tyrosine and sb 203580

tyrosine has been researched along with sb 203580 in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (23.08)18.2507
2000's25 (64.10)29.6817
2010's5 (12.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foltz, IN; Lee, JC; Schrader, JW; Young, PR1
Cohen, MV; Downey, JM; Liu, GS; Weinbrenner, C1
Aiboshi, J; Johnson, JL; Moore, EE; Silliman, CC; Tamura, DY; Zallen, G1
Bansal, V; Detmers, PA; Hanlon, WA; Polizzi, E; Thieringer, R; Vaidya, S; Zhou, D1
Gon, Y; Hashimoto, S; Horie, T; Matsumoto, K; Nakayama, T; Takeshita, I1
Marshall, CJ; Rausch, O1
Hajjar, JJ; Molski, TF; Nagarkatti, D; Sha'afi, RI; Syrbu, SI; Waterman, WH1
Frank, DA; Gollob, JA; Murphy, EA; Ritz, J; Schnipper, CP1
Adams, JL; Jiang, MS; Kumar, S; Lee, JC1
Gon, Y; Hashimoto, S; Horie, T; Jibiki, I; Kudoh, S; Matsumoto, K; Takeshita, I; Takizawa, H1
Hazan-Halevy, I; Levy, R; Seger, R1
Mackay, K; Mochly-Rosen, D1
Adams, JL; Dillon, SB; Griego, SD; Tal-Singer, R; Weston, CB1
Fennelly, C; Krause, D; Lyons, A; O'Connor, R1
Brar, BK; Knight, RA; Latchman, DS; Matsumura, M; Nakanishi, Y; Scarabelli, TM; Stephanou, A1
Fish, EN; Fujita, S; Grumbach, IM; Lekmine, F; Majchrzak, B; Mayer, IA; Platanias, LC; Ravandi, F; Uddin, S; Verma, A1
Chu, AJ; Seto, A; Walton, MA; Wang, ZG1
Ishida, N; Kim, S; Miyazaki, H; Miyazaki, K; Shimizu, H; Shiota, M; Yamada, N1
Dey, CS; Kumar, N2
Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH1
Berti, E; Burlando, B; Magnelli, V; Panfoli, I; Viarengo, A1
Chain, BM; Cho, JY; Katz, DR1
Bazuine, M; Gomes de Mesquita, DS; Maassen, JA; Ouwens, DM1
Barrett, KE; Carlstrom, K; Chow, JY1
Ambruso, DR; Anderson, SM; Elzi, DJ; Kelher, MR; Paterson, AJ; Silliman, CC; Thurman, GW1
Han, J; Schnellmann, RG; Yan, Y; Zhuang, S1
Li, SN; Miyazu, M; Naruse, K; Sokabe, M; Wang, JG; Xiang, P1
Lin, C; Liu, ZR; Yang, L1
Blondeau, JP; Corrèze, C; Pomérance, M1
Foster, GH; Rubin, BK; Shinkai, M1
Ferjan, I; Stempelj, M1
Ba, ZF; Bland, KI; Chaudry, IH; Chen, J; Choudhry, MA; Hsu, JT; Kan, WH; Schwacha, MG1
Cancedda, FD; Cancedda, R; Ulivi, V1
Avkiran, M; Bassi, R; Clark, JE; Jacquet, S; Kumphune, S; Marber, MS; O'Keefe, SJ; Sicard, P; Verma, S1
Chen, TH; Chiou, YL; Huang, YC; Li, TT; Liu, KC; Liu, LL; Yang, CH1
Hsia, TC; Liu, CL; Yin, MC1
Chen, XQ; Lü, J; Wang, MJ; Wu, SH1
Cong, H; Fan, B; Gu, J; Wang, T; Zhong, W1

Other Studies

39 other study(ies) available for tyrosine and sb 203580

ArticleYear
Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway.
    The Journal of biological chemistry, 1997, Feb-07, Volume: 272, Issue:6

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Interleukin-4; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Ribosomal Protein S6 Kinases; Stem Cell Factor; Tyrosine

1997
Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:9

    Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Densitometry; Enzyme Activation; Enzyme Inhibitors; Heart; Hemodynamics; Imidazoles; Ischemic Preconditioning, Myocardial; Mitogen-Activated Protein Kinases; Models, Statistical; Myocardial Ischemia; Myocardium; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rabbits; Tyrosine

1997
p38 mitogen-activated protein kinase inhibition attenuates intercellular adhesion molecule-1 up-regulation on human pulmonary microvascular endothelial cells.
    Surgery, 1998, Volume: 124, Issue:2

