tyrosine and sphingosine 1-phosphate

tyrosine has been researched along with sphingosine 1-phosphate in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (23.53)18.2507
2000's9 (52.94)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asazuma, N; Hisano, N; Igarashi, Y; Kume, S; Ozaki, Y; Qi, R; Satoh, K; Yang, L; Yatomi, Y1
Beitner-Johnson, D; Blakesley, VA; LeRoith, D; Rani, S; Shen-Orr, Z; Spiegel, S; Stannard, BS; Van Brocklyn, JR1
Bian, ZC; Guan, JL; Guo, C; Martin-Padura, I; Zheng, C1
Nohara, K; Olivera, A; Spiegel, S; Thompson, EW; Wang, F1
Kim, KW; Kim, YM; Kim, YS; Kwon, HJ; Kwon, YG; Lee, DJ; Lee, OH1
Birukov, KG; Birukova, AA; Garcia, JG; Shikata, Y; Verin, A1
Birukov, KG; Chiang, ET; Dudek, SM; Garcia, JG; Jacobson, JR; Wang, P; Zhan, X1
Kitayama, J; Mori, K; Nagawa, H; Shida, D; Watanabe, T; Yamaguchi, H; Yamashita, H; Yatomi, Y1
Ohmori, T; Osada, M; Ozaki, Y; Yatomi, Y1
Fieger, CB; Goetzl, EJ; Huang, MC; Van Brocklyn, JR1
Fulton, D; Li, C; Ruan, L; Sood, SG; Venema, RC; Zhang, Q1
Gibbs, TC; Kipp, KR; Meier, KE; Rubio, MV; Xie, Y; Zhang, Z1
Chen, SU; Huang, YL; Lee, H; Lin, HS1
Arce, FT; Brown, ME; Camp, SM; Chiang, ET; Desai, A; Dudek, SM; Garcia, JG; Guo, Y; Imam, SZ; Lal, R; Singleton, PA; Van Eyk, JE; Wang, L; Zhao, J1
Bittman, R; Ohotski, J; Pyne, NJ; Pyne, S; Rosen, H1
Chavez, A; Desai, B; Giantsos-Adams, K; Knezevic, N; Malik, AB; Mehta, D; Rajput, C; Schmidt, TT; Sukriti, S; Yazbeck, P1
Elias, PM; Jeon, JE; Jeong, SK; Kim, BW; Kim, HJ; Kim, YI; Lee, SH; Lee, YM; Mauro, TM; Park, K; Shin, KO; Uchida, Y1

Other Studies

17 other study(ies) available for tyrosine and sphingosine 1-phosphate

ArticleYear
Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate.
    Biochemical and biophysical research communications, 1996, Dec-13, Volume: 229, Issue:2

    Topics: Blood Platelets; Enzyme Activation; Enzyme Precursors; Humans; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Phosphorylation; Platelet Activation; Protein-Tyrosine Kinases; Sphingosine; Syk Kinase; Tyrosine

1996
Sphingosine 1-phosphate stimulates tyrosine phosphorylation of Crk.
    The Journal of biological chemistry, 1997, Jun-27, Volume: 272, Issue:26

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; GRB2 Adaptor Protein; Lysophospholipids; Mice; Phosphorylation; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Sphingosine; src Homology Domains; Tyrosine

1997
Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate.
    European journal of biochemistry, 1998, Oct-15, Volume: 257, Issue:2

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Focal Adhesion Kinase 2; Lysophospholipids; Phosphorylation; Protein-Tyrosine Kinases; Rats; Sphingosine; Tyrosine

1998
Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate.
    Experimental cell research, 1999, Feb-25, Volume: 247, Issue:1

    Topics: Breast Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Movement; Chemotaxis; Collagen; Cytoskeletal Proteins; Drug Combinations; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gelatinases; Humans; Laminin; Lysophospholipids; Matrix Metalloproteinase 2; Metalloendopeptidases; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Sphingosine; Tumor Cells, Cultured; Tyrosine

1999
Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway.
    Biochemical and biophysical research communications, 2000, Feb-05, Volume: 268, Issue:1

    Topics: Cell Adhesion Molecules; Cells, Cultured; Chemotaxis; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Sphingosine; Type C Phospholipases; Tyrosine

2000
Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:15

    Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Endothelium, Vascular; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; GTPase-Activating Proteins; Humans; Lysophospholipids; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Sphingosine; Thrombin; Tyrosine

2003
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase.
    The Journal of biological chemistry, 2004, Jun-04, Volume: 279, Issue:23

    Topics: Actins; Blotting, Western; Cells, Cultured; Cortactin; Cytoskeleton; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Genes, Dominant; Genetic Vectors; GTP Phosphohydrolases; Humans; Lung; Lysophospholipids; Microfilament Proteins; Microscopy, Fluorescence; Myosin-Light-Chain Kinase; Oligonucleotides, Antisense; Peptides; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Protein Transport; Sphingosine; src Homology Domains; Time Factors; Transfection; Tyrosine

