic Virus; Trypsin; Tyrosine; Ultracentrifugation; Ultraviolet Rays; Viral Proteins; X-Ray Diffraction | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
[Identification of antibacterial antibiotics mutabillicin and sporangiomycin].
Topics: Actinomyces; Alanine; Amino Acids; Anti-Bacterial Agents; Ascomycota; Carbon; Chromatography, Thin Layer; Cystine; Electrophoresis; Hydrogen; Infrared Rays; Leucine; Nitrogen; Solubility; Spectrum Analysis; Sulfur; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1971 |
Response of oxidative phosphorylation in rat liver to prolonged protein depletion.
Topics: Animals; Arginine; Caseins; Cystine; Dietary Proteins; Glutamates; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Oxidative Phosphorylation; Oxygen Consumption; Phenylalanine; Phosphates; Protein Deficiency; Rats; Succinate Dehydrogenase; Succinates; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
[Paper chromatographic amino acids analysis of natural compounds].
Topics: Amino Acids; Arginine; Chemistry Techniques, Analytical; Chromatography, Paper; Cystine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Oxidation-Reduction; Phenylalanine; Proteins; Solvents; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Essential amino acids for milk protein synthesis in the in vitro secretory cell and stimulation by elevated levels.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Caseins; Cattle; Culture Techniques; Cystine; Female; Glutamine; Histidine; Isoleucine; Lactation; Lactoglobulins; Leucine; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Pregnancy; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Spinach ferredoxin. I. Amino acid composition and terminal sequences.
Topics: Amino Acid Sequence; Amino Acids; Chromatography; Chromatography, Gel; Ferredoxins; Hydroxyapatites; Leucine; Lysine; Molecular Weight; Nitrobenzenes; Threonine; Tyrosine; Valine; Vegetables | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Kinetics of the photochemical addition of [35S] cysteine to polynucleotides and nucleic acids.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; DNA; Kinetics; Methionine; Polynucleotides; RNA; Saccharomyces; Serine; Sulfur Isotopes; Threonine; Thymus Gland; Tyrosine; Ultraviolet Rays | 1968 |
The substrate specificity of guinea-pig plasma kallikrein.
Topics: Amides; Animals; Arginine; Chemical Phenomena; Chemistry; Esters; Guinea Pigs; Hydrogen-Ion Concentration; Kallikreins; Kinetics; Lysine; Serine; Threonine; Tyrosine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Autodigestion of the main proteolytically active component of the stem bromelain.
Topics: Alanine; Arginine; Bromelains; Chromatography; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
[Isolation and identification of a ninhydrin-positive complex from the brain under the effect of gamma-amino butyric acid].
Topics: Amino Acids; Aminobutyrates; Animals; Brain Chemistry; Carotid Arteries; Dogs; Drug Stability; Glycine; Indicators and Reagents; Injections, Intra-Arterial; Serine; Stimulation, Chemical; Threonine; Time Factors; Tyrosine | 1968 |
Effect of different patterns of excess amino acids on performance of chicks fed amino acid-deficient diets.
Topics: Amino Acids; Animals; Arginine; Body Weight; Chickens; Cystine; Deficiency Diseases; Diet Therapy; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Threonine; Tryptophan; Tyrosine | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
Urinary amino acid patterns in simple and complicated bilharziasis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Ascites; Chromatography, Paper; Cystinuria; Hepatomegaly; Humans; Liver Diseases; Male; Middle Aged; Schistosomiasis; Splenomegaly; Threonine; Tryptophan; Tyrosine | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
The influence of transplantable rat mammary carcinomas on the chemical composition of the host.
Topics: Alanine; Amino Acids; Animals; Arachidonic Acids; Carcinoma 256, Walker; Chromatography, Thin Layer; Fatty Acids; Fatty Acids, Nonesterified; Female; Glutamates; Leucine; Lipid Metabolism; Liver; Mammary Neoplasms, Experimental; Methylcholanthrene; Muscles; Neoplasm Transplantation; Oleic Acids; Palmitic Acids; Phospholipids; Rats; Threonine; Tyrosine | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
The effects of individual amino acids on the incorporation of labelled amino acids into proteins by brain homogenates.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Centrifugation; Female; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Rats; Spectrum Analysis; Threonine; Tyrosine; Valine | 1969 |
Studies on metabolism of vitamin A. 7. Lowered biosynthesis of ascorbic acid in vitamin A-deficient rats.
Topics: Animals; Ascorbic Acid; Blood; Chlorobutanol; Kidney; Liver; Microsomes; Oxidoreductases; Phenylalanine; Rats; Threonine; Tyrosine; Urine; Vitamin A Deficiency | 1964 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Studies on the metabolism of larval tapeworms (Cyclophyllidea: Taenia crassiceps). I. Amino acid composition before and after in vitro culture.
Topics: Amino Acids; Animals; Arginine; Body Fluids; Chromatography, Paper; In Vitro Techniques; Mice; Peritoneal Cavity; Taenia; Threonine; Tissue Extracts; Tryptophan; Tyrosine | 1966 |
Effect of threonine on the toxicity of excess tyrosine and cataract formation in the rat.
Topics: Animals; Cataract; Protein Deficiency; Rats; Threonine; Tyrosine | 1966 |
Effect of tyrosine and threonine on free amino acids in plasma, liver, muscle, and eye in the rat.
Topics: Amino Acids; Animals; Blood; Eye; Histocytochemistry; Liver; Muscles; Rats; Threonine; Tyrosine | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
[Composition of the amino acid pool of Neurospora in deficiency of growth substance].
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Biotin; Choline; Chromatography, Ion Exchange; Culture Media; Glutamates; Glycine; Growth Inhibitors; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Pyridoxine; Riboflavin; Serine; Threonine; Tyrosine; Valine | 1966 |
[On the structure of protamine. VII. On the effect of the age of the fishes on the composition of their protamine].
Topics: Age Factors; Alanine; Amino Acids; Animals; Arginine; Fishes; Glutamates; Proline; Protamines; Serine; Threonine; Tyrosine; Valine | 1966 |
[Isolation and characteristics of the new antibacterial antibiotic mutabilicin (21-31)].
Topics: Actinomyces; Alanine; Amino Acids; Anti-Bacterial Agents; Chromatography, Paper; Cystine; Glycine; Infrared Rays; Peptides; Spectrophotometry; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
Free amino acids in gamma-irradiated carrots.
Topics: Acetates; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glutamates; Leucine; Methionine; Plants, Edible; Proline; Radiation Effects; Serine; Threonine; Tyrosine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Correlation between serine and thermal stability of collagen.
Topics: Animals; Annelida; Ascaris; Cattle; Collagen; Fishes; Hot Temperature; Humans; Hydroxyproline; Proline; Rats; Serine; Snails; Threonine; Tyrosine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Plasma amino acid pattern of chicks in relation to length of feeding period.
Topics: Amino Acids; Animals; Appetite Regulation; Arginine; Birds; Cystine; Dietary Proteins; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Threonine; Tyrosine; Valine | 1967 |
Effect of fasting and of feeding a nonprotein diet on plasma amino acid levels in the chick.
Topics: Amino Acids; Animals; Arginine; Birds; Cystine; Diet; Dietary Proteins; Fasting; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Threonine; Tyrosine; Valine | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
A comparison of the effect of dietary fat and carbohydrate on free amino acids in the blood plasma of chicks.
Topics: Amino Acids; Animals; Birds; Blood Glucose; Body Weight; Diet; Dietary Carbohydrates; Dietary Fats; Fats; Insulin; Leucine; Lysine; Methionine; Threonine; Tryptophan; Tyrosine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Effect of threonine on tyrosine metabolism of rats fed a low protein diet.
Topics: Amino Acids; Animals; Carbon Isotopes; Dietary Proteins; Liver; Male; Rats; Threonine; Tyrosine | 1967 |
Chromatographic analysis of free amino acids of gastric juice in patients with cancer and other stomach diseases.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Cystine; Duodenal Ulcer; Female; Gastric Juice; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Polyps; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The effect of progesterone on the concentration of plasma amino acids in man.
Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine | 1967 |
Separation of phosphohydroxyamino acids by high-performance liquid chromatography.
Topics: Animals; Catalysis; Cattle; Chromatography, High Pressure Liquid; Cyclic AMP; Hydrolysis; Myelin Basic Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Serine; Threonine; Tyrosine | 1982 |
Two-dimensional separation of phosphoamino acids from nucleoside monophosphates.
Topics: Adenosine Monophosphate; Chromatography, Thin Layer; Cytidine Monophosphate; Electrophoresis; Escherichia coli; Guanosine Monophosphate; Nucleotides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Thymidine Monophosphate; Tyrosine; Uracil Nucleotides; Uridine Monophosphate | 1982 |
Dansylation and high-performance liquid chromatographic separation of phosphoserine, phosphothreonine and phosphotyrosine from 32P-labeled protein hydrolyzates.
Topics: Animals; Binding Sites; Chromatography, High Pressure Liquid; Dansyl Compounds; Hydrolysis; In Vitro Techniques; Isotope Labeling; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Proteins; Rats; Serine; Threonine; Tyrosine | 1982 |
A rapid microdetermination of phosphoserine, phosphothreonine, and phosphotyrosine in proteins by automatic cation exchange on a conventional amino acid analyzer.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Hydrolysis; Myocardium; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Rats; Serine; Threonine; Tyrosine | 1983 |
Polyamide thin-layer chromatography of phosphorylated tyrosine, threonine, and serine.
Topics: Chromatography, Thin Layer; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tyrosine | 1983 |
Phosphorylation of tyrosine in cultured human placenta.
Topics: Culture Techniques; Female; Gestational Age; Humans; Phosphoproteins; Phosphorylation; Phosphotyrosine; Placenta; Pregnancy; Protein Kinases; Protein-Tyrosine Kinases; Serine; Threonine; Tyrosine | 1984 |
Chemical properties, isolation, and analysis of O-phosphates in proteins.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Hydrolysis; Indicators and Reagents; Phosphoproteins; Phosphorus Radioisotopes; Phosphoserine; Phosphothreonine; Phosphotyrosine; Serine; Threonine; Tritium; Tyrosine | 1984 |
Phosphorylation of threonine in the proline-rich carboxy-terminal region of simian virus 40 large T antigen.
Topics: Amino Acid Sequence; Antigens, Neoplasm; Antigens, Viral; Antigens, Viral, Tumor; Peptide Fragments; Phosphorylation; Simian virus 40; Threonine; Tyrosine | 1981 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Plasma and cerebrospinal fluid amino acid concentrations in phenylketonuria during the newborn period.
Topics: Amino Acids; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Phenylketonurias; Threonine; Tyrosine | 1981 |
Alteration in plasma amino acid concentrations following subtotal hepatectomy in dogs.
Topics: Amino Acids; Animals; Dogs; Female; Hepatectomy; Hepatic Encephalopathy; Isoleucine; Leucine; Male; Methionine; Phenylalanine; Threonine; Tyrosine; Valine | 1981 |
Limk1 is predominantly expressed in neural tissues and phosphorylates serine, threonine and tyrosine residues in vitro.
Topics: Amino Acid Sequence; Animals; Base Sequence; Central Nervous System; Chromosome Mapping; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Humans; Lim Kinases; Mice; Molecular Sequence Data; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Messenger; Serine; Threonine; Tyrosine | 1995 |
Tyrosine dephosphorylation of pp60c-src is stimulated by a serine/threonine phosphatase inhibitor.
Topics: 3T3 Cells; Animals; Enzyme Activation; Ethers, Cyclic; Fibroblasts; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Serine; Threonine; Tyrosine | 1994 |
The synthesis and use of pp60src-related peptides and phosphopeptides as substrates for enzymatic phosphorylation studies.
Topics: Amino Acid Sequence; Casein Kinases; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Phosphopeptides; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins pp60(c-src); Substrate Specificity; Threonine; Tyrosine | 1993 |
Hexokinase autophosphorylation: identification of a new dual specificity protein kinase.
Topics: Animals; Hexokinase; Isoenzymes; Phosphorylation; Rats; Serine; Staining and Labeling; Substrate Specificity; Threonine; Tyrosine | 1994 |
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Enzyme Activation; HeLa Cells; Humans; Inflammation; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Weight; Osmolar Concentration; Phosphorylation; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Sequence Deletion; Stress, Physiological; Subcellular Fractions; Substrate Specificity; Threonine; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
Topics: Alkaloids; Animals; Enzyme Inhibitors; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein Tyrosine Phosphatases; Rats; Receptor, Insulin; Serine; Staurosporine; Threonine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.
Topics: Amino Acid Sequence; Antibody Specificity; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Fungal Proteins; G1 Phase; MAP Kinase Kinase Kinases; Mating Factor; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Peptides; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Threonine; Tyrosine | 1995 |
Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes.
Topics: Animals; Antibodies, Monoclonal; Cell Cycle; Cell Line; Chromosomes; Detergents; Epitopes; Fluorescent Antibody Technique; Immunoblotting; Kinetochores; Macropodidae; Mice; Microscopy, Immunoelectron; Mitosis; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Threonine; Tyrosine | 1995 |
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element.
Topics: Amino Acid Sequence; Binding Sites; Cells, Cultured; Cysteine; Disulfides; Extracellular Matrix; Glycine; Humans; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Receptors, Glycine; Serine; Strychnine; Taurine; Threonine; Tyrosine | 1995 |
The Wee1 protein kinase regulates T14 phosphorylation of fission yeast Cdc2.
Topics: Base Sequence; cdc25 Phosphatases; Cell Cycle Proteins; Checkpoint Kinase 1; G2 Phase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Threonine; Tyrosine | 1995 |
Improved excitation pulse bandwidths using shaped pulses, with application to heteronuclear half filters in macromolecular NMR.
Topics: Bacterial Proteins; Carbon Isotopes; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen; Image Enhancement; Macromolecular Substances; Magnetic Resonance Spectroscopy; Methionine; Nitrogen Isotopes; Repressor Proteins; Threonine; Tyrosine; Valine | 1995 |
Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; Cysteine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Genetic Linkage; Humans; Insulin; Japan; Kinetics; Macromolecular Substances; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Polymerase Chain Reaction; Receptor, Insulin; Recombinant Proteins; Threonine; Transfection; Tyrosine | 1995 |
Characterization of a human protein threonine kinase isolated by screening an expression library with antibodies to phosphotyrosine.
Topics: Amino Acid Sequence; Bacteria; Base Sequence; Histidine; Humans; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Substrate Specificity; Threonine; Tyrosine | 1993 |
Rapid phosphorylation and selective dephosphorylation of P-selectin accompanies platelet activation.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Collagen; Epinephrine; Humans; Kinetics; Molecular Sequence Data; Oligopeptides; P-Selectin; Phosphorylation; Platelet Activation; Platelet Membrane Glycoproteins; Serine; Threonine; Thrombin; Tyrosine | 1993 |
Requirement of serine phosphorylation for formation of STAT-promoter complexes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Nucleus; Ciliary Neurotrophic Factor; Cytoplasm; DNA; DNA-Binding Proteins; Humans; Interleukin-6; Isoquinolines; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Phosphorylation; Piperazines; Promoter Regions, Genetic; Serine; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Threonine; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1995 |
Platelet talin is phosphorylated by calyculin A.
Topics: Alkalies; Antibodies, Monoclonal; Blood Platelets; Electrophoresis, Polyacrylamide Gel; Humans; Isotope Labeling; Marine Toxins; Oxazoles; Peptides; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Precipitin Tests; Serine; Talin; Threonine; Tyrosine | 1995 |
Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase.
Topics: Amino Acid Sequence; Base Sequence; Centrosome; Genes, Fungal; Genes, Lethal; Genomic Library; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine; Substrate Specificity; Threonine; Tyrosine | 1995 |
Progesterone binding to uteroglobin: two alternative orientations of the ligand.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Gene Expression; Models, Molecular; Molecular Sequence Data; Mutagenesis, Insertional; Point Mutation; Progesterone; Protein Binding; Protein Conformation; Protein Engineering; Protein Structure, Tertiary; Recombinant Fusion Proteins; Serine Endopeptidases; Threonine; Tyrosine; Uteroglobin | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the internalization of the rat neurotensin receptor.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line; Cysteine; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Neurotensin; Threonine; Tyrosine | 1995 |
Tyrosine phosphorylation of measles virus nucleocapsid protein in persistently infected neuroblastoma cells.
Topics: 2',5'-Oligoadenylate Synthetase; Capsid; eIF-2 Kinase; Humans; Measles virus; Neuroblastoma; Nucleocapsid Proteins; Nucleoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Tumor Cells, Cultured; Tyrosine; Viral Proteins | 1995 |
Stage-specific regulation of protein phosphorylation in Leishmania major.
Topics: Animals; In Vitro Techniques; Leishmania major; Molecular Weight; Phosphorylation; Protein Kinases; Protozoan Proteins; Serine; Signal Transduction; Threonine; Tyrosine | 1994 |
Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.
Topics: 3T3 Cells; Adipocytes; Animals; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Glucose; Insulin; Insulin Receptor Substrate Proteins; Mice; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Receptor, Insulin; Serine; Signal Transduction; Threonine; Tyrosine | 1994 |
Glutamine force-feeding effect on plasma amino-acid concentrations in growing rats fed a cafeteria diet.
Topics: Aging; Amino Acids; Animals; Cysteine; Diet; Glutamine; Ornithine; Proline; Rats; Rats, Wistar; Threonine; Tyrosine | 1994 |
Insulin receptor mutation at tyrosines 1162 and 1163 alters both receptor serine phosphorylation and desensitization.
Topics: Animals; CHO Cells; Cricetinae; Desensitization, Immunologic; Glycogen; Humans; Insulin; Mutation; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1994 |
Involvement of threonine 234 in catalysis of tyrosyl adenylate formation by tyrosyl-tRNA synthetase.
Topics: Adenosine Monophosphate; Base Sequence; Cadmium; Catalysis; Escherichia coli; Gene Expression; Geobacillus stearothermophilus; Kinetics; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Structure-Activity Relationship; Thermodynamics; Threonine; Transformation, Bacterial; Tyrosine; Tyrosine-tRNA Ligase | 1993 |
Role of hydroxyl-bearing amino acids in differentially tuning the absorption spectra of the human red and green cone pigments.
Topics: Cell Line; Humans; Light; Models, Molecular; Mutagenesis, Site-Directed; Photoreceptor Cells; Polymorphism, Genetic; Recombinant Proteins; Retinal Pigments; Serine; Spectrophotometry; Threonine; Transfection; Tyrosine | 1993 |
Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Mice; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1993 |
Direct evidence for tyrosine and threonine phosphorylation and activation of mitogen-activated protein kinase by vasopressin in cultured rat vascular smooth muscle cells.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Culture Media, Serum-Free; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Kinetics; Mice; Muscle, Smooth, Vascular; Pertussis Toxin; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Threonine; Tyrosine; Virulence Factors, Bordetella | 1993 |
Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; cdc25 Phosphatases; Cloning, Molecular; Codon; Cyclins; Escherichia coli; Female; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oocytes; Phosphorylation; Proteins; Recombinant Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Threonine; Tyrosine; Xenopus | 1993 |
Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine.
Topics: Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Glycogen Synthase Kinase 3; Phosphorylation; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 1993 |
Importance of the conserved active-site residues Tyr7, Glu106 and Thr199 for the catalytic function of human carbonic anhydrase II.
