tyrosine and psammaplin a

tyrosine has been researched along with psammaplin a in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (4.08)	18.2507
2000's	18 (36.73)	29.6817
2010's	28 (57.14)	24.3611
2020's	1 (2.04)	2.80

Authors

Authors	Studies
Jung, JH; Lee, CO; Sim, CJ	1
Jung, JH; Kim, D; Lee, IS; Yang, SI	1
Matsunaga, K; Ohizumi, Y; Shin, H; Shizuri, Y; Suzuki, A; Tabudrav, J	1
Barluenga, S; Hughes, R; Nicolaou, KC; Pfefferkorn, JA; Roecker, AJ	1
Barluenga, S; Hughes, R; Nicolaou, KC; Pfefferkorn, JA	1
Eijsink, VG; Gooday, GW; Jaspars, M; Komander, D; Legg, M; Synstad, B; Tabudravu, JN; van Aalten, DM	1
Bair, KW; Cornell-Kennon, S; Crews, P; France, D; Gautschi, JT; Perez, LB; Piña, IC; Remiszewski, SW; Sambucetti, LC; Sanders, ML; Schmitz, FJ; Wang, GY	1
Cho, H; Hong, J; Im, KS; Jung, JH; Kim, DK; Lee, CO; Liu, Y; Park, Y	1
Kwon, HJ; Lee, HS; Shim, JS; Shin, J	1
Ahn, EY; Jiang, Y; Jung, JH; Kim, DK; Lee, BJ; Lee, DS; Park, JS; Ryu, SH; Yoon, HJ; You, S	1
Andersen, OA; Dixon, MJ; Eggleston, IM; van Aalten, DM	1
Bauvois, B; Dauzonne, D	1
Angelino, N; Godert, AM; James, SR; Karpf, AR; Morey, SR; Sufrin, JR; Woloszynska-Read, A	1
Avery, MA; Desai, PV; Feller, DR; Jones, DK; Mora, FD; Nagle, DG; Patny, A; Smillie, T; Zhou, YD	1
Dubois, F; Giordanengo, P; Laberche, JC; Saguez, J; Sangwan-Norreel, BS; Vincent, C	1
Kim, DH; Kwon, HJ; Shin, J	1
Ahn, MY; Jung, JH; Kim, HS; Na, YJ	1
Schupp, PJ; Thoms, C	1
Fu, LW; Zhang, JY	1
Banerjee, N; Bugni, TS; Cannon, KM; Coombs, GS; Harper, MK; Ireland, CM; McCulloch, MW; Veltri, CA; Virshup, DM	1
Baud, MG; Fuchter, MJ; Leiser, T; Meyer-Almes, FJ	1
Hu, G; Liu, D; Sun, D; Wu, Z; Yang, Q; Yang, S; Zhao, L	1
Altucci, L; Benedetti, R; de Lera, AR; Franci, G; García, J; Gronemeyer, H; Nebbioso, A; Pereira, R; Rodríguez-Barrios, F	1
Cherqui, A; De Pauw, E; Dommès, J; Francis, F; Giordanengo, P; Haubruge, E; Saguez, J; Vandermoten, S; Versali, MF; Vincent, C	1
Baud, MG; Buluwela, L; Fuchter, MJ; Gunaratnam, M; Haus, P; Hughes, SM; Leiser, T; Meyer-Almes, FJ; Neidle, S; Petrucci, V; Samlal, S; Turlais, F; White, AJ; Wong, AC; Wood, RJ	1
Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD	1
Hentschel, F; Lindel, T; Sasse, F	1
Altucci, L; Benedetti, R; Carafa, V; Conte, M; de Lera, AR; García-Rodríguez, J; Gronemeyer, H; Nebbioso, A; Pereira, R; Pérez-Rodríguez, S; Rodríguez-Barrios, F; Stuhldreier, M; Stunnenberg, HG	1
Joo, SH; Kim, HJ; Kim, IH; Kim, TH; Ma, ES; Park, ES; Seo, WS; Shin, BS; Shin, S; Yoo, SD	1
Baud, MG; Fuchter, MJ; Haus, P; Leiser, T; Meyer-Almes, FJ	1
Akimitsu, N; Furuta, A; Moriishi, K; Nakakoshi, M; Noda, N; Salam, KA; Sekiguchi, Y; Tanaka, J; Tani, H; Tsubuki, M; Tsuneda, S; Yamashita, A	1
Hiusen, TJ; Kamble-Shripat, T	1
Ibáñez, E; Mallol, A; Santaló, J	1
Choi, WS; Jung, JH; Kang, YJ; Kim, HS; Kim, TH; Lee, J; Yoon, S	1
Ha, MW; Hong, S; Jung, M; Lee, SK; Lee, YJ; Oh, KB; Park, HG; Park, Y; Shin, J; Shin, Y	1
Lin, W; Marmann, A; Niemann, H; Proksch, P	1
Cho, HJ; Ha, MW; Kim, DD; Lee, JY; Lee, MY; Park, HG; Shin, J; Won, TH	1
Ibáñez, E; Mallol, A; Piqué, L; Santaló, J	1
Choi, SH; Jung, JH; Kim, TS; Lee, A; Lee, BC	1
Bao, Y; Fan, Y; Jiang, T; Li, K; Liu, D; Liu, J; Niu, Q; Wang, J; Wang, W; Wen, J; Yang, J; Zhao, L	1
Al Mamun Bhuyan, A; Lang, F; Signoretto, E	1
Ratovitski, EA	1
Artali, R; Bianchino, E; Cardile, F; Cincinelli, R; Colelli, F; Dallavalle, S; Guglielmi, M; Musso, L; Pisano, C	1
Andersen, RJ; Brockman, MA; Brumme, ZL; de Silva, ED; Richard, K; Tietjen, I; Williams, DE	1
Chen, WL; Du, L; Le, TP; Li, J; Mahdi, F; Nagle, DG; Swanson, SM; Watabe, K; Zhou, YD	1
Andjouh, S; Blache, Y	1
