tyrosine has been researched along with oligonucleotides in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (28.89) | 18.7374 |
| 1990's | 14 (15.56) | 18.2507 |
| 2000's | 38 (42.22) | 29.6817 |
| 2010's | 12 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khorana, HG | 1 |
| Belagaje, R; Brown, EL; Fritz, HJ; Khorana, HG; Lees, RG | 1 |
| Khorana, HG; Ormondt, HV; Sekiua, T | 1 |
| Ikehara, M | 1 |
| Contreras, R; Khorana, HG; Küpper, H; Landy, A | 1 |
| Crawford, AM; Phua, SH; Wood, NJ | 1 |
| Kay, CM; McCubbin, WD; Pearlstone, JR; Smillie, LB; Sykes, BD | 1 |
| Huskey, SE; Lu, AY; McKeever, BM; Newton, DJ; Pickett, CB; Wang, RW | 1 |
| Abeles, RH; Epstein, DM | 1 |
| Chen, N; Chen, S; Su, C; Zhang, D; Zhi, G | 1 |
| Abraham, N; Veillette, A | 1 |
| Alessandrini, AA; Crews, CM; Erikson, RL | 1 |
| Andrews, AE; Lawley, B; Pittard, AJ | 1 |
| Chung, DW; Davie, EW; Farrell, DH; Huang, SM; Mulvihill, ER | 1 |
| De Martynoff, G; Mercken, L; Simons, MJ; Swillens, S; Vassart, G | 1 |
| Tener, GM; White, BN | 1 |
| Philippsen, P; Zachau, G | 1 |
| Philippsen, P; Zachau, HG | 1 |
| Gefter, ML; Reinitz, ER; Yang, S | 1 |
| Barrett, JC; Miller, PS; Ts'o, PO | 1 |
| Chang, SE; Smith, JD | 1 |
| Hussain, Z; Ofengand, J | 1 |
| Celis, JE; Hooper, ML; Smith, JD | 1 |
| Cary, L; Kearns, DR; Lightfoot, DR; Reid, BR; Shulman, RG; Wong, KL; Wong, YP | 1 |
| Grunberger, D; Pulkrabek, P; Weinstein, IB | 1 |
| Caruthers, MH | 1 |
| Khorana, HG; Sekiya, T | 1 |
| Khorana, HG; Loewen, PC | 1 |
| Gefter, ML; Manley, J; Reiness, G; Zubay, G | 1 |
| Chakraburtty, K; Mehler, AH | 1 |
| Baas, PD; Jansz, HS; Van Mansfeld, AD | 1 |
| Boschelli, F | 1 |
| Baltimore, D; Crawford, NM | 1 |
| Gur'ev, SO; Iarotskiĭ, SV; Tialina, IuIu; Trakhanova, MN | 1 |
| Backer, JM; Batzer, A; Daly, R; Lee, CH; Myers, MJ; Skolnik, EY; Ullrich, A; Vicentini, LM; White, MF; Zhou, M | 1 |
| Ansari, RA; Khan, SA; Schmidt, MC; Zhao, AC | 1 |
| Alix, AJ; Berjot, M; Bronstein, IB; Dodson, GG; Feofanov, AV; Fleury, F; Holden, JA; Ianoul, A; Jardillier, JC; Kryukov, E; Kudelina, I; Maizieres, M; Nabiev, I; Sukhanova, A; Wilkinson, AJ; Wynne-Jones, A | 1 |
| Geisler, C; Gerwien, J; Labuda, T; Nielsen, M; Nissen, MH; Odum, N; Röpke, C; Svejgaard, A | 1 |
| Confalonieri, F; de La Tour, CB; Déclais, AC; Duguet, M; Marsault, J | 1 |
| Eklund, EA; Jalava, A; Kakar, R | 1 |
| Bezrookove, V; Raap, AK; Tanke, HJ; van de Corput, MP; van Gijlswijk, RP; Wiegant, J | 1 |
| Ellington, AD; Marshall, KA | 1 |
| Gray, CW; Gray, DM; Mou, TC; Terwilliger, TC | 1 |
| Gatto, B; Palumbo, M; Vianini, E | 1 |
| Cobbs, CS; Gillespie, GY; Harkins, LE; MacMillan-Crow, LA; Merrick, BA; Samanta, M | 1 |
| Chen, HC; Chuang, LY; Guh, JY; Huang, JS; Hung, WC; Lai, YH | 1 |
| Acharya, N; Handa, P; Varshney, U | 1 |
| Andrejic, J; Eklund, EA; Goldenberg, I; Kakar, R; Lu, Y | 1 |
| Arora, T; He, H; Kim, J; Liu, B; Modlin, RL; Murphy, KM; Murphy, TL; Shuai, K | 1 |
| Chien, W; Fermin, AC; Kettenbach, A; Koeffler, HP; Krug, U; Roifman, CM; Shih, LY; Tidow, N; Williamson, EA | 1 |
| Beaulieu, ME; Boucard, AA; Escher, E; Guillemette, G; Lavigne, P; Leduc, R; Roy, M | 1 |
| Arman, A; Auron, PE | 1 |
| Benedetti, P; Bruselles, A; Chillemi, G; Desideri, A; Falconi, M; Fiorani, P | 1 |
| Imbert, V; Livolsi, A; Peyron, JF; Siddiqui, A; Waris, G | 1 |
| HERBERT, E; SMITH, CJ; WILSON, CW | 2 |
| Aebersold, R; Berk, BC; Haendeler, J; Heller, M; Hojo, Y; Melaragno, M; Saito, Y; Sharma, VK; Yan, C; Yin, G | 1 |
| Lu, Y; Pollak, M; Zhao, Y; Zi, X | 1 |
| Brown, TA; Carter, WG; Dunn, CA; Knudsen, B; Sigle, RO; Xia, Y; Yang, TM; Zaitsevskaia, T | 1 |
| Fanelli, F; Martens, JW; Themmen, AP; Timmerman, M; Verhoef-Post, M; Zeilemaker, A | 1 |
| Coulombe, RA; Rieben, WK | 1 |
