tyrosine and simvastatin

tyrosine has been researched along with simvastatin in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (8.00)	18.2507
2000's	16 (64.00)	29.6817
2010's	5 (20.00)	24.3611
2020's	2 (8.00)	2.80

Authors

Authors	Studies
Hidaka, Y; Ishida, F; Kamei, T; Nagata, Y	1
Kumano, T; Kuriyama, M; Mutoh, T; Nakagawa, H	1
Bilheimer, D; Blazing, MA; Braunwald, E; Califf, RM; De Lemos, JA; Dyke, CK	1
Ceriello, A	1
Bais, B; Ceriello, A; Da Ros, R; Motz, E; Piconi, L; Quagliaro, L; Taboga, C; Tonutti, L	1
Chade, AR; Feldstein, A; Lerman, A; Lerman, LO; Napoli, C; Sawamura, T; Wilson, SH	1
Assaloni, R; Ceriello, A; Da Ros, R; Esposito, K; Giugliano, D; Maier, A; Piconi, L; Quagliaro, L	1
Coelho, OR; Franchini, KG; Lagosta, VJ; Moreno, H; Nadruz, W	1
Drucker, L; Gronich, N; Lishner, M; Radnay, J; Shapiro, H; Yarkoni, S	1
Selley, ML	1
Blazing, M; Braunwald, E; Califf, R; Cannon, CP; de Lemos, JA; McCabe, CH; Murphy, SA; Wiviott, SD	1
Brown, BG	1
Chen, S; Chew, TL; Danesh, FR; Jones, J; Kanwar, YS; Peng, H; Sadeghi, MM; Xu, H; Zeng, L	1
Blazing, MA; Braunwald, E; Califf, RM; de Lemos, JA; Morrow, DA; Rifai, N; Sabatine, MS; Shui, A; Wiviott, SD	1
Caldwell, RB; Caldwell, RW; El-Remessy, AB; Ma, G; Matragoon, S; Tawfik, HE	1
Brundel, BJ; Burstein, B; Leung, TK; Mitamura, H; Nattel, S; Ogawa, S; Shiroshita-Takeshita, A	1
Blazing, MA; Braunwald, E; Califf, RM; Cannon, CP; de Lemos, JA; McCabe, CH; Murphy, SA; Wiviott, SD	1
Banerjee, S; Blazing, MA; Braunwald, E; Brilakis, ES; Califf, RM; Cannon, CP; de Lemos, JA; Morrow, DA; Murphy, SA; Sabatine, MS; Wiviott, SD	1
Bormann, F; Czerny, C; Henrich, D; Höhn, C; Lehnert, M; Marzi, I; Relja, B; Seyboth, K	1
Andreadou, I; Farmakis, D; Fotopoulou, T; Iliodromitis, EK; Ioannidis, K; Kremastinos, DT; Paraskevaidis, IA; Prokovas, E; Zoga, A	1
Cheng, CF; Cheng, WT; Kikuchi, T; Lian, WS; Lin, H	1
Cui, GB; Liu, L; Liu, YH; Ma, B; Sun, JJ; Wu, ZM; Xu, QY; Yang, ZD; Yao, D; Zhang, Q	1
Cao, R; Dan, HC; Jiang, W; Ju, L; Qian, G; Wang, G; Wang, X; Wang, Y; Wu, M; Xiao, Y	1
Bosch, J; Cogger, VC; Fernández-Iglesias, A; Gracia-Sancho, J; Hide, D; Le Couteur, DG; Maeso-Díaz, R; Peralta, C; Warren, A	1
Han, L; Jing, W; Li, H; Liu, R; Ullah, S; Wu, X; Wu, Y; Xu, J; Yuan, L; Zhang, S	1

Reviews

1 review(s) available for tyrosine and simvastatin

Article	Year
Nitrotyrosine: new findings as a marker of postprandial oxidative stress. International journal of clinical practice. Supplement, 2002, Issue:129 Topics: Animals; Biomarkers; Diabetic Angiopathies; Endothelium, Vascular; Humans; Hyperglycemia; Hypertriglyceridemia; Hypolipidemic Agents; Oxidative Stress; Postprandial Period; Rats; Simvastatin; Tyrosine	2002