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Capillaries; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Lung; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation

1998
Role of stress-activated mitogen-activated protein kinase (p38) in beta 2-integrin-dependent neutrophil adhesion and the adhesion-dependent oxidative burst.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Aug-15, Volume: 161, Issue:4

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Immunologic; Enzyme Inhibitors; Fibrinogen; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Respiratory Burst; Stress, Physiological; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine

1998
Hyperosmolarity-induced interleukin-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase.
    American journal of respiratory and critical care medicine, 1999, Volume: 159, Issue:2

    Topics: Blotting, Northern; Blotting, Western; Bronchi; Bronchial Hyperreactivity; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gene Expression; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Mannitol; Mitogen-Activated Protein Kinases; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger; Saline Solution, Hypertonic; Signal Transduction; Tyrosine

1999
Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation.
    The Journal of biological chemistry, 1999, Feb-12, Volume: 274, Issue:7

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Imidazoles; Interleukin-3; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; ras Proteins; Receptors, Granulocyte Colony-Stimulating Factor; Tyrosine

1999
Phosphorylation of cytosolic phospholipase A2 and the release of arachidonic acid in human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-15, Volume: 162, Issue:4

    Topics: Acyltransferases; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Microsomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Pyridines; Tumor Necrosis Factor-alpha; Tyrosine

1999
The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Apr-15, Volume: 162, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CD18 Antigens; CD8 Antigens; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Humans; Imidazoles; Interleukin-12; Interleukin-2; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Serine; STAT1 Transcription Factor; STAT3 Transcription Factor; T-Lymphocyte Subsets; Trans-Activators; Tyrosine

1999
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase.
    Biochemical and biophysical research communications, 1999, Oct-05, Volume: 263, Issue:3

    Topics: Animals; Cell Line; COS Cells; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Kinetics; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Recombinant Proteins; Threonine; Transfection; Tyrosine

1999
Diesel exhaust particles activate p38 MAP kinase to produce interleukin 8 and RANTES by human bronchial epithelial cells and N-acetylcysteine attenuates p38 MAP kinase activation.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:1

    Topics: Acetylcysteine; Blotting, Western; Bronchi; Cells, Cultured; Chemokine CCL5; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Imidazoles; Interleukin-8; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Threonine; Tyrosine; Vehicle Emissions

2000
The requirement of both extracellular regulated kinase and p38 mitogen-activated protein kinase for stimulation of cytosolic phospholipase A(2) activity by either FcgammaRIIA or FcgammaRIIIB in human neutrophils. A possible role for Pyk2 but not for the G
    The Journal of biological chemistry, 2000, Apr-28, Volume: 275, Issue:17

    Topics: Antigens, CD; Cytosol; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Immunoblotting; Mitogen-Activated Protein Kinases; Models, Biological; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Binding; Pyridines; Receptors, IgG; Signal Transduction; Superoxides; Time Factors; Tyrosine; Zymosan

2000
Involvement of a p38 mitogen-activated protein kinase phosphatase in protecting neonatal rat cardiac myocytes from ischemia.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:8

    Topics: Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Ischemia; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine; Vanadates

2000
Role of p38 mitogen-activated protein kinase in rhinovirus-induced cytokine production by bronchial epithelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Nov-01, Volume: 165, Issue:9

    Topics: Bronchi; Cell Line; Cytokines; Enzyme Inhibitors; Epithelial Cells; HeLa Cells; Humans; Imidazoles; Interleukin-1; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Picornaviridae Infections; Pyridines; Rhinovirus; RNA, Messenger; Tyrosine; Ultraviolet Rays; Virus Activation

2000
Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: Anisomycin; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Cytoskeleton; Dicumarol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Insulin Receptor Substrate Proteins; Interleukin-3; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Pyridines; Receptor, IGF Type 1; Recombinant Proteins; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine

2001
Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701.
    The Journal of biological chemistry, 2001, Jul-27, Volume: 276, Issue:30

    Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cells, Cultured; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Imidazoles; In Situ Nick-End Labeling; Membrane Glycoproteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Pyridines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serine; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Transcriptional Activation; Transfection; Tyrosine

2001
The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
    The Journal of biological chemistry, 2001, Jul-27, Volume: 276, Issue:30

    Topics: Androstadienes; Cell Division; Cell Line; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Genistein; Humans; Imidazoles; Immunoblotting; Interferon-alpha; Intracellular Signaling Peptides and Proteins; K562 Cells; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Tyrosine; Wortmannin