| Arora, PD; El Sayegh, TY; Kapus, A; Laschinger, CA; Lee, W; McCulloch, CA; Morrison, C; Overall, CM | 1 |
| Boucard, AA; Clément, M; Escher, E; Guillemette, G; Leduc, R; Martin, SS | 1 |
| Croteau, DL; DellaVecchia, MJ; Kisker, C; Mandavilli, BS; Skorvaga, M; Theis, K; Truglio, JJ; Van Houten, B | 1 |
| Brierley, MM; Fish, EN | 1 |
| Enns, A; Fisch, KM; Gassmann, P; Haier, J; Nicolson, GL; von Sengbusch, A | 1 |
| Kerman, K; Morita, Y; Takamura, Y; Tamiya, E | 1 |
| Bouvier, M; Demarre, G; Mazel, D | 1 |
| Jewhurst, SA; Robertson, NB; Waite, JH; Zhao, H | 1 |
| Achuthan, A; Elsegood, C; Hamilton, JA; Masendycz, P; Scholz, GM | 1 |
| Kong, SK; Kwok, TT; Tsang, WP | 1 |
| Kool, ET; Lai, J; Shuman, S; Yakovleva, L | 1 |
| Bohr, VA; Fan, J; Harrigan, JA; Momand, J; Perrino, FW; Wilson, DM | 1 |
| Davies, AM; Gallagher, D; Gavalda, N; Gutierrez, H; Hay, R; O'Keeffe, G | 1 |
| Ohmori, T; Sakata, Y; Ueki, M; Yamaguchi, M | 1 |
| Ahn, H; Choi, J; Han, NJ; Lee, KU; Lee, SK; Park, SK; Seo, JW; Yang, WS | 1 |
| Chantler, PD; Wylie, SR | 1 |
| Gerasimova, YV; Godovikova, TS; Knorre, DD; Shakirov, MM | 1 |
| Cheng, H; Frost, JA; Kirken, RA; Nagy, ZS; Ross, JA | 1 |
| Cabezas, M; de la Cruz, F; González-Pérez, B; Lucas, M; Moncalian, G; Rivas, G | 1 |
| Diederichs, K; Marx, A; Obeid, S; Welte, W | 1 |
| Kennis, JT; Mathes, T; Stierl, M; van Stokkum, IH | 1 |
| Chan, L; Corbalán-Campos, J; Hartmann, P; Heyll, K; Nazari-Jahantigh, M; Schober, A; Thiemann, A; Weber, C; Wei, Y; Zhu, M | 1 |
| Sachdeva, A; Silverman, SK; Walsh, SM | 1 |
| Challier, L; Fave, C; Lalaoui, N; Limoges, B; Mavré, F; Moreau, J; Noël, V; Schöllhorn, B | 1 |
| Bahn, M; Cheong, SW; Ju, BG; Kim, WS; Kim, YH; Kim, YJ; Shin, JY; Yeo, CY | 1 |
| Barnett, BL; Dunford, JE; Ebetino, FH; Evdokimov, A; Kavanagh, KL; Kwaasi, AA; Muniz, JR; Oppermann, U; Pilka, ES; Russell, RGG; Tsoumpra, MK; Von Delft, F; Walter, RL | 1 |
| Agudo, R; Blanco, L; Calvo, PA; Martínez-Jiménez, MI | 1 |
| Cetin, AE; Otles, S; Ozyurt, VH; Topkaya, SN | 1 |
| Lüder, CGK; Meyer, T; Nast, R; Staab, J | 1 |
2 review(s) available for tyrosine and oligonucleotides
| Article | Year |
|---|---|
Total synthesis of a gene.
Topics: Base Sequence; DNA-Directed RNA Polymerases; DNA, Recombinant; Escherichia coli; Genes; Genes, Regulator; Hydrogen Bonding; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; RNA, Transfer; Suppression, Genetic; Transcription, Genetic; Tyrosine | 1979 |
Some questions about the structure and activity of aminoacyl-tRNA synthetases.
Topics: Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Cations, Divalent; Inosine; Isoleucine; Isomerism; Kinetics; Methionine; Methylation; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Phenylalanine; Protein Binding; Pseudouridine; Ribonucleotides; RNA, Transfer; Species Specificity; Sulfhydryl Compounds; Sulfur; Tyrosine; Uracil; Valine | 1971 |
88 other study(ies) available for tyrosine and oligonucleotides
| Article | Year |
|---|---|
Total synthesis of a tyrosine suppressor transfer RNA gene. XIV. Chemical synthesis of oligonucleotide segments corresponding to the terminal regions.
Topics: Base Sequence; Chromatography, High Pressure Liquid; DNA, Bacterial; Escherichia coli; Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; RNA, Transfer; Suppression, Genetic; Tyrosine | 1979 |
The nucleotide sequence in the promoter region of the fene for an Escherichia coli tyrosine transfer ribonucleic acid.
Topics: Base Sequence; Chromatography, Thin Layer; DNA Nucleotidyltransferases; DNA, Bacterial; Escherichia coli; Genes; Kinetics; Nucleic Acid Hybridization; Nucleotidyltransferases; Oligonucleotides; Polynucleotide Ligases; Ribonucleotides; RNA, Bacterial; RNA, Transfer; Transcription, Genetic; Tyrosine | 1975 |
Synthesis of ribo-oligonucleotides having the sequence of transfer ribonucleic acid.