Lei, X; Li, Y; Ruan, ZW; Shan, G; Yu, X; Zhang, B; Zheng, Y	1
Bai, J; Hu, X; Hua, H; Jing, Q; Li, D; Li, Z; Liu, W; Ma, Y; Mu, J; Xu, F	1
Diyaolu, O; Ebel, R; Goh, TMB; Jaspars, M; Katermeran, NP; Oluwabusola, ET; Poh, WH; Rice, SA; Tabudravu, J; Tan, LT	1

Reviews

5 review(s) available for tyrosine and psammaplin a

Article	Year
Natural product family 18 chitinase inhibitors. Natural product reports, 2005, Volume: 22, Issue:5 Topics: Acetylglucosamine; Biological Factors; Chitinases; Dipeptides; Disulfides; Enzyme Inhibitors; Molecular Structure; Peptides, Cyclic; Proline; Trisaccharides; Tyrosine; Xanthines	2005
Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects. Medicinal research reviews, 2006, Volume: 26, Issue:1 Topics: Animals; Betulinic Acid; CD13 Antigens; Cell Proliferation; Curcumin; Disulfides; Humans; Hydroxamic Acids; Leucine; Neovascularization, Physiologic; Neprilysin; Oligopeptides; Pentacyclic Triterpenes; Protease Inhibitors; Triterpenes; Tyrosine	2006
[Advance of several types of important marine antitumor drugs]. Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Bryostatins; Cell Line, Tumor; Depsipeptides; Dioxoles; Disulfides; Ethers, Cyclic; Humans; Macrolides; Marine Biology; Neoplasms; Tetrahydroisoquinolines; Trabectedin; Tyrosine	2008
Sponge derived bromotyrosines: structural diversity through natural combinatorial chemistry. Natural product communications, 2015, Volume: 10, Issue:1 Topics: Acetonitriles; Animals; Cyclohexenes; Disulfides; Drug Discovery; Ecosystem; Humans; Molecular Structure; Porifera; Tyrosine	2015
Marine-Derived Natural Lead Compound Disulfide-Linked Dimer Psammaplin A: Biological Activity and Structural Modification. Marine drugs, 2019, Jun-27, Volume: 17, Issue:7 Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Antiviral Agents; Aquatic Organisms; Biological Products; Cell Line, Tumor; Disulfides; Eryptosis; Humans; Insecticides; Molecular Structure; Porifera; Structure-Activity Relationship; Tyrosine	2019

Other Studies

44 other study(ies) available for tyrosine and psammaplin a

Article	Year
Cytotoxic compounds from a two-sponge association. Journal of natural products, 1995, Volume: 58, Issue:11 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Disulfides; Drug Screening Assays, Antitumor; Furans; Humans; Macrolides; Phenylpropionates; Porifera; Pyrans; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Tyrosine	1995
Psammaplin A, a natural bromotyrosine derivative from a sponge, possesses the antibacterial activity against methicillin-resistant Staphylococcus aureus and the DNA gyrase-inhibitory activity. Archives of pharmacal research, 1999, Volume: 22, Issue:1 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Colony Count, Microbial; Disulfides; DNA, Bacterial; Enzyme Inhibitors; Hexosyltransferases; Methicillin Resistance; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Phenylpropionates; Porifera; Staphylococcus aureus; Topoisomerase II Inhibitors; Tyrosine	1999
Bisprasin, a novel Ca(2+) releaser with caffeine-like properties from a marine sponge, Dysidea spp., acts on Ca(2+)-induced Ca(2+) release channels of skeletal muscle sarcoplasmic reticulum. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2 Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channel Blockers; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Magnesium; Male; Muscle, Skeletal; Porifera; Procaine; Protein Binding; Rabbits; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors; Tyrosine	2000
Combinatorial synthesis through disulfide exchange: discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry (Weinheim an der Bergstrasse, Germany), 2001, Oct-01, Volume: 7, Issue:19 Topics: Anti-Bacterial Agents; Combinatorial Chemistry Techniques; Dimerization; Disulfides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship; Tyrosine	2001
Optimization and mechanistic studies of psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry (Weinheim an der Bergstrasse, Germany), 2001, Oct-01, Volume: 7, Issue:19 Topics: Anti-Bacterial Agents; Combinatorial Chemistry Techniques; Dimerization; Disulfides; Methicillin Resistance; Microbial Sensitivity Tests; Oximes; Staphylococcus aureus; Structure-Activity Relationship; Tyrosine	2001
Psammaplin A, a chitinase inhibitor isolated from the Fijian marine sponge Aplysinella rhax. Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:4 Topics: Animals; Antifungal Agents; Catalytic Domain; Chitinases; Disulfides; Enzyme Inhibitors; Insecta; Insecticides; Kinetics; Molecular Structure; Plant Proteins; Porifera; Spores, Fungal; Tyrosine	2002
Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase. The Journal of organic chemistry, 2003, May-16, Volume: 68, Issue:10 Topics: Animals; Disulfides; DNA Modification Methylases; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Papua New Guinea; Porifera; Sulfuric Acid Esters; Tyrosine	2003
New bromotyrosine derivatives from an association of two sponges, Jaspis wondoensis and Poecillastra wondoensis. Journal of natural products, 2003, Volume: 66, Issue:11 Topics: Animals; Antineoplastic Agents, Phytogenic; Central Nervous System Neoplasms; Colonic Neoplasms; Disulfides; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; Female; Humans; Korea; Lung Neoplasms; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Ovarian Neoplasms; Porifera; Skin Neoplasms; Staphylococcus; Tumor Cells, Cultured; Tyrosine	2003
Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro. Cancer letters, 2004, Jan-20, Volume: 203, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Capillaries; Cattle; CD13 Antigens; Cell Division; Cell Line, Tumor; Cells, Cultured; Disulfides; Dose-Response Relationship, Drug; Endothelial Cells; Fibroblast Growth Factor 2; In Vitro Techniques; Inhibitory Concentration 50; Models, Chemical; Neoplasm Invasiveness; Neovascularization, Pathologic; Porifera; Tyrosine	2004
Cytotoxicity of psammaplin A from a two-sponge association may correlate with the inhibition of DNA replication. BMC cancer, 2004, Sep-30, Volume: 4 Topics: Animals; Cell Line, Tumor; Cell Survival; Disulfides; DNA Polymerase I; DNA Primase; DNA Replication; Drug Screening Assays, Antitumor; Porifera; Simian virus 40; Topoisomerase II Inhibitors; Tyrosine; Virus Replication	2004
An improved synthesis of psammaplin A. Bioorganic & medicinal chemistry letters, 2006, Jun-15, Volume: 16, Issue:12 Topics: Cell Line, Tumor; Disulfides; DNA Methylation; Enzyme Inhibitors; Humans; Methyltransferases; Molecular Structure; Tyrosine	2006
Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-gamma (PPARgamma): the marine sponge metabolite psammaplin A activates PPARgamma and induces apoptosis in human breast tumor cells. Journal of natural products, 2006, Volume: 69, Issue:4 Topics: Animals; Apoptosis; Breast Neoplasms; Disulfides; Dose-Response Relationship, Drug; Female; Histone Deacetylase Inhibitors; Humans; Micronesia; Porifera; PPAR gamma; Tyrosine	2006
Differential aphicidal effects of chitinase inhibitors on the polyphagous homopteran Myzus persicae (Sulzer). Pest management science, 2006, Volume: 62, Issue:12 Topics: Acetylglucosamine; Animals; Aphids; Chitinases; Disulfides; Female; Insecticides; Trisaccharides; Tyrosine	2006
