tyrosine and morphine

tyrosine has been researched along with morphine in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199039 (59.09)18.7374
1990's7 (10.61)18.2507
2000's12 (18.18)29.6817
2010's6 (9.09)24.3611
2020's2 (3.03)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Bloom, AS; Brosius, KK; Dewey, WL; Harris, LS2
Anderson, TR; Bartolomé, J; Lau, C; Seidler, FJ; Slotkin, TA1
Kameyama, T; Nabeshima, T1
Nowycky, MC; Roth, RH; Walters, JR1
Ahtee, L; Carlsson, A1
Bruinvels, J; Moleman, P1
Flinchbaugh, C; Messing, RB; Waymire, JC1
Freye, E1
Sheldon, MI; Smith, CB; Sorscher, S1
Lewis, MJ; Margules, DL1
Cereda, R; Makovec, F; Pacini, MA; Revel, L; Setnikar, I1
Bhargava, HN; Ramarao, P1
Franklin, KB; Kelly, SJ1
Marshall, I; Smith, CB1
Armijo, JA; Delgado, G; Flórez, J1
Colhoun, E; Dubas, T; Lundy, P; Parker, JM1
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P1
el-Beih, ZM; Moussa, TA1
Agid, Y; Cheramy, A; Gauchy, C; Glowinski, J1
Mennear, JH; Rudzik, AD1
Corrado, AP; Graeff, FG; Verri, RA1
Dewey, WL; Harris, LS; Howes, JF; Nuite, JA1
Fukui, K; Shiomi, H; Takagi, H1
Clouet, DH; Gold, CJ; Johnson, JC; Ratner, M1
Rosenman, SJ; Smith, CB1
Hitzemann, RJ; Loh, HH; Way, EL1
Hansen, AB1
Bednarczyk, JH; Sheldon, MI; Smith, CB; Villarreal, JE2
Niebergall, PJ; Schnaare, RL; Sugita, ET1
Koe, BK; Weissman, A1
Kirby, GW1
Clouet, DH; Ratner, M1
Major, CT; Pleuvry, BJ; Rees, JM1
Fairbairn, JW; Paterson, A1
Sharman, DF1
Guitart, X; Harris, HW; Haycock, JW; Nestler, EJ; Ortiz, J; Terwilliger, RZ1
Ali, BH1
Hull, KM; Maher, TJ; Tolland, DE1
Kwan, TK; Malini, M; Perumal, R1
Higuchi, H; Kuo, CH; Miki, N; Nakano, K; Osugi, T1
Hasegawa, A; Nagamatsu, K; Tagawa, Y; Uchida, S1
Allen, RG; Chan, EC; Japón, M; Low, MJ; Mogil, JS; Rubinstein, M1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Arun, P; Devi, KV; Kurup, PA; Ravikumar, A1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F1
BANIC, B; MEDAKOVIC, M1
Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Okada, Y; Sasaki, Y; Shiotani, K; Tsuda, Y1
Brandsch, M; Dräger, B; Poeaknapo, C; Schmidt, J; Zenk, MH1
Dylag, T; Kosior, M; Kotlinska, J; Rafalski, P; Silberring, J; Talarek, S1
Bianchi, E; Cadet, P; Esch, T; Goumon, Y; Mantione, KJ; Shen, L; Sonetti, D; Stefano, GB; Zhu, W1
Kream, RM; Stefano, GB2
Pasternak, GW1
Bianchi, E; Ghelardini, C; Guarna, M; Neri, C; Palmiter, RD; Sotak, B; Stefano, G1
Law, PY; Loh, HH; Qiu, Y; Zhang, L; Zhao, H1
Agalou, A; Georganta, EM; Georgoussi, Z1
Cram, D; Desgagné-Penix, I; Facchini, PJ; Khan, MF; Nowak, J; Schriemer, DC1
Kream, RM; Ptáček, R; Stefano, GB1
Cherniakova, IV; Gudasheva, TA; Klodt, PM; Kolik, LG; Konstantinopol'skiĭ, MA; Kudrin, VS1
Kibaly, C; Law, PY; Liu, JG; Loh, HH; McGarrah, PW; Song, KY; Wang, YJ; Xu, C; Zhang, L1
Bong, D; Floyd, C; Liao, S; Pino, MJ; Tan, K; Wu, C1
Brewer, KL; Clemens, S; Kew, K; Patton, R; Rodgers, HM; Yow, J; Zeczycki, TN1
Chen, XX; Du, LZ; Gu, WZ; Lu, MP1