Topics: Alanine; Base Sequence; Methods; Nucleic Acid Conformation; Oligonucleotides; Oligoribonucleotides; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Tyrosine | 1975 |
Promoter-dependent transcription of tRNAITyr genes using DNA fragments produced by restriction enzymes.
Topics: Adenosine Triphosphate; Base Sequence; Cytosine Nucleotides; DNA Restriction Enzymes; DNA, Bacterial; Endonucleases; Escherichia coli; Genes; Guanosine Triphosphate; Heparin; Oligonucleotides; Rifampin; RNA Nucleotidyltransferases; RNA, Transfer; Transcription, Genetic; Tyrosine | 1975 |
A dinucleotide repeat polymorphism at the glycine- and tyrosine-rich keratin locus in sheep.
Topics: Animals; Base Sequence; Chromosome Mapping; Glycine; Keratins; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Polymorphism, Genetic; Repetitive Sequences, Nucleic Acid; Sheep; Tyrosine | 1992 |
Spectroscopic analysis of a methionine-48 to tyrosine mutant of chicken troponin C.
Topics: Animals; Base Sequence; Calcium; Cations, Divalent; Chickens; Circular Dichroism; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methionine; Molecular Sequence Data; Mutation; Oligonucleotides; Spectrophotometry, Ultraviolet; Troponin; Troponin C; Tyrosine | 1992 |
Site-directed mutagenesis of glutathione S-transferase YaYa. Important roles of tyrosine 9 and aspartic acid 101 in catalysis.
Topics: Animals; Aspartic Acid; Base Sequence; Blotting, Western; Catalysis; Cloning, Molecular; Escherichia coli; Fluorescence; Glutathione Transferase; Hydrogen-Ion Concentration; Immunochemistry; Kinetics; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Polymerase Chain Reaction; Rats; Sulfhydryl Compounds; Tyrosine | 1992 |
Role of serine 214 and tyrosine 171, components of the S2 subsite of alpha-lytic protease, in catalysis.
Topics: Base Sequence; Blotting, Western; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Protein Conformation; Restriction Mapping; Serine; Serine Endopeptidases; Tyrosine | 1992 |
Significance of the 56th tyrosine on cytotoxic activity of tumor necrosis factor.
Topics: Base Sequence; Cytotoxicity, Immunologic; Gene Expression Regulation; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Tyrosine | 1992 |
Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation.
Topics: Animals; Base Sequence; Cell Compartmentation; Cell Line; Cell Membrane; DNA; DNA Mutational Analysis; Enzyme Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Mice; Molecular Sequence Data; Mutation; Myristic Acid; Myristic Acids; Oligonucleotides; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Tyrosine | 1990 |
Mouse Erk-1 gene product is a serine/threonine protein kinase that has the potential to phosphorylate tyrosine.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; Mice; Molecular Sequence Data; Molecular Weight; Myelin Basic Protein; Oligonucleotides; Phosphoprotein Phosphatases; Phosphoproteins; Phosphotyrosine; Polymerase Chain Reaction; Protein Kinases; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Recombinant Proteins; Tyrosine | 1991 |
Mutational analysis of repression and activation of the tyrP gene in Escherichia coli.
Topics: Carrier Proteins; Deoxyribonuclease I; DNA Mutational Analysis; Escherichia coli; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Oligonucleotides; Operator Regions, Genetic; Phenylalanine; Promoter Regions, Genetic; Tyrosine | 1991 |
Recombinant human fibrinogen and sulfation of the gamma' chain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cricetinae; Fibrinogen; Genetic Vectors; Humans; Molecular Sequence Data; Molecular Weight; Oligonucleotides; Recombinant Proteins; Sulfates; Tyrosine | 1991 |
Presence of hormonogenic and repetitive domains in the first 930 amino acids of bovine thyroglobulin as deduced from the cDNA sequence.
Topics: Amino Acids; Animals; Base Sequence; Cattle; Chemical Phenomena; Chemistry; Cloning, Molecular; Codon; Dinucleoside Phosphates; DNA; Glycosides; Nucleotides; Oligonucleotides; Peptides; Protein Sorting Signals; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Thyroglobulin; Tyrosine | 1985 |
Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus.
Topics: Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Drosophila melanogaster; Genes; Histidine; Metamorphosis, Biological; Models, Biological; Mutation; Oligonucleotides; Ribonucleotides; RNA, Transfer; Spectrophotometry, Ultraviolet; Transcription, Genetic; Tritium; Tyrosine | 1973 |
Partial degradation of transfer RNAs and transfer RNA fragments by spleen phosphodiesterase as studied by disc electrophoretic methods.
Topics: Animals; Base Sequence; Chemical Phenomena; Chemistry; Densitometry; Electrophoresis, Disc; Escherichia coli; Kinetics; Methods; Oligonucleotides; Phenylalanine; Phosphoric Acids; Phosphoric Diester Hydrolases; RNA, Bacterial; RNA, Transfer; Serine; Spleen; Swine; Tyrosine | 1972 |
Partial degradation of transfer RNAs by sheep kidney nuclease.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Animals; Coliphages; Cytosine Nucleotides; Electrophoresis, Disc; Escherichia coli; Kidney; Kinetics; Magnesium; Oligonucleotides; Phenylalanine; Phosphoric Diester Hydrolases; Polynucleotides; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Serine; Sheep; Snakes; Tyrosine; Uracil Nucleotides; Valine; Venoms | 1972 |
Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient tRNA.