Topics: Amino Acid Sequence; Binding Sites; Carbon Dioxide; Carbonic Anhydrases; Catalysis; Conserved Sequence; Dansyl Compounds; Glutamine; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Nitrophenols; Spectrometry, Fluorescence; Structure-Activity Relationship; Threonine; Tyrosine | 1993 |
Dephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphatase.
Topics: CDC2 Protein Kinase; cdc25 Phosphatases; Escherichia coli; HeLa Cells; Humans; Mitosis; Peptide Mapping; Phosphorylation; Proteins; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 1993 |
Mechanisms of p34cdc2 regulation.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Base Sequence; Binding, Competitive; CDC2 Protein Kinase; Cyclins; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Recombinant Proteins; Structure-Activity Relationship; Threonine; Tyrosine | 1993 |
Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15.
Topics: Amino Acid Sequence; Animals; CDC2-CDC28 Kinases; cdc25 Phosphatases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Enzyme Activation; Glutathione Transferase; HeLa Cells; Humans; Mice; Peptide Mapping; Phosphates; Phosphopeptides; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Recombinant Fusion Proteins; Threonine; Trypsin; Tyrosine | 1993 |
Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation.
Topics: Adenosine Triphosphate; Adipocytes; Adrenergic beta-Agonists; Animals; Cells, Cultured; Female; Hydrogen-Ion Concentration; Insulin; Insulin Antagonists; Isoproterenol; Peptide Mapping; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin; Serine; Threonine; Tyrosine | 1995 |
Isolation and characterisation of a uniquely regulated threonine, tyrosine phosphatase (TYP 1) which inactivates ERK2 and p54jnk.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Humans; Mice; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Threonine; Tyrosine | 1995 |
Amino acid side chains that define muscarinic receptor/G-protein coupling. Studies of the third intracellular loop.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Arginine; Carbachol; Cloning, Molecular; Conserved Sequence; GTP-Binding Proteins; Isoleucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Protein Structure, Secondary; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Structure-Activity Relationship; Threonine; Transfection; Tyrosine | 1996 |
Identification of insulin-stimulated phosphorylation sites on calmodulin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calmodulin; Casein Kinase II; CHO Cells; Cricetinae; Humans; In Vitro Techniques; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Insulin; Recombinant Proteins; Serine; Threonine; Tyrosine | 1996 |
Substrates containing phosphorylated residues adjacent to proline decrease the cleavage by proline-specific peptidases.
Topics: Amino Acid Sequence; Anilides; Aniline Compounds; Animals; Dipeptides; Endopeptidases; Flavobacterium; Humans; Hydrolysis; Kinetics; Molecular Conformation; Molecular Sequence Data; Oligopeptides; Phosphorylation; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Serine; Serine Endopeptidases; Substrate Specificity; Swine; Threonine; Tyrosine | 1996 |
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage.
Topics: Amino Acid Sequence; Animals; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA; DNA Damage; Dose-Response Relationship, Radiation; Half-Life; Humans; Mice; Molecular Sequence Data; Phosphorylation; Protein Binding; Rats; Threonine; Tyrosine; Ultraviolet Rays | 1996 |
Analysis of phosphorylation and mutation of tyrosine residues of calmodulin on its activation of the erythrocyte Ca(2+)-transporting ATPase.
Topics: Animals; Calcium-Transporting ATPases; Calmodulin; Enzyme Activation; Erythrocyte Membrane; Humans; Mutation; Phosphorylation; Serine; Swine; Threonine; Tyrosine | 1996 |
Reciprocal modulation of ATP-sensitive K+ channel activity in rat ventricular myocytes by phosphorylation of tyrosine and serine/threonine residues.
Topics: Adenosine Triphosphate; Animals; Myocardium; Phosphorylation; Potassium Channels; Rats; Rats, Sprague-Dawley; Serine; Threonine; Time Factors; Tyrosine | 1996 |
Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding, Competitive; Cell Division; Cell Line; Ciliary Neurotrophic Factor; Haptoglobins; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Rats; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Sequence Alignment; Solubility; Threonine; Tyrosine | 1996 |
The effect of condensed tannins from heated and unheated cottonseed on the ileal digestibility of amino acids for the growing rat and pig.
Topics: Amino Acids; Animals; Cottonseed Oil; Digestion; Female; Hot Temperature; Ileum; Lysine; Male; Rats; Rats, Sprague-Dawley; Swine; Tannins; Threonine; Tyrosine | 1996 |
Tyrosine phosphorylation of GSalpha and inhibition of bradykinin-induced activation of the cyclic AMP pathway in A431 cells by epidermal growth factor receptor.
Topics: Adenylyl Cyclases; Bradykinin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Humans; Isoproterenol; Oncogene Proteins; Phosphorylation; Serine; Threonine; Tumor Cells, Cultured; Tyrosine | 1996 |
Serine/threonine dephosphorylation may be involved in tyrosine phosphorylation: a new mode of signal transduction in platelets.
Topics: Blood Platelets; Humans; Okadaic Acid; Phosphorylation; Platelet Aggregation; Serine; Signal Transduction; Threonine; Tyrosine | 1996 |
Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Line; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; GRB2 Adaptor Protein; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Mutagenesis; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Rabbits; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Threonine; Tyrosine | 1996 |
The inhibitory effect of staurosporine on insulin action is prevented by okadaic acid. Evidence for an important role of serine/threonine phosphorylation in eliciting insulin-like effects.
Topics: Animals; Biological Transport; Enzyme Activation; Enzyme Inhibitors; Glucose; Insulin; Insulin Antagonists; Male; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Protein Phosphatase 1; Rats; Receptor, Insulin; Serine; Staurosporine; Threonine; Tyrosine | 1996 |
Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms.
Topics: Animals; Binding Sites; Casein Kinase II; Cell Line; Consensus Sequence; Dimerization; Gene Expression; Glycosylation; HeLa Cells; Herpesvirus 3, Human; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Fc; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Tyrosine; Viral Envelope Proteins | 1997 |
Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor.
Topics: Amino Acid Sequence; Animals; Endocytosis; Fluorescent Antibody Technique, Indirect; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Neurokinin-1; Serine; Threonine; Tyrosine | 1997 |
Very fast electron transfer from cytochrome to the bacterial photosynthetic reaction center at low temperature.
Topics: Cytochrome c Group; Electron Transport; Kinetics; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Rhodopseudomonas; Spectrum Analysis; Temperature; Threonine; Tyrosine | 1997 |
Differential surface expression and phosphorylation of the N-methyl-D-aspartate receptor subunits NR1 and NR2 in cultured hippocampal neurons.
Topics: Animals; Cell Membrane; Cells, Cultured; Female; Hippocampus; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Threonine; Tyrosine | 1997 |
Tyrosine phosphorylation of measles virus P-phosphoprotein in persistently infected neuroblastoma cells.
Topics: Animals; CSK Tyrosine-Protein Kinase; Measles virus; Mice; Neuroblastoma; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Serine; src-Family Kinases; Threonine; Tumor Cells, Cultured; Tyrosine; Viral Proteins; Virus Latency | 1996 |
Order of amino acid limitation in meat and bone meal.
Topics: Amino Acids; Animals; Biological Products; Chickens; Chromatography, Ion Exchange; Cystine; Diet; Female; Food, Fortified; Leucine; Male; Meat; Methionine; Minerals; Threonine; Tyrosine; Valine | 1997 |
The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues.
Topics: Adenosine Triphosphate; Animals; Baculoviridae; Cloning, Molecular; Escherichia coli; Humans; Luciferases; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Serine; Spodoptera; Threonine; Transfection; Tyrosine | 1997 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
Detection of ERK activation by a novel monoclonal antibody.
Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; COS Cells; Drosophila melanogaster; Enzyme Activation; Epidermal Growth Factor; Eukaryota; HeLa Cells; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Point Mutation; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Signal Transduction; Spodoptera; Threonine; Transfection; Tyrosine | 1997 |
Transcriptional regulation of Sertoli cell immediate early genes by interleukin-6 and interferon-gamma is mediated through phosphorylation of STAT-3 and STAT-1 proteins.
Topics: Animals; Antineoplastic Agents; DNA; DNA-Binding Proteins; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Genistein; Interferon-gamma; Interleukin-6; Isoflavones; Male; Models, Molecular; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA; Serine; Sertoli Cells; STAT1 Transcription Factor; STAT3 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Tyrosine | 1997 |
Generation of phosphorylated cyclin-dependent kinase 2 and functional characterization of threonine-160-specific phosphatase KAP.
Topics: Adenosine Triphosphate; Autoradiography; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Chromatography, Affinity; Cloning, Molecular; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor Proteins; Cyclin-Dependent Kinases; Cyclins; Dual-Specificity Phosphatases; Escherichia coli; Glutathione Transferase; Humans; Phosphorus Radioisotopes; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Sequence Tagged Sites; Substrate Specificity; Threonine; Tyrosine | 1997 |
Differential regulation of extracellular signal-regulated kinase 1 and 2 activity during 12-O-tetradecanoylphorbol 13-acetate-induced differentiation of HL-60 cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; HL-60 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Peptides; Phosphorylation; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1997 |
Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen.
Topics: 3T3 Cells; Animals; Antigens, Neoplasm; Antigens, Viral; Binding Sites; Mice; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Polyomavirus; Precipitin Tests; Protein Phosphatase 2; Substrate Specificity; Threonine; Tyrosine | 1997 |
Activation mechanism of the MAP kinase ERK2 by dual phosphorylation.
Topics: Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Crystallography; Dimerization; Enzyme Activation; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Phosphorylation; Proline; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Threonine; Tyrosine | 1997 |
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Caffeine; CDC2 Protein Kinase; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; Doxorubicin; Electrophoresis, Polyacrylamide Gel; G1 Phase; G2 Phase; Humans; Mice; Mitosis; Nocodazole; Paclitaxel; Phosphorylation; Protein Kinases; Threonine; Tumor Cells, Cultured; Tyrosine | 1997 |
Dual specificity of the interleukin 1- and tumor necrosis factor-activated beta casein kinase.
Topics: Amino Acid Sequence; Casein Kinases; Enzyme Activation; Humans; Interleukin-1; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphoserine; Protein Kinases; Signal Transduction; Structure-Activity Relationship; Substrate Specificity; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1997 |
The universal stress protein, UspA, of Escherichia coli is phosphorylated in response to stasis.
Topics: Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Heat-Shock Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Serine; Threonine; Transcription, Genetic; Tyrosine | 1997 |
Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation.
Topics: Calpain; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cysteine Endopeptidases; HeLa Cells; Humans; Leupeptins; Multienzyme Complexes; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Threonine; Tyrosine | 1997 |
The carboxy-terminal C2-like domain of the alpha-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition.
Topics: Amino Acid Sequence; Animals; Bacterial Toxins; Binding Sites; Calcium; Calcium-Binding Proteins; Cell Membrane; Clostridium perfringens; Culture Media; Humans; Molecular Sequence Data; Proline; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sheep; Threonine; Type C Phospholipases; Tyrosine | 1997 |
Stimulation of 42/44 kDa mitogen-activated protein kinases by arginine vasopressin in rat cardiomyocytes.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myelin Basic Protein; Myocardium; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Vasopressin; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vasoconstrictor Agents | 1998 |
Quick responses of plasma amino acid concentration to changes in dietary amino acid levels in rats.
Topics: Amino Acids, Essential; Animals; Arginine; Body Weight; Diet; Eating; Glycine; Isoleucine; Lysine; Male; Rats; Rats, Wistar; Threonine; Tyrosine; Valine | 1998 |
Identification of N-terminal residues on P-selectin glycoprotein ligand-1 required for binding to P-selectin.
Topics: Alanine; Amino Acid Sequence; Animals; CHO Cells; Cricetinae; DNA, Complementary; Humans; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis; P-Selectin; Protein Binding; Recombinant Proteins; Threonine; Tyrosine | 1998 |
Biochemical characterization of the 20S proteasome from the methanoarchaeon Methanosarcina thermophila.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine Endopeptidases; DNA, Archaeal; Escherichia coli; Glutamine; Ions; Lysine; Methanosarcina; Microscopy, Electron; Molecular Sequence Data; Multienzyme Complexes; Peptides; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Threonine; Tyrosine | 1998 |
The effect of a low-protein diet and dietary supplementation of threonine on tyrosine and 2-(2-nitro-4-trifluoromethylbenzoyl) cyclohexane-1,3-dione-induced corneal lesions, the extent of tyrosinemia, and the activity of enzymes involved in tyrosine catab
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Animals; Aqueous Humor; Corneal Diseases; Cyclohexanones; Dietary Proteins; Enzyme Inhibitors; Kidney; Liver; Male; Methionine; Nitrobenzoates; Rats; Rats, Wistar; Threonine; Tyrosine | 1998 |
Resistance gene N-mediated de novo synthesis and activation of a tobacco mitogen-activated protein kinase by tobacco mosaic virus infection.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Induction; Mitogen-Activated Protein Kinases; Molecular Weight; Nicotiana; Plant Proteins; Plants, Toxic; Protein Kinases; RNA, Messenger; Serine; Threonine; Tobacco Mosaic Virus; Tyrosine | 1998 |
Tyrosine and tryptophan act through the same binding site at the dimer interface of yeast chorismate mutase.
Topics: Allosteric Regulation; Binding Sites; Chorismate Mutase; Codon; Dimerization; Glycine; Models, Chemical; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Serine; Threonine; Tryptophan; Tyrosine | 1998 |
Information from the water stripe in TOCSY experiments on systems with exchangeable protons.
Topics: Amino Acids; Carbon; Cysteine; Electron Spin Resonance Spectroscopy; Hydrogen; Hydroxyl Radical; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Nitrogen; Peptides; Protons; Solvents; Sucrose; Threonine; Time Factors; Tyrosine; Water | 1998 |
Homozygous protein C deficiency with a double variant His 202 to Tyr and Ala 346 to Thr.
Topics: Alanine; Amino Acid Substitution; Base Sequence; Consanguinity; Genetic Variation; Histidine; Homozygote; Humans; Infant, Newborn; Male; Mutation; Pedigree; Protein C; Protein C Deficiency; Threonine; Tyrosine | 1998 |
Dual amino acid-selective and site-directed stable-isotope labeling of the human c-Ha-Ras protein by cell-free synthesis.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Carbon Isotopes; Carbon Radioisotopes; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Humans; Isotope Labeling; Models, Chemical; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oncogene Proteins v-raf; Proline; ras Proteins; Retroviridae Proteins, Oncogenic; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 1998 |
Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
Topics: Alanine; Amino Acid Sequence; DNA Repair; DNA-Binding Proteins; Enzyme Activation; Glutamic Acid; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Threonine; Tyrosine | 1998 |
Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport.
Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Enzyme Activation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Antagonists; Insulin Receptor Substrate Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Serine; Threonine; Tyrosine | 1998 |
The duration of phorbol-inducible ErbB2 tyrosine dephosphorylation parallels that of receptor endocytosis rather than threonine-686 phosphorylation: implications for the physiological role of protein kinase C in growth factor receptor signalling.
Topics: 3T3 Cells; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Animals; Endocytosis; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptor, ErbB-2; Receptors, Growth Factor; Threonine; Time Factors; Tyrosine | 1998 |
Direct effects of phosphorylation on the preferred backbone conformation of peptides: a nuclear magnetic resonance study.
Topics: Amino Acid Sequence; Biophysical Phenomena; Biophysics; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Oligopeptides; Phosphorylation; Protein Conformation; Serine; Threonine; Tyrosine | 1999 |
Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cytoplasm; Hydroxides; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Potassium; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thallium; Threonine; Tyrosine | 1998 |
CaMKII-dependent phosphorylation of NR2A and NR2B is decreased in animals characterized by hippocampal damage and impaired LTP.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Enzyme Activation; Female; Gene Expression; Hippocampus; In Situ Hybridization; Long-Term Potentiation; Methylazoxymethanol Acetate; Nerve Degeneration; Neurons; Organ Culture Techniques; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serine; Synapses; Threonine; Tyrosine | 1999 |
Modulation of the protein tyrosine kinase activity and autophosphorylation of the epidermal growth factor receptor by its juxtamembrane region.
Topics: Angiotensin II; Animals; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Humans; Ligands; Mice; Peptide Fragments; Phosphorylation; Polylysine; Protein-Tyrosine Kinases; Threonine; Tyrosine | 1999 |
Implication of TNF receptor-I-mediated extracellular signal-regulated kinases 1 and 2 (ERK1/2) activation in growth of AIDS-associated Kaposi's sarcoma cells: a possible role of a novel death domain protein MADD in TNF-alpha-induced ERK1/2 activation in K
Topics: Acquired Immunodeficiency Syndrome; Antibodies, Monoclonal; Antigens, CD; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Division; Dactinomycin; Death Domain Receptor Signaling Adaptor Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Growth Inhibitors; Growth Substances; Guanine Nucleotide Exchange Factors; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Sarcoma, Kaposi; Threonine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 1999 |
Functional role of oxygen-containing residues in the fifth transmembrane segment of the Na,K-ATPase alpha subunit.
Topics: Amino Acid Substitution; Asparagine; HeLa Cells; Humans; Mutagenesis, Site-Directed; Oxygen; Protein Conformation; Sodium-Potassium-Exchanging ATPase; Threonine; Tyrosine | 1999 |
Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Deoxyribonuclease I; DNA; Hydrolysis; Mutagenesis, Site-Directed; RNA, Transfer, Tyr; Serine; Substrate Specificity; Sugar Phosphates; Threonine; Thymidine; Tyrosine | 1999 |
Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3beta and Shaggy.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Drosophila; Drosophila Proteins; Eukaryotic Initiation Factor-2B; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Guanine Nucleotide Exchange Factors; Molecular Sequence Data; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
Amino acid biosynthesis in the halophilic archaeon Haloarcula hispanica.
Topics: Acetyl Coenzyme A; Amino Acid Oxidoreductases; Amino Acids; Bacteria; Carbon; Diaminopimelic Acid; Eukaryotic Cells; Evolution, Molecular; Glycerol; Haloarcula; Isoleucine; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Oxaloacetic Acid; Pyruvic Acid; Threonine; Tyrosine | 1999 |
Distinctions in the molecular determinants of charged and neutral dihydropyridine block of L-type calcium channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Dihydropyridines; Humans; Isradipine; Kinetics; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Structure, Secondary; Recombinant Fusion Proteins; Recombinant Proteins; Threonine; Transfection; Tyrosine; Verapamil | 1999 |
Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state.
Topics: 3T3 Cells; Animals; Biological Transport; CHO Cells; Cricetinae; Enzyme Activation; Glucose; Glucose Transporter Type 4; Glycogen; Insulin; Insulin Receptor Substrate Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Osmotic Pressure; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Signal Transduction; Threonine; Tyrosine | 1999 |
Inactivation of p34cdc2 kinase by the accumulation of its phosphorylated forms in porcine oocytes matured and aged in vitro.
Topics: Amino Acid Sequence; Animals; CDC2 Protein Kinase; Cells, Cultured; Cellular Senescence; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Fertilization in Vitro; Male; Maturation-Promoting Factor; Molecular Sequence Data; Oocytes; Phosphorylation; Swine; Threonine; Tyrosine | 1999 |
Molecular cloning and characterization of a novel member of the MAP kinase superfamily.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Calcium-Calmodulin-Dependent Protein Kinases; Chromosome Mapping; Chromosomes, Human, Pair 14; Cloning, Molecular; COS Cells; DNA, Complementary; Enzyme Activation; Expressed Sequence Tags; Female; Gene Expression; Glucose; Humans; Male; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Conformation; Receptor for Advanced Glycation End Products; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Threonine; Tissue Distribution; Tyrosine | 1999 |
Tyrosine phosphorylation of A17 during vaccinia virus infection: involvement of the H1 phosphatase and the F10 kinase.
