tyrosine has been researched along with sq-23377 in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.82) | 18.7374 |
| 1990's | 34 (61.82) | 18.2507 |
| 2000's | 17 (30.91) | 29.6817 |
| 2010's | 3 (5.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen-Dayag, A; Pecht, I; Schneider, H | 1 |
| Comoglio, PM; Ferracini, R; Gandino, L; Magni, M; Munaron, L; Naldini, L | 1 |
| Gorczynski, R; Huang, CK; Love, J; Mills, GB; Stanley, JB | 1 |
| Dy, RC; Earp, S; Herman, B; Huckle, WR; Prokop, CA | 1 |
| Brunswick, M; Mond, JJ; Samelson, LE | 1 |
| Conklyn, MJ; Connelly, PA; Farrell, CA; Merenda, JM; Showell, HJ | 1 |
| DeFranco, AL; Fahey, KA; Gold, MR; Matsuuchi, L; Page, DM | 1 |
| Ishida, Y; Kawahara, Y; Koide, M; Shii, K; Tsuda, T; Yokoyama, M | 1 |
| Edgeworth, J; Freemont, P; Hogg, N | 1 |
| Anel, A; Kleinfeld, AM; Richieri, GV | 1 |
| Hagmann, W | 1 |
| Abu-Lawi, KI; Sultzer, BM | 1 |
| Belohradsky, B; Buc, HA; Choquet, D; Fischer, A; Hivroz, C; Le Deist, F; Oleastro, M; Partiseti, M; Thomas, C | 1 |
| Dawson, AP; Gibson, I; Griffiths, SL; Zeytinoğlu, H | 1 |
| Leach, KL; Ruff, VA | 1 |
| Bukowski, R; Edinger, MG; Finke, JH; Hidalgo, OF; Kolenko, V; Kudoh, S; Panuto, J; Rayman, P; Tubbs, RR; Wang, Q | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 1 |
| Farndale, RW; Jenner, S; Sage, SO | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| Alexander, RW; Griendling, KK; Kai, H; Lassègue, B; Ollerenshaw, JD; Runge, MS | 1 |
| Aussel, C; Bernard, A; Breittmayer, JP; Deckert, M | 1 |
| Bhattacharyya, J; Sayeed, MM; Thompson, KD | 1 |
| Azuma, EK; Kitagawa, S; Mizoguchi, H; Saito, M; Takaku, F; Umezawa, K; Yuo, A | 1 |
| Boarder, MR; Bowden, A; Brown, C; Patel, V | 1 |
| May, MJ; Morgan, AJ; Pearson, JD; Wheeler-Jones, CP | 1 |
| Cesaro, L; Dalla Via, L; Deana, R; Scapin, M; Stimamiglio, M | 1 |
| Petryniak, MA; Slack, BE; Wurtman, RJ | 1 |
| Bernstein, KE; Harp, JB; Marrero, MB; Sayeski, PP; Scanlon, M | 1 |
| Coroneos, EJ; Dunn, MJ; Kester, M; Maclouf, J; Thomas, P | 1 |
| Chien, T; Di Salvo, J; Nelson, SR | 1 |
| Ben-Yosef, D; Granot, Y; Shalgi, R; Shwartz, L; Talmor, A | 1 |
| Brenci, S; Indiveri, F; Lotti, G; Musso, NR | 1 |
| Baron, R; Chen, Y; David, JP; Dixon, SJ; Horne, WC; Inoue, D; Santhanagopal, A; Shyu, JF | 1 |
| Soltoff, SP | 1 |
| Rosado, JA; Sage, SO | 1 |
| Kitamura, T; Murayama, T; Nomura, Y | 1 |
| Baumruker, T; Csonga, R; Kikuchi, GE; Novotny, V; Prieschl, EE | 1 |
| Kalden, JR; Manger, B; Nagel, T | 1 |
| Jenner, S; Sage, SO | 1 |
| Achison, M; Barnes, MJ; Elton, CM; Farndale, RW; Hargreaves, PG; Knight, CG | 1 |
| Byron, KL; Lucchesi, PA | 1 |
| Eckert, A; Fröhlich, L; Maurer, K; Müller, WE; Schindowski, K | 1 |
| Asai, K; Hachimura, S; Kaminogawa, S; Kimura, M; Nakayama, T; Toraya, T; Yamashita, M | 1 |
| Nozu, F; Tsunoda, Y; Yoshida, H | 1 |
| Kufe, D; Li, Q; Ren, J | 1 |
| Beaudouin, J; Ellenberg, J; Gaire, M; Giannone, G; Haiech, J; Rondé, P; Takeda, K | 1 |
| Chigaev, A; Hernandez-Hansen, V; Kalesnikoff, J; Krystal, G; Lowell, CA; Mazel, T; Oliver, JM; Sklar, LA; Smith, AJ; Surviladze, Z; Wilson, BS | 1 |
| Jiang, X; Rozengurt, E; Sinnett-Smith, J | 1 |
| Inoue, K; Takano, H; Taneda, S; Yamaki, K; Yanagisawa, R; Yoshino, S | 1 |
| Clark, RA; El Jamali, A; Gamez, MJ; Lechleiter, JD; Nauseef, WM; Pearson, DW; Valente, AJ | 1 |
