tyrosine has been researched along with nadp in 116 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (31.90) | 18.7374 |
| 1990's | 25 (21.55) | 18.2507 |
| 2000's | 38 (32.76) | 29.6817 |
| 2010's | 15 (12.93) | 24.3611 |
| 2020's | 1 (0.86) | 2.80 |
| Authors | Studies |
|---|---|
| Baron, AJ; Brett, M; Fincham, JR; Seale, TW | 1 |
| Birdsall, B; Burgen, AS; Feeney, J; Griffiths, DV; Kimber, BJ; King, RW; Roberts, GC; Scudder, P | 1 |
| Blakley, ER | 1 |
| Archakov, AI; Bachmanova, GI; Izotov, MV; Karuzina, II; Kuznetsova, GP | 1 |
| DeGroot, LJ; Yamamoto, K | 2 |
| Conn, EE; Lees, EM; MacFarlane, IJ | 1 |
| Blumenthal, KM; Smith, EL | 1 |
| Cui, K; Lu, AY; Ma, Q; Xiao, F; Yang, CS | 1 |
| Jellinck, PH; McLachlan, JA; Newbold, RR | 1 |
| Downey, GP; Grinstein, S; Pâquet, MR; Trudel, S | 1 |
| Grinstein, S; Pâquet, MR; Trudel, S | 1 |
| Kasper, CB; Porter, TD; Shen, AL; Wilson, TE | 1 |
| Birdsall, B; Feeney, J; Hammond, SJ; Roberts, GC; Searle, MS | 1 |
| Jekel, PA; Müller, F; Schreuder, HA; van Berkel, WJ; Weijer, WJ; Wierenga, RK | 1 |
| Benkovic, SJ; Chen, JT; Taira, K; Tu, CP | 1 |
| Eliasson, R; Jörnvall, H; Reichard, P | 1 |
| Aki, K; Maeda-Yorita, K | 1 |
| DeGroot, LJ; Hati, R; Liu, C; Nagasaka, A | 1 |
| Fisher, DB; Kaufman, S | 1 |
| Stone, KJ; Townsley, BH | 1 |
| DeGroot, LJ; Hati, RN | 1 |
| Colman, RF | 1 |
| Benoiton, NL; D'lorio, A; Sharma, S; Tong, JH | 1 |
| Levine, RJ; Lovenberg, W; Sjoerdsma, A | 1 |
| Matsuzaki, S; Suzuki, M | 1 |
| Abbassi, V; Bastomsky, CH; McKenzie, JM | 1 |
| Burke, G | 1 |
| Kaufman, S | 1 |
| Benoiton, NL; D'Iorio, A; Tong, JH | 1 |
| Picco, C; Pontremoli, S; Rippa, M; Signorini, M | 1 |
| Friedrich, B; Schlegel, HG | 1 |
| Degroot, LJ; Hati, R; Nagasaka, A; Niepomniszcze, H | 1 |
| Pontremoli, S; Rippa, M; Signorini, M | 1 |
| Scisłowski, PW; Słominski, A | 1 |
| Dunlap, RB; Rosson, D | 1 |
| Kaufman, S; Matthews, RG | 1 |
| Keller, B; Keller, E; Lingens, F; Salcher, O | 1 |
| Hösel, W; Nahrstedt, A | 1 |
| Miyazaki, K; Oshima, T; Yaoi, T | 1 |
| Chatterjee, IB; Mukhopadhyay, CK | 1 |
| Borhani, DW; Petrash, JM; Quiocho, FA; Tarle, I; Wilson, DK | 1 |
| Bradley, M; Cummings, RT; Pickett, M; Rennex, D; Walsh, CT | 1 |
| Covès, J; Eschenbrenner, M; Fontecave, M; Nivière, V | 1 |
| Du, L; Halkier, BA; Lykkesfeldt, J; Olsen, CE | 1 |
| Benson, TE; Hogle, JM; Walsh, CT | 1 |
| Breton, R; Fontecilla-Camps, JC; Housset, D; Mazza, C | 1 |
| Dallner, G; Ernster, L; Forsmark-Andrée, P; Persson, B; Radi, R | 1 |
| Baldwin, J; Francescutti, D; Lee, L; Mutus, B | 1 |
| Broger, C; D'Arcy, A; Dale, GE; DeHoogt, R; Hartman, PG; Jolidon, S; Kompis, I; Labhardt, AM; Langen, H; Locher, H; Oefner, C; Page, MG; Stüber, D; Then, RL; Wipf, B | 1 |
| Baylor, KJ; Heffron, JJ; McIntosh, J; Shine, CM | 1 |
| Bizouarn, T; Diggle, C; Grimley, R; Jackson, JB; Thomas, CM | 1 |
| Braunstein, LD; Pang, J; Stanton, RC; Stuhlmeier, KM; Tian, WN; Tian, X; Xi, QC | 1 |
| Penning, TM; Ratnam, K; Schlegel, BP | 1 |
| Arscott, LD; Krauth-Siegel, RL; Schirmer, RH; Schönleben-Janas, A; Williams, CH | 1 |
| Crowley, JR; Hollenberg, PF; Lin, Hl; Osawa, Y; Roberts, ES; Vuletich, JL | 1 |
| Capeillère-Blandin, C | 1 |
| Ariño, A; Feyereisen, R; Guzov, VM; Murataliev, MB | 1 |
| Aliverti, A; Arakaki, AK; Calcaterra, NB; Carrillo, N; Ceccarelli, EA; Deng, Z; Karplus, PA; Orellano, EG; Ottado, J; Zanetti, G | 1 |
| Kanadia, RN; Kuo, WN; Shanbhag, VP; Toro, R | 1 |
| Arvai, AS; Bourne, Y; Putnam, CD; Tainer, JA | 1 |
| Aliverti, A; Arakaki, AK; Carrillo, N; Ceccarelli, EA; Karplus, PA; Piubelli, L; Zanetti, G | 1 |
| Dou, Y; Gardner, AM; Gardner, PR; Martin, LA; Olson, JS | 1 |
| Beernink, PT; Doyle, SA; Koshland, DE | 1 |
| Flynn, TG; Green, NC; Hyndman, D; Jia, Z; Li, L; Ye, Q | 1 |
| Jeong, EY; Kim, IS; Lee, H; Sopher, C | 1 |
| Arakaki, AK; Calcaterra, NB; Ceccarelli, EA; Orellano, EG; Ottado, J | 1 |
| Karginova, O; Lebedev, N; McIvor, W; Timko, MP | 1 |
| Kocis, JM; Kuo, WN; Webb, JK | 1 |
| Gelhaye, E; Jacquot, JP; Rouhier, N | 1 |
| Arruda, P; Castro, GM; de Nucci, G; Langone, F; Martins, ML; Muscará, MN; Papes, F; Rogério, F; Santos, LM; Teixeira, SA | 1 |