Topics: Base Sequence; Chromatography, DEAE-Cellulose; Chromatography, Paper; Culture Media; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Escherichia coli; Galactosidases; Methyltransferases; Mutation; Oligonucleotides; Phosphoric Diester Hydrolases; Phosphorus Isotopes; Ribonucleotides; Ribose; RNA, Bacterial; RNA, Transfer; Thymine Nucleotides; Transduction, Genetic; Tritium; Tyrosine; Venoms | 1973 |
Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Base Sequence; Binding Sites; Deoxyribonucleotides; Diphosphates; Escherichia coli; Kinetics; Leucine; Lysine; Oligonucleotides; Phenylalanine; Phosphorus Radioisotopes; Proline; Protein Binding; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Time Factors; Tritium; Tyrosine | 1974 |
Structural studies on a tyrosine tRNA precursor.
Topics: Adenine Nucleotides; Autoradiography; Base Sequence; Carbodiimides; Cytosine Nucleotides; Electrophoresis; Guanine Nucleotides; Hydrolysis; Hydroxylamines; Mutation; Nucleic Acid Conformation; Oligonucleotides; Phosphorus Radioisotopes; Polynucleotides; Ribonucleases; RNA, Transfer; Tyrosine; Uracil Nucleotides | 1973 |
Effect of increasing chain length of AA-oligonucleotide acceptors on their reactivity at the peptidyl transferase center in ribosomes and polysomes.
Topics: Acetyltransferases; Amino Acids; Binding Sites; Carbon Isotopes; Cytoplasm; Escherichia coli; Genetic Code; Kinetics; Nucleotides; Oligonucleotides; Peptide Chain Elongation, Translational; Peptides; Phenylalanine; Polyribosomes; Protein Conformation; Ribonucleases; Ribosomes; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Tritium; Tyrosine | 1972 |
Amino acid acceptor stem of E. coli suppressor tRNA tyr is a site of synthetase recognition.
Topics: Alleles; Amino Acids; Amino Acyl-tRNA Synthetases; Base Sequence; Binding Sites; Carbon Isotopes; Coliphages; Electrophoresis; Escherichia coli; Genetic Code; Glutamine; Lysogeny; Mutation; Oligonucleotides; Phenylalanine; RNA, Transfer; Suppression, Genetic; Transduction, Genetic; Tyrosine | 1973 |
High-resolution NMR investigation of base pairing structure of transfer RNA.
Topics: Arginine; Base Sequence; Binding Sites; Chromatography, Gel; Escherichia coli; Glutamates; Hot Temperature; Magnetic Resonance Spectroscopy; Methionine; Nucleic Acid Conformation; Oligonucleotides; Phenylalanine; Ribonucleases; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine | 1973 |
Effects of the ionic environment on modification of yeast tyrosine transfer ribonucleic acid with N-acetoxy-2-acetylaminofluorene.
Topics: Acetamides; Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Fluorenes; Guanosine; Kinetics; Liver; Magnesium; Models, Chemical; Oligonucleotides; Osmolar Concentration; Pancreas; Potassium; Rats; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Transfer RNA Aminoacylation; Tyrosine; Uridine | 1974 |
Current work on the synthesis of transfer RNA genes.
Topics: Base Sequence; Chromosome Mapping; DNA-Directed RNA Polymerases; Escherichia coli; Genes; Genetic Code; Oligonucleotides; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Ribonucleotides; RNA, Bacterial; RNA, Transfer; Structure-Activity Relationship; Suppression, Genetic; Transcription, Genetic; Tyrosine | 1973 |
Nucleotide sequence in the promoter region of the Escherichia coli tyrosine tRNA gene.
Topics: Base Sequence; Chromatography, Gel; DNA Nucleotidyltransferases; DNA, Bacterial; Escherichia coli; Genetic Code; Nucleic Acid Hybridization; Oligonucleotides; Operon; Polynucleotides; RNA, Transfer; Transcription, Genetic; Tyrosine | 1974 |
Studies on polynucleotides. CXXII. The dodecanucleotide sequence adjoining the C-C-A end of the tyrosine transfer ribonucleic acid gene.
Topics: Adenine Nucleotides; Base Sequence; Coliphages; Cytosine Nucleotides; Deoxyribonucleotides; DNA Nucleotidyltransferases; DNA Repair; DNA, Viral; Genes; Genetic Code; Kinetics; Nucleic Acid Renaturation; Nucleosides; Nucleotides; Oligonucleotides; Phosphorus Isotopes; Polynucleotides; RNA, Transfer; Templates, Genetic; Transduction, Genetic; Tritium; Tyrosine | 1973 |
Cell-free synthesis of SU + 3 tyrosyl transfer RNA: characterization of the 4S product.
Topics: Base Sequence; Cell-Free System; Chromatography, DEAE-Cellulose; Coliphages; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Oligonucleotides; Phosphorus Isotopes; Ribonucleotides; RNA, Transfer; RNA, Viral; Transcription, Genetic; Tyrosine | 1973 |
Gene A protein of bacteriophage phi X174 is a highly specific single-strand nuclease and binds via a tyrosyl residue to DNA after cleavage.
Topics: Bacteriophage phi X 174; Binding Sites; DNA, Viral; Endonucleases; Oligonucleotides; Substrate Specificity; Tyrosine; Viral Proteins | 1984 |
Lambda phage cro repressor. Non-specific DNA binding.
Topics: Bacteriophage lambda; Base Composition; Binding Sites; DNA, Viral; Genes, Regulator; Genes, Viral; Nucleic Acid Conformation; Oligonucleotides; Osmolar Concentration; Spectrometry, Fluorescence; Tyrosine | 1982 |
Genome-linked protein VPg of poliovirus is present as free VPg and VPg-pUpU in poliovirus-infected cells.
Topics: Genes, Viral; HeLa Cells; Humans; Molecular Weight; Oligonucleotides; Oligoribonucleotides; Poliovirus; Tyrosine; Viral Core Proteins; Viral Proteins | 1983 |
[Analogs of human proinsulin. Obtaining a deletion at the site of the proinsulin gene encoding the region of receptor binding].