Topics: Animals; Binding Sites; Cell Line; Chlorocebus aethiops; Dual Specificity Phosphatase 3; Escherichia coli; Membrane Proteins; Peptides; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Serine; Threonine; Tyrosine; Vaccinia virus; Viral Envelope Proteins; Viral Proteins | 1999 |
Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.
Topics: Amino Acid Sequence; Binding, Competitive; Cell Line; Humans; Membrane Proteins; Molecular Sequence Data; Muscarinic Agonists; Mutation; Proline; Protein Conformation; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Serine; Threonine; Tyrosine | 1999 |
Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2. A study with peptide substrates derived from immunophilin Fpr3.
Topics: Amino Acid Sequence; Casein Kinase II; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Peptidylprolyl Isomerase; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase.
Topics: Animals; Cell Line; COS Cells; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Kinetics; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Recombinant Proteins; Threonine; Transfection; Tyrosine | 1999 |
The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha.
Topics: Alleles; Cell Line; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Humans; Isoelectric Focusing; Phosphorylation; Protein Biosynthesis; Serine; Substrate Specificity; Threonine; Tyrosine | 1999 |
Distinct, constitutively active MAPK phosphatases function in Xenopus oocytes: implications for p42 MAPK regulation In vivo.
Topics: Animals; Enzyme Activation; Kinetics; MAP Kinase Kinase 1; Meiosis; Microinjections; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Threonine; Tyrosine; Vanadates; Xenopus | 1999 |
The C-terminal region of human glutathione transferase A1-1 affects the rate of glutathione binding and the ionization of the active-site Tyr9.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Enzyme Stability; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Threonine; Tyrosine | 1999 |
Binding of 14-3-3 protein to the plasma membrane H(+)-ATPase AHA2 involves the three C-terminal residues Tyr(946)-Thr-Val and requires phosphorylation of Thr(947).
Topics: 14-3-3 Proteins; Amino Acid Sequence; Arabidopsis; Cell Membrane; Molecular Sequence Data; Phosphorylation; Proteins; Proton-Translocating ATPases; Signal Transduction; Threonine; Tyrosine; Tyrosine 3-Monooxygenase; Valine | 1999 |
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Consensus Sequence; Eukaryotic Cells; Glycosylation; Models, Molecular; Neural Networks, Computer; Nuclear Proteins; Phosphoproteins; Phosphorylation; Phylogeny; Protein Structure, Tertiary; Reproducibility of Results; Sensitivity and Specificity; Serine; Substrate Specificity; Threonine; Trans-Activators; Tyrosine | 1999 |
Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation.
Topics: Acetylcysteine; Blotting, Western; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Threonine; Tyrosine; Vehicle Emissions | 2000 |
Modulation of human neutrophil responses to CD32 cross-linking by serine/threonine phosphatase inhibitors: cross-talk between serine/threonine and tyrosine phosphorylation.
Topics: Adult; Calcium; Calcium Signaling; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Marine Toxins; Neutrophil Activation; Neutrophils; Oncogene Protein v-cbl; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Receptors, IgG; Retroviridae Proteins, Oncogenic; Serine; Superoxides; Threonine; Tyrosine | 2000 |
Random-coil chemical shifts of phosphorylated amino acids.
Topics: Amino Acids; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorus Isotopes; Phosphorylation; Protein Structure, Secondary; Serine; Threonine; Tyrosine | 1999 |
Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites; Blotting, Western; Cell Nucleus; CHO Cells; Cricetinae; Cytoplasm; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Intracellular Fluid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphoric Monoester Hydrolases; Phosphorylation; Signal Transduction; Threonine; Transfection; Tyrosine | 2000 |
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
Topics: Amidohydrolases; Aminolevulinic Acid; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diazooxonorleucine; Electrons; Enzyme Inhibitors; Glutamic Acid; Glutamine; Pseudomonas; Threonine; Tyrosine | 2000 |
Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels.
Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; KCNQ Potassium Channels; KCNQ1 Potassium Channel; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Tetraethylammonium; Threonine; Transfection; Tyrosine | 2000 |
Induction of intracellular signalling by cyclic glycerophosphates and their deoxy analogues.
Topics: 3T3 Cells; Animals; CHO Cells; Cricetinae; Enzyme Activation; Glycerophosphates; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Threonine; Tyrosine | 2000 |
A screen for modifiers of cyclin E function in Drosophila melanogaster identifies Cdk2 mutations, revealing the insignificance of putative phosphorylation sites in Cdk2.
Topics: Animals; Binding Sites; Carrier Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; E2F Transcription Factors; Enhancer Elements, Genetic; Eye; Eye Proteins; Genes, Insect; Homeodomain Proteins; Insect Proteins; Larva; Membrane Glycoproteins; Mutagenesis; Nuclear Proteins; Phenotype; Phosphorylation; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Retinoblastoma-Binding Protein 1; RNA-Binding Proteins; Threonine; Trans-Activators; Transcription Factors; Tyrosine; Zygote | 2000 |
Towards models of vanadate-dependent haloperoxidases: the hydroxyl side chain.
Topics: Binding Sites; Cysteine; Homoserine; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Structure; Peroxidases; Protein Tyrosine Phosphatases; Serine; Threonine; Tyrosine; Vanadates | 2000 |
The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antigens, CD; Carrier Proteins; CD79 Antigens; Cytoplasm; Enzyme Inhibitors; Humans; Immunoglobulin Fragments; Immunoglobulin Variable Region; Molecular Sequence Data; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
The effects of sarin-like and soman-like organophosphorus agents on MAPK and JNK in rat brains.
Topics: Animals; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Coloring Agents; Cytosol; Diphosphonates; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Luminescent Measurements; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Sarin; Soman; Threonine; Tyrosine | 2000 |
Directed molecular evolution of cytochrome c peroxidase.
Topics: Alanine; Asparagine; Aspartic Acid; Cloning, Molecular; Cytochrome-c Peroxidase; Directed Molecular Evolution; Enzyme Activation; Gene Library; Genetic Vectors; Guaiacol; Point Mutation; Saccharomyces cerevisiae; Substrate Specificity; Threonine; Tyrosine | 2000 |
Melatonin-induced organelle movement in melanophores is coupled to tyrosine phosphorylation of a high molecular weight protein.
Topics: Adenylate Cyclase Toxin; Animals; Blotting, Western; Cell Aggregation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Genistein; GTP-Binding Proteins; Kinetics; Melanophores; Melatonin; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Virulence Factors, Bordetella; Xenopus | 2000 |
Correlating amino acid conservation with function in tyrosyl-tRNA synthetase.
Topics: Acylation; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Substitution; Arginine; Catalysis; Conserved Sequence; Enzyme Stability; Evolution, Molecular; Geobacillus stearothermophilus; Histidine; Kinetics; Lysine; Models, Genetic; Models, Molecular; Mutation; Protein Binding; Protein Conformation; RNA, Bacterial; RNA, Catalytic; RNA, Fungal; RNA, Transfer, Amino Acyl; Structure-Activity Relationship; Thermodynamics; Threonine; Tyrosine; Tyrosine-tRNA Ligase | 2000 |
DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; Cations; Chromatography, Agarose; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genistein; Guanosine Triphosphate; Humans; Magnesium; Manganese; Medulloblastoma; Mice; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Phosphates; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.
Topics: Animals; Cell Line; Cloning, Molecular; Enzyme Activation; Humans; Insecta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Osmosis; Peptide Mapping; Phosphorylation; Protein Isoforms; Serine; Substrate Specificity; Threonine; Trypsin; Tyrosine | 2000 |
Coupling of hydrogen bonding to chromophore conformation and function in photoactive yellow protein.
Topics: Ammonium Chloride; Ammonium Sulfate; Bacterial Proteins; Crystallography, X-Ray; Hydrogen Bonding; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenylalanine; Photolysis; Photoreceptors, Microbial; Pigments, Biological; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Threonine; Tyrosine; Valine | 2000 |
SIMKK, a mitogen-activated protein kinase (MAPK) kinase, is a specific activator of the salt stress-induced MAPK, SIMK.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA Primers; Enzyme Activation; Medicago sativa; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Plant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Threonine; Two-Hybrid System Techniques; Tyrosine | 2000 |
Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adipocytes; Animals; beta-Cyclodextrins; Carcinogens; Caveolae; Cell Differentiation; Cell Division; Cell Membrane; Cells, Cultured; Cholesterol; Cyclodextrins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucose; Immunoblotting; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mice; Microscopy, Electron; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Threonine; Time Factors; Tyrosine | 2001 |
Kinase suppressor of Ras signals through Thr269 of c-Raf-1.
Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Humans; Mice; Mutation; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Proteins; Serine; Signal Transduction; Threonine; Transfection; Tyrosine; Valine | 2001 |
The valine-to-threonine 75 substitution in human immunodeficiency virus type 1 reverse transcriptase and its relation with stavudine resistance.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Antiviral Agents; Binding Sites; Cell Line; DNA; DNA Repair; Drug Resistance; HeLa Cells; HIV Reverse Transcriptase; Humans; Inhibitory Concentration 50; Kinetics; Models, Molecular; Plasmids; Recombinant Proteins; Stavudine; Threonine; Time Factors; Transfection; Tyrosine; Valine; Zidovudine | 2001 |
Substrate and inhibitor specificities for human monoamine oxidase A and B are influenced by a single amino acid.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Baculoviridae; Catalysis; Clorgyline; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Glycine; Humans; Isoleucine; Kinetics; Molecular Sequence Data; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mutagenesis, Site-Directed; Mutation; Phenethylamines; Protein Isoforms; Psychotropic Drugs; Selegiline; Sequence Homology, Amino Acid; Serotonin; Substrate Specificity; Threonine; Tyrosine | 2001 |
Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
Topics: 3T3 Cells; Androstadienes; Animals; Cysteine Endopeptidases; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Okadaic Acid; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Serine; Sirolimus; Threonine; Time Factors; Tyrosine; Vanadates; Wortmannin | 2001 |
Tyrosine phosphorylation of p120(ctn) in v-Src transfected L cells depends on its association with E-cadherin and reduces adhesion activity.
Topics: Amino Acid Substitution; Animals; Base Sequence; Cadherins; Catenins; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Delta Catenin; DNA Primers; Mice; Oncogene Protein pp60(v-src); Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Serine; Threonine; Tyrosine | 2001 |
The juxtamembrane region of the epidermal growth factor receptor is required for phosphorylation of Galpha(s).
Topics: Amino Acids; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Escherichia coli; Heterotrimeric GTP-Binding Proteins; Humans; Intracellular Membranes; Models, Biological; Peptide Mapping; Peptides; Phosphorylation; Plasmids; Polylysine; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-2; Recombinant Proteins; Threonine; Tumor Cells, Cultured; Tyrosine | 2000 |
Calcium-induced alterations in the functioning of protein serine/threonine and tyrosine kinases in Streptomyces fradiae cells.
Topics: Calcium; Cell Division; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Ions; Phosphorylation; Protein Denaturation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; Streptomyces; Threonine; Time Factors; Tyrosine | 2000 |
Topology and structure of the C1q-binding site on C-reactive protein.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; C-Reactive Protein; Complement Activation; Complement C1q; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylcholine; Polysaccharides, Bacterial; Serum Albumin, Bovine; Streptococcus pneumoniae; Threonine; Tyrosine | 2001 |
Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins.
Topics: Adenoviridae; Androstadienes; Animals; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Rats; Receptor, Insulin; Recombinant Proteins; Serine; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Wortmannin | 2001 |
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
Topics: Algorithms; Amino Acid Motifs; Amino Acid Sequence; Animals; Cattle; Databases, Factual; Genome; Humans; Internet; Mice; Molecular Sequence Data; Rats; Serine; Signal Transduction; Software; Threonine; Tyrosine | 2001 |
A systematic approach to the analysis of protein phosphorylation.
Topics: Amino Acid Sequence; Biochemistry; Caseins; Databases, Factual; Fungal Proteins; Gas Chromatography-Mass Spectrometry; Glucose; Glutathione Transferase; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Peptides; Phosphorylation; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Serine; Threonine; Time Factors; Tyrosine | 2001 |
Roles of amino acid residues near the chromophore of photoactive yellow protein.
Topics: Amino Acids; Bacterial Proteins; Glutamic Acid; Halorhodospira halophila; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Photolysis; Photoreceptors, Microbial; Protons; Spectrophotometry; Threonine; Titrimetry; Tyrosine | 2001 |
Isolation of hyperactive mutants of the MAPK p38/Hog1 that are independent of MAPK kinase activation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Enzyme Activation; Humans; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Rats; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Threonine; Tyrosine | 2001 |
Mutational and kinetic evaluation of conserved His-123 in dual specificity protein-tyrosine phosphatase vaccinia H1-related phosphatase: participation of Tyr-78 and Thr-73 residues in tuning the orientation of His-123.
Topics: Base Sequence; Conserved Sequence; DNA Primers; Dual-Specificity Phosphatases; Evaluation Studies as Topic; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Protein Tyrosine Phosphatases; Substrate Specificity; Threonine; Tyrosine | 2001 |
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates | 2001 |
Amelogenin-cytokeratin 14 interaction in ameloblasts during enamel formation.
Topics: Acetylglucosaminidase; Amelogenin; Animals; Binding Sites; Blotting, Western; Cells, Cultured; Dental Enamel; Dental Enamel Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Keratins; Kinetics; Mice; Microscopy, Confocal; Models, Biological; Mutation; Peptides; Proline; Protein Binding; Protein Structure, Tertiary; Protein Transport; Recombinant Proteins; Threonine; Time Factors; Tyrosine | 2001 |
Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor.
Topics: alpha 1-Antitrypsin; Animals; Binding Sites; Blotting, Western; Bronchoalveolar Lavage; Case-Control Studies; Catalytic Domain; Cathepsin B; Cathepsin L; Cathepsins; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Emphysema; Enzyme Activation; Enzyme Inhibitors; Epithelium; Female; Humans; Lung; Male; Middle Aged; Protein Binding; Proteinase Inhibitory Proteins, Secretory; Proteins; Recombinant Proteins; Secretory Leukocyte Peptidase Inhibitor; Threonine; Time Factors; Tyrosine | 2001 |
Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenoviridae; Amino Acids; Animals; Biological Transport; Carrier Proteins; Cell Cycle Proteins; Cell Line; Cysteine Endopeptidases; Cytosol; Deoxyglucose; Down-Regulation; Enzyme Inhibitors; Eukaryotic Initiation Factors; Glucose; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Sirolimus; Subcellular Fractions; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tyrosine | 2001 |
Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase.
Topics: Catalytic Domain; Circular Dichroism; Escherichia coli; Glucose; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Phosphotransferases (Phosphomutases); Threonine; Thymine Nucleotides; Tyrosine; UDPglucose 4-Epimerase; Xylose | 2001 |
Enteropathogenic Escherichia coli activates ezrin, which participates in disruption of tight junction barrier function.
Topics: Animals; Bacterial Adhesion; Cell Line; Cytoskeletal Proteins; Cytoskeleton; Escherichia coli; Escherichia coli Infections; Humans; Phosphoproteins; Phosphorylation; Signal Transduction; Threonine; Tight Junctions; Tyrosine; Virulence | 2001 |
The complete pathway for catalytic activation of the mitogen-activated protein kinase, ERK2.
Topics: Adenosine Triphosphate; Binding Sites; Catalysis; CDC2-CDC28 Kinases; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Enzyme Activation; Kinetics; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Threonine; Tyrosine | 2001 |
PDGF-BB-mediated activation of p42(MAPK) is independent of PDGF beta-receptor tyrosine phosphorylation.
Topics: Animals; Anticoagulants; Becaplermin; Benzoquinones; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Fibroblasts; Lactams, Macrocyclic; Lung; Male; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mutagenesis; Nitriles; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins c-sis; Quinones; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Rifabutin; Threonine; Transfection; Tyrosine; Tyrphostins | 2001 |
Solid-phase glycosylation of peptide templates and on-bead MAS-NMR analysis: perspectives for glycopeptide libraries.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Glycopeptides; Glycosylation; Indicators and Reagents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Serine; Threonine; Tyrosine | 2001 |
Electrochemical evaluation of the interfacial capacitance upon phosphorylation of amino acid analogue molecular films.
Topics: Amino Acids; Electrochemistry; Phosphorylation; Serine; Spectrophotometry, Infrared; Threonine; Tyrosine | 2001 |
Constitutive activation of extracellular signal-regulated kinase 2 by synergistic point mutations.
Topics: Amino Acid Sequence; Animals; Cell Line; Enzyme Activation; Humans; Mitogen-Activated Protein Kinase 1; Models, Molecular; Peptide Mapping; Phosphorylation; Point Mutation; Protein Conformation; Rats; Recombinant Proteins; Signal Transduction; Threonine; Tyrosine; X-Ray Diffraction | 2001 |
The linkage between beta1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of beta1 integrin in normal and cancerous human breast cells.
Topics: Actin Cytoskeleton; Actinin; Actins; Amino Acid Sequence; Breast; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Epithelial Cells; Female; Humans; Integrin beta1; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Serine; Threonine; Tumor Cells, Cultured; Tyrosine | 2001 |
The late-domain-containing protein p6 is the predominant phosphoprotein of human immunodeficiency virus type 1 particles.
Topics: Cell Line; Cyclin-Dependent Kinases; Endopeptidases; Enzyme Inhibitors; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Genistein; HIV-1; Humans; Kinetin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Purines; Serine; Threonine; Tyrosine; Virion | 2002 |
Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins.
Topics: Anisomycin; Cycloheximide; Genes, erbB; Genes, erbB-2; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Neuregulin-1; Phosphatidylinositol 3-Kinases; Phosphoproteins; Serine; Threonine; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association.
Topics: Animals; Butadienes; Cell Adhesion; Cell Line; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epithelial Cells; Escherichia coli; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Hepatocyte Growth Factor; Kidney Tubules; MAP Kinase Signaling System; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Nitriles; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Serine; Threonine; Time Factors; Tyrosine | 2002 |
Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases.
Topics: Agammaglobulinaemia Tyrosine Kinase; Blood Platelets; Blotting, Western; Calcium; Crotalid Venoms; Cytosol; Glutathione Transferase; Humans; Isoenzymes; Models, Biological; Myelin Basic Protein; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-theta; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; Serine; Serotonin; Signal Transduction; Threonine; Time Factors; Tyrosine | 2002 |
Contraction regulation of Akt in rat skeletal muscle.
Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Insulin; Morpholines; Muscle Contraction; Muscle, Skeletal; Phosphorylation; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Wortmannin | 2002 |
A 45-kDa protein kinase related to mitogen-activated protein kinase is activated in tobacco cells treated with a phorbol ester.
Topics: Cells, Cultured; Cycloheximide; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Weight; Nicotiana; Phosphorylation; Plant Proteins; Serine; Stress, Mechanical; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2002 |
The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status.
