tyrosine has been researched along with nad in 133 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 62 (46.62) | 18.7374 |
1990's | 24 (18.05) | 18.2507 |
2000's | 28 (21.05) | 29.6817 |
2010's | 19 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Friedrich, B; Friedrich, CG; Schlegel, HG | 1 |
Kaufman, S | 1 |
Blakley, ER | 1 |
Beugnier, N; Zanen, J | 1 |
Allen, G; Harris, JI | 1 |
Dénes, G; Nagy, J | 1 |
Ban, TA | 1 |
Laws, WR; Shore, JD | 1 |
Estabrook, RW; Graf, H; Kawano, S; Kuthan, H; Tsuji, H; Ullrich, V; Werringloer, J | 1 |
Fan, CC; Plaut, GW; Tomcho, LA | 1 |
Blumenthal, KM; Smith, EL | 1 |
Yamamoto, HA | 1 |
Brearley, GM; Campbell, RS; Hall, SK; Hammond, PM; Milligan, TP; Morris, HC; Price, CP; Varsani, H | 1 |
Domenighini, M; Montecucco, C; Neri, P; Papini, E; Rappuoli, R; Santucci, A; Schiavo, G | 1 |
Davis, MD; Kaufman, S | 1 |
Burdett, E; Klip, A; Mills, GB | 1 |
Jensen, RA; Xia, TH | 1 |
van der Walt, BJ; Van Zyl, JM | 1 |
Ibrahim, M; Lohmann, C; Lohmann, W | 1 |
Nishino, T | 1 |
Christopherson, RI | 1 |
Aki, K; Maeda-Yorita, K | 1 |
De Bersaques, J | 1 |
Colman, RF; Frieden, C | 1 |
Birkmayer, W; Mentasti, M | 1 |
Keleti, T | 1 |
Moses, D; Weiner, M | 1 |
Bray, D; Kapoor, M | 1 |
Hayaishi, O; Nozaki, M | 1 |
Cassen, T; Kearns, DR | 1 |
Watts, GK | 1 |
Jakubiec-Puka, A; Mochnacka, I | 1 |
Birkmayer, W | 1 |
Champney, WS; Jensen, RA | 1 |
Odajima, T | 1 |
Ellison, JS; Siegel, L | 1 |
Steinberg, IZ | 1 |
Chan-Henry, E; Jakubovic, A; Woolf, LI | 1 |
Imahori, K; Suzuki, K | 1 |
Axén, R; Vretblad, P | 1 |
Emes, AV; Hassall, H | 1 |
Kaback, HR; Lombardi, FJ; Reeves, JP; Short, SA | 1 |
Jeckel, D | 1 |
Matsuzaki, S; Suzuki, M | 1 |
Abbassi, V; Bastomsky, CH; McKenzie, JM | 1 |
Benoiton, NL; D'Iorio, A; Tong, JH | 1 |
Friedrich, B; Schlegel, HG | 1 |
Davidson, BE; Howlett, GJ; Hudson, GS | 1 |
Colman, RF; Schmidt, JA | 1 |
Hatefi, Y; Vik, SB | 1 |
Bednar, RA; Colman, RF; Saradambal, KV | 1 |
Abu El Failat, RR; Davies, JV; Moore, JS | 1 |
Lechene, C; Mroz, EA | 1 |
Kaufman, S; Matthews, RG | 1 |
Holbrook, JJ; Jeckel, D; Parker, DM | 1 |
Keller, B; Keller, E; Lingens, F; Salcher, O | 1 |
Chan, RM; Crabb, DW; Harris, RA; Hawes, JW; Rougraff, PM | 1 |
Miyazaki, K; Oshima, T; Yaoi, T | 1 |
Ensor, CM; Tai, HH | 1 |
Ahmad, S; Bragg, PD; Glavas, NA; Holmberg, E; Hultman, T; Olausson, T; Rydström, J | 1 |
Fujimoto, S; Kawakami, N; Ohara, A | 1 |
Bizouarn, T; Cotton, NP; Diggle, C; Grimley, RI; Jackson, JB; Quirk, PG; Thomas, CM | 1 |
Dallner, G; Ernster, L; Forsmark-Andrée, P; Persson, B; Radi, R | 1 |
Bizouarn, T; Diggle, C; Grimley, R; Jackson, JB; Thomas, CM | 1 |
Huang, T; Kuwana, T; Scheller, FW; Warsinke, A | 1 |
Conrads, T; Hemann, C; Hille, R | 1 |
Adachi, Y; Cookingham, G; Kindzelskii, AL; Moore, EC; Petty, HR; Shaya, S; Todd, RF | 1 |
Holden, HM; Thoden, JB | 1 |
Adler, S; Blanco, G; Evans, BW; Isenberg, KE; Mason, JI; Mercer, RW; Nash, WE; Strickler, RC; Thomas, JL | 1 |
Caputi, AP; Costantino, G; Cuzzocrea, S | 1 |
Caputi, AP; Ciriaco, E; Costantino, G; Cuzzocrea, S; de Sarro, A; de Sarro, G; Laurà, R; Mazzon, E | 1 |
Moynihan, DP; Parikh, S; Tonge, PJ; Xiao, G | 1 |
Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E | 1 |
Kanadia, RN; Kuo, WN; Shanbhag, VP; Toro, R | 1 |
Blackshaw, S; Brat, DJ; Clements, EE; Conover, JR; Favit, A; Krug, DK; Pieper, AA; Pinto-Garcia, P; Snyder, SH; Verma, A; White, AJ | 1 |
Aliverti, A; Arakaki, AK; Carrillo, N; Ceccarelli, EA; Karplus, PA; Piubelli, L; Zanetti, G | 1 |
Fridovich-Keil, JL; Holden, HM; Thoden, JB; Wohlers, TM | 1 |
Dolan, KM; Lindenmayer, G; Olson, JC | 1 |
Alvarez, S; Arnaiz, SL; Boveris, A; Carreras, MC; Poderoso, JJ; Schöpfer, F; Valdez, LB | 1 |
Moyer, RW; Shuman, S; Sriskanda, V | 1 |
Al-Affar, EB; Liaudet, L; Szabó, C; Yang, Z | 1 |
Cleland, WW; Frey, PA; Gerratana, B | 1 |
Boveris, A; Cadenas, E; Clementi, E; Melani, M; Moncada, S; Poderoso, JJ; Riobó, NA | 1 |
Iyanagi, T; Kimura, S; Nishida, H | 1 |
Cocklin, S; Dodds, A; Hawkins, AR; Lamb, HK; Leslie, K; Nichols, CE; Ren, J; Stammers, DK | 1 |
Shuman, S; Sriskanda, V | 1 |
Anderson, S; Banta, S; Jarnagin, A; Swanson, BA; Wu, S | 1 |
Colman, RF; Lee, P | 1 |
Kim, YH; Koh, JY | 1 |
Atrian, S; Benach, J; Gonzàlez-Duarte, R; Karshikoff, A; Koumanov, A; Ladenstein, R | 1 |
MANDEL, P | 1 |
GUROFF, G; ITO, T | 2 |
KIMURA, S; MIKUNI, M; TAKESHIMA, M | 1 |
MAXWELL, ES; TOMKINS, GM | 1 |
KAPLAN, NO; MCKAY, RH | 1 |
CHAN, SK; COHEN, PP | 1 |
YOUNG, DA | 1 |
SUZUKI, Y | 1 |
SHIFRIN, S | 1 |
BERENHOLC, M; CILENTO, G | 1 |
YIP, CC | 1 |
Buryanov, Y; Felipo, V; Giordano, G; Kaminsky, Y; Kosenko, E; Montoliu, C; Venediktova, N | 1 |
Cook, PF; Harris, BG; Karsten, WE; Liu, D; Rao, GS | 1 |
Deutscher, J; Mijakovic, I; Petranovic, D | 1 |
Gómez-Moreno, C; Hermoso, JA; Martínez-Júlvez, M; Maya, C; Medina, M; Pérez-Dorado, I; Sanz-Aparicio, J; Tejero, J | 1 |
Basran, J; Combe, JP; Hothi, P; Leys, D; Munro, AW; Rigby, SE; Scrutton, NS | 1 |
Barić, I; Beluzić, R; Cuk, M; Fumić, K; Jurak, I; Mudd, SH; Pavkov, T; Vugrek, O | 1 |
Kawanishi, S; Kurimoto, S; Murata, M | 1 |
Dennis, M; Hassler, BL; Laivenieks, M; Worden, RM; Zeikus, JG | 1 |
Abraham, P; Rabi, S | 2 |
Klimacek, M; Kratzer, R; Nidetzky, B; Pival, SL | 1 |
Bonvin, J; Christendat, D; Hou, W; Kimber, MS; Shahinas, D; Sun, W; Turnbull, J | 1 |
Chang, YH; Chiu, CC; Chuang, LY; Hwang, CC; Wang, CZ | 1 |
Miyagi, M; Palamalai, V | 1 |
Adams, S; Braidy, N; Grant, R; Guillemin, GJ | 1 |
Abuhammad, A; Laurieri, N; Lowe, E; Ryan, A; Sim, E; Wang, CJ; Westwood, I | 1 |
Boggon, TJ; Chen, GZ; Chen, J; Chung, TW; Fan, J; Ge, Q; Gu, TL; Hitosugi, T; Kang, S; Khuri, FR; Lonial, S; Polakiewicz, RD; Xie, J | 1 |
Day, BJ; Huang, TT; Liang, LP; Patel, M; Rowley, S; Waldbaum, S | 1 |
Chuang, MC; Ho, JA; Prasad, KS | 1 |
Aliverti, A; Baroni, S; Pandini, V; Vanoni, MA | 1 |
Withers, SG; Yip, VL | 1 |
Alsaeed, AH; AlSalhi, MS; Devanesan, S; Ganesh, KM; Masilamani, V; Palled, S; Perinbam, K; Prasad, S; Ravikumar, M | 1 |
Areti, A; Gogoi, R; Komirishetty, P; Kumar, A; Ruby, PK; Sharma, SS; Sistla, R; Yerra, VG | 1 |
Fu, J; Li, S; Li, X; Li, Y; Wang, L; Yang, Q; Zhang, Y; Zhen, L | 1 |
Hoque, MM; Kanazawa, H; Kawai, G; Kondo, J; Suzuki, K; Takénaka, A; Tsunoda, M; Yamamoto, T | 1 |
Hayashi, H; Kamitori, S; Kobayashi, J; Mikami, B; Mizutani, K; Takahashi, N; Yagi, T; Yoshida, H | 1 |
First, EA; Richardson, CJ | 1 |
Kim, HY; Quashie, PK; Shlaifer, I; Turnbull, JL | 1 |
Dudzik, A; Jemioła-Rzemińska, M; Skoczowski, A; Stawoska, I; Strzałka, K; Szaleniec, M; Wasylewski, M | 1 |
Gorelik, A; Illes, K; Nagar, B; Randriamihaja, A | 1 |
Inaba, S; Oda, M; Shiota, A; Yoshida, T | 1 |
6 review(s) available for tyrosine and nad
Article | Year |
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Alcoholism and schizophrenia: diagnostic and therapeutic considerations.
Topics: Alcoholism; Brain; Disulfiram; Dopamine; Humans; Methyltyrosines; Metronidazole; NAD; Norepinephrine; Schizophrenia; Tyrosine | 1977 |
The importance of monoamine metabolism for the pathology of the extrapyramidal system.
Topics: Aged; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Catechol Oxidase; Catecholamines; Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Kinetics; Methyltyrosines; Middle Aged; NAD; Parkinson Disease; Rats; Tritium; Tyrosine | 1969 |
Long-range nonradiative transfer of electronic excitation energy in proteins and polypeptides.
Topics: Adrenocorticotropic Hormone; Catalase; Chemical Phenomena; Chemistry, Physical; Coloring Agents; Copper; Dipeptides; Energy Transfer; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Hemoglobins; Indoles; Insulin; L-Lactate Dehydrogenase; Mathematics; Monoiodotyrosine; Myoglobin; NAD; Parathyroid Hormone; Peptides; Phenols; Phenylalanine; Phosphoric Acids; Picolines; Plant Proteins; Proteins; Pyridoxal Phosphate; Thyroxine; Transferrin; Tryptophan; Tyrosine | 1971 |
Evaluation of the chemiosmotic interpretation of active transport in bacterial membrane vesicles.
Topics: Benzenesulfonates; Biological Transport, Active; Carbon Radioisotopes; Cell Membrane; Cytochromes; Dinitrophenols; Escherichia coli; Kinetics; Lactose; Lysine; Mercury; NAD; Organoids; Organometallic Compounds; Oxygen Consumption; Potassium; Proline; Rubidium; Serine; Succinates; Tyrosine; Valinomycin | 1974 |
SOME ASPECTS OF STEROID HORMONE ACTION.
Topics: 17-Ketosteroids; Adenosine Triphosphatases; Amino Acid Oxidoreductases; Desoxycorticosterone; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Glucosephosphate Dehydrogenase; Hydrocortisone; Metabolism; NAD; Oxidoreductases; Peroxidases; Pharmacology; Phosphotransferases; Progesterone; Proteins; Research; RNA; Steroids; Testosterone; Transaminases; Tyrosine | 1963 |
Spectrophotometric assays for monitoring tRNA aminoacylation and aminoacyl-tRNA hydrolysis reactions.
Topics: Adenosine Monophosphate; Aminoacyltransferases; Enzyme Assays; Escherichia coli; Gene Expression; Geobacillus stearothermophilus; Hydrolysis; Kinetics; Mycobacterium tuberculosis; NAD; Peptides, Cyclic; Recombinant Proteins; RNA, Transfer, Tyr; Sensitivity and Specificity; Spectrophotometry; Stereoisomerism; Transfer RNA Aminoacylation; Tyrosine; Tyrosine-tRNA Ligase | 2017 |
127 other study(ies) available for tyrosine and nad
Article | Year |
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Regulation of Chorismate mutase-prephenate dehydratase and prephenate dehydrogenase from alcaligenes eutrophus.
Topics: Alcaligenes; Cell-Free System; Chorismate Mutase; Enzyme Activation; Feedback; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; NAD; Oxidoreductases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Pyruvates; Temperature; Tryptophan; Tyrosine | 1976 |
On the nature of an intermediate that is formed during the enzymatic conversion of phenylalanine to tyrosine.
Topics: Binding Sites; Dihydropteridine Reductase; Enzyme Activation; Gels; Hydrogen-Ion Concentration; Kinetics; NAD; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Protein Binding; Spectrophotometry, Ultraviolet; Tyrosine | 1976 |
The catabolism of L-tyrosine by an Arthrobacter sp.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Hydroxyphenylpyruvate Dioxygenase; Arthrobacter; Cell-Free System; NAD; NADP; Oxygenases; Pyruvates; Stereoisomerism; Succinates; Tyrosine; Tyrosine Transaminase | 1977 |
Diphtheria toxin: the effect of nitration and reductive methylation on enzymatic activity and toxicity.
Topics: Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Diphtheria Toxin; Epitopes; Formaldehyde; HeLa Cells; Lysine; NAD; Oxidation-Reduction; Peptide Elongation Factors; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1977 |
Iodination of glyceraldehyde 3-phosphate dehydrogenase from Bacillus stearothermophilus.
Topics: Amino Acid Sequence; Apoenzymes; Electrophoresis; Geobacillus stearothermophilus; Glyceraldehyde-3-Phosphate Dehydrogenases; Histidine; Iodine; Monoiodotyrosine; NAD; Peptide Fragments; Protein Conformation; Spectrophotometry; Tyrosine | 1976 |
Allosteric enzyme-tRNA complexes as regulators of transcription or translation.
Topics: Chorismate Mutase; Chorismic Acid; Escherichia coli; Isomerases; NAD; Oxidoreductases; Polynucleotides; Prephenate Dehydrogenase; Protein Biosynthesis; RNA, Ribosomal; RNA, Transfer; Temperature; Transcription, Genetic; Tyrosine | 1976 |
Spectral evidence for tyrosine ionization linked to a conformational change in liver alcohol dehydrogenase ternary complexes.
Topics: Alcohol Oxidoreductases; Animals; Horses; Liver; NAD; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Tyrosine | 1979 |
Oxycytochrome P-450: its breakdown to superoxide for the formation of hydrogen peroxide.
Topics: Animals; Azides; Copper; Cytochrome c Group; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Isocitrate Dehydrogenase; Kinetics; Male; Microsomes, Liver; NAD; Oxidation-Reduction; Oxygen; Phenobarbital; Rats; Superoxides; Tyrosine | 1979 |
The ultraviolet fluorescence spectra of DPN-linked isocitrate dehydrogenase from bovine heart.
Topics: Animals; Binding Sites; Cattle; Hydrogen-Ion Concentration; Isocitrate Dehydrogenase; Myocardium; NAD; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1975 |
Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora. III. Inactivation by nitration of a tyrosine residue involved in coenzyme binding.
Topics: Amino Acid Sequence; Binding Sites; Glutamate Dehydrogenase; Kinetics; Ligands; Methane; NAD; NADP; Neurospora; Peptide Fragments; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1975 |
A possible mechanism for the increase in brain tyrosine levels induced by cyanide in mice.
Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Cyanides; Glutamate Dehydrogenase; Liver; Male; Mice; Mice, Inbred Strains; NAD; Potassium Cyanide; Tyrosine; Tyrosine Transaminase | 1992 |
Development and validation of a robust specific enzyme mediated assay for phenylalanine in serum.
Topics: Amino Acid Oxidoreductases; Chromatography, High Pressure Liquid; Clinical Enzyme Tests; Colorimetry; Humans; Hydrogen-Ion Concentration; Kinetics; NAD; Phenylalanine; Reproducibility of Results; Tetrazolium Salts; Tyrosine | 1992 |
Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin.
Topics: Adenine; Adenosine; Amino Acid Sequence; Azides; Binding Sites; Binding, Competitive; Diphtheria Toxin; Models, Molecular; Molecular Sequence Data; Molecular Weight; NAD; Peptide Fragments; Tyrosine | 1991 |
7-Tetrahydrobiopterin is an uncoupled cofactor for rat hepatic phenylalanine hydroxylase.
Topics: Animals; Biopterins; Hydrogen Peroxide; Hydroxylation; Kinetics; Liver; NAD; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Tyrosine | 1991 |
Effect of GTP gamma S on insulin binding and tyrosine phosphorylation in liver membranes and L6 muscle cells.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Membrane; Cell Membrane Permeability; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Insulin; Kinetics; Liver; Male; Muscles; NAD; Phosphorylation; Rats; Rats, Inbred Strains; Receptor, Insulin; Thionucleotides; Tyrosine | 1990 |
A single cyclohexadienyl dehydrogenase specifies the prephenate dehydrogenase and arogenate dehydrogenase components of the dual pathways to L-tyrosine in Pseudomonas aeruginosa.
Topics: Amino Acids, Dicarboxylic; Catalysis; Cyclohexanecarboxylic Acids; Cyclohexenes; Macromolecular Substances; Molecular Weight; NAD; Oxidoreductases; Prephenate Dehydrogenase; Pseudomonas aeruginosa; Tyrosine | 1990 |
The effect of thyroxine and related compounds on the aerobic myeloperoxidase--catalysed oxidation of NADH.
Topics: Aerobiosis; Catalysis; Humans; NAD; Oxidation-Reduction; Peroxidase; Spectrophotometry, Ultraviolet; Thyronines; Thyroxine; Tyrosine | 1988 |
Fluorescence spectra of NADH/NAD, kynurenine, tryptophan, and tyrosine.
Topics: Kynurenine; NAD; Oxidation-Reduction; Oxidoreductases; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1988 |
Evidence for the existence of a tyrosyl residue in the nicotinamide adenine dinucleotide binding site of chicken liver xanthine dehydrogenase.
Topics: Animals; Binding Sites; Chickens; Ketone Oxidoreductases; Kinetics; Liver; NAD; Protein Binding; Spectrophotometry; Tyrosine; Xanthine Dehydrogenase | 1987 |
Chorismate mutase-prephenate dehydrogenase from Escherichia coli: cooperative effects and inhibition by L-tyrosine.
Topics: Adamantane; Chorismic Acid; Escherichia coli; Kinetics; Mathematics; NAD; Oxidoreductases; Prephenate Dehydrogenase; Serum Albumin, Bovine; Tyrosine | 1985 |
Effect of dinitrophenyl modification on oxidation-reduction of glutathione reductase from yeast.
Topics: Binding Sites; Candida; Circular Dichroism; Dinitrofluorobenzene; Glutathione Reductase; NAD; NADP; Nitrobenzenes; Oxidation-Reduction; Spectrophotometry; Tyrosine | 1985 |
Spectrophotometric determination of some peptidases.
Topics: Amino Acid Oxidoreductases; Isoleucine; Leucine; Methionine; Methods; Microchemistry; NAD; Peptide Hydrolases; Peroxidases; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
On the role of amino groups in the structure and function of glutamate dehydrogenase. II. Effect of acetylation on molecular properties.
Topics: Acetates; Adenine Nucleotides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Kinetics; Liver; Molecular Weight; NAD; Sulfhydryl Compounds; Tyrosine; Ultracentrifugation | 1966 |
[Further experimental studies on the catecholamine metabolism in extrapyramidal diseases (Parkinson and chorea syndromes)].
Topics: Aged; Carboxy-Lyases; Catecholamines; Chorea; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Middle Aged; NAD; Oxidoreductases; Parkinson Disease; Phenylalanine; Tyrosine | 1967 |
Fluorescence of D-glyceraldehyde-3-phosphate dehydrogenase-substrate complexes.
Topics: Acetone; Animals; Binding Sites; Charcoal; Fluorescence; Glyceraldehyde; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerolphosphate Dehydrogenase; Glycerophosphates; Hydrogen-Ion Concentration; Iodoacetates; Methylation; Muscles; NAD; Phosphates; Protein Binding; Rabbits; Sulfhydryl Compounds; Tryptophan; Tyrosine; Yeasts | 1968 |
The effect of glucagon and insulin on the prothrombin response to coumarin anticoagulants.
Topics: Acenocoumarol; Animals; Glucagon; Guinea Pigs; Insulin, Long-Acting; NAD; Prothrombin; Prothrombin Time; Tryptophan; Tyrosine | 1968 |
Feedback inhibition of glutamine synthetase of Neurospora crassa by nicotinamide-adenine dinucleotide.
Topics: Adenosine Triphosphate; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Feedback; Glutamates; Glutamine; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Ligases; NAD; Neurospora; ortho-Aminobenzoates; Phenylalanine; Quaternary Ammonium Compounds; Tryptophan; Tyrosine | 1968 |
Nature and mechanisms of oxygenases.
Topics: Amino Acids; Bacteria; Biotransformation; Catalysis; Catechol Oxidase; Chemical Phenomena; Chemistry; Cholesterol; Collagen; Dihydroxyphenylalanine; Flavin-Adenine Dinucleotide; Hydroxyproline; Lysine; NAD; Oxygen; Oxygenases; Phenylalanine; Plants; Prostaglandins; Squalene; Tryptophan Oxygenase; Tyrosine | 1969 |
Phosphorescence and energy transfer in enzymes.
Topics: Alcohol Oxidoreductases; Amylases; Animals; Aspergillus; Bacillus subtilis; Carboxypeptidases; Cattle; Chymotrypsin; Cold Temperature; Energy Transfer; Enzymes; Luminescent Measurements; Methods; Muramidase; NAD; Pancreas; Papain; Pepsin A; Ribonucleases; Saccharomyces; Spectrum Analysis; Tryptophan; Tyrosine | 1969 |
Ruby laser damage and pigmentation of the iris.
Topics: Animals; Autoradiography; Guinea Pigs; Haplorhini; Iris; Lasers; NAD; Pigmentation; Protein Biosynthesis; Rabbits; Tritium; Tyrosine | 1969 |
Activity of the phenylalanine hydroxylating system in liver of newborn, suckling and adult rats.
Topics: Aging; Aldehydes; Animals; Animals, Newborn; Body Weight; Carbon Isotopes; Female; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; Organ Size; Phenylalanine; Proteins; Rats; Tyrosine | 1969 |
The enzymology of prephenate dehydrogenase in Bacillus subtilis.
Topics: Bacillus subtilis; Chemical Phenomena; Chemistry; Cyclohexanes; Enzyme Repression; Fluorometry; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutation; NAD; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Protein Binding; Pyruvates; Stereoisomerism; Tryptophan; Tyrosine | 1970 |
Myeloperoxidase of the leukocyte of normal blood. II. The oxidation-reduction reaction mechanism of the myeloperoxidase system.
Topics: Adrenochrome; Animals; Blood Platelets; Cytochromes; Dihydroxyphenylalanine; Dopamine; Epinephrine; Erythrocytes; Free Radicals; Hydrogen Peroxide; Iron; Leukocytes; Models, Chemical; NAD; Norepinephrine; Oxidation-Reduction; Oxidoreductases; Oxygen; Peroxidases; Phenols; Phenylalanine; Spectrophotometry; Swine; Time Factors; Tyrosine; Ultraviolet Rays | 1970 |
Role of tyrosine in the substrate binding site of mitochondrial L-malate dehydrogenase from bovine heart muscle.
Topics: Acetates; Acylation; Animals; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxylic Acids; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dicarboxylic Acids; Enzyme Activation; Fumarates; Glutamates; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Kinetics; Malate Dehydrogenase; Malates; Mercuribenzoates; Methane; Mitochondria, Muscle; Myocardium; NAD; Spectrophotometry; Sulfates; Sulfonic Acids; Tyrosine | 1971 |
The inactivation of phenylalanine hydroxylase by 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine and the aerobic oxidation of the latter. The effects of catalase, dithiothreitol and reduced nicotinamide-adenine dinucleotide.
Topics: Air; Animals; Catalase; Coenzymes; Dithiothreitol; Hydrogen Peroxide; Liver; Liver Extracts; Mice; Mixed Function Oxygenases; NAD; Oxidation-Reduction; Peroxides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Tyrosine | 1971 |
Glyceraldehyde 3-phosphate dehydrogenase of Bacillus stearothermophilus. Kinetics and physicochemical studies.
Topics: Bacillus; Chemical Phenomena; Chemistry; Circular Dichroism; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Models, Chemical; NAD; Spectrometry, Fluorescence; Temperature; Tyrosine; Urea | 1973 |
The use of isocyanides for the immobilization of biological molecules.
Topics: Acrylamides; Adenosine Monophosphate; Biotin; Chromatography, Gel; Chymotrypsin; Cyanides; Esters; Humans; Hydrogen-Ion Concentration; Leucine; Methods; Molecular Weight; NAD; Penicillanic Acid; Penicillin G; Phenylalanine; Protein Binding; RNA; Serum Albumin; Temperature; Tyrosine | 1973 |
The degradation of L-histidine in the rat. The formation of imidazolylpyruvate, imidazolyl-lactate and imidazolylpropionate.
Topics: Alcohol Oxidoreductases; Animals; Chromatography, DEAE-Cellulose; Histidine; Imidazoles; Intestines; Ketoglutaric Acids; L-Lactate Dehydrogenase; Lactates; Mitochondria, Liver; Molecular Weight; NAD; Phenylalanine; Propionates; Pyruvates; Rats; Transaminases; Tyrosine | 1973 |
Proceedings: Binding constants of nicotinamide nucleotides to native and modified (tyrosine residue) lactate dehydrogenase.
Topics: Binding Sites; Hydrogen-Ion Concentration; In Vitro Techniques; L-Lactate Dehydrogenase; NAD; Protein Binding; Protein Conformation; Tyrosine | 1974 |
Deiodination of iodinated amino acids by pig thyroid micrsomes.
Topics: Amino Acids; Amobarbital; Animals; Antimycin A; Chromatography; Electron Transport Complex IV; Hydrogen-Ion Concentration; Iodine; Iodine Isotopes; Microsomes; NAD; NADP; Oxygen; Peroxidases; Swine; Thyroid Gland; Tyrosine | 1967 |
Effect of nicotinamide in vivo on thyroid pyridine nucleotides and radioiodine metabolism.
Topics: Animals; Diiodotyrosine; Iodides; Iodine Isotopes; Iodoproteins; Male; NAD; NADP; Niacinamide; Rats; Stimulation, Chemical; Thyroid Gland; Thyroxine; Triiodothyronine; Tyrosine | 1968 |
Formation of meta-tyrosine form L-phenylalanine by beef adrenal medulla. A new biosynthetic route to catecholamines.
Topics: Adrenal Medulla; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Catecholamines; Cattle; Chromatography, Ion Exchange; Cresols; Dihydroxyphenylalanine; Female; Hydroxylamines; Iron; Kinetics; Methyltyrosines; Monoiodotyrosine; NAD; Phenols; Phenylalanine; Pteridines; Rats; Stereoisomerism; Tyrosine; Tyrosine 3-Monooxygenase | 1971 |
[Hydroxylation of phenylalanine by Hydrogenomonas eutropha H 16].
Topics: Cell-Free System; Chromatography, Gel; Enzyme Induction; Mixed Function Oxygenases; NAD; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pseudomonas; Tryptophan; Tyrosine | 1972 |
The binding of tyrosine and NAD+ to chorismate mutase/prephenate dehydrogenase from Escherichia coli K12 and the effects of these ligands on the activity and self-association of the enzyme. Analysis in terms of a model.
Topics: Escherichia coli; Kinetics; Macromolecular Substances; Mathematics; NAD; Oxidoreductases; Prephenate Dehydrogenase; Protein Binding; Tyrosine | 1983 |
Identification of the lysine and tyrosine peptides labeled by 5'-p-fluorosulfonylbenzoyladenosine in the NADH inhibitory site of glutamate dehydrogenase.
Topics: Adenosine; Affinity Labels; Amino Acids; Animals; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Lysine; NAD; Oxidation-Reduction; Tyrosine | 1984 |
Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by ethoxyformic anhydride.
Topics: Animals; Cattle; Diethyl Pyrocarbonate; Electron Transport; Formates; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Meperidine; Mitochondria, Heart; NAD; NAD(P)H Dehydrogenase (Quinone); NADH, NADPH Oxidoreductases; Quinone Reductases; Tyrosine | 1984 |
Lysine and tyrosine in the NADH inhibitory site of bovine liver glutamate dehydrogenase.
Topics: Adenosine; Amino Acids; Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Lysine; NAD; Oxidation-Reduction; Protein Binding; Tyrosine | 1981 |
The radiation inactivation of glutamate dehydrogenase.
Topics: Binding Sites; Cysteine; Electrons; Enzyme Activation; Free Radicals; Gamma Rays; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; NAD; Pulse Radiolysis; Tryptophan; Tyrosine | 1983 |
An NADH-coupled assay for femtogram or nanogram quantities of chymotrypsin.
Topics: Animals; Chymotrypsin; Fluorometry; Microchemistry; NAD; Rats; Spectrophotometry, Ultraviolet; Tyrosine | 1983 |
Characterization of the dihydropterin reductase activity of pig liver methylenetetrahydrofolate reductase.
Topics: Animals; Biopterins; Cell-Free System; Dihydropteridine Reductase; In Vitro Techniques; Liver; Methylenetetrahydrofolate Dehydrogenase (NADP); NAD; NADH, NADPH Oxidoreductases; NADP; Oxidoreductases; Quinones; Swine; Tetrahydrofolates; Tyrosine; Vitamin K | 1980 |
Slow structural changes shown by the 3-nitrotyrosine-237 residue in pig heart [Tyr(3NO2)237] lactate dehydrogenase.
Topics: Animals; Kinetics; L-Lactate Dehydrogenase; Myocardium; NAD; Oxamic Acid; Protein Conformation; Spectrophotometry; Swine; Temperature; Tyrosine | 1982 |
Arogenate (pretyrosine) pathway of tyrosine and phenylalanine biosynthesis in Pseudomonas aureofaciens ATCC 15926.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; NAD; NADP; Oxidoreductases; Phenylalanine; Prephenate Dehydrogenase; Pseudomonas; Tyrosine | 1982 |
Chemical modification and site-directed mutagenesis studies of rat 3-hydroxyisobutyrate dehydrogenase.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Rats; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1995 |
Roles of Arg231 and Tyr284 of Thermus thermophilus isocitrate dehydrogenase in the coenzyme specificity.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; DNA, Bacterial; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Thermus thermophilus; Tyrosine | 1994 |
Bacterial expression and site-directed mutagenesis of two critical residues (tyrosine-151 and lysine-155) of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.
Topics: Amino Acid Sequence; Base Sequence; Escherichia coli; Female; Gene Expression; Humans; Hydroxyprostaglandin Dehydrogenases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Placenta; Prostaglandins; Recombinant Proteins; Sequence Homology; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1994 |
Site-directed mutagenesis of tyrosine residues at nicotinamide nucleotide binding sites of Escherichia coli transhydrogenase.
Topics: Amino Acid Sequence; Binding Sites; Biological Transport, Active; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP Transhydrogenases; Structure-Activity Relationship; Tyrosine | 1993 |
Formation of a hydroxyl radical by the myeloperoxidase-NADH-oxygen system.
Topics: Aerobiosis; Catalase; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Kinetics; NAD; Oxygen; Peroxidase; Phenylalanine; Superoxide Dismutase; Tyrosine | 1993 |
Mutation of Tyr235 in the NAD(H)-binding subunit of the proton-translocating nicotinamide nucleotide transhydrogenase of Rhodospirillum rubrum affects the conformational dynamics of a mobile loop and lowers the catalytic activity of the enzyme.
Topics: Asparagine; Binding Sites; Biological Transport; Catalysis; Magnetic Resonance Spectroscopy; NAD; NADP Transhydrogenases; Phenylalanine; Protein Conformation; Rhodospirillum rubrum; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan; Tyrosine | 1996 |
Oxidative modification of nicotinamide nucleotide transhydrogenase in submitochondrial particles: effect of endogenous ubiquinol.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Blotting, Western; Cattle; Ferric Compounds; Kinetics; Lipid Peroxides; NAD; NADP; NADP Transhydrogenases; Nitrates; Oxidation-Reduction; Peptide Mapping; Stress, Physiological; Submitochondrial Particles; Tyrosine; Ubiquinone | 1996 |
Mutations at tyrosine-235 in the mobile loop region of domain I protein of transhydrogenase from Rhodospirillum rubrum strongly inhibit hydride transfer.
Topics: Hydrogen; Mutation; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Rhodospirillum rubrum; Tyrosine | 1997 |
Determination of L-phenylalanine based on an NADH-detecting biosensor.
Topics: Amino Acid Oxidoreductases; Benzoquinones; Biosensing Techniques; Carbon; Catechols; Electrochemistry; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; Mixed Function Oxygenases; Monophenol Monooxygenase; NAD; Phenylalanine; Tyrosine | 1998 |
Formation of a tyrosyl radical in xanthine oxidase.
Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Flavins; Free Radicals; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; NAD; Oxidation-Reduction; Tyrosine; Xanthine Oxidase | 1998 |
Aberrant neutrophil trafficking and metabolic oscillations in severe pyoderma gangrenosum.
Topics: Acetylglucosamine; Adolescent; Cell Movement; Cell Polarity; Female; Humans; Macrophage-1 Antigen; NAD; Neutrophils; Phosphorylation; Pyoderma Gangrenosum; Temperature; Tyrosine | 1998 |
Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Mutagenesis, Insertional; NAD; Phenylalanine; Serine; Tyrosine; UDPglucose 4-Epimerase; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose | 1998 |
Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
Topics: Amino Acid Sequence; Histidine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Mutagenesis, Site-Directed; NAD; Point Mutation; Progesterone Reductase; Recombinant Proteins; Steroid Isomerases; Tyrosine | 1998 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan | 1999 |
Role of interleukin-6 in a non-septic shock model induced by zymosan.
Topics: Animals; Antibodies, Monoclonal; Ascites; Ascitic Fluid; DNA Damage; Energy Metabolism; Injections, Intraperitoneal; Interleukin-6; Intestine, Small; Leukocyte Count; Lipid Peroxidation; Liver; Lung; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiple Organ Failure; NAD; Neutrophils; Nitrates; Nitrites; Oxidative Phosphorylation; Peritonitis; Peroxidase; Shock; Tyrosine; Zymosan | 1999 |
Roles of tyrosine 158 and lysine 165 in the catalytic mechanism of InhA, the enoyl-ACP reductase from Mycobacterium tuberculosis.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalysis; Circular Dichroism; Deuterium; Histidine; Kinetics; Lysine; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; NAD; Oxidoreductases; Peptide Fragments; Recombinant Proteins; Solvents; Tyrosine | 1999 |
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Metalloporphyrins; NAD; Nitrates; Peroxidase; Rats; Rats, Sprague-Dawley; Shock; Superoxide Dismutase; Tyrosine; Zymosan | 1999 |
Denitration of peroxynitrite-treated proteins by 'protein nitratases' from rat brain and heart.
Topics: Animals; beta-Fructofuranosidase; Blotting, Western; Brain; Brain Chemistry; Calcium; Dialysis; Enzymes; Flavin-Adenine Dinucleotide; Glutathione; Glutathione Transferase; Glycoside Hydrolases; Myocardium; NAD; NADP; Nitrates; Proteins; Rats; Serum Albumin, Bovine; Tissue Extracts; Tyrosine | 1999 |
Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.
Topics: Animals; Autoradiography; Brain; Cells, Cultured; DNA Damage; Enzyme Activation; Glutamic Acid; Immunohistochemistry; Kidney; Mice; Mice, Knockout; N-Methylaspartate; NAD; Nitric Oxide; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Proteins; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2000 |
Competition between C-terminal tyrosine and nicotinamide modulates pyridine nucleotide affinity and specificity in plant ferredoxin-NADP(+) reductase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Binding, Competitive; Chloroplasts; Ferredoxin-NADP Reductase; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; Niacinamide; Pisum sativum; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2000 |
Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.
Topics: Binding Sites; Crystallography, X-Ray; Dimerization; Humans; Hydrogen Bonding; Models, Molecular; NAD; Pichia; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Tyrosine; UDPglucose 4-Epimerase; Uridine Diphosphate; Uridine Diphosphate Glucose | 2000 |
Functional comparison of the NAD binding cleft of ADP-ribosylating toxins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cholera Toxin; Diphtheria Toxin; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Phenylalanine; Poly(ADP-ribose) Polymerases; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tyrosine | 2000 |
Reactions of peroxynitrite in the mitochondrial matrix.
Topics: Animals; Ascorbic Acid; Blotting, Western; Carbon Dioxide; Glutathione; Inhibitory Concentration 50; Kinetics; Mice; Mitochondria, Liver; NAD; Nitrates; Oxidation-Reduction; Spectrometry, Fluorescence; Superoxides; Tyrosine; Ubiquinone | 2000 |
NAD+-dependent DNA ligase encoded by a eukaryotic virus.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Base Sequence; Catalysis; Cysteine; DNA Ligases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; Gene Deletion; Genetic Vectors; Models, Biological; Molecular Sequence Data; Mutation; NAD; Phylogeny; Poxviridae; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Tyrosine; Zinc; Zinc Fingers | 2001 |
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
Topics: Animals; Benzamides; Enzyme Inhibitors; Immunohistochemistry; Interleukin-10; Interleukin-12; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocardium; NAD; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tissue Extracts; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase.
Topics: Catalytic Domain; Circular Dichroism; Escherichia coli; Glucose; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; NAD; Phosphotransferases (Phosphomutases); Threonine; Thymine Nucleotides; Tyrosine; UDPglucose 4-Epimerase; Xylose | 2001 |
Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation.
Topics: Animals; Brain; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Female; Heart; Hydrogen Peroxide; Immunoblotting; Liver; Mitochondria; Mitochondria, Heart; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Nitric Oxide; Oxidoreductases; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Succinate Cytochrome c Oxidoreductase; Succinate Dehydrogenase; Succinates; Superoxide Dismutase; Superoxides; Tyrosine | 2001 |
Effects of flavin-binding motif amino acid mutations in the NADH-cytochrome b5 reductase catalytic domain on protein stability and catalysis.
Topics: Amino Acid Motifs; Animals; Arginine; Binding Sites; Catalysis; Catalytic Domain; Circular Dichroism; Cytochrome Reductases; Cytochrome-B(5) Reductase; Enzyme Stability; Flavin-Adenine Dinucleotide; Kinetics; Models, Chemical; Mutation; NAD; Protein Binding; Protein Denaturation; Protein Structure, Tertiary; Serine; Swine; Tyrosine | 2001 |
The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Electrons; Fungal Proteins; Models, Molecular; Molecular Sequence Data; NAD; Neurospora crassa; Protein Binding; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Repressor Proteins; Sequence Homology, Amino Acid; Transcription Factors; Transcription, Genetic; Tyrosine; UDPglucose 4-Epimerase | 2001 |
Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; DNA Ligases; Dose-Response Relationship, Drug; Escherichia coli; Gene Deletion; Histidine; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutation; NAD; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Time Factors; Tyrosine | 2002 |
Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.
Topics: Alanine; Amino Acid Substitution; Ascorbic Acid; Binding Sites; Corynebacterium; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gluconates; Glycine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Phenylalanine; Recombinant Fusion Proteins; Sugar Alcohol Dehydrogenases; Thermodynamics; Tyrosine | 2002 |
Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; DNA, Complementary; Humans; In Vitro Techniques; Isocitrate Dehydrogenase; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; NAD; NADP; Protein Structure, Secondary; Rats; Sequence Homology, Amino Acid; Swine; Tyrosine | 2002 |
The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Astrocytes; Cells, Cultured; Cerebral Cortex; Coculture Techniques; DNA Fragmentation; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Glycoside Hydrolases; Mice; NAD; NADPH Oxidases; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tyrosine; Zinc | 2002 |
The catalytic mechanism of Drosophila alcohol dehydrogenase: evidence for a proton relay modulated by the coupled ionization of the active site Lysine/Tyrosine pair and a NAD+ ribose OH switch.
Topics: Alcohol Dehydrogenase; Animals; Binding Sites; Catalysis; Computer Simulation; Drosophila; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxides; Lysine; Models, Chemical; Models, Molecular; NAD; Oxidation-Reduction; Protein Binding; Protons; Substrate Specificity; Tyrosine; Water | 2003 |
[RECENT DATA ACQUIRED ON THE METABOLISM OF NUCLEIC ACIDS, THANKS TO THE USE OF RADIO-ISOTOPES. SPECIAL CONSIDERATIONS OF THE TIES BETWEEN NUCLEIC ACID METABOLISM AND PROTEIN METABOLISM].
Topics: Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Cell Nucleus; Centrifugation; Chromatography; DNA; Estradiol; Hepatectomy; Kidney; Leucine; Liver; NAD; Niacin; Niacinamide; Nucleotidases; Nucleotides; Phosphates; Phosphorus Isotopes; Poultry; Protein Deficiency; Proteins; Rats; Research; RNA; Tyrosine | 1963 |
INDUCED, SOLUBLE PHENYLALANINE HYDROXYLASE FROM PSEUDOMONAS SP. GROWN ON PHENYLALANINE OR TYROSINE.
Topics: Asparagine; Mixed Function Oxygenases; NAD; Phenylalanine; Phenylalanine Hydroxylase; Physiological Phenomena; Proteins; Pseudomonas; Research; Tyrosine | 1963 |
[TRIALS OF A NEW ANTIHYPERTENSIVE, ALPHA-METHYL-DOPA (ALDOMET) WITH SPECIAL REFERENCE TO CHANGES IN RETINAL BLOOD FLOW].
Topics: Angiotensins; Antihypertensive Agents; Blood Circulation; Blood Pressure; Blood Pressure Determination; Dopamine; Epinephrine; Hemodynamics; Methyldopa; NAD; Norepinephrine; Phenylalanine; Renin; Retinal Vessels; Serotonin; Tryptophan; Tyrosine | 1963 |
STUDIES OF PROTEIN AND BOUND COENZYME FLUORESCENCE OF LACTATE DEHYDROGENASES.
Topics: Animals; Cattle; Coenzymes; Fluorescence; Fluorometry; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Muscles; Myocardium; NAD; Poultry; Research; Spectrophotometry; Tryptophan; Tyrosine | 1964 |
ACTIVITY OF THREE TRANSAMINASES DURING SPONTANEOUS AND INDUCED METAMORPHOSIS IN RANA CATESBEIANA.
Topics: Alanine Transaminase; Animals; Anura; Aspartate Aminotransferases; Liver; Metamorphosis, Biological; NAD; Pharmacology; Rana catesbeiana; Ranidae; Research; Spectrophotometry; Thyroxine; Transaminases; Tyrosine | 1964 |
USE OF BUTYL ACETATE AS A SOLVENT FOR THE EXTRACTION OF TRICHLOROACETIC ACID.
Topics: Acetates; Adenosine Triphosphate; Carbon Isotopes; Ethers; Glucose; Hexosephosphates; Leucine; NAD; Phosphates; Pyruvates; Research; Solvents; Sorbitol; Trichloroacetic Acid; Tyrosine | 1964 |
SOLUBLE BETA-NADH (BETA-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE) OXIDASE SYSTEM IN THE YOUNG ROOT OF THE BROAD BEAN, VICIA FABA. I. PRELIMINARY INVESTIGATIONS.
Topics: Ascorbic Acid; Carbamates; Cobalt; Copper; Cresols; Cyanides; Cytochromes; Edetic Acid; Iron; Manganese; NAD; Nickel; Oxidoreductases; Oximes; Pharmacology; Phenols; Plants; Quinolines; Research; Spectrophotometry; Thiourea; Tyramine; Tyrosine; Vicia faba; Zinc | 1964 |
NONCOVALENT INTERACTIONS BETWEEN AMINO ACID SIDE CHAINS AND A COENZYME MODEL.
Topics: Amino Acids; Coenzymes; Fluorescence; Fluorometry; Histidine; Imidazoles; Indoles; Lysine; Methionine; NAD; Phenols; Phenylalanine; Pyridines; Research; Spectrum Analysis; Tyramine; Tyrosine | 1964 |
HEAVY-ATOM PERTURBATION, MOLECULAR COMPLEXING AND ACTIVITY OF THYROXINE.
Topics: Antifibrinolytic Agents; Benzoates; Chemical Phenomena; Chemistry; Flavin Mononucleotide; NAD; Naphthoquinones; Pyridines; Research; Riboflavin; Spectrophotometry; Thyroxine; Tyrosine; Vitamin K | 1965 |
PHENYLALANINE HYDROXYLATION BY PSEUDOMONAS SPECIES (ATCC 11299A).
Topics: Asparagine; Carbon Isotopes; Culture Media; Hydroxylation; Iron; Keto Acids; Metabolism; Mixed Function Oxygenases; NAD; Phenylalanine; Pseudomonas; Pterins; Radiometry; Research; Tyrosine | 1965 |
COLUMN-CHROMATOGRAPHIC SEPARATION OF A PEROXIDASE AND AN IODINASE IN SOLUBILIZED BEEF-THYROID PREPARATIONS.
Topics: Alkaloids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography; Glucose; Glucose Oxidase; Hydrogen Peroxide; Iodide Peroxidase; Manganese; NAD; Oxidoreductases; Pancreatic Extracts; Pancreatin; Peroxidase; Peroxidases; Phenols; Research; Sulfites; Thyroid Gland; Thyrotropin; Tyrosine | 1965 |
Acute ammonia intoxication induces an NMDA receptor-mediated increase in poly(ADP-ribose) polymerase level and NAD metabolism in nuclei of rat brain cells.
Topics: Amide Synthases; Ammonia; Animals; Brain; Brain Chemistry; Cell Nucleus; Male; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proteins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Superoxides; Tyrosine | 2004 |
A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
Topics: Animals; Arginine; Ascaris suum; Aspartic Acid; Catalytic Domain; Deuterium Exchange Measurement; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Models, Chemical; NAD; Phenylalanine; Spectrophotometry; Substrate Specificity; Tyrosine | 2005 |
How tyrosine phosphorylation affects the UDP-glucose dehydrogenase activity of Bacillus subtilis YwqF.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Molecular Sequence Data; Mutation; NAD; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine; Uridine Diphosphate Glucose Dehydrogenase | 2004 |
C-terminal tyrosine of ferredoxin-NADP+ reductase in hydride transfer processes with NAD(P)+/H.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anabaena; Crystallization; Ferredoxin-NADP Reductase; Hydrogen; Molecular Structure; NAD; NADP; Pisum sativum; Tyrosine | 2005 |
Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis.
Topics: Catalysis; Dihydroorotate Dehydrogenase; Dimerization; Electrochemistry; Electron Transport; Flavin Mononucleotide; Flavins; Lactococcus lactis; Lysine; Mutagenesis, Site-Directed; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Structure, Tertiary; Tyrosine | 2006 |
A single mutation at Tyr143 of human S-adenosylhomocysteine hydrolase renders the enzyme thermosensitive and affects the oxidation state of bound cofactor nicotinamide-adenine dinucleotide.
Topics: Adenosylhomocysteinase; Amino Acid Substitution; Catalysis; Cysteine; Dithiothreitol; Enzyme Stability; Escherichia coli; Hot Temperature; Humans; Hydrogen Bonding; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; Oxidation-Reduction; Protein Folding; Protein Structure, Quaternary; Recombinant Proteins; Reducing Agents; Structure-Activity Relationship; Tyrosine | 2006 |
Tyrosine-dependent oxidative DNA damage induced by carcinogenic tetranitromethane.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cattle; Chelating Agents; Copper; Deoxyguanosine; DNA; DNA Damage; Humans; Molecular Structure; NAD; Oxidation-Reduction; Peptides; Tetranitromethane; Tyrosine | 2006 |
Mutation of Tyr-218 to Phe in Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase: effects on bioelectronic interface performance.
Topics: Alcohol Oxidoreductases; Biosensing Techniques; Electrochemistry; Mutagenesis, Site-Directed; NAD; Phenylalanine; Thermoanaerobacter; Tyrosine | 2007 |
Protein nitration, PARP activation and NAD+ depletion may play a critical role in the pathogenesis of cyclophosphamide-induced hemorrhagic cystitis in the rat.
Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Cyclophosphamide; Cystitis; Hemorrhage; Immunoenzyme Techniques; Male; Malondialdehyde; NAD; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine; Urinary Bladder | 2009 |
Tyr-51 is the proton donor-acceptor for NAD(H)-dependent interconversion of xylose and xylitol by Candida tenuis xylose reductase (AKR2B5).
Topics: Alanine; Aldehyde Reductase; Amino Acid Substitution; Candida; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; NAD; Protons; Tyrosine; Xylitol; Xylose | 2008 |
Nitrosative stress, protein tyrosine nitration, PARP activation and NAD depletion in the kidneys of rats after single dose of cyclophosphamide.
Topics: Animals; Cyclophosphamide; DNA Damage; Down-Regulation; Enzyme Activation; Immunohistochemistry; Injections, Intraperitoneal; Kidney; Male; NAD; Nitrates; Nitrites; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Nitrogen Species; Superoxide Dismutase; Time Factors; Tyrosine | 2009 |
The crystal structure of Aquifex aeolicus prephenate dehydrogenase reveals the mode of tyrosine inhibition.
Topics: Bacteria; Catalysis; Catalytic Domain; Crystallography, X-Ray; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; Prephenate Dehydrogenase; Protein Conformation; Tyrosine | 2009 |
Contributions of active site residues to cofactor binding and catalysis of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.
Topics: Androsterone; Asparagine; Catalysis; Catalytic Domain; Fluorescence Polarization; Hydroxysteroid Dehydrogenases; Kinetics; Lysine; Mutation; NAD; Protein Binding; Tyrosine | 2010 |
Mechanism of glyceraldehyde-3-phosphate dehydrogenase inactivation by tyrosine nitration.
Topics: Animals; Biocatalysis; Crystallography, X-Ray; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Models, Molecular; NAD; Protein Binding; Protein Structure, Tertiary; Rabbits; Tyrosine | 2010 |
Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.
Topics: Apigenin; Calcium Signaling; Catechin; Cells, Cultured; Curcumin; Enzyme Activation; Flavanones; Flavonoids; Humans; Hydrolyzable Tannins; L-Lactate Dehydrogenase; NAD; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Phenols; Poly(ADP-ribose) Polymerases; Polyphenols; Quinolinic Acid; Tyrosine | 2010 |
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide.
Topics: Azo Compounds; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Hot Temperature; Kinetics; Mesalamine; Mutagenesis, Site-Directed; NAD; NADH, NADPH Oxidoreductases; Nitroreductases; Phenylhydrazines; Protein Folding; Pseudomonas aeruginosa; Tyrosine | 2010 |
Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Glycolysis; Homeostasis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Mice; Mice, Nude; Mitochondria; NAD; Neoplasms; Oxidation-Reduction; Phosphorylation; Receptor, Fibroblast Growth Factor, Type 1; Tyrosine | 2011 |
Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin.
Topics: Aconitate Hydratase; Adenine Nucleotides; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Chromatography, High Pressure Liquid; Coenzyme A; Disease Models, Animal; Electroencephalography; Epilepsy; Fumarate Hydratase; Glutathione; Glutathione Disulfide; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NAD; Oxidative Stress; Superoxide Dismutase; Tyrosine | 2012 |
Synthesis, characterization, and electrochemical applications of carbon nanoparticles derived from castor oil soot.
Topics: Ascorbic Acid; Carbon; Castor Oil; Dopamine; Electrochemistry; Electrodes; Microscopy, Electron, Transmission; NAD; Nanoparticles; Oxidation-Reduction; Oxygen; Photoelectron Spectroscopy; Serotonin; Soot; Spectroscopy, Fourier Transform Infrared; Tyrosine; Uric Acid | 2012 |
A single tyrosine hydroxyl group almost entirely controls the NADPH specificity of Plasmodium falciparum ferredoxin-NADP+ reductase.
Topics: Amino Acid Substitution; Binding Sites; Coenzymes; Ferredoxin-NADP Reductase; Kinetics; NAD; NADP; Plasmodium falciparum; Substrate Specificity; Tyrosine | 2012 |
Identification of Tyr241 as a key catalytic base in the family 4 glycoside hydrolase BglT from Thermotoga maritima.
Topics: Amino Acid Substitution; Catalysis; Glucosidases; Hydrogen-Ion Concentration; Kinetics; NAD; Thermotoga maritima; Tyrosine | 2012 |
Fluorescence spectral diagnosis of malaria: a preliminary study.
Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Female; Flavin-Adenine Dinucleotide; Humans; Malaria; Male; NAD; Porphyrins; Sensitivity and Specificity; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Young Adult | 2014 |
PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy.
Topics: Animals; Benzamides; Constriction, Pathologic; Cyclooxygenase 2; Hyperalgesia; Inflammation; Male; NAD; Neuritis; Neuroprotective Agents; Oxidative Stress; Pain Measurement; Peripheral Nervous System Diseases; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Sensation; Tyrosine; Walking | 2016 |
Tyrosine phosphorylation of dihydrolipoamide dehydrogenase as a potential cadmium target and its inhibitory role in regulating mouse sperm motility.
Topics: Adenosine Triphosphate; Animals; Cadmium; Dihydrolipoamide Dehydrogenase; Immunoprecipitation; Male; Mice; NAD; Phosphorylation; Serum Albumin, Bovine; Sperm Capacitation; Sperm Motility; Spermatozoa; Tyrosine | 2016 |
Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase.
Topics: 3-Hydroxybutyric Acid; Alcaligenes faecalis; Amino Acid Motifs; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Gene Expression; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Hydroxybutyrate Dehydrogenase; Malonates; Methylmalonic Acid; Models, Molecular; NAD; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Subunits; Recombinant Proteins; Substrate Specificity; Tyrosine | 2016 |
Role of the Tyr270 residue in 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti.
Topics: Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Hydrogen Bonding; Kinetics; Mesorhizobium; Mixed Function Oxygenases; Models, Molecular; NAD; Nicotinic Acids; Oxidation-Reduction; Oxygen; Protein Interaction Domains and Motifs; Tyrosine | 2017 |
Biochemical characterization of TyrA enzymes from Ignicoccus hospitalis and Haemophilus influenzae: A comparative study of the bifunctional and monofunctional dehydrogenase forms.
Topics: Amino Acid Sequence; Bacterial Proteins; Chorismate Mutase; Desulfurococcaceae; Escherichia coli; Haemophilus influenzae; Histidine; Multienzyme Complexes; NAD; NADP; Prephenate Dehydrogenase; Tyrosine | 2017 |
DFT-based prediction of reactivity of short-chain alcohol dehydrogenase.
Topics: Alcohols; Catalysis; Cluster Analysis; Hydrogen-Ion Concentration; Ketones; Kinetics; Lysine; Molecular Docking Simulation; NAD; Oxidation-Reduction; Oxidoreductases; Quantum Theory; Rhodocyclaceae; Stereoisomerism; Tyrosine | 2017 |
A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5.
Topics: Animals; Crystallography, X-Ray; Humans; Hydrolysis; Mice; Models, Molecular; NAD; Phosphoric Diester Hydrolases; Pyrophosphatases; Recombinant Proteins; Tyrosine | 2017 |
Site-specific observation of the conformational change of a protein with
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); NAD; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Signal Transduction; Tyrosine | 2019 |