Trials

6 trial(s) available for tyrosine and simvastatin

Article	Year
The A-to-Z Trial: Methods and rationale for a single trial investigating combined use of low-molecular-weight heparin with the glycoprotein IIb/IIIa inhibitor tirofiban and defining the efficacy of early aggressive simvastatin therapy. American heart journal, 2001, Volume: 142, Issue:2 Topics: Anticoagulants; Drug Therapy, Combination; Enoxaparin; Humans; Hypolipidemic Agents; Myocardial Infarction; Patient Selection; Platelet Glycoprotein GPIIb-IIIa Complex; Research Design; Simvastatin; Tirofiban; Tyrosine	2001
Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment. Circulation, 2002, Sep-03, Volume: 106, Issue:10 Topics: Blood Glucose; Cardiovascular Diseases; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Endothelium, Vascular; Female; Glucose Tolerance Test; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Male; Middle Aged; Oxidative Stress; Postprandial Period; Risk Factors; Simvastatin; Triglycerides; Tyrosine; Vasodilation	2002
Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin treatment. Diabetes, 2004, Volume: 53, Issue:3 Topics: Body Mass Index; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; E-Selectin; Electrocardiography; Female; Humans; Hyperglycemia; Hypertriglyceridemia; Hypolipidemic Agents; Intercellular Adhesion Molecule-1; Male; Middle Aged; Oxidative Stress; Postprandial Period; Simvastatin; Triglycerides; Tyrosine; Vascular Cell Adhesion Molecule-1	2004
Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial. Circulation, 2006, Jul-25, Volume: 114, Issue:4 Topics: Acute Disease; Aged; C-Reactive Protein; Coronary Disease; Female; Follow-Up Studies; Humans; Lipoproteins, LDL; Male; Middle Aged; Prognosis; Risk Factors; Simvastatin; Survival Analysis; Tirofiban; Tyrosine	2006
Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials). The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7 Topics: Aged; Angina, Unstable; Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pravastatin; Pyrroles; Simvastatin; Tirofiban; Treatment Outcome; Tyrosine	2007
Outcomes of patients with acute coronary syndrome and previous coronary artery bypass grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials). The American journal of cardiology, 2008, Sep-01, Volume: 102, Issue:5 Topics: Atorvastatin; Coronary Artery Bypass; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Care; Pravastatin; Pyrroles; Retrospective Studies; Simvastatin; Syndrome; Thrombolytic Therapy; Time Factors; Tirofiban; Treatment Outcome; Tyrosine	2008