Topics: Amino Acid Sequence; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA; Dopamine beta-Hydroxylase; Electrophoresis, Gel, Two-Dimensional; Genes, Reporter; Homeodomain Proteins; Humans; Models, Biological; Molecular Sequence Data; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine | 2002 |
Threonine-124 and phenylalanine-448 in Citrobacter freundii tyrosine phenol-lyase are necessary for activity with L-tyrosine.
Topics: Amino Acid Sequence; Binding Sites; Citrobacter freundii; Escherichia coli; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Sequence Alignment; Structure-Activity Relationship; Threonine; Tyrosine; Tyrosine Phenol-Lyase | 2002 |
Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Blood Proteins; Casein Kinase II; Caspase 3; Caspases; Cell Death; Cell Survival; Cytochrome c Group; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Humans; Jurkat Cells; Phosphorylation; Poly(ADP-ribose) Polymerases; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Serine; Threonine; Time Factors; Triazoles; Tyrosine | 2002 |
Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms.
Topics: Amino Acids; Animals; Biological Transport; Glucose; Glycogen Synthase Kinase 3; Heart; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Metabolism; Mitogen-Activated Protein Kinases; Myocardium; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Threonine; Tyrosine | 2002 |
D1 dopamine receptor regulation of microtubule-associated protein-2 phosphorylation in developing cerebral cortical neurons.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Dendrites; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Frontal Lobe; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neurites; Neurons; Phosphorylation; Receptors, Dopamine D1; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine | 2002 |
Regulation of phospholipase C-gamma1 by protein kinase A-dependent phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; COS Cells; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Gene Expression Regulation, Enzymologic; Immunoblotting; Isoenzymes; Ligands; Mice; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipase C gamma; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Rats; Receptors, Adrenergic, beta-2; Serine; Threonine; Time Factors; Transfection; Type C Phospholipases; Tyrosine | 2002 |
Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63.
Topics: Amino Acid Sequence; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Biological Transport; Cell Line; Cell Membrane; Electrophysiology; Green Fluorescent Proteins; Humans; Hydrogen-Ion Concentration; Ions; Isoleucine; Luminescent Proteins; Microscopy, Fluorescence; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nitrates; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Software; Threonine; Transfection; Tyrosine; Xenopus laevis | 2002 |
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Adhesion; CHO Cells; Cricetinae; Fucosyltransferases; Glycosylation; Membrane Glycoproteins; Mice; Mutagenesis, Site-Directed; N-Acetylglucosaminyltransferases; P-Selectin; Protein Binding; Sulfates; Threonine; Transfection; Tyrosine | 2003 |
Evidence for a direct interaction between the Thr11 residue of vasoactive intestinal polypeptide and Tyr184 located in the first extracellular loop of the VPAC2 receptor.
Topics: Adenylyl Cyclases; Cell Line; Cell Membrane; Gastrointestinal Agents; Hydrogen Bonding; Peptide Fragments; Protein Binding; Protein Conformation; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Peptide, Type II; Recombinant Fusion Proteins; Threonine; Tyrosine; Vasoactive Intestinal Peptide | 2003 |
Fibroblast growth factor-2-induced signaling through lipid raft-associated fibroblast growth factor receptor substrate 2 (FRS2).
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Brain; Detergents; Enzyme Activation; Fibroblast Growth Factor 2; Humans; Lipid Metabolism; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Microdomains; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Octoxynol; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Serine; Signal Transduction; Threonine; Time Factors; Tumor Cells, Cultured; Tyrosine | 2003 |
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine | 2003 |
Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 1. Kinetic evidence for cooperative effects associated with the binding of inorganic phosphate and the 5'-phosphate moiety of the cofactor.
Topics: Alanine; Apoproteins; Asparagine; Binding Sites; Desulfovibrio vulgaris; Flavin Mononucleotide; Flavodoxin; Histidine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Phosphates; Protein Binding; Riboflavin; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tryptophan; Tyrosine | 2003 |
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
Topics: 3T3 Cells; Adenoviridae; Animals; Cell Division; Cell Line; Cloning, Molecular; COS Cells; Enzyme Activation; Fibroblast Growth Factors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Serine; Signal Transduction; Threonine; Thymidine; Tyrosine | 2003 |
Nitric oxide regulates the phosphorylation of the threonine-glutamine-tyrosine motif in proteins of human spermatozoa during capacitation.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Motifs; Arginine; Bucladesine; Drug Combinations; Enzyme Inhibitors; Glutamine; Humans; Immunologic Techniques; Male; Molecular Weight; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen Oxides; Phosphorylation; Proteins; Sperm Capacitation; Spermatozoa; Spermine; Threonine; Tyrosine | 2003 |
Tissue-specific impairment of insulin signaling in vasculature and skeletal muscle of fructose-fed rats.
Topics: Animals; Aorta, Thoracic; Dietary Sucrose; Fructose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phosphoproteins; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Threonine; Tyrosine | 2003 |
An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro.
Topics: Catalytic Domain; Cells, Cultured; Enzyme Activation; Glutathione Transferase; Humans; Mitogen-Activated Protein Kinase 7; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Peptide Fragments; Phosphorylation; Recombinant Fusion Proteins; Threonine; Trypsin; Tyrosine | 2003 |
Phosphorylation of Tyr-176 of the yeast MAPK Hog1/p38 is not vital for Hog1 biological activity.
Topics: Catalysis; Gene Expression Regulation; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Osmotic Pressure; Phosphorylation; Protein Conformation; Saccharomyces cerevisiae Proteins; Sodium Chloride; Threonine; Tyrosine | 2003 |
Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits low density lipoprotein-induced signaling in platelets.
Topics: Amino Acid Motifs; Blood Platelets; Blotting, Western; Cross-Linking Reagents; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Peptides; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; Threonine; Time Factors; Tyrosine; Vanadates | 2003 |
Synergistic growth inhibitory effects of interferon-alpha and lovastatin on bcr-abl positive leukemic cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon alpha-2; Interferon-alpha; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lovastatin; Mevalonic Acid; Phosphorylation; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Recombinant Proteins; Serine; Threonine; Time Factors; Tyrosine | 2003 |
Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins.
Topics: 14-3-3 Proteins; 3T3 Cells; Amino Acid Motifs; Animals; Cell Line; Cloning, Molecular; DNA-Binding Proteins; Genetic Vectors; Glutathione Transferase; Humans; Ligands; MAP Kinase Signaling System; Mice; Milk Proteins; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Okadaic Acid; Phosphorylation; Phosphoserine; Phosphothreonine; Plasmids; Precipitin Tests; Prolactin; Protein Binding; Protein Isoforms; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Prolactin; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Threonine; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
Combination of two activating mutations in one HOG1 gene forms hyperactive enzymes that induce growth arrest.
Topics: Catalysis; Cell Division; Enzyme Activation; Gene Expression Regulation, Fungal; Mitogen-Activated Protein Kinases; Mutation; Osmotic Pressure; Phosphorylation; Promoter Regions, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Tyrosine | 2003 |
High-resolution solution structure of the beryllofluoride-activated NtrC receiver domain.
Topics: Bacterial Proteins; Beryllium; Binding Sites; Crystallography, X-Ray; DNA-Binding Proteins; Fluorides; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; PII Nitrogen Regulatory Proteins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Solutions; Threonine; Trans-Activators; Transcription Factors; Tyrosine | 2003 |
[Distinctive infrared spectral features in human breast cancer].
Topics: Breast Neoplasms; Female; Glycogen; Humans; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2000 |
EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; COS Cells; ErbB Receptors; Feedback, Physiological; Humans; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Receptors, Fibroblast Growth Factor; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Threonine; Tyrosine | 2003 |
Phenylalanine as an amino acid antagonist for the rat.
Topics: Amino Acids; Animals; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine | 1956 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
Partial purification of the threonine- and tyrosine-activating enzymes from rat liver, and the effect of patassium ions on the activity of the tyrosine enzyme.
Topics: Enzyme Activators; Enzymes; Ions; Liver; Potassium; Threonine; Tyrosine | 1961 |
Effectiveness of urea and ammonium nitrogen for the synthesis of dispensable amino acids by the chick.
Topics: Amino Acids; Ammonium Compounds; Animals; Arginine; Chickens; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Quaternary Ammonium Compounds; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
Nitrogen balance studies with subjects fed the essential amino acids in plasma pattern proportions.
Topics: Amino Acids, Essential; Cystine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
A DETERMINATION OF THE ESSENTIAL AMINO ACID PROPORTIONS NEEDED TO ALLOW RAPID GROWTH IN CHICKS.
Topics: Amino Acids; Amino Acids, Essential; Animals; Animals, Newborn; Arginine; Caseins; Chickens; Cystine; Diet; Dietary Proteins; Glutamates; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Poultry; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
RELATIVE POTENCY OF DIETS CONTAINING AMINO ACIDS AND PROTEINS FOR PROMOTING GROWTH OF RATS.
Topics: Albumins; Amino Acids; Animals, Newborn; Arginine; Cystine; Diet; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Rats; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE AMINO ACIDS COMPOSITION AND NUTRITIVE VALUE OF PROTEINS. V. AMINO ACID REQUIREMENTS AS A PATTERN FOR PROTEIN EVALUATION.
Topics: Albumins; Amino Acids; Caseins; Cystine; Dietary Proteins; Gelatin; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Physiological Phenomena; Nutritional Sciences; Nutritive Value; Ovalbumin; Phenylalanine; Proteins; Rats; Research; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
HEPATOMAS IN TISSUE CULTURE COMPARED WITH ADAPTING LIVER IN VIVO.
Topics: Carcinoma, Hepatocellular; Glucosephosphate Dehydrogenase; Hydro-Lyases; Liver; Liver Neoplasms; Ornithine; Oxidoreductases; Oxygenases; Phosphotransferases; Proteins; RNA; Threonine; Tissue Culture Techniques; Transaminases; Transferases; Tryptophan; Tyrosine | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
ENDOGENOUS RENAL CLEARANCES OF 12 INDIVIDUAL AMINO ACIDS IN FOUR APPARENTLY HEALTHY SUBJECTS AND IN FOUR AMINOACIDURIC PERSONS OF A KINDRED WITH HEREDITARY PANCREATITIS.
Topics: Amino Acids; Arginine; Biomedical Research; Cystine; Genetics, Medical; Glutamates; Healthy Volunteers; Histidine; Isoleucine; Kidney; Leucine; Lysine; Methionine; Pancreatitis; Pancreatitis, Chronic; Phenylalanine; Physiology; Renal Aminoacidurias; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[ON THE HORMONAL REGULATION OF PROTEIN METABOLISM. THE EFFECT ON INSULIN AND GLUCAGON].
Topics: Alanine; Arginine; Aspartic Acid; Blood Glucose; Carbohydrate Metabolism; Glucagon; Glutamates; Glycine; Histidine; Insulin; Leucine; Lysine; Pharmacology; Phenylalanine; Proteins; Threonine; Tyrosine; Valine | 1964 |
UROLITHIASIS IN THE RAT. IV. INFLUENCE OF AMINO ACID SUPPLEMENTS ON THE OCCURRENCE OF CITRATE CALCULI.
Topics: Amino Acids; Calcium; Caseins; Citrates; Citric Acid; Cystine; Dietary Proteins; Glutamates; Isoleucine; Kidney Calculi; Leucine; Lysine; Methionine; Phenylalanine; Proteins; Rats; Research; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
SOME PROPERTIES OF METHANOBACTERIUM OMELIANSKII FERREDOXIN.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacteria; Chemistry Techniques, Analytical; Cystine; Ferredoxins; Glutamates; Glycine; Iron; Lysine; Methanobacterium; Proline; Serine; Spectrophotometry; Sulfides; Threonine; Tyrosine; Valine | 1964 |
PLASMA AMINO ACIDS AFTER BIRTH.
Topics: Amino Acids; Chromatography; Dietary Proteins; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Ion Exchange; Lysine; Parturition; Taurine; Threonine; Tyrosine | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
EFFECT OF GLUCOSE INFUSION ON THE INDIVIDUAL PLASMA FREE AMINO ACIDS IN MAN.
Topics: Amino Acids; Blood; Glucose; Humans; Insulin; Isoleucine; Leucine; Male; Pharmacology; Phenylalanine; Threonine; Tyrosine; Valine | 1964 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
TRIFLUROACETYLATED AMINO ACID ESTERS: THE STABILITY OF THE DERIVATIVES OF CYSTEINE, HYDROXYPROLINE, SERINE, THREONINE AND TYROSINE.
Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Esters; Hydroxyproline; Research; Serine; Threonine; Tyrosine | 1965 |
RELATION OF BIOCHEMICAL MUTATIONS TO ACTINOMYCIN SYNTHESIS IN STREPTOMYCES ANTIBIOTICUS.
Topics: Adenine; Amino Acids; Arginine; Culture Media; Cysteine; Dactinomycin; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Mutation; Phenylalanine; Research; Streptomyces; Streptomyces antibioticus; Threonine; Tyrosine; Ultraviolet Rays; Uracil; Valine | 1965 |
BITTER PEPTIDE ISOLATED FROM MILK CULTURES OF STREPTOCOCCUS CREMORIS.
Topics: Alanine; Amino Acids; Arginine; Butanones; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Culture Media; Electrophoresis; Glutamates; Glycine; Histidine; Indicators and Reagents; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Milk; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Research; Streptococcus; Threonine; Tyrosine; Valine | 1965 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
THE READ-OUT OF TURNIP YELLOW MOSAIC VIRUS RIBONUCLEIC ACID AS A POLYCISTRONIC MESSENGER IN CELL-FREE SYSTEMS OF ESCHERICHIA COLI.
Topics: Cell-Free System; Escherichia coli; Genetic Code; Kinetics; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Plant Viruses; Proteins; Research; Ribosomes; RNA; RNA, Messenger; RNA, Viral; Serine; Threonine; Tymovirus; Tyrosine | 1965 |
AMINO ACID SENSITIVITY OF STRAINS DERIVED FROM ESCHERICHIA COLI K 12.
Topics: Amino Acids; Bacteriological Techniques; Escherichia coli; Feedback; Genetics; Glycine; Growth; Isoleucine; Leucine; Methionine; Pharmacology; Proline; Research; Serotonin; Threonine; Tyrosine; Valine | 1965 |
The specific amino acid requirements of a human carcinoma cell (Stain HeLa) in tissue culture.
Topics: Amino Acids; Animals; Arginine; Coloring Agents; Female; HeLa Cells; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Neoplasms, Experimental; Phenylalanine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Uterine Neoplasms; Uterus; Valine | 1955 |
Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells.
Topics: Allopurinol; Animals; Arsenicals; Chelating Agents; Cross-Linking Reagents; Cytoskeletal Proteins; Deferoxamine; Detergents; Dimethyl Sulfoxide; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Humans; Intercellular Adhesion Molecule-1; Intracellular Signaling Peptides and Proteins; Lung; Mice; Microcirculation; Mitogen-Activated Protein Kinases; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Phosphatase 2; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Reactive Oxygen Species; Recombinant Proteins; Signal Transduction; src-Family Kinases; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Xanthine Oxidase | 2003 |
Phosphorylations of cyclin-dependent kinase 2 revisited using two-dimensional gel electrophoresis.
Topics: Adenosine Triphosphate; Blotting, Western; CDC2-CDC28 Kinases; cdc25 Phosphatases; Cell Cycle; Cell Line; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Electrophoresis, Gel, Two-Dimensional; G1 Phase; Humans; Mitogens; Models, Biological; Phosphorylation; Precipitin Tests; Protein Binding; S Phase; Threonine; Time Factors; Tyrosine | 2003 |
Molecular determinants of proton modulation of glycine receptors.
Topics: Amino Acid Sequence; Binding, Competitive; Carrier Proteins; Cell Line; Dimerization; Dose-Response Relationship, Drug; Electrophysiology; Glycine; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Neurons; Protein Structure, Tertiary; Protons; Receptors, GABA-A; Receptors, Glycine; Sequence Homology, Amino Acid; Strychnine; Threonine; Tyrosine | 2004 |
1,10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus oocytes.
Topics: Animals; Blotting, Western; Butadienes; Cell-Free System; Chromones; Colforsin; Cycloheximide; Enzyme Inhibitors; Female; Flavonoids; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Pentetic Acid; Phenanthrolines; Phosphorylation; Progesterone; Threonine; Tyrosine; Xenopus laevis; Zinc Sulfate | 2003 |
Cloning and characterization of a GABAA receptor gamma2 subunit variant.
Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cell Membrane; Cloning, Molecular; Exons; Glycine; Humans; Immunohistochemistry; Introns; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Proteins; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Threonine; Tissue Distribution; Transfection; Tyrosine | 2004 |
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
Topics: Acetylglucosamine; Active Transport, Cell Nucleus; Alanine; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; CREB-Binding Protein; Cytoplasm; Dimerization; DNA-Binding Proteins; Epithelial Cells; Galactosyltransferases; Glycosylation; Growth Substances; Humans; Insecta; Interferons; Lectins; Ligands; Luciferases; Mass Spectrometry; Microscopy, Fluorescence; Milk Proteins; Mutation; Nuclear Proteins; Phosphorylation; Prolactin; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine; STAT5 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
Expression of phosphorylation of N-methyl-D-aspartate receptor subunits during graded hypoxia in the cerebral cortex of newborn piglets.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Hypoxia; Phosphocreatine; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Serine; Swine; Threonine; Tyrosine | 2004 |
Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Carotenoids; Deuterium Oxide; Halorhodopsins; Hydrogen Bonding; Natronobacterium; Phenylalanine; Photoreceptors, Microbial; Sensory Rhodopsins; Serine; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2003 |
Tyrosine 105 and threonine 212 at outermost substrate binding subsites -6 and +4 control substrate specificity, oligosaccharide cleavage patterns, and multiple binding modes of barley alpha-amylase 1.
Topics: alpha-Amylases; Amino Acid Sequence; Binding Sites; Catalytic Domain; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hordeum; Hydrogen Bonding; Hydrolysis; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligosaccharides; Peptides; Pichia; Plasmids; Protein Binding; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 2004 |
Poly-L-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium.
Topics: Animals; Arginine; Cell Membrane Permeability; In Vitro Techniques; Male; Membrane Proteins; Nasal Mucosa; Occludin; Peptides; Phosphoproteins; Phosphorylation; Rabbits; Serine; Threonine; Tyrosine; Zonula Occludens-1 Protein | 2003 |
Physical and functional interactions between vaccinia virus F10 protein kinase and virion assembly proteins A30 and G7.
Topics: Animals; Cell Line; Gene Expression Regulation, Viral; HeLa Cells; Humans; Microscopy, Confocal; Microscopy, Immunoelectron; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Rabbits; Threonine; Tyrosine; Vaccinia virus; Viral Core Proteins; Viral Envelope Proteins; Viral Proteins; Virion; Virus Assembly | 2004 |
Site-directed mutagenesis of NnrR: a transcriptional regulator of nitrite and nitric oxide reductase in Rhodobacter sphaeroides.
Topics: Bacterial Proteins; Environment; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Immunoblotting; Mutagenesis, Site-Directed; Nitrite Reductases; Oxidoreductases; Promoter Regions, Genetic; Rhodobacter sphaeroides; Threonine; Trans-Activators; Transcription, Genetic; Tyrosine | 2003 |
Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells.