Reviews

4 review(s) available for tyrosine and morphine

ArticleYear
[Direct quantitative thin-layer chromatography by remission and transmission measurement. A review].
    Dansk tidsskrift for farmaci, 1971, Volume: 45, Issue:8

    Topics: Adsorption; Aspirin; Caffeine; Carbon Isotopes; Chromatography, Thin Layer; Codeine; Densitometry; Glucose; Morphine; Noscapine; Papaverine; Saponins; Thebaine; Tyrosine

1971
Biosynthesis of the morphine alkaloids.
    Science (New York, N.Y.), 1967, Jan-13, Volume: 155, Issue:3759

    Topics: Morphine; Plants, Medicinal; Tyrosine

1967
De novo biosynthesis of morphine in animal cells: an evidence-based model.
    Medical science monitor : international medical journal of experimental and clinical research, 2006, Volume: 12, Issue:10

    Topics: Alkaloids; Animals; Benzylisoquinolines; Dihydroxyphenylalanine; Models, Biological; Molecular Structure; Morphine; Papaver; Stereoisomerism; Tyrosine

2006
Psychiatric implications of endogenous morphine: up-to-date review.
    Folia biologica, 2010, Volume: 56, Issue:6

    Topics: Animals; Catecholamines; Dopamine; Humans; Leukocytes; Levodopa; Morphine; Morphine Dependence; Mytilus edulis; Nitric Oxide; Opioid Peptides; Signal Transduction; Tyrosine

2010

Other Studies

62 other study(ies) available for tyrosine and morphine

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:1

    Topics: Analgesics, Opioid; Animals; Brain; Catecholamines; Male; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Reaction Time; Stimulation, Chemical; Time Factors; Tyrosine

1976
Morphine-reserpine interactions in the adrenal medulla.
    Toxicology and applied pharmacology, 1976, Volume: 36, Issue:3

    Topics: Adrenal Medulla; Animals; Catecholamines; Epinephrine; Male; Metaraminol; Morphine; Rats; Reserpine; Time Factors; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase

1976
[Relationship between biogenic amines and analgesic action of difenamizole in heat induced reflexes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:5

    Topics: 5-Hydroxytryptophan; Aminopyrine; Analgesics; Animals; Biogenic Amines; Brain Chemistry; Drug Synergism; Fenclonine; Levodopa; Male; Mice; Morphine; Pyrazoles; Rats; Reflex; Reserpine; Serotonin; Tyrosine

1976
Dopaminergic neurons: effect of acute and chronic morphine administration on single cell activity and transmitter metabolism.
    Journal of neural transmission, 1978, Volume: 42, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dihydroxyphenylalanine; Male; Morphine; Naloxone; Neurons; Rats; Synaptic Transmission; Tyrosine

1978
Dual action of methadone on 5-HT synthesis and metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine

1979
Morphine catalepsy in relation to striatal and extrastriatal dopamine.
    Progress in neuro-psychopharmacology, 1977, Volume: 1, Issue:1-2

    Topics: Animals; Catalepsy; Dopamine; Humans; Male; Morphine; Naloxone; Rats; Receptors, Dopamine; Tyrosine

1977
Changes in brain tryptophan and tyrosine following acute and chronic morphine administration.
    Neuropharmacology, 1978, Volume: 17, Issue:6

    Topics: Animals; Brain Chemistry; Male; Morphine; Naloxone; Rats; Time Factors; Tryptophan; Tyrosine

1978
9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:2

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Dopamine; Dronabinol; Drug Implants; Drug Interactions; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Norepinephrine; Reaction Time; Tyrosine

1977
Tyrosine hydroxylation in the rat striatum after fentanyl and droperidol in vivo.
    Experimental brain research, 1976, Dec-22, Volume: 26, Issue:5

    Topics: Animals; Benserazide; Corpus Striatum; Dihydroxyphenylalanine; Droperidol; Fentanyl; Hydroxylation; Male; Morphine; Rats; Tyrosine

1976
A comparison of the effects of morphine and forced running upon the incorporation of 14-C-tyrosine into 14-C-catecholamines in mouse brain, heart and spleen.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:2

    Topics: Animals; Brain; Carbon Radioisotopes; Catecholamines; Female; Heart; Kinetics; Mice; Morphine; Myocardium; Physical Exertion; Spleen; Time Factors; Tyrosine