Other Studies

18 other study(ies) available for tyrosine and simvastatin

Article	Year
Effects of simvastatin (MK-733) on branched pathway of mevalonate. Japanese journal of pharmacology, 1990, Volume: 54, Issue:3 Topics: Animals; Anticholesteremic Agents; Cell Line; Cholesterol; DNA; Dolichols; Humans; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Proteins; Simvastatin; Thymidine; Tumor Cells, Cultured; Tyrosine; Ubiquinone	1990
Role of tyrosine phosphorylation of phospholipase C gamma1 in the signaling pathway of HMG-CoA reductase inhibitor-induced cell death of L6 myoblasts. FEBS letters, 1999, Mar-05, Volume: 446, Issue:1 Topics: Animals; Apoptosis; Cell Line; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoenzymes; Muscle, Skeletal; Phospholipase C gamma; Phosphorylation; Signal Transduction; Simvastatin; Type C Phospholipases; Tyrosine	1999
Lipid-lowering-independent effects of simvastatin on the kidney in experimental hypercholesterolaemia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:4 Topics: Analysis of Variance; Animals; Biopsy, Needle; Cholesterol, Dietary; Disease Models, Animal; Female; Hypercholesterolemia; Immunohistochemistry; Kidney; Kidney Function Tests; Nitric Oxide Synthase; Probability; Random Allocation; Receptors, LDL; Receptors, Oxidized LDL; Reference Values; Renal Circulation; Sensitivity and Specificity; Simvastatin; Swine; Tyrosine	2003
Simvastatin prevents load-induced protein tyrosine nitration in overloaded hearts. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5 Topics: Animals; Antioxidants; Aorta; Constriction; Coronary Vessels; Enzyme Induction; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Isoenzymes; Male; Membrane Transport Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Oxidative Stress; Phosphoproteins; Pressure; Proteins; Rats; Rats, Wistar; Simvastatin; Tyrosine; Ventricular Remodeling	2004
Simvastatin induces death of multiple myeloma cell lines. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2004, Volume: 52, Issue:5 Topics: Anticholesteremic Agents; Antineoplastic Agents; Apoptosis; Calcium; Cell Cycle; Cell Death; Cell Line, Tumor; Humans; Interleukin-6; Multiple Myeloma; Necrosis; Phosphorylation; Simvastatin; Tyrosine	2004
Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice. Brain research, 2005, Mar-10, Volume: 1037, Issue:1-2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cholesterol; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Microglia; Neostriatum; Nitrates; Nitric Oxide; Oxidants; Simvastatin; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine	2005
A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22. Circulation, 2006, Mar-21, Volume: 113, Issue:11 Topics: Aged; Angina, Unstable; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Case Management; Chemical and Drug Induced Liver Injury; Comorbidity; Confounding Factors, Epidemiologic; Dose-Response Relationship, Drug; Endpoint Determination; Female; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Tables; Lipids; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Risk; Risk Factors; Simvastatin; Stroke; Tirofiban; Treatment Outcome; Tyrosine	2006
Direct comparison of the A to Z and PROVE IT trials: a second chance to gain a first impression. Circulation, 2006, Mar-21, Volume: 113, Issue:11 Topics: Africa; Angioplasty, Balloon, Coronary; Asia; Atorvastatin; Australia; Canada; Case Management; Cholesterol, LDL; Confounding Factors, Epidemiologic; Dose-Response Relationship, Drug; Endpoint Determination; Europe; Heptanoic Acids; Humans; Multicenter Studies as Topic; Myocardial Ischemia; New Zealand; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Risk; Simvastatin; South America; Stents; Tirofiban; Treatment Outcome; Tyrosine; United States	2006
HMG-CoA reductase inhibitor simvastatin mitigates VEGF-induced "inside-out" signaling to extracellular matrix by preventing RhoA activation. American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:5 Topics: Actin Cytoskeleton; Actins; Animals; Cells, Cultured; Collagen Type IV; Extracellular Matrix; Focal Adhesion Protein-Tyrosine Kinases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrin beta1; Mesangial Cells; Mevalonic Acid; Phosphorylation; Proline; Rats; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Tritium; Tyrosine; Vascular Endothelial Growth Factor A	2006
Simvastatin improves diabetes-induced coronary endothelial dysfunction. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:1 Topics: Animals; Arginine; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Simvastatin; Streptozocin; Superoxides; Tyrosine; Vasodilation	2006
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure. Cardiovascular research, 2007, Apr-01, Volume: 74, Issue:1 Topics: Actins; Animals; Anti-Inflammatory Agents; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Cell Proliferation; Cells, Cultured; Dogs; Fenofibrate; Fibroblasts; Heart Atria; Heart Failure; Heart Ventricles; Hypolipidemic Agents; Models, Animal; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; PPAR alpha; Refractory Period, Electrophysiological; Simvastatin; Tyrosine; Ventricular Remodeling	2007
Simvastatin reduces mortality and hepatic injury after hemorrhage/resuscitation in rats. Shock (Augusta, Ga.), 2010, Volume: 34, Issue:1 Topics: Actins; Aldehydes; Animals; Apoptosis; Cytoskeleton; DNA Fragmentation; Hemodynamics; Hemorrhage; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Lipid Peroxidation; Liver; Male; Neutrophils; Nitric Oxide Synthase Type III; Rats; Resuscitation; Simvastatin; Tyrosine	2010
Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: possible role of oxidative/nitrosative stress attenuation. Basic research in cardiology, 2010, Volume: 105, Issue:2 Topics: Animals; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Hemodynamics; Hypercholesterolemia; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitrites; Oxidative Stress; Rabbits; Simvastatin; Tyrosine	2010
Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy. Journal of biomedical science, 2011, Apr-15, Volume: 18 Topics: Animals; Disease Models, Animal; Endothelial Cells; Fibrosis; Granulocyte Colony-Stimulating Factor; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocarditis; Simvastatin; Thrombosis; Tirofiban; Tyrosine	2011
Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. Acta pharmacologica Sinica, 2014, Volume: 35, Issue:10 Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Diet, High-Fat; Fenofibrate; Hyperlipidemias; Isoleucine; Linoleic Acid; Male; Metabolome; Metabolomics; Ornithine; Rats; Rats, Sprague-Dawley; Simvastatin; Tyrosine	2014
Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway. Scientific reports, 2016, 10-25, Volume: 6 Topics: Anilides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Enzyme Activation; Epithelial-Mesenchymal Transition; ErbB Receptors; G1 Phase Cell Cycle Checkpoints; Glycogen Synthase Kinase 3 beta; Humans; Neoplasm Invasiveness; Oxazoles; PPAR gamma; Proto-Oncogene Proteins c-akt; Simvastatin; Tyrosine; Urinary Bladder; Urinary Bladder Neoplasms	2016
Ischemia/Reperfusion Injury in the Aged Liver: The Importance of the Sinusoidal Endothelium in Developing Therapeutic Strategies for the Elderly. The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 01-20, Volume: 75, Issue:2 Topics: Age Factors; Animals; Disease Models, Animal; Endothelial Cells; Liver; Male; Nitric Oxide; Phenotype; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin; Tyrosine	2020
The Novel Interplay between Commensal Gut Bacteria and Metabolites in Diet-Induced Hyperlipidemic Rats Treated with Simvastatin. Journal of proteome research, 2022, 03-04, Volume: 21, Issue:3 Topics: Animals; Bacteria; Diet; Feces; Linoleic Acids; Metabolomics; Phenylalanine; Rats; RNA, Ribosomal, 16S; Simvastatin; Tandem Mass Spectrometry; Tyrosine	2022