| Duty, JA; Farris, AD; Garman, L; Helms, C; Koelsch, KA; Mathias, M; Nakken, B; Smith, K; Swiatkowski, M; Szodoray, P; Wilson, PC; Zhang, Q; Zheng, NY | 1 |
| Bartos, JA; Beazely, MA; Chen, Y; Hell, JW; Li, H; Macdonald, JF; Ulrich, JD | 1 |
| Akahira, J; Hui, XG; Ito, S; Kudo, M; Matsuda, K; Nakamura, Y; Noguchi, N; Okamoto, H; Rainey, WE; Sasano, H; Satoh, F; Sugawara, A; Uruno, A; Yoshikawa, T | 1 |
| Jernigan, NL; Kanagy, NL; Norton, CE; Resta, TC; Walker, BR | 1 |
55 other study(ies) available for tyrosine and sq-23377
| Article | Year |
|---|---|
Variants of the mucosal mast cell line (RBL-2H3) deficient in a functional membrane glycoprotein.
Topics: Aniline Compounds; Animals; Calcium; Calcium Radioisotopes; Cell Count; Cell Cycle; Cell Line; Cell Separation; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Ionomycin; Mast Cells; Membrane Glycoproteins; Mucous Membrane; Phosphorylation; Rats; Receptors, IgE; Surface Properties; Type C Phospholipases; Tyrosine; Xanthenes | 1992 |
Intracellular calcium regulates the tyrosine kinase receptor encoded by the MET oncogene.
Topics: Blotting, Western; Calcimycin; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Ionomycin; Peptide Mapping; Phosphates; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Cell Surface; Trypsin; Tyrosine | 1991 |
Tyrosine phosphorylation is an obligatory event in IL-2 secretion.
Topics: Animals; Blotting, Western; Calcium; Concanavalin A; GTP-Binding Proteins; Interleukin-2; Ionomycin; Lymphocyte Activation; Mice; Molecular Weight; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Phytohemagglutinins; Protein-Tyrosine Kinases; T-Lymphocytes; Time Factors; Tyrosine; Virulence Factors, Bordetella | 1990 |
Angiotensin II stimulates protein-tyrosine phosphorylation in a calcium-dependent manner.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Calcium; Cell Line; Epidermal Growth Factor; Ionomycin; Kinetics; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Terpenes; Thapsigargin; Tyrosine | 1990 |
Surface immunoglobulin crosslinking activates a tyrosine kinase pathway in B cells that is independent of protein kinase C.
Topics: Animals; Antibodies, Monoclonal; B-Lymphocytes; Blotting, Western; Cross-Linking Reagents; Ionomycin; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Spleen; Tyrosine | 1991 |
Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3).
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cell Line; Complement C5a; Cross-Linking Reagents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Neutrophils; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1991 |
Mutational analysis of antigen receptor regulation of B lymphocyte growth. Evidence for involvement of the phosphoinositide signaling pathway.
Topics: Animals; B-Lymphocytes; Calcium; Cell Division; Electrophoresis, Polyacrylamide Gel; Glycosylation; GTP-Binding Proteins; Immunoglobulin M; Ionomycin; Mice; Mutation; Phorbol Esters; Phosphatidylinositols; Phosphorylation; Precipitin Tests; Receptors, Antigen; Second Messenger Systems; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1991 |
Vasoconstrictor-induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Ionomycin; Muscle, Smooth, Vascular; Norepinephrine; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate; Tyrosine; Vasoconstrictor Agents | 1991 |
Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14.