| Fang, X; Miller, FJ; Oberley, LW; Oberley, TD; Sharp, WJ; Weintraub, NL | 1 |
| Casaus, JL; De la Rosa, MA; Gómez-Moreno, C; Hervás, M; Lostao, A; Medina, M; Navarro, JA; Sancho, J | 1 |
| Anderson, S; Banta, S; Jarnagin, A; Swanson, BA; Wu, S | 1 |
| Colman, RF; Lee, P | 1 |
| Heyes, DJ; Hunter, CN | 1 |
| Chang, CM; Chen, HJ; Chen, YM | 1 |
| Matringe, M; Rippert, P | 1 |
| Berka, V; Chen, PF; Wu, KK | 1 |
| Ator, MA; Ge, J; Stubbe, J; Yu, G | 1 |
| STANBURY, JB | 1 |
| GAMBORG, OL; SIMPSON, FJ | 1 |
| Ball, BA; Baumber, J; Sabeur, K; Vo, A | 1 |
| Aitken, RJ; Bennetts, L; Lin, M | 1 |
| Leonardi, R; Roach, PL | 1 |
| Kawanishi, S; Murata, M | 1 |
| Hazemann, I; Joachimiak, A; Karplus, M; Mitschler, A; Podjarny, A; Ruiz, F; Schneider, T | 1 |
| Hicks, SN; Howell, EE; Smiley, RD; Stinnett, LG | 1 |
| Frago, S; Gómez-Moreno, C; Martínez-Júlvez, M; Medina, M; Nogués, I; Peregrina, JR; Tejero, J | 1 |
| Hosgood, G; Mirza, MH; Moore, RM; Oliver, JL; Seahorn, TL | 1 |
| Hillson, NJ; Pacholec, M; Walsh, CT | 1 |
| Gómez-Moreno, C; Hermoso, JA; Martínez-Júlvez, M; Maya, C; Medina, M; Pérez-Dorado, I; Sanz-Aparicio, J; Tejero, J | 1 |
| Dumas, R; Ferrer, JL; Legrand, P; Matringe, M; Ravelli, R; Rippert, P; Seux, M | 1 |
| Fujii, A; Jokura, H; Saito, I; Suzuki, A; Tokimitsu, I; Yamamoto, M; Yamamoto, N | 1 |
| Rhee, SG | 1 |
| Chang, GG; Chou, WY; Hsu, YJ; Kuo, CC; Lin, KY; Lin, SY; Lin, YT | 1 |
| Chen, C; Lin, P; Mu, H; Wang, X; Yao, Q | 1 |
| Cha, CI; Cho, YW; Huh, Y; Lee, JJ; Yeo, SG | 1 |
| Borràs, E; Debreczeny, JÉ; Farrés, J; Fita, I; Oppermann, U; Parés, X; Pike, ACW; Porté, S; Shafqat, N; Valencia, E; Yakovtseva, EA | 1 |
| Heyes, DJ; Menon, BR; Scrutton, NS; Waltho, JP | 1 |
| Dhagat, U; El-Kabbani, O; Endo, S; Hara, A; Mamiya, H | 1 |
| Bosc, C; Dale, L; Moutin, MJ; Muller-Steffner, H; Patel, S; Ramakrishnan, L; Schuber, F; Vacquier, VD | 1 |
| Ambrosini, G; Andrisani, A; Armanini, D; Bordin, L; Clari, G; Donà, G; Fiore, C; Fiorentin, D; Frezzato, F; Tibaldi, E | 1 |
| Choi, EM | 1 |
| Aliverti, A; Baroni, S; Pandini, V; Vanoni, MA | 1 |
| Garcia-Viloca, M; González-Lafont, À; Hummer, G; Lans, I; Lluch, JM; Medina, M; Rosta, E | 1 |
| Cai, Y; Cheng, A; Han, X; Lou, H; Sun, Y; Wu, Y; Xu, R; Yu, H | 1 |
| Lingala, Y; Merugu, RT; Vijjulatha, M | 1 |
| Chhabra, A; Deshmukh, MV; Gokhale, RS; Haque, AS; Patel, KD; Sankaranarayanan, R | 1 |
| Naito, H; Nishimura, E; Sakurai, T; Seo, D | 1 |
| Araki, T; Fukuda, Y; Ohshima, T; Sakuraba, H; Shibata, T; Sone, T; Yoneda, K | 1 |
| Chruszcz, M; Demas, M; Grimshaw, S; Hou, J; Minor, W; Osinski, T; Shumilin, IA; Zheng, H; Zimmerman, MD | 1 |
| Kim, HY; Quashie, PK; Shlaifer, I; Turnbull, JL | 1 |
| Gao, H; Li, W; Liang, J; Liu, R; Tao, B; Wang, C; Wang, X; Yang, W; Yang, Z; Zhang, Y | 1 |
| Brian, MS; Edwards, DG; Farquhar, WB; Lennon, SL; Matthews, EL; Patik, JC; Ramick, MG; Seals, DR | 1 |
| Aleksandrov, A; Seo, D; Vos, MH; Zhuang, B | 1 |
1 review(s) available for tyrosine and nadp
| Article | Year |
|---|---|
Mechanism of thyroid hormone formation.
Topics: Animals; Electron Transport Complex IV; Humans; Hydrogen Peroxide; Iodides; Iodine; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Peroxidases; Thyroglobulin; Thyroid Gland; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Tyrosine | 1972 |
1 trial(s) available for tyrosine and nadp
| Article | Year |
|---|---|
Apocynin and Tempol ameliorate dietary sodium-induced declines in cutaneous microvascular function in salt-resistant humans.
Topics: Acetophenones; Adult; Antioxidants; Biomarkers; Blood Flow Velocity; Cyclic N-Oxides; Endothelial Cells; Female; Forearm; Humans; Male; Microcirculation; Middle Aged; NADP; Oxidative Stress; Reactive Oxygen Species; Skin; Sodium Chloride, Dietary; Spin Labels; Time Factors; Tyrosine; Vasodilation; Young Adult | 2019 |
114 other study(ies) available for tyrosine and nadp
| Article | Year |
|---|---|
Amino acid replacements resulting from suppression and missense reversion of a chain-terminator mutation in Neurospora.
Topics: Amino Acid Sequence; Chromosome Mapping; Genes; Genetic Code; Glutamate Dehydrogenase; Leucine; Mutation; NADP; Neurospora; Neurospora crassa; Peptide Chain Termination, Translational; Phenotype; Suppression, Genetic; Tyrosine | 1977 |
19 Fnuclear magnetic resonance studies of ligand binding to 3-fluorotyrosine-and 6-fluorotryptophan-containing dihydrofolate reductase from Lactobacillus casei.
Topics: Binding Sites; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; NADP; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tryptophan; Tyrosine | 1977 |
The catabolism of L-tyrosine by an Arthrobacter sp.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Hydroxyphenylpyruvate Dioxygenase; Arthrobacter; Cell-Free System; NAD; NADP; Oxygenases; Pyruvates; Stereoisomerism; Succinates; Tyrosine; Tyrosine Transaminase | 1977 |
[Comparative study of effects of the tyrosine-copper(II) complex on xenobiotic hydroxylation and lipid peroxidation].
Topics: Animals; Copper; Cytochrome P-450 Enzyme System; Kinetics; Lipid Peroxides; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rats; Superoxide Dismutase; Superoxides; Tyrosine | 1979 |
Participation of NADPH-cytochrome C reductase in thyroid hormone biosynthesis.
Topics: Animals; Antibodies; Catalase; Cattle; Cytochrome c Group; Cytochrome Reductases; Immunodiffusion; In Vitro Techniques; Iodides; Microsomes; Mitochondria; NADP; Peroxidases; Rabbits; Rats; Superoxide Dismutase; Thyroid Gland; Thyroid Hormones; Tyrosine | 1975 |
The in vitro biosynthesis of dhurrin, the cyanogenic glycoside of Sorghum bicolor.
Topics: Aerobiosis; Anaerobiosis; Chromatography, Paper; Glycosides; NADP; Nitriles; Oxidation-Reduction; Plants; Tyrosine; Uridine Diphosphate Glucose | 1975 |
Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora. III. Inactivation by nitration of a tyrosine residue involved in coenzyme binding.
Topics: Amino Acid Sequence; Binding Sites; Glutamate Dehydrogenase; Kinetics; Ligands; Methane; NAD; NADP; Neurospora; Peptide Fragments; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1975 |
Identification of a glycine-rich sequence as an NAD(P)H-binding site and tyrosine 128 as a dicumarol-binding site in rat liver NAD(P)H:quinone oxidoreductase by site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Coenzymes; Consensus Sequence; Cytosol; Dicumarol; Glycine; Kinetics; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD(P)H Dehydrogenase (Quinone); NADP; Oligodeoxyribonucleotides; Protein Binding; Rats; Sequence Alignment; Structure-Activity Relationship; Triazines; Tyrosine | 1992 |
Characteristics of estrogen-induced peroxidase in mouse uterine luminal fluid.
Topics: Animals; Ascorbic Acid; Body Fluids; Chlorophenols; Cytochrome c Group; Diethylstilbestrol; Estradiol; Female; Glutathione; Hydrogen Peroxide; Lactoperoxidase; Mice; NADP; Peroxidase; Superoxide Dismutase; Tritium; Tyrosine; Uterus; Water | 1991 |
Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways.
Topics: Actins; Adenosine Triphosphate; Amanitins; Calcium; Cell Membrane Permeability; Exocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Immunoblotting; Leukemia, Promyelocytic, Acute; Muramidase; NADP; Neutrophils; Oxygen Consumption; Phosphotyrosine; Polymers; Signal Transduction; Thionucleotides; Tumor Cells, Cultured; Tyrosine; Vanadates | 1990 |
Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites.
Topics: Granulocytes; Humans; Leukemia, Prolymphocytic; NADP; Oxygen Consumption; Phosphorylation; Phosphotyrosine; Superoxides; Tumor Cells, Cultured; Tyrosine; Vanadates; Vanadium | 1991 |
Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Catalysis; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA Mutational Analysis; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Kinetics; Molecular Sequence Data; NADH Dehydrogenase; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Rats; Spectrum Analysis; Tyrosine | 1989 |
Dihydrofolate reductase. 1H resonance assignments and coenzyme-induced conformational changes.
Topics: Amino Acid Sequence; Histidine; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Models, Molecular; NADP; Phenylalanine; Protein Conformation; Protons; Tetrahydrofolate Dehydrogenase; Tryptophan; Tyrosine | 1986 |
Chemical modification of tyrosine-38 in p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens by 5'-p-fluorosulfonylbenzoyladenosine: a probe for the elucidation of the NADPH binding site? Involvement in catalysis, assignment in sequence and fitting
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Adenosine; Binding Sites; Catalysis; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Mixed Function Oxygenases; NADP; Protein Conformation; Pseudomonas fluorescens; Tyrosine | 1988 |
Probing the functional role of phenylalanine-31 of Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Amino Acids; Binding Sites; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; Phenylalanine; Plasmids; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1987 |
Superoxide dismutase participates in the enzymatic formation of the tyrosine radical of ribonucleotide reductase from Escherichia coli.
Topics: Enzyme Activation; Escherichia coli; Flavin Mononucleotide; Free Radicals; NADP; Oxygen; Ribonucleotide Reductases; Superoxide Dismutase; Tyrosine | 1986 |
Effect of dinitrophenyl modification on oxidation-reduction of glutathione reductase from yeast.
Topics: Binding Sites; Candida; Circular Dichroism; Dinitrofluorobenzene; Glutathione Reductase; NAD; NADP; Nitrobenzenes; Oxidation-Reduction; Spectrophotometry; Tyrosine | 1985 |
Studies on the biosynthesis of thyroid hormone: reconstruction of a defined in vitro iodinating system.
Topics: Animals; Cattle; Dicumarol; In Vitro Techniques; Iodine; Iodine Isotopes; Iodoproteins; Microsomes; Mitochondria; Monoiodotyrosine; NADP; Oxidoreductases; Peroxidases; Stimulation, Chemical; Thyroid Gland; Thyroid Hormones; Tyrosine; Vitamin K | 1971 |
Tetrahydropterin oxidation without hydroxylation catalyzed by rat liver phenylalanine hydroxylase.
Topics: Animals; Azides; Carbon Isotopes; Catalase; Catalysis; Chymotrypsin; Free Radicals; Hydroxylation; Kinetics; Liver; Lysophosphatidylcholines; NADP; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxidases; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Pyruvates; Rats; Sodium; Stereoisomerism; Tyrosine; Uncoupling Agents | 1973 |
The effect of L-ascorbate on catecholamine biosynthesis.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Catecholamines; Female; Liver; NADP; Oxidation-Reduction; Phenylalanine Hydroxylase; Pteridines; Rats; Time Factors; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1973 |
Function of peroxidase and NADPH cytochrome C reductase during the Wolff-Chaikoff effect.
Topics: Animals; Binding, Competitive; Cytochrome c Group; Cytochrome Reductases; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iodides; Iodine Isotopes; Kinetics; Male; Monoiodotyrosine; NADP; Oxidoreductases; Peroxidases; Protein Binding; Rats; Thyroid Gland; Tyrosine | 1973 |
Studies on the mechanism of iodination supported by thyroidal NADPH-cytochrome c reductase.
Topics: Animals; Carbon Radioisotopes; Cattle; Coloring Agents; Cytochrome c Group; Depression, Chemical; Ferricyanides; Formates; Guaiacol; Heme; In Vitro Techniques; Iodides; Iodine Radioisotopes; Isoproterenol; NADH, NADPH Oxidoreductases; NADP; Potassium; Pyrogallol; Temperature; Thyroid Gland; Trypsin; Tyrosine; Vitamin K | 1973 |
A glutamyl residue in the active site of triphosphopyridine nucleotide-dependent isocitrate dehydrogenase of pig heart.
Topics: Amides; Animals; Aspartic Acid; Binding Sites; Carbodiimides; Carbon Radioisotopes; Carboxy-Lyases; Catalysis; Cysteine; Drug Synergism; Glutamates; Glycine; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Manganese; Morpholines; Myocardium; NADP; Swine; Temperature; Tyrosine | 1973 |
A new biosynthetic pathway to catecholamines via m-tyrosine.
Topics: Adrenal Glands; Animals; Benzyl Compounds; Brain; Carbon Radioisotopes; Catalysis; Catecholamines; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Iron; Liver; Methyldopa; Methyltyrosines; Mice; Monoiodotyrosine; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phosphates; Pterins; Rats; Structure-Activity Relationship; Tyrosine | 1974 |
A tryptophan hydroxylase in cell-free extracts of malignant mouse mast cells.
Topics: 5-Hydroxytryptophan; Animals; In Vitro Techniques; Mast Cells; Mice; Mixed Function Oxygenases; NADP; Neoplasm Transplantation; Pterins; Tyrosine | 1965 |
Deiodination of iodinated amino acids by pig thyroid micrsomes.
Topics: Amino Acids; Amobarbital; Animals; Antimycin A; Chromatography; Electron Transport Complex IV; Hydrogen-Ion Concentration; Iodine; Iodine Isotopes; Microsomes; NAD; NADP; Oxygen; Peroxidases; Swine; Thyroid Gland; Tyrosine | 1967 |
Effect of nicotinamide in vivo on thyroid pyridine nucleotides and radioiodine metabolism.
Topics: Animals; Diiodotyrosine; Iodides; Iodine Isotopes; Iodoproteins; Male; NAD; NADP; Niacinamide; Rats; Stimulation, Chemical; Thyroid Gland; Thyroxine; Triiodothyronine; Tyrosine | 1968 |
Effects of iodotyrosines on basal and stimulated glucose oxidation and phospholipogenesis in sheep thyroid slices.
Topics: Animals; Carbon Dioxide; Diiodotyrosine; Glucose; In Vitro Techniques; Long-Acting Thyroid Stimulator; Monoiodotyrosine; NADP; Phospholipids; Phosphorus Isotopes; Sheep; Stimulation, Chemical; Thyroid Gland; Thyrotropin; Tyrosine | 1968 |
The role of pteridine cofactors in mixed function oxidases.
Topics: Adrenal Glands; Animals; Cattle; Liver; Mixed Function Oxygenases; NADP; Phenylalanine; Pteridines; Rats; Tyrosine | 1968 |
The formation of 3,4-dihydroxy-L-phenylalanine from L-meta-tyrosine by rat liver and beef adrenal medulla.
Topics: Adrenal Glands; Amino Acids; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Cattle; Chemical Precipitation; Chromatography, Ion Exchange; Cresols; Depression, Chemical; Dihydroxyphenylalanine; Ethanol; Female; Fluorescence; Hydroxylamines; Isomerism; Liver; Mixed Function Oxygenases; NADP; Phenylalanine; Pteridines; Quaternary Ammonium Compounds; Rats; Stimulation, Chemical; Sulfates; Tyrosine | 1971 |
Evidence for a tyrosine residue at the triphosphopyridine nucleotide-binding site of 6-phosphogluconate dehydrogenase.
Topics: Binding Sites; Candida; Chemical Phenomena; Chemistry; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Methane; NADP; Nitro Compounds; Oxidation-Reduction; Phosphogluconate Dehydrogenase; Spectrophotometry; Sulfhydryl Compounds; Sulfites; Tyrosine | 1971 |
[Hydroxylation of phenylalanine by Hydrogenomonas eutropha H 16].
Topics: Cell-Free System; Chromatography, Gel; Enzyme Induction; Mixed Function Oxygenases; NAD; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pseudomonas; Tryptophan; Tyrosine | 1972 |
Evidences for the involvement of a histidine residue in the binding of the substrate to the 6-phosphogluconate dehydrogenase.
Topics: Alkanes; Binding Sites; Carbon Isotopes; Carbonates; Chemical Phenomena; Chemistry; Dialysis; Gluconates; Glucose; Glucosephosphates; Histidine; Hydrogen-Ion Concentration; Kinetics; NADP; Nitro Compounds; Phosphogluconate Dehydrogenase; Phosphoric Acids; Protein Binding; Spectrophotometry; Tritium; Tyrosine | 1972 |
The role of NADP-dependent dehydrogenases in hydroxylation of tyrosine in hamster melanoma.
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; Electrophoresis, Polyacrylamide Gel; Hydroxylation; Melanoma; Monophenol Monooxygenase; NADP; NADPH Dehydrogenase; Neoplasm Transplantation; Neoplasms, Experimental; Oxidoreductases; Tyrosine | 1983 |
Modification of tyrosine residues in dihydrofolate reductase from Lactobacillus casei.
Topics: 4-Chloro-7-nitrobenzofurazan; Enzyme Activation; Folic Acid; Kinetics; Lacticaseibacillus casei; NADP; Protein Conformation; Tetrahydrofolate Dehydrogenase; Tetranitromethane; Tyrosine | 1982 |
Characterization of the dihydropterin reductase activity of pig liver methylenetetrahydrofolate reductase.
Topics: Animals; Biopterins; Cell-Free System; Dihydropteridine Reductase; In Vitro Techniques; Liver; Methylenetetrahydrofolate Dehydrogenase (NADP); NAD; NADH, NADPH Oxidoreductases; NADP; Oxidoreductases; Quinones; Swine; Tetrahydrofolates; Tyrosine; Vitamin K | 1980 |
Arogenate (pretyrosine) pathway of tyrosine and phenylalanine biosynthesis in Pseudomonas aureofaciens ATCC 15926.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; NAD; NADP; Oxidoreductases; Phenylalanine; Prephenate Dehydrogenase; Pseudomonas; Tyrosine | 1982 |
In vitro biosynthesis of the cyanogenic glucoside taxiphyllin in Triglochin maritima.
Topics: Glucosides; Glycosides; In Vitro Techniques; Microsomes; NADP; Nitriles; Plants; Tyrosine | 1980 |
Roles of Arg231 and Tyr284 of Thermus thermophilus isocitrate dehydrogenase in the coenzyme specificity.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; DNA, Bacterial; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Thermus thermophilus; Tyrosine | 1994 |
NADPH-initiated cytochrome P450-mediated free metal ion-independent oxidative damage of microsomal proteins. Exclusive prevention by ascorbic acid.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guinea Pigs; Hydrolysis; Iron; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Proteins; Tryptophan; Tyrosine | 1994 |
Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
Topics: Aldehyde Reductase; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; DNA Primers; Female; Histidine; Humans; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Placenta; Pregnancy; Protein Conformation; Recombinant Proteins; Tyrosine | 1993 |
Role of tyrosine residues in Hg(II) detoxification by mercuric reductase from Bacillus sp. strain RC607.
Topics: Amino Acid Sequence; Bacillus; Base Sequence; Kinetics; Mercury; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxidoreductases; Thermodynamics; Tyrosine; X-Ray Diffraction | 1993 |
NADPH-sulfite reductase from Escherichia coli. A flavin reductase participating in the generation of the free radical of ribonucleotide reductase.
Topics: Amino Acid Sequence; Blotting, Western; Catalysis; Electron Transport; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; FMN Reductase; Free Radicals; Hydroxyurea; Molecular Sequence Data; Molecular Weight; Mutation; NADH, NADPH Oxidoreductases; NADP; Oxidoreductases Acting on Sulfur Group Donors; Ribonucleotide Reductases; Sulfite Reductase (NADPH); Tyrosine | 1993 |
Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba L.
Topics: Carbon Monoxide; Cyclopentanes; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glucosinolates; Kinetics; Light; Microsomes; Mustard Plant; NADP; Oximes; Oxygen; Oxylipins; Plants, Medicinal; Tyrosine | 1995 |
The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls.
Topics: Bacterial Proteins; Binding Sites; Carbohydrate Dehydrogenases; Cell Wall; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Structure; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation; Tyrosine; Uridine Diphosphate N-Acetylglucosamine | 1996 |
The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Catalysis; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Estradiol; Estradiol Dehydrogenases; Estrone; Female; Humans; Macromolecular Substances; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NADP; Oxidation-Reduction; Oxygen; Placenta; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Substrate Specificity; Temperature; Tyrosine | 1996 |
Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Blotting, Western; Cattle; Ferric Compounds; Kinetics; Lipid Peroxides; NAD; NADP; NADP Transhydrogenases; Nitrates; Oxidation-Reduction; Peptide Mapping; Stress, Physiological; Submitochondrial Particles; Tyrosine; Ubiquinone | 1996 |
Peroxynitrite modification of glutathione reductase: modeling studies and kinetic evidence suggest the modification of tyrosines at the glutathione disulfide binding site.
Topics: Animals; Binding Sites; Blotting, Western; Cattle; Glutathione; Glutathione Reductase; Hydrogen Bonding; Intestinal Mucosa; Kinetics; Models, Molecular; NADP; Nitrates; Protein Binding; Protein Conformation; Solvents; Spectrometry, Fluorescence; Tyrosine | 1996 |
A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance.
Topics: Binding Sites; Chromosomes, Bacterial; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Conformation; NADP; Phenylalanine; Point Mutation; Protein Conformation; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase; Trimethoprim; Trimethoprim Resistance; Tyrosine | 1997 |
Isocyanate binding to yeast glutathione reductase measured by fluorescence spectroscopy.
Topics: Binding Sites; Glutathione; Glutathione Disulfide; Glutathione Reductase; Isocyanates; NADP; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Tyrosine | 1997 |
Mutations at tyrosine-235 in the mobile loop region of domain I protein of transhydrogenase from Rhodospirillum rubrum strongly inhibit hydride transfer.
Topics: Hydrogen; Mutation; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Rhodospirillum rubrum; Tyrosine | 1997 |
Importance of glucose-6-phosphate dehydrogenase activity for cell growth.
Topics: 3T3 Cells; Animals; Cell Division; COS Cells; Dehydroepiandrosterone; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Mice; NADP; Oxidation-Reduction; Phosphorylation; Ribosemonophosphates; Thymidine; Tyrosine | 1998 |
Retention of NADPH-linked quinone reductase activity in an aldo-keto reductase following mutation of the catalytic tyrosine.
Topics: 3-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Catalysis; Energy Transfer; Enzyme Activation; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Mutagens; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Phenanthrenes; Rats; Substrate Specificity; Tyrosine | 1998 |
Role of active site tyrosine residues in catalysis by human glutathione reductase.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Electron Transport; Enzyme Activation; Fluorescence Polarization; Glutathione; Glutathione Reductase; Humans; Leucine; NADP; Oxidation-Reduction; Serine; Spectrometry, Fluorescence; Tyrosine | 1998 |
Peroxynitrite-mediated nitration of tyrosine and inactivation of the catalytic activity of cytochrome P450 2B1.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP2B1; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gas Chromatography-Mass Spectrometry; Microsomes, Liver; NADP; Nitrates; Nitric Oxide; Rats; Rats, Long-Evans; tert-Butylhydroperoxide; Tyrosine | 1998 |
Oxidation of guaiacol by myeloperoxidase: a two-electron-oxidized guaiacol transient species as a mediator of NADPH oxidation.
Topics: Biphenyl Compounds; Electrons; Guaiacol; Humans; Hydrogen Peroxide; Kinetics; NADP; Oxidation-Reduction; Peroxidase; Pyridines; Quinones; Superoxide Dismutase; Tetranitromethane; Tyrosine | 1998 |
Kinetic mechanism of cytochrome P450 reductase from the house fly (Musca domestica).
Topics: Animals; Cysteine; Cytochrome c Group; Electrons; Houseflies; Kinetics; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Recombinant Fusion Proteins; Tyrosine | 1999 |
A productive NADP+ binding mode of ferredoxin-NADP + reductase revealed by protein engineering and crystallographic studies.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Crystallization; Crystallography, X-Ray; Ferredoxin-NADP Reductase; Ligands; Models, Molecular; Molecular Sequence Data; NADP; Pisum sativum; Protein Binding; Protein Conformation; Protein Engineering; Spectrum Analysis; Thermodynamics; Tyrosine | 1999 |
Denitration of peroxynitrite-treated proteins by 'protein nitratases' from rat brain and heart.
Topics: Animals; beta-Fructofuranosidase; Blotting, Western; Brain; Brain Chemistry; Calcium; Dialysis; Enzymes; Flavin-Adenine Dinucleotide; Glutathione; Glutathione Transferase; Glycoside Hydrolases; Myocardium; NAD; NADP; Nitrates; Proteins; Rats; Serum Albumin, Bovine; Tissue Extracts; Tyrosine | 1999 |
Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism.
Topics: Amino Acid Sequence; Amitrole; Binding Sites; Catalase; Catalysis; Crystallization; Crystallography, X-Ray; Cyanides; Electrons; Enzyme Inhibitors; Heme; Humans; Hydrogen Bonding; Hydrogen Peroxide; Models, Chemical; Models, Molecular; Molecular Sequence Data; NADP; Protein Conformation; Substrate Specificity; Tyrosine; Water | 2000 |
Competition between C-terminal tyrosine and nicotinamide modulates pyridine nucleotide affinity and specificity in plant ferredoxin-NADP(+) reductase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Binding, Competitive; Chloroplasts; Ferredoxin-NADP Reductase; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Niacinamide; Pisum sativum; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2000 |
Steady-state and transient kinetics of Escherichia coli nitric-oxide dioxygenase (flavohemoglobin). The B10 tyrosine hydroxyl is essential for dioxygen binding and catalysis.
Topics: Amino Acids; Dose-Response Relationship, Drug; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Ligands; Models, Biological; Mutagenesis; NADP; Nitric Oxide; Oxidation-Reduction; Oxygen; Oxygenases; Time Factors; Tyrosine | 2000 |
Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Freezing; Glutamic Acid; Isocitrate Dehydrogenase; Macromolecular Substances; Magnesium; Malates; NADP; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2001 |
The crystal structure of an aldehyde reductase Y50F mutant-NADP complex and its implications for substrate binding.
Topics: Aldehyde Reductase; Animals; Base Sequence; Catalytic Domain; Crystallography, X-Ray; DNA Primers; Hydrogen Bonding; In Vitro Techniques; NADP; Point Mutation; Spectrometry, Fluorescence; Substrate Specificity; Swine; Tyrosine | 2001 |
Mutational study of the role of tyrosine-49 in the Saccharomyces cerevisiae xylose reductase.
Topics: Aldehyde Reductase; Cloning, Molecular; Escherichia coli; Kinetics; Mutagenesis, Site-Directed; NADP; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment; Tyrosine; Xylose | 2001 |
Involvement of the flavin si-face tyrosine on the structure and function of ferredoxin-NADP+ reductases.
Topics: Animals; Binding Sites; DNA, Complementary; Escherichia coli; Ferredoxin-NADP Reductase; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NADP; Oxygen; Phenol; Pisum sativum; Protein Binding; Protein Structure, Secondary; Spectrophotometry; Substrate Specificity; Thermodynamics; Time Factors; Tyrosine | 2001 |
Tyr275 and Lys279 stabilize NADPH within the catalytic site of NADPH:protochlorophyllide oxidoreductase and are involved in the formation of the enzyme photoactive state.
Topics: Amino Acid Substitution; Binding Sites; Catalytic Domain; Enzyme Activation; Enzyme Stability; Freezing; Kinetics; Lysine; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Photochemistry; Pisum sativum; Protein Denaturation; Protochlorophyllide; Rhodobacter capsulatus; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Tyrosine | 2001 |
Protein denitration/modification by Escherichia coli nitrate reductase and mammalian cytochrome P-450 reductase.
Topics: Animals; Escherichia coli; Histones; Models, Chemical; NADP; NADPH-Ferrihemoprotein Reductase; Nitrate Reductase; Nitrate Reductases; Nitrates; Peroxynitrous Acid; Tyrosine | 2002 |
Exploring the active site of plant glutaredoxin by site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acids, Aromatic; Binding Sites; Dehydroascorbic Acid; Disulfides; Enzyme Activation; Ethanol; Glutaredoxins; Magnoliopsida; Malate Dehydrogenase; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Oxidoreductases; Plant Proteins; Proteins; Trees; Tyrosine | 2002 |
Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis.
Topics: Animals; Biopterins; Brain; Calcium; Calmodulin; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Flavin-Adenine Dinucleotide; Male; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Protein Isoforms; Rats; Rats, Inbred Lew; RNA, Messenger; Subcellular Fractions; Tyrosine | 2002 |
Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Enzyme Activation; Female; Humans; Lipid Peroxidation; Male; Middle Aged; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Superoxides; Thiobarbituric Acid Reactive Substances; Tyrosine | 2002 |
Anabaena sp. PCC 7119 flavodoxin as electron carrier from photosystem I to ferredoxin-NADP+ reductase. Role of Trp(57) and Tyr(94).
Topics: Anabaena; Desulfovibrio vulgaris; Dose-Response Relationship, Drug; Electrons; Ferredoxin-NADP Reductase; Flavodoxin; Kinetics; Microscopy, Fluorescence; Models, Chemical; Mutation; NADP; Photosynthetic Reaction Center Complex Proteins; Protein Binding; Riboflavin; Spectrophotometry; Thermodynamics; Time Factors; Tryptophan; Tyrosine; Ultraviolet Rays | 2002 |
Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.
Topics: Alanine; Amino Acid Substitution; Ascorbic Acid; Binding Sites; Corynebacterium; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gluconates; Glycine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Phenylalanine; Recombinant Fusion Proteins; Sugar Alcohol Dehydrogenases; Thermodynamics; Tyrosine | 2002 |
Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; DNA, Complementary; Humans; In Vitro Techniques; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; NAD; NADP; Protein Structure, Secondary; Rats; Sequence Homology, Amino Acid; Swine; Tyrosine | 2002 |
Site-directed mutagenesis of Tyr-189 and Lys-193 in NADPH: protochlorophyllide oxidoreductase from Synechocystis.
Topics: Amino Acid Substitution; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; Cyanobacteria; DNA Primers; Escherichia coli; Kinetics; Lysine; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Tyrosine | 2002 |
Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor.
Topics: Dihydrolipoamide Dehydrogenase; Guanine; NADP; Nitrogen Oxides; Oxidation-Reduction; Reactive Nitrogen Species; Thioctic Acid; Tyrosine; Ubiquinone; Xanthines | 2002 |
Purification and kinetic analysis of the two recombinant arogenate dehydrogenase isoforms of Arabidopsis thaliana.
Topics: Amino Acid Sequence; Amino Acids, Dicarboxylic; Arabidopsis; Base Sequence; Cyclohexenes; DNA, Plant; Enzyme Inhibitors; Escherichia coli; Isoenzymes; Kinetics; Molecular Sequence Data; NADP; Prephenate Dehydrogenase; Recombinant Proteins; Sequence Homology, Amino Acid; Tyrosine | 2002 |
Differential effects of mutations in human endothelial nitric oxide synthase at residues Tyr-357 and Arg-365 on L-arginine hydroxylation and GN-hydroxy-L-arginine oxidation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; Catalysis; Chromatography, Gel; DNA Primers; Humans; Hydroxylation; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Recombinant Proteins; Tyrosine | 2003 |
Pre-steady-state and steady-state kinetic analysis of E. coli class I ribonucleotide reductase.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Binding Sites; Deoxycytosine Nucleotides; Escherichia coli; Free Radicals; Kinetics; NADP; Oxidation-Reduction; Protein Conformation; Protein Subunits; Ribonucleotide Reductases; Spectrophotometry, Ultraviolet; Thioredoxin-Disulfide Reductase; Thioredoxins; Tyrosine | 2003 |
The requirement of monoiodotyrosine deiodinase for triphosphopyridine nucleotide.
Topics: Coenzymes; Enzymes; Iodide Peroxidase; Monoiodotyrosine; NADP; Tyrosine | 1957 |
PREPARATION OF PREPHENIC ACID AND ITS CONVERSION TO PHENYLALANINE AND TYROSINE BY PLANT ENZYMES.
Topics: Autoanalysis; Barium; Cyclohexanecarboxylic Acids; Cyclohexenes; Escherichia coli; Fermentation; Glutamates; Infrared Rays; Ion Exchange Resins; NADP; Peptones; Phenylalanine; Phenylpyruvic Acids; Plants, Edible; Proteins; Research; Transaminases; Tyrosine; Yeasts | 1964 |
Reactive oxygen species promote tyrosine phosphorylation and capacitation in equine spermatozoa.
Topics: Animals; Blotting, Western; Catalase; Electrophoresis, Polyacrylamide Gel; Horses; Hydrogen Peroxide; Male; NADP; Phosphorylation; Reactive Oxygen Species; Sperm Capacitation; Spermatozoa; Superoxide Dismutase; Superoxides; Tyrosine; Xanthine; Xanthine Oxidase | 2003 |
Cyclic AMP-dependent tyrosine phosphorylation in tammar wallaby (Macropus eugenii) spermatozoa.
Topics: Animals; Blotting, Western; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Immunohistochemistry; Luminescent Measurements; Macropodidae; Male; NADP; Phosphorylation; Signal Transduction; Spermatozoa; Tyrosine | 2004 |
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine | 2004 |
Oxidative DNA damage induced by nitrotyrosine, a biomarker of inflammation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Biomarkers; Copper; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Humans; Inflammation; NADP; NADPH-Ferrihemoprotein Reductase; Oxidative Stress; Phenanthrolines; Tyrosine | 2004 |
The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48.
Topics: Aldehyde Reductase; Binding Sites; Carboxylic Acids; Crystallography, X-Ray; Enzyme Inhibitors; Fluorobenzenes; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; NADP; Protein Structure, Tertiary; Protons; Thiazoles; Tyrosine | 2004 |
"Catch 222," the effects of symmetry on ligand binding and catalysis in R67 dihydrofolate reductase as determined by mutations at Tyr-69.
Topics: Binding Sites; Calorimetry; Catalysis; Dimerization; Escherichia coli; Hydrogen-Ion Concentration; Ions; Kinetics; Leucine; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NADP; Protein Binding; Protein Structure, Tertiary; Tetrahydrofolate Dehydrogenase; Thermodynamics; Tyrosine | 2004 |
Towards a new interaction enzyme:coenzyme.
Topics: Anabaena; Apoenzymes; Ferredoxin-NADP Reductase; Flavin-Adenine Dinucleotide; Kinetics; Mutation; NADP; Oxidation-Reduction; Spectrum Analysis; Tyrosine | 2005 |
Detection and comparison of nitric oxide in clinically healthy horses and those with naturally acquired strangulating large colon volvulus.
Topics: Animals; Case-Control Studies; Colon; Colonic Diseases; Female; Horse Diseases; Horses; Immunohistochemistry; Intestinal Volvulus; Male; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tyrosine | 2005 |
NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Catalysis; Chromatography, Gel; Coumarins; Mutation; NADP; Novobiocin; Oxidation-Reduction; Oxidoreductases; Pantetheine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomyces; Tyrosine; Ultracentrifugation | 2005 |
C-terminal tyrosine of ferredoxin-NADP+ reductase in hydride transfer processes with NAD(P)+/H.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anabaena; Crystallization; Ferredoxin-NADP Reductase; Hydrogen; Molecular Structure; NAD; NADP; Pisum sativum; Tyrosine | 2005 |
Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; NADP; Nucleotides; Prephenate Dehydrogenase; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Synechocystis; Tyrosine | 2006 |
Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Chlorogenic Acid; Endothelium, Vascular; Hydrogen Peroxide; Immunohistochemistry; In Vitro Techniques; Male; NADP; NADPH Oxidases; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Quinic Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Tyrosine; Vasodilation | 2006 |
Cell signaling. H2O2, a necessary evil for cell signaling.
Topics: Cell Membrane; Cysteine; Cytosol; Humans; Hydrogen Peroxide; NADP; Organelles; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Receptors, Cell Surface; Signal Transduction; Tyrosine | 2006 |
The roles of Tyr(91) and Lys(162) in general acid-base catalysis in the pigeon NADP+-dependent malic enzyme.
Topics: Acids; Alkalies; Catalysis; Circular Dichroism; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Molecular Structure; Mutation; NADP; Oxidation-Reduction; Recombinant Proteins; Substrate Specificity; Tyrosine | 2008 |
Nitrotyrosine promotes human aortic smooth muscle cell migration through oxidative stress and ERK1/2 activation.
Topics: Aorta; Biological Transport; Cell Movement; Cells, Cultured; Enzyme Activation; Humans; Integrins; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADP; Oxidative Stress; Reactive Oxygen Species; Receptor, Platelet-Derived Growth Factor beta; Tyrosine | 2008 |
Effect of nitric oxide on auditory cortical neurons of aged rats.
Topics: Age Factors; Aging; Animals; Auditory Cortex; In Vitro Techniques; Male; Membrane Potentials; NADP; Neurons; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Rats; Rats, Sprague-Dawley; Tyrosine | 2008 |
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.
Topics: Amino Acid Sequence; Apoptosis; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Phylogeny; Protein Structure, Quaternary; Proto-Oncogene Proteins; Reactive Oxygen Species; Recombinant Proteins; Sequence Homology, Amino Acid; Tumor Suppressor Protein p53; Tyrosine | 2009 |
Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase.
Topics: Catalytic Domain; Cold Temperature; Fluorescence; Kinetics; Lasers; Light; Lysine; Mutagenesis; NADP; Oxidoreductases Acting on CH-CH Group Donors; Photochemical Processes; Protein Structure, Tertiary; Protons; Synechococcus; Tyrosine | 2009 |
Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.
Topics: Animals; Apoenzymes; Crystallography, X-Ray; Holoenzymes; Hydroxysteroid Dehydrogenases; Mice; Models, Molecular; Mutation; NADP; Protein Binding; Protein Structure, Tertiary; Substrate Specificity; Tyrosine | 2010 |
A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate.
Topics: ADP-ribosyl Cyclase; Amino Acid Sequence; Animals; Blastomeres; Blotting, Western; Cell Line; Cloning, Molecular; Cyclic ADP-Ribose; Humans; Kinetics; Microinjections; Microscopy, Confocal; Molecular Sequence Data; Mutation; NADP; Sequence Homology, Amino Acid; Strongylocentrotus purpuratus; Transfection; Tyrosine; Xenopus laevis | 2010 |
Endogenous reactive oxygen species content and modulation of tyrosine phosphorylation during sperm capacitation.
Topics: Adult; Blotting, Western; Humans; Immunohistochemistry; Luminescence; Male; NADP; Phosphorylation; Reactive Oxygen Species; Sperm Capacitation; Tyrosine | 2011 |
Luteolin protects osteoblastic MC3T3-E1 cells from antimycin A-induced cytotoxicity through the improved mitochondrial function and activation of PI3K/Akt/CREB.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Calcium; Cardiolipins; Cell Line; Cell Survival; Cyclic AMP Response Element-Binding Protein; Cytochromes c; Luteolin; Membrane Potential, Mitochondrial; Mice; Mitochondria; NADP; Osteoblasts; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Thioredoxin-Disulfide Reductase; Tyrosine | 2011 |
A single tyrosine hydroxyl group almost entirely controls the NADPH specificity of Plasmodium falciparum ferredoxin-NADP+ reductase.
Topics: Amino Acid Substitution; Binding Sites; Coenzymes; Ferredoxin-NADP Reductase; Kinetics; NAD; NADP; Plasmodium falciparum; Substrate Specificity; Tyrosine | 2012 |
Theoretical study of the mechanism of the hydride transfer between ferredoxin-NADP+ reductase and NADP+: the role of Tyr303.
Topics: Ferredoxin-NADP Reductase; Models, Molecular; Molecular Dynamics Simulation; NADP; Tyrosine | 2012 |
A single amino acid determines the catalytic efficiency of two alkenal double bond reductases produced by the liverwort Plagiochasma appendiculatum.
Topics: Aldehydes; Amino Acid Sequence; Biocatalysis; Cysteine; Escherichia coli; Hepatophyta; Kinetics; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Phylogeny; Plant Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2013 |
Induced fit docking, pharmacophore modeling, and molecular dynamic simulations on thiazolidinedione derivatives to explore key interactions with Tyr48 in polyol pathway.
Topics: Aldehyde Reductase; Amino Acid Sequence; Binding Sites; Computer-Aided Design; Drug Design; Enzyme Inhibitors; Hydrogen Bonding; Hypoglycemic Agents; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Molecular Structure; NADP; Polymers; Protein Binding; Protein Conformation; Structure-Activity Relationship; Thiazolidinediones; Tyrosine | 2014 |
Delineating the reaction mechanism of reductase domains of Nonribosomal Peptide Synthetases from mycobacteria.
Topics: Bacterial Proteins; Binding Sites; Binding, Competitive; Calorimetry; Catalytic Domain; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; NADP; Niacinamide; Peptide Synthases; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Scattering, Small Angle; Thermodynamics; Tyrosine; X-Ray Diffraction | 2014 |
Replacement of Tyr50 stacked on the si-face of the isoalloxazine ring of the flavin adenine dinucleotide prosthetic group modulates Bacillus subtilis ferredoxin-NADP(+) oxidoreductase activity toward NADPH.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Ferredoxin-NADP Reductase; Ferredoxins; Flavin-Adenine Dinucleotide; Flavins; Models, Molecular; Molecular Sequence Data; Mutation, Missense; NADP; Sequence Alignment; Tyrosine | 2015 |
A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Amino Acid Sequence; Amino Acid Substitution; Animals; Biocatalysis; Catalytic Domain; Chickens; Databases, Protein; Disease Models, Animal; Fatty Liver; Gene Expression Regulation, Enzymologic; Hypothyroidism; Liver; Molecular Sequence Data; Mutant Proteins; NADP; Phenanthrenes; Protein Conformation; Protein Stability; Protein Subunits; Recombinant Proteins; Tyrosine | 2015 |
Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Models, Molecular; Mutagenesis; Mutation; NADP; Protein Binding; Protein Conformation; Tyrosine; Vibrio cholerae | 2016 |
Biochemical characterization of TyrA enzymes from Ignicoccus hospitalis and Haemophilus influenzae: A comparative study of the bifunctional and monofunctional dehydrogenase forms.
Topics: Amino Acid Sequence; Bacterial Proteins; Chorismate Mutase; Desulfurococcaceae; Escherichia coli; Haemophilus influenzae; Histidine; Multienzyme Complexes; NAD; NADP; Prephenate Dehydrogenase; Tyrosine | 2017 |
Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; HEK293 Cells; Humans; Kinetics; Mice; Mice, Nude; Models, Molecular; NADP; Neoplasms; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Phosphorylation; Radiation, Ionizing; Reactive Oxygen Species; Ribosemonophosphates; Tyrosine; Up-Regulation | 2019 |
Characterization of Light-Induced, Short-Lived Interacting Radicals in the Active Site of Flavoprotein Ferredoxin-NADP
Topics: Bacillus subtilis; Catalytic Domain; Electron Transport; Ferredoxin-NADP Reductase; Free Radicals; Light; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; NADP; Protein Binding; Quantum Theory; Tryptophan; Tyrosine | 2021 |