Topics: Adaptor Proteins, Signal Transducing; Adherens Junctions; Binding Sites; Blotting, Western; Caco-2 Cells; Cadherins; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Line; Cytoskeleton; Discs Large Homolog 1 Protein; Epithelial Cells; Genes, Reporter; Humans; Intestinal Mucosa; Intestines; Luciferases; Membrane Proteins; Microscopy, Fluorescence; Models, Genetic; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serine; Signal Transduction; src Homology Domains; Subcellular Fractions; Threonine; Transfection; Tyrosine; Zonula Occludens-1 Protein | 2004 |
Methotrexate induces interleukin-8 production by human bronchial and alveolar epithelial cells.
Topics: Acetylcysteine; Bronchi; Cell Line; Cycloheximide; Epithelial Cells; Folic Acid Antagonists; Free Radical Scavengers; Glucose; Humans; Hypoglycemia; Interleukin-1; Interleukin-8; Lipopolysaccharides; Methotrexate; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pulmonary Alveoli; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Crystal structure of a cAMP-dependent protein kinase mutant at 1.26A: new insights into the catalytic mechanism.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cyclic AMP-Dependent Protein Kinases; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Threonine; Tyrosine | 2004 |
Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke.
Topics: Animals; Blotting, Northern; Butadienes; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Immunoblotting; Immunohistochemistry; Lung; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; RNA, Messenger; Signal Transduction; Smoking; Threonine; Time Factors; Tyrosine; Up-Regulation | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation.
Topics: Active Transport, Cell Nucleus; Binding Sites; Blotting, Western; cdc25 Phosphatases; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Chromatography, Gel; Cyclin B; Glutathione Transferase; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Confocal; Mitosis; Mutagenesis, Site-Directed; Phosphorylation; Plasmids; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Transport; Recombinant Fusion Proteins; RNA, Messenger; RNA, Small Interfering; Serine; Subcellular Fractions; Threonine; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
Resonance Raman spectroscopy reveals the origin of an intermediate wavelength form in photoactive yellow protein.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Deuterium Exchange Measurement; Glutamic Acid; Glutamine; Kinetics; Phenylalanine; Photoreceptors, Microbial; Quantum Theory; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thermodynamics; Thiocyanates; Threonine; Tyrosine; Valine | 2004 |
Molecular determinants of vanilloid sensitivity in TRPV1.
Topics: Amino Acid Sequence; Animals; Calcium; Capsaicin; Cations; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Ganglia, Spinal; Hot Temperature; Humans; Hydrogen-Ion Concentration; In Situ Hybridization; Inhibitory Concentration 50; Ligands; Methionine; Models, Molecular; Molecular Sequence Data; Mutation; Neurons; Phorbol Esters; Phylogeny; Protein Binding; Protein Structure, Tertiary; Protons; Rabbits; Rats; Receptors, Drug; Sequence Homology, Amino Acid; Serine; Temperature; Threonine; Transfection; Tyrosine | 2004 |
MAP kinase-like activity in transformed Catharanthus roseus hairy roots varies with culture conditions such as temperature and hypo-osmotic shock.
Topics: Adaptation, Physiological; Amino Acid Motifs; Catharanthus; Culture Media; Culture Techniques; Mitogen-Activated Protein Kinases; Molecular Weight; Myelin Basic Protein; Osmolar Concentration; Osmotic Pressure; Peptides; Phosphorylation; Plant Roots; Precipitin Tests; Temperature; Threonine; Time Factors; Tyrosine | 2004 |
The crystal structure of the Y66L variant of green fluorescent protein supports a cyclization-oxidation-dehydration mechanism for chromophore maturation.
Topics: Amino Acid Substitution; Animals; Crystallization; Crystallography, X-Ray; Genetic Variation; Green Fluorescent Proteins; Heterocyclic Compounds; Hydrogen Bonding; Imidazoles; Leucine; Luminescent Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Protein Precursors; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tyrosine | 2004 |
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anisomycin; Anthracenes; Brain; Cell Line; Cell Line, Tumor; COS Cells; Down-Regulation; Enzyme Inhibitors; Estradiol; Flavonoids; Genetic Vectors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Neurons; Oxidoreductases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retroviridae; RNA, Small Interfering; Serine; tau Proteins; Temperature; Threonine; Time Factors; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Tyrosine; WW Domain-Containing Oxidoreductase | 2004 |
Bacterially expressed recombinant p68 RNA helicase is phosphorylated on serine, threonine, and tyrosine residues.
Topics: Blotting, Western; DEAD-box RNA Helicases; Escherichia coli; Phosphorylation; Protein Kinases; Recombinant Proteins; RNA Helicases; Serine; Threonine; Tyrosine | 2004 |
How oligomerization contributes to the thermostability of an archaeon protein. Protein L-isoaspartyl-O-methyltransferase from Sulfolobus tokodaii.
Topics: Amino Acid Sequence; Archaea; Aspartic Acid; Calorimetry, Differential Scanning; Circular Dichroism; Crystallography, X-Ray; Dose-Response Relationship, Drug; Gene Deletion; Genetic Vectors; Guanidine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Structure, Secondary; Protein Structure, Tertiary; S-Adenosylmethionine; Sequence Homology, Amino Acid; Sulfolobus; Temperature; Threonine; Tyrosine; Valine; X-Ray Diffraction | 2004 |
Altered activity of signaling pathways in diaphragm and tibialis anterior muscle of dystrophic mice.
Topics: Animals; Diaphragm; Extremities; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Muscular Dystrophy, Animal; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Threonine; Tyrosine | 2004 |
The Phosphorylation Site Database: A guide to the serine-, threonine-, and/or tyrosine-phosphorylated proteins in prokaryotic organisms.
Topics: Archaea; Bacteria; Databases, Factual; Internet; Phosphoproteins; Prokaryotic Cells; Serine; Threonine; Tyrosine | 2004 |
Kinetic studies of Thermobifida fusca Cel9A active site mutant enzymes.
Topics: Actinomycetales; Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Carboxymethylcellulose Sodium; Cellulase; Enzyme Activation; Fibronectins; Glutamic Acid; Kinetics; Leucine; Lysine; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Substrate Specificity; Threonine; Tyrosine | 2004 |
[The weight of epidemiologic studies].
Topics: Adolescent; Adult; Algorithms; Animals; Case-Control Studies; Child; Cholesterol; Cohort Studies; Cross-Sectional Studies; Epidemiologic Studies; Female; Humans; Male; Middle Aged; Migraine Disorders; Mucoproteins; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Surveys and Questionnaires; Threonine; Tryptophan; Tyrosine | 2004 |
Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
Topics: Asparagine; Bacillus cereus; Bacterial Proteins; beta-Amylase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Maltose; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Plant Proteins; Threonine; Tyrosine | 2004 |
Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin. Insights into molecular coevolution of V1a type receptors and their ligands.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine Vasopressin; Binding Sites; Gene Expression; Genes, fos; Humans; Isoleucine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phenylalanine; Proline; Promoter Regions, Genetic; Rana catesbeiana; Rats; Receptors, Vasopressin; Recombinant Fusion Proteins; Structure-Activity Relationship; Threonine; Transfection; Tyrosine; Vasotocin | 2004 |
IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Catalysis; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; HeLa Cells; Humans; Insulin-Like Growth Factor I; Models, Biological; Multienzyme Complexes; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Threonine; Transfection; Tumor Suppressor Proteins; Tyrosine | 2004 |
Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization.
Topics: Adenylyl Cyclases; Animals; Arrestins; beta-Arrestins; Cell Line; Cyclic AMP; Dimerization; Electrophoresis, Polyacrylamide Gel; Endocytosis; Female; Heparin; Humans; Immunoprecipitation; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Muscle Cells; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Polymerase Chain Reaction; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Corticotropin-Releasing Hormone; Serine; Sheep; Signal Transduction; Threonine; Time Factors; Transfection; Tyrosine | 2005 |
Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling.
Topics: Active Transport, Cell Nucleus; Blotting, Western; Cell Line; Cell Nucleus; Chromatin Immunoprecipitation; Dimerization; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Humans; Immunoprecipitation; Membrane Glycoproteins; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Structure, Tertiary; Receptors, Cell Surface; RNA, Double-Stranded; RNA, Small Interfering; Signal Transduction; Threonine; Toll-Like Receptor 3; Toll-Like Receptors; Tyrosine | 2004 |
Serine/threonine/tyrosine phosphorylation of the LHX3 LIM-homeodomain transcription factor.
Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Gel, Two-Dimensional; Homeodomain Proteins; Humans; LIM-Homeodomain Proteins; Molecular Sequence Data; Phosphorylation; Sequence Homology, Amino Acid; Serine; Threonine; Transcription Factors; Tyrosine | 2005 |
Following in vitro activation of mitogen-activated protein kinases by mass spectrometry and tryptic peptide analysis: purifying fully activated p38 mitogen-activated protein kinase alpha.
Topics: Amino Acid Sequence; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Enzyme Activation; Escherichia coli; Histidine; MAP Kinase Kinase 6; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Threonine; Trypsin; Tyrosine | 2005 |
Detection of the site of phosphorylation in a peptide using Raman spectroscopy and partial least squares discriminant analysis.
Topics: Humans; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Serine; Spectrum Analysis, Raman; Threonine; Tyrosine | 2005 |
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.
Topics: Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; Cell Line, Tumor; Checkpoint Kinase 2; Cyclin B; Cyclin B1; DNA Damage; Escherichia coli; G2 Phase; Glutathione Transferase; HeLa Cells; Humans; Immunoprecipitation; Models, Biological; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Radiation, Ionizing; Recombinant Fusion Proteins; RNA, Small Interfering; Signal Transduction; Threonine; Transfection; Tumor Suppressor Protein p53; Two-Hybrid System Techniques; Tyrosine; Ultraviolet Rays | 2005 |
The mechanism of inhibition of the cyclin-dependent kinase-2 as revealed by the molecular dynamics study on the complex CDK2 with the peptide substrate HHASPRK.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Binding Sites; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; Humans; Ions; Magnesium; Models, Molecular; Peptides; Phosphates; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Software; Stereoisomerism; Threonine; Time Factors; Tyrosine; X-Rays | 2005 |
Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.
Topics: Alanine; Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Genes, Suppressor; Genetic Testing; Mating Factor; Molecular Sequence Data; Mutagenesis; Peptides; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2005 |
Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Nucleus; Circular Dichroism; Cloning, Molecular; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor Proteins; Dose-Response Relationship, Drug; Dual-Specificity Phosphatases; Escherichia coli; Humans; Ions; Kinetics; Membrane Proteins; Models, Biological; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Recombinant Proteins; Sequence Homology, Amino Acid; Threonine; Time Factors; Tyrosine | 2005 |
Proton pathways in green fluorescence protein.
Topics: Animals; Aspartic Acid; Binding Sites; Biophysics; Crystallography, X-Ray; Cytoplasm; Databases, Protein; Glutamic Acid; Glutamine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Light; Lysine; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Point Mutation; Protein Conformation; Protons; Scyphozoa; Solvents; Spectrophotometry; Threonine; Time Factors; Tyrosine; Water; X-Rays | 2005 |
Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; Biomarkers; Body Patterning; Catalytic Domain; Chromosome Mapping; Drosophila; Embryo, Nonmammalian; ErbB Receptors; Exons; Feedback, Physiological; Gene Expression Regulation, Developmental; Introns; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Structure, Tertiary; ras Proteins; Receptors, Fibroblast Growth Factor; Sequence Homology, Amino Acid; Signal Transduction; Threonine; Tyrosine; Veins; Wings, Animal; Xenopus | 2005 |
Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation.
Topics: Alanine; Amino Acid Substitution; Animals; Antigen Presentation; Arginine; Cell Line; Cell Line, Tumor; Endoplasmic Reticulum; Epitopes; Glutamine; Histocompatibility Antigens Class I; Intracellular Fluid; Melanoma; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Peptide Fragments; Proteasome Endopeptidase Complex; Protein Folding; Protein Processing, Post-Translational; Protein Transport; Substrate Specificity; Threonine; Transfection; Tyrosine | 2005 |
Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; In Vitro Techniques; Mice; Models, Biological; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; src-Family Kinases; Threonine; Thrombin; Type C Phospholipases; Tyrosine | 2005 |
The Pro33 isoform of integrin beta3 enhances outside-in signaling in human platelets by regulating the activation of serine/threonine phosphatases.
Topics: Blood Platelets; Densitometry; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Immunoblotting; Integrin beta3; Leucine; Mitogen-Activated Protein Kinase 1; Models, Biological; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphorylation; Platelet Adhesiveness; Polymorphism, Genetic; Proline; Protein Isoforms; Protein Serine-Threonine Kinases; Signal Transduction; Threonine; Tyrosine | 2005 |
Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation.
Topics: Amino Acid Sequence; Animals; Biotin; Blood Platelets; Blotting, Western; Cell Communication; Cell Line; Cloning, Molecular; COS Cells; Cross-Linking Reagents; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Epidermal Growth Factor; Eptifibatide; Flow Cytometry; Humans; Immunoprecipitation; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Peptides; Peroxidase; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Tissue Distribution; Transfection; Tyrosine | 2005 |
Signaling to the DEAD box--regulation of DEAD-box p68 RNA helicase by protein phosphorylations.
Topics: DEAD-box RNA Helicases; HeLa Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Pyridines; RNA Helicases; Signal Transduction; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Critical amino acid residues of the common allosteric site on the M2 muscarinic acetylcholine receptor: more similarities than differences between the structurally divergent agents gallamine and bis(ammonio)alkane-type hexamethylene-bis-[dimethyl-(3-phtha
Topics: Allosteric Site; Amino Acid Sequence; Gallamine Triethiodide; Humans; Isoindoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Phthalimides; Protein Conformation; Receptor, Muscarinic M2; Sequence Homology, Amino Acid; Threonine; Tyrosine | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
Short communication: Amino acids antagonistic to the amino acids inhibitory for growth rate of mixed ruminal bacteria.
Topics: Amino Acids; Animals; Bacteria; Cattle; Diet; Feedback, Physiological; Female; Fermentation; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Threonine; Tryptophan; Tyrosine; Valine | 2005 |
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Topics: Animals; Cell Line; Drosophila Proteins; Dyrk Kinases; Insecta; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 2005 |
p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells.
Topics: Animals; CDC2-CDC28 Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; G1 Phase; Hypoglycemic Agents; Imidazoles; Insulin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; S Phase; Signal Transduction; Threonine; Thyroid Gland; Tyrosine | 2005 |
Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells.
Topics: Anti-Bacterial Agents; Azithromycin; Bronchi; Cells, Cultured; Clarithromycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reference Values; Threonine; Time Factors; Tyrosine | 2006 |
Protein tyrosine phosphorylation, hyperactivation and progesterone-induced acrosome reaction are enhanced in IVF media: an effect that is not associated with an increase in protein kinase A activation.
Topics: Acrosome Reaction; Culture Media; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Enzyme Activation; Fertilization in Vitro; Humans; Male; Phosphorylation; Progesterone; Serine; Sperm Capacitation; Spermatozoa; Threonine; Tyrosine | 2005 |
Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II.
Topics: Atherosclerosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalysis; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Epidermal Growth Factor; ErbB Receptors; Humans; Inflammation; Models, Biological; Mutation; Nitric Oxide; Nitric Oxide Synthase Type III; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Receptor, PAR-1; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; src-Family Kinases; Threonine; Thrombin; Thrombomodulin; Time Factors; Tyrosine; Umbilical Veins | 2005 |
Substrate specificity and activity regulation of protein kinase MELK.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Binding Sites; Buffers; Calcium; Cell Cycle; Cell Line; Chlorocebus aethiops; COS Cells; Dithiothreitol; Enzyme Activation; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glutathione; Humans; Ions; Kinetics; Ligands; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphorylation; Protein Array Analysis; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; RNA, Messenger; Serine; Stem Cells; Substrate Specificity; Threonine; Tyrosine | 2005 |
Purification and characterization of spiralin, the main protein of the Spiroplasma citri membrane.
Topics: Alanine; Bacterial Outer Membrane Proteins; Biochemistry; Buffers; Cell Membrane; Detergents; Electrophoresis; Electrophoresis, Agar Gel; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycine; Histidine; Immunoelectrophoresis; Intracellular Membranes; Leucine; Methionine; Molecular Weight; Phenylalanine; Sepharose; Spiroplasma citri; Subcellular Fractions; Threonine; Tryptophan; Tyrosine; Valine | 1977 |
Paxillin phosphorylation sites mapped by mass spectrometry.
Topics: Animals; Cell Line; Chickens; Chromatography, High Pressure Liquid; Humans; Mice; Paxillin; Phosphorylation; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Transfection; Tyrosine | 2005 |
FAK phosphorylation sites mapped by mass spectrometry.
Topics: Amino Acid Sequence; Animals; Cell Line; Chickens; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tyrosine | 2005 |
Identification of constitutive phosphorylation sites on the Epstein-Barr virus ZEBRA protein.
Topics: Binding Sites; Biochemistry; Cell Line, Tumor; Cell Movement; Cysteine; DNA-Binding Proteins; Escherichia coli; Genetic Vectors; Herpesvirus 4, Human; Humans; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Methionine; Mutagenesis; Peptides; Phosphorylation; Protein Structure, Tertiary; Serine; Threonine; Trans-Activators; Transfection; Trypsin; Tyrosine; Viral Proteins | 2006 |
Low-dose exposure of intestinal epithelial cells to formaldehyde results in MAP kinase activation and molecular alteration of the focal adhesion protein paxillin.
Topics: Alkaline Phosphatase; Blotting, Western; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; HT29 Cells; Humans; Immunoprecipitation; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Paxillin; Phosphorylation; Serine; Signal Transduction; Threonine; Tyrosine | 2006 |
A role of PP1/PP2A in mesenteric lymph node T cell suppression in a two-hit rodent model of alcohol intoxication and injury.
Topics: Alcoholic Intoxication; Animals; Binding Sites; Burns; Cytokines; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Ethanol; Immune Tolerance; Lymph Nodes; Male; MAP Kinase Signaling System; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Threonine; Tyrosine | 2006 |
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine | 2006 |
Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics.
Topics: Cell Cycle Proteins; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Humans; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Conformation; Nerve Tissue Proteins; Phosphorylation; Phylogeny; Protein Conformation; Protein Kinase Inhibitors; Protein Structure, Secondary; Protein Structure, Tertiary; Purines; Roscovitine; Stereoisomerism; Substrate Specificity; Threonine; Tyrosine | 2006 |
Effects of substrate analogues and pH on manganese superoxide dismutases.
Topics: Azides; Binding Sites; Electron Spin Resonance Spectroscopy; Escherichia coli; Fluorides; Glycine; Hydrogen-Ion Concentration; Iron; Manganese; Models, Molecular; Mutation; Porphyromonas gingivalis; Protein Conformation; Rhodobacter capsulatus; Structure-Activity Relationship; Superoxide Dismutase; Threonine; Tyrosine | 2006 |
The G972R variant of the insulin receptor substrate-1 gene impairs insulin signaling and cell differentiation in 3T3L1 adipocytes; treatment with a PPARgamma agonist restores normal cell signaling and differentiation.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pioglitazone; PPAR gamma; Serine; Signal Transduction; Thiazolidinediones; Threonine; Transfection; Tyrosine | 2006 |
Reconciling the "old" and "new" views of protein allostery: a molecular simulation study of chemotaxis Y protein (CheY).