Topics: Amino Acid Sequence; Calcium; Calcium-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; Humans; Ionomycin; Molecular Sequence Data; Monocytes; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Signal Transduction; Tyrosine | 1989 |
A tyrosine phosphorylation requirement for cytotoxic T lymphocyte degranulation.
Topics: Animals; Arsenicals; Calcium; Clone Cells; Concanavalin A; Fatty Acids, Nonesterified; Genistein; Ionomycin; Isoflavones; Kinetics; Lymphocyte Activation; Mice; Molecular Weight; Oleic Acid; Oleic Acids; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line.
Topics: Animals; Benzoquinones; Catechols; Cell Division; Cell Line; Genistein; Interleukin-3; Interleukin-4; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Leukotrienes; Mast-Cell Sarcoma; Mice; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Bacterial Proteins; Dinoprostone; Endotoxins; Female; Ionomycin; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
A primary T-cell immunodeficiency associated with defective transmembrane calcium influx.
Topics: Antigens, CD; Base Sequence; Biological Transport; Calcium; Cell Membrane; Cell Nucleus; DNA-Binding Proteins; Humans; Immunologic Deficiency Syndromes; Immunophenotyping; Infant; Interleukin-2; Ionomycin; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphatidylinositols; Phospholipids; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Receptors, Antigen, T-Cell, alpha-beta; Reference Values; Substrate Specificity; T-Lymphocytes; Tyrosine | 1995 |
The effects of N-ras oncogene expression on PDGF-BB stimulated responses in cultured mouse myoblasts.
Topics: Animals; Becaplermin; Bradykinin; Calcium; Cell Line; Dexamethasone; Gene Expression; Gene Expression Regulation; Genes, ras; Ionomycin; Kinetics; Mice; Molecular Weight; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Proto-Oncogene Proteins p21(ras); Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Tyrosine | 1995 |
Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody.
Topics: Amino Acid Sequence; Animals; Cell Compartmentation; Cell Nucleus; Cells, Cultured; Cytosol; DNA-Binding Proteins; Humans; Immunologic Techniques; In Vitro Techniques; Ionomycin; Lymphocyte Activation; Mice; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; T-Lymphocytes; Tacrolimus; Transcription Factors; Tyrosine | 1995 |
Responses to T cell receptor/CD3 and interleukin-2 receptor stimulation are altered in T cells from B cell non-Hodgkin's lymphomas.
Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents; Base Sequence; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Ionophores; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, B-Cell; Molecular Sequence Data; Phosphorylation; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Tyrosine | 1995 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Opposite presynaptic regulations by glutamate through NMDA receptors of dopamine synthesis and release in rat striatal synaptosomes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Deaminase; Animals; Body Water; Dopamine; Dopamine Agents; Ergolines; Glutamates; Glutamic Acid; In Vitro Techniques; Ionomycin; Male; Models, Biological; Neostriatum; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synaptosomes; Tyrosine | 1994 |
The effect of calcium-store depletion and refilling with various bivalent cations on tyrosine phosphorylation and Mn2+ entry in fura-2-loaded human platelets.
Topics: Barium; Blood Platelets; Blotting, Western; Calcium; Densitometry; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Fura-2; Humans; Ionomycin; Manganese; Phosphorylation; Protein Tyrosine Phosphatases; Spectrometry, Fluorescence; Strontium; Tyrosine | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor.
Topics: Angiotensin II; Animals; Autoradiography; Cells, Cultured; Colforsin; Immunoblotting; Ionomycin; Male; Muscle, Smooth, Vascular; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Phenylarsine oxide and phorbol myristate acetate inhibit the CD3-induced rise of cytosolic Ca2+ in Jurkat cells by refilling internal Ca2+ stores.
Topics: Arsenicals; Biological Transport; Calcium; CD3 Complex; Cell Line; Cytosol; Ethers, Cyclic; Humans; Ionomycin; Okadaic Acid; Phosphatidylserines; Phosphorylation; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1994 |
Skeletal muscle Ca2+ flux and catabolic response during sepsis.