2001
Involvement of MAPK activation in bacterial endotoxin-inducible tissue factor upregulation in human monocytic THP-1 cells.
    The Journal of surgical research, 2001, Volume: 101, Issue:1

    Topics: Cell Line; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Genistein; Humans; Imidazoles; Isoenzymes; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Monocytes; Phosphorylation; Pyridines; Thromboplastin; Tyrosine; Up-Regulation

2001
Low M(r) protein tyrosine phosphatase inhibits growth and migration of vascular smooth muscle cells induced by platelet-derived growth factor.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adenoviridae; Animals; Cell Division; Cell Movement; Cells, Cultured; Cloning, Molecular; Cytoplasm; DNA; DNA, Complementary; Enzyme Inhibitors; Imidazoles; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Binding; Protein Tyrosine Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Tyrosine

2001
Metformin enhances insulin signalling in insulin-dependent and-independent pathways in insulin resistant muscle cells.
    British journal of pharmacology, 2002, Volume: 137, Issue:3

    Topics: Animals; Cells, Cultured; Deoxyglucose; Hypoglycemic Agents; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Metformin; Mice; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyridines; Receptor, Insulin; Signal Transduction; Tyrosine

2002
Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells.
    The Journal of experimental biology, 2002, Volume: 205, Issue:Pt 23

    Topics: Animals; Cell Line; Deoxyglucose; Enzyme Inhibitors; Gliclazide; Hypoglycemic Agents; Imidazoles; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyridines; Receptor, Insulin; Signal Transduction; Tyrosine

2002
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
    American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:6

    Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

2002
Ligand-independent tyrosine kinase signalling in RTH 149 trout hepatoma cells: comparison among heavy metals and pro-oxidants.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2003, Volume: 13, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Copper; DNA-Binding Proteins; Dose-Response Relationship, Drug; Genistein; Hydrogen Peroxide; Imidazoles; Ligands; Mercury; Metals, Heavy; Milk Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Receptor Protein-Tyrosine Kinases; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Tyrosine

2003
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells

2003
Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity.
    European journal of biochemistry, 2003, Volume: 270, Issue:19

    Topics: 3T3 Cells; Adipocytes; Animals; Arsenites; Biological Transport; Caveolin 1; Caveolins; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Imidazoles; Insulin; Mice; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Oncogene Protein v-cbl; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Pyridines; Receptor, Insulin; Retroviridae Proteins, Oncogenic; Signal Transduction; Tyrosine

2003
Growth hormone reduces chloride secretion in human colonic epithelial cells via EGF receptor and extracellular regulated kinase.
    Gastroenterology, 2003, Volume: 125, Issue:4

    Topics: Biological Transport; Carbachol; Cell Line; Chlorides; Cholinergic Agonists; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; Human Growth Hormone; Humans; Imidazoles; Intestinal Mucosa; Janus Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Tyrosine

2003
Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils.
    Cell calcium, 2003, Volume: 34, Issue:6

    Topics: Calcium; Cytosol; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; I-kappa B Proteins; Imidazoles; Mitogen-Activated Protein Kinases; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Transcription Factors; Tyrosine

2003
p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Adenoviridae; Animals; beta Catenin; Cell Differentiation; Cell Movement; Cell Proliferation; Cytoskeletal Proteins; Enzyme Inhibitors; Epithelial Cells; Epithelium; ErbB Receptors; Humans; Hydrogen Peroxide; Imidazoles; Immunoblotting; Immunohistochemistry; Kidney; Kidney Tubules; MAP Kinase Kinase 3; Oxidants; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proteins; Pyridines; Rabbits; Signal Transduction; src-Family Kinases; Time Factors; Trans-Activators; Transcriptional Activation; Tyrosine; Ultraviolet Rays; Vimentin

2005
Stretch-induced cell proliferation is mediated by FAK-MAPK pathway.
    Life sciences, 2005, Apr-29, Volume: 76, Issue:24

    Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Fibroblasts; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Immunoblotting; Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Rats; Signal Transduction; Stress, Mechanical; Tyrosine

2005
Signaling to the DEAD box--regulation of DEAD-box p68 RNA helicase by protein phosphorylations.
    Cellular signalling, 2005, Volume: 17, Issue:12

    Topics: DEAD-box RNA Helicases; HeLa Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Pyridines; RNA Helicases; Signal Transduction; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine

2005
p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells.
    European journal of endocrinology, 2005, Volume: 153, Issue:1

