tyrosine has been researched along with mocetinostat in 403 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (3.23) | 18.7374 |
| 1990's | 70 (17.37) | 18.2507 |
| 2000's | 205 (50.87) | 29.6817 |
| 2010's | 104 (25.81) | 24.3611 |
| 2020's | 11 (2.73) | 2.80 |
| Authors | Studies |
|---|---|
| Prota, G | 1 |
| Gallin, JI; Nath, J; Ohno, Y; Wright, DG | 1 |
| Jellinck, PH; McLachlan, JA; Newbold, RR | 1 |
| Blarzino, C; Coccia, R; De Marco, C; Foppoli, C; Rosei, MA | 1 |
| Vissers, MC; Winterbourn, CC | 1 |
| Kanno, T; Shimizu, H; Sugiyama, M; Taniguchi, K | 1 |
| Galeazzi, L; Giunta, S; Groppa, G | 1 |
| Dorris, ML; Guziec, FS; Taurog, A | 1 |
| Inaba, H; Mashiko, S; Nakano, M; Ohma, C; Suzuki, N; Takahashi, A; Totsune-Nakano, H | 1 |
| van der Walt, BJ; Van Zyl, JM | 1 |
| Burger, B; Rossouw, P; van Zyl, A; Wilson, B | 1 |
| Denison, RC; Tsan, MF; Turkall, RM | 1 |
| Blair, H; Okun, MR; Schley, L; Ziegelstein, R | 1 |
| Murakami, H; Nagata, S; Yoshikawa, A | 1 |
| Charlton, TS; Domigan, NM; Duncan, MW; Kettle, AJ; Winterbourn, CC | 1 |
| Beer, K; Goodenough, UW; Waffenschmidt, S; Woessner, JP | 1 |
| Heinecke, JW; Mueller, DM; Savenkova, ML | 1 |
| Daehnke, HL; Goldstein, JA; Heinecke, JW; Li, W | 1 |
| Francis, GA; Goldstein, JA; Heinecke, JW; Li, W | 1 |
| Inaba, H; Nakano, M; Totsune, H | 1 |
| Fujimoto, S; Kawakami, N; Ohara, A | 1 |
| Dunford, HB; Marquez, LA | 1 |
| Kettle, AJ | 2 |
| Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Cistola, DP; Hazen, SL; Heinecke, JW; Hsu, FF; Jacob, JS; Mueller, DM; Muzaffar, S | 1 |
| Buttery, LD; Carpenter, A; Cohen, J; Evans, TJ; Polak, JM; Springall, DR | 1 |
| Beckman, JS; Rosen, H; Sampson, JB | 1 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Hsu, FF; Mueller, DM | 1 |
| Bryan, N; Zuckerman, SH | 1 |
| Christensen, BM; Hodgeman, BA; Li, J | 1 |
| Nakano, M; Nishida, A; Totsune, H; Ushijima, Y | 1 |
| Peter, MG; Wollenberger, U | 1 |
| Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Pennathur, S; Rasmussen, JE | 1 |
| Kettle, AJ; Pichorner, H; Winterbourn, CC | 1 |
| Hazen, SL; Heinecke, JW | 1 |
| Brunet, S; Guertin, F; Lairon, D; Levy, E | 1 |
| Crowley, JR; d'Avignon, A; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Heinecke, JW | 5 |
| Halliwell, B | 1 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Mueller, DM | 1 |
| Cuzzocrea, S; Gilad, E; Hake, P; Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Gmeiner, BM; Held, I; Hermann, M; Kapiotis, S; Seelos, C; Sengoelge, G | 1 |
| Baudry, N; Carayon, P; Delom, F; Lejeune, PJ; Mallet, B; Vinet, L | 1 |
| Cuzzocrea, S; Salzman, AL; Szabó, C; Zingarelli, B; Zsengellér, Z | 1 |
| Anderson, MM; d'Avignon, A; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Arai, Y; Cheng, X; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, Ji; Shimokawa, H; Takeshita, A | 1 |
| Hayashi, T; Jasin, HE; Uesugi, M | 1 |
| Stanbro, WD | 1 |
| Inoue, M; Ishisaka, R; Kanno, T; Nakahara, H; Sato, EF; Utsumi, K; Yasuda, T; Yoshioka, T | 1 |
| Beckman, JS; Rosen, H; Sampson, JB; Ye, Y | 1 |
| Capeillère-Blandin, C | 1 |
| Britigan, BE; Buettner, GR; Gaut, JP; Heinecke, JW; Lin, TS; McCormick, ML | 1 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Rasmussen, JE; Turk, J | 1 |
| Salzman, AL; Szabó, C; Zingarelli, B | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E | 1 |
| Denke, A; Elstner, EF; Schneider, W | 1 |
| Denke, A; Elstner, EF; Mann, E; Schempp, H; Schneider, W | 1 |
| Franceschi, C; Galeazzi, L; Giunta, S; Ronchi, P | 1 |
| Hazen, SL; Hegele, RA; Heinecke, JW; Huff, MW; Miller, DB; Whitman, SC | 1 |
| Tien, M | 1 |
| Gmeiner, B; Held, I; Hermann, M; Hofbauer, R; Kapiotis, S; Seelos, C | 1 |
| Baldi, B; Indiani, C; Neri, F; Smulevich, G; Vind, J; Welinder, KG | 1 |
| Caputi, AP; Ciriaco, E; Costantino, G; Cuzzocrea, S; de Sarro, A; de Sarro, G; Laurà, R; Mazzon, E | 1 |
| Fukuyama, N; Hataishi, R; Hirano, S; Honda, K; Kobayashi, H; Nakazawa, H; Tomita, T | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Zingarelli, B | 1 |
| Guittet, O; Lepoivre, M; Roy, B | 1 |
| Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Mazzon, E | 1 |
| Caputi, AP; Ciliberto, G; Costantino, G; Cuzzocrea, S; De Sarro, A; De Sarro, G; Di Rosa, M; Ialenti, A; Mazzon, E; Rombolà, L; Sautebin, L; Thiemermann, C | 1 |
| Sutherland, WH; Upritchard, JE | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E; Reiter, RJ; Tan, DX | 1 |
| Fujimoto, S; Hayakawa, T; Kawakami, N; Shimohama, S | 1 |
| Cotton, RT; Salzman, A; Stern, Y; Zingarelli, B | 1 |
| Abu-Soud, HM; Chen, Y; Cohen, PA; Hazen, SL; Hoff, HF; MacPherson, JC; Mitra, SN; Mukhopadhyay, C; Podrez, EA; Schmitt, D; Shen, Z; Wu, W; Zhang, R | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E; Micali, A | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Filippelli, A; Imperatore, F; Luongo, C; Mangoni, G; Mazzon, E; Rossi, F; Scafuro, MA | 1 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Heller, JI; Pennathur, S; Salvay, DM; Wagner, P | 1 |
| Kettle, AJ; Senthilmohan, R; van Dalen, CJ; Winterbourn, CC | 1 |
| Elstner, EF; Schempp, H; Weiser, D | 1 |
| Aratani, Y; Kodama, T; Koyama, H; Nakano, K; Niki, E; Noguchi, N | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Macarthur, H; Mazzon, E; Micali, A; Misko, TP; Salvemini, D | 1 |
| Han, Q; Li, G; Li, J | 1 |
| Calabrò, G; Caputi, AP; Costantino, G; Cucinotta, G; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Akaike, T; Maeda, H; Sawa, T | 1 |
| Brown, PA; Chatterjee, PK; Cuzzocrea, S; Mota-Filipe, H; Stewart, KN; Thiemermann, C; Zacharowski, K | 2 |
| Abu-Soud, HM; Hazen, SL; Podrez, EA | 1 |
| Liaudet, L; Mabley, JG; Salzman, AL; Soriano, FG; Szabo, C; Szabó, E; Virág, L | 1 |
| Cross, CE; Eiserich, JP; Marelich, GP; Nguyen, MN; Shigenaga, MK; Van Der Vliet, A | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; De Sarro, A; Mazzon, E; Serraino, I | 1 |
| Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cucinotta, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; McDonald, MC; Siriwardena, D; Thiemermann, C | 1 |
| Irazuzta, JE; Mirkin, LD; Zingarelli, B | 1 |
| Britti, D; Caputi, AP; Ciccolo, A; Cuzzocrea, S; Lepore, V; Mazzon, E; McDonald, MC; Mota-Filipe, H; Terranova, ML; Thiemermann, C | 1 |
| Caputi, AP; Ciccolo, A; Cuzzocrea, S; Dugo, L; Fonti, MT; Lepore, V; Mazzon, E; McDonald, MC; Terranova, ML; Thiemermann, C | 1 |
| Barberi, I; Caputi, AP; Cordaro, S; Costantino, G; Cuzzocrea, S; De Sarro, A; Fulia, F; Gitto, E; Mazzon, E; Serraino, I | 1 |
| Calabro, G; Caputi, AP; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; van De LOO, FA | 1 |
| Crowley, JR; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
| Haller, H; Kettritz, R; Luft, FC; Schreiber, A | 1 |
| Aston, K; Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D | 1 |
| Caputi, AP; Ciccolo, A; Cuzzocrea, S; Lepore, V; Mazzon, E; Serraino, I; Terranova, ML | 1 |
| Alt, E; Exner, M; Gmeiner, B; Hermann, M; Hofbauer, R; Kapiotis, S; Minar, E; Quehenberger, P; Speiser, W | 1 |
| Anderson, MM; Brennan, ML; Crowley, JR; Hazen, SL; Heinecke, JW; Jacob, JS; Lim, LL; Lusis, AJ; Mehta, AC; Qu, XD; Shi, W; Shih, DM; Wang, X | 1 |
| Brivio, MF; de Eguileor, M; Grimaldi, A; Lanzavecchia, G; Valvassori, R; Vigetti, D | 1 |
| Britti, D; Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; Mazzon, E; McDonald, MC; Mota-Filipe, H; Terranova, ML; Thiemermann, C | 1 |
| Douglass, LW; Ledbetter, TK; Paape, MJ | 1 |
| Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Lai, PS; Lin, KT; Linask, KK; Liu, X; Nagele, RG; Sun, FF; Wang, C; Wong, PY; Yin, K; Yue, G | 1 |
| Augusto, O; Giorgio, S; Linares, E; Mortara, RA; Santos, CX; Yamada, AT | 1 |
| Lass, A; Mayer, B; Pfeiffer, S; Schmidt, K | 2 |
| Drabik, G; Naskalski, JW | 1 |
| Barbera, A; Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; Dugo, L; Fonti, MT; Mazzon, E | 1 |
| Britti, D; Caputi, AP; Cuzzocrea, S; De Sarro, A; Mazzon, E | 1 |
| Al-Affar, EB; Liaudet, L; Szabó, C; Yang, Z | 1 |
| Bian, K; Murad, F | 1 |
| Kettle, AJ; Winterbourn, CC | 1 |
| Belaaouaj, A; Brennan, ML; Byun, J; Gaut, JP; Heinecke, JW; Henderson, JP; Hotchkiss, RS; Lusis, AJ; Richter, GM; Tran, HD; Yeh, GC | 1 |
| Heinecke, JW; Himmelfarb, J; Loseto, G; McMenamin, ME | 1 |
| Chapman, AL; Hampton, MB; Kettle, AJ; Senthilmohan, R; Winterbourn, CC | 1 |
| Caputi, AP; Cuzzocrea, S; Dugo, L; Mazzon, E; Riley, DP; Salvemini, D | 1 |
| Baldus, S; Brennan, ML; Bullard, DC; Castro, L; Chumley, P; Eiserich, JP; Figueroa, M; Freeman, BA; Lusis, AJ; Ma, W; Mani, A; Moore, KP; Tousson, A; White, CR | 1 |
| Barrabés, JA; Blanco, J; Garcia-Dorado, D; Lidón, RM; Mirabet, M; Pizcueta, P; Puigfel, Y; Ruiz-Meana, M; Soler-Soler, J; Soriano, B | 1 |
| Murakami, H; Omura, T; Sakai, H | 1 |
| Aratani, Y; Fukuyama, N; Hirabayashi, H; Koyama, H; Maeda, N; Nakazawa, H; Shinohara, Y; Takizawa, S | 1 |
| Hazen, SL; Nauseef, WM; Shen, Z; Zhang, R | 1 |
| Abu-Soud, HM; Borchers, MT; Brennan, ML; Frost, H; Fu, X; Hazen, SL; Ischiropoulos, H; Lee, JJ; Lee, NA; Lenkiewicz, E; Lusis, AJ; Narine, L; Shen, Z; Song, W; Vadseth, C; Wu, W | 1 |
| Cantos, E; Espín, JC; Gil, MI; Tudela, JA | 1 |
| Belaaouaj, A; Byun, J; Carroll, JA; Gaut, JP; Heinecke, JW; Hotchkiss, RS; Lauber, WM; Tran, HD | 1 |
| Allmeling, AM; Dörger, M; Kiefmann, R; Krombach, F; Messmer, K; Münzing, S | 1 |
| Crowley, JR; Heinecke, JW; Rosen, H | 1 |
| Galiñanes, M; Matata, BM | 1 |
| Cuzzocrea, S; Mannaioni, PF; Marzocca, C; Masini, E; Mazzon, E; Salvemini, D | 1 |
| Allmeling, AM; Dörger, M; Kiefmann, R; Krombach, F; Schropp, A | 1 |
| Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; de Sarro, A; Dugo, L; Mazzon, E; McDonald, MC; Thiemermann, C | 1 |
| Ikeda, M; Suzuki, M; Tabuchi, M; Tomita, T | 1 |
| Hataishi, R; Hirano, S; Jones, RC; Kobayashi, H; Takahashi, Y; Zapol, WM | 1 |
| Alexander, CB; Baldus, S; Brennan, ML; Eiserich, JP; Freeman, BA; Jackson, RM | 1 |
| Barbera, A; Caputi, AP; Centorrino, T; Chatterjee, PK; Ciccolo, A; Cuzzocrea, S; Dugo, L; Fulia, F; Mazzon, E; McDonald, MC; Serraino, I; Thiemermann, C | 1 |
| Persson, K; Poljakovic, M | 1 |
| Kulmacz, RJ; Tsai, AL; van der Donk, WA | 1 |
| Anraku, S; Nakayama, R; Ushijima, K; Yano, T | 1 |
| Arnhold, J; Furtmüller, PG; Jantschko, W; Obinger, C; Pichler, H | 1 |
| Kimura, S; Kodama, N; Kubo, M; Nagase, H; Nakajima, M; Nakamura, H; Ogino, K | 1 |
| Auchère, F; Capeillère-Blandin, C | 1 |
| Buss, IH; Darlow, BA; Kettle, AJ; Mogridge, N; Senthilmohan, R; Winterbourn, CC | 1 |
| Britti, D; Brown, PA; Chatterjee, PK; Cuzzocrea, S; Dugo, L; Kvale, EO; Mota-Filipe, H; Patel, NS; Sivarajah, A; Stewart, KN; Thiemermann, C; Yaqoob, MM | 1 |
| Aiboshi, J; Ambruso, DR; Bannerjee, A; Barnett, CC; Bjornsen, AJ; Elzi, DJ; England, KM; Hamiel, C; Harbeck, RJ; Kelher, M; McLaughlin-Malaxecheberria, N; Musters, RJ; Paterson, AJ; Silliman, CC; Wyman, TH | 1 |
| Bian, K; Gao, Z; Murad, F; Weisbrodt, N | 1 |
| Aratani, Y; Fukuyama, N; Ichimori, K; Ishida-Okawara, A; Kameoka, Y; Kohi, F; Koyama, H; Nakazawa, H; Suzuki, K; Takizawa, S | 1 |
| Kato, Y; Nagao, A; Osawa, T; Terao, J | 1 |
| Fraga, C; Mulligan, MS; Naidu, BV; Salzman, AL; Szabo, C; Verrier, ED | 1 |
| Caputi, AP; Chatterjee, PK; Cuzzocrea, E; Cuzzocrea, S; Di Paola, R; Fulia, F; Genovese, T; Ianaro, A; Patel, NS; Pisano, B; Rossi, A; Sautebin, L; Thiemermann, C | 1 |
| Chen, Z; Gou, D; Jin, N; Liu, L; Narasaraju, TA; Narendranath, CR | 1 |
| Girotto, S; Magliozzo, RS; Yu, S; Zhao, X | 1 |
| Abeysinghe, RD; Ball, T; Cukier, RI; Hsi, LC; Micielli, R; Mills, DA; Rieke, CJ; Seibold, SA; Smith, WL | 1 |
| Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Di Rosa, M; Dugo, L; Genovese, T; Ianaro, A; Patel, NS; Pisano, B; Thiemermann, C | 1 |
| SIZER, IW | 1 |
| BOUCHILLOUX, S; LISSITZKY, S; MAYRARGUE-KODJA, A | 1 |
| GROSS, AJ; SIZER, IW | 1 |
| DAVIS, AM; DEGROOT, LJ | 1 |
| BJORKSTEN, F; GRASBECK, R; KARLSSON, R; LAMBERG, BA | 1 |
| YIP, CC | 1 |
| Ansari, AA; Balasubramanian, S; Bowlus, CL; Coppel, RL; Eiserich, JP; Gershwin, ME; Van De Water, J; Wu, CT | 1 |
| Caputi, AP; Cuzzocrea, S; Di Paola, R; Dugo, G; Dugo, P; Genovese, T; Mondello, L; Morabito, D; Rossi, A; Sautebin, L; Serraino, I | 1 |
| Britti, D; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Serraino, I; Siriwardena, A; Thiemerman, C; Virlos, I | 1 |
| Andrekopoulos, C; Joseph, J; Kalivendi, S; Kalyanaraman, B; Zhang, H | 1 |
| Baker, PR; Freeman, BA; Schopfer, FJ | 1 |
| Autore, G; Caputi, AP; Cuzzocrea, S; Di Paola, R; Marzocco, S; Mazzon, E; Pinto, A; Thiemermann, C | 1 |
| Castro, L; Eiserich, JP; Freeman, BA; Radi, R; Sweeney, S | 1 |
| Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Di Rosa, M; Dugo, L; Genovese, T; Ialenti, A; Ianaro, A; Maffia, P; Patel, NS; Pisano, B; Thiemermann, C | 1 |
| Augusto, O; Bonini, MG; Fernandes, DC | 1 |
| Gao, J; Zeng, B; Zhou, L | 1 |
| Caputi, AP; Cuzzocrea, S; Di Paola, R; Dugo, L; Genovese, T; Marzocco, S; Mazzon, E | 1 |
| LEROUX, H | 1 |
| Herold, S | 1 |
| Cho, EJ; Rhyu, DY; Yokozawa, T | 1 |
| Bao, F; Chen, Y; Dekaban, GA; Weaver, LC | 1 |
| Kiss, MH; Laurindo, IM; Lotito, AP; Mello, SB; Muscará, MN; Novaes, GS; Silva, CA; Teixeira, SA | 1 |
| Caputi, AP; Cuzzocrea, S; Di Paola, R; Genovese, T; Thiemermann, C; Threadgill, M | 1 |
| Autore, G; Britti, D; Cuzzocrea, S; Di Paola, R; Genovese, T; Marzocco, S; Pinto, A; Scollo, G; Sorrentino, R | 1 |
| Bani, D; Ciampa, A; Cuzzocrea, S; Masini, E; Mazzocca, C; Suzuki, H; Suzuki, Y | 1 |
| Deretic, V; Master, S; Rusnak, F; Timmins, GS | 1 |
| Bergt, C; Brunzell, J; Byun, J; Chait, A; Geary, RL; Green, PS; Heinecke, JW; Kassim, SY; McDonald, TO; O'brien, K; Oram, JF; Pennathur, S; Shao, B; Singh, P | 1 |
| Cuzzocrea, S; De Sarro, A; Di Paola, R; Genovese, T; Mazzon, E; Muià, C; Patel, NS; Thiemermann, C | 1 |
| Brennan, ML; Fox, PL; Fu, X; Goormastic, M; Hazen, SL; Ischiropoulos, H; Kinter, M; Nukuna, B; Schmitt, D; Settle, M; Smith, JD; Sun, M; Thomson, L; Zheng, L | 1 |
| Anantharamaiah, GM; Bergt, C; Brunzell, J; Byun, J; Chait, A; Fu, X; Geary, RL; Heinecke, JW; McDonald, TO; O'Brien, K; Oram, JF; Pennathur, S; Singh, P | 1 |
| Service, RF | 1 |
| Caputi, AP; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Muià, C | 1 |
| Barillas-Mury, C; Gupta, L; Han, YS; Kumar, S | 1 |
| Cinel, I; Cinel, L; Ercan, B; Kanik, A; Koksel, O; Oral, U; Ozdulger, A; Tamer, L | 1 |
| Brown, KL; Covell, JW; García, RA; Go, KV; Pavelec, RS; Villarreal, FJ | 1 |
| Akyol, O; Armutcu, F; Aydogdu, I; Gurel, A; Iraz, M; Kotuk, M; Ozen, S; Turkoz, Y; Yildirim, Z | 1 |
| Brown, PA; Chatterjee, PK; Cuzzocrea, S; Mota-Filipe, H; Sivarajah, A; Stewart, KN; Thiemermann, C; Todorovic, Z | 1 |
| Caselli, G; Ferrari, F; Makovec, F; Mennuni, L; Zanelli, T | 1 |
| Bergt, C; Fu, X; Green, P; Heinecke, JW; Oda, MN; Oram, JF; Shao, B; Voss, JC | 1 |
| Dozaki, N; Kato, Y; Kawai, Y; Kitamoto, N; Kondo, H; Morinaga, H; Osawa, T | 1 |
| Caputi, AP; Catalano, P; Crimi, N; Cuzzocrea, S; Di Paola, R; Genovese, T; Mastruzzo, C; Mazzon, E; Sortino, M; Thiemermann, C; Vancheri, C | 1 |
| Bayir, H; Billiar, TR; Borisenko, GG; Janesko, KL; Kagan, VE; Kochanek, PM; Tyurina, YY; Vagni, VA; Williams, DL | 1 |
| Büyükafşar, K; Cinel, L; Değirmenci, U; Kaplan, MB; Köksel, O; Kubat, H; Ozdülger, A; Tamer, L; Tiftik, RN; Yildirim, C | 1 |
| Aoyagi, K; Cho, EJ; Rhyu, DY; Shibahara, N; Yokozawa, T | 1 |
| Chen, M; Henderson, JD; Johnson, CP; Khanna, AK; Nilakantan, V; Pieper, GM; Roza, AM; Szabó, C; Zhou, J | 1 |
| Chung, HY; Lee, J; Son, TG; Yu, BP; Zou, Y | 1 |
| Bao, M; Clauser, K; Conley, PB; Hart, MJ; Komuves, L; Lin, H; Nanda, N; Phillips, DR; Quertermous, T | 1 |
| Ayaz, L; Aytacoglu, B; Bayri, O; Dikmengil, M; Döndaş, A; Ozeren, M; Sucu, N; Tamer, L | 1 |
| Auger, G; Coeytaux, K; Decottignies, P; Houée-Levin, C; Lemaire, G; Lepoivre, M | 1 |
| Cuzzocrea, S; De Sarro, A; Di Paola, R; Genovese, T; Mazzon, E; Muià, C | 1 |
| Batthyány, C; Cassina, A; Cerveñansky, C; Durán, R; Radi, R; Souza, JM | 1 |
| Chen, CL; Chen, YR; He, G; Liu, X; Zweier, JL | 1 |
| Aksöyek, S; Avlan, D; Camdeviren, H; Ozturhan, H; Oztürk, C; Tamer, L; Taşkinlar, H | 1 |
| Choi, DK; Heinecke, JW; Jackson-Lewis, V; Pennathur, S; Perier, C; Przedborski, S; Teismann, P; Tieu, K; Vila, M; Vonsattel, JP; Wu, DC | 1 |
| Cauvi, DM; Chabaud, O; Nlend, MC; Venot, N | 1 |
| Cuzzocrea, S; De Sarro, A; Genovese, T; Mazzon, E; Menegazzi, M; Muià, C; Paola, RD; Suzuki, H | 1 |
| Brubaker, G; Gross, E; Hazen, SL; Kinter, M; Peng, DQ; Settle, M; Smith, JD; Wu, Z; Zheng, L | 1 |
| Chen, XX; Du, LZ; Gu, WZ; Lu, MP | 1 |
| Caputi, AP; Crisafulli, C; Cuzzocrea, S; De Paola, R; Genovese, T; Mazzon, E; Menegazzi, M; Muià, C; Suzuki, H | 1 |
| Asher, LV; Atkins, JL; Ayyagari, V; Gorbunov, NV | 1 |
| Joseph, J; Kalyanaraman, B; Xu, Y; Zhang, H | 1 |
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| Chen, JW; Nilges, M; Rodríguez, E; Weissleder, R | 1 |
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| de Koning, LJ; de Koster, CG; Dekker, HL; Gruppen, H; Heijnis, WH; van Berkel, WJ; Westphal, AH; Wierenga, PA | 1 |
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| Kostevich, VA; Mikhalchik, EV; Sokolov, AV; Vasilyev, VB; Vlasova, II | 1 |
| Sato, S | 2 |
| Furtmüller, PG; Hofbauer, S; Obinger, C; Paumann-Page, M; Pfanzagl, V; Sevcnikar, B | 1 |
| Aljasir, MA; Almatroodi, SA; Almatroudi, A; Alsahli, MA; Rahmani, AH; Syed, MA | 1 |
| Bernard, K; Bone, NB; Byun, J; Johnson, MR; Kurundkar, A; Locy, ML; Pennathur, S; Rangarajan, S; Thannickal, VJ; Yang, S; Zhou, Y; Zmijewski, JW | 1 |
| Choromańska, B; Choromańska, K; Dadan, J; Maciejczyk, M; Myśliwiec, H; Myśliwiec, P; Wojskowicz, P; Zalewska, A; Łuba, M | 1 |
| Bhat, RV; Chua, J; Fritsche-Danielson, R; Gan, LM; Hausenloy, DJ; Hernandez-Resendiz, S; Jonsson, MKB; Knöll, R; Kp, MMJ; Liehn, EA; Lin, YH; Michaëlsson, E; Ramachandra, CJA; Ryden-Markinhuhta, K; Sadayappan, S; Shim, W; Tang, HC; Wong, P | 1 |
| Alexeev, EE; Cartwright, IM; Colgan, SP; Dowdell, AS; Henen, MA; Lanis, JM; Lee, JS; Onyiah, JC; Ornelas, A; Schaefer, REM; Vögeli, B | 1 |
| Jin, Z; Lu, N; Tian, R; Zhou, L | 1 |
| Ekiert, H; Kołton, A; Królicka, A; Makowski, W; Malek, K; Miernicka, K; Pięta, Ł; Szopa, A; Tokarz, B; Tokarz, KM | 1 |
| Chuang, CY; Davies, MJ; Gamon, LF; Hawkins, CL; Malle, E; Xu, S | 1 |
| Cao, W; Chen, K; Lei, J; Li, Y; Liu, X; Liu, Y; Tan, B; Xia, Q; Xia, Z; Xiao, B; Zhong, L; Zhu, C; Zhu, J | 1 |
16 review(s) available for tyrosine and mocetinostat
| Article | Year |
|---|---|
Peroxynitrite-dependent tyrosine nitration catalyzed by superoxide dismutase, myeloperoxidase, and horseradish peroxidase.
Topics: Kinetics; Nitrates; Peroxidase; Substrate Specificity; Superoxide Dismutase; Tyrosine | 1996 |
Pathways for oxidation of low density lipoprotein by myeloperoxidase: tyrosyl radical, reactive aldehydes, hypochlorous acid and molecular chlorine.
Topics: Aldehydes; Animals; Arteriosclerosis; Chlorine; Cholesterol, LDL; Free Radicals; Humans; Hypochlorous Acid; Lipoproteins, LDL; Macrophages; Oxidants; Oxidation-Reduction; Peroxidase; Tyrosine | 1997 |
Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders.
Topics: Aldehydes; Arteriosclerosis; Chlorine; Humans; Inflammation; Oxidative Stress; Peroxidase; Phagocytes; Tyrosine | 1999 |
Nitric oxide: a radical molecule in quest of free radicals in proteins.
Topics: Amino Acids; Animals; Arachidonic Acid; Bacterial Proteins; Binding Sites; Free Radicals; Humans; Iron; Mice; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Prostaglandin-Endoperoxide Synthases; Proteins; Tyrosine | 1999 |
Eosinophil-dependent bromination in the pathogenesis of asthma.
Topics: Asthma; Bromine; Eosinophils; Humans; Peroxidase; Reactive Oxygen Species; Tyrosine | 2000 |
Myeloperoxidase-generated oxidants and atherosclerosis.
Topics: Aldehydes; Amino Acids; Animals; Arteriosclerosis; Catalysis; Free Radicals; Humans; Lipoproteins, LDL; Nitro Compounds; Oxidants; Oxidation-Reduction; Peroxidase; Tyrosine | 2000 |
Tyrosyl radical production by myeloperoxidase: a phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins.
Topics: Arteriosclerosis; Cross-Linking Reagents; Free Radicals; Humans; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Phagocytes; Proteins; Tyrosine | 2002 |
The cyclooxygenase reaction mechanism.
Topics: Animals; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Free Radicals; Humans; Isoenzymes; Membrane Proteins; Molecular Conformation; Peroxidase; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Tyrosine | 2002 |
NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response?
Topics: Animals; Free Radicals; Humans; Inflammation; Models, Biological; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrosation; Peroxidase; Proteins; Signal Transduction; Tyrosine | 2003 |
The role of myeloperoxidase in HDL oxidation and atherogenesis.
Topics: Apolipoprotein A-I; Atherosclerosis; ATP-Binding Cassette Transporters; Biological Transport; Biomarkers; Chlorine; Humans; Lipoproteins, HDL; Oxidation-Reduction; Peroxidase; Tyrosine | 2007 |
Sjøgren's syndrome-associated oxidative stress and mitochondrial dysfunction: prospects for chemoprevention trials.
Topics: Biomarkers; Chemoprevention; DNA Damage; Glutathione; Humans; Mitochondria; Oxidative Stress; Peroxidase; Saliva; Sjogren's Syndrome; Tumor Necrosis Factor-alpha; Tyrosine | 2013 |
Catalase in peroxidase clothing: Interdependent cooperation of two cofactors in the catalytic versatility of KatG.
Topics: Antitubercular Agents; Archaea; Bacteria; Bacterial Proteins; Catalase; Coenzymes; Heme; Isoniazid; Methionine; Models, Molecular; Mycobacterium tuberculosis; Peroxidase; Prodrugs; Tryptophan; Tyrosine | 2014 |
Development and application of oxidative stress biomarkers.
Topics: Biomarkers; DNA; Dopamine; Functional Food; Humans; Inflammation; Lipid Peroxidation; Lipid Peroxides; Lysine; Oxidative Stress; Peroxidase; Phospholipids; Reactive Oxygen Species; Tyrosine | 2018 |
[Development and Application of Catalytic Tyrosine Modification].
Topics: Catalysis; Heme; Hemeproteins; Luminescence; Luminol; Peroxidase; Tyrosine | 2018 |
[Development and Application of Catalytic Tyrosine Chemical Modification].
Topics: Catalysis; Cysteine; Electron Transport; Electrons; Hemin; Luminol; Lysine; Oxidation-Reduction; Peroxidase; Proteins; Ruthenium; Tyrosine | 2019 |
Protein Chemical Modification Using Highly Reactive Species and Spatial Control of Catalytic Reactions.
Topics: Biocatalysis; Coordination Complexes; Hemin; Humans; Laccase; Molecular Structure; Peroxidase; Protein Processing, Post-Translational; Tyrosine | 2022 |
4 trial(s) available for tyrosine and mocetinostat
| Article | Year |
|---|---|
Inhaled nitric oxide for modulation of ischemia-reperfusion injury in lung transplantation.
Topics: Administration, Inhalation; Adult; Bronchoalveolar Lavage Fluid; Female; Free Radical Scavengers; Free Radicals; Graft Rejection; Humans; Interleukin-8; Lung; Lung Transplantation; Male; Middle Aged; Neutrophils; Nitric Oxide; Peroxidase; Reperfusion Injury; Tyrosine | 2007 |
Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase.
Topics: Aged; Animals; Antithrombins; Biological Availability; Cattle; Female; Fluorescent Antibody Technique; Hirudins; Humans; Male; Methylation; Middle Aged; Nitric Oxide; Peptide Fragments; Peroxidase; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Tyrosine; Vasodilation | 2008 |
Oxidative and nitrosative stress markers in patients on hemodialysis and peritoneal dialysis.
Topics: Adult; Biomarkers; Female; Humans; Male; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Peroxidase; Sulfhydryl Compounds; Tyrosine | 2011 |
Mediterranean diets supplemented with virgin olive oil and nuts enhance plasmatic antioxidant capabilities and decrease xanthine oxidase activity in people with metabolic syndrome: The PREDIMED study.
Topics: Aged; Aged, 80 and over; Biomarkers; Catalase; Cholesterol; Diet, Fat-Restricted; Diet, Mediterranean; Female; Follow-Up Studies; Humans; Male; Metabolic Syndrome; Middle Aged; Nutrition Assessment; Nuts; Olive Oil; Patient Compliance; Peroxidase; Superoxide Dismutase; Surveys and Questionnaires; Tyrosine; Xanthine Oxidase | 2016 |
383 other study(ies) available for tyrosine and mocetinostat
| Article | Year |
|---|---|
The role of peroxidase in melanogenesis revisited.
Topics: Benzoquinones; Dihydroxyphenylalanine; Indoles; Melanins; Molecular Structure; Monophenol Monooxygenase; Oxidation-Reduction; Peroxidase; Plant Proteins; Tyrosine | 1992 |
A novel post-translational incorporation of tyrosine into multiple proteins in activated human neutrophils. Correlation with phagocytosis and activation of the NADPH oxidase-mediated respiratory burst.
Topics: Blood Proteins; Cells, Cultured; Edetic Acid; Free Radical Scavengers; Granulomatous Disease, Chronic; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peroxidase; Phagocytosis; Phagosomes; Protein Processing, Post-Translational; Respiratory Burst; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Characteristics of estrogen-induced peroxidase in mouse uterine luminal fluid.
Topics: Animals; Ascorbic Acid; Body Fluids; Chlorophenols; Cytochrome c Group; Diethylstilbestrol; Estradiol; Female; Glutathione; Hydrogen Peroxide; Lactoperoxidase; Mice; NADP; Peroxidase; Superoxide Dismutase; Tritium; Tyrosine; Uterus; Water | 1991 |
The peroxidase-catalyzed oxidation of enkephalins.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Enkephalin, Leucine; Enkephalin, Methionine; Horseradish Peroxidase; Kinetics; Lactoperoxidase; Oxidation-Reduction; Peroxidase; Peroxidases; Spectrophotometry, Ultraviolet; Tyrosine | 1991 |
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl.
Topics: Azides; Chloramines; Fibronectins; Fluorescence; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Molecular Weight; Neutrophils; Pancreatic Elastase; Peroxidase; Protein Denaturation; Tryptophan; Tyrosine | 1991 |
Rapid enzymatic analysis of plasma for tyrosine.
Topics: Autoanalysis; Buffers; Humans; Hydrogen-Ion Concentration; Monoamine Oxidase; Oxidoreductases Acting on CH-NH Group Donors; Peroxidase; Reproducibility of Results; Spectrophotometry; Tyrosine; Tyrosine Decarboxylase | 1990 |
Mueller-Hinton broth undergoes visible oxidative color changes in the presence of peroxidase and hydrogen peroxide.
Topics: Bacteriological Techniques; Color; Culture Media; Hydrogen Peroxide; Oxidation-Reduction; Peroxidase; Tyrosine | 1990 |
Metabolism of 35S- and 14C-labeled 1-methyl-2-mercaptoimidazole in vitro and in vivo.
Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Disulfides; Imidazoles; Iodides; Kinetics; Male; Methimazole; Peroxidase; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Thyroid Gland; Tyrosine | 1989 |
Generation of O2- and tyrosine cation-mediated chemiluminescence during the fertilization of sea urchin eggs.
Topics: Animals; Azides; Catalase; Cations; Fertilization; Free Radicals; Hydrogen Peroxide; Luminescence; Luminol; Ovum; Peroxidase; Sea Urchins; Sodium Azide; Spectrophotometry; Superoxide Dismutase; Superoxides; Tyrosine | 1989 |
The effect of thyroxine and related compounds on the aerobic myeloperoxidase--catalysed oxidation of NADH.
Topics: Aerobiosis; Catalysis; Humans; NAD; Oxidation-Reduction; Peroxidase; Spectrophotometry, Ultraviolet; Thyronines; Thyroxine; Tyrosine | 1988 |
The control of peroxidase-catalysed iodination and de-iodination.
Topics: Animals; Horseradish Peroxidase; Hydrogen Peroxide; Iodine; Iodine Radioisotopes; Lactoperoxidase; Neutrophils; Peroxidase; Peroxidases; Rats; Thyroid Gland; Thyroxine; Triiodothyronine; Tyrosine | 1981 |
Degradation and oxidation of methionine enkephalin by human neutrophils.
Topics: Azides; Biotransformation; Catalase; Endorphins; Enkephalin, Methionine; Enkephalins; Humans; In Vitro Techniques; Neutrophils; Oxidation-Reduction; Peroxidase; Superoxide Dismutase; Superoxides; Tyrosine | 1982 |
Oxidation of tyrosine to dopachrome by peroxidase isolated from murine melanoma.
Topics: Animals; Clone Cells; In Vitro Techniques; Indolequinones; Indoles; Isoenzymes; Melanins; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Peroxidase; Peroxidases; Quinones; Tyrosine | 1982 |
Distinct signal transduction through the tyrosine-containing domains of the granulocyte colony-stimulating factor receptor.
Topics: Animals; Base Sequence; Cell Differentiation; Cell Division; Gene Deletion; Granulocyte Colony-Stimulating Factor; Mice; Molecular Sequence Data; Neutrophils; Peroxidase; Point Mutation; Receptors, Granulocyte Colony-Stimulating Factor; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1995 |
Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils.
Topics: Amino Acid Sequence; Humans; Hypochlorous Acid; Molecular Sequence Data; Neutrophils; Oligopeptides; Peroxidase; Tyrosine | 1995 |
Isodityrosine cross-linking mediates insolubilization of cell walls in Chlamydomonas.
Topics: Amino Acid Sequence; Animals; Ascorbic Acid; Base Sequence; Cell Wall; Chlamydomonas reinhardtii; Cloning, Molecular; Cross-Linking Reagents; Epitopes; Glycoproteins; Hydrogen Peroxide; Molecular Sequence Data; Peroxidase; RNA, Messenger; Solubility; Tyrosine | 1993 |
Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein.
Topics: Ascorbic Acid; Catalysis; Free Radicals; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Neutrophils; Oxidation-Reduction; Peroxidase; Probucol; Substrate Specificity; Tyrosine; Vitamin E | 1994 |
Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.
Topics: Cells, Cultured; Chromatography, Liquid; Free Radicals; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Macrophages; Mass Spectrometry; Neutrophils; Oxidation-Reduction; Peroxidase; Spectrum Analysis; Tyrosine | 1993 |
Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.
Topics: Amino Acid Sequence; Cross-Linking Reagents; Dipeptides; Free Radicals; Humans; Molecular Sequence Data; Neutrophils; Oligopeptides; Oxidation-Reduction; Peroxidase; Serum Albumin, Bovine; Tyrosine | 1993 |
Chemiluminescence from bamboo shoot cut.
Topics: Image Processing, Computer-Assisted; Luminescent Measurements; Peroxidase; Poaceae; Tyrosine | 1993 |
Formation of a hydroxyl radical by the myeloperoxidase-NADH-oxygen system.
Topics: Aerobiosis; Catalase; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Kinetics; NAD; Oxygen; Peroxidase; Phenylalanine; Superoxide Dismutase; Tyrosine | 1993 |
Kinetics of oxidation of tyrosine and dityrosine by myeloperoxidase compounds I and II. Implications for lipoprotein peroxidation studies.
Topics: Animals; Catalysis; Cattle; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lipid Peroxidation; Lipoproteins; Peroxidase; Spectrometry, Fluorescence; Spectrophotometry; Spleen; Tyrosine | 1995 |
Neutrophils convert tyrosyl residues in albumin to chlorotyrosine.
Topics: Amino Acid Sequence; Humans; Hypochlorous Acid; In Vitro Techniques; Inflammation; Molecular Sequence Data; Neutrophils; Oligopeptides; Peroxidase; Serum Albumin; Tyrosine | 1996 |
p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes. A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase.
Topics: Acetaldehyde; Cells, Cultured; Chlorides; Chromatography, High Pressure Liquid; Fourier Analysis; Humans; Magnetic Resonance Spectroscopy; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Phenol; Superoxides; Tyrosine | 1996 |
Human phagocytes employ the myeloperoxidase-hydrogen peroxide system to synthesize dityrosine, trityrosine, pulcherosine, and isodityrosine by a tyrosyl radical-dependent pathway.
Topics: Free Radicals; Humans; Hydrogen Peroxide; Neutrophils; Oxidation-Reduction; Peroxidase; Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tyrosine | 1996 |
Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria.
Topics: Arginine; Bacteria; Blood Bactericidal Activity; Blotting, Western; Enzyme Induction; Enzyme Inhibitors; Humans; In Situ Hybridization; Interferon-gamma; Interleukin-1; Monokines; Neutrophils; Nitric Oxide Synthase; omega-N-Methylarginine; Peroxidase; Phagocytosis; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 1996 |
Human neutrophils employ chlorine gas as an oxidant during phagocytosis.
Topics: Chlorine; Gas Chromatography-Mass Spectrometry; Humans; Inflammation; Leukocytes; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytosis; Phagosomes; Tyrosine | 1996 |
Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL).
Topics: Animals; Antioxidants; Copper; Dexamethasone; Estradiol; Estrogen Antagonists; Free Radicals; Horseradish Peroxidase; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Peroxidase; Phagocytosis; Piperidines; Probucol; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Thiobarbituric Acid Reactive Substances; Thiophenes; Tyrosine | 1996 |
Involvement of peroxidase in chorion hardening in Aedes aegypti.
Topics: Aedes; Animals; Chorion; Egg Proteins; Female; Hydrogen Peroxide; Ovum; Peroxidase; Time Factors; Tyrosine | 1996 |
Chemiluminescence from human polymorphonuclear leukocytes activated with opsonized zymosan.
Topics: Humans; Hydrogen Peroxide; Luminescent Measurements; Neutrophils; Opsonin Proteins; Peroxidase; Tyrosine; Zymosan | 1997 |
Phenol-oxidizing enzymes: mechanisms and applications in biosensors.
Topics: Biosensing Techniques; Enzyme Inhibitors; Free Radicals; Laccase; Models, Chemical; Molecular Structure; Monophenol Monooxygenase; Oxidoreductases; Peroxidase; Phenols; Substrate Specificity; Tyrosine | 1997 |
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
Topics: Animals; Aorta; Arteriosclerosis; Cattle; Copper; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyl Radical; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine | 1997 |
Myeloperoxidase-dependent generation of a tyrosine peroxide by neutrophils.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Neutrophils; Oxidation-Reduction; Peroxidase; Peroxides; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1997 |
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
Topics: Aorta; Apolipoproteins B; Arteriosclerosis; Biomarkers; Chlorine; Humans; Hypochlorous Acid; Lipoproteins; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 1997 |
Oxidative tyrosylation of high density lipoprotein impairs biliary sterol secretion in rats.
Topics: Animals; Bile; Bile Acids and Salts; Cholesterol; Hydrogen Peroxide; Lipoproteins, HDL; Male; Oxidation-Reduction; Peroxidase; Rats; Rats, Sprague-Dawley; Tyrosine | 1997 |
p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues.
Topics: Acetaldehyde; Amino Acids; Animals; Cattle; Chlorides; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Inflammation; Lysine; Magnetic Resonance Spectroscopy; Neutrophils; Peroxidase; Phagocytes; Phenol; Proteins; Schiff Bases; Serum Albumin, Bovine; Tyrosine | 1997 |
What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
Topics: Biomarkers; Free Radicals; Humans; Molecular Structure; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrous Acid; Peroxidase; Superoxides; Tyrosine | 1997 |
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation.
Topics: Analysis of Variance; Aorta; Arteriosclerosis; Biomarkers; Calibration; Carbon; Carbon Isotopes; Catalysis; Chlorine; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypochlorous Acid; Inflammation; Lipoproteins, LDL; Male; Peroxidase; Sensitivity and Specificity; Tyrosine | 1997 |
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Topics: Animals; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Free Radical Scavengers; Immunoenzyme Techniques; Inflammation; Male; Melatonin; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Pleurisy; Rats; Rats, Sprague-Dawley; Tyrosine | 1997 |
Paracetamol catalyzes myeloperoxidase-initiated lipid oxidation in LDL.
Topics: Acetaminophen; Antioxidants; Ascorbic Acid; Azides; Catalase; Catalysis; Cyanides; Dimerization; Free Radical Scavengers; Humans; Hydrogen Peroxide; Lipid Peroxidation; Lipoproteins, LDL; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tyrosine | 1997 |
Role of multimerized porcine thyroglobulin in iodine storage.
Topics: Amino Acids; Animals; Diiodotyrosine; Disulfides; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Iodides; Iodine; Microscopy, Electron, Scanning; Monoiodotyrosine; Peroxidase; Pronase; Protein Conformation; Swine; Thyroglobulin; Thyroid Gland; Thyroxine; Triiodothyronine; Trypsin; Tyrosine | 1998 |
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cells, Cultured; Creatine Kinase; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Tyrosine | 1997 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway.
Topics: Aldehydes; Amino Acids; Chloramines; Chlorides; Humans; Hypochlorous Acid; Lysine; Mass Spectrometry; Models, Chemical; Neutrophils; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine | 1998 |
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.
Topics: Animals; Creatine Kinase; Cytokines; Dexamethasone; Disease Models, Animal; Dogs; Guanidines; Heart; Hemodynamics; Histocytochemistry; Inflammation; Interleukin-1; Isoenzymes; Leukocyte Count; Microspheres; Myocardium; Nitrates; Nitric Oxide; Peroxidase; Tyrosine; Ventricular Dysfunction, Left | 1998 |
Covalent cross-linking of immune complexes by oxygen radicals and nitrite.
Topics: Antigen-Antibody Complex; Catalysis; Cell Separation; Cross-Linking Reagents; Glucose Oxidase; Humans; Hydrogen Peroxide; Neutrophils; Nitrites; Nitrogen Dioxide; Peroxidase; Reactive Oxygen Species; Tyrosine | 1998 |
A kinetic model of the myeloperoxidase-hydrogen peroxide-chloride ion system in phagolysosomes.
Topics: Animals; Chlorides; Hydrogen Peroxide; Mammals; Models, Biological; Neutrophils; Oxidative Stress; Peroxidase; Peroxides; Phagosomes; Taurine; Tyrosine | 1998 |
Biochemical properties of human oral polymorphonuclear leukocytes.
Topics: Apoptosis; HL-60 Cells; Humans; Hydrogen Peroxide; Luminescent Measurements; Luminol; Molecular Weight; Mouth; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxides; Tyrosine | 1998 |
Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide.
Topics: Animals; Catalase; Catalysis; Horseradish Peroxidase; Hydrogen Peroxide; Hypochlorous Acid; Male; Myocardium; Nitrates; Nitrites; Peroxidase; Rats; Serum Albumin, Bovine; Tyrosine | 1998 |
Oxidation of guaiacol by myeloperoxidase: a two-electron-oxidized guaiacol transient species as a mediator of NADPH oxidation.
Topics: Biphenyl Compounds; Electrons; Guaiacol; Humans; Hydrogen Peroxide; Kinetics; NADP; Oxidation-Reduction; Peroxidase; Pyridines; Quinones; Superoxide Dismutase; Tetranitromethane; Tyrosine | 1998 |
Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase, and horseradish peroxidase.
Topics: Animals; Arteriosclerosis; Cattle; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Inflammation; Kinetics; Lactoperoxidase; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Pronase; Tyrosine | 1998 |
Detection of 3-chlorotyrosine in proteins exposed to neutrophil oxidants.
Topics: Blood Proteins; Chlorides; Chromatography, High Pressure Liquid; Electrochemistry; Fluorescence; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Oxidants; Peroxidase; Tyrosine | 1999 |
Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues.
Topics: Amino Acids; Arteriosclerosis; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Isotopes; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Phenylalanine; Proteins; Reference Standards; Tyrosine | 1999 |
Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis.
Topics: Animals; Colitis; Disease Models, Animal; Immunohistochemistry; Intercellular Adhesion Molecule-1; Intestinal Mucosa; Malondialdehyde; Mice; Neutrophils; Oxidative Stress; Permeability; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Severity of Illness Index; Time Factors; Trinitrobenzenesulfonic Acid; Tyrosine; Up-Regulation | 1999 |
Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin E-like antioxidant, in carrageenan-induced pleurisy.
Topics: Animals; Antioxidants; Benzofurans; Carrageenan; Cell Respiration; Energy Metabolism; Excipients; Immunohistochemistry; Lung; Macrophages, Alveolar; Malondialdehyde; Peroxidase; Pleurisy; Rats; Tyrosine; Vitamin E | 1999 |
Biochemical activities of extracts from Hypericum perforatum L. 2nd Communication: inhibition of metenkephaline- and tyrosine-dimerization.
Topics: Anthracenes; Chromatography, High Pressure Liquid; Depression, Chemical; Dimerization; Enkephalin, Methionine; Enzyme Inhibitors; Ericales; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Oxidants; Peroxidase; Perylene; Phenols; Plant Extracts; Tyrosine | 1999 |
Biochemical activities of extracts from Hypericum perforatum L. 3rd Communication: modulation of peroxidase activity as a simple method for standardization.
Topics: Chromatography, High Pressure Liquid; Dimerization; Enzyme Inhibitors; Ericales; Fertilizers; Horseradish Peroxidase; Hydrogen Peroxide; Indoleacetic Acids; Oxidants; Oxidation-Reduction; Peroxidase; Plant Extracts; Tyrosine | 1999 |
In vitro peroxidase oxidation induces stable dimers of beta-amyloid (1-42) through dityrosine bridge formation.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Chromatography, High Pressure Liquid; Dimerization; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Peroxidase; Spectrometry, Fluorescence; Tyrosine | 1999 |