Topics: Allosteric Regulation; Bacterial Proteins; Chemotaxis; Computer Simulation; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Models, Molecular; Mutation; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Threonine; Tyrosine | 2006 |
Phosphate group-driven fragmentation of multiply charged phosphopeptide anions. Improved recognition of peptides phosphorylated at serine, threonine, or tyrosine by negative ion electrospray tandem mass spectrometry.
Topics: Amino Acid Sequence; Anions; Phosphates; Phosphopeptides; Phosphorylation; Serine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine; Tyrosine | 2006 |
Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.
Topics: Animals; Cyclin-Dependent Kinases; Cyclins; Meiosis; Mutagenesis, Site-Directed; Mutation; Oocytes; Peptides; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine; Xenopus; Xenopus Proteins | 2006 |
Analysis of the dynamic Bacillus subtilis Ser/Thr/Tyr phosphoproteome implicated in a wide variety of cellular processes.
Topics: Bacillus subtilis; Bacterial Proteins; Cold Temperature; Culture Media; Electrophoresis, Gel, Two-Dimensional; Hot Temperature; Mass Spectrometry; Osmotic Pressure; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Proteomics; Serine; Threonine; Tyrosine | 2006 |
[Phosphorylation of proteasomes and alpha-RNP from rat liver cells].
Topics: Animals; Cell Nucleus; Cytoplasm; Hepatocytes; Male; Molecular Weight; Phosphorylation; Proteasome Endopeptidase Complex; Rats; Ribonucleoproteins; Threonine; Tyrosine | 2005 |
[Subunits of human holoenzyme of DNA dependent RNA polymerase III phosphorylated in vivo].
Topics: Carcinoma, Squamous Cell; Catalytic Domain; Cell Line, Tumor; Cell Nucleus; Chromatography, DEAE-Cellulose; Holoenzymes; Humans; Immunoblotting; Molecular Weight; Phosphorylation; Placenta; RNA Polymerase III; Serine; Threonine; Tyrosine | 2005 |
Effect of Agkistroden blomhoffi (mamushi) on superoxide generation in human neutrophils.
Topics: Agkistrodon; Animals; Cytochromes c; Electrophoresis, Polyacrylamide Gel; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Transport; rac GTP-Binding Proteins; Serine; Superoxides; Threonine; Tyrosine | 2006 |
[Specificity of changes in proteasome properties in diethylmaleate-induced apoptosis of K562 cells].
Topics: Apoptosis; Humans; K562 Cells; Maleates; Molecular Weight; Phosphorylation; Proteasome Endopeptidase Complex; Ribonucleases; Threonine; Tyrosine | 2006 |
Androgen induction of prostate cancer cell invasion is mediated by ezrin.
Topics: Amino Acid Substitution; Androgens; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Collagen; Cytoskeletal Proteins; Drug Combinations; Humans; Laminin; Male; Neoplasm Invasiveness; Phosphorylation; Prostatic Neoplasms; Proteoglycans; Threonine; Tyrosine | 2006 |
Interaction of vanadyl (VO2+) with ligands containing serine, tyrosine, and threonine.
Topics: Crystallography, X-Ray; Ligands; Models, Molecular; Molecular Conformation; Organometallic Compounds; Schiff Bases; Serine; Threonine; Tyrosine; Vanadates | 2006 |
Functional importance of the interhelical hydrogen bond between Thr204 and Tyr174 of sensory rhodopsin II and its alteration during the signaling process.
Topics: Cell Membrane; Halobacterium salinarum; Halorhodopsins; Hydrogen Bonding; Mutagenesis, Site-Directed; Plasmids; Sensory Rhodopsins; Signal Transduction; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2006 |
Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Dual-Specificity Phosphatases; Helix-Loop-Helix Motifs; Humans; Male; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Phosphoprotein Phosphatases; Protein Tyrosine Phosphatases; Sequence Alignment; Substrate Specificity; Testis; Threonine; Tyrosine | 2007 |
Ecto- and exo-protein kinases in Schistosoma mansoni: regulation of surface phosphorylation by acetylcholine and identification of the alpha subunit of CKII as a major secreted protein kinase.
Topics: Acetylcholine; Animals; Biomphalaria; Casein Kinase II; Caseins; Electrophoresis, Polyacrylamide Gel; Heparin; Mice; Phosphorylation; Phosvitin; Protein Kinase Inhibitors; Protein Kinases; Schistosoma mansoni; Serine; Threonine; Tyrosine | 2005 |
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Binding Sites; Chromatography, Liquid; DNA-Binding Proteins; Genes, Bacterial; Mass Spectrometry; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Repressor Proteins; Serine; Threonine; Tyrosine | 2007 |
The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.
Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Dizocilpine Maleate; Endothelial Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Proteins; Occludin; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Threonine; Tyrosine | 2007 |
Activation loop phosphorylation-independent kinase activity of human protein kinase C zeta.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Catalytic Domain; Cell Line; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Humans; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Recombinant Proteins; Sequence Homology, Amino Acid; Spodoptera; Structure-Activity Relationship; Threonine; Tyrosine | 2007 |
LRRK2 exon 41 mutations in sporadic Parkinson disease in Europeans.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Europe; Exons; Female; Histidine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Threonine; Tyrosine | 2007 |
Myocilin mutations among primary open angle glaucoma patients of Kanyakumari district, South India.
Topics: Aged; Asian People; Base Sequence; Cytoskeletal Proteins; Eye Proteins; Female; Glaucoma, Open-Angle; Glycoproteins; Humans; India; Leucine; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Proline; Serine; Threonine; Tyrosine | 2007 |
Electronic structure of the PYP chromophore in its native protein environment.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Glutamic Acid; Models, Molecular; Phenylalanine; Photoreceptors, Microbial; Threonine; Tyrosine; Valine | 2007 |
Identification of histidine phosphorylations in proteins using mass spectrometry and affinity-based techniques.
Topics: Bacterial Proteins; Biochemistry; Histidine; Histidine Kinase; Mass Spectrometry; Models, Chemical; Phosphorylation; Protein Kinases; Serine; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 2007 |
Autophosphorylation properties of inactive and active JNK2.
Topics: Animals; Cell Line; Enzyme Activation; Humans; Isoenzymes; MAP Kinase Signaling System; Mass Spectrometry; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Phosphopeptides; Phosphorylation; Protein Conformation; Threonine; Tyrosine | 2007 |
Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice.
Topics: Animals; Brain; Frontal Lobe; Hippocampus; Hypoxia, Brain; Immunologic Techniques; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred BALB C; Neurogranin; Neurons; Phosphorylation; Staining and Labeling; Threonine; Tissue Distribution; Tyrosine | 2007 |
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
Topics: Adult; Age of Onset; Aged; Asian People; Black or African American; Breast Neoplasms; Case-Control Studies; Checkpoint Kinase 2; DNA Mutational Analysis; DNA, Complementary; Female; Gene Frequency; Genetic Predisposition to Disease; Germ-Line Mutation; Hawaii; Hispanic or Latino; Histidine; Humans; Isoleucine; Leucine; Male; Middle Aged; Mutation; Mutation, Missense; Predictive Value of Tests; Proline; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Risk Assessment; Risk Factors; Threonine; Tyrosine; United States; White People | 2007 |
Dynamics of protein phosphorylation on Ser/Thr/Tyr in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Electrophoresis, Gel, Two-Dimensional; Isoelectric Focusing; Phosphorus Radioisotopes; Phosphorylation; Proteins; Serine; Staining and Labeling; Threonine; Tyrosine | 2007 |
[Reprogramming of nuclear proteasomes in K562 cells undergoing apoptosis. II. Effect of anticancer drug doxorubicin].
Topics: Apoptosis; Cell Nucleus; Doxorubicin; Humans; K562 Cells; Nuclear Proteins; Phosphorylation; Proteasome Endopeptidase Complex; Threonine; Tyrosine | 2007 |
Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Bacillus subtilis; Bacterial Proteins; Conserved Sequence; Escherichia coli; Evolution, Molecular; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteome; Serine; Threonine; Tyrosine | 2008 |
The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state.
Topics: Bacterial Proteins; Crystallography, X-Ray; Databases, Protein; Dimerization; Ions; Lanthanum; Models, Molecular; Models, Statistical; Mycobacterium tuberculosis; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Threonine; Tyrosine | 2007 |
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Down Syndrome; Dyrk Kinases; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; PC12 Cells; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Threonine; Tyrosine | 2008 |
Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach.
Topics: Amino Acid Sequence; Amino Acids; Biophysics; Circular Dichroism; Combinatorial Chemistry Techniques; Dimerization; Glycine; Guanidine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Peptide Library; Peptides; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Structure-Activity Relationship; Temperature; Thermodynamics; Threonine; Tumor Suppressor Protein p53; Tyrosine | 2008 |
Vibrational signatures of protonated, phosphorylated amino acids in the gas phase.
Topics: Gases; Models, Chemical; Molecular Structure; Phosphorylation; Protons; Serine; Spectrophotometry, Infrared; Threonine; Tyrosine; Vibration | 2008 |
Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters.
Topics: Acetylglucosamine; Animals; Enzyme Activation; Epinephrine; Hepatocytes; Isoenzymes; Male; Mass Spectrometry; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Wistar; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2008 |
Inhibitory effects of ginsenosides from the root of Panax ginseng on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation, and translocation of cytosolic compounds to plasma membrane in human neutrophils.
Topics: Cell Membrane; Cytochromes c; Cytosol; Ginsenosides; Neutrophils; Oxidation-Reduction; Panax; Phosphorylation; Plant Roots; Serine; Superoxides; Threonine; Tyrosine | 2008 |
Charge environments around phosphorylation sites in proteins.
Topics: Binding Sites; Databases, Protein; Models, Molecular; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proteins; Serine; Threonine; Tyrosine | 2008 |
Preparation and application of polyclonal and monoclonal sequence-specific anti-phosphoamino acid antibodies.
Topics: Adjuvants, Immunologic; Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Antigens; Chromatography, Affinity; Cross-Linking Reagents; Culture Media, Conditioned; Humans; Mice; Molecular Sequence Data; Peptides; Phosphoamino Acids; Serine; Threonine; Tyrosine | 2004 |
Preparation and analysis of phosphorylated proteins.
Topics: Animals; Binding Sites; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Ligands; Mice; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Serine; T-Lymphocytes; Threonine; Time Factors; Tyrosine | 2001 |
Regulatory phosphorylation of cyclin-dependent kinase 2: insights from molecular dynamics simulations.
Topics: Binding Sites; Catalytic Domain; Cyclin-Dependent Kinase 2; Humans; Phosphorylation; Protein Structure, Secondary; Threonine; Tyrosine | 2008 |
Analysis of dual phosphorylation of Hog1 MAP kinase in Saccharomyces cerevisiae using quantitative mass spectrometry.
Topics: Amino Acid Sequence; Mitogen-Activated Protein Kinases; Osmotic Pressure; Phosphorylation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Threonine; Tyrosine | 2008 |
Differential regulation of threonine and tyrosine phosphorylations on protein kinase Cdelta by G-protein-mediated pathways in platelets.
Topics: Animals; Blood Platelets; Blotting, Western; Chlorocebus aethiops; COS Cells; Diglycerides; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Humans; Mice; Mice, Knockout; Phosphorylation; Protein Kinase C-delta; Signal Transduction; Threonine; Tyrosine | 2009 |
The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins.
Topics: Amino Acid Sequence; Bacterial Proteins; Glycolysis; Lactococcus lactis; Phosphopeptides; Phosphorylation; Proteome; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2008 |
Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Geobacillus stearothermophilus; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Tyrosine | 2008 |
Activation of atypical protein kinase Czeta toward TC10 is regulated by high-fat diet and aerobic exercise in skeletal muscle.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Membrane; Cytoskeletal Proteins; Dietary Fats; Enzyme Activation; Insulin; Isoenzymes; Male; Membrane Proteins; Muscle, Skeletal; Osmolar Concentration; Phosphorylation; Physical Conditioning, Animal; Protein Kinase C; Proto-Oncogene Proteins c-cbl; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction; Threonine; Tyrosine | 2008 |
Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters.
Topics: Amino Acid Sequence; Amino Acids; Cross-Linking Reagents; Esters; Laminin; Lysine; Molecular Sequence Data; Peptides; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinimides; Threonine; Tyrosine | 2008 |
Characteristic negative ion fragmentations of deprotonated peptides containing post-translational modifications: mono-phosphorylated Ser, Thr and Tyr. A joint experimental and theoretical study.
Topics: Amino Acid Sequence; Molecular Sequence Data; Peptides; Phosphorylation; Protein Processing, Post-Translational; Protons; Serine; Spectrometry, Mass, Electrospray Ionization; Threonine; Tyrosine | 2008 |
Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms.
Topics: Amino Acids; Crystallography, X-Ray; Cysteine; Hydrogen; Hydrogen Bonding; Hydroxyl Radical; Protein Conformation; Protein Structure, Secondary; Serine; Sulfhydryl Compounds; Threonine; Tyrosine | 2008 |
Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.
Topics: Binding Sites; Casein Kinase I; Dipeptides; Escherichia coli; Glucose; Glycogen Synthase Kinase 3; Mass Spectrometry; Phosphorylation; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine; Ubiquitin-Protein Ligases | 2008 |
Free tyrosine and tyrosine-rich peptide-dependent superoxide generation catalyzed by a copper-binding, threonine-rich neurotoxic peptide derived from prion protein.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catalysis; Copper; Humans; Models, Chemical; Molecular Structure; Peptides; Prions; Protein Binding; Superoxides; Threonine; Tyrosine | 2009 |
p38alpha is active in vitro and in vivo when monophosphorylated at threonine 180.
Topics: Enzyme Activation; Humans; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Threonine; Tyrosine | 2009 |
Structural characterization of a human Fc fragment engineered for extended serum half-life.
Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Glutamic Acid; Half-Life; Histocompatibility Antigens Class I; Humans; Immunoglobulin Fc Fragments; Immunoglobulin G; Models, Molecular; Protein Conformation; Protein Engineering; Protein Stability; Rats; Receptors, Fc; Threonine; Tyrosine | 2009 |
Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.
Topics: Amino Acids; Archaea; Biological Evolution; Genome, Bacterial; Halobacterium salinarum; Phosphorylation; Proteomics; Serine; Signal Transduction; Threonine; Tyrosine | 2009 |
T cell receptor-mediated activation of p38{alpha} by mono-phosphorylation of the activation loop results in altered substrate specificity.
Topics: Adenosine Triphosphate; Animals; Enzyme Activation; Humans; Kinetics; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Antigen, T-Cell; Recombinant Proteins; Signal Transduction; Substrate Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2009 |
p97/valosin-containing protein (VCP) is highly modulated by phosphorylation and acetylation.
Topics: Acetylation; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Blotting, Western; Cell Cycle Proteins; Cell Line; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Humans; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Mutation; Phosphorylation; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Spodoptera; Threonine; Tyrosine; Valosin Containing Protein | 2009 |
Weak functional constraints on phosphoproteomes.
Topics: Animals; Binding Sites; Evolution, Molecular; Humans; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proteome; Serine; Threonine; Tyrosine | 2009 |
Altered subcellular distribution of c-Abl in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Analysis of Variance; Case-Control Studies; Female; Hippocampus; Humans; Immunoprecipitation; Male; Microscopy, Confocal; Middle Aged; Neurofilament Proteins; Phosphorylation; Proto-Oncogene Proteins c-abl; Subcellular Fractions; tau Proteins; Threonine; Tyrosine | 2009 |
Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species.
Topics: Amino Acids; Bacterial Proteins; Chromatography, Liquid; Cyclic GMP; Mass Spectrometry; Phosphoamino Acids; Phosphopeptides; Phosphorylation; Protein Kinases; Proteome; Pseudomonas aeruginosa; Pseudomonas putida; Serine; Signal Transduction; Threonine; Tyrosine | 2009 |
Negative ion fragmentations of deprotonated peptides containing post-translational modifications: diphosphorylated systems containing Ser, Thr and Tyr. A characteristic phosphate/phosphate cyclisation. A joint experimental and theoretical study.
Topics: Cyclization; Ions; Peptides; Phosphates; Phosphorylation; Protein Processing, Post-Translational; Serine; Spectrum Analysis; Tandem Mass Spectrometry; Threonine; Tyrosine | 2009 |
Occludin phosphorylation in regulation of epithelial tight junctions.
Topics: Animals; Binding Sites; Epithelium; Humans; Membrane Proteins; Mice; Mice, Knockout; Occludin; Phosphorylation; Serine; Threonine; Tight Junctions; Tyrosine | 2009 |
Phosphorylation and consequent stimulation of the tyrosine kinase c-Abl by PKA in mouse spermatozoa; its implications during capacitation.
Topics: Animals; Benzamides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Flagella; Imatinib Mesylate; Male; Mice; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-abl; Pyrimidines; Sperm Capacitation; Spermatozoa; Threonine; Tyrosine | 2009 |
On the road to understanding of the osteoblast adhesion: cytoskeleton organization is rearranged by distinct signaling pathways.
Topics: Animals; Cell Adhesion; Cell Cycle; Cell Line; Cytoskeleton; Intracellular Signaling Peptides and Proteins; Mice; Models, Biological; Osteoblasts; Protein Serine-Threonine Kinases; Signal Transduction; Threonine; Tyrosine | 2009 |
Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit.
Topics: Animals; Anorexia; Body Weight; Bone Morphogenetic Protein Receptors, Type I; Brain Stem; Butadienes; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Enzyme Inhibitors; Feeding Behavior; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Injections, Intraventricular; Keto Acids; Leucine; Male; Melanocortins; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Nitriles; Oxytocin; Pro-Opiomelanocortin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Signal Transduction; Threonine; Time Factors; Tyrosine; Vasotocin | 2009 |
Novel T719P AbetaPP mutation unbalances the relative proportion of amyloid-beta peptides.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mutation; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine | 2009 |
Synthesis of diazo functionalized solid supports and their application towards the enrichment of phosphorylated peptides.
Topics: Caseins; Diazonium Compounds; Filtration; Peptides; Phosphorylation; Threonine; Tyrosine | 2009 |
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Topics: Actins; Amino Acid Sequence; Binding Sites; Biological Transport; Cytokines; Endocytosis; Extracellular Signal-Regulated MAP Kinases; Humans; Jurkat Cells; Microtubules; Models, Biological; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Binding; Protein Interaction Mapping; Proteomics; Receptors, Antigen, T-Cell; RNA Splicing; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2009 |
Phosphorylated proteins of the mammalian mitochondrial ribosome: implications in protein synthesis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cattle; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Escherichia coli Proteins; Immunoblotting; Mammals; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Structure, Tertiary; Proteomics; Ribosomal Proteins; Sequence Alignment; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2009 |
Tyrosine and serine phosphorylation regulate the conformation and subsequent threonine phosphorylation of the L1 cytoplasmic domain.
Topics: Amino Acid Sequence; Antibodies, Phospho-Specific; Casein Kinase II; Cytoplasm; Epitopes; Humans; Molecular Sequence Data; Mutation; Neural Cell Adhesion Molecule L1; Phosphorylation; Protein Folding; Protein Kinase C-alpha; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Threonine; Tyrosine | 2009 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
Cell biology. Evolving cell signals.
Topics: Animals; Binding Sites; Biological Evolution; CDC2 Protein Kinase; Evolution, Molecular; Fungi; Phosphorylation; Protein Binding; Protein Folding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proteins; Serine; Signal Transduction; Threonine; Tyrosine | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Synthesis of Lipoamino acids and their activity against cerebral ischemic injury.