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Escherichia coli; Gene Deletion; Genetic Code; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Proinsulin; Receptor, Insulin; Recombinant Proteins; Tyrosine | 1994 |
The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cricetinae; ErbB Receptors; GRB2 Adaptor Protein; Humans; Insulin; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Oligonucleotides; Oncogene Protein p21(ras); Phosphoproteins; Phosphorylation; Proteins; Signal Transduction; Tyrosine | 1993 |
An oligonucleotide inhibits oligomerization of a rolling circle initiator protein at the pT181 origin of replication.
Topics: Bacterial Proteins; Base Sequence; Centrifugation, Density Gradient; Dimerization; DNA Replication; DNA-Binding Proteins; DNA, Bacterial; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Plasmids; Replication Origin; Tyrosine | 1998 |
Raman and CD spectroscopy of recombinant 68-kDa DNA human topoisomerase I and its complex with suicide DNA-substrate.
Topics: Algorithms; Amino Acid Sequence; Circular Dichroism; Disulfides; DNA Topoisomerases, Type I; Humans; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Oligonucleotides; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectrum Analysis, Raman; Substrate Specificity; Tryptophan; Tyrosine | 1998 |
Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells.
Topics: Antibodies, Monoclonal; Binding Sites; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Line; DNA; DNA-Binding Proteins; Enterotoxins; Epitopes, T-Lymphocyte; Humans; Interleukin-2; Oligonucleotides; Phosphorylation; Promoter Regions, Genetic; Receptors, Antigen, T-Cell; Signal Transduction; Staphylococcus aureus; STAT3 Transcription Factor; Superantigens; Trans-Activators; Tyrosine | 1999 |
Reverse gyrase, the two domains intimately cooperate to promote positive supercoiling.
Topics: Adenosine Triphosphate; Binding Sites; Catalysis; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Dose-Response Relationship, Drug; Escherichia coli; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Silver Staining; Sodium Chloride; Sulfolobus acidocaldarius; Temperature; Tyrosine | 2000 |
Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma -induced differentiation of myeloid leukemia cell lines.
Topics: Binding Sites; Blotting, Northern; Blotting, Western; Cell Differentiation; DNA; DNA-Binding Proteins; DNA, Complementary; Genes, Reporter; Homeobox A10 Proteins; Homeodomain Proteins; Humans; Interferon-gamma; Leukemia, Myeloid; Membrane Glycoproteins; Mutagenesis, Site-Directed; NADPH Oxidase 2; NADPH Oxidases; Oligonucleotides; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine; U937 Cells | 2000 |
Synthesis and purification of horseradish peroxidase-labeled oligonucleotides for tyramide-based fluorescence in situ hybridization.
Topics: Chromatography, Gel; Chromosomes, Human; DNA, Ribosomal; Fluorescent Dyes; Horseradish Peroxidase; Humans; In Situ Hybridization, Fluorescence; Male; Oligonucleotide Probes; Oligonucleotides; Tyrosine | 2000 |
In vitro selection of RNA aptamers.
Topics: Base Sequence; Cellulose; Cloning, Molecular; Gene Deletion; Gene Products, rex; Genetic Techniques; Humans; Models, Genetic; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotides; Point Mutation; Polymerase Chain Reaction; Protein Tyrosine Phosphatases; RNA; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Temperature; Transcription, Genetic; Tyrosine | 2000 |
Ff gene 5 protein has a high binding affinity for single-stranded phosphorothioate DNA.
Topics: Circular Dichroism; DNA, Single-Stranded; DNA, Viral; Inovirus; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphates; Phenylalanine; Poly A; Protein Binding; Salts; Sodium Chloride; Thionucleotides; Titrimetry; Tyrosine; Viral Proteins | 2001 |
In vitro selection of DNA aptamers that bind L-tyrosinamide.
Topics: Base Sequence; Chromatography, Affinity; Combinatorial Chemistry Techniques; DNA Topoisomerases, Type I; DNA, Single-Stranded; Drug Design; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Genetic Techniques; Molecular Sequence Data; Molecular Structure; Oligodeoxyribonucleotides; Oligonucleotides; Phenylalanine; Polymerase Chain Reaction; RNA; Sequence Alignment; Sequence Analysis, DNA; Stereoisomerism; Taq Polymerase; Topoisomerase I Inhibitors; Tyrosine | 2001 |
Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences.
Topics: Blotting, Western; Electrophoresis, Polyacrylamide Gel; Glioblastoma; Glioma; Humans; Immunohistochemistry; Oligonucleotides; Peroxynitrous Acid; Protein Processing, Post-Translational; Recombinant Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyrosine | 2001 |
Advanced glycation end product-induced proliferation in NRK-49F cells is dependent on the JAK2/STAT5 pathway and cyclin D1.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Glycation End Products, Advanced; Janus Kinase 2; Milk Proteins; Oligonucleotides; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; STAT5 Transcription Factor; Time Factors; Trans-Activators; Tyrosine | 2001 |
Effects of mutations at tyrosine 66 and asparagine 123 in the active site pocket of Escherichia coli uracil DNA glycosylase on uracil excision from synthetic DNA oligomers: evidence for the occurrence of long-range interactions between the enzyme and subs
Topics: Asparagine; Binding Sites; DNA Glycosylases; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genotype; Humans; Mutation; N-Glycosyl Hydrolases; Oligonucleotides; Protein Binding; Substrate Specificity; Tyrosine; Uracil; Uracil-DNA Glycosidase; Viral Proteins | 2002 |
SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells.