    Topics: Animals; CDC2-CDC28 Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclin-Dependent Kinase 2; Enzyme Inhibitors; G1 Phase; Hypoglycemic Agents; Imidazoles; Insulin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; S Phase; Signal Transduction; Threonine; Thyroid Gland; Tyrosine

2005
Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:1

    Topics: Anti-Bacterial Agents; Azithromycin; Bronchi; Cells, Cultured; Clarithromycin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reference Values; Threonine; Time Factors; Tyrosine

2006
Signaling pathway in nerve growth factor induced histamine release from rat mast cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2005, Volume: 54, Issue:8

    Topics: Analysis of Variance; Androstadienes; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Flavonoids; Histamine; Imidazoles; Indoles; Male; Maleimides; Mast Cells; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tyrosine; Wortmannin

2005
p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6

    Topics: Abdomen; Animals; Calmodulin; Cardiotonic Agents; Caveolin 1; Chemokine CXCL1; Chemokine CXCL2; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Estradiol; Heart Diseases; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Mitogen-Activated Protein Kinase 11; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peroxidase; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation; Ventricular Function

2008
15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation.
    Journal of cellular physiology, 2008, Volume: 217, Issue:2

    Topics: Acute-Phase Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Cartilage; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Diclofenac; Dinoprostone; Down-Regulation; Enzyme Induction; Enzyme Repression; Imidazoles; Inflammation; Intramolecular Oxidoreductases; Lipocalin-2; Lipocalins; Lipopolysaccharides; Mice; NF-kappa B; Oncogene Proteins; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; PPAR alpha; PPAR gamma; Prostaglandin D2; Prostaglandin-E Synthases; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Time Factors; Tyrosine

2008
A chemical genetic approach reveals that p38alpha MAPK activation by diphosphorylation aggravates myocardial infarction and is prevented by the direct binding of SB203580.
    The Journal of biological chemistry, 2010, Jan-29, Volume: 285, Issue:5

    Topics: Animals; Enzyme Activation; Humans; Imidazoles; Male; MAP Kinase Signaling System; Mice; Mice, Transgenic; Models, Biological; Myocardial Infarction; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Isoforms; Pyridines; Tyrosine

2010
Fenofibrate suppresses melanogenesis in B16-F10 melanoma cells via activation of the p38 mitogen-activated protein kinase pathway.
    Chemico-biological interactions, 2013, Oct-05, Volume: 205, Issue:3

    Topics: Blotting, Western; Cell Line, Tumor; Cell Survival; Fenofibrate; Humans; Imidazoles; MAP Kinase Signaling System; Melanins; Melanoma, Experimental; Microphthalmia-Associated Transcription Factor; Oxazoles; PPAR alpha; Pyridines; Real-Time Polymerase Chain Reaction; RNA; Tyrosine

2013
s-Methyl cysteine enhanced survival of nerve growth factor differentiated PC12 cells under hypoxic conditions.
    Food & function, 2014, Volume: 5, Issue:6

    Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Caspase 8; Cell Differentiation; Cell Survival; Cysteine; DNA Fragmentation; Dose-Response Relationship, Drug; Glutathione Peroxidase; Glutathione Reductase; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Indazoles; Membrane Potential, Mitochondrial; Nerve Growth Factor; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Pyridines; Pyrrolidines; Rats; Reactive Oxygen Species; Thiocarbamates; Tyrosine; Up-Regulation

2014
BML-111 Attenuates Renal Ischemia/Reperfusion Injury Via Peroxisome Proliferator-Activated Receptor-α-Regulated Heme Oxygenase-1.
    Inflammation, 2016, Volume: 39, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cell Line; Creatinine; Glucuronidase; Heme Oxygenase-1; Heptanoic Acids; Imidazoles; Leucyl Aminopeptidase; Male; Malondialdehyde; Oxazoles; p38 Mitogen-Activated Protein Kinases; Peroxidase; Phosphorylation; PPAR alpha; Promoter Regions, Genetic; Protoporphyrins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Reperfusion Injury; RNA, Messenger; Tyrosine

2016
Oleic acid-induced perilipin 5 expression and lipid droplets formation are regulated by the PI3K/PPARα pathway in HepG2 cells.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2019, Volume: 44, Issue:8

    Topics: Azo Compounds; Chromones; Gene Expression Regulation; Hep G2 Cells; Humans; Imidazoles; Lipid Droplets; Morpholines; Oleic Acid; Oxazoles; Perilipin-5; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PPAR alpha; Pyridines; Staining and Labeling; Sulfones; Thiophenes; Tyrosine

2019