Topics: Anaerobiosis; Animals; Brain; Brain Ischemia; Hydrogen Peroxide; Neuroprotective Agents; Rats; Serine; Threonine; Tyrosine | 2009 |
Effects of sulfur amino acids on tyrosyl or serine/threonine phosphorylation and translocation of cytosolic compounds to cell membrane in stimulus-treated human neutrophils.
Topics: Amino Acids, Sulfur; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Humans; Lipid Peroxidation; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; rac GTP-Binding Proteins; Respiratory Burst; Serine; Superoxides; Threonine; Tyrosine | 2009 |
FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex.
Topics: Actins; Animals; Animals, Newborn; Apoptosis; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen Type I; Enzyme Activation; Fibroblasts; Focal Adhesion Kinase 1; Intracellular Signaling Peptides and Proteins; Leucine; Matrix Metalloproteinase 2; Mechanotransduction, Cellular; Myocardium; Oligopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; RNA Interference; Serine; Sirolimus; Stress, Mechanical; Threonine; Time Factors; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Tyrosine | 2010 |
Analysis of conserved residues in the betapat-3 cytoplasmic tail reveals important functions of integrin in multiple tissues.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Caenorhabditis elegans; Cytoplasm; Female; Humans; Integrin beta1; Integrins; Molecular Sequence Data; Ovulation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Threonine; Tyrosine | 2010 |
The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling.
Topics: Catalytic Domain; Cell Line; Humans; Insulin; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Proline; Protein Subunits; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Threonine; Tyrosine | 2010 |
Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts.
Topics: Animals; Chromatography, Affinity; Cloning, Molecular; Enzyme Activation; Escherichia coli; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Phosphorylation; Protein Isoforms; Rats; Recombinant Fusion Proteins; Signal Transduction; Substrate Specificity; Threonine; Tyrosine | 2011 |
Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.
Topics: Alanine; Binding Sites; Catalysis; Catalytic Domain; Glutamine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Models, Molecular; Polyubiquitin; Protein Conformation; Protein Processing, Post-Translational; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Threonine; Tyrosine; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2010 |
Evolution of protein phosphorylation for distinct functional modules in vertebrate genomes.
Topics: Animals; Conserved Sequence; Evolution, Molecular; Gene Regulatory Networks; Genome; Humans; Phosphoproteins; Phosphorylation; Proteomics; Serine; Structure-Activity Relationship; Threonine; Tyrosine; Vertebrates | 2011 |
Tyrosine dephosphorylation is required for Bak activation in apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Line; Extracellular Signal-Regulated MAP Kinases; Humans; Mitochondria; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatases, Non-Receptor; Serine; Threonine; Tyrosine | 2010 |
Phospho.ELM: a database of phosphorylation sites--update 2011.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Databases, Protein; Humans; Mice; Phosphoproteins; Phosphorylation; Protein Conformation; Sequence Analysis, Protein; Serine; Threonine; Tyrosine | 2011 |
Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase and the role of the modification in catalysis.
Topics: Amino Acid Sequence; Animals; Catalysis; eIF-2 Kinase; Escherichia coli; Humans; Mice; Phosphorylation; Recombinant Proteins; Threonine; Tyrosine | 2011 |
Rampant purifying selection conserves positions with posttranslational modifications in human proteins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Evolution, Molecular; Humans; Models, Genetic; Phylogeny; Protein Processing, Post-Translational; Proteins; Selection, Genetic; Sequence Alignment; Serine; Threonine; Tyrosine | 2011 |
Tyrosine 656 in topoisomerase IIβ is important for the catalytic activity of the enzyme: Identification based on artifactual +80-Da modification at this site.
Topics: Antibodies, Phospho-Specific; Artifacts; Biocatalysis; Blotting, Western; Circular Dichroism; Cyanogen Bromide; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Halogenation; HL-60 Cells; Humans; Isoenzymes; Models, Molecular; Mutation; Phosphorylation; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Threonine; Trypsin; Tyrosine | 2011 |
Characterization of AMPylation on threonine, serine, and tyrosine using mass spectrometry.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Biochemical Phenomena; Mass Spectrometry; Peptides; Serine; Threonine; Tyrosine | 2011 |
A critical step for JNK activation: isomerization by the prolyl isomerase Pin1.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Humans; Jurkat Cells; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 8; NIMA-Interacting Peptidylprolyl Isomerase; Oxidative Stress; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Binding; Protein Conformation; Proteolysis; Subtilisin; Threonine; Tyrosine | 2012 |
Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Chromatography, Liquid; Glycosylation; Humans; Molecular Sequence Data; Proteomics; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2011 |
Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Female; Humans; Lapatinib; Phosphorylation; Quinazolines; Receptor, ErbB-2; Signal Transduction; Threonine; Trastuzumab; Tyrosine | 2012 |
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays | 2011 |
Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation.
Topics: Amino Acid Sequence; Animals; Bone Marrow Cells; Cell Differentiation; Cell Separation; Cytoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunoblotting; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Phosphorylation; Plasma Cells; Receptors, Antigen, B-Cell; Serine; Signal Transduction; Threonine; Tyrosine | 2011 |
Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo.
Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Differentiation; Cell Movement; Cell Proliferation; Class Ia Phosphatidylinositol 3-Kinase; Curcuma; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Furans; Green Fluorescent Proteins; Heterocyclic Compounds, 2-Ring; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Medicine, Chinese Traditional; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Physiologic; Phosphorylation; Plants, Medicinal; Proto-Oncogene Protein c-fli-1; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Threonine; Tyrosine; Vascular Endothelial Growth Factor A; Wound Healing; Zebrafish | 2012 |
A novel sequence-based method for phosphorylation site prediction with feature selection and analysis.
Topics: Binding Sites; Computational Biology; Data Mining; Databases, Protein; Peptides; Phosphoproteins; Phosphorylation; Predictive Value of Tests; Protein Processing, Post-Translational; Sequence Analysis, Protein; Serine; Support Vector Machine; Threonine; Tyrosine | 2012 |
Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence.
Topics: Amino Acid Sequence; Bacterial Proteins; Listeria monocytogenes; Molecular Sequence Data; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteomics; Serine; Threonine; Tyrosine; Virulence | 2011 |
Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2.
Topics: Acetyl-CoA Carboxylase; Aldehydes; AMP-Activated Protein Kinases; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Berberine; Blood Glucose; Cholesterol; Enzyme Activation; Humans; Intercellular Adhesion Molecule-1; Ion Channels; Mice; Mitochondrial Proteins; Phosphorylation; Plaque, Atherosclerotic; Protein Transport; Serine; Threonine; Transcription, Genetic; Triglycerides; Tyrosine; Uncoupling Protein 2; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2011 |
Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation.
Topics: Amino Acid Motifs; Bacterial Proteins; Computational Biology; Fractional Precipitation; Phosphoproteins; Phosphorylation; Phylogeny; Protein Kinases; Regulatory Elements, Transcriptional; Serine; Software; Spores, Bacterial; Streptomyces coelicolor; Threonine; Tyrosine | 2011 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Model studies on iTRAQ modification of peptides: sequence-dependent reaction specificity.
Topics: Acylation; Amino Acid Sequence; Escherichia coli Proteins; Hydroxylamine; Oligopeptides; Peptide Fragments; Peptide Mapping; Reference Standards; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staining and Labeling; Tandem Mass Spectrometry; Threonine; Tyrosine | 2012 |
Reversible Ser/Thr SHIP phosphorylation: a new paradigm in phosphoinositide signalling?: Targeting of SHIP1/2 phosphatases may be controlled by phosphorylation on Ser and Thr residues.
Topics: Animals; Cell Differentiation; Cell Membrane; Cell Nucleus; Enzyme Activation; Humans; Inositol Polyphosphate 5-Phosphatases; Mice; Mice, Knockout; Phosphatidylinositol Phosphates; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Interaction Mapping; PTEN Phosphohydrolase; Serine; Signal Transduction; Substrate Specificity; Threonine; Tyrosine | 2012 |
Diminished muscle growth in the obese Zucker rat following overload is associated with hyperphosphorylation of AMPK and dsRNA-dependent protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; eIF-2 Kinase; Extracellular Signal-Regulated MAP Kinases; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Phosphorylation; Rats; Rats, Zucker; Serine; Signal Transduction; Threonine; Tyrosine; Ubiquitination | 2012 |
Cell signaling, post-translational protein modifications and NMR spectroscopy.
Topics: Acetylation; Acylation; Alkylation; Amino Acids; Arginine; Cell Communication; Eukaryotic Cells; Glycosylation; Histidine; Lysine; Magnetic Resonance Spectroscopy; Methylation; Phosphorylation; Protein Processing, Post-Translational; Proteins; Serine; Threonine; Tyrosine | 2012 |
CDPKs are dual-specificity protein kinases and tyrosine autophosphorylation attenuates kinase activity.
Topics: Arabidopsis Proteins; Calcium; Calcium-Binding Proteins; Immunoblotting; Mass Spectrometry; Mutagenesis, Site-Directed; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine | 2012 |
Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote.
Topics: Amino Acid Sequence; Anticodon; Arginine; Base Sequence; Codon; Cytoplasm; Isoenzymes; Molecular Sequence Data; Mutation; RNA Editing; RNA, Transfer; RNA, Transfer, Thr; Saccharomyces cerevisiae; Sequence Alignment; Serine; Threonine; Threonine-tRNA Ligase; Transfer RNA Aminoacylation; Tyrosine | 2013 |
Influence of the O-phosphorylation of serine, threonine and tyrosine in proteins on the amidic ¹⁵N chemical shielding anisotropy tensors.
Topics: Anisotropy; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphates; Phosphorylation; Proteins; Serine; Solvents; Threonine; Tyrosine | 2013 |
Critical role of S1PR1 and integrin β4 in HGF/c-Met-mediated increases in vascular integrity.
Topics: Cell Membrane; Electrophysiology; Endothelial Cells; Hepatocyte Growth Factor; Humans; Integrin beta4; Lung; Membrane Microdomains; Microcirculation; Models, Biological; Proto-Oncogene Proteins c-met; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; RNA, Small Interfering; Sphingosine-1-Phosphate Receptors; Threonine; Transcriptional Activation; Tyrosine | 2013 |
Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.
Topics: Carrier Proteins; Histones; Humans; Kinetics; mRNA Cleavage and Polyadenylation Factors; Mutagenesis, Site-Directed; Mutant Proteins; Nuclear Proteins; Peptide Fragments; Phosphorylation; Point Mutation; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Processing, Post-Translational; Recombinant Proteins; RNA Folding; RNA-Binding Proteins; RNA, Messenger; Serine; Threonine; Tyrosine | 2013 |
Amino acid building blocks for Fmoc solid-phase synthesis of peptides phosphocholinated at serine, threonine, and tyrosine.
Topics: Amino Acids; Fluorenes; Peptides; Phosphorylcholine; Serine; Solid-Phase Synthesis Techniques; Threonine; Tyrosine | 2013 |
Global phosphoproteomic analysis reveals diverse functions of serine/threonine/tyrosine phosphorylation in the model cyanobacterium Synechococcus sp. strain PCC 7002.
Topics: Bacteria; Bacterial Proteins; Gene Ontology; Phosphoproteins; Phosphorylation; Photosynthesis; Proteomics; Serine; Signal Transduction; Synechococcus; Threonine; Tyrosine | 2013 |
HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation.
Topics: Animals; Blotting, Western; Carrier Proteins; Chromatography, Liquid; Cytoplasm; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoprecipitation; Mice; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subcellular Fractions; Substrate Specificity; Tandem Mass Spectrometry; Threonine; Tyrosine | 2013 |
Cryopreservation of common carp (Cyprinus carpio L.) sperm induces protein phosphorylation in tyrosine and threonine residues.
Topics: Animals; Carps; Cryopreservation; Cryoprotective Agents; Male; Phosphorylation; Protein Kinases; Semen Preservation; Sperm Motility; Spermatozoa; Threonine; Tyrosine; Up-Regulation | 2013 |
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2013 |
Mechanism of dual specificity kinase activity of DYRK1A.
Topics: Animals; Biocatalysis; Dyrk Kinases; Escherichia coli; HeLa Cells; Humans; Kinetics; Models, Molecular; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Serine; Substrate Specificity; Thermodynamics; Threonine; Transfection; Tyrosine | 2013 |
Tyrosine-functionalized CuInS2 quantum dots as a fluorescence probe for the determination of biothiols, histidine and threonine.
Topics: Copper; Fluorescent Dyes; Histidine; Humans; Insulin; Quantum Dots; Spectrometry, Fluorescence; Sulfhydryl Compounds; Threonine; Tyrosine | 2013 |
Evolutionary conservation of mammalian sperm proteins associates with overall, not tyrosine, phosphorylation in human spermatozoa.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Conserved Sequence; Electrophoresis, Gel, Two-Dimensional; Evolution, Molecular; Fertility; Gene Expression Regulation; Humans; Male; Molecular Sequence Annotation; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Spermatozoa; Threonine; Tyrosine | 2013 |
Covalent bond formation between amino acids and lignin: cross-coupling between proteins and lignin.
Topics: Amino Acids; Cell Wall; Chromatography, High Pressure Liquid; Cysteine; Horseradish Peroxidase; Hydrogen Peroxide; Indolequinones; Lignin; Nuclear Magnetic Resonance, Biomolecular; Phenols; Proteins; Threonine; Tyrosine | 2013 |
A chiral ligand exchange CE system for monitoring inhibitory effect of kojic acid on tyrosinase.
Topics: Alanine; beta-Cyclodextrins; Dansyl Compounds; Electrophoresis, Capillary; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Ligands; Monophenol Monooxygenase; Pyrones; Recombinant Proteins; Reproducibility of Results; Solutions; Soy Foods; Stereoisomerism; Threonine; Tyrosine; Zinc | 2013 |
Global phosphoproteomic analysis of Daphnia pulex reveals evolutionary conservation of Ser/Thr/Tyr phosphorylation.
Topics: Amino Acid Sequence; Animals; Arthropod Proteins; Biological Evolution; Conserved Sequence; Daphnia; Gene Expression Regulation; Humans; Molecular Sequence Annotation; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Proteomics; Serine; Threonine; Titanium; Tyrosine | 2014 |
Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11.
Topics: Cell Line; Crystallization; Escherichia coli; Fluorescein-5-isothiocyanate; HLA-A11 Antigen; Humans; Immunity, Innate; Killer Cells, Natural; Models, Molecular; Mutagenesis; Protein Conformation; Receptors, KIR; Reverse Transcriptase Polymerase Chain Reaction; Surface Plasmon Resonance; Threonine; Tyrosine; X-Ray Diffraction | 2014 |
The nucleotide-binding oligomerization domain-containing protein 1 (NOD1) polymorphism S7N does not affect receptor function.
Topics: Amino Acid Sequence; Binding Sites; Black or African American; HEK293 Cells; Humans; Immunoblotting; Luciferases; Models, Molecular; Molecular Sequence Data; Mutation; NF-kappa B; Nod1 Signaling Adaptor Protein; Phosphorylation; Polymorphism, Genetic; Protein Structure, Tertiary; Serine; Signal Transduction; Threonine; Tyrosine; White People | 2014 |
Phosphoregulation of the human SMN complex.
Topics: Amino Acid Sequence; Coiled Bodies; HeLa Cells; Humans; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Proteome; Ribonucleoproteins, Small Nuclear; Serine; SMN Complex Proteins; Threonine; Tyrosine | 2014 |
Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.
Topics: Animals; Anisomycin; Antigens, CD; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Thapsigargin; Threonine; TOR Serine-Threonine Kinases; Tunicamycin; Tyrosine | 2014 |
Ser/Thr/Tyr phosphoproteome characterization of Acinetobacter baumannii: comparison between a reference strain and a highly invasive multidrug-resistant clinical isolate.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Chromatography; Drug Resistance, Multiple, Bacterial; Glycolysis; Mass Spectrometry; Molecular Sequence Data; Peptides; Phenotype; Phosphorylation; Proteome; Proteomics; Serine; Tandem Mass Spectrometry; Threonine; Titanium; Tyrosine | 2014 |
Novel derivatives of monascus pigment having a high CETP inhibitory activity.
Topics: Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Kinetics; Lipoproteins, HDL; Molecular Structure; Monascus; Pigments, Biological; Threonine; Tyrosine | 2014 |
Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling.
Topics: Algorithms; HeLa Cells; Humans; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Proteome; Sequence Analysis, Protein; Serine; Signal Transduction; Threonine; Tyrosine | 2014 |
Quantitative proteome analyses identify PrfA-responsive proteins and phosphoproteins in Listeria monocytogenes.
Topics: Bacterial Proteins; Binding Sites; Chromatography, Liquid; Culture Media; Glucose; Listeria monocytogenes; Mutation; Peptide Termination Factors; Peptides; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Purines; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine; Virulence | 2014 |
Using support vector machines to identify protein phosphorylation sites in viruses.
Topics: Amino Acid Sequence; Databases, Protein; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Serine; Support Vector Machine; Threonine; Tyrosine; Viral Proteins | 2015 |
Investigation of the dominant positive effect of porcine farnesoid X receptor (FXR) splice variant 1.
Topics: Animals; Genes, Dominant; Glycine; Hep G2 Cells; Humans; Methionine; Mutagenesis, Insertional; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Sus scrofa; Threonine; Transfection; Tyrosine | 2015 |
Activation of AtMPK9 through autophosphorylation that makes it independent of the canonical MAPK cascades.
Topics: Amino Acid Motifs; Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Biocatalysis; Cells, Cultured; Enzyme Activation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Models, Molecular; Mutant Proteins; Oligopeptides; Phosphorylation; Plant Roots; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Threonine; Tyrosine | 2015 |
Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity.
Topics: Animals; Cardiomegaly; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Ligands; Mutation; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Rats; Receptors, Adrenergic, beta; Serine; Signal Transduction; src Homology Domains; Threonine; Tyrosine | 2015 |
Phosphorylation site prediction in plants.
Topics: Binding Sites; Computational Biology; Databases, Protein; Internet; Machine Learning; Models, Statistical; Phosphorylation; Plant Proteins; Plants; Serine; Software; Threonine; Tyrosine | 2015 |
[Identifying phosphopeptide by searching a site annotated protein database].
Topics: Databases, Protein; Phosphopeptides; Phosphorylation; Proteomics; Reproducibility of Results; Serine; Threonine; Tyrosine | 2015 |
Useful agents against aflatoxin B1 - antibacterial azomethine and Mn(III) complexes involving L-Threonine, L-Serine, and L-Tyrosine.
Topics: Aflatoxin B1; Anti-Bacterial Agents; Antidotes; Azo Compounds; Bacteria; Female; Humans; Male; Manganese; Serine; Thiosemicarbazones; Threonine; Tyrosine | 2016 |
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Renal Cell; Catenins; Cell Transformation, Neoplastic; Delta Catenin; Female; Humans; Immunoenzyme Techniques; Immunoprecipitation; Kidney Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Serine; Threonine; Tissue Array Analysis; Tumor Cells, Cultured; Tyrosine | 2015 |
Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules.
Topics: Amino Acid Sequence; Cell Line; Gene Expression Regulation; Humans; Interleukin-2; Interleukin-2 Receptor beta Subunit; Janus Kinase 3; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Serine; Signal Transduction; STAT5 Transcription Factor; Threonine; Tyrosine | 2015 |
Detection and Differentiation of Threonine- and Tyrosine-Monophosphorylated Forms of ERK1/2 by Capillary Isoelectric Focusing-Immunoassay.