Topics: Animals; Blotting, Western; Cell Differentiation; DNA; DNA, Complementary; Genes, Reporter; Glutathione Transferase; Glycoproteins; Helminth Proteins; Homeobox A10 Proteins; Homeodomain Proteins; Humans; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mutagenesis; NADPH Oxidase 2; NADPH Oxidases; Oligonucleotides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plasmids; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Time Factors; Transcription, Genetic; Transfection; Tyrosine; U937 Cells | 2002 |
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4.
Topics: Animals; Blotting, Western; Cell Line; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Genetic Vectors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Interferon-alpha; Interleukin-12; Killer Cells, Natural; Luciferases; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Inhibitors of Activated STAT; Protein Isoforms; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Signal Transduction; STAT4 Transcription Factor; T-Lymphocytes; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tyrosine | 2003 |
Characterization of a myeloid tyrosine phosphatase, Lyp, and its role in the Bcr-Abl signal transduction pathway.
Topics: Agar; Animals; Blotting, Western; Cloning, Molecular; COS Cells; Cytosol; DNA, Complementary; Fusion Proteins, bcr-abl; HL-60 Cells; Humans; K562 Cells; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine | 2003 |
Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; COS Cells; Cysteine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Genes, Reporter; Humans; Isoleucine; Kinetics; Ligands; Mesylates; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Sequence Homology, Amino Acid; Transfection; Tyrosine; Water | 2003 |
Interleukin 1 (IL-1) induces the activation of Stat3.
Topics: Base Sequence; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Interleukin-1; Molecular Sequence Data; Oligonucleotides; Phosphorylation; Serine; STAT3 Transcription Factor; Trans-Activators; Tyrosine | 2003 |
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.
Topics: Alanine; Binding Sites; Camptothecin; Catalysis; Cell Survival; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Humans; Ions; Kinetics; Models, Molecular; Mutation; Oligonucleotides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Time Factors; Tyrosine | 2003 |
Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease.
Topics: Actins; Blotting, Western; Calcium; Calpain; Cell Line, Tumor; Cell Nucleus; Genome; Humans; I-kappa B Proteins; Immunoblotting; Luciferases; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Oligonucleotides; Oxidative Stress; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Transfection; Tyrosine; Viral Nonstructural Proteins | 2003 |
VALINE OLIGONUCLEOTIDE COMPLEXES PRODUCED BY T1-RIBONUCLEASE FROM VALINE-ACCEPTOR RIBONUCLEIC ACID.
Topics: Biochemical Phenomena; Biochemistry; Leucine; Oligonucleotides; Phenylalanine; Polynucleotides; Research; Ribonuclease T1; Ribonucleases; RNA; Tritium; Tyrosine; Valine | 1964 |
DETERMINATION OF NUCLEOTIDE SEQUENCES IN S-RNA. 3. ISOLATION OF OLIGONUCLEOTIDES FROM THE ACCEPTOR END OF AMINO ACID-SPECIFIC ACCEPTOR CHAINS OF SOLUBLE RIBONUCLEIC ACID.
Topics: Amino Acids; Ammonium Compounds; Base Sequence; Carbon Isotopes; Chromatography; Dialysis; Electrophoresis; Leucine; Metabolism; Nucleosides; Nucleotides; Oligonucleotides; Phenylalanine; Quaternary Ammonium Compounds; Renal Dialysis; Research; Ribonucleases; RNA; Tritium; Tyrosine; Valine; Yeasts | 1964 |
GIT1 mediates Src-dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Angiotensin II; Animals; Calcium; Cell Cycle Proteins; Cell Line; Cells, Cultured; Cloning, Molecular; DNA Mutational Analysis; Enzyme Activation; Epidermal Growth Factor; Gene Deletion; GTPase-Activating Proteins; Humans; Immunoblotting; Mass Spectrometry; Models, Biological; Models, Genetic; Molecular Sequence Data; Muscle, Smooth; Oligonucleotides; Peptides; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Signal Transduction; src-Family Kinases; Transfection; Type C Phospholipases; Tyrosine | 2003 |
Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Blotting, Western; Breast Neoplasms; Cell Division; Cell Line, Tumor; Culture Media, Serum-Free; Enzyme Inhibitors; Flavonoids; GRB2 Adaptor Protein; Humans; Insulin-Like Growth Factor I; Ligands; MAP Kinase Signaling System; Oligonucleotides; Oligonucleotides, Antisense; Phosphorylation; Precipitin Tests; Prognosis; Protein Binding; Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptor, ErbB-2; Receptor, IGF Type 1; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Trastuzumab; Tyrosine | 2004 |
Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia.
Topics: Amino Acid Motifs; Antigens, CD; Antigens, Neoplasm; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Epithelium; Fibrinolysin; Gene Library; Glycoproteins; Green Fluorescent Proteins; Heparin; Humans; Keratinocytes; Luminescent Proteins; Mass Spectrometry; Membrane Glycoproteins; Models, Biological; Molecular Sequence Data; Neoplasm Proteins; Oligonucleotides; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Structure, Tertiary; Receptors, Interleukin-6; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Trypsin; Tyrosine | 2004 |
Insight into mutation-induced activation of the luteinizing hormone receptor: molecular simulations predict the functional behavior of engineered mutants at M398.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Cell Line; Cyclic AMP; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Conformation; Receptors, LH; Rhodopsin; Sequence Homology, Amino Acid; Software; Time Factors; Transfection; Tyrosine | 2004 |
DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.
Topics: Amino Acids; Aspartic Acid; Base Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; DNA; Electrophoretic Mobility Shift Assay; Glutathione; Indicators and Reagents; Monocrotaline; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Tyrosine | 2004 |
Cortactin associates with N-cadherin adhesions and mediates intercellular adhesion strengthening in fibroblasts.