1975
Opioid-reinforced operant behavior: selective suppression by alpha-methyl-para-tyrosine.
    Journal of comparative and physiological psychology, 1975, Volume: 88, Issue:2

    Topics: Administration, Oral; Animals; Benzimidazoles; Benzyl Compounds; Catecholamines; Conditioning, Operant; Depression, Chemical; Diethylamines; Dose-Response Relationship, Drug; Extinction, Psychological; Humans; Injections, Intraperitoneal; Isomerism; Male; Methyltyrosines; Milk; Morphine; Morphine Dependence; Motor Activity; Rats; Recurrence; Reinforcement Schedule; Reinforcement, Psychology; Substance Withdrawal Syndrome; Tyrosine; Water Deprivation

1975
Antispasmodic activity of tiropramide.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:9

    Topics: Animals; Diarrhea; Dogs; Female; Gastric Emptying; Gastrointestinal Motility; Guinea Pigs; Hemodynamics; Humans; Intestinal Mucosa; Male; Mice; Morphine; Parasympatholytics; Rabbits; Rats; Rats, Inbred Strains; Respiration; Sincalide; Sphincter of Oddi; Tyrosine; Urinary Bladder

1989
Evidence for the involvement of central opioidergic systems in L-tyrosine methyl ester-induced analgesia in the rat.
    Pharmacology, 1988, Volume: 37, Issue:1

    Topics: Analgesia; Animals; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Tyrosine

1988
An increase in tryptophan in brain may be a general mechanism for the effect of stress on sensitivity to pain.
    Neuropharmacology, 1985, Volume: 24, Issue:11

    Topics: Animals; Brain Chemistry; Male; Morphine; Pain; Rats; Restraint, Physical; Stress, Psychological; Time Factors; Tryptophan; Tyrosine

1985
Acute and chronic morphine treatment and the hydroxylation of (1-14C)-L-tyrosine in the mouse brain.
    British journal of pharmacology, 1974, Volume: 50, Issue:3

    Topics: Animals; Brain; Brain Stem; Carbon Radioisotopes; Caudate Nucleus; Diencephalon; Dopamine; Hydroxylation; Mice; Morphine; Norepinephrine; Parietal Lobe; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase

1974
Adrenergic and serotonergic mechanisms in morphine-induced respiratory depression.
    Psychopharmacologia, 1972, Volume: 24, Issue:2

    Topics: Animals; Brain; Cats; Decerebrate State; Drug Synergism; Fenclonine; Morphine; Norepinephrine; Pargyline; Reserpine; Respiration; Respiratory Function Tests; Serotonin; Tranylcypromine; Tyrosine

1972
Investigation of mechanisms involved in toxic effects of narcotic analgesics.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1972, Volume: 5, Issue:4

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Catecholamines; Dextropropoxyphene; Drug Interactions; Female; Fenclonine; Heroin; Imipramine; Lethal Dose 50; Morphine; Naloxone; Narcotics; Norepinephrine; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine

1972
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine

1971
Effects of morphine on the Golgi apparatus and mitochondria of mammalian neurones.
    La Cellule, 1972, Volume: 69, Issue:2

    Topics: Animals; Cell Nucleus; Ganglia, Spinal; Glutathione; Golgi Apparatus; Guinea Pigs; Histocytochemistry; Inclusion Bodies; Injections, Intraperitoneal; Lipids; Mitochondria; Morphine; Neurons; Phospholipids; Riboflavin; Tryptophan; Tyrosine

1972
Acute effects of morphine on dopamine synthesis and release and tyrosine metabolism in the rat striatum.
    European journal of pharmacology, 1973, Volume: 22, Issue:3

    Topics: Animals; Basal Ganglia; Circadian Rhythm; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; In Vitro Techniques; Male; Morphine; Perchlorates; Rats; Time Factors; Tritium; Tyrosine

1973
Antagonism of analgesics by amine-depleting agents.
    The Journal of pharmacy and pharmacology, 1965, Volume: 17, Issue:5

    Topics: Animals; Aspirin; Biological Assay; Catecholamines; Methyldopa; Mice; Morphine; Reserpine; Tyrosine

1965
Antagonism of morphine analgesia by reserpine and alpha-methyltyrosine and the role played by catecholamines in morphine analgesic action.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:4

    Topics: Analgesics; Animals; Brain; Catecholamines; Dental Pulp; Drug Antagonism; Electric Stimulation; Electrophysiology; Enzymes; Hot Temperature; Methyltyrosines; Mice; Morphine; Pain; Rabbits; Reserpine; Tyrosine