Topics: Animals; Bacterial Infections; Body Temperature; Calcium; Diltiazem; Eating; Ionomycin; Male; Muscles; Proteins; Rats; Rats, Sprague-Dawley; Reference Values; Tyrosine | 1993 |
Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils: no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways.
Topics: Concanavalin A; Genistein; Humans; Hydroquinones; Ionomycin; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1993 |
Evidence for requirement of tyrosine phosphorylation in endothelial P2Y- and P2U- purinoceptor stimulation of prostacyclin release.
Topics: Adenosine Triphosphate; Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Ionomycin; Phosphorylation; Protein-Tyrosine Kinases; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Stimulation, Chemical; Tyrosine; Uridine Triphosphate | 1995 |
Protein tyrosine kinases regulate agonist-stimulated prostacyclin release but not von Willebrand factor secretion from human umbilical vein endothelial cells.
Topics: Calcium; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Exocytosis; Genistein; Guanosine Monophosphate; Histamine; Humans; Ionomycin; Ionophores; Isoflavones; Phosphorylation; Protein-Tyrosine Kinases; Styrenes; Thrombin; Tyrosine; von Willebrand Factor | 1996 |
Correlation between cytosolic Ca2+ concentration, protein phosphorylation and platelet secretion.
Topics: Blood Platelets; Blood Proteins; Calcium; Calcium Chloride; Cytosol; Enzyme Inhibitors; Genistein; Humans; Ionomycin; Ionophores; Isoflavones; Myosin Light Chains; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Serotonin; Tyrosine | 1996 |
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
Topics: Amyloid beta-Protein Precursor; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Isoflavones; Kidney; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tyrosine | 1996 |
Role of intracellular calcium in the angiotensin II-mediated tyrosine phosphorylation and dephosphorylation of PLC-gamma 1.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Isoenzymes; Muscle, Smooth, Vascular; Phospholipase C gamma; Phosphorylation; Rats; Type C Phospholipases; Tyrosine | 1997 |
Calcium-regulated protein tyrosine phosphorylation is required for endothelin-1 to induce prostaglandin endoperoxide synthase-2 mRNA expression and protein synthesis in mesangial cells.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cells, Cultured; Chelating Agents; Cytosol; Endothelin-1; Enzyme Inhibitors; Gallic Acid; Gene Expression; Glomerular Mesangium; Ionomycin; Ionophores; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Proteins; Rats; RNA, Messenger; Signal Transduction; Thapsigargin; Tyrosine | 1997 |
Genistein sensitivity of calcium transport pathways in serotonin-activated vascular smooth muscle cells.
Topics: Animals; Aorta; Biological Transport; Caffeine; Calcium; Calcium Channel Blockers; Cell Line; Enzyme Inhibitors; Genistein; Immunohistochemistry; Ionomycin; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Rats; Serotonin; Thapsigargin; Tyrosine | 1997 |
Tyrosyl-phosphorylated proteins are involved in regulation of meiosis in the rat egg.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Egg Proteins; Fertilization; Ionomycin; Meiosis; Ovum; Phosphorylation; Phosphotyrosine; Rats; Rats, Wistar; Tyrosine | 1998 |
Acetylcholine-induced, calcium-dependent norepinephrine outflow from peripheral human lymphocytes.
Topics: Acetylcholine; Adult; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Gallopamil; Humans; Ionomycin; Levodopa; Lymphocytes; Male; Norepinephrine; Tyrosine; Veratridine | 1998 |
The calcitonin receptor stimulates Shc tyrosine phosphorylation and Erk1/2 activation. Involvement of Gi, protein kinase C, and calcium.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenylate Cyclase Toxin; Animals; Calcitonin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Enzyme Activation; Enzyme Inhibitors; GRB2 Adaptor Protein; GTP-Binding Proteins; Ionomycin; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Protein Kinase C; Proteins; Rabbits; Receptors, Calcitonin; Shc Signaling Adaptor Proteins; Tyrosine; Virulence Factors, Bordetella | 1998 |
Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Kinase 2; GTP-Binding Proteins; Ionomycin; Models, Biological; Nitriles; PC12 Cells; Phorbol Esters; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Quinazolines; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine; Tyrphostins; Ubiquitin-Protein Ligases; Uridine Triphosphate | 1998 |
Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.
