tyrosine has been researched along with peroxynitric acid in 309 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 189 (61.17) | 18.2507 |
| 2000's | 120 (38.83) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beckman, JS; Chen, J; Ischiropoulos, H; Martin, JC; Smith, CD; Tsai, M; Zhu, L | 1 |
| Beckman, JS; Carson, M; Chen, J; Ischiropoulos, H; Smith, CD; van der Woerd, M | 1 |
| Ischiropoulos, H; Salzman, AL; Szabó, C | 1 |
| al-Mehdi, AB; Fisher, AB; Ischiropoulos, H | 1 |
| Duran, D; Horwitz, J; Ischiropoulos, H | 1 |
| Cross, CE; Eiserich, JP; Halliwell, B; Van der Vliet, A | 1 |
| al-Mehdi, AB; Ischiropoulos, H | 1 |
| Van der Walt, BJ; Van Zyl, JM | 1 |
| Beckman, JS | 2 |
| Barnard, M; Turrens, JF; Watts, BP | 1 |
| Cueto, R; Jin, X; Koppenol, WH; Ngu-Schwemlein, M; Pryor, WA; Squadrito, GL; Uppu, PL; Uppu, RM | 1 |
| Beckman, JS; Galliani, C; Haddad, IY; Hu, P; Matalon, S; Pataki, G | 1 |
| Cross, CE; Halliwell, B; Kaur, H; O'Neill, CA; van der Vliet, A | 1 |
| Guérin, MC; Salman-Tabcheh, S; Torreilles, J | 1 |
| Halliwell, B; Tritschler, H; Whiteman, M | 1 |
| Ghio, AJ; Oury, TD; Piantadosi, CA; Tatro, L | 1 |
| Bigelow, DJ; Ferrington, DA; Hühmer, AF; Schöneich, C; Viner, RI | 1 |
| Chock, PB; Kong, SK; Stadtman, ER; Yim, MB | 1 |
| Duran, D; Gow, AJ; Ischiropoulos, H; Malcolm, S | 1 |
| Hurst, JK; Jiang, Q; Lymar, SV | 1 |
| Buttery, LD; Chester, AH; Evans, TJ; Parums, DV; Polak, JM; Springall, DR; Standfield, EN; Yacoub, MH | 1 |
| Halliwell, B; Kaur, H; Whiteman, M | 1 |
| Berlett, BS; Chock, PB; Friguet, B; Stadtman, ER; Yim, MB | 1 |
| Beckman, JS; Rosen, H; Sampson, JB | 1 |
| Brockman, DE; Eis, AL; Greer, I; Lyall, F; Myatt, L; Rosenfield, RB | 1 |
| Duran, D; Gow, A; Ischiropoulos, H; Thom, SR | 1 |
| Chou, SM; Komai, K; Wang, HS | 1 |
| Althaus, JS; Fici, GJ; Hall, ED; Von Voigtlander, PF | 1 |
| Kawka, DW; Mumford, RA; Riehl, TE; Scott, S; Singer, II; Stenson, WF; Weidner, JR | 1 |
| Bhattacharya, M; Fiala, ES; Li, H; Sodum, RS | 1 |
| Beckman, JS; Crow, JP; Kerby, JD; MacMillan-Crow, LA; Thompson, JA | 1 |
| Kooy, NW; Lewis, SJ | 2 |
| Halliwell, B; Whiteman, M | 4 |
| Dallner, G; Ernster, L; Forsmark-Andrée, P; Persson, B; Radi, R | 1 |
| Augusto, O; Capurro, Mde L; de Bianchi, AG; Giorgio, S; Linares, E | 1 |
| Baldwin, J; Francescutti, D; Lee, L; Mutus, B | 1 |
| Mondoro, TH; Shafer, BC; Vostal, JG | 1 |
| Aruoma, OI; England, TG; Halliwell, B; Whiteman, M | 1 |
| Augusto, O; Giorgio, S; Linares, E | 1 |
| Beckman, JS; Perry, G; Richey Harris, PL; Sayre, LM; Smith, MA | 1 |
| Ames, BN; Blount, BC; Christen, S; Lee, HH; Shigenaga, MK; Shigeno, ET; Yip, H | 1 |
| Fukuyama, N; Hida, M; Ichimori, K; Ishida, H; Nakazawa, H; Takebayashi, Y | 1 |
| Hemmens, B; Leopold, E; Mayer, B; Pfeiffer, S; Schmidt, K; Werner, ER | 1 |
| Halliwell, B; Pannala, AS; Rice-Evans, CA; Singh, S | 1 |
| Abdalla, DS; Moriel, P | 1 |
| Rabinovitch, A; Suarez-Pinzon, WL; Szabó, C | 1 |
| Barnes, PJ; Giaid, A; Saleh, D | 1 |
| Chandler, RT; Crow, JP; Parks, DA; Skinner, HB; Skinner, KA; Thompson, JA | 1 |
| Beckman, JS; Kelly, DR; Kooy, NW; Lewis, SJ; Royall, JA; Ye, YZ | 1 |
| Curtis, JF; Eling, TE; Gierse, JK; Gunther, MR; Hsi, LC; Marnett, LJ; Mason, RP | 1 |
| Hinton, DR; Hofman, FM; Incardonna, F; van der Veen, RC | 1 |
| Blount, BC; Duncan, MW; Smythe, GA; Yi, D | 1 |
| Minetti, M; Pietraforte, D | 1 |
| Halliwell, B | 1 |
| Martin, C; Ullrich, V; Zou, M | 1 |
| Ischiropoulos, H; Thom, SR; Xu, YA | 1 |
| Fu, W; Furukawa, K; Goodman, Y; Luo, H; Mattson, MP | 1 |
| Beckman, JS; Crow, JP; Sampson, JB; Thompson, JA; Zhuang, Y | 1 |
| Barnes, S; Beckman, JS; Crow, JP; Kirk, M; Strong, M; Ye, YZ | 1 |
| Caputi, AP; Cuzzocrea, S; O'Connor, M; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Bruckdorfer, KR; Jacobs, M; Khan, J | 1 |
| Bruckdorfer, KR; Jacobs, M; Khan, J; Naseem, KM | 1 |
| Cuzzocrea, S; Gilad, E; Hake, P; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Di Stasi, AM; Mallozzi, C; Minetti, M | 1 |
| Cross, AH; Manning, PT; Misko, TP; Stern, MK | 1 |
| Halliwell, B; Rehman, A; Whiteman, M | 1 |
| Bruce-Keller, AJ; Germeyer, A; Holtsberg, FW; Hutchins, JB; Keller, JN; Kindy, MS; Mattson, MP; St Clair, DK; Steiner, SM; Yen, HC | 1 |
| Ashida, K; Ataka, M; Kamisaki, Y; Kishimoto, Y; Nakamoto, K; Wada, K; Yamada, Y | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Henderson, CE; Manuel, SM; Radi, R; Spear, N | 1 |
| Fukuyama, N; Hoshiai, K; Ishida, H; Nakazawa, H; Shinohara, Y; Takizawa, S | 1 |
| Crow, JP; MacMillan-Crow, LA; Thompson, JA | 1 |
| Hansen, P; Heinecke, JW; Holloszy, JO; Leeuwenburgh, C; Shaish, A | 1 |
| Berlett, BS; Levine, RL; Stadtman, ER | 1 |
| Akiba, Y; Fujimori, H; Higuchi, H; Hirokawa, M; Hokari, R; Ishii, H; Kimura, H; Kurose, I; Miura, S; Serizawa, H; Shigematsu, T; Tsuzuki, Y | 1 |
| Halliwell, B; Pannala, AS; Razaq, R; Rice-Evans, CA; Singh, S | 1 |
| Ballard, PL; Ballard, RA; Banks, BA; Ischiropoulos, H; McClelland, M | 1 |
| Di Stasi, AM; Mallozzi, C; Minetti, M; Pietraforte, D | 1 |
| Arai, Y; Cheng, X; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, Ji; Shimokawa, H; Takeshita, A | 1 |
| Arnaud, S; Ben-Ari, Y; Cachin, N; Charriaut-Marlangue, C; Coeroli, L; Plotkine, D; Plotkine, M; Renolleau, S | 1 |
| Fujimura, T; Murayama, K; Taka, H; Yamakura, F | 1 |
| Hinson, JA; Mayeux, PR; Pike, SL; Pumford, NR | 1 |
| Adam, JM; Bradley, NJ; Bruckdorfer, KR; Ettelaie, C; James, NJ; Naseem, KM | 1 |
| Choe, N; Hemenway, DR; Kagan, E; Matalon, S; Tanaka, S; Zhu, S | 1 |
| Koppenol, WH | 1 |
| Caputi, AP; Cuzzocrea, S; Longo, G; Villari, D; Zingarelli, B | 1 |
| Beckman, JS; Crow, JP; Sopper, MM; Strong, MJ; Strong, WL | 1 |
| Baier-Bitterlich, G; Fuchs, D; Wede, I; Widner, B; Wirleitner, B | 1 |
| Cross, AH; Keeling, RM; Manning, PT; Misko, TP; Schmidt, RE | 1 |
| Beckman, JS; Rosen, H; Sampson, JB; Ye, Y | 1 |
| Ducastel, B; Guittet, O; Henry, Y; Lemaire, G; Lepoivre, M; Rubin, H; Salem, JS | 1 |
| Gon, Y; Hashimoto, N; Kikuchi, H; Nishiyama, A; Nozaki, K; Sono, H; Takagi, Y; Todaka, T; Yodoi, J | 1 |
| Allix, M; Boulu, RR; Charriaut-Marlangue, C; Mésenge, C; Plotkine, M; Verrecchia, C | 1 |
| Quinn, MT; Rohn, TT | 1 |
| Fakhrzadeh, L; Gardner, CR; Heck, DE; Laskin, DL; Laskin, JD; Weinberger, B | 1 |
| Caputi, AP; Cuzzocrea, S; Zingarelli, B | 2 |
| Mayer, B; Pfeiffer, S | 1 |
| Cuzzocrea, S; Marmer, D; Salzman, AL; Scott, GS; Szabó, C; Virág, L | 1 |
| Fukuyama, N; Genka, C; Ishida, H; Nakazawa, H; Su, Z; Todorov, R | 1 |
| Boggs, SE; Hellberg, CB; Lapetina, EG | 1 |
| Halliwell, B; Jenner, P; Marshall, KA; Reist, M | 1 |
| Bryan, TW; Grisham, MB; Jinkins, PA; Jones, KL; Markewitz, BA; Milligan, SA; Owens, MW; Robbins, RA; Simpson, KL | 1 |
| Ahmed, F; Anthony, GM; Bank, N; Fabry, ME; Kiroycheva, M; Nagel, RL; Singhal, PC | 1 |
| Daiber, A; Mehl, M; Ullrich, V | 1 |
| Cuzzocrea, S; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Haramaki, N; Ikeda, H; Imaizumi, T; Mori, E | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E | 1 |
| Fisher, D; Ischiropoulos, H; Ohnishi, ST; Thom, SR; Xu, YA | 1 |
| Jutila, KL; Nelson, LK; Quinn, MT; Rohn, TT; Sipes, KM; Swain, SD | 1 |
| Jakeman, LB; Scott, GS; Stokes, BT; Szabó, C | 1 |
| Chen, JS; Chen, LW; Chen, SC; Hsu, CM; Wang, JS | 1 |
| Cavallini, D; Fontana, M; Macone, A; Pecci, L | 1 |
| Davidge, ST; Roggensack, AM; Zhang, Y | 1 |
| Barbeito, L; Beckman, JS; Estévez, AG; Manuel, SM; Radi, R; Spear, N | 1 |
| Carthy, CM; Glysing-Jensen, T; Granville, DJ; Koglin, J; McManus, BM; Mudgett, JS; Russell, ME | 1 |
| Minetti, M; Pietraforte, D; Scorza, G | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S | 1 |
| Akizuki, E; Liang, J; Matsuda, T; Matsumura, F; Mori, K; Ogawa, M; Ohshiro, H; Okabe, K; Yamada, S; Yamaguchi, Y | 1 |
| Goss, SP; Hogg, N; Kalyanaraman, B | 1 |
| Baker, CS; Creminon, C; Evans, TJ; Hall, RJ; Maclouf, J; Polak, JM; Pomerance, A; Yacoub, MH | 1 |
| Brito, C; Cayota, AM; Dighiero, G; Gualco, G; Naviliat, M; Radi, R; Tiscornia, AC; Vuillier, F | 1 |
| Balazy, M; Jiang, H | 1 |
| Arteel, GE; Bradford, BU; Kadiiska, MB; Mason, RP; Raleigh, JA; Rusyn, I; Thurman, RG | 1 |
| Stanbro, WD | 1 |
| Boven, LA; Gomes, L; Gray, F; Hery, C; Nottet, HS; Portegies, P; Tardieu, M; Verhoef, J | 1 |
| Fujii, T; Nakaki, T | 1 |
| Calingasan, NY; Gibson, GE; Kristal, BS; Lindsay, JG; Park, LC; Sheu, KF; Zhang, H | 1 |
| Jendral, M; Ullrich, V; Zou, M | 1 |
| Briviba, K; Klotz, LO; Schieke, SM; Sies, H | 1 |
| Aeschbach, R; Aruoma, OI; Banni, S; Bianchi, ML; Corongiu, FP; Deiana, M; Dessi, MA; Halliwell, B; Kaur, H; Spencer, JP | 1 |
| Groves, JT | 1 |
| Fung, HL; Maurer, TS; Tabrizi-Fard, MA | 1 |
| Darley-Usmar, VM; Freeman, BA; Jo, H; McAndrew, J; Patel, RP; Sellak, H; White, CR | 1 |
| Halliwell, B; Szabó, C; Whiteman, M | 1 |
| Batinić-Haberle, I; Ferrer-Sueta, G; Fridovich, I; Radi, R; Spasojević, I | 1 |
| MacMillan-Crow, LA; Thompson, JA | 1 |
| Ullrich, V; Yesilkaya, A; Zou, M | 1 |
| Blazar, BR; Haddad, IY; Ingbar, DH; Milla, CE; Panoskaltsis-Mortari, A; Yang, S | 1 |
| Bigelow, DJ; Ferrington, DA; Schöneich, C; Viner, RI; Williams, TD | 1 |
| Celan, I; Chazotte, L; Mower, HF; Ohshima, H; Pignatelli, B | 1 |
| Davis, AR; Nelson, LK; Quinn, MT; Rohn, TT | 1 |
| Kerry, N; Rice-Evans, C | 1 |
| Berlett, BS; Chock, PB; Levine, RL; Stadtman, ER; Tien, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E; Micali, A; Zingarelli, B | 1 |
| Amirmansour, C; Bogle, RG; Vallance, P | 1 |
| Maeda, S; Saeki, M | 1 |
| Eliasson, MJ; Ferrante, RJ; Huang, Z; Molliver, ME; Moskowitz, MA; Sasamata, M; Snyder, SH | 1 |
| Kanadia, RN; Kuo, WN; Shanbhag, VP | 1 |
| Di Stasi, AM; Macchia, G; Mallozzi, C; Minetti, M; Petrucci, TC | 1 |
| Grisham, MB; Koyama, S; Robbins, RA; Sato, E; Simpson, KL | 3 |
| Ali, SF; Crow, JP; Imam, SZ; Islam, F; Newport, GD; Slikker, W | 1 |
| Lehnig, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Zingarelli, B | 1 |
| Brown, LA; Fortenberry, JD; Owens, ML; Raghuram, N | 1 |
| Brain, SD; Evans, P; Greenacre, SA; Halliwell, B | 1 |
| Kastenbauer, S; Koedel, U; Pfister, HW | 1 |
| Guittet, O; Lepoivre, M; Roy, B | 1 |
| Beckman, JS; Crow, JP; MacMillan-Crow, LA; Takakura, K | 1 |
| Bauer, JA; Coyle, CM; Jing, L; Mihm, MJ | 1 |
| Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Mazzon, E | 1 |
| Perry, G; Sayre, LM; Smith, MA | 1 |
| Baker, C; Evans, TW; Gutteridge, JM; Lamb, NJ; Quinlan, GJ | 1 |
| Doi, U; Kato, Y; Niwa, T; Osawa, T | 2 |
| Higuchi, H; Hokari, R; Ishii, H; Kimura, H; Miura, S; Mizumori, M; Mori, M; Sakaguchi, AA; Suzuki, H; Takeuchi, T; Yoshida, H | 1 |
| Michaelis, ML; Zaidi, A | 1 |
| Beckman, JS; Darley-Usmar, VM; Go, YM; Jo, H; Maland, MC; Park, H; Patel, RP | 1 |
| Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Di Rosa, M; Ialenti, A; Mazzon, E; Rombolà, L; Sautebin, L; Thiemermann, C | 1 |
| Kanadia, RN; Kuo, WN; Morgan, R; Shanbhag, VP | 1 |
| Cheng, XS; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, J; Shimokawa, H; Takeshita, A | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E; Reiter, RJ; Tan, DX | 1 |
| Daikhin, E; Ischiropoulos, H; Raman, CS; Souza, JM; Yudkoff, M | 1 |
| Hasegawa, K; Ochiai-Kanai, R; Sawada, T; Takeuchi, Y; Yoshioka, H | 1 |
| Caputi, AP; Cuzzocrea, S; El-Sokkary, GH; Hassanein, AF; Reiter, RJ; Tan, DX | 1 |
| Heinecke, JW; Jackson-Lewis, V; Pennathur, S; Przedborski, S | 1 |
| Aretha, CW; Geddes, TJ; Kuhn, DM | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E | 1 |
| Arteel, GE; Sies, H | 1 |
| Cheung, R; Mutus, B; Tannous, M; Vignini, A | 1 |
| Alber, S; Boyle, P; Dickinson, E; Ford, H; Nadler, E; Tuncer, R; Watkins, S | 1 |
| Kanadia, RN; Kuo, WN; Shanbhag, VP; Toro, R | 1 |
| Halliwell, B; Whiteman, M; Zhao, K | 1 |
| Beckman, JS; Darley-Usmar, V; Digerness, SB; Harris, KD; Kirklin, JW; Urthaler, F; Viera, L | 1 |
| Czapski, G; Goldstein, S; Lind, J; Merényi, G | 1 |
| Bauer, JA; Holycross, BJ; Wattanapitayakul, SK; Weinstein, DM | 1 |
| Fukuyama, N; Hirabayashi, H; Nakazawa, H; Shinohara, Y; Takizawa, S | 1 |
| Mayer, B; Pfeiffer, S; Schmidt, K | 1 |
| Bernstein, C; Bernstein, H; Hoglen, N; Payne, CM; Washo-Stultz, D | 1 |
| Ault, SG; Hinson, JA; Michael, SL; Pumford, NR | 1 |
| Ikota, N; Matsushima, Y; Nakagawa, H; Ozawa, T; Sumiki, E; Takusagawa, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Filipe, HM; Mazzon, E; McDonald, MC; Santagati, S; Thiemermann, C | 1 |
| Daiber, A; Peterson, JA; Shoun, H; Ullrich, V; Zou, MH | 1 |
| Balazy, M; Boulos, C; Jiang, H | 1 |
| Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV; Zborek, A | 1 |
| Briviba, K; Buchczyk, DP; Hartl, FU; Sies, H | 1 |
| Brockman, D; Eis, A; Kossenjans, W; Myatt, L; Sahay, R | 1 |
| Hirouchi, M; Itoh, Y; Oka, M; Ukai, Y | 1 |
| Aoyama, K; Fujikawa, Y; Hayase, N; Kobayashi, S; Matsubara, K; Nagahiro, Y; Shimizu, K; Shiono, H; Umegae, N | 1 |
| Decottignies, P; Guittet, O; Henry, Y; Laprévote, O; Le Maréchal, P; Lepoivre, M; Serani, L | 1 |
| Knight, KR; Liu, T; Tracey, DJ | 1 |
| Celan, I; Friesen, MD; Masuda, M; Mower, HF; Nishino, H; Ohshima, H; Pignatelli, B | 1 |
| Augusto, O; Bonini, MG; Santos, CX | 1 |
| Choi, I; Finkel, B; Foust, RF; Gole, MD; Hertkorn, C; Ischiropoulos, H; Lanken, PN; Malcolm, S; Souza, JM | 1 |
| Basiouny, KF; Crow, JP; Matalon, S; Zhu, S | 1 |
| Dodd, SM; Nott, CA; Thuraisingham, RC; Yaqoob, MM | 1 |
| Bradley, NJ; Bruckdorfer, KR; Jacobs, M; Khan, J; Low, SY; Naseem, KM; Sabetkar, M | 1 |
| Cross, AH; Keeling, RM; Misko, TP; Salvemini, D; San, M; Stern, MK | 1 |
| Mayeux, PR; Walker, LM; Zhang, C | 1 |
| Ben-Ari, Y; Benjelloun, N; Charriaut-Marlangue, C; Ducrocq, S; Plotkine, M | 1 |
| Calhoun, W; Comhair, SA; Dweik, RA; Eissa, NT; Erzurum, SC; Guo, FH; Thomassen, MJ; Zheng, S | 1 |
| Carbone, V; Marino, G; Minetti, M; Pietraforte, D; Salzano, AM; Scorza, G | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Macarthur, H; Mazzon, E; Micali, A; Misko, TP; Salvemini, D | 1 |
| Greendorfer, JS; MacMillan-Crow, LA; Thompson, JA; Vickers, SM | 1 |
| Alvarez, B; Boveris, A; Cadenas, E; Carreras, MC; Poderoso, JJ; Radi, R; Riobó, N; Schöpfer, F | 1 |
| Bauer, JA; Mihm, MJ; Weinstein, DM | 1 |
| Haginaka, J; Kagota, S; Kunitomo, M; Yamaguchi, Y | 1 |
| Anthony, GM; Bank, N; Kiroycheva, M; Singhal, PC; Southan, GJ; Szabo, C | 1 |
| Akaike, T; Kubota, T; Kuwahara, H; Maeda, H; Miyamoto, Y; Okamoto, S; Sawa, T | 1 |
| Akaike, T; Maeda, H; Sawa, T | 1 |
| Beckman, JS; Reiter, CD; Teng, RJ | 1 |
| Arteel, GE; Schroeder, P; Sies, H | 1 |
| Chen, SS; Jou, LS; Kang, BH; Wang, HW; Weng, PK | 1 |
| Vinten-Johansen, J | 1 |
| Bolay, H; Dalkara, T; Gürsoy-Ozdemir, Y; Saribaş, O | 1 |
| Ikeno, S; Kigawa, J; Nagata, N; Takahashi, H; Terakawa, N; Yoshida, S | 1 |
| Traber, DL | 1 |
| Kamisaki, Y; Maeda, S; Saeki, M | 1 |
| Hadeli, K; Hoyt, JC; Nelson, D; Robbins, RA; Sato, E | 1 |
| Fukuyama, N; Hayashi, Y; Matsuda, H; Nakazawa, H; Nishimura, M; Sawa, Y; Tojo, SJ | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E; Serraino, I | 1 |
| Chen, KJ; Chu, YR; Lin, JK; Lin-Shiau, SY; Liu, GY | 1 |
| Ackerman, A; Kalyanaraman, B; Pritchard, KA | 1 |
| Brodsky, S; Ebin, Z; Goligorsky, MS; Jin, H; Li, H; Zhang, X | 1 |
| Hong, HJ; Loh, SH; Yen, MH | 1 |
| Butler, AR; Ridd, JH; Rutherford, TJ; Short, DM | 1 |
| Carreras, MC; Cherñavsky, A; Gatto, EM; Poderoso, JJ; Riobó, NA; Rubio, A; Satz, ML | 1 |
| Ling, X; Liu, D; Liu, J; Wen, J | 1 |
| Alvarez, S; Arnaiz, SL; Boveris, A; Carreras, MC; Poderoso, JJ; Schöpfer, F; Valdez, LB | 1 |
| Bartosz, G; Grzelak, A; Mateja, A; Soszyński, M; Stepień, K; Wilczok, A; Wilczok, T; Zajdel, A | 1 |
| Akaike, T; Akizuki, E; Fujii, S; Maeda, H; Ogawa, M; Okamoto, S; Yamaguchi, Y | 1 |
| Daiber, A; Jung, C; Schmidt, P; Schöneich, C; Ullrich, V | 1 |
| Adhami, A; Bamberg, T; Chumley, P; Crow, J; Eiserich, JP; Estevez, A; Freeman, BA; Lang, JD | 1 |
| Holbrook, NJ; Klotz, LO; Schieke, SM; Sies, H | 1 |
| Deby-Dupont, G; Hans, P; Kohnen, S; Lamy, M; Mathy-Hartert, M; Mouithys-Mickalad, A | 1 |
| Calabro, G; Caputi, AP; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; van De LOO, FA | 1 |
| Kato, Y; Osawa, T; Tsuda, T | 1 |
| Daiber, A; Herold, S; Namgaladze, D; Peterson, JA; Schöneich, C; Ullrich, V | 1 |
| Jasin, HE; Uesugi, M; Yoshida, K | 1 |
| Asagiri, K; Habara, T; Kamada, Y; Kudo, T; Nakatsuka, M; Noguchi, S; Takata, M | 1 |
| Halliwell, B; Ketsawatsakul, U; Whiteman, M | 1 |
| Maguluri, S; Rao, NA; Read, RW; Zhang, J | 1 |
| Bachschmid, M; Erusalimsky, JD; Gygi, D; Kilo, J; Labugger, R; Lüscher, TF; Malinski, T; Palacios-Callender, M; Powell, JM; Quaschning, T; Skepper, JN; Ullrich, V; van der Loo, B | 1 |
| Althaus, JS; Carroll, RT; Fountain, ST; Galatsis, P; Hall, ED; Schmidt, KR; Tseng, MT | 1 |
| Hodges, GR; Ingold, KU; Marwaha, J; Paul, T | 1 |
| Camhi, SL; Koyama, S; Nelson, DK; Robbins, RA; Sato, E | 1 |
| Aston, K; Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D | 1 |
| Ali, SF; Cadet, JL; Imam, SZ; Islam, F; Itzhak, Y; Newport, GD; Slikker, W | 1 |
| Ross, GF; Szabó, C; Trapnell, BC; Whitsett, JA; Zsengellér, ZK | 1 |
| Alvarez, MN; Cayota, A; Naviliat, M; Peluffo, G; Radi, R | 1 |
| Ferrini, M; González-Cadavid, NF; Magee, TR; Rajfer, J; Vernet, D | 1 |
| Ikota, N; Matsushima, Y; Nakagawa, H; Ozawa, T; Sumiki, E | 1 |
| Bauer, JA; Coyle, CM; Mihm, MJ; Schanbacher, BL; Weinstein, DM | 1 |
| Blanchard, EB; Cudic, M; Ducrocq, C; Servy, C | 1 |
| Liu, L; Ragan, V; Seidel, ER | 1 |
| Feustel, PJ; Kimelberg, HK; Mongin, AA; Osuka, K; Tranmer, BI | 1 |
| Blanchard, B; Ducrocq, C; Servy, C | 1 |
| Conklin, JL; Kooy, N; Murray, JA; Uc, A | 1 |
| Douglass, LW; Ledbetter, TK; Paape, MJ | 1 |
| Ferdinandy, P; Schulz, R | 1 |
| Comhair, SA; Erzurum, SC; Hazen, SL; Kavuru, MS; Klein, DF; Lipscomb, MF; MacPherson, JC; Samoszuk, MK | 1 |
| Camhi, SL; Hoyt, JC; Nelson, DK; Robbins, RA; Robinson, VK; Sato, E | 1 |
| Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Akaike, T; Hayashida, K; Maeda, H; Okamoto, T; Okuyama, A; Wu, J | 1 |
| Lai, PS; Lin, KT; Linask, KK; Liu, X; Nagele, RG; Sun, FF; Wang, C; Wong, PY; Yin, K; Yue, G | 1 |
| Archard, LC; Bevan, AL; Li, Y; Zhang, H | 1 |
| Arimura, K; Eto, K; Fukuyama, N; Miyamoto, K; Moriguchi, S; Murao, K; Nakanishi, H; Osame, M; Wakamiya, J | 1 |
| Berrih-Aknin, S; Gaudry-Talarmain, YM; Moulian, N; Serraf, A; Truffault, F | 1 |
| Jiao, K; Mandapati, S; Skipper, PL; Tannenbaum, SR; Wishnok, JS | 1 |
| Feix, J; Hogg, N; Joseph, J; Kalyanaraman, B; Zhang, H | 1 |
| Lass, A; Mayer, B; Pfeiffer, S; Schmidt, K | 1 |
| Bai, P; Bakondi, E; Gergely, P; Gyüre, L; Haskó, G; Hunyadi, J; Szabó, C; Szabó, E; Virág, L | 1 |
| Grisham, MB; Kilinc, A; Kilinc, K; Wolf, RE | 1 |
| Buchczyk, DP; Klotz, LO; Sadik, CD; Schewe, T; Schroeder, P; Sies, H | 1 |
| Ali, SF; Cadet, JL; el-Yazal, J; Imam, SZ; Itzhak, Y; Newport, GD; Slikker, W | 1 |
| Csonka, C; Csont, T; Ferdinandy, P; Onody, A | 1 |
| Gupta, MP; Hart, CM; Knepler, JL; Ober, MD; Patterson, C; Pavalko, F; Taher, LN | 1 |
| Bekker, JM; Black, SM; Fineman, JR; McMullan, DM; Wedgwood, S | 1 |
| Ali, SF; Imam, SZ; Mayeux, PR; Muldrew, KL; Walker, LM; York, JL | 1 |
| Fukuyama, N; Hayashi, Y; Matsuda, H; Nakazawa, H; Ohtake, S; Sawa, Y | 1 |
| Ceriello, A; Giugliano, D; Marfella, R; Nappo, F; Quagliaro, L | 1 |
| Hayes, EL; Kanterewicz, BI; Klann, E; Knapp, LT | 1 |
| Abe, K; Hayashi, T; Manabe, Y; Murakami, T; Shoji, M; Wang, JM; Warita, H | 1 |
| Ali, SF; Imam, SZ | 1 |
| Blazar, BR; Cornfield, DN; Haddad, IY; Milla, C; Panoskaltsis-Mortari, A; Porter, VA; Yang, S | 1 |
| Baliga, RS; Bauer, JA; Carnes, CA; Chung, MK; Hamlin, RL; Kanderian, A; McCarthy, PM; Nakayama, H; Nakayama, T; Pavia, S; Piao, S; Van Wagoner, DR | 1 |
| Coffey, MJ; Peters-Golden, M; Phare, SM | 1 |
| Ducrocq, C; Gaudry-Talarmain, YM; Guermonprez, L | 1 |
| Bai, P; Bakondi, E; Gergely, P; Szabó, C; Szabó, E; Virág, L | 1 |
| Echizenya, M; Hiai, H; Imamura, M; Kondo, S; Onodera, H; Ozeki, M; Tachibana, T; Toyokuni, S; Tsuruyama, T | 1 |
| Naseem, KM; Riba, R; Troxler, M | 1 |
| Phipps, J; Sadeghipour, M; Terreux, R | 1 |
| Kirsch, M; Lehnig, M | 1 |
14 review(s) available for tyrosine and peroxynitric acid
| Article | Year |
|---|---|
Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury.
Topics: Animals; Brain; Brain Injuries; Humans; Hydroxyl Radical; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides; Tyrosine | 1994 |
Peroxynitrite-dependent tyrosine nitration catalyzed by superoxide dismutase, myeloperoxidase, and horseradish peroxidase.
Topics: Kinetics; Nitrates; Peroxidase; Substrate Specificity; Superoxide Dismutase; Tyrosine | 1996 |
Possible roles of nitric oxide and peroxynitrite in murine leishmaniasis.
Topics: Animals; Anions; Hemoglobins; Leishmania major; Leishmaniasis; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Oxidants; Reactive Oxygen Species; Superoxides; Tyrosine | 1996 |
Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Death; Cell Survival; Humans; Motor Neurons; Nitrates; Nitric Oxide; Superoxide Dismutase; Tyrosine | 1998 |
Nitration modifying function of proteins, hormones and neurotransmitters.
Topics: Animals; Homeostasis; Hormones; Humans; Neurotransmitter Agents; Nitrates; Nitric Oxide; Oxidants; Oxidative Stress; Proteins; Tetranitromethane; Tyrosine | 1999 |
Peroxynitrite: reactive, invasive and enigmatic.
Topics: Cell Membrane Permeability; Free Radical Scavengers; Mitochondria; Nitrates; Tyrosine | 1999 |
Biological aspects of reactive nitrogen species.
Topics: Animals; Apoptosis; Inflammation; Lipoproteins; Membranes; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Oxidation-Reduction; Signal Transduction; Tyrosine; Vasodilation | 1999 |
Peroxynitrite inactivates prostacyclin synthase by heme-thiolate-catalyzed tyrosine nitration.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Heme; Humans; Intramolecular Oxidoreductases; Nitrates; Nitric Oxide; Sulfhydryl Compounds; Superoxides; Tyrosine; Vascular Resistance | 1999 |
Nitric oxide: a radical molecule in quest of free radicals in proteins.
Topics: Amino Acids; Animals; Arachidonic Acid; Bacterial Proteins; Binding Sites; Free Radicals; Humans; Iron; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Prostaglandin-Endoperoxide Synthases; Proteins; Tyrosine | 1999 |
Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies.
Topics: Animals; Biomarkers; Disease; Humans; Nitrates; Nitric Oxide; Superoxides; Tyrosine | 1999 |
Nitric oxide, peroxynitrite, and lower respiratory tract inflammation.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Eosinophils; Humans; Nitrates; Nitric Oxide; Pneumonia; Tyrosine | 2000 |
Unraveling peroxynitrite formation in biological systems.
Topics: Animals; Carbon Dioxide; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Free Radicals; Humans; Hydroxylation; Immunohistochemistry; Indicators and Reagents; Luminescent Measurements; Nitrates; Oxidants; Oxidative Stress; Phenols; Tyrosine | 2001 |
[Intervention by nitric oxide, NO, and its oxide derivatives particularly in mammals].
Topics: Animals; Humans; Mammals; Nitrates; Nitric Oxide; Protein Processing, Post-Translational; Superoxides; Tyrosine | 2001 |
Methamphetamine-induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts.
Topics: Animals; Antioxidants; Biomarkers; Dopamine; Dopamine Agents; Enzyme Inhibitors; Humans; Indazoles; Methamphetamine; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; PC12 Cells; Rats; Tyrosine | 2001 |
2 trial(s) available for tyrosine and peroxynitric acid
| Article | Year |
|---|---|
Atorvastatin increases ecNOS levels in human platelets of hyperlipidemic subjects.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Blood Platelets; Blood Proteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Enzyme Induction; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Pyrroles; Treatment Outcome; Triglycerides; Tyrosine; Vasodilation | 1999 |
Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation.
Topics: Aged; Animals; Antioxidants; Ascorbic Acid; Atrial Fibrillation; Cardiac Pacing, Artificial; Coronary Artery Bypass; Dogs; Electrophysiology; Female; Heart Atria; Humans; Male; Middle Aged; Multivariate Analysis; Nitrates; Time Factors; Treatment Outcome; Tyrosine | 2001 |
293 other study(ies) available for tyrosine and peroxynitric acid
| Article | Year |
|---|---|
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase.
Topics: Animals; Binding Sites; Cattle; Erythrocytes; Hydrogen-Ion Concentration; Kinetics; Lasers; Nitrates; Nitric Oxide; Protein Conformation; Spectrum Analysis, Raman; Superoxide Dismutase; Tyrosine | 1992 |
Crystal structure of peroxynitrite-modified bovine Cu,Zn superoxide dismutase.
Topics: Animals; Binding Sites; Cattle; Computer Graphics; Crystallography; Glutamates; In Vitro Techniques; Models, Molecular; Nitrates; Nitrites; Protein Structure, Tertiary; Superoxide Dismutase; Tyrosine; X-Ray Diffraction | 1992 |
Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Calcium; Endotoxins; Fluorescent Antibody Technique; Lipopolysaccharides; Male; Nitrates; Nitric Oxide Synthase; Rats; Rats, Wistar; Tyrosine | 1995 |
Reactive species in ischemic rat lung injury: contribution of peroxynitrite.
Topics: Animals; Arginine; Immunohistochemistry; Ischemia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Perfusion; Pressure; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staining and Labeling; Tyrosine | 1995 |
Peroxynitrite-mediated inhibition of DOPA synthesis in PC12 cells.
Topics: Animals; Dihydroxyphenylalanine; Molsidomine; Nitrates; Oxidation-Reduction; PC12 Cells; Rats; Tyrosine | 1995 |
Modification of aromatic amino acids by reactive nitrogen species.
Topics: Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Mannitol; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrogen Oxides; Oxidants; Phenylalanine; Tyrosine | 1995 |
Peroxynitrite-mediated oxidative protein modifications.
Topics: Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Hydrogen-Ion Concentration; Male; Nitrates; Oxidation-Reduction; Oxidative Stress; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Tryptophan; Tyrosine | 1995 |
Apparent hydroxyl radical generation without transition metal catalysis and tyrosine nitration during oxidation of the anti-tubercular drug, isonicotinic acid hydrazide.
Topics: Catalase; Hydroxyl Radical; Isoniazid; Kinetics; Metals; Nitrates; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Thiobarbituric Acid Reactive Substances; Tyrosine | 1994 |
Peroxynitrite-dependent chemiluminescence of amino acids, proteins, and intact cells.
Topics: Amino Acids; Animals; Bicarbonates; Cells, Cultured; Fatty Acids; Hemin; Histones; Hydrogen-Ion Concentration; Luminescent Measurements; Nitrates; Nucleic Acids; Nucleotides; Oxidation-Reduction; Peroxides; Proteins; Serum Albumin, Bovine; Spectrophotometry; tert-Butylhydroperoxide; Trypanosomatina; Tryptophan; Tyrosine | 1995 |
A practical method for preparing peroxynitrite solutions of low ionic strength and free of hydrogen peroxide.
Topics: Azides; Buffers; Drug Contamination; Drug Stability; Free Radicals; Freezing; Hydrogen Peroxide; Hydrogen-Ion Concentration; Nitrates; Osmolar Concentration; Ozone; Sodium Azide; Solutions; Spectrophotometry; Tyrosine | 1995 |
Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.
Topics: Adolescent; Animals; Child; Child, Preschool; Female; Fluorescent Antibody Technique; Humans; Infant; Infant, Newborn; Lung; Male; Microtomy; Nitrates; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome, Newborn; Tyrosine | 1994 |
Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite.
Topics: Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Serum Albumin, Bovine; Thermodynamics; Tyrosine; Uric Acid | 1994 |
Nitration of tyrosyl-residues from extra- and intracellular proteins in human whole blood.
Topics: Blood Proteins; Calcimycin; Humans; Ionophores; Kinetics; Neutrophils; Nitrates; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1995 |
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by oxidized and reduced lipoic acid.
Topics: alpha 1-Antitrypsin; Antioxidants; Free Radical Scavengers; Humans; In Vitro Techniques; Nitrates; Nitric Oxide; Oxidation-Reduction; Reactive Oxygen Species; Thioctic Acid; Tyrosine | 1996 |
Nitration of tyrosine by hydrogen peroxide and nitrite.
Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxylation; Inflammation; Iron; Nitrates; Oxidative Stress; Salicylates; Salicylic Acid; Sodium Nitrite; Tyrosine | 1995 |
Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: a peroxynitrite-mediated process?
Topics: Aging; Animals; Calcium; Calcium-Transporting ATPases; Male; Muscle, Skeletal; Nitrates; Rats; Rats, Inbred F344; Sarcoplasmic Reticulum; Tyrosine | 1996 |
Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide.
Topics: Amino Acid Sequence; CDC2 Protein Kinase; Cell Cycle; Edetic Acid; Ferric Compounds; In Vitro Techniques; Iron Chelating Agents; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Nitrates; Peptide Fragments; Phosphorylation; Signal Transduction; src-Family Kinases; Tyrosine | 1996 |
Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation.
Topics: Animals; Cattle; Endothelium, Vascular; Erythrocytes; Gastrins; Humans; Nitrates; Peptides; Phosphorylation; Plasma; Protein-Tyrosine Kinases; Proteins; Serum Albumin, Bovine; Tyrosine | 1996 |
Mechanism of carbon dioxide-catalyzed oxidation of tyrosine by peroxynitrite.
Topics: Carbon Dioxide; Chromatography, High Pressure Liquid; Kinetics; Nitrates; Oxidation-Reduction; Time Factors; Tyrosine | 1996 |
Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Biomarkers; Blotting, Western; Female; Foam Cells; Humans; In Situ Hybridization; Macrophages; Male; Middle Aged; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; RNA, Messenger; Tyrosine | 1996 |
Protection against peroxynitrite dependent tyrosine nitration and alpha 1-antiproteinase inactivation by some anti-inflammatory drugs and by the antibiotic tetracycline.
Topics: Acetaminophen; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flufenamic Acid; Free Radical Scavengers; Humans; Mesalamine; Nitrates; Pancreatic Elastase; Penicillamine; Phenylbutazone; Tetracycline; Tyrosine | 1996 |
Peroxynitrite-mediated nitration of tyrosine residues in Escherichia coli glutamine synthetase mimics adenylylation: relevance to signal transduction.
Topics: Cations, Divalent; Escherichia coli; Glutamate-Ammonia Ligase; Manganese; Methionine; Nitrates; Signal Transduction; Structure-Activity Relationship; Tyrosine | 1996 |
Nitrotyrosine residues in placenta. Evidence of peroxynitrite formation and action.
Topics: Adult; Drug Residues; Female; Fetal Growth Retardation; Humans; Immunohistochemistry; Nitrates; Placenta; Pre-Eclampsia; Pregnancy; Tyrosine | 1996 |
Carbon dioxide enhancement of peroxynitrite-mediated protein tyrosine nitration.
Topics: Adult; Animals; Antioxidants; Bicarbonates; Blood Proteins; Carbon Dioxide; Catalysis; Cattle; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Nitrates; Proteins; Serum Albumin, Bovine; Tyrosine | 1996 |
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study.
Topics: Amyotrophic Lateral Sclerosis; Citrulline; Cyclic GMP; Cytoplasm; Humans; Immunohistochemistry; Motor Neurons; Neurofilament Proteins; Nitrates; Nitric Oxide; Nitrogen; Oxidation-Reduction; Superoxide Dismutase; Tyrosine | 1996 |
Protective effects of tirilazad mesylate in a cellular model of peroxynitrite toxicity.
Topics: Aminoisobutyric Acids; Animals; Biomarkers; Cells, Cultured; Cerebellum; Emulsions; Free Radical Scavengers; Lipid Peroxides; Nitrates; Pregnatrienes; Rats; Rats, Sprague-Dawley; Tyrosine | 1996 |
Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease.
Topics: Aged; Aged, 80 and over; Animals; Colon; Diverticulitis, Colonic; Female; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Middle Aged; Nitrates; Nitric Oxide Synthase; Rabbits; RNA, Messenger; Tyrosine | 1996 |
(-)-Epigallocatechin gallate, a polyphenolic tea antioxidant, inhibits peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catechin; Cattle; Deoxyguanosine; DNA; Free Radical Scavengers; Nitrates; Oxidation-Reduction; Tea; Tyrosine | 1996 |
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts.
Topics: Amino Acid Sequence; Analysis of Variance; Blotting, Western; Graft Rejection; Humans; Immunohistochemistry; Kidney; Kidney Transplantation; Models, Biological; Nitrates; Peptide Fragments; Superoxide Dismutase; Transplantation, Homologous; Tyrosine | 1996 |
Nitrotyrosine attenuates the hemodynamic effects of adrenoceptor agonists in vivo: relevance to the pathophysiology of peroxynitrite.
Topics: Adrenergic Agonists; Animals; Arginine Vasopressin; Hemodynamics; Male; Nitrates; Rats; Rats, Sprague-Dawley; Tyrosine | 1996 |
Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants.
Topics: alpha 1-Antitrypsin; Antioxidants; Arthritis, Rheumatoid; Ascorbic Acid; Humans; Lipid Peroxidation; Nitrates; Oxidation-Reduction; Oxidative Stress; Pancreatic Elastase; Synovial Fluid; Tyrosine | 1996 |
Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Blotting, Western; Cattle; Ferric Compounds; Kinetics; Lipid Peroxides; NAD; NADP; NADP Transhydrogenases; Nitrates; Oxidation-Reduction; Peptide Mapping; Stress, Physiological; Submitochondrial Particles; Tyrosine; Ubiquinone | 1996 |
The peroxynitrite product 3-nitro-L-tyrosine attenuates the hemodynamic responses to angiotensin II in vivo.
Topics: Anesthesia; Angiotensin II; Animals; Hemodynamics; Male; Nitrates; Pentobarbital; Rats; Rats, Sprague-Dawley; Tyrosine; Vasoconstrictor Agents | 1996 |
Formation of nitrosyl hemoglobin and nitrotyrosine during murine leishmaniasis.
Topics: Animals; Disease Models, Animal; Female; Hemoglobins; Leishmania mexicana; Leishmaniasis, Cutaneous; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Photobiology; Tyrosine | 1996 |
Peroxynitrite modification of glutathione reductase: modeling studies and kinetic evidence suggest the modification of tyrosines at the glutathione disulfide binding site.
Topics: Animals; Binding Sites; Blotting, Western; Cattle; Glutathione; Glutathione Reductase; Hydrogen Bonding; Intestinal Mucosa; Kinetics; Models, Molecular; NADP; Nitrates; Protein Binding; Protein Conformation; Solvents; Spectrometry, Fluorescence; Tyrosine | 1996 |
Prevention of peroxynitrite-dependent tyrosine nitration and inactivation of alpha1-antiproteinase by antibiotics.
Topics: alpha 1-Antitrypsin; Anti-Bacterial Agents; Free Radical Scavengers; Nitrates; Tyrosine | 1997 |
Peroxynitrite-induced tyrosine nitration and phosphorylation in human platelets.
Topics: Blood Platelets; Blood Proteins; Humans; Nitrates; P-Selectin; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Aggregation; Serotonin; Thrombin; Tyrosine | 1997 |
Antioxidant action of ergothioneine: assessment of its ability to scavenge peroxynitrite.
Topics: alpha 1-Antitrypsin; Antioxidants; Ergothioneine; Free Radical Scavengers; Nitrates; Tyrosine | 1997 |
Widespread peroxynitrite-mediated damage in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Entorhinal Cortex; Hippocampus; Humans; Immunohistochemistry; Middle Aged; Neurons; Nitrates; Oxidative Stress; Tyrosine | 1997 |
Inflammation and NO(X)-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection.
Topics: Animals; Blood Proteins; Cell Line; Chromatography, High Pressure Liquid; Electrochemistry; Gas Chromatography-Mass Spectrometry; Inflammation; Macrophage Activation; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred F344; Tyrosine; Zymosan | 1997 |
Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers.
Topics: alpha 1-Antitrypsin; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Nitrates; Thiourea; Tyrosine | 1997 |
Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Free Radicals; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Shock, Septic; Superoxides; Tyrosine | 1997 |
Interference of carboxy-PTIO with nitric oxide- and peroxynitrite-mediated reactions.
Topics: Animals; Benzoates; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Free Radical Scavengers; Imidazoles; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitrites; Serum Albumin, Bovine; Swine; Tyrosine | 1997 |
Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols.
Topics: Catechin; Free Radical Scavengers; Humans; Lipoproteins, LDL; Nitrates; Reference Standards; Tyrosine | 1997 |
Nitrotyrosine bound to beta-VLDL-apoproteins: a biomarker of peroxynitrite formation in experimental atherosclerosis.
Topics: Animals; Arteriosclerosis; Biomarkers; Blood Proteins; Cholesterol; Hypercholesterolemia; Lipoproteins, VLDL; Male; Nitrates; Rabbits; Triglycerides; Tyrosine | 1997 |
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.
Topics: Animals; Cell Count; Diabetes Mellitus, Type 1; Female; Islets of Langerhans; Leukocytes; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Nitrates; Tyrosine | 1997 |
Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis.
Topics: Endothelium, Vascular; Epithelium; Female; Humans; Immunohistochemistry; In Situ Hybridization; Lung; Macrophages, Alveolar; Male; Middle Aged; Nitrates; Oxidants; Pulmonary Fibrosis; Tyrosine | 1997 |
Free and protein-associated nitrotyrosine formation following rat liver preservation and transplantation.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Free Radicals; Humans; Liver; Liver Transplantation; Nitrates; Organ Preservation; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 1997 |
Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite.
Topics: Adolescent; Autopsy; Child; Child, Preschool; Densitometry; Female; Humans; Infant; Infant, Newborn; Male; Myocarditis; Nitrates; Nitrosation; Retrospective Studies; Sepsis; Tyrosine | 1997 |
Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation.
Topics: Arachidonic Acid; Blotting, Western; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrazines; Mutagens; Nitrates; Nitric Oxide; Nitrogen Oxides; Prostaglandin-Endoperoxide Synthases; Superoxide Dismutase; Tyrosine | 1997 |
Extensive peroxynitrite activity during progressive stages of central nervous system inflammation.
Topics: Animals; Antibody Specificity; Brain; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Free Radicals; Immunohistochemistry; Lipid Peroxidation; Mice; Mice, Inbred Strains; Neuritis, Autoimmune, Experimental; Neurons; Nitrates; Nitric Oxide; Spinal Cord; Staining and Labeling; Tyrosine | 1997 |
Peroxynitrite-mediated nitration of peptides: characterization of the products by electrospray and combined gas chromatography-mass spectrometry.
Topics: Chromatography, Liquid; Enkephalin, Leucine; Gas Chromatography-Mass Spectrometry; Hemoglobins; HIV Envelope Protein gp120; Mass Spectrometry; Nitrates; Peptide Fragments; Trimethylsilyl Compounds; Tyrosine | 1997 |
Direct ESR detection or peroxynitrite-induced tyrosine-centred protein radicals in human blood plasma.
Topics: Amino Acid Sequence; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Molecular Sequence Data; Nitrates; Sulfhydryl Compounds; Tyrosine; Uric Acid | 1997 |
What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
Topics: Biomarkers; Free Radicals; Humans; Molecular Structure; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrous Acid; Peroxidase; Superoxides; Tyrosine | 1997 |
Tyrosine nitration as a mechanism of selective inactivation of prostacyclin synthase by peroxynitrite.
Topics: Animals; Cattle; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Humans; Intramolecular Oxidoreductases; Nitrates; Nitric Oxide; Superoxides; Tyrosine | 1997 |
Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure.
Topics: Animals; Arginine; Carbon Monoxide; Cattle; Cell Survival; Cells, Cultured; Chromium; Endothelium, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidants; Oxidation-Reduction; Oxygen Consumption; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tyrosine | 1997 |
Thiols and disulphides can aggravate peroxynitrite-dependent inactivation of alpha1-antiproteinase.
Topics: alpha 1-Antitrypsin; Disulfides; Enzyme Activation; Hypochlorous Acid; Nitrates; Sulfhydryl Compounds; Tyrosine | 1997 |
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.
Topics: Animals; Apoptosis; Cells, Cultured; DNA; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Hippocampus; Lipid Peroxidation; Neurons; NF-kappa B; Nitrates; Nitrogen Compounds; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sphingosine; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine; Uric Acid | 1997 |
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite.
Topics: Amyotrophic Lateral Sclerosis; Animals; Binding Sites; Catalysis; Cloning, Molecular; Humans; Kinetics; Liver; Metallothionein; Models, Structural; Mutagenesis, Site-Directed; Mutation; Nitrates; Protein Conformation; Rabbits; Recombinant Proteins; Superoxide Dismutase; Tyrosine; Zinc | 1997 |
Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L.
Topics: Amino Acid Sequence; Animals; Humans; Kinetics; Mass Spectrometry; Mice; Neurofilament Proteins; Nitrates; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 1997 |
Role of peroxynitrite and activation of poly (ADP-ribose) synthase in the vascular failure induced by zymosan-activated plasma.
Topics: Animals; Aorta; Aorta, Thoracic; Blotting, Western; Cells, Cultured; DNA Damage; Enzyme Activation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Poly(ADP-ribose) Polymerases; Rats; Tyrosine; Zymosan | 1997 |
3-Nitrotyrosine in human serum albumin and low density lipoproteins.
Topics: Humans; Lipoproteins, LDL; Nitrates; Oxidants; Serum Albumin; Tyrosine | 1997 |
Nitration of platelet cytosolic proteins by peroxynitrite.
Topics: Blood Platelets; Blood Proteins; Collagen; Cytosol; Humans; In Vitro Techniques; Membrane Proteins; Nitrates; Oxidants; Tyrosine | 1997 |
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Topics: Animals; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Free Radical Scavengers; Immunoenzyme Techniques; Inflammation; Male; Melatonin; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Pleurisy; Rats; Rats, Sprague-Dawley; Tyrosine | 1997 |
Peroxynitrite modulates tyrosine-dependent signal transduction pathway of human erythrocyte band 3.
Topics: Amino Acid Sequence; Anion Exchange Protein 1, Erythrocyte; Erythrocytes; Glycolysis; Hemoglobins; Humans; In Vitro Techniques; Molecular Sequence Data; Nitrates; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1997 |
Evidence for the production of peroxynitrite in inflammatory CNS demyelination.
Topics: Acute Disease; Animals; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Female; Immunohistochemistry; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Recurrence; Remission Induction; Serum Albumin, Bovine; Spinal Cord; Tyrosine | 1997 |
Scavenging of hydroxyl radicals but not of peroxynitrite by inhibitors and substrates of nitric oxide synthases.
Topics: alpha 1-Antitrypsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Oxidants; Tyrosine | 1997 |
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Line; Cysteine Endopeptidases; Humans; Intracellular Membranes; Lipid Peroxidation; Membrane Lipids; Mice; Mice, Transgenic; Mitochondria; Neurons; Nitrates; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Tyrosine | 1998 |
Lipopolysaccharide-induced increase in plasma nitrotyrosine concentrations in rats.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Lipopolysaccharides; Male; Nitrates; Nitrites; Rats; Rats, Wistar; Tyrosine | 1997 |
Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Enzyme Inhibitors; Fetus; Free Radical Scavengers; Motor Neurons; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Rats; Spinal Cord; Superoxides; Tyrosine | 1998 |
Peroxynitrite formation in focal cerebral ischemia-reperfusion in rats occurs predominantly in the peri-infarct region.
Topics: Animals; Chromatography, High Pressure Liquid; Ischemic Attack, Transient; Male; Nitrates; Rats; Rats, Sprague-Dawley; Reperfusion; Tyrosine | 1998 |
Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues.
Topics: Crystallography, X-Ray; Cysteine; Enzyme Activation; Humans; Immunoblotting; Manganese; Models, Molecular; Nitrates; Oxidation-Reduction; Protein Binding; Superoxide Dismutase; Tyrosine | 1998 |
Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats.
Topics: Aging; Animals; Antioxidants; Biomarkers; Copper; Female; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrogen Peroxide; Hydroxyl Radical; Nitrates; Nitrogen; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Serum Albumin, Bovine; Tyrosine | 1998 |
Carbon dioxide stimulates peroxynitrite-mediated nitration of tyrosine residues and inhibits oxidation of methionine residues of glutamine synthetase: both modifications mimic effects of adenylylation.
Topics: Adenosine Monophosphate; Carbon Dioxide; Escherichia coli; Gene Expression Regulation, Enzymologic; Glutamate-Ammonia Ligase; Methionine; Models, Chemical; Models, Molecular; Nitrates; Oxidation-Reduction; Tyrosine | 1998 |
Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antibodies, Monoclonal; Blotting, Western; Colitis, Ulcerative; Colon; Enzyme Induction; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Isoenzymes; Male; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 1998 |
Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: nitration or electron donation?
Topics: Antioxidants; Caffeic Acids; Chlorogenic Acid; Chromans; Chromatography, High Pressure Liquid; Coumaric Acids; Free Radical Scavengers; Free Radicals; Nitrates; Spectrophotometry; Tyrosine | 1998 |
Plasma 3-nitrotyrosine is elevated in premature infants who develop bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Female; Humans; Infant, Newborn; Infant, Premature; Male; Nitrates; Oxidants; Oxidative Stress; Pilot Projects; Retrospective Studies; Tyrosine | 1998 |
Bilirubin is an effective antioxidant of peroxynitrite-mediated protein oxidation in human blood plasma.
Topics: Antioxidants; Bilirubin; Blood Proteins; Carbon Dioxide; Fluorescence; Humans; Hydrogen-Ion Concentration; Nitrates; Oxidation-Reduction; Peroxides; Sodium Bicarbonate; Spectrophotometry; Tryptophan; Tyrosine | 1998 |
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart; Hemodynamics; Histocytochemistry; Inflammation; Interleukin-1; Isoenzymes; Leukocyte Count; Microspheres; Myocardium; Nitrates; Nitric Oxide; Peroxidase; Tyrosine; Ventricular Dysfunction, Left | 1998 |
Nitric oxide production and perivascular tyrosine nitration following focal ischemia in neonatal rat.
Topics: Animals; Animals, Newborn; Brain; Cell Death; Female; Immunoenzyme Techniques; Ischemic Attack, Transient; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine | 1998 |
Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine.
Topics: Amino Acid Sequence; Enzyme Inhibitors; Humans; Mass Spectrometry; Mitochondria; Molecular Sequence Data; Nitrates; Peptide Fragments; Recombinant Proteins; Sequence Analysis; Serine Endopeptidases; Superoxide Dismutase; Tyrosine | 1998 |
Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Biotransformation; Liver; Male; Mice; Nitrates; Nitric Oxide; Proteins; Tyrosine | 1998 |
Modification of tissue factor by peroxynitrite influences its procoagulant activity.
Topics: Coagulants; Membrane Proteins; Monocytes; Nitrates; Oxidants; Recombinant Proteins; Thromboplastin; Tyrosine | 1998 |
Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat.
Topics: Animals; Asbestos, Crocidolite; Asbestos, Serpentine; Bronchoalveolar Lavage; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Inhalation Exposure; Lung; Macrophages; Macrophages, Alveolar; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Dioxide; Pleura; Pleural Effusion; Rats; Rats, Inbred F344; Reactive Oxygen Species; Tyrosine | 1998 |
Peroxynitrite uncloaked?
Topics: Free Radicals; Hydrogen-Ion Concentration; Isomerism; Kinetics; Nitrates; Oxidants; Tyrosine | 1998 |
Evidence for in vivo peroxynitrite production in human chronic hepatitis.
Topics: Adult; Antibodies; Antibody Specificity; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Immunohistochemistry; Liver Cirrhosis; Male; Middle Aged; Nitrates; Tyrosine | 1998 |
Nitration of the low molecular weight neurofilament is equivalent in sporadic amyotrophic lateral sclerosis and control cervical spinal cord.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Blotting, Western; Humans; Isoelectric Focusing; Middle Aged; Neurofilament Proteins; Nitrates; Precipitin Tests; Spinal Cord; Tyrosine | 1998 |
Neopterin derivatives modulate the nitration of tyrosine by peroxynitrite.
Topics: Hydrogen-Ion Concentration; Neopterin; Nitrates; Nitro Compounds; Pteridines; Pterins; Spectrophotometry; Tyrosine | 1998 |
Peroxynitrite formation within the central nervous system in active multiple sclerosis.
Topics: Central Nervous System; Humans; Immunohistochemistry; Inflammation; Multiple Sclerosis; Nervous System Diseases; Nitrates; Nitrites; Recurrence; Tyrosine | 1998 |
Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide.
Topics: Animals; Catalase; Catalysis; Horseradish Peroxidase; Hydrogen Peroxide; Hypochlorous Acid; Male; Myocardium; Nitrates; Nitrites; Peroxidase; Rats; Serum Albumin, Bovine; Tyrosine | 1998 |
Differential sensitivity of the tyrosyl radical of mouse ribonucleotide reductase to nitric oxide and peroxynitrite.
Topics: Animals; Coculture Techniques; DNA Replication; Free Radicals; Hydrogen Peroxide; Macrophage Activation; Macrophages, Peritoneal; Mice; NADPH Oxidases; Nitrates; Nitric Oxide; Ribonucleotide Reductases; Spectrophotometry, Atomic; Tumor Cells, Cultured; Tyrosine | 1998 |
Expression of thioredoxin is enhanced in atherosclerotic plaques and during neointima formation in rat arteries.
Topics: Animals; Arteriosclerosis; Carotid Arteries; Catheterization; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rats; Rats, Wistar; RNA, Messenger; Thioredoxins; Tumor Cells, Cultured; Tunica Intima; Tyrosine | 1998 |
Reduction of tyrosine nitration after N(omega)-nitro-L-arginine-methylester treatment of mice with traumatic brain injury.
Topics: Animals; Brain Injuries; Cerebral Cortex; Enzyme Inhibitors; Immunohistochemistry; Male; Mice; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Tyrosine | 1998 |
Inhibition of peroxynitrite-mediated tyrosine nitration by a novel pyrrolopyrimidine antioxidant.
Topics: Antioxidants; Erythrocyte Membrane; Humans; Nitrates; Oxidative Stress; Pyrimidines; Pyrrolidines; Tyrosine | 1998 |
Inhaled nitric oxide primes lung macrophages to produce reactive oxygen and nitrogen intermediates.
Topics: Administration, Inhalation; Animals; Antibodies; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Epithelial Cells; Interferon-gamma; Lipopolysaccharides; Lung; Macrophages, Alveolar; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen; Oxidants; Proteins; Pulmonary Alveoli; Reactive Oxygen Species; Superoxides; Tyrosine; Vasodilator Agents | 1998 |
Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock.
Topics: Analysis of Variance; Animals; Constriction; Enzyme Inhibitors; Ileum; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Shock; Splanchnic Circulation; Tyrosine | 1998 |
Role of peroxynitrite and poly (ADP-ribosyl) synthetase activation in cardiovascular derangement induced by zymosan in the rat.
Topics: Animals; Aortic Diseases; Benzamides; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Injections, Intraperitoneal; Male; Niacinamide; Nitrates; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Shock, Cardiogenic; Tyrosine; Zymosan | 1998 |
Lack of tyrosine nitration by peroxynitrite generated at physiological pH.
Topics: Carbon Dioxide; Free Radicals; Hydrogen-Ion Concentration; Models, Chemical; Molsidomine; Nitrates; Nitrogen Oxides; Spermine; Tyrosine; Xanthine Oxidase | 1998 |
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation.
Topics: Animals; Apoptosis; Benzamides; Caspase 1; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Hydrogen Peroxide; Immunohistochemistry; Mice; Nitrates; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thymus Gland; Tyrosine | 1998 |
Peroxynitrite is not a major mediator of endothelial cell injury by activated neutrophils in vitro.
Topics: Animals; Antibodies, Monoclonal; Cattle; CD18 Antigens; Cells, Cultured; Coculture Techniques; Deferoxamine; Dimethyl Sulfoxide; Endothelium, Vascular; Humans; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Penicillamine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Phosphatidylinositol 3-kinase is a target for protein tyrosine nitration.
Topics: Animals; Cell Line; Mice; Molecular Weight; Nitrates; Nitric Oxide Donors; Nitrogen Oxides; Phosphatidylinositol 3-Kinases; Protein Conformation; Proteins; Spermine; Tyrosine | 1998 |
Toxic effects of sulphite in combination with peroxynitrite on neuronal cells.
Topics: Animals; Cell Line; Cell Survival; DNA Fragmentation; Drug Combinations; Neurons; Nitrates; Oxidants; Rats; Sulfites; Tyrosine | 1998 |
Superoxide released from neutrophils causes a reduction in nitric oxide gas.
Topics: Animals; Cell Line; Cell Survival; Epithelial Cells; Gases; Humans; Hydrogen-Ion Concentration; Lung; Mice; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; RNA, Messenger; Superoxides; Tyrosine | 1998 |
Peroxynitrite formation and apoptosis in transgenic sickle cell mouse kidneys.
Topics: Anemia, Sickle Cell; Animals; Apoptosis; Blotting, Western; Immunohistochemistry; Kidney; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 1998 |
New aspects in the reaction mechanism of phenol with peroxynitrite: the role of phenoxy radicals.
Topics: Anisoles; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Nitrates; Nitrites; Nitrophenols; Oxygen; Phenol; Phenols; Tyrosine | 1998 |
Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Colitis; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Immunohistochemistry; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid; Tyrosine | 1998 |
Intra-coronary administration of L-arginine aggravates myocardial stunning through production of peroxynitrite in dogs.
Topics: Analysis of Variance; Animals; Arginine; Chromatography, High Pressure Liquid; Dogs; Enzyme Inhibitors; Female; Immunohistochemistry; Isomerism; Lipid Peroxidation; Male; Malondialdehyde; Microdialysis; Myocardial Contraction; Myocardial Stunning; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Random Allocation; Superoxide Dismutase; Tyrosine | 1998 |
Protective effects of melatonin in zymosan-activated plasma-induced paw inflammation.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Dose-Response Relationship, Drug; Edema; Foot; Free Radical Scavengers; Male; Melatonin; Nitrates; Oxidants; Plasma; Rats; Rats, Wistar; Tyrosine | 1998 |
Pulmonary vascular stress from carbon monoxide.
Topics: Animals; Capillaries; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Leukocytes; Lung; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Tyrosine; Vascular Diseases | 1999 |
Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response.
Topics: Antioxidants; Blood Proteins; Calcium; Cells, Cultured; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Oxidants; Pyrimidines; Pyrrolidines; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury.
Topics: Adenosine Diphosphate; Animals; Contusions; Female; Laminectomy; Nitrates; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tyrosine | 1999 |
Specific inhibition of iNOS decreases the intestinal mucosal peroxynitrite level and improves the barrier function after thermal injury.
Topics: Animals; Antioxidants; Bacterial Translocation; Body Surface Area; Burns; Coloring Agents; Enzyme Inhibitors; Female; Intestinal Mucosa; Intestine, Small; Isothiuronium; Liver; Lymph Nodes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rats; Rats, Sprague-Dawley; Spleen; Superoxides; Tyrosine | 1998 |
Antioxidant properties of the decarboxylated dimer of aminoethylcysteine ketimine: assessment of its ability to scavenge peroxynitrite.
Topics: alpha 1-Antitrypsin; Amino Acids, Sulfur; Antioxidants; Decarboxylation; Dimerization; Free Radical Scavengers; Humans; Lipoproteins, LDL; Nitrates; Oxidation-Reduction; Tyrosine | 1998 |
Evidence for peroxynitrite formation in the vasculature of women with preeclampsia.
Topics: Adult; Biopsy; Cesarean Section; Endothelium, Vascular; Female; Humans; Hysterectomy; Immunohistochemistry; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Pre-Eclampsia; Pregnancy; Superoxide Dismutase; Tyrosine | 1999 |
Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Coumarins; Cysteine Proteinase Inhibitors; DNA Primers; Enzyme Activation; Gene Expression Regulation, Enzymologic; Graft Rejection; Heart Transplantation; In Situ Nick-End Labeling; Mice; Mice, Inbred CBA; Mice, Knockout; Muscle Fibers, Skeletal; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligopeptides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; RNA, Messenger; Transplantation Immunology; Transplantation, Homologous; Tumor Suppressor Protein p53; Tyrosine | 1999 |
Peroxynitrite induces long-lived tyrosyl radical(s) in oxyhemoglobin of red blood cells through a reaction involving CO2 and a ferryl species.
Topics: Carbon Dioxide; Electron Spin Resonance Spectroscopy; Erythrocytes; Ferric Compounds; Free Radicals; Heme; Hemoglobins; Humans; Hydrogen Peroxide; Iron; Methemoglobin; Metmyoglobin; Nitrates; Oxidants; Oxygen; Oxyhemoglobins; Tyrosine | 1999 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan | 1999 |
Peroxynitrite formation during rat hepatic allograft rejection.
Topics: Animals; Blood Transfusion; Enzyme Inhibitors; Graft Rejection; Graft Survival; Liver Transplantation; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Inbred ACI; Rats, Inbred Lew; RNA, Messenger; Tacrolimus; Tissue Donors; Transplantation, Homologous; Transplantation, Isogeneic; Tyrosine | 1999 |
The effect of alpha-tocopherol on the nitration of gamma-tocopherol by peroxynitrite.
Topics: Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Liposomes; Molsidomine; Nitrates; Oxidants; Pentetic Acid; Stereoisomerism; Tyrosine; Vitamin E | 1999 |
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages.
Topics: Animals; Arteriosclerosis; Coronary Artery Bypass; Coronary Vessels; Cyclooxygenase 2; Graft Survival; Humans; Isoenzymes; Macrophages; Membrane Proteins; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Compounds; Prostaglandin-Endoperoxide Synthases; Rabbits; Tyrosine | 1999 |
Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death.
Topics: Apoptosis; CD3 Complex; Cell Division; Cells, Cultured; Dose-Response Relationship, Immunologic; Humans; Immunosuppressive Agents; Lymph Nodes; Lymphocyte Activation; Metalloporphyrins; Monocytes; Nitrates; Nitric Oxide Synthase; Phosphorylation; Proteins; Superoxide Dismutase; T-Lymphocytes; Time Factors; Tyrosine | 1999 |
Detection of 3-nitrotyrosine in human platelets exposed to peroxynitrite by a new gas chromatography/mass spectrometry assay.
Topics: Blood Platelets; Fluorobenzenes; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitrogen Dioxide; Sensitivity and Specificity; Tyrosine | 1998 |
Oxidative stress occurs in perfused rat liver at low oxygen tension by mechanisms involving peroxynitrite.
Topics: Animals; Ethanol; Female; Free Radicals; Glycogen; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Nitrates; Oxidants; Oxidative Stress; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Tyrosine | 1999 |
A kinetic model of the system: tyrosyl radical-nitrogen oxide-superoxide ion.
Topics: Arteriosclerosis; Free Radicals; Humans; Ions; Lipid Peroxidation; Lipoproteins, LDL; Models, Chemical; Nitrates; Nitrogen Oxides; Superoxides; Tyrosine | 1999 |
Increased peroxynitrite activity in AIDS dementia complex: implications for the neuropathogenesis of HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS Dementia Complex; Brain Chemistry; Female; HIV Infections; HIV-1; Humans; Immunohistochemistry; Interleukin-1; Interleukin-10; Macrophages; Male; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Superoxide Dismutase; Superoxides; Tyrosine | 1999 |
Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia.
Topics: Animals; Azides; Cell Survival; Cells, Cultured; Enzyme Activation; Glutamate Dehydrogenase; Inflammation; Ketoglutarate Dehydrogenase Complex; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Mitochondria; Nitrates; Nitric Oxide; Oxidative Stress; Oxidoreductases; Oxygen Consumption; Reactive Oxygen Species; Tyrosine | 1999 |
Prostaglandin endoperoxide-dependent vasospasm in bovine coronary arteries after nitration of prostacyclin synthase.
Topics: Angiotensin II; Animals; Carbon Radioisotopes; Cattle; Coronary Vasospasm; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinoprostone; Epoprostenol; Immunohistochemistry; In Vitro Techniques; Intramolecular Oxidoreductases; Nitrates; Oxidants; Potassium Chloride; Prostaglandin Antagonists; Prostaglandin H2; Prostaglandins; Prostaglandins H; Proteins; Tyrosine; Vasoconstriction; Vasodilation | 1999 |
Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Epithelium; Glutathione Peroxidase; Hydrogen Peroxide; Liver; Nitrates; Nitric Oxide; Phosphorylation; Rats; Sodium Selenite; Time Factors; Tyrosine | 1999 |
Inhibition of peroxynitrite dependent DNA base modification and tyrosine nitration by the extra virgin olive oil-derived antioxidant hydroxytyrosol.
Topics: Animals; Antioxidants; Cattle; Chronic Disease; DNA; DNA Damage; Humans; Hybrid Cells; Mice; Neuroblastoma; Neurons; Nitrates; Nitric Oxide; Olive Oil; Oxidants; Phenylethyl Alcohol; Plant Oils; Rats; Retina; Superoxides; Tyrosine | 1999 |
In vivo disposition of 3-nitro-L-tyrosine in rats: implications on tracking systemic peroxynitrite exposure.
Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Infusions, Intravenous; Male; Nitrates; Oxidants; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tyrosine | 1999 |
Modulation of peroxynitrite- and hypochlorous acid-induced inactivation of alpha1-antiproteinase by mercaptoethylguanidine.
Topics: alpha 1-Antitrypsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Humans; Hypochlorous Acid; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 1999 |
Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants.
Topics: Ascorbic Acid; Catalysis; Free Radical Scavengers; Glutathione; Hydrogen-Ion Concentration; Isomerism; Kinetics; Metalloporphyrins; Nitrates; Oxidants; Oxidation-Reduction; Porphyrins; Reducing Agents; Tyrosine; Uric Acid | 1999 |
Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (Y34F) by peroxynitrite.
Topics: Catalytic Domain; Humans; Mutation; Nitrates; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 1999 |
High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation.
Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Disease Models, Animal; Female; L-Lactate Dehydrogenase; Lung; Macrophages, Alveolar; Mice; Mice, Inbred C57BL; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; T-Lymphocytes; Time Factors; Tyrosine | 1999 |
Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.
Topics: Aging; Amino Acid Sequence; Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cysteine; Endopeptidases; Isoenzymes; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Nitrates; Nitric Oxide; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Sarcoplasmic Reticulum; Sulfhydryl Compounds; Tyrosine | 1999 |
Analysis of 3-nitrotyrosine in biological fluids and protein hydrolyzates by high-performance liquid chromatography using a postseparation, on-line reduction column and electrochemical detection: results with various nitrating agents.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Hypochlorous Acid; Indicators and Reagents; Molsidomine; Nitrates; Nitrites; Nitrogen Oxides; Serum Albumin, Bovine; Sodium Nitrite; Spectrophotometry, Ultraviolet; Spermine; Tyrosine | 1999 |
Inhibition of GTP binding to Rac2 by peroxynitrite: potential role for tyrosine modification.
Topics: Animals; Binding Sites; Fluorescent Dyes; Free Radicals; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Nitrates; Oxidants; rac GTP-Binding Proteins; Reactive Oxygen Species; Recombinant Proteins; Tyrosine | 1999 |
Inhibition of peroxynitrite-mediated oxidation of dopamine by flavonoid and phenolic antioxidants and their structural relationships.
Topics: Antioxidants; Caffeic Acids; Catechin; Chromatography, High Pressure Liquid; Coumaric Acids; Dopamine; Flavonoids; Monophenol Monooxygenase; Nitrates; Oxidation-Reduction; Phenols; Propionates; Structure-Activity Relationship; Tyrosine | 1999 |
Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation.
Topics: Carbon Dioxide; Escherichia coli; Glutamate-Ammonia Ligase; Glycine max; Hydrogen-Ion Concentration; Kinetics; Lipid Peroxidation; Lipoxygenase; Methionine; Models, Chemical; Nitrates; Oxidants; Oxidation-Reduction; Serum Albumin, Bovine; Tyrosine | 1999 |
The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat.
Topics: Animals; Carrageenan; Cells, Cultured; Disease Models, Animal; Free Radical Scavengers; Glutathione; Macrophages; Nitrates; Nitric Oxide; Oxidants; Pleurisy; Protective Agents; Rats; Tyrosine | 1999 |
Tyrosine nitration in blood vessels occurs with increasing nitric oxide concentration.
Topics: Animals; Aorta, Thoracic; Cattle; In Vitro Techniques; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen; Rabbits; Superoxides; Tyrosine | 1999 |
p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite.
Topics: Crk-Associated Substrate Protein; Humans; Molsidomine; Neuroblastoma; Nitrates; Nitric Oxide Donors; Oxidants; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured; Tyrosine | 1999 |
Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage.
Topics: Animals; Brain; Cerebral Infarction; Citrulline; Corpus Striatum; Enzyme Activation; Functional Laterality; Immunohistochemistry; Injections, Intraperitoneal; Ischemic Attack, Transient; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Microinjections; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidants; Tyrosine | 1999 |
Denitration of peroxynitrite-treated proteins by "protein nitratases" from dog prostate.
Topics: Animals; beta-Fructofuranosidase; Blotting, Western; Dithiothreitol; Dogs; Enzyme Activation; Glutathione Transferase; Glycoside Hydrolases; Histones; Male; Nitrates; Oxidoreductases; Polylysine; Prostate; Serum Albumin; Tissue Extracts; Tyrosine | 1999 |
Peroxynitrite induces tryosine nitration and modulates tyrosine phosphorylation of synaptic proteins.
Topics: Animals; Brain; Brain Chemistry; Cattle; Dose-Response Relationship, Drug; Nitrates; Nitric Oxide; Oxidants; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Synapses; Synaptophysin; Synaptosomes; Tyrosine | 1999 |
Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro.
Topics: Chemokine CCL5; Chemotaxis; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrazines; Interleukin-5; Leukotriene B4; Molsidomine; Nitrates; Nitric Oxide; Nitrogen; Pteridines; Reactive Oxygen Species; Superoxides; Tyrosine; Xanthine | 1999 |
Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxins; Nitrates; Oxidants; Porphyrins; Reference Values; Tyrosine | 1999 |
Radical mechanisms of the decomposition of peroxynitrite and the peroxynitrite-CO(2) adduct and of reactions with L-tyrosine and related compounds as studied by (15)N chemically induced dynamic nuclear polarization.
Topics: Carbon Dioxide; Free Radicals; Magnetic Resonance Spectroscopy; Nitrates; Tyrosine | 1999 |
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Topics: Animals; Benzamides; Complement Activation; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Free Radicals; Immunohistochemistry; Inflammation; Male; Niacinamide; Nitrates; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tyrosine; Zymosan | 1999 |
Effects of exogenous nitric oxide and hyperoxia on lung fibroblast viability and DNA fragmentation.
Topics: Antioxidants; Catalase; Cell Survival; Cells, Cultured; DNA Fragmentation; Fibroblasts; Humans; Hyperoxia; In Situ Nick-End Labeling; Lung; Nitrates; Nitric Oxide; Oxygen; Superoxides; Tyrosine | 1999 |
Formation and loss of nitrated proteins in peroxynitrite-treated rat skin in vivo.
Topics: Animals; Kinetics; Male; Nitrates; Oxidants; Proteins; Rats; Rats, Wistar; Serum Albumin, Bovine; Skin; Time Factors; Tyrosine | 1999 |
Role of peroxynitrite as a mediator of pathophysiological alterations in experimental pneumococcal meningitis.
Topics: Animals; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Free Radical Scavengers; Inflammation; Intracranial Pressure; Leukocytes; Male; Meningitis, Pneumococcal; Nitrates; Oxidants; Rats; Rats, Wistar; Subarachnoid Space; Tyrosine; Uric Acid | 1999 |
Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro.
Topics: Blood Physiological Phenomena; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Monocytes; Nitrates; Nitrogen; Oxidants; Reactive Oxygen Species; Reducing Agents; Superoxides; Tyrosine | 1999 |
Rapid and irreversible inactivation of protein tyrosine phosphatases PTP1B, CD45, and LAR by peroxynitrite.
Topics: Aniline Compounds; Anions; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Leukocyte Common Antigens; Models, Molecular; Molsidomine; Nitrates; Nitric Oxide; Nitroso Compounds; Organophosphates; Organophosphorus Compounds; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; S-Nitrosoglutathione; Superoxide Dismutase; Tyrosine | 1999 |
Vascular peroxynitrite formation during organic nitrate tolerance.
Topics: Animals; Aorta, Thoracic; Blood Proteins; Drug Tolerance; Immunohistochemistry; Male; Nitrates; Nitroglycerin; Rats; Rats, Sprague-Dawley; Tyrosine; Vasodilator Agents | 1999 |
IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.
Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Celiac Artery; Constriction; Cytokines; Ileum; Immunity, Innate; Intercellular Adhesion Molecule-1; Interleukin-6; Ischemia; Leukocyte Count; Lipid Peroxidation; Malondialdehyde; Mesenteric Artery, Superior; Mice; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Reperfusion Injury; Shock; Splanchnic Circulation; Tyrosine | 1999 |
In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
Topics: Aldehydes; Alzheimer Disease; Analysis of Variance; Biomarkers; DNA Damage; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Histocytochemistry; Humans; Iron; Membrane Proteins; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenylhydrazines; Plaque, Amyloid; Tyrosine | 1999 |
Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: evidence for neutrophil-mediated hydroxylation, nitration, and chlorination.
Topics: Adolescent; Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Linear Models; Male; Middle Aged; Neutrophil Activation; Neutrophils; Nitrates; Oxidants; Oxidative Stress; Proteins; Respiration, Artificial; Respiratory Distress Syndrome; Statistics, Nonparametric; Tyrosine | 1999 |
Inhibitory mechanism of sinapinic acid against peroxynitrite-mediated tyrosine nitration of protein in vitro.
Topics: Chromatography, High Pressure Liquid; Coumaric Acids; Dimerization; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitrates; Oxidation-Reduction; Proteins; Tyrosine | 1999 |
Increased expression of inducible nitric oxide synthase and peroxynitrite in Helicobacter pylori gastric ulcer.
Topics: Fluorescent Antibody Technique; Gastric Mucosa; Gastritis; Helicobacter pylori; Humans; Macrophages; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptic Ulcer; Tyrosine | 1999 |
Effects of reactive oxygen species on brain synaptic plasma membrane Ca(2+)-ATPase.
Topics: Age Factors; Amidines; Animals; Azo Compounds; Brain; Calcium; Calcium-Transporting ATPases; Hydrogen Peroxide; Kinetics; Male; Nitrates; Oxidative Stress; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Synaptic Membranes; Tyrosine; Urea; Valerates | 1999 |
Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase.
Topics: Animals; Blood Circulation; Cattle; Cells, Cultured; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Nitrates; Nitric Oxide; Signal Transduction; Superoxides; Tyrosine | 1999 |
Role of IL-6 in the pleurisy and lung injury caused by carrageenan.
Topics: Animals; Carrageenan; Cells, Cultured; Cytokines; Dinoprostone; DNA Damage; Enzyme Induction; Interleukin-6; Leukotriene B4; Lung; Macrophages; Male; Malondialdehyde; Mice; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Tyrosine | 1999 |
Modification of proteins and polynucleotides by peroxynitrite.
Topics: Animals; Nitrates; Nitric Oxide; Oxidants; Proteins; Rabbits; Tyrosine | 1999 |
Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo.
Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Dogs; Echocardiography; Female; Interleukin-1; Male; Myocardium; Nitrates; Random Allocation; Stroke Volume; Superoxides; Thiazoles; Tyrosine; Ventricular Dysfunction, Left | 1999 |
The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat.
Topics: Animals; Carrageenan; Cells, Cultured; Energy Metabolism; Lipid Peroxidation; Macrophages; Melatonin; Nitrates; Nitric Oxide; Peroxidase; Pleurisy; Rats; Tyrosine | 1999 |
Factors determining the selectivity of protein tyrosine nitration.
Topics: Amino Acid Sequence; Models, Molecular; Molecular Sequence Data; Muramidase; Nitrates; Nitric Oxide; Phospholipases A; Protein Processing, Post-Translational; Protein Structure, Secondary; Ribonuclease, Pancreatic; Sequence Analysis, Protein; Superoxides; Tyrosine | 1999 |
Immunohistochemical nitrotyrosine distribution in neonatal rat cerebrocortical slices during and after hypoxia.
Topics: Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypoxia-Ischemia, Brain; N-Methylaspartate; Neurons; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Superoxides; Tyrosine | 1999 |
Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan.
Topics: Animals; Antioxidants; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Kidney; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Melatonin; Nitrates; Rats; Rats, Sprague-Dawley; Shock; Tyrosine; Zymosan | 1999 |
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acids; Animals; Brain; Chelating Agents; Dopamine Agents; Free Radicals; Gas Chromatography-Mass Spectrometry; Male; Mice; Mice, Inbred C57BL; Nitrates; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Pentetic Acid; Tissue Distribution; Tyrosine | 1999 |
Peroxynitrite inactivation of tyrosine hydroxylase: mediation by sulfhydryl oxidation, not tyrosine nitration.
Topics: Bicarbonates; Enzyme Activation; Nitrates; Oxidants; Oxidation-Reduction; Pyrimidines; Pyrroles; Sulfhydryl Compounds; Tetranitromethane; Tyrosine; Tyrosine 3-Monooxygenase | 1999 |
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Metalloporphyrins; NAD; Nitrates; Peroxidase; Rats; Rats, Sprague-Dawley; Shock; Superoxide Dismutase; Tyrosine; Zymosan | 1999 |
Protection against peroxynitrite by cocoa polyphenol oligomers.
Topics: Biflavonoids; Cacao; Catechin; Flavonoids; Nitrates; Oxidants; Oxidation-Reduction; Phenols; Polymers; Proanthocyanidins; Protective Agents; Rhodamines; Tyrosine | 1999 |
NOX, a novel nitric oxide scavenger, reduces bacterial translocation in rats after endotoxin challenge.
Topics: Animals; Bacteremia; Enterobacteriaceae; Enterocytes; Free Radical Scavengers; Infusion Pumps, Implantable; Intestinal Absorption; Intestines; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Thiocarbamates; Tyrosine | 1999 |
Denitration of peroxynitrite-treated proteins by 'protein nitratases' from rat brain and heart.
Topics: Animals; beta-Fructofuranosidase; Blotting, Western; Brain; Brain Chemistry; Calcium; Dialysis; Enzymes; Flavin-Adenine Dinucleotide; Glutathione; Glutathione Transferase; Glycoside Hydrolases; Myocardium; NAD; NADP; Nitrates; Proteins; Rats; Serum Albumin, Bovine; Tissue Extracts; Tyrosine | 1999 |
Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscle.
Topics: Animals; Diastole; Immunoenzyme Techniques; Male; Myocardial Contraction; Nitrates; Oxidants; Papillary Muscles; Rats; Systole; Tyrosine | 1999 |
Tyrosine nitration by simultaneous generation of (.)NO and O-(2) under physiological conditions. How the radicals do the job.
Topics: Animals; Free Radicals; Humans; Nitrates; Tyrosine | 2000 |
Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cardiovascular Diseases; Endothelium, Vascular; Hemodynamics; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; Nitrates; Nitroprusside; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Renin; Tyrosine; Vasoconstriction | 2000 |
Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion.
Topics: Acidosis; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Endothelium, Vascular; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen; Reperfusion Injury; Tyrosine | 2000 |
Dityrosine formation outcompetes tyrosine nitration at low steady-state concentrations of peroxynitrite. Implications for tyrosine modification by nitric oxide/superoxide in vivo.
Topics: Dimerization; Flavin Mononucleotide; Free Radicals; Hydrazines; Hypoxanthine; Kinetics; Nitrates; Nitric Oxide; Nitrogen Oxides; Spermine; Tyrosine; Xanthine Oxidase | 2000 |
Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: relevance to colon carcinogenesis.
Topics: Apoptosis; Bile Acids and Salts; Colonic Neoplasms; Deoxycholic Acid; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radical Scavengers; Humans; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Salicylates; Superoxides; Tumor Cells, Cultured; Tyrosine | 1999 |
Western blot analysis for nitrotyrosine protein adducts in livers of saline-treated and acetaminophen-treated mice.
Topics: Acetaminophen; Adjuvants, Immunologic; Analgesics, Non-Narcotic; Animals; Blotting, Western; Cattle; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Hemocyanins; Immunoenzyme Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Necrosis; Nitrates; Protein Binding; Proteins; Rabbits; Serum Albumin, Bovine; Sodium Chloride; Tyrosine | 2000 |
Scavengers for peroxynitrite: inhibition of tyrosine nitration and oxidation with tryptamine derivatives, alpha-lipoic acid and synthetic compounds.
Topics: Antioxidants; Chromatography, High Pressure Liquid; DNA Damage; Free Radical Scavengers; Indicators and Reagents; Nitrates; Oxidation-Reduction; Plasmids; Spectrophotometry, Ultraviolet; Spin Trapping; Thioctic Acid; Tryptamines; Tyrosine | 2000 |
Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy.
Topics: Animals; Carrageenan; Cells, Cultured; Cyclic N-Oxides; DNA Damage; Free Radical Scavengers; Hydrogen Peroxide; Lung; Macrophages; Male; Mitochondria; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxygen Consumption; Permeability; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spin Labels; Tyrosine | 2000 |
Rapid reactions of peroxynitrite with heme-thiolate proteins as the basis for protection of prostacyclin synthase from inactivation by nitration.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hemeproteins; Horseradish Peroxidase; Intramolecular Oxidoreductases; Kinetics; Models, Biological; Nitrates; Tyrosine | 2000 |
Diffusion of peroxynitrite into the human platelet inhibits cyclooxygenase via nitration of tyrosine residues.
Topics: Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diffusion; Eicosanoids; Gas Chromatography-Mass Spectrometry; Humans; Immunoblotting; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Membrane Proteins; Nitrates; Oxidants; Platelet Activation; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Tyrosine; Vasoconstriction | 2000 |
Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Free Radical Scavengers; Mice; Multiple Sclerosis; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Spinal Cord; Tyrosine; Uric Acid | 2000 |
Responses to peroxynitrite in yeast: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination.
Topics: Animals; Astrocytes; Cell Culture Techniques; Cell Survival; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Fungal Proteins; Glyceraldehyde-3-Phosphate Dehydrogenases; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Molecular Chaperones; Nitrates; Oxidants; Rats; Rats, Wistar; Saccharomyces cerevisiae; Sulfhydryl Compounds; Sulfhydryl Reagents; Tyrosine; Ubiquitins; Up-Regulation | 2000 |
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Angiotensin II; Antihypertensive Agents; Diabetes Mellitus, Type 1; Epoprostenol; Female; Fetus; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Reactive Oxygen Species; Tyrosine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Reactive nitrogen and oxygen species attenuate interleukin- 8-induced neutrophil chemotactic activity in vitro.
Topics: Chemotaxis, Leukocyte; Humans; Interleukin-8; Leukotriene B4; Molsidomine; Neutrophils; Nitrates; Nitric Oxide Donors; Tyrosine | 2000 |
Involvement of peroxynitrite and hydroxyradical generated from nitric oxide in hypoxia/reoxygenation injury in rat cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Cell-Free System; Cerebral Cortex; Cyclic AMP; Enzyme Inhibitors; Hydroxyl Radical; Hypoxia; Male; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Tyrosine | 2000 |
Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases.
Topics: Adult; Aged; Alzheimer Disease; Antibodies; Biomarkers; Female; Humans; Male; Middle Aged; Nitrates; Nitrogen; Oxidative Stress; Parkinson Disease; Precipitin Tests; Superoxide Dismutase; Tyrosine | 2000 |
Peroxynitrite-mediated nitration of the stable free radical tyrosine residue of the ribonucleotide reductase small subunit.
Topics: Amino Acid Sequence; Catalysis; Chromatography, High Pressure Liquid; Conserved Sequence; Dimerization; Dose-Response Relationship, Drug; Escherichia coli; Free Radicals; Hydrogen-Ion Concentration; Mass Spectrometry; Models, Molecular; Molecular Weight; Nitrates; Nonheme Iron Proteins; Protein Structure, Quaternary; Ribonucleotide Reductases; Sequence Analysis, Protein; Spectrophotometry; Tyrosine | 2000 |
Hyperalgesia due to nerve injury-role of peroxynitrite.
Topics: Animals; Hyperalgesia; Hyperthermia, Induced; Immunohistochemistry; Male; Nerve Compression Syndromes; Nerve Crush; Nerve Degeneration; Neuralgia; Nitrates; Peripheral Nerve Injuries; Peripheral Nerves; Rats; Rats, Wistar; Tyrosine; Uric Acid | 2000 |
Formation of N-nitrosamines and N-nitramines by the reaction of secondary amines with peroxynitrite and other reactive nitrogen species: comparison with nitrotyrosine formation.
Topics: Aniline Compounds; Hydrogen Peroxide; Hypochlorous Acid; Morpholines; Nitrates; Nitrobenzenes; Nitrosamines; Sodium Nitrite; Superoxides; Tyrosine | 2000 |
Role of the carbonate radical anion in tyrosine nitration and hydroxylation by peroxynitrite.
Topics: Anions; Bicarbonates; Carbon Dioxide; Carbonates; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Nitrates; Nitric Oxide; Spectrophotometry, Ultraviolet; Tyrosine | 2000 |
Plasma proteins modified by tyrosine nitration in acute respiratory distress syndrome.
Topics: Acute Disease; Adult; alpha 1-Antichymotrypsin; Blood Proteins; Blotting, Western; Carbon Dioxide; Ceruloplasmin; Enzyme Activation; Fibrinogen; Humans; In Vitro Techniques; Nitrates; Nitric Oxide; Oxidative Stress; Precipitin Tests; Respiratory Distress Syndrome; Superoxides; Tyrosine | 2000 |
Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages.
Topics: Carbon Dioxide; Cells, Cultured; Enzyme Activation; Epithelial Cells; Humans; Hypercapnia; Lipid Metabolism; Lipopolysaccharides; Macrophages, Alveolar; Mass Spectrometry; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Oxidation-Reduction; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Respiratory Distress Syndrome; Tyrosine | 2000 |
Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Child; Diabetic Nephropathies; Female; Humans; Immunohistochemistry; Kidney; Male; Middle Aged; Nitrates; Tyrosine | 2000 |
The nitration of platelet cytosolic proteins during agonist-induced activation of platelets.
Topics: Aspirin; Blood Platelets; Blood Proteins; Blotting, Western; Cell Adhesion Molecules; Collagen; Cyclooxygenase Inhibitors; Cytosol; Enzyme-Linked Immunosorbent Assay; Humans; Membrane Proteins; Microfilament Proteins; Molecular Weight; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrous Acid; Oxidants; Peroxynitrous Acid; Phosphoproteins; Platelet Activation; Thrombin; Tyrosine | 2000 |
A catalyst of peroxynitrite decomposition inhibits murine experimental autoimmune encephalomyelitis.
Topics: Animals; Catalysis; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Female; Ferric Compounds; Immunohistochemistry; Lymphocyte Transfusion; Lymphocytes; Metalloporphyrins; Mice; Mice, Inbred Strains; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 2000 |
Role of nitric oxide in lipopolysaccharide-induced oxidant stress in the rat kidney.
Topics: Animals; Blood Urea Nitrogen; Blotting, Western; Creatine; Enzyme Inhibitors; Glutathione; Immunohistochemistry; Kidney; Lipid Peroxidation; Lipopolysaccharides; Lysine; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2000 |
Poly(ADP-ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain.
Topics: Animals; Animals, Newborn; Benzamides; Brain Ischemia; Cell Death; Cerebral Infarction; Encephalitis; Female; Male; Motor Activity; Neurologic Examination; Neuroprotective Agents; Neutrophils; Nitrates; Poly(ADP-ribose) Polymerase Inhibitors; Polymers; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Stroke; Time Factors; Tyrosine | 2000 |
Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis.
Topics: Adult; Alternative Splicing; Arginine; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; DNA-Binding Proteins; Epithelial Cells; Female; Fluocinolone Acetonide; Humans; Interferon-gamma; Janus Kinase 1; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Reactive Oxygen Species; RNA, Messenger; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Tyrosine | 2000 |
Scavenging of peroxynitrite by oxyhemoglobin and identification of modified globin residues.
Topics: Ascorbic Acid; Carbon Dioxide; Dipeptides; Erythrocytes; Free Radical Scavengers; Globins; Humans; Immunoelectrophoresis; Mass Spectrometry; Nitrates; Oxyhemoglobins; Tyrosine | 2000 |
Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Blood Pressure; Catalysis; Celiac Artery; Disease Models, Animal; Endothelium, Vascular; Ferric Compounds; Ileum; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rhodamines; Splanchnic Circulation; Tyrosine | 2000 |
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma.
Topics: Adenocarcinoma; Blotting, Western; Chromatography, High Pressure Liquid; Cortactin; Humans; Microfilament Proteins; Nitrates; Pancreatic Neoplasms; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Conformation; Protein Folding; Proto-Oncogene Proteins pp60(c-src); Tumor Cells, Cultured; Tyrosine | 2000 |
Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage.
Topics: Albumins; Animals; Coenzymes; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Immunoblotting; Kinetics; Mitochondria; Mitochondria, Liver; Models, Chemical; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Oxygen Consumption; Protein Binding; Rats; Spectrophotometry; Time Factors; Tyrosine; Ubiquinone | 2000 |
Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice.
Topics: Animals; Antibiotics, Antineoplastic; Creatine Kinase; Doxorubicin; Immunohistochemistry; Male; Mice; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine; Ventricular Dysfunction, Left | 2000 |
Peroxynitrite-generating species: good candidate oxidants in aqueous extracts of cigarette smoke.
Topics: Arteriosclerosis; Humans; Nicotiana; Nitrates; Oxidants; Plants, Toxic; Smoke; Smoking; Tyrosine | 2000 |
Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys.
Topics: Alanine Transaminase; Anemia, Sickle Cell; Animals; Apoptosis; Aspartate Aminotransferases; Blotting, Western; Cell Hypoxia; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Guanidines; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Diseases; Kidney Tubules; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Poly(ADP-ribose) Polymerases; Tyrosine | 2000 |
Helicobacter pylori urease suppresses bactericidal activity of peroxynitrite via carbon dioxide production.
Topics: Ammonia; Anti-Bacterial Agents; Carbon Dioxide; Drug Interactions; Helicobacter pylori; Microbial Sensitivity Tests; Nitrates; Oxidants; Sodium Bicarbonate; Tyrosine; Urea; Urease | 2000 |
Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase.
Topics: Humans; Kinetics; Nitrates; Nitric Oxide; Oxidants; Peroxidase; Sputum; Superoxides; Tyrosine; Xanthine Oxidase | 2000 |
Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite.
Topics: Hydrogen-Ion Concentration; Kinetics; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidants; Photochemistry; Spectrophotometry; Spermine; Superoxides; Tyrosine; Xanthine Oxidase | 2000 |
Reactions of peroxynitrite with cocoa procyanidin oligomers.
Topics: Biflavonoids; Cacao; Catechin; Chromatography, High Pressure Liquid; Drug Interactions; Nitrates; Oxidants; Oxidation-Reduction; Proanthocyanidins; Rhodamines; Structure-Activity Relationship; Tyrosine | 2000 |
Immunolocalization of inducible nitric oxide synthase and 3-nitrotyrosine in the nasal mucosa of patients with rhinitis.
Topics: Adolescent; Adult; Enzyme Induction; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Nasal Mucosa; Nitrates; Nitric Oxide Synthase; Rhinitis; Rhinitis, Allergic, Perennial; Turbinates; Tyrosine | 2000 |
Physiological effects of peroxynitrite: potential products of the environment.
Topics: Animals; Blood Physiological Phenomena; Cats; Crystalloid Solutions; Cytokines; Glutathione; Heart; Heart Diseases; Heart Ventricles; Humans; Isotonic Solutions; Myocardial Infarction; Nitrates; Nitric Oxide; Perfusion; Plasma Substitutes; Superoxides; Tyrosine | 2000 |
Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Coloring Agents; Endothelium, Vascular; Enzyme Inhibitors; Evans Blue; Indazoles; Infarction, Middle Cerebral Artery; Matrix Metalloproteinase 9; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidants; Permeability; Reperfusion Injury; Tyrosine | 2000 |
Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats.
Topics: Animals; Animals, Newborn; Brain Diseases; Carotid Arteries; Hypoxia-Ischemia, Brain; Kinetics; Ligation; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RNA, Messenger; Tyrosine | 2000 |
Nitric oxide synthase and tissue injury.
Topics: Alprostadil; Animals; Arginine; Burns; Enzyme Inhibitors; Humans; Ischemia; Luminescent Measurements; Models, Biological; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Reperfusion Injury; Sepsis; Shock; Superoxides; Tyrosine | 2000 |
Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Carbachol; Genistein; Humans; Molsidomine; Neuroblastoma; Nitrates; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2000 |
P-selectin participates in cardiopulmonary bypass-induced inflammatory response in association with nitric oxide and peroxynitrite production.
Topics: Animals; Antibodies, Monoclonal; Cardiopulmonary Bypass; Inflammation; Interleukin-6; Male; Nitrates; Nitric Oxide; Nitrites; P-Selectin; Rats; Rats, Sprague-Dawley; Tyrosine | 2000 |
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury.
Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Aorta; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Ileum; In Vitro Techniques; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitrites; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splenic Artery; Tyrosine; Vasodilation | 2000 |
Nitration and hydroxylation of aromatic amino acid and guanine by the air pollutant peroxyacetyl nitrate.
Topics: Air Pollutants; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Guanine; HL-60 Cells; Humans; Hydroxylation; Mass Spectrometry; Nitrates; Nitrogen; Oxidants; Peracetic Acid; Phenylalanine; Tryptophan; Tyrosine | 2000 |
Chromium (VI) increases endothelial cell expression of ICAM-1 and decreases nitric oxide activity.
Topics: Cells, Cultured; Endothelium, Vascular; Free Radicals; Humans; Intercellular Adhesion Molecule-1; Nitrates; Nitric Oxide; Nitrites; Potassium Dichromate; RNA, Messenger; Superoxides; Tyrosine | 2000 |
Effects of homocysteine on endothelial nitric oxide production.
Topics: Animals; Arginine; Bradykinin; Calcimycin; Cells, Cultured; Endothelium, Vascular; Folic Acid; Free Radical Scavengers; Homocysteine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Reactive Oxygen Species; Recombinant Proteins; Superoxides; Tyrosine | 2000 |
Suppression of the development of hypertension by the inhibitor of inducible nitric oxide synthase.
Topics: Animals; Aorta; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Hypertension; Immunoassay; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Thiocarbamates; Tyrosine; Vasodilation | 2000 |
Application of chemically induced dynamic nuclear polarization to the nitration of N-acetyltyrosine and to some reactions of peroxynitrite.
Topics: Absorption; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrates; Nitric Acid; Nitrites; Nitrobenzenes; Nitrogen Isotopes; Tyrosine | 2000 |
Overexpression of neutrophil neuronal nitric oxide synthase in Parkinson's disease.
Topics: Blotting, Western; Enzyme Induction; Female; Humans; Hydrogen Peroxide; Male; Middle Aged; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parkinson Disease; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrophotometry; Tyrosine | 2000 |
The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein.
Topics: Amino Acids; Animals; Immunohistochemistry; Male; Models, Biological; Nitrates; Nitric Oxide; Nitroarginine; Proteins; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Superoxide Dismutase; Tyrosine; Wounds, Nonpenetrating | 2000 |
Reactions of peroxynitrite in the mitochondrial matrix.
Topics: Animals; Ascorbic Acid; Blotting, Western; Carbon Dioxide; Glutathione; Inhibitory Concentration 50; Kinetics; Mice; Mitochondria, Liver; NAD; Nitrates; Oxidation-Reduction; Spectrometry, Fluorescence; Superoxides; Tyrosine; Ubiquinone | 2000 |
Dopamine-melanin protects against tyrosine nitration, tryptophan oxidation and Ca(2+)-ATPase inactivation induced by peroxynitrite.
Topics: Animals; Antioxidants; Calcium-Transporting ATPases; Cattle; Erythrocyte Membrane; Humans; Kinetics; Melanins; Nitrates; Oxidants; Oxidation-Reduction; Serum Albumin, Bovine; Tryptophan; Tyrosine | 2000 |
Role of nitric oxide and superoxide in acute cardiac allograft rejection in rats.
Topics: Acute Disease; Animals; Electron Spin Resonance Spectroscopy; Graft Rejection; Heart Transplantation; In Vitro Techniques; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Perfusion; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Superoxide Dismutase; Superoxides; Transplantation, Homologous; Tyrosine | 2000 |
Autocatalytic nitration of P450CAM by peroxynitrite.
Topics: Binding Sites; Blotting, Western; Camphor 5-Monooxygenase; Carbon Monoxide; Catalysis; Cytochrome P-450 Enzyme System; Heme; Hydroxylation; Intramolecular Oxidoreductases; Kinetics; Ligands; Mass Spectrometry; Models, Molecular; Nitrates; Nitrogen; Phenol; Protein Binding; Protein Conformation; Protons; Spectrophotometry; Time Factors; Tyrosine | 2000 |
Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway.
Topics: Animals; Apoptosis; Carbon Dioxide; Cells, Cultured; Cytokines; Fetus; Hypercapnia; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pulmonary Alveoli; Rats; Respiratory Mucosa; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts.
Topics: Androstadienes; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Molsidomine; Morpholines; Nitrates; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Skin; Time Factors; Tyrosine; Tyrphostins; Wortmannin | 2000 |
Effects of propofol on endothelial cells subjected to a peroxynitrite donor (SIN-1).
Topics: Anesthetics, Intravenous; Cell Culture Techniques; Cell Death; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Molsidomine; Nitrates; Nitric Oxide Donors; Propofol; Tyrosine | 2000 |
Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan.
Topics: Animals; Carrageenan; Cells, Cultured; DNA Damage; Enzyme Activation; Exudates and Transudates; Immunohistochemistry; Lipid Peroxidation; Lung; Macrophages; Male; Malondialdehyde; Mice; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Tyrosine | 2000 |
Mechanism for the peroxynitrite scavenging activity by anthocyanins.
Topics: Anthocyanins; Chromatography, High Pressure Liquid; Free Radical Scavengers; Kinetics; Nitrates; Nitrobenzoates; Oxidants; Parabens; Tyrosine | 2000 |
Nitration and inactivation of cytochrome P450BM-3 by peroxynitrite. Stopped-flow measurements prove ferryl intermediates.
Topics: Animals; Bacillus; Bacterial Proteins; Binding Sites; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dithiothreitol; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Inhibitory Concentration 50; Iron; Mass Spectrometry; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Molsidomine; NADPH-Ferrihemoprotein Reductase; Nitrates; Nitric Oxide Donors; Nitrogen; Oxygen; Superoxide Dismutase; Temperature; Time Factors; Tyrosine; Uric Acid | 2000 |
Inflammatory properties of IgG modified by oxygen radicals and peroxynitrite.
Topics: Acute Disease; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Binding Sites, Antibody; Complement C1q; Complement C3; Female; Free Radicals; Gout; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunoglobulin G; Male; Neutrophils; Nitrates; Osteoarthritis; Oxidation-Reduction; Oxygen; Rabbits; Receptors, IgG; Serum Albumin, Bovine; Synovial Fluid; Tyrosine | 2000 |
GnRH agonist-suppressed expression of nitric oxide synthases and generation of peroxynitrite in adenomyosis.
Topics: Adult; Endometriosis; Endometrium; Epithelial Cells; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Humans; Luteal Phase; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Stromal Cells; Tyrosine | 2000 |
A reevaluation of the peroxynitrite scavenging activity of some dietary phenolics.
Topics: alpha 1-Antitrypsin; Bicarbonates; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Diet; Free Radical Scavengers; Gallic Acid; Kinetics; Nitrates; Oxidants; Pancreatic Elastase; Phenols; Structure-Activity Relationship; Tyrosine | 2000 |
Peroxynitrite formation in the orbit of diabetics with rhinocerebral mucormycosis.
Topics: Adolescent; Adult; Aged; Brain Diseases; Diabetes Mellitus; Eye Infections, Fungal; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Mucormycosis; Nitrates; Orbital Diseases; Paranasal Sinus Diseases; Respiratory Burst; Tyrosine | 2000 |
Enhanced peroxynitrite formation is associated with vascular aging.
Topics: Acetylcholine; Aging; Animals; Aorta; Body Weight; Calcimycin; Cellular Senescence; Endothelium, Vascular; Enzyme Induction; Hemodynamics; Male; Microscopy, Immunoelectron; Mitochondria; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxidative Stress; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tyrosine; Vasodilation | 2000 |
LC-MS/MS detection of peroxynitrite-derived 3-nitrotyrosine in rat microvessels.
Topics: Animals; Brain; Chromatography, Liquid; Mass Spectrometry; Microcirculation; Microscopy, Phase-Contrast; Nitrates; Rats; Rats, Wistar; Sensitivity and Specificity; Tyrosine | 2000 |
A novel procedure for generating both nitric oxide and superoxide in situ from chemical sources at any chosen mole ratio. First application: tyrosine oxidation and a comparison with preformed peroxynitrite.
Topics: Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidants; Oxidation-Reduction; Spermine; Superoxides; Tyrosine | 2000 |
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.
Topics: Blood; Cell Line; Cell Movement; Complement Activation; Deferoxamine; Dithiothreitol; Embryo, Mammalian; Fibroblasts; Fibronectins; Humans; Lung; Molsidomine; Nitrates; Nitric Oxide Donors; Nitrogen; Reactive Oxygen Species; Reducing Agents; Superoxides; Tyrosine; Xanthine Oxidase | 2001 |
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterial Occlusive Diseases; Catalysis; Cytokines; Fluorescent Antibody Technique; Ileum; Leukocyte Count; Male; Malondialdehyde; Manganese; Nitrates; Nitrites; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Superoxide Dismutase; Superoxides; Tyrosine | 2001 |
Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase.
Topics: Animals; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxins; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reference Values; Superoxide Dismutase; Tyrosine | 2001 |
Adenovirus infection increases iNOS and peroxynitrite production in the lung.
Topics: Adenoviridae Infections; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Female; Immunohistochemistry; Lung; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pulmonary Surfactants; Tyrosine | 2001 |
Antioxidative properties of phenolic antioxidants isolated from corn steep liquor.
Topics: Acetates; Animals; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Erythrocyte Membrane; Fermentation; Lipoproteins; Magnetic Resonance Spectroscopy; Nitrates; Phenols; Rabbits; Tyrosine; Vitamin E; Zea mays | 2001 |
Aging-related expression of inducible nitric oxide synthase and markers of tissue damage in the rat penis.
Topics: Aging; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Collagen; Cysteine Endopeptidases; DNA Fragmentation; Gene Expression Regulation, Enzymologic; Image Processing, Computer-Assisted; In Situ Nick-End Labeling; Male; Multienzyme Complexes; Muscle, Smooth; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Penis; Proteasome Endopeptidase Complex; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tyrosine; Ubiquitins | 2001 |
Endogenous and new synthetic antioxidants for peroxynitrite: selective inhibitory effect of 5-methoxytryptamine and lipoic acid on tyrosine nitration by peroxynitrite.
Topics: 5-Methoxytryptamine; Antioxidants; Chromatography, High Pressure Liquid; Dopamine Agents; Levodopa; Nitrates; Oxidants; Oxidation-Reduction; Proline; Pyrrolidines; Thioctic Acid; Tyrosine | 1999 |
Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure.
Topics: Animals; Creatine Kinase; Creatine Kinase, MM Form; Heart Failure; Image Processing, Computer-Assisted; Immunohistochemistry; Isoenzymes; Male; Myofibrils; Myosins; Nitrates; Oxidants; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Peroxynitrite inhibits the activity of ornithine decarboxylase.
Topics: Animals; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Nitrates; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidants; Rats; Recombinant Proteins; Tyrosine | 2001 |
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.
Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Reference Values; Superoxides; Tamoxifen; Tyrosine | 2001 |
Chemical evaluation of compounds as nitric oxide or peroxynitrite donors using the reactions with serotonin.
Topics: Aerobiosis; Chromatography, High Pressure Liquid; Copper; Glutathione; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; S-Nitrosoglutathione; Serotonin; Tyrosine | 2001 |
Effect of peroxynitrite on motor function of the opossum esophagus.
Topics: Animals; Enzyme Inhibitors; Esophagitis; Esophagogastric Junction; Female; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitrates; Opossums; Oxadiazoles; Oxidants; Oxyhemoglobins; Quinoxalines; Tyrosine | 2001 |
Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase, and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells.
Topics: Aniline Compounds; Animals; Antioxidants; Blotting, Western; Cattle; Cell Death; Enzyme Inhibitors; Epithelial Cells; Female; Free Radical Scavengers; Histidine; L-Lactate Dehydrogenase; Lipopolysaccharides; Mammary Glands, Animal; Molsidomine; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 2001 |
Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, nitric oxide donors, and purine derivatives.
Topics: Molecular Structure; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Purines; Sulfhydryl Compounds; Tyrosine; Uric Acid | 2001 |
Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.
Topics: Eosinophil Peroxidase; Eosinophils; Free Radicals; Humans; Immunohistochemistry; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxidants; Oxidation-Reduction; Peroxidases; Phenylpropionates; Proteins; Reactive Oxygen Species; Status Asthmaticus; Tyrosine | 2001 |
Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro.
Topics: Animals; Base Sequence; Cell Line; DNA Primers; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Hydrazines; Lung; Mice; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; RNA, Messenger; Tyrosine | 2001 |
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
Topics: Acetylcysteine; Animals; Blotting, Western; Carrageenan; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Erythrocytes; Free Radical Scavengers; I-kappa B Proteins; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lung; Macrophages; Male; Malondialdehyde; Neutrophils; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases.
Topics: Adenocarcinoma; Animals; Azoles; Bradykinin; Capillary Permeability; Collagenases; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Precursors; Free Radical Scavengers; Gelatinases; Guinea Pigs; Isoindoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Nitrates; Oligopeptides; Organoselenium Compounds; Protease Inhibitors; Sarcoma 180; Skin; Tyrosine; Uric Acid | 2001 |
Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Death; Colitis; Colon; Disease Models, Animal; Epithelial Cells; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxides; Trinitrobenzenesulfonic Acid; Tyrosine | 2001 |
Nitric oxide and Coxsackievirus B3 myocarditis: differential expression of inducible nitric oxide synthase in mouse heart after infection with virulent or attenuated virus.
Topics: Animals; Disease Models, Animal; Enterovirus; Guanosine Monophosphate; Heart; Immunohistochemistry; Male; Mice; Myocarditis; Myocardium; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nucleic Acid Hybridization; RNA, Viral; Tyrosine | 2001 |
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Glycoproteins; Mercury Poisoning, Nervous System; Methylmercury Compounds; Nerve Degeneration; Neurons; Nitrates; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2001 |
In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation.
Topics: Annexin A5; Apoptosis; Cells, Cultured; Child, Preschool; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; In Situ Nick-End Labeling; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Stromal Cells; Superoxide Dismutase; Superoxides; T-Lymphocytes; Thymus Gland; Tyrosine | 2001 |
Site-selective nitration of tyrosine in human serum albumin by peroxynitrite.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Molecular Structure; Nitrates; Peptides; Serum Albumin; Tyrosine | 2001 |
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution.
Topics: Bicarbonates; Cyclic N-Oxides; Free Radicals; Hydroxyl Radical; Lipid Bilayers; Liposomes; Mass Spectrometry; Membranes, Artificial; Molsidomine; Nitrates; Nitrosation; Oxidation-Reduction; Solutions; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spin Labels; Tyrosine; Water | 2001 |
Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite.
Topics: Animals; Cell Line; Cytokines; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Free Radical Scavengers; Hydrogen Peroxide; Immunoblotting; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitrates; Nitric Oxide; Nitrites; Nitrogen; Oxygen; Peroxidase; Recombinant Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; Zymosan | 2001 |
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Caspases; Cell Division; Cell Line; Dermatitis, Contact; DNA Damage; DNA Fragmentation; Female; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Interleukin-8; Keratinocytes; Mice; Mice, Inbred Strains; Necrosis; Nitrates; Oxazolone; Poly(ADP-ribose) Polymerases; Skin; Tyrosine | 2001 |
Myoglobin-catalyzed tyrosine nitration: no need for peroxynitrite.
Topics: Animals; Horses; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Metmyoglobin; Myocardium; Myoglobin; Nitrates; Nitrites; Oxidation-Reduction; Tyrosine | 2001 |
Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite.
Topics: Animals; Catechin; Cell-Free System; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Fluoresceins; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipoxygenase; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitrates; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulfhydryl Compounds; Tyrosine | 2001 |
Preconditioning decreases ischemia/reperfusion-induced peroxynitrite formation.
Topics: Animals; Aorta; Blood Flow Velocity; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nitrates; Rats; Rats, Wistar; Time Factors; Tyrosine; Ventricular Function, Left | 2001 |
Peroxynitrite causes endothelial cell monolayer barrier dysfunction.
Topics: Actins; Animals; beta Catenin; Cell Survival; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Kinetics; Molsidomine; Nitrates; Nitric Oxide; Nitric Oxide Donors; Oxidants; Pulmonary Artery; Reactive Oxygen Species; Superoxide Dismutase; Swine; Trans-Activators; Tyrosine | 2001 |
-OONO: rebounding from nitric oxide.
Topics: Administration, Inhalation; Animals; Endothelium, Vascular; Epoprostenol; Hemoglobins; Humans; Hydroxyl Radical; Hypertension, Pulmonary; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Pneumonia; Prostaglandin H2; Prostaglandins H; Signal Transduction; Superoxides; Tyrosine | 2001 |
Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cells, Cultured; Dioxoles; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Humans; Hypertension, Pulmonary; Lung; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Receptor, Endothelin A; Secondary Prevention; Sheep; Superoxides; Tyrosine | 2001 |
Oxidative stress and reactive nitrogen species generation during renal ischemia.
Topics: Aldehydes; Animals; Blood Urea Nitrogen; Creatinine; Free Radicals; Glutathione; Kidney; Male; Nitrates; Oxidation-Reduction; Oxidative Stress; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Tyrosine | 2001 |
Peroxynitrite formation from human myocardium after ischemia-reperfusion during open heart operation.
Topics: Adult; Aged; Cardiopulmonary Bypass; Creatine Kinase; Creatine Kinase, MB Form; Female; Heart Valve Prosthesis Implantation; Humans; Isoenzymes; Male; Malondialdehyde; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Nitrates; Tyrosine | 2001 |
Acute hyperglycemia induces an oxidative stress in healthy subjects.
Topics: Adult; Biomarkers; Confounding Factors, Epidemiologic; Diabetic Angiopathies; Female; Glucose Clamp Technique; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hyperglycemia; Male; Nitrates; Oxidative Stress; Tyrosine; Vasoconstriction | 2001 |
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C.
Topics: Animals; Brain; Cysteine; Isoenzymes; Male; Neurodegenerative Diseases; Nitrates; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; Penicillamine; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tissue Extracts; Tyrosine | 2001 |
Expressions of nitrotyrosine and TUNEL immunoreactivities in cultured rat spinal cord neurons after exposure to glutamate, nitric oxide, or peroxynitrite.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Central Nervous System Diseases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radicals; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Motor Neurons; Nerve Degeneration; Neurons; Neurotoxins; Nitrates; Nitric Oxide Donors; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spinal Cord; Tyrosine | 2001 |
Aging increases the susceptiblity to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Fever; Homovanillic Acid; Male; Methamphetamine; Nitrates; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation.
Topics: Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Female; Immunosuppressive Agents; Interferon-gamma; Macrophages; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Pneumonia; Survival Rate; T-Lymphocytes; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Peroxynitrite-induced nitrotyrosination of proteins is blocked by direct 5-lipoxygenase inhibitor zileuton.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Nitrates; omega-N-Methylarginine; Precipitin Tests; Proteins; Rats; Rats, Wistar; Tyrosine | 2001 |
Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants.
Topics: Acetates; Acetylcholine; Animals; Antioxidants; Biological Transport; Carbon Radioisotopes; Choline; Choline O-Acetyltransferase; Drug Interactions; Molsidomine; Nitrates; Oxidants; Reducing Agents; Torpedo; Tyrosine; Uric Acid | 2001 |
Partial protection by poly(ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes.
Topics: Animals; Apoptosis; Benzamides; Caspases; Cells, Cultured; DNA Damage; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mitochondria; Nitrates; Nitrites; Nitrogen Oxides; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protective Agents; Thymus Gland; Tyrosine | 2001 |
Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver.
Topics: Adenocarcinoma; Aged; Apoptosis; Cell Division; Colorectal Neoplasms; Female; Humans; Immunoenzyme Techniques; Liver Neoplasms; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxidative Stress; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Tyrosine | 2002 |
Evaluation of nitrotyrosine-containing proteins in blood platelets.
Topics: Animals; Blood Platelets; Blotting, Western; Cattle; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Nitrates; Serum Albumin, Bovine; Tyrosine | 2004 |
Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation.
Topics: Flavonoids; Models, Chemical; Models, Molecular; Nitrates; Nitrogen; Structure-Activity Relationship; Thermodynamics; Tyrosine | 2005 |
15N CIDNP investigations of the peroxynitric acid nitration of L-tyrosine and of related compounds.
Topics: Ascorbic Acid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitrates; Nitrogen; Nitrogen Isotopes; Phenols; Solvents; Temperature; Tyrosine | 2006 |