Topics: Bradykinin; Cell Line; Humans; Immunoassay; Isoelectric Focusing; Leukocytes, Mononuclear; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Phosphorylation; Threonine; Tyrosine | 2015 |
The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
Topics: Bone Density Conservation Agents; Catalysis; Catalytic Domain; Crystallization; Diphosphonates; Drug Evaluation, Preclinical; Geranyltranstransferase; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Imidazoles; Inhibitory Concentration 50; Molecular Conformation; Mutation; Nitrogen; Oligonucleotides; Protein Binding; Recombinant Proteins; Threonine; Tyrosine; Zoledronic Acid | 2015 |
Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation.
Topics: Antigens, CD; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation; Hep G2 Cells; Humans; Insulin; Lipopolysaccharides; Phosphorylation; Poly I-C; Protein Biosynthesis; Receptor, Insulin; RNA, Double-Stranded; Signal Transduction; Threonine; Tyrosine; Tyrphostins | 2015 |
Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Catalytic Domain; Cloning, Molecular; DNA, Viral; Escherichia coli; Gene Expression; HIV Reverse Transcriptase; HIV-1; Kinetics; Models, Molecular; Mutation; Phenylalanine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA, Viral; Structure-Activity Relationship; Threonine; Tyrosine; Zidovudine | 2015 |
Site-Specific Ser/Thr/Tyr Phosphoproteome of Sinorhizobium meliloti at Stationary Phase.
Topics: Bacterial Proteins; Computational Biology; Phosphoproteins; Phosphorylation; Proteome; Sequence Analysis, Protein; Serine; Sinorhizobium meliloti; Subcellular Fractions; Tandem Mass Spectrometry; Threonine; Tyrosine | 2015 |
Arabidopsis Yak1 protein (AtYak1) is a dual specificity protein kinase.
Topics: Annexins; Arabidopsis; Arabidopsis Proteins; Electrophoresis, Gel, Two-Dimensional; Mutation; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Tyrosine | 2015 |
Stereoselective recognition of the Ac-Glu-Tyr-OH dipeptide by pseudopeptidic cages.
Topics: Amides; Cyclohexanes; Dipeptides; Glutamine; Models, Biological; Molecular Structure; Serine; Stereoisomerism; Threonine; Tyrosine | 2015 |
The Sensor Histidine Kinases AHK2 and AHK3 Proceed into Multiple Serine/Threonine/Tyrosine Phosphorylation Pathways in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Histidine Kinase; Phosphorylation; Protein Kinases; Serine; Threonine; Tyrosine | 2016 |
Identification of Connexin43 Phosphorylation and S-Nitrosylation in Cultured Primary Vascular Cells.
Topics: Biotin; Blotting, Western; Cells, Cultured; Connexin 43; Cysteine; Fluorescent Antibody Technique; Human Umbilical Vein Endothelial Cells; Humans; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; S-Nitrosothiols; Serine; Threonine; Tyrosine | 2016 |
Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses.
Topics: Capsid; Dependovirus; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Genome, Human; HEK293 Cells; Humans; Lysine; Serine; Serogroup; Threonine; Transduction, Genetic; Tyrosine | 2016 |
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult | 2016 |
Autophosphorylation of Specific Threonine and Tyrosine Residues in Arabidopsis CERK1 is Essential for the Activation of Chitin-Induced Immune Signaling.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Chitin; Mutation; Phosphorylation; Plant Immunity; Plants, Genetically Modified; Protein Domains; Protein Serine-Threonine Kinases; Signal Transduction; Threonine; Tyrosine | 2016 |
Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes.
Topics: Animals; Calcineurin; Cells, Cultured; Mice; Microfilament Proteins; Phosphorylation; Podocytes; Receptor Cross-Talk; rhoA GTP-Binding Protein; Serine; Signal Transduction; Threonine; Tyrosine | 2017 |
Podocyte biology: Dynamic control of actin remodelling.
Topics: Actins; Phosphorylation; Podocytes; Serine; Threonine; Tyrosine | 2016 |
The CYP79A1 catalyzed conversion of tyrosine to (E)-p-hydroxyphenylacetaldoxime unravelled using an improved method for homology modeling.
Topics: Arginine; Cytochrome P-450 Enzyme System; Models, Biological; Oximes; Sorghum; Threonine; Tyrosine | 2017 |
Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p.
Topics: Phosphorylation; Protein Binding; Protein Kinases; Protein Structure, Tertiary; Proteolysis; RNA Polymerase II; Saccharomyces cerevisiae Proteins; Serine; Threonine; Transcription Factors; Transcription, Genetic; Tyrosine | 2017 |
Characterization and application studies of ProxyPhos, a chemosensor for the detection of proximally phosphorylated peptides and proteins in aqueous solutions.
Topics: Fluorescent Dyes; Peptides; Phosphorylation; Proteins; Serine; Spectrometry, Fluorescence; Threonine; Tyrosine | 2017 |
iMulti-HumPhos: a multi-label classifier for identifying human phosphorylated proteins using multiple kernel learning based support vector machines.
Topics: Benchmarking; Computational Biology; Datasets as Topic; Humans; Internet; Phosphorylation; Protein Processing, Post-Translational; Proteins; Serine; Software; Support Vector Machine; Threonine; Tyrosine | 2017 |
FPD: A comprehensive phosphorylation database in fungi.
Topics: Animals; Databases, Factual; Fungal Proteins; Fungi; Humans; Phosphorylation; Plants; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2017 |
Prediction of phosphorylation sites based on Krawtchouk image moments.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Area Under Curve; Computational Biology; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; ROC Curve; Serine; Support Vector Machine; Threonine; Tyrosine | 2017 |
Protective potential of thymoquinone against peroxynitrite induced modifications in histone H2A: In vitro studies.
Topics: Antioxidants; Arginine; Benzoquinones; Histones; Humans; Lysine; Nigella sativa; Oxidative Stress; Peroxynitrous Acid; Proline; Threonine; Tyrosine | 2018 |
Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells.
Topics: Animals; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Hydrogen Peroxide; Lung; Male; Mice; Mitochondria; Mitogen-Activated Protein Kinase 1; Oxidation-Reduction; Phosphorylation; Subcellular Fractions; Threonine; Tyrosine | 2018 |
Regiospecificity of a novel bacterial lipoxygenase from Myxococcus xanthus for polyunsaturated fatty acids.
Topics: Amino Acid Sequence; Arachidonate 15-Lipoxygenase; Fatty Acids, Unsaturated; Lipoxygenase; Myxococcus xanthus; Sequence Homology, Amino Acid; Substrate Specificity; Threonine; Tyrosine | 2018 |
Phosphorylation of different tau sites during progression of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Female; Humans; Male; Middle Aged; Phosphorylation; Psychiatric Status Rating Scales; Serine; Statistics, Nonparametric; tau Proteins; Threonine; Tyrosine | 2018 |
QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Detergents; Glutamine; Hot Temperature; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Protein Binding; Protein Stability; Protein Structure, Secondary; Receptors, Chemokine; Solubility; Threonine; Tyrosine; Water | 2018 |
AMBER and CHARMM Force Fields Inconsistently Portray the Microscopic Details of Phosphorylation.
Topics: Hydrogen Bonding; Molecular Dynamics Simulation; Phosphorylation; Protein Conformation; Serine; Threonine; Tyrosine | 2019 |
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.
Topics: Cell Division; Crystallography, X-Ray; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Fusion Proteins, bcr-abl; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteolysis; Recombinant Proteins; Signal Transduction; src-Family Kinases; Threonine; Tyrosine | 2019 |
Covalent Labeling with Diethylpyrocarbonate: Sensitive to the Residue Microenvironment, Providing Improved Analysis of Protein Higher Order Structure by Mass Spectrometry.
Topics: beta 2-Microglobulin; Diethyl Pyrocarbonate; Human Growth Hormone; Humans; Mass Spectrometry; Peptide Fragments; Protein Conformation; Serine; Threonine; Tyrosine; Ubiquitin | 2019 |
Quantification of the Dynamic Phosphorylation Process of ERK Using Stable Isotope Dilution Selective Reaction Monitoring Mass Spectrometry.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; HeLa Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Mutation; PC12 Cells; Phosphorylation; Rats; Signal Transduction; Threonine; Tyrosine | 2019 |
Boosting phosphorylation site prediction with sequence feature-based machine learning.
Topics: Algorithms; Animals; Binding Sites; Computational Biology; Databases, Protein; Humans; Machine Learning; Models, Molecular; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sequence Analysis, Protein; Serine; Species Specificity; Threonine; Tyrosine | 2020 |
Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation.
Topics: Cell Cycle Proteins; Fragile X Mental Retardation Protein; Humans; Nuclear Magnetic Resonance, Biomolecular; Phase Transition; Phosphorylation; Polyadenylation; Protein Biosynthesis; RNA, Messenger; Serine; Signal Transduction; Threonine; Tyrosine | 2019 |
Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
Topics: Allosteric Regulation; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Disulfides; Ligands; Metals; Models, Molecular; Mutation; Protein Domains; Protein Engineering; Protein Multimerization; Retinol-Binding Proteins, Cellular; Threonine; Tyrosine; Zinc | 2019 |
Random coil chemical shifts for serine, threonine and tyrosine phosphorylation over a broad pH range.
Topics: Amino Acids; Hydrogen-Ion Concentration; Intrinsically Disordered Proteins; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Structure, Secondary; Serine; Temperature; Threonine; Tyrosine | 2019 |
Antidepressant-Like Effect of β-Lactolin, a Glycine-Threonine-Tryptophan-Tyrosine Peptide.
Topics: Animals; Antidepressive Agents; Benzazepines; Dopamine; Frontal Lobe; Glycine; Hindlimb Suspension; Mice; Oligopeptides; Threonine; Tryptophan; Tyrosine; Whey Proteins | 2019 |
β-lactolin, a whey-derived glycine-threonine-tryptophan-tyrosine lactotetrapeptide, improves prefrontal cortex-associated reversal learning in mice.
Topics: Animals; Attention; Cognition; Executive Function; Glycine; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Prefrontal Cortex; Reversal Learning; Threonine; Tryptophan; Tyrosine; Whey; Whey Proteins | 2020 |
Amino acids profiles of children who stutter compared to their fluent sibling.
Topics: Case-Control Studies; Child; Child, Preschool; Female; Glutamic Acid; Hair; Histidine; Humans; Isoleucine; Male; Siblings; Stuttering; Threonine; Tyrosine | 2020 |
Feature of Heart Rate Variability and Metabolic Mechanism in Female College Students with Depression.
Topics: Adolescent; Autonomic Nervous System; Depression; Fatigue; Female; Glycine; Heart Rate; Humans; Metabolomics; Monitoring, Physiologic; Pyrimidines; Serine; Steroids; Stress, Physiological; Students; Threonine; Tyrosine; Ubiquinone; Urine; Young Adult | 2020 |
Elaboration of Novel TTK1 Inhibitory Leads via QSAR-Guided Selection of Crystallographic Pharmacophores Followed By In Vitro Assay.
Topics: Ligands; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quantitative Structure-Activity Relationship; Threonine; Tyrosine | 2021 |
Improved GROMOS 54A7 Charge Sets for Phosphorylated Tyr, Ser, and Thr to Deal with pH-Dependent Binding Phenomena.
Topics: Binding Sites; Hydrogen-Ion Concentration; Molecular Dynamics Simulation; Phosphorylation; Serine; Threonine; Tyrosine | 2020 |
Intracellular Ser/Thr/Tyr phosphoproteome of the oral commensal Streptococcus gordonii DL1.
Topics: Bacterial Proteins; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Humans; Mouth; Phosphoproteins; Phosphorylation; Serine; Streptococcus gordonii; Tandem Mass Spectrometry; Threonine; Tyrosine | 2020 |
DeepPPSite: A deep learning-based model for analysis and prediction of phosphorylation sites using efficient sequence information.
Topics: Amino Acid Sequence; Animals; Computational Biology; Databases, Protein; Deep Learning; Models, Statistical; Phosphorylation; Protein Processing, Post-Translational; ROC Curve; Sequence Analysis, Protein; Serine; Threonine; Tyrosine | 2021 |
mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1.
Topics: Amino Acid Motifs; Autoantigens; HEK293 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Naphthyridines; Phosphorylation; Protein Binding; Protein Biosynthesis; Ribonucleoproteins; Serine; Sirolimus; SS-B Antigen; Threonine; Tyrosine | 2021 |
Differential Role of Threonine and Tyrosine Phosphorylation in the Activation and Activity of the Yeast MAPK Slt2.
Topics: Antibodies; Enzyme Activation; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Tyrosine | 2021 |
Amino Acid Nutrition for Optimum Growth, Development, Reproduction, and Health of Zoo Animals.
Topics: Amino Acids; Animals; Animals, Zoo; Cystine; Humans; Isoleucine; Leucine; Methionine; Reproduction; Threonine; Tyrosine | 2021 |
Composition of Amino Acids in Foodstuffs for Humans and Animals.
Topics: Amino Acids; Animals; Humans; Isoleucine; Leucine; Methionine; Serine; Swine; Threonine; Tyrosine | 2021 |
Extensive regulation of enzyme activity by phosphorylation in Escherichia coli.
Topics: Binding Sites; Enzymes; Escherichia coli; Escherichia coli Proteins; Mass Spectrometry; Metabolomics; Mutation; Phosphorylation; Protein Processing, Post-Translational; Proteome; Proteomics; Serine; Threonine; Tyrosine | 2021 |
Discerning Tyrosine Phosphorylation from Multiple Phosphorylations Using a Nanofluidic Logic Platform.
Topics: Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Serine; Threonine; Tyrosine | 2021 |
TTK predicts triple positive breast cancer prognosis and regulates tumor proliferation and invasion.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Prognosis; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Threonine; Tyrosine | 2022 |
Epitope Mapping with Diethylpyrocarbonate Covalent Labeling-Mass Spectrometry.
Topics: Diethyl Pyrocarbonate; Epitope Mapping; Mass Spectrometry; Threonine; Tyrosine | 2022 |
Clostridioides difficile Phosphoproteomics Shows an Expansion of Phosphorylated Proteins in Stationary Growth Phase.
Topics: Clostridioides; Clostridioides difficile; Serine; Threonine; Tyrosine | 2022 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Evolutionary genomic relationships and coupling in MK-STYX and STYX pseudophosphatases.
Topics: Dual-Specificity Phosphatases; Mitogen-Activated Protein Kinases; Phylogeny; Threonine; Tyrosine | 2022 |
Metabolomics study of the effect of Danggui Buxue Tang on rats with chronic fatigue syndrome.
Topics: Angelica sinensis; Animals; Drugs, Chinese Herbal; Fatigue Syndrome, Chronic; Glycine; Metabolomics; Rats; Serine; Threonine; Tyrosine | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
New insights into the effect of bisphenol AF exposure on maternal mammary glands at various stages of gestation in mice.
Topics: Amino Acids; Ammonia; Animals; Benzhydryl Compounds; Female; Fluorocarbons; Mice; Ornithine; Phenylalanine; Pregnancy; Proline; RNA, Messenger; Threonine; Tyrosine; Valine | 2022 |
The amino acid profile of Camelina sativa seeds correlates with the strongest immune response in dairy ewes.
Topics: Amino Acids; Animal Feed; Animals; Brassicaceae; Diet; Fatty Acids; Fatty Acids, Unsaturated; Female; Immunity, Innate; Interferon Regulatory Factors; Interferon-beta; Interleukin-10; Interleukin-1beta; Interleukin-8; Lysine; Mitogen-Activated Protein Kinases; Seeds; Serine; Sheep; Threonine; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; Tyrosine | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; T-Lymphocytes; Threonine; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tyrosine | 2022 |
Inhibition of 26S proteasome enhances AKAP3-mediated cAMP-PKA signaling during boar sperm capacitation.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Male; Phosphorylation; Proteasome Endopeptidase Complex; Semen; Serine; Sperm Capacitation; Spermatozoa; Swine; Threonine; Tyrosine; Ubiquitins | 2022 |
Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling.
Topics: Adipocytes; Animals; Diabetes Mellitus, Type 2; Homeostasis; Insulin; Insulin Resistance; Male; Mice; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Threonine; Tyrosine | 2022 |
Metabolomics Profiling of Nephrotic Syndrome towards Biomarker Discovery.
Topics: Arginine; Biomarkers; Humans; Lysine; Metabolome; Metabolomics; Nephrotic Syndrome; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; Glycine; Hypertension; Phenylalanine; Plant Extracts; Rats; Rats, Inbred Dahl; Renal Insufficiency; Serine; Sodium Chloride; Sodium Chloride, Dietary; Threonine; Tyrosine | 2022 |
Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation.
Topics: Animals; Apoptosis; Inflammation; Mice; Phosphorylation; Protein Kinases; Receptor-Interacting Protein Serine-Threonine Kinases; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 2022 |
Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy.
Topics: Animals; Cardiomegaly; Cardiomyopathy, Hypertrophic; Mice; Phosphorylation; Proteome; Serine; Threonine; Tyrosine | 2022 |
Evolutionary divergence in the conformational landscapes of tyrosine vs serine/threonine kinases.
Topics: Molecular Dynamics Simulation; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Serine; Threonine; Tyrosine | 2022 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Synergistic Targeting of DNA-PK and KIT Signaling Pathways in KIT Mutant Acute Myeloid Leukemia.
Topics: Animals; Apoptosis; Cell Line, Tumor; Dasatinib; DNA; DNA-Activated Protein Kinase; Leukemia, Myeloid, Acute; Mice; Mutation; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; Serine; Signal Transduction; Threonine; TOR Serine-Threonine Kinases; Tyrosine | 2023 |
Embryonic poly(A)-binding protein interacts with translation-related proteins and undergoes phosphorylation on the serine, threonine, and tyrosine residues in the mouse oocytes and early embryos.
Topics: Animals; Humans; Mice; Oocytes; Phosphorylation; Poly(A)-Binding Proteins; Serine; Threonine; Tyrosine | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Standardized ileal digestibility of amino acids in cottonseed meal fed to pregnant and non-pregnant sows.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Cottonseed Oil; Cysteine; Diet; Digestion; Female; Glycine max; Ileum; Methionine; Pregnancy; Serine; Swine; Threonine; Tyrosine | 2023 |
Integration of semi-empirical MS/MS library with characteristic features for the annotation of novel amino acid-conjugated bile acids.
Topics: Alanine; Amino Acids; Animals; Bile Acids and Salts; Chromatography, Liquid; Dogs; Glycine; Humans; Leucine; Lysine; Methionine; Mice; Rats; Tandem Mass Spectrometry; Threonine; Tyrosine | 2023 |
Differential tyrosine and serine/threonine phosphorylation/dephosphorylation pathways regulate the expression of α7 versus α3β4 nicotinic receptor subtypes in mouse hippocampal neurons.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Hippocampus; Humans; Mice; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Serine; Threonine; Tyrosine | 2023 |
Detection and identification of amino acids and proteins using their intrinsic fluorescence in the visible light spectrum.
Topics: Alanine; Amino Acids; Arginine; Cystine; Fluorescence; Glycine; Leucine; Methionine; Proteins; Serine; Threonine; Tyrosine; Valine | 2023 |