1967
The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Analgesia; Animals; Ephedrine; Methyltyrosines; Mice; Morphine; Narcotic Antagonists; Neurotransmitter Agents; Pargyline; Physostigmine; Piperazines; Propranolol; Reserpine; Tail; Tetrabenazine; Tranylcypromine; Tremorine; Tyramine; Tyrosine

1970
Effect of morphine on tyrosine hydroxylase activity in mouse brain.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; In Vitro Techniques; Mice; Mixed Function Oxygenases; Morphine; Stereotaxic Techniques; Tyrosine; Tyrosine 3-Monooxygenase

1972
Morphine effects on the levels and turnover of catecholamines in rat brain.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Catecholamines; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hypothalamus; Kinetics; Male; Medulla Oblongata; Mesencephalon; Morphine; Norepinephrine; Rats; Tyrosine

1974
14 C-catecholamine synthesis in mouse brain during morphine withdrawal.
    Nature, 1972, Nov-17, Volume: 240, Issue:5377

    Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Dopamine; Drug Tolerance; Female; Humans; Injections, Intraperitoneal; Kinetics; Mice; Morphine; Morphine Dependence; Norepinephrine; Substance Withdrawal Syndrome; Time Factors; Tyrosine

1972
Effect of acute morphine administration on the metabolism of brain catecholamines.
    Life sciences. Pt. 1: Physiology and pharmacology, 1973, Jan-03, Volume: 12, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Male; Mice; Morphine; Naloxone; Tyrosine

1973
Morphine-induced increases in the incorporation of 14 C-Tyrosine into 14 C-Dopamine and 14 C-norepinephrine in the mouse brain: antagonism by naloxone and tolerance.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:3

    Topics: Adrenal Glands; Amphetamine; Animals; Brain; Carbon Isotopes; Dopamine; Drug Tolerance; Female; Levorphanol; Mice; Mice, Inbred Strains; Morphinans; Morphine; Myocardium; Naloxone; Narcotic Antagonists; Norepinephrine; Spleen; Stimulation, Chemical; Time Factors; Tyrosine

1972
Spectral determination of microdissociation constants.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:2

    Topics: Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Kinetics; Morphine; Solubility; Spectrophotometry; Tyrosine

1972
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea

1967
Catecholamine biosynthesis in brains of rats treated with morphine.
    Science (New York, N.Y.), 1970, May-15, Volume: 168, Issue:3933

    Topics: Animals; Basal Ganglia; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Drug Tolerance; Hypothalamus; Morphine; Norepinephrine; Rats; Tritium; Tyrosine

1970
Tolerance to morphine-induced increases in [14C]catecholamine synthesis in mouse brain.
    Science (New York, N.Y.), 1970, Dec-04, Volume: 170, Issue:3962

    Topics: Animals; Brain Chemistry; Carbon Isotopes; Catecholamines; Drug Tolerance; Injections, Intraperitoneal; Mice; Morphine; Narcotic Antagonists; Tyrosine

1970
A comparison of the analgesia produced by morphine and the sympathomimetic drugs.
    British journal of pharmacology, 1970, Volume: 40, Issue:1

    Topics: Amphetamine; Analgesia; Animals; Iproniazid; Mice; Morphine; Phenylalanine; Reaction Time; Reserpine; Serotonin; Sympathomimetics; Tyrosine

1970
Alkaloids as possible intermediaries in plant metabolism.
    Nature, 1966, Jun-11, Volume: 210, Issue:5041

    Topics: Carbon Isotopes; Chromatography, Paper; Indicators and Reagents; Methanol; Morphine; Papaver; Plants, Medicinal; Seeds; Tyrosine

1966
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
    British journal of pharmacology and chemotherapy, 1966, Volume: 28, Issue:2

    Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine

1966
Extracellular signal-regulated protein kinases (ERKs) and ERK kinase (MEK) in brain: regional distribution and regulation by chronic morphine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:2

    Topics: Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Immunohistochemistry; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morphine; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Time Factors; Tissue Distribution; Tyrosine

1995
The effect of L-tyrosine on some anti-nociceptive and non-nociceptive actions of morphine in mice.
    General pharmacology, 1995, Volume: 26, Issue:2

    Topics: Analgesia; Animals; Blood Glucose; Body Temperature; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Gastrointestinal Transit; Male; Mice; Morphine; Nociceptors; Rectum; Triglycerides; Tyrosine