Psammaplin A is a natural prodrug that inhibits class I histone deacetylase. Experimental & molecular medicine, 2007, Feb-28, Volume: 39, Issue:1 Topics: Acetylation; Biological Products; Cell Proliferation; Disulfides; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Molecular Structure; Oxidation-Reduction; Prodrugs; Tyrosine	2007
A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells. Gynecologic oncology, 2008, Volume: 108, Issue:1 Topics: Acetylation; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Disulfides; Dose-Response Relationship, Drug; Endometrial Neoplasms; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histones; Humans; Tyrosine	2008
Activated chemical defense in marine sponges--a case study on Aplysinella rhax. Journal of chemical ecology, 2008, Volume: 34, Issue:9 Topics: Adaptation, Physiological; Animals; Disulfides; Feeding Behavior; Models, Biological; Molecular Structure; Porifera; Predatory Behavior; Tetraodontiformes; Tyrosine; Wound Healing	2008
Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6 Topics: Animals; Cell Line; Disulfides; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Magnetic Resonance Spectroscopy; Porifera; Signal Transduction; Tyrosine	2009
New synthetic strategies towards psammaplin A, access to natural product analogues for biological evaluation. Organic & biomolecular chemistry, 2011, Feb-07, Volume: 9, Issue:3 Topics: Biological Products; Disulfides; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydrolysis; Inhibitory Concentration 50; Molecular Structure; Oxazolone; Structure-Activity Relationship; Tyrosine	2011
Synthesis of the marine bromotyrosine psammaplin F and crystal structure of a psammaplin A analogue. Molecules (Basel, Switzerland), 2010, Dec-02, Volume: 15, Issue:12 Topics: Animals; Crystallography, X-Ray; Disulfides; Molecular Structure; Porifera; Tyrosine	2010
Epigenetic profiling of the antitumor natural product psammaplin A and its analogues. Bioorganic & medicinal chemistry, 2011, Jun-15, Volume: 19, Issue:12 Topics: Acetylation; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Disulfides; Drug Screening Assays, Antitumor; Epigenomics; Histones; Humans; Ligands; Molecular Dynamics Simulation; Protein Array Analysis; Tubulin; Tyrosine	2011
Purification and characterisation of a 31-kDa chitinase from the Myzus Persicae aphid: a target for hemiptera biocontrol. Applied biochemistry and biotechnology, 2012, Volume: 166, Issue:5 Topics: Acetylglucosamine; Animals; Aphids; Chitinases; Disulfides; Enzyme Inhibitors; Molecular Weight; Pest Control, Biological; Trisaccharides; Tyrosine	2012
Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets. Journal of medicinal chemistry, 2012, Feb-23, Volume: 55, Issue:4 Topics: Acetylation; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Dimerization; Disulfides; DNA (Cytosine-5-)-Methyltransferases; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Humans; Isoenzymes; Models, Molecular; Prodrugs; Structure-Activity Relationship; Tubulin; Tyrosine	2012
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity. Radiation oncology (London, England), 2012, Mar-20, Volume: 7 Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine	2012
Fluorescent analogs of the marine natural product psammaplin A: synthesis and biological activity. Organic & biomolecular chemistry, 2012, Sep-21, Volume: 10, Issue:35 Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Biological Products; Cell Line; Cell Survival; Coumarins; Cytotoxins; Disulfides; Fibroblasts; Fluorescent Dyes; Fungi; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Mice; Microscopy, Fluorescence; Mycoses; Porifera; Tyrosine	2012
Indole-derived psammaplin A analogues as epigenetic modulators with multiple inhibitory activities. Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Proliferation; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Epigenomics; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Immunoprecipitation; Indoles; Leukemia, Myeloid, Acute; MCF-7 Cells; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Oximes; Protein Conformation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Tyrosine; U937 Cells	2012
Pharmacokinetics and tissue distribution of psammaplin A, a novel anticancer agent, in mice. Archives of pharmacal research, 2012, Volume: 35, Issue:10 Topics: Animals; Antineoplastic Agents; Disulfides; DNA Modification Methylases; Drug Stability; Half-Life; Histone Deacetylase Inhibitors; Histone Deacetylases; Injections, Intravenous; Male; Mice; Mice, Inbred ICR; Tissue Distribution; Tyrosine	2012
Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A. ChemMedChem, 2013, Volume: 8, Issue:1 Topics: Amides; Disulfides; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Docking Simulation; Picolinic Acids; Protein Isoforms; Tyrosine	2013
Psammaplin A inhibits hepatitis C virus NS3 helicase. Journal of natural medicines, 2013, Volume: 67, Issue:4 Topics: Adenosine Triphosphatases; Animals; Antiviral Agents; Cell Line; Disulfides; Hepacivirus; RNA; RNA Helicases; Tyrosine; Viral Nonstructural Proteins; Virus Replication	2013
Delayed toxicity of two chitinolytic enzyme inhibitors (psammaplin a and pentoxifylline) against eastern subterranean termites (Isoptera: Rhinotermitidae). Journal of economic entomology, 2013, Volume: 106, Issue:4 Topics: Animals; Disulfides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoptera; Lethal Dose 50; Pentoxifylline; Time Factors; Tyrosine	2013
Psammaplin a improves development and quality of somatic cell nuclear transfer mouse embryos. Cellular reprogramming, 2014, Volume: 16, Issue:5 Topics: Animals; Disulfides; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Histone Deacetylase Inhibitors; Mice; Nuclear Transfer Techniques; Tyrosine; Valproic Acid	2014
Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochimica et biophysica acta, 2015, Volume: 1850, Issue:2 Topics: Acetylation; Animals; Antibiotics, Antineoplastic; Autophagy; Breast Neoplasms; Cell Division; Cell Line, Tumor; Disulfides; Doxorubicin; Drug Resistance, Neoplasm; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Membrane Proteins; Mice; Mice, Nude; Neoplasm Transplantation; Sirtuin 1; Tumor Suppressor Protein p53; Tyrosine; Xenograft Model Antitumor Assays	2015
Efficient synthesis and biological activity of Psammaplin A and its analogues as antitumor agents. European journal of medicinal chemistry, 2015, Volume: 96 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Disulfides; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured; Tyrosine	2015
Determination and validation of psammaplin A and its derivatives in rat plasma by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Sep-01, Volume: 1000 Topics: Animals; Chromatography, Liquid; Disulfides; Drug Stability; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tyrosine	2015
Morphokinetics of cloned mouse embryos treated with epigenetic drugs and blastocyst prediction. Reproduction (Cambridge, England), 2016, Volume: 151, Issue:3 Topics: Animals; Ascorbic Acid; Cloning, Organism; Disulfides; Embryo, Mammalian; Embryonic Development; Embryonic Stem Cells; Epigenesis, Genetic; Mice, Inbred C57BL; Nuclear Transfer Techniques; Tyrosine	2016
In vitro and in vivo anti-Vibrio vulnificus activity of psammaplin A, a natural marine compound. Molecular medicine reports, 2016, Volume: 14, Issue:3 Topics: Animals; Anti-Bacterial Agents; Aquatic Organisms; Biological Products; Cell Line; Disease Models, Animal; Disulfides; Epithelial Cells; Female; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Tyrosine; Vibrio Infections; Vibrio vulnificus	2016
Synthesis, biological evaluation and molecular modeling studies of psammaplin A and its analogs as potent histone deacetylases inhibitors and cytotoxic agents. Bioorganic & medicinal chemistry letters, 2016, 09-01, Volume: 26, Issue:17 Topics: Cytotoxins; Disulfides; Enzyme Activation; Histone Deacetylase Inhibitors; Humans; Molecular Docking Simulation; Tyrosine	2016
Triggering of Suicidal Erythrocyte Death by Psammaplin A. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:3 Topics: Aniline Compounds; Annexin A5; Biological Products; Calcium; Cells, Cultured; Ceramides; Disulfides; Eryptosis; Erythrocytes; Fluoresceins; Fluorescent Dyes; Hemolysis; Humans; Oxidative Stress; Phosphatidylserines; Reactive Oxygen Species; Spectrometry, Fluorescence; Tyrosine; Xanthenes	2016
Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure. Marine drugs, 2016, Aug-16, Volume: 14, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Aquatic Organisms; Autophagy; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Disulfides; Humans; Plicamycin; Quinones; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Tumor Suppressor Protein p53; Tyrosine	2016
Camptothecin-psammaplin A hybrids as topoisomerase I and HDAC dual-action inhibitors. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Proliferation; Cells, Cultured; Disulfides; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tyrosine	2018
Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products. Viruses, 2018, 06-27, Volume: 10, Issue:7 Topics: Anti-HIV Agents; Aquatic Organisms; Biological Products; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Disulfides; Drug Discovery; High-Throughput Screening Assays; HIV Infections; HIV-1; Humans; Panobinostat; Phorbol Esters; Proviruses; Tyrosine; Virus Activation; Virus Latency	2018
Biochemical and Anti-Triple Negative Metastatic Breast Tumor Cell Properties of Psammaplins. Marine drugs, 2018, Nov-10, Volume: 16, Issue:11 Topics: Animals; Antineoplastic Agents; Apoptosis; Aquatic Organisms; Cell Line, Tumor; Cell Proliferation; Culture Techniques; Disulfides; Drug Discovery; Drug Screening Assays, Antitumor; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Porifera; Spheroids, Cellular; Triple Negative Breast Neoplasms; Tyrosine	2018
Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? Bioorganic & medicinal chemistry letters, 2019, 02-15, Volume: 29, Issue:4 Topics: Anti-Bacterial Agents; Biofilms; Disulfides; Gram-Negative Bacteria; Microbial Sensitivity Tests; Structure-Activity Relationship; Triazoles; Tyrosine	2019
Synthesis and Preliminary Biological Evaluation of Two Fluoroolefin Analogs of Largazole Inspired by the Structural Similarity of the Side Chain Unit in Psammaplin A. Marine drugs, 2019, Jun-03, Volume: 17, Issue:6 Topics: Alkenes; Aquatic Organisms; Cyanobacteria; Depsipeptides; Disulfides; Enzyme Activation; Histone Deacetylase Inhibitors; Histone Deacetylases; Thiazoles; Tyrosine	2019
Inhibition of the Quorum Sensing System, Elastase Production and Biofilm Formation in Molecules (Basel, Switzerland), 2022, Mar-06, Volume: 27, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Disulfides; Pancreatic Elastase; Pseudomonas aeruginosa; Quorum Sensing; Tyrosine; Virulence Factors	2022