Topics: 1-Phosphatidylinositol 4-Kinase; Actins; Blood Platelets; Blotting, Western; Calcium; Calcium-Transporting ATPases; Cation Transport Proteins; Cell Membrane; Chromones; Cytoskeleton; Enzyme Inhibitors; GTP Phosphohydrolases; Humans; Ionomycin; Ionophores; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphorylation; Plasma Membrane Calcium-Transporting ATPases; Platelet Activation; Precipitin Tests; ras Proteins; Signal Transduction; Sodium; Spectrometry, Fluorescence; Time Factors; Tyrosine | 2000 |
Enhancement of Ca2+-induced noradrenaline release by vanadate in PC12 cells: possible involvement of tyrosine phosphorylation.
Topics: Animals; Calcium; Intercellular Signaling Peptides and Proteins; Intracellular Membranes; Ionomycin; Ionophores; Norepinephrine; Osmolar Concentration; PC12 Cells; Peptides; Phosphorylation; Rats; Tetradecanoylphorbol Acetate; Tetramisole; Tyrosine; Vanadates; Wasp Venoms | 2000 |
Glycosphingolipid-induced relocation of Lyn and Syk into detergent-resistant membranes results in mast cell activation.
Topics: Adjuvants, Immunologic; Animals; Biological Transport; Bone Marrow Cells; Cell Fractionation; Cell Line; Drug Synergism; Enzyme Activation; Enzyme Precursors; Intracellular Signaling Peptides and Proteins; Ionomycin; MAP Kinase Signaling System; Mast Cells; Membrane Lipids; Mice; Octoxynol; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Psychosine; src-Family Kinases; Syk Kinase; Tyrosine | 2000 |
Co-stimulation of IL-2 production by CD28 is independent of tyrosine-based signaling motifs in a murine T cell hybridoma.
Topics: Amino Acid Sequence; Amino Acids; Animals; CD28 Antigens; Cricetinae; Gene Expression; Hybridomas; Interleukin-2; Ionomycin; Mice; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phytohemagglutinins; Protein Sorting Signals; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine | 2000 |
Two pathways for store-mediated calcium entry in human platelets.
Topics: Androstadienes; Biological Transport; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Econazole; Egtazic Acid; Enzyme Inhibitors; Humans; Imidazoles; Ionomycin; Ionophores; Lanthanum; Manganese; Phosphorylation; Protein-Tyrosine Kinases; Thapsigargin; Tyrosine; Wortmannin | 2000 |
Integrin-independent tyrosine phosphorylation of p125(fak) in human platelets stimulated by collagen.
Topics: Adult; Animals; Blood Platelets; Calcium; Cattle; Collagen; Egtazic Acid; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Integrins; Ionomycin; Ligands; Peptide Fragments; Phosphorylation; Piperazines; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Precipitin Tests; Protein Kinase C; Protein-Tyrosine Kinases; Tyrosine | 2001 |
Signal transduction of physiological concentrations of vasopressin in A7r5 vascular smooth muscle cells. A role for PYK2 and tyrosine phosphorylation of K+ channels in the stimulation of Ca2+ spiking.
Topics: Animals; Binding Sites; Blotting, Western; Calcium; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 2; Ionomycin; Ionophores; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Muscle, Smooth; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Vasopressins | 2002 |
Age-related impairment of human T lymphocytes' activation: specific differences between CD4(+) and CD8(+) subsets.
Topics: Adult; Aged; Aging; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD4 Lymphocyte Count; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Female; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Lectins, C-Type; Lymphocyte Activation; Lymphocyte Count; Male; Middle Aged; Phosphorylation; Phytohemagglutinins; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
T cell hyporesponsiveness induced by oral administration of ovalbumin is associated with impaired NFAT nuclear translocation and p27kip1 degradation.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Administration, Oral; Amino Acid Sequence; Animals; Antibody Formation; Calcium Signaling; Carrier Proteins; CD4-Positive T-Lymphocytes; Cell Cycle; Cell Cycle Proteins; Clonal Anergy; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; DNA-Binding Proteins; Dose-Response Relationship, Immunologic; Immediate-Early Proteins; Interleukin-2; Ionomycin; Isoenzymes; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Transgenic; Milk Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Ovalbumin; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-2; Spleen; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins; Type C Phospholipases; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 2002 |
Receptor-operated Ca2+ influx and its association with the Src family in secretagogue-stimulated pancreatic acini.
Topics: Amylases; Animals; Calcium; Cattle; Cholecystokinin; Enzyme Inhibitors; Fibroblast Growth Factors; Genes, src; Genistein; Humans; Ionomycin; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Recombinant Proteins; Sodium Fluoride; Tyrosine | 2004 |
Interaction of human MUC1 and beta-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells.
Topics: Amino Acid Sequence; beta Catenin; Cell Division; Cell Line, Tumor; Cell Lineage; Cell Survival; Cytoplasm; Cytoskeletal Proteins; Glutathione Transferase; Humans; Ionomycin; Ionophores; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mucin-1; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Trans-Activators; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 2004 |
Calcium rises locally trigger focal adhesion disassembly and enhance residency of focal adhesion kinase at focal adhesions.
Topics: Blotting, Western; Calcium; Cell Line, Tumor; Cell Movement; Chelating Agents; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Green Fluorescent Proteins; Humans; Ionomycin; Light; Luminescent Proteins; Lymphocytes; Microscopy, Fluorescence; Phosphorylation; Plasmids; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Signal Transduction; Time Factors; Transfection; Tyrosine | 2004 |
Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium; Cell Degranulation; Integrin alpha4beta1; Ionomycin; Mast Cells; Mice; Mice, Inbred C57BL; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phospholipase C gamma; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Receptors, IgE; Signal Transduction; src-Family Kinases; Stem Cell Factor; Type C Phospholipases; Tyrosine | 2004 |
Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells.
Topics: Angiotensins; Animals; Carbachol; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intestinal Mucosa; Ionomycin; Kinetics; Lysophospholipids; Phosphorylation; Protein Kinase C; Rats; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Tyrosine | 2007 |
Enhancement of allergic responses in vivo and in vitro by butylated hydroxytoluene.
Topics: Animals; Antioxidants; beta-N-Acetylhexosaminidases; Butylated Hydroxytoluene; Calcium; Cell Degranulation; Cell Line, Tumor; Dinitrophenols; Dose-Response Relationship, Drug; Histamine Release; Hypersensitivity; Intracellular Fluid; Ionomycin; Ionophores; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, IgE; Time Factors; Tyrosine | 2007 |
Novel redox-dependent regulation of NOX5 by the tyrosine kinase c-Abl.
Topics: Blotting, Western; Calcium; Cell Membrane; Feedback, Physiological; Green Fluorescent Proteins; Humans; Immunoblotting; Immunoprecipitation; Ionomycin; K562 Cells; Membrane Proteins; NADPH Oxidase 5; NADPH Oxidases; Oxidation-Reduction; Phosphorylation; Proto-Oncogene Proteins c-abl; Reactive Oxygen Species; Superoxides; Tyrosine | 2008 |
Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Antibodies, Monoclonal; Antigens, CD; Autoantigens; Autoimmunity; B-Lymphocyte Subsets; Calcium Signaling; Clonal Anergy; Genes, Immunoglobulin; Humans; Immunoglobulin D; Immunoglobulin M; Immunophenotyping; Ionomycin; Kinetics; Lymphocyte Activation; Mutation; Phosphorylation; Receptors, Antigen, B-Cell; Tyrosine | 2009 |
Postsynaptic clustering and activation of Pyk2 by PSD-95.
Topics: Animals; Animals, Newborn; Antibodies; Brain; Calcium; Calmodulin; Cell Line, Transformed; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Focal Adhesion Kinase 2; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ionomycin; Ionophores; Male; Membrane Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; PDZ Domains; Phosphorylation; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin; Transfection; Tyrosine | 2010 |
Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production.
Topics: Adrenal Cortex; Aldosterone; Benzophenones; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line; Cytochrome P-450 CYP11B2; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Ionomycin; Mutation; Pioglitazone; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sulfonamides; Thiazolidinediones; Transcription, Genetic; Tyrosine; Zona Glomerulosa | 2011 |
Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen species.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium-Dependent Relaxing Factors; Free Radical Scavengers; Hypertrophy, Right Ventricular; Hypocapnia; Hypoxia; Ionomycin; Lung; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Polycythemia; Pulmonary Artery; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxides; Tyrosine; Vasodilation | 2011 |