Topics: Actins; Animals; Cadherins; Cell Adhesion; Cell Line; Cell Survival; Cortactin; Cytoskeletal Proteins; Cytoskeleton; Fibroblasts; Flow Cytometry; Green Fluorescent Proteins; Immunoblotting; Immunoprecipitation; Microfilament Proteins; Microscopy, Fluorescence; Microscopy, Video; Models, Biological; Oligonucleotides; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Time Factors; Transfection; Tyrosine | 2004 |
Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis.
Topics: Amino Acid Sequence; Animals; Binding Sites; COS Cells; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Kinetics; Ligands; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Tyrosine | 2004 |
Identification of residues within UvrB that are important for efficient DNA binding and damage processing.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Bacillus; Base Sequence; Binding Sites; Cholesterol; DNA; DNA Damage; DNA Helicases; DNA Repair; Escherichia coli Proteins; Glutamic Acid; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Tyrosine | 2004 |
Functional relevance of the conserved DNA-binding domain of STAT2.
Topics: Cell Nucleus; Cell Proliferation; Chromatin; Chromatin Immunoprecipitation; Conserved Sequence; Dimerization; DNA; DNA-Binding Proteins; DNA, Complementary; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Interferons; Luciferases; Models, Molecular; Mutagenesis; Mutation; Oligonucleotides; Protein Binding; Protein Structure, Tertiary; RNA; STAT2 Transcription Factor; Time Factors; Trans-Activators; Transcriptional Activation; Transfection; Tyrosine | 2005 |
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids.
Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Collagen; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Liver; Liver Neoplasms; Male; Microcirculation; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Oligonucleotides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Tyrosine | 2005 |
Escherichia coli single-strand binding protein-DNA interactions on carbon nanotube-modified electrodes from a label-free electrochemical hybridization sensor.
Topics: Base Sequence; Biosensing Techniques; DNA-Binding Proteins; DNA, Single-Stranded; Electrochemistry; Electrodes; Escherichia coli; Guanine; Mutation; Nanotubes, Carbon; Nucleic Acid Hybridization; Oligonucleotides; Oxidation-Reduction; Tryptophan; Tyrosine | 2005 |
Integron cassette insertion: a recombination process involving a folded single strand substrate.
Topics: Attachment Sites, Microbiological; Base Sequence; Binding Sites; Catalysis; Drug Resistance; Escherichia coli; Integrases; Integrons; Models, Genetic; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oligonucleotides; Plasmids; Polymerase Chain Reaction; Protein Binding; Recombination, Genetic; Sequence Homology, Nucleic Acid; Tyrosine | 2005 |
Probing the adhesive footprints of Mytilus californianus byssus.
Topics: Acetic Acid; Amino Acid Sequence; Animals; Arginine; Asparagine; Bivalvia; Cell Adhesion; Cloning, Molecular; DNA Primers; DNA, Complementary; Electrophoresis; Genetic Variation; Glycine; Isoelectric Point; Models, Chemical; Molecular Sequence Data; Mytilus; Oligonucleotides; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2006 |
CpG DNA enhances macrophage cell spreading by promoting the Src-family kinase-mediated phosphorylation of paxillin.
Topics: Animals; Binding Sites; Blotting, Western; Cell Line; Cell Movement; Cells, Cultured; CpG Islands; Female; Humans; Immunoprecipitation; Macrophages; Mice; Mice, Inbred C57BL; Oligonucleotides; Paxillin; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins c-hck; src Homology Domains; src-Family Kinases; Tyrosine | 2006 |
Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; Down-Regulation; Drug Resistance, Neoplasm; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotides; Phosphorylation; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase.
Topics: 2-Aminopurine; Base Sequence; DNA; DNA Topoisomerases, Type I; Guanine; Indoles; Models, Molecular; Molecular Sequence Data; Oligonucleotides; Protein Binding; Recombinant Proteins; Toluene; Tyrosine; Vaccinia virus | 2006 |
WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups.
Topics: Cells, Cultured; DNA; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Exodeoxyribonucleases; Genes, p53; Glycolates; Humans; Oligonucleotides; Oxidation-Reduction; Proteins; Reactive Oxygen Species; Recombinant Proteins; RecQ Helicases; Tyrosine; Werner Syndrome Helicase | 2007 |
Nuclear factor-kappaB activation via tyrosine phosphorylation of inhibitor kappaB-alpha is crucial for ciliary neurotrophic factor-promoted neurite growth from developing neurons.
Topics: Animals; Animals, Newborn; Cells, Cultured; Ciliary Neurotrophic Factor; Enzyme Activation; I-kappa B Proteins; Intracellular Signaling Peptides and Proteins; Mice; Neurites; Neurons, Afferent; NF-kappa B; NF-KappaB Inhibitor alpha; Nodose Ganglion; Oligonucleotides; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; Transcription, Genetic; Tyrosine | 2007 |
Oligo(tyrosine sulfate)s as heparin pentasaccharide mimic: evaluation by surface noncovalent affinity mass spectrometry.
Topics: Antithrombin III; Blood Coagulation Factors; Heparitin Sulfate; Humans; Mass Spectrometry; Molecular Mimicry; Oligonucleotides; Protein Binding; Ribosomal Proteins; RNA-Binding Proteins; Structure-Activity Relationship; Tyrosine | 2008 |
High glucose-induced NF-kappaB activation occurs via tyrosine phosphorylation of IkappaBalpha in human glomerular endothelial cells: involvement of Syk tyrosine kinase.
Topics: Antioxidants; Biotransformation; Blotting, Western; Cell Line; Chemokine CCL2; Electrophoretic Mobility Shift Assay; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Glucose; Humans; Immunohistochemistry; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; NF-kappa B; Oligonucleotides; Phosphorylation; Protein-Tyrosine Kinases; Reactive Oxygen Species; RNA, Small Interfering; Syk Kinase; Thioctic Acid; Transfection; Tyrosine | 2008 |
Myosin IIC: a third molecular motor driving neuronal dynamics.
Topics: Animals; Cell Line, Tumor; Humans; Mice; Microscopy, Fluorescence; Models, Biological; Myosin Type II; Neurites; Neurons; Nonmuscle Myosin Type IIA; Nonmuscle Myosin Type IIB; Oligonucleotides; Phenotype; Protein Isoforms; Tyrosine | 2008 |
Human serum albumin as a catalyst of RNA cleavage: N-homocysteinylation and N-phosphorylation by oligonucleotide affinity reagent alter the reactivity of the protein.
Topics: Catalysis; Electrophoresis, Polyacrylamide Gel; Homocysteine; Humans; Hydrolysis; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Statistical; Oligonucleotides; Phosphorylation; RNA; Serum Albumin; Tyrosine | 2008 |
Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.
Topics: Blotting, Western; Cell Line, Tumor; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Humans; Immunoprecipitation; Interleukin-2; Janus Kinase 3; Lymphocytes; Oligonucleotides; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Phosphatase 1; Protein Phosphatase 2; Receptors, Interleukin-2; Serine; STAT5 Transcription Factor; Tumor Suppressor Proteins; Tyrosine | 2010 |
Relaxase DNA binding and cleavage are two distinguishable steps in conjugative DNA processing that involve different sequence elements of the nic site.
Topics: Base Sequence; Binding Sites; Crystallography, X-Ray; DNA; DNA Nucleotidyltransferases; DNA, Single-Stranded; DNA, Superhelical; Escherichia coli; Escherichia coli Proteins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Plasmids; Tyrosine | 2010 |
Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase.
Topics: Amino Acids; Crystallography, X-Ray; DNA; DNA Damage; DNA Primers; DNA Repair; DNA-Directed DNA Polymerase; Kinetics; Models, Biological; Mutagenesis; Mutation; Nucleotides; Oligonucleotides; Thermus; Tyrosine | 2012 |
Redox modulation of flavin and tyrosine determines photoinduced proton-coupled electron transfer and photoactivation of BLUF photoreceptors.
Topics: Amino Acid Sequence; Crystallography, X-Ray; Electron Transport; Escherichia coli; Flavins; Kinetics; Light; Molecular Conformation; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Oxidation-Reduction; Photochemistry; Photoreceptors, Microbial; Spectrophotometry; Synechocystis; Tyrosine | 2012 |
The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Bone Morphogenetic Protein Receptors, Type II; Carotid Stenosis; Chemokine CCL2; DEAD-box RNA Helicases; Disease Progression; Gene Expression Regulation; Interleukin-6; Macrophage Activation; Macrophages; Mice; Mice, Knockout; MicroRNAs; Nitric Oxide Synthase Type II; Oligonucleotides; Proto-Oncogene Proteins c-akt; Ribonuclease III; RNA, Antisense; Signal Transduction; Tyrosine; Up-Regulation; Vasculitis | 2013 |
DNA catalysts with tyrosine kinase activity.
Topics: DNA, Catalytic; Guanosine Triphosphate; Oligonucleotides; Phosphorylation; Protein-Tyrosine Kinases; RNA; Tyrosine | 2013 |
Rational design of a redox-labeled chiral target for an enantioselective aptamer-based electrochemical binding assay.
Topics: Aptamers, Nucleotide; Binding, Competitive; Diffusion; Electrochemistry; Electrophoresis, Capillary; Oligonucleotides; Oxidation-Reduction; Stereoisomerism; Tyrosine | 2014 |
Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites.
Topics: Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Eye Proteins; Fibroblast Growth Factors; Gene Expression Profiling; Gene Expression Regulation, Developmental; Homeodomain Proteins; Lens, Crystalline; Mutation; Oligonucleotides; Paired Box Transcription Factors; PAX6 Transcription Factor; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Repressor Proteins; Signal Transduction; Tyrosine; Xenopus laevis; Xenopus Proteins | 2015 |
The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
Topics: Bone Density Conservation Agents; Catalysis; Catalytic Domain; Crystallization; Diphosphonates; Drug Evaluation, Preclinical; Geranyltranstransferase; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Imidazoles; Inhibitory Concentration 50; Molecular Conformation; Mutation; Nitrogen; Oligonucleotides; Protein Binding; Recombinant Proteins; Threonine; Tyrosine; Zoledronic Acid | 2015 |
Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase.
Topics: Amino Acid Substitution; Arginine; Benzothiazoles; Biological Assay; Cloning, Molecular; Diamines; DNA Primase; DNA Primers; DNA-Directed DNA Polymerase; Escherichia coli; Fluorescent Dyes; Fluorometry; Gene Expression; Gene Library; Humans; Multifunctional Enzymes; Mutation; Oligonucleotides; Organic Chemicals; Protein Binding; Protein Engineering; Protein Multimerization; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA-Directed DNA Polymerase; Tyrosine | 2017 |
Nitration of tyrosine and its effect on DNA hybridization.
Topics: Biosensing Techniques; DNA, Single-Stranded; Electrochemistry; Nitro Compounds; Nucleic Acid Hybridization; Oligonucleotides; Oxidation-Reduction; Tyrosine | 2018 |
Toxoplasma gondii stabilises tetrameric complexes of tyrosine-phosphorylated signal transducer and activator of transcription-1 and leads to its sustained and promiscuous DNA binding.
Topics: Animals; Cell Nucleus; DNA; Host-Parasite Interactions; Interferon-gamma; Mice; Oligonucleotides; Phosphorylation; Protein Multimerization; Protozoan Proteins; RAW 264.7 Cells; Serine; STAT1 Transcription Factor; Toxoplasma; Toxoplasmosis; Tyrosine | 2018 |