2004
Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells.
    FEBS letters, 2004, Nov-19, Volume: 577, Issue:3

    Topics: Blotting, Western; Cell Line, Tumor; ErbB Receptors; Humans; Lysophospholipids; Models, Biological; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins c-met; Sphingosine; Stomach Neoplasms; Transcriptional Activation; Tyrosine

2004
The intracellular action of sphingosine 1-phosphate in GPVI-mediated Ca2+ mobilization in platelets.
    Thrombosis research, 2005, Volume: 115, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Calcium; Calcium Signaling; Collagen; Crotalid Venoms; Humans; Lectins, C-Type; Lysophospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet Membrane Glycoproteins; Receptors, Thrombin; Sphingosine; Tyrosine

2005
Type 1 sphingosine 1-phosphate G protein-coupled receptor signaling of lymphocyte functions requires sulfation of its extracellular amino-terminal tyrosines.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:13

    Topics: Amino Acid Sequence; Animals; Blotting, Western; CD4-Positive T-Lymphocytes; Cell Movement; Cell Proliferation; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; Interferon-gamma; Jurkat Cells; Lipid Metabolism; Lipids; Lymphatic Metastasis; Lymphocytes; Lysophospholipids; Mice; Models, Biological; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Lysophospholipid; Receptors, Lysosphingolipid; Sequence Homology, Amino Acid; Signal Transduction; Sphingosine; Spleen; T-Lymphocytes; Thymus Gland; Transfection; Tyrosine

2005
Agonist-stimulated endothelial nitric oxide synthase activation and vascular relaxation. Role of eNOS phosphorylation at Tyr83.
    Circulation research, 2008, Feb-29, Volume: 102, Issue:4

    Topics: Adenosine Triphosphate; Angiopoietins; Animals; Aorta; Bradykinin; Cattle; Chlorocebus aethiops; COS Cells; Endothelial Cells; Enzyme Inhibitors; Estrogens; Humans; Kidney; Lysophospholipids; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Sprague-Dawley; Sphingosine; src-Family Kinases; Thapsigargin; Tyrosine; Vascular Endothelial Growth Factor A; Vasodilation

2008
Signal transduction responses to lysophosphatidic acid and sphingosine 1-phosphate in human prostate cancer cells.
    The Prostate, 2009, Oct-01, Volume: 69, Issue:14

    Topics: Cell Division; Cell Line, Tumor; Culture Media, Serum-Free; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Isomerism; Lysophospholipids; Male; Phosphorylation; Prostatic Neoplasms; Receptors, Lysophosphatidic Acid; Receptors, Lysosphingolipid; RNA, Messenger; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Tyrosine

2009
Tyrosine sulphation of sphingosine 1-phosphate 1 (S1P1) is required for S1P-mediated cell migration in primary cultures of human umbilical vein endothelial cells.
    Journal of biochemistry, 2009, Volume: 146, Issue:6

    Topics: Amino Acid Sequence; Blotting, Western; Cell Movement; Cells, Cultured; Endothelial Cells; Flow Cytometry; Humans; Lysophospholipids; Molecular Sequence Data; Mutation; Recombinant Proteins; Sphingosine; Sulfur; Tyrosine; Umbilical Veins

2009
Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function.
    Molecular biology of the cell, 2010, Nov-15, Volume: 21, Issue:22

    Topics: Actins; Amino Acid Sequence; Binding Sites; Blotting, Western; Capillary Permeability; Caveolins; Cell Line; Cytoskeleton; Endothelial Cells; Enzyme Activation; Green Fluorescent Proteins; Humans; Lysophospholipids; Mass Spectrometry; Membrane Microdomains; Microscopy, Atomic Force; Microscopy, Confocal; Molecular Sequence Data; Myosin-Light-Chain Kinase; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-abl; RNA Interference; Sphingosine; Tyrosine

2010
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor
    Cellular signalling, 2014, Volume: 26, Issue:5

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; CSK Tyrosine-Protein Kinase; Female; Fingolimod Hydrochloride; Humans; Lysophospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Estrogen; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; src-Family Kinases; Thiazoles; Tyrosine

2014
S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness.
    Journal of cell science, 2015, Mar-01, Volume: 128, Issue:5

    Topics: Amino Acid Substitution; Cells, Cultured; Down-Regulation; Endothelial Cells; Humans; Lysophospholipids; Mutation, Missense; Phosphorylation; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Tyrosine

2015
Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production.
    Journal of dermatological science, 2015, Volume: 79, Issue:3

    Topics: Animals; Antimicrobial Cationic Peptides; Bacterial Physiological Phenomena; Cathelicidins; Cells, Cultured; Enzyme Activators; Enzyme Inhibitors; Epidermis; Humans; Immunity, Innate; Keratinocytes; Lysophospholipids; Mice; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); RNA, Messenger; RNA, Small Interfering; Sphingosine; Staphylococcus aureus; Tyrosine

2015