Compounds > tyrosine

tyrosine and n-formylmethionine leucyl-phenylalanine

tyrosine has been researched along with n-formylmethionine leucyl-phenylalanine in 94 studies

Research

Studies (94)

TimeframeStudies, this research(%)All Research%
pre-19909 (9.57)18.7374
1990's56 (59.57)18.2507
2000's29 (30.85)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inazu, T; Nakagawara, G; Ohta, S; Taniguchi, T; Yamamura, H1
Becker, EL; Gomez-Cambronero, J; Gomez-Cambronero, TM; Huang, CK; Sha'afi, RI; Waterman, WH1
Matter, WF; Vlahos, CJ1
Gaudry, M; Gilbert, C; Naccache, PH1
Beaulieu, AD; McColl, SR; Paquin, R; Rathanaswami, P1
Bonser, RW; Garland, LG; Hudson, AT; Randall, RW; Spacey, GD; Thompson, NT; Uings, IJ1
Hata, D; Higashi, H; Hosoi, S; Kusunoki, T; Mayumi, M; Mikawa, H; Sugie, K1
Buschauer, A; Höer, A; Offermanns, S; Schunack, W; Seifert, R1
Furuya, W; Grinstein, S1
Akimaru, K; Inoue, M; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T1
Caon, AC; Gaudry, M; Gilbert, C; Lille, S; Naccache, PH1
Berkow, RL1
Kantorski, J; Tchórzewski, H1
Berkow, RL; Dodson, RW1
Bonak, V; Casnellie, JE; Huang, CK; Laramee, GR1
Caon, AC; DiPersio, JF; Ho, P; McColl, SR; Naccache, PH1
Bonak, VA; Caon, AC; Gaudry, M; Gilbert, C; Huang, CK; McColl, SR; Naccache, PH; Umezawa, K1
Bonak, VA; Casnellie, JE; Gomez-Cambronero, J; Huang, CK; Sha'afi, RI; Shiraishi, T; Wang, E1
Broom, MF; Butt, TJ; Chadwick, VS; Ferry, DM; Hunter, J1
Nath, J; Powledge, A; Wright, DG1
Gallin, JI; Nath, J3
Casnellie, JE; Huang, CK; Laramee, GR1
Flavin, M; Nath, J; Schiffmann, E1
Flavin, M; Gallin, JI; Nath, J1
Klebanoff, SJ; Ledbetter, JA; Liles, WC; Waltersdorph, AW2
Grünbaum, L; Hagelüken, A; Höer, A; Höer, D; Offermanns, S; Schultz, G; Schunack, W; Schwaner, I; Seifert, R; Zingel, V1
Caon, AC; Liao, NW; Malawista, SE; McColl, SR; Naccache, PH; Roberge, CJ; Rollet, E1
Berton, G; Fumagalli, L; Laudanna, C; Sorio, C1
Anderson, DC; Brown, EJ; Graham, IL; Holers, VM1
Garcia-Welsh, A; Laskin, DL; Laskin, JD; Molloy, CJ1
Bates, ME; Busse, WW; Kita, H; Nagata, M; Sedgwick, JB1
Hall, FL; O'Neill, K; Torres, M1
Edashige, K; Sato, EF; Takehara, Y; Utsumi, K; Watanabe, Y1
Kobuchi, H; Kurashige, T; Minakami, K; Miyahara, M; Utsumi, K; Watanabe, Y1
Bator, JM; Jean, N; Kubes, P; Liao, NW; McColl, SR; Naccache, PH1
Donini, M; Dusi, S; Rossi, F1
Connelly, PA; Farrell, CA; Richard, S; Shaw, AS; Showell, HJ1
Edberg, JC; Kimberly, RP1
Azuma, EK; Kitagawa, S; Mizoguchi, H; Saito, M; Takaku, F; Umezawa, K; Yuo, A1
Chan, CK; Downey, GP; Fialkow, L; Grinstein, S1
Bianchini, L; Grinstein, S; Todderud, G1
Nath, J; Rothwell, SW; Wright, DG1
Gaehtgens, P; Ley, K; Offermanns, S; Walzog, B; Zakrzewicz, A1
Torres, M; Ye, RD1
Hallett, MB; Lloyds, D; Neville, N1
de Médicis, R; Gaudry, M; Gilbert, C; Lussier, A; Malawista, SE; Naccache, PH; Poubelle, PE; Roberge, CJ1
Donini, M; Dusi, S; Rossi, F; Wientjes, F1
Furuya, W; Grinstein, S; Krump, E; Pelech, SL; Sanghera, JS1
Kodama, H; Sagara, Y; Sugahara, K; Watanabe, Y; Zhang, J1
Battaglia, E; Brizzi, MF; Camussi, G; Montrucchio, G; Pegoraro, L; Rosso, A; Strippoli, P1
Banno, Y; Nozawa, Y; Takemura, OS1
Ito, O; Kodama, H; Masuoka, N; Sagara, Y; Ubuka, T; Zhang, J; Zhang, M1
Fernandez, R; Suchard, SJ1
Katagiri, Y; Nakamura, M; Nakashima, S; Nozawa, Y1
Duprè, S; Fontana, M; Hashimoto, K; Kodama, H; Sagara, Y; Sugahara, K; Zhang, J1
Bourgoin, S; Harbour, D; Houle, MG; Marcil, J; Naccache, PH1
Jutila, KL; Nelson, LK; Quinn, MT; Rohn, TT; Sipes, KM; Swain, SD1
Hajjar, JJ; Molski, TF; Nagarkatti, D; Sha'afi, RI; Syrbu, SI; Waterman, WH1
Nibbering, PH; Seijmonsbergen, E; van den Broek, PJ; van Furth, R; Visser, LG1
Kodama, H; Sagara, Y; Spirito, A; Sugahara, K; Zhang, J; Zhang, M1
Abe, K; Akiyama, J; Horton, AA; Kanno, T; Yabuki, M; Yasuda, T1
Bourgoin, S; Houle, MG; Naccache, PH1
De Nardin, E; Hishita, T; Lala, A; Miura, Y; Tohyama, K; Tohyama, Y; Uchiyama, T; Yamamura, H; Yoshida, Y1
Fiore, S; Kang, Y; Taddeo, B; Varai, G; Varga, J1
Caldwell, RB; Catravas, JD; Ehrhart, IC; Gu, X; Parkerson, JB; Theodorakis, MJ; Zou, L1
Asaka, Y; Kodama, H; Lu, HW; Manabe, M; Masuoka, N; Sagara, Y; Sugahara, K1
Fernandez, R; Hirschl, RB; Sarma, V; Ward, PA; Younger, JG; Younkin, E1
Feng, X; Kodama, H; Lu, H; Lu, J; Ma, D; Manabe, M; Sagara, Y; Sugahara, K; Sun, Q1
Barabé, F; Bourgoin, SG; Fernandes, MJ; Naccache, PH; Paré, G1
Gilbert, C; Naccache, PH; Rollet-Labelle, E1
Lachance, G; Levasseur, S; Naccache, PH1
Chen, G; Kodama, H; Lu, H; Lu, J; Manabe, M; Sagara, Y; Yamashita, K; Yokoyama, T1
Chen, G; Kodama, H; Lu, H; Manabe, M; Meng, Z; Wang, C; Xu, S; Yamashita, K1
Chen, G; Kodama, H; Lu, H; Manabe, M; Wang, C; Yamashita, K1
Aiboshi, J; Ambruso, DR; Bannerjee, A; Barnett, CC; Bjornsen, AJ; Elzi, DJ; England, KM; Hamiel, C; Harbeck, RJ; Kelher, M; McLaughlin-Malaxecheberria, N; Musters, RJ; Paterson, AJ; Silliman, CC; Wyman, TH1
Prange, P; Schymeinsky, J; Walzog, B; Willeke, T; Zahler, S1
Chen, G; Kitaoka, N; Kodama, H; Lu, H; Manabe, M; Sagara, Y; Song, S; Wang, Z; Xu, S1
Ambruso, DR; Anderson, SM; Elzi, DJ; Kelher, MR; Paterson, AJ; Silliman, CC; Thurman, GW1
Antunes, E; De Nucci, G; Marcondes, S; Moreira, J; Thomazzi, SM1
Inanami, O; Kuwabara, M; Nagahata, H; Yamamori, T1
Bredetean, O; Garcia, A; Kunapuli, SP; Meshki, J; Tuluc, F1
Bourgoin, SG; Burelout, C; Levasseur, S; Naccache, PH; Simard, S; Thibault, N1
Caselli, G; Ferrari, F; Makovec, F; Mennuni, L; Zanelli, T1
Kammerer, R; Klaile, E; Lucka, L; Müller, MM; Obrink, B; Reutter, W; Scheffrahn, I; Singer, BB1
Bokoch, GM; Zhao, T1
Chen, YL; Kuan, YH; Lin, RH; Tsao, LT; Tzeng, CC; Wang, JP1
Bühring, HJ; Chin, A; Liu, Y; Parkos, CA; Soto, I; Tong, Q; Wu, T; Zen, K1
Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K1
Chen, YS; Hsu, MF; Huang, LJ; Kuo, SC; Tsao, LT; Wang, JP1
Desaulniers, P; Gilbert, C; Marois, S; Naccache, PH; Paré, G; Popa-Nita, O1
Kodama, H; Liu, G; Manabe, M; Masuoka, N; Yamashita, K; Zhang, J1

Reviews

2 review(s) available for tyrosine and n-formylmethionine leucyl-phenylalanine

ArticleYear
Effect of vitamin C on tubulin tyrosinolation in polymorphonuclear leukocytes.
    Annals of the New York Academy of Sciences, 1987, Volume: 498

    Topics: Ascorbic Acid; Chediak-Higashi Syndrome; Cysteine; Dithiothreitol; Glutathione; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Protein Processing, Post-Translational; Tubulin; Tyrosine

1987
Modulation of tubulin tyrosinolation in human polymorphonuclear leukocytes (PMM).
    Kroc Foundation series, 1984, Volume: 16

    Topics: Anaerobiosis; Antioxidants; Ascorbic Acid; Carboxypeptidases; Chediak-Higashi Syndrome; Cyclohexanones; Diamide; Granulomatous Disease, Chronic; Humans; Methylene Blue; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peptide Synthases; Protein Processing, Post-Translational; Tubulin; Tyrosine

1984

Other Studies

92 other study(ies) available for tyrosine and n-formylmethionine leucyl-phenylalanine

ArticleYear
Protein-tyrosine phosphorylations induced by concanavalin A and N-formyl-methionyl-leucyl-phenylalanine in human neutrophils.
    European journal of biochemistry, 1992, Jun-15, Volume: 206, Issue:3

    Topics: Blood Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Concanavalin A; Humans; Immunoblotting; Kinetics; Molecular Weight; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Protein Kinases; Tyrosine; Virulence Factors, Bordetella

1992
Granulocyte-macrophage colony-stimulating factor-induced protein tyrosine phosphorylation of microtubule-associated protein kinase in human neutrophils.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-15, Volume: 89, Issue:16

    Topics: Amino Acid Sequence; Antibodies; Blood Proteins; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phosphoproteins; Phosphorylation; Protein Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tyrosine

1992
Signal transduction in neutrophil activation. Phosphatidylinositol 3-kinase is stimulated without tyrosine phosphorylation.
    FEBS letters, 1992, Sep-14, Volume: 309, Issue:3

    Topics: Blotting, Western; Chromatography, High Pressure Liquid; Enzyme Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases; Signal Transduction; Tyrosine

1992
Rapid priming of calcium mobilization and superoxide anion production in human neutrophils by substimulatory concentrations of phorbol esters: a novel role for protein kinase C and tyrosine phosphorylation in the up-modulation of signal transduction.
    Cellular signalling, 1992, Volume: 4, Issue:5

    Topics: Adult; Calcium; Humans; Hydroquinones; In Vitro Techniques; Indoles; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Superoxides; Tyrosine; Up-Regulation

1992
Nuclear signaling in human neutrophils. Stimulation of RNA synthesis is a response to a limited number of proinflammatory agonists.
    The Journal of biological chemistry, 1992, Jan-05, Volume: 267, Issue:1

    Topics: Cell Nucleus; Dactinomycin; Electrophoresis, Gel, Two-Dimensional; Fluorometry; Granulocyte-Macrophage Colony-Stimulating Factor; GTP-Binding Proteins; Humans; In Vitro Techniques; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; RNA; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine

1992
Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil.
    The Biochemical journal, 1992, Feb-01, Volume: 281 ( Pt 3)

    Topics: Enzyme Activation; Humans; Indoles; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Type C Phospholipases; Tyrosine

1992
Tyrosine phosphorylation and its possible role in superoxide production by human neutrophils stimulated with FMLP and IgG.
    Biochemical and biophysical research communications, 1992, Mar-16, Volume: 183, Issue:2

    Topics: Humans; Immunoglobulin G; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotyrosine; Protein-Tyrosine Kinases; Superoxides; Tyrosine

1992
Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue.
    Molecular pharmacology, 1992, Volume: 42, Issue:2

    Topics: Betahistine; Bucladesine; Calcium; Cations; Cell Differentiation; Cytosol; Glucuronidase; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Ion Channels; Leukemia, Experimental; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Receptors, Histamine H1; Secretory Rate; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella

1992
Chemoattractant-induced tyrosine phosphorylation and activation of microtubule-associated protein kinase in human neutrophils.
    The Journal of biological chemistry, 1992, Sep-05, Volume: 267, Issue:25

    Topics: Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Tyrosine

1992
Role of tyrosyl phosphorylation in neutrophil priming by tumor necrosis factor-alpha and granulocyte colony stimulating factor.
    Archives of biochemistry and biophysics, 1992, Nov-01, Volume: 298, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Blotting, Western; Cell Membrane; Cytosol; Genistein; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Isoflavones; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine

1992
Evidence for the involvement of tyrosine kinases in the locomotory responses of human neutrophils.
    Journal of leukocyte biology, 1992, Volume: 51, Issue:2

    Topics: Cell Adhesion; Chemotaxis, Leukocyte; Humans; Hydroquinones; In Vitro Techniques; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine

1992
Granulocyte-macrophage colony-stimulating factor induces a staurosporine inhibitable tyrosine phosphorylation of unique neutrophil proteins.
    Blood, 1992, May-01, Volume: 79, Issue:9

    Topics: Alkaloids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine

1992
The effect of serine and thiol protease inhibitors on the chemiluminescence of human neutrophils in investigations in vitro.
    Journal of bioluminescence and chemiluminescence, 1992, Volume: 7, Issue:1

    Topics: Calcimycin; Cysteine Proteinase Inhibitors; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine; Zymosan

1992
Tyrosine-specific protein phosphorylation during activation of human neutrophils.
    Blood, 1990, Jun-15, Volume: 75, Issue:12

    Topics: Blotting, Western; Calcimycin; Cytosol; Humans; In Vitro Techniques; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tyrosine

1990
Protein tyrosine phosphorylation in rabbit peritoneal neutrophils.
    The Biochemical journal, 1990, Jul-15, Volume: 269, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoquinolines; Animals; Calcimycin; Calcium; Immunoblotting; Isoquinolines; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Rabbits; Tetradecanoylphorbol Acetate; Tyrosine

1990
Involvement of tyrosine kinases in the activation of human peripheral blood neutrophils by granulocyte-macrophage colony-stimulating factor.
    Blood, 1991, Oct-01, Volume: 78, Issue:7

    Topics: Calcium; Genes, fos; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Hydroquinones; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Receptors, Immunologic; Receptors, Leukotriene B4; RNA, Messenger; Signal Transduction; Tyrosine

1991
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
    Blood, 1990, Nov-15, Volume: 76, Issue:10

    Topics: Calcimycin; Chemotactic Factors; Humans; Hydroquinones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

1990
Tyrosine phosphorylation in human neutrophil.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Cinnamates; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; In Vitro Techniques; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Sulfides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella

1989
Bacterial chemotactic oligopeptides and the intestinal mucosal barrier.
    Gastroenterology, 1989, Volume: 97, Issue:1

    Topics: Animals; Bile; Colon; Dithiothreitol; Ileum; Intestinal Absorption; Iodine Radioisotopes; Male; Mannitol; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Inbred Strains; Succinates; Tyrosine

1989
Studies of signal transduction in the respiratory burst-associated stimulation of fMet-Leu-Phe-induced tubulin tyrosinolation and phorbol 12-myristate 13-acetate-induced posttranslational incorporation of tyrosine into multiple proteins in activated neutr
    The Journal of biological chemistry, 1989, Jan-15, Volume: 264, Issue:2

    Topics: Cell Line; Diglycerides; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tubulin; Tyrosine

1989
Chemotactic factor induced tyrosine phosphorylation of membrane associated proteins in rabbit peritoneal neutrophils.
    Biochemical and biophysical research communications, 1988, Mar-15, Volume: 151, Issue:2

    Topics: Animals; Kinetics; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella

1988
Stimulation of tubulin tyrosinolation in rabbit leukocytes evoked by the chemoattractant formyl-methionyl-leucyl-phenylalanine.
    The Journal of cell biology, 1981, Volume: 91, Issue:1

    Topics: Alkaloids; Animals; Chemotaxis, Leukocyte; Colchicine; Leukocytes; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Paclitaxel; Peptide Synthases; Protein Binding; Rabbits; Tubulin; Tyrosine

1981
Studies in normal and chronic granulomatous disease neutrophils indicate a correlation of tubulin tyrosinolation with the cellular redox state.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:5

    Topics: Anaerobiosis; Antioxidants; Calcimycin; Diamide; Granulomatous Disease, Chronic; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxidation-Reduction; Sulfhydryl Reagents; Tubulin; Tyrosine

1983
Tubulin tyrosinolation in human polymorphonuclear leukocytes: studies in normal subjects and in patients with the Chediak-Higashi syndrome.
    The Journal of cell biology, 1982, Volume: 95, Issue:2 Pt 1

    Topics: Ascorbic Acid; Chediak-Higashi Syndrome; Humans; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxidation-Reduction; Peptide Hydrolases; Protein Processing, Post-Translational; Tubulin; Tyrosine

1982
Cross-linking of CD18 primes human neutrophils for activation of the respiratory burst in response to specific stimuli: implications for adhesion-dependent physiological responses in neutrophils.
    Journal of leukocyte biology, 1995, Volume: 58, Issue:6

    Topics: CD18 Antigens; Cell Adhesion; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoflavones; Leukocyte Common Antigens; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Respiratory Burst; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine

1995
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
    Molecular pharmacology, 1994, Volume: 45, Issue:4

    Topics: Calcium; Cell Membrane; Enzyme Activation; Glucuronidase; Glycerophospholipids; GTP-Binding Proteins; Guanosine Triphosphate; Histamine; Histamine Agonists; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositols; Phosphotyrosine; Receptors, Histamine H1; Respiratory Burst; Superoxides; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella

1994
Tyrosine phosphorylation in activated human neutrophils. Comparison of the effects of different classes of agonists and identification of the signaling pathways involved.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Jul-01, Volume: 153, Issue:1

    Topics: Calcium; Electrophoresis, Gel, Two-Dimensional; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Signal Transduction; Tyrosine; Uric Acid; Virulence Factors, Bordetella

1994
Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils.
    The Journal of cell biology, 1994, Volume: 126, Issue:4

    Topics: Amino Acid Sequence; Antibodies; CD18 Antigens; Cell Adhesion; Enzyme Activation; Epitopes; Humans; Integrins; Kinetics; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; src-Family Kinases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine

1994
Complement receptor 3 (CR3, Mac-1, integrin alpha M beta 2, CD11b/CD18) is required for tyrosine phosphorylation of paxillin in adherent and nonadherent neutrophils.
    The Journal of cell biology, 1994, Volume: 127, Issue:4

    Topics: Adolescent; Adult; CD18 Antigens; Cell Adhesion; Cell Line; Cytoskeletal Proteins; Extracellular Matrix Proteins; Female; Humans; In Vitro Techniques; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paxillin; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Complement; Signal Transduction; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine

1994
Alterations in expression of p56lck during myeloid differentiation of LSTRA cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:11

    Topics: Antigens, Differentiation; Bucladesine; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell Differentiation; Cholecalciferol; Enzyme Induction; Granulocytes; Hematopoietic Stem Cells; Histocompatibility Antigens Class II; Humans; Leukemia; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

1994
Eosinophil adhesion to vascular cell adhesion molecule-1 activates superoxide anion generation.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Aug-15, Volume: 155, Issue:4

    Topics: Adult; Cell Adhesion; Cell Adhesion Molecules; Eosinophil-Derived Neurotoxin; Eosinophils; Humans; Leukotriene C4; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neurotoxins; Phosphorylation; Ribonucleases; Superoxides; Tyrosine; Vascular Cell Adhesion Molecule-1

1995
Cross-linking of CD45 enhances activation of the respiratory burst in response to specific stimuli in human phagocytes.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Aug-15, Volume: 155, Issue:4

    Topics: CD11 Antigens; CD18 Antigens; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukocyte Common Antigens; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytes; Phosphorylation; Respiratory Burst; Tumor Necrosis Factor-alpha; Tyrosine

1995
Stimulation of human neutrophils with formyl-methionyl-leucyl-phenylalanine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases.
    Journal of immunology (Baltimore, Md. : 1950), 1993, Feb-15, Volume: 150, Issue:4

    Topics: Amino Acid Sequence; Blotting, Western; Cell Compartmentation; Enzyme Activation; ErbB Receptors; Genistein; Humans; Isoflavones; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Respiratory Burst; Tyrosine

1993
Reversible priming and protein-tyrosyl phosphorylation in human peripheral neutrophils under hypotonic conditions.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:2

    Topics: Amino Acid Sequence; Genistein; Humans; Isoflavones; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmotic Pressure; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Superoxides; Tyrosine

1993
Effect of indomethacin and aspirin on the TNF-alpha-induced priming and protein tyrosyl phosphorylation of human neutrophils.
    Physiological chemistry and physics and medical NMR, 1993, Volume: 25, Issue:1

    Topics: Animals; Aspirin; Azides; Electrophoresis, Polyacrylamide Gel; Granulocyte Colony-Stimulating Factor; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sodium Azide; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine

1993
Regulation of stimulated integrin surface expression in human neutrophils by tyrosine phosphorylation.
    Blood, 1994, Jul-15, Volume: 84, Issue:2

    Topics: Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Fluorenes; Glycine; Humans; Hydroquinones; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Tyrosine

1994
Tyrosine phosphorylation and activation of NADPH oxidase in human neutrophils: a possible role for MAP kinases and for a 75 kDa protein.
    The Biochemical journal, 1994, Nov-15, Volume: 304 ( Pt 1)

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Concanavalin A; Enzyme Activation; Genistein; Humans; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Tyrosine

1994
C5a as a model for chemotactic factor-stimulated tyrosine phosphorylation in the human neutrophil.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Mar-01, Volume: 152, Issue:5

    Topics: Benzoquinones; Cell Line; Chemotactic Factors; Complement C5a; Humans; In Vitro Techniques; Interleukin-8; Lactams, Macrocyclic; Leukotriene B4; Models, Biological; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Quinones; Receptor, Anaphylatoxin C5a; Receptors, Complement; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine

1994
Modulation of Fc gamma and complement receptor function by the glycosyl-phosphatidylinositol-anchored form of Fc gamma RIII.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Jun-15, Volume: 152, Issue:12

    Topics: Antibodies, Monoclonal; Glycosylphosphatidylinositols; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phosphorylation; Receptors, Complement; Receptors, IgG; Tyrosine

1994
Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils: no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways.
    Biochimica et biophysica acta, 1993, Nov-07, Volume: 1179, Issue:2

    Topics: Concanavalin A; Genistein; Humans; Hydroquinones; Ionomycin; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella

1993
Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase. Role of reactive oxygen intermediates.
    The Journal of biological chemistry, 1993, Aug-15, Volume: 268, Issue:23

    Topics: Animals; Cells, Cultured; GTP-Binding Proteins; Humans; Hydrogen Peroxide; Macrophages, Alveolar; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine

1993
Cytosolic [Ca2+] homeostasis and tyrosine phosphorylation of phospholipase C gamma 2 in HL60 granulocytes.
    The Journal of biological chemistry, 1993, Feb-15, Volume: 268, Issue:5

    Topics: Amino Acid Sequence; Biological Transport; Calcium; Calcium-Transporting ATPases; Cytosol; Homeostasis; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Manganese; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Terpenes; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates

1993
Rapid and reversible tubulin tyrosination in human neutrophils stimulated by the chemotactic peptide, fMet-Leu-Phe.
    Journal of cellular physiology, 1993, Volume: 154, Issue:3

    Topics: Amino Acid Sequence; Cytoplasmic Granules; Humans; Immunoblotting; Microscopy, Electron; Microscopy, Fluorescence; Microscopy, Immunoelectron; Microtubules; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tubulin; Tyrosine

1993
Beta2 integrins mediate protein tyrosine phosphorylation in human neutrophils.
    Journal of leukocyte biology, 1996, Volume: 59, Issue:5

    Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Humans; Mice; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Proteins; Tyrosine

1996
Activation of the mitogen-activated protein kinase pathway by fMet-leu-Phe in the absence of Lyn and tyrosine phosphorylation of SHC in transfected cells.
    The Journal of biological chemistry, 1996, May-31, Volume: 271, Issue:22

    Topics: Adult; Animals; Cell Line; Enzyme Activation; GTP-Binding Proteins; Humans; Mice; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Phosphorylation; Protein Kinases; Proteins; Rabbits; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; src-Family Kinases; Transfection; Tyrosine; Virulence Factors, Bordetella

1996
Tyrosine phosphorylation in inflammatory neutrophils.
    Biochemical Society transactions, 1996, Volume: 24, Issue:1

    Topics: Arthritis, Rheumatoid; Blotting, Western; Enzyme Inhibitors; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidoreductases; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Reference Values; Substance P; Synovial Fluid; Tyrosine; Vanadates

1996
Paradoxical effects of colchicine on the activation of human neutrophilis by chemotactic factors and inflammatory microcrystal.
    Journal of leukocyte biology, 1996, Volume: 59, Issue:6

    Topics: Adult; Calcium Pyrophosphate; Colchicine; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophil Activation; Neutrophils; Paclitaxel; Phosphorylation; Tyrosine; Uric Acid

1996
Tyrosine phosphorylation and subcellular redistribution of p125 ras guanosine triphosphatase-activating protein in human neutrophils stimulated with FMLP.
    FEBS letters, 1996, Apr-01, Volume: 383, Issue:3

    Topics: Cell Membrane; Concanavalin A; Cytosol; GTPase-Activating Proteins; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Phosphotyrosine; Proteins; ras GTPase-Activating Proteins; Respiratory Burst; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tyrosine

1996
Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: Androstadienes; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Humans; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tyrosine; Wortmannin

1997
Effect of protein kinase inhibitors on the superoxide generation and tyrosyl phosphorylation of prolylproline-primed human neutrophils.
    Clinical biochemistry, 1997, Volume: 30, Issue:1

    Topics: Dipeptides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Proline; Protein-Tyrosine Kinases; Respiratory Burst; Superoxides; Tyrosine

1997
Regulation of polymorphonuclear cell activation by thrombopoietin.
    The Journal of clinical investigation, 1997, Apr-01, Volume: 99, Issue:7

    Topics: Animals; Base Sequence; DNA-Binding Proteins; Humans; Interleukin-8; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Phosphorylation; Rabbits; STAT1 Transcription Factor; Superoxides; Thrombopoietin; Trans-Activators; Tyrosine

1997
Inhibition of N-formylmethionyl-leucyl-phenylalanine-stimulated tyrosine phosphorylation and phospholipase D activation by quercetin in rabbit neutrophils.
    Biochemical pharmacology, 1997, May-15, Volume: 53, Issue:10

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylation; Quercetin; Rabbits; Tyrosine

1997
Priming effect of N-acetyl-S-(3-oxo-3-carboxy-n-propyl)cysteine in human neutrophils and tyrosyl phosphorylation of 45 kDa protein.
    Clinica chimica acta; international journal of clinical chemistry, 1997, Oct-31, Volume: 266, Issue:2

    Topics: Amino Acids; Blood Proteins; Carboxylic Acids; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Superoxides; Tyrosine

1997
Syk activation is required for spreading and H2O2 release in adherent human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1998, May-15, Volume: 160, Issue:10

    Topics: Cell Adhesion Molecules; Cytoskeletal Proteins; Enzyme Activation; Enzyme Precursors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Stilbenes; Syk Kinase; Tyrosine

1998
Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells.
    Journal of leukocyte biology, 1998, Volume: 63, Issue:6

    Topics: Acetylcysteine; Androstadienes; Cell Differentiation; Chelating Agents; Cysteine; Dithiothreitol; Enzyme Activation; Free Radical Scavengers; HL-60 Cells; Humans; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Sulfhydryl Reagents; Tyrosine; Unithiol; Wortmannin

1998
Lanthionine ketimine and S-(2-aminoethyl)-L-cysteine ketimine induce the tyrosyl phosphorylation of 45 kDa protein in parallel with its stimulation of superoxide generation in human neutrophils.
    Physiological chemistry and physics and medical NMR, 1997, Volume: 29, Issue:2

    Topics: Amino Acids, Sulfur; Blood Proteins; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH Dehydrogenase; Neutrophils; Phosphorylation; Stimulation, Chemical; Superoxides; Tyrosine

1997
Monosodium urate-crystal-stimulated phospholipase D in human neutrophils.
    The Biochemical journal, 1999, Jan-15, Volume: 337 ( Pt 2)

    Topics: ADP-Ribosylation Factors; Adult; Biological Transport; Cell Compartmentation; Cytochalasin B; Cytosol; Enzyme Activation; Gout; GTP-Binding Proteins; Humans; Isoenzymes; Membranes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein-Tyrosine Kinases; Receptors, IgG; rhoA GTP-Binding Protein; Tyrosine; Uric Acid

1999
Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response.
    Journal of leukocyte biology, 1999, Volume: 65, Issue:1

    Topics: Antioxidants; Blood Proteins; Calcium; Cells, Cultured; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Oxidants; Pyrimidines; Pyrrolidines; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

1999
Phosphorylation of cytosolic phospholipase A2 and the release of arachidonic acid in human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-15, Volume: 162, Issue:4

    Topics: Acyltransferases; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Microsomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Pyridines; Tumor Necrosis Factor-alpha; Tyrosine

1999
Yops of Yersinia enterocolitica inhibit receptor-dependent superoxide anion production by human granulocytes.
    Infection and immunity, 1999, Volume: 67, Issue:3

    Topics: Actins; Adhesins, Bacterial; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Genes, Bacterial; Granulocytes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tyrosine; Yersinia enterocolitica

1999
D-cystathionine ketimine and L-cystathionine ketimine enhance superoxide generation by human neutrophils in a different manner.
    Archives of biochemistry and biophysics, 1999, Mar-01, Volume: 363, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; Lactams, Macrocyclic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serine; Staurosporine; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

1999
Selective inhibition of formyl-methionyl-leucyl-phenylalanine (fMLF)-dependent superoxide generation in neutrophils by pravastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
    Biochemical pharmacology, 1999, Dec-15, Volume: 58, Issue:12

    Topics: Drug Interactions; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kinetics; Leukocytes, Mononuclear; Luminescent Measurements; Luminol; Mevalonic Acid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Pravastatin; Protein-Tyrosine Kinases; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine; Zymosan

1999
Tyrosine kinase-regulated small GTPase translocation and the activation of phospholipase D in HL60 granulocytes.
    Journal of leukocyte biology, 1999, Volume: 66, Issue:6

    Topics: ADP-Ribosylation Factors; Cinnamates; Drug Synergism; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Sulfides; Tetradecanoylphorbol Acetate; Tyrosine; Vanadium Compounds

1999
Pyk2 and Syk participate in functional activation of granulocytic HL-60 cells in a different manner.
    Blood, 2000, Sep-01, Volume: 96, Issue:5

    Topics: CD18 Antigens; Cell Adhesion; Cell Differentiation; Enzyme Precursors; Fibrinogen; Focal Adhesion Kinase 2; Granulocytes; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Syk Kinase; Tyrosine

2000
Mutations of serine 236-237 and tyrosine 302 residues in the human lipoxin A4 receptor intracellular domains result in sustained signaling.
    Biochemistry, 2000, Nov-07, Volume: 39, Issue:44

    Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Enzyme Activation; HL-60 Cells; Humans; Hydroxyeicosatetraenoic Acids; Ligands; Lipoxins; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylation; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Serine; Signal Transduction; Transfection; Tyrosine

2000
Effect of nitrite on endothelial function in isolated lung.
    General pharmacology, 2000, Volume: 34, Issue:6

    Topics: Animals; Blood Pressure; Capillary Permeability; Carcinogens; Dimethyl Sulfoxide; Endothelium, Vascular; Free Radical Scavengers; Lipopolysaccharides; Lung; Male; Models, Animal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrites; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Tyrosine

2000
Effect of three flavonoids, 5,7,3',4'-tetrahydroxy-3-methoxy flavone, luteolin, and quercetin, on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophil.
    Archives of biochemistry and biophysics, 2001, Sep-01, Volume: 393, Issue:1

    Topics: Arachidonic Acid; Blood Proteins; Flavonoids; Humans; In Vitro Techniques; Luteolin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Quercetin; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

2001
Exposure to perflubron is associated with decreased Syk phosphorylation in human neutrophils.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:5

    Topics: Binding Sites; Cell Movement; Chemotaxis, Leukocyte; Cytosol; Enzyme Precursors; Fluorocarbons; Humans; Hydrocarbons, Brominated; Immunoblotting; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Liquid Ventilation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phosphorylation; Protein-Tyrosine Kinases; Second Messenger Systems; Syk Kinase; Tyrosine

2001
Effect of six flavonoid compounds from Ixeris sonchifolia on stimulus-induced superoxide generation and tyrosyl phosphorylation in human neutrophils.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 316, Issue:1-2

    Topics: Apigenin; Disaccharides; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Glucosides; Glucuronides; Humans; Luteolin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Plants, Medicinal; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

2002
Cholesterol-modulating agents selectively inhibit calcium influx induced by chemoattractants in human neutrophils.
    The Journal of biological chemistry, 2002, Apr-19, Volume: 277, Issue:16

    Topics: beta-Cyclodextrins; Calcium; Cell Membrane; Cholesterol; Cyclodextrins; Cytoplasm; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylation; Platelet Activating Factor; Protein Structure, Tertiary; Superoxides; Time Factors; Tyrosine

2002
Preservation of the pattern of tyrosine phosphorylation in human neutrophil lysates. II. A sequential lysis protocol for the analysis of tyrosine phosphorylation-dependent signalling.
    Journal of immunological methods, 2002, Mar-01, Volume: 261, Issue:1-2

    Topics: Adult; Buffers; Cell Fractionation; Coenzymes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Solubility; src-Family Kinases; Tyrosine; Uric Acid

2002
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidynositol 3-kinases.
    The Journal of biological chemistry, 2002, Jun-14, Volume: 277, Issue:24

    Topics: Adenosine Triphosphate; Androstadienes; Cell Membrane; Chemotaxis; Enzyme Inhibitors; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Transport; Protein-Tyrosine Kinases; Signal Transduction; Time Factors; Tyrosine; Virulence Factors, Bordetella; Wortmannin

2002
Effect of three triterpenoids, lupeol, betulin, and betulinic acid on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 325, Issue:1-2

    Topics: Anemone; Arachidonic Acid; Betulinic Acid; Hemolysis; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentacyclic Triterpenes; Phosphorylation; Proteins; Superoxides; Triterpenes; Tyrosine

2002
Effect of five flavonoid compounds isolated from leaves of Diospyros kaki on stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
    Clinica chimica acta; international journal of clinical chemistry, 2002, Volume: 326, Issue:1-2

    Topics: Antihypertensive Agents; Blood Proteins; Diospyros; Dose-Response Relationship, Drug; Flavonoids; Hemolysis; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Plant Leaves; Plant Preparations; Plants, Medicinal; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

2002
Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:11

    Topics: Arachidonic Acid; Blood Proteins; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

2002
Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium.
    Journal of leukocyte biology, 2003, Volume: 73, Issue:4

    Topics: Calcium; Calcium Signaling; CD11 Antigens; Cell Adhesion; Chemotaxis; Cytosol; Enzyme Activation; Humans; Intercellular Signaling Peptides and Proteins; Lactoferrin; Lysophosphatidylcholines; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Pancreatic Elastase; Peroxidase; Pertussis Toxin; Phosphorylation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Peptide; Serine; Tyrosine

2003
A role for Syk-kinase in the control of the binding cycle of the beta2 integrins (CD11/CD18) in human polymorphonuclear neutrophils.
    Journal of leukocyte biology, 2003, Volume: 74, Issue:2

    Topics: Blotting, Western; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Movement; Chemotaxis, Leukocyte; Enzyme Inhibitors; Enzyme Precursors; Humans; Intracellular Signaling Peptides and Proteins; Ligands; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Signal Transduction; Stilbenes; Syk Kinase; Tyrosine

2003
Effect of three triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation and tyrosyl phosphorylation and translocation of p47(phox) and p67(phox) to cell membrane in human neutrophil.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 336, Issue:1-2

    Topics: Arachidonic Acid; Aralia; Cell Membrane; Humans; Immunoblotting; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; Plant Roots; Protein Transport; Saponins; Superoxides; Tetradecanoylphorbol Acetate; Triterpenes; Tyrosine

2003
Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils.
    Cell calcium, 2003, Volume: 34, Issue:6

    Topics: Calcium; Cytosol; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; I-kappa B Proteins; Imidazoles; Mitogen-Activated Protein Kinases; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Transcription Factors; Tyrosine

2003
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
    British journal of pharmacology, 2004, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine

2004
Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.
    Biochemical and biophysical research communications, 2004, Apr-09, Volume: 316, Issue:3

    Topics: Androstadienes; Animals; Blotting, Western; Cell Differentiation; Cell Membrane; Chromones; Cytosol; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Glutathione Transferase; HL-60 Cells; Humans; Immunoblotting; Macrophages; Mice; Models, Biological; Monocytes; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phenotype; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Subcellular Fractions; Superoxides; Time Factors; Type C Phospholipases; Tyrosine; Wortmannin

2004
Primary granule release from human neutrophils is potentiated by soluble fibrinogen through a mechanism depending on multiple intracellular signaling pathways.
    American journal of physiology. Cell physiology, 2004, Volume: 287, Issue:5

    Topics: Blotting, Western; Calcium; Cells, Cultured; Cytoplasmic Granules; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinogen; Humans; Macrophage-1 Antigen; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phosphorylation; Signal Transduction; Tyrosine

2004
Prostaglandin E2 inhibits the phospholipase D pathway stimulated by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Involvement of EP2 receptors and phosphatidylinositol 3-kinase gamma.
    Molecular pharmacology, 2004, Volume: 66, Issue:2

    Topics: ADP-Ribosylation Factor 1; Calcium; Cell Membrane; Class Ib Phosphatidylinositol 3-Kinase; Dinoprostone; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; rho GTP-Binding Proteins; Tyrosine

2004
Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity.
    European journal of pharmacology, 2004, Nov-19, Volume: 504, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Degranulation; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Leukotriene D4; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Parasympatholytics; Peroxidase; Phosphodiesterase Inhibitors; Quinolines; Radioligand Assay; Rats; Receptors, Leukotriene; Tumor Necrosis Factor-alpha; Tyrosine

2004
CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes.
    European journal of immunology, 2005, Volume: 35, Issue:6

    Topics: Animals; Annexin A5; Antigens, CD; Antigens, Differentiation; Apoptosis; Caspase 3; Caspases; Cell Adhesion Molecules; Cell Differentiation; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Granulocytes; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Rats; Rats, Inbred BUF; Rats, Wistar; Time Factors; Tyrosine

2005
Critical role of proline-rich tyrosine kinase 2 in reversion of the adhesion-mediated suppression of reactive oxygen species generation by human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Jun-15, Volume: 174, Issue:12

    Topics: Cell Adhesion; Cell Cycle Proteins; Chemotactic Factors; Down-Regulation; Enzyme Activation; Focal Adhesion Kinase 2; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxidants; Phosphorylation; Platelet Activating Factor; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation

2005
Inhibition of phospholipase D activation by CYL-26z in formyl peptide-stimulated neutrophils involves the blockade of RhoA activation.
    Biochemical pharmacology, 2005, Sep-15, Volume: 70, Issue:6

    Topics: Acridines; Animals; Cell Degranulation; Enzyme Activation; Enzyme Inhibitors; Furans; Immunoprecipitation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylation; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Tyrosine

2005
SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; CD47 Antigen; Cell Membrane; Cell Movement; Chlorocebus aethiops; COS Cells; Cysteine; Cytoplasm; Dimerization; Disulfides; Epithelial Cells; HL-60 Cells; Humans; Immunoblotting; Immunoprecipitation; Inflammation; Leukocytes; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, Cell Surface; Receptors, Fc; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Subcellular Fractions; Time Factors; Tyrosine

2005
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
    Archives of biochemistry and biophysics, 2006, Feb-01, Volume: 446, Issue:1

    Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine

2006
GEA3162, a nitric oxide-releasing agent, activates non-store-operated Ca2+ entry and inhibits store-operated Ca2+ entry pathways in neutrophils through thiol oxidation.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Male; Membrane Potentials; Mercaptoethanol; Mitochondrial Membranes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Donors; Oxidation-Reduction; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfhydryl Compounds; Time Factors; Triazoles; Tyrosine; Unithiol

2006
Characterization of an activation factor released from human neutrophils after stimulation by triclinic monosodium urate crystals.
    The Journal of rheumatology, 2006, Volume: 33, Issue:5

    Topics: Calcium; Chemotaxis, Leukocyte; Crystallization; Humans; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pertussis Toxin; Phosphorylation; Platelet Activating Factor; Receptors, Formyl Peptide; Tyrosine; Uric Acid

2006
Effect of Agkistroden blomhoffi (mamushi) on superoxide generation in human neutrophils.
    Clinical biochemistry, 2006, Volume: 39, Issue:8

    Topics: Agkistrodon; Animals; Cytochromes c; Electrophoresis, Polyacrylamide Gel; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Transport; rac GTP-Binding Proteins; Serine; Superoxides; Threonine; Tyrosine

2006