1995
L-tyrosine potentiation of opioid-induced analgesia utilizing the hot-plate test.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3

    Topics: alpha-Methyltyrosine; Analgesia; Animals; Catecholamines; Codeine; Dose-Response Relationship, Drug; Drug Synergism; Male; Methyltyrosines; Mice; Morphine; Naloxone; Tyrosine; Valine

1994
The effect of morphine on the biosynthesis of catecholamines in the rat brain.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:2

    Topics: Aluminum Oxide; Animals; Brain; Catecholamines; Chromatography, High Pressure Liquid; Electrochemistry; Morphine; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium; Tyrosine

1994
Tyrosine phosphorylation of a 58 kDa protein induced by morphine in SK-N-SH cells.
    Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2

    Topics: Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Humans; Kinetics; Molecular Weight; Morphine; Naloxone; Nerve Tissue Proteins; Pertussis Toxin; Phosphorylation; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Tyrosine; Virulence Factors, Bordetella

1994
Mouse brain opioid receptor identification by direct ultraviolet photoaffinity labeling.
    Biochemical pharmacology, 1993, Oct-05, Volume: 46, Issue:7

    Topics: Affinity Labels; Animals; Binding Sites; Dithiothreitol; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Tritium; Tyrosine; Ultraviolet Rays

1993
Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-30, Volume: 93, Issue:9

    Topics: Amino Acid Sequence; Analgesia; Analgesics, Opioid; Animals; Base Sequence; beta-Endorphin; Circadian Rhythm; Codon; DNA Primers; Female; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Morphine; Mutagenesis, Site-Directed; Naloxone; Pain; Pituitary-Adrenal System; Polymerase Chain Reaction; Pro-Opiomelanocortin; Protein Biosynthesis; Sex Characteristics; Stem Cells; Stress, Psychological; Tyrosine

1996
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Endogenous strychnine, nicotine, and morphine--description of hypo and hyper-strychninergic, nicotinergic and morphinergic state in relation to neuropsychiatric diseases.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:6

    Topics: Adult; Alkaloids; Brain Neoplasms; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Glioma; Humans; Male; Mental Disorders; Middle Aged; Morphine; Neoplasm Proteins; Nervous System Diseases; Nicotine; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine

2000
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine

1963
THE ACTION OF RESERPINE AND ALPHA-METHYL-M-TYROSINE ON THE ANALGESIC EFFECT OF MORPHINE IN RATS AND MICE.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Analgesia; Analgesics; Animals; Iproniazid; Methyltyrosines; Mice; Morphine; Pain; Pain Management; Pharmacology; Rats; Reserpine; Tyrosine

1964
Novel 2',6'-dimethyl-L-tyrosine-containing pyrazinone opioid mimetic mu-agonists with potent antinociceptive activity in mice.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Guinea Pigs; Male; Mice; Molecular Mimicry; Morphine; Pain; Pyrazines; Receptors, Opioid, mu; Tyrosine

2004
Endogenous formation of morphine in human cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Sep-28, Volume: 101, Issue:39

    Topics: Alkaloids; Animals; Benzylisoquinolines; Cell Line; Humans; Mass Spectrometry; Morphine; Oxygen Isotopes; Rats; Stereoisomerism; Tetrahydropapaveroline; Thebaine; Tyrosine

2004
Influence of nociceptin(1-17) fragments and its tyrosine-substituted derivative on morphine-withdrawal signs in rats.
    Neuropeptides, 2004, Volume: 38, Issue:5

    Topics: Animals; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Peptide Fragments; Rats; Rats, Wistar; Receptors, Opioid; Substance Withdrawal Syndrome; Tyrosine; Vasodilator Agents

2004
Tyrosine and tyramine increase endogenous ganglionic morphine and dopamine levels in vitro and in vivo: cyp2d6 and tyrosine hydroxylase modulation demonstrates a dopamine coupling.
    Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:11

    Topics: alpha-Methyltyrosine; Animals; Base Sequence; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; DNA, Complementary; Dopamine; Enzyme Inhibitors; Ganglia, Invertebrate; Molecular Sequence Data; Morphine; Mytilus edulis; Quinidine; RNA, Messenger; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase; Up-Regulation

2005
Morphine synthesis in animals.
    Medical science monitor : international medical journal of experimental and clinical research, 2006, Volume: 12, Issue:10

    Topics: Alkaloids; Animals; Benzylisoquinolines; Dihydroxyphenylalanine; Morphine; Papaver; Stereoisomerism; Tyrosine

2006
When it comes to opiates, just say NO.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Analgesics, Opioid; Animals; Drug Tolerance; Mice; Morphine; Nitric Oxide; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tyrosine

2007
Dopamine is necessary to endogenous morphine formation in mammalian brain in vivo.
    Journal of neurochemistry, 2008, Volume: 106, Issue:6

    Topics: Animals; Body Temperature Regulation; Brain; Dopamine; Mice; Mice, Knockout; Morphine; Opioid Peptides; Sensory Thresholds; Thermosensing; Tyrosine; Tyrosine 3-Monooxygenase

2008
Src phosphorylation of micro-receptor is responsible for the receptor switching from an inhibitory to a stimulatory signal.
    The Journal of biological chemistry, 2009, Jan-23, Volume: 284, Issue:4

    Topics: Adenylyl Cyclases; Arrestins; beta-Arrestins; Cell Line; Enzyme Activation; GTP-Binding Protein alpha Subunit, Gi2; Humans; Kinetics; Morphine; Mutation; Phosphorylation; Protein Kinase Inhibitors; Receptors, Opioid, mu; Signal Transduction; src-Family Kinases; Tyrosine

2009
Multi-component signaling complexes of the delta-opioid receptor with STAT5B and G proteins.
    Neuropharmacology, 2010, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Analgesics, Opioid; Cell Line, Transformed; Conserved Sequence; Enkephalin, Leucine; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Immunoprecipitation; Morphine; Mutation; Pertussis Toxin; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyrazoles; Pyrimidines; Receptors, Opioid, delta; Signal Transduction; STAT5 Transcription Factor; Transfection; Tyrosine

2010
Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures.
    BMC plant biology, 2010, Nov-18, Volume: 10

    Topics: Alkaloids; Benzophenanthridines; Benzylisoquinolines; Biological Factors; Biosynthetic Pathways; Botrytis; Cells, Cultured; Chromatography, High Pressure Liquid; Cluster Analysis; Electrophoresis, Polyacrylamide Gel; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Isoquinolines; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Morphine; Opium; Papaver; Plant Proteins; Proteome; Proteomics; Tyrosine

2010
[Neurotensin NT (8- 13) dipeptide analog dilept increases the pain threshold and decreases the severity of morphine withdrawal syndrome in rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:10

    Topics: Animals; Dopamine; Frontal Lobe; Hypothalamus; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurotensin; Pain; Pain Threshold; Peptide Fragments; Proline; Rats; Serotonin; Severity of Illness Index; Substance Withdrawal Syndrome; Tyrosine

2013
Src-dependent phosphorylation of μ-opioid receptor at Tyr
    EMBO molecular medicine, 2017, Volume: 9, Issue:11

    Topics: Animals; Behavior, Animal; Benzodioxoles; Body Weight; HEK293 Cells; Humans; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naloxone; Narcotic Antagonists; Phosphorylation; Proto-Oncogene Proteins c-fyn; Quinazolines; Receptors, Opioid, mu; RNA Interference; RNA, Small Interfering; src-Family Kinases; Tyrosine

2017
Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation.
    Life sciences, 2021, Mar-15, Volume: 269

    Topics: Allosteric Regulation; Animals; Aspartic Acid; Cluster Analysis; Conserved Sequence; Crystallization; Humans; Ligands; Mice; Molecular Dynamics Simulation; Morphine; Principal Component Analysis; Protein Conformation; Receptors, Opioid, mu; Signal Transduction; Structural Homology, Protein; Thiophenes; Tyrosine; Urea; Water

2021
Morphine Resistance in Spinal Cord Injury-Related Neuropathic Pain in Rats is Associated With Alterations in Dopamine and Dopamine-Related Metabolomics.
    The journal of pain, 2022, Volume: 23, Issue:5

    Topics: Analgesics, Opioid; Animals; Dopamine; Female; Hyperalgesia; Metabolomics; Morphine; Neuralgia; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Tyrosine

2022
Nitric oxide inhalation inhibits inducible nitric oxide synthase but not nitrotyrosine formation and cell apoptosis in rat lungs with meconium-induced injury.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:9

    Topics: Administration, Inhalation; Animals; Apoptosis; Interleukin-1; Lung; Male; Malondialdehyde; Meconium; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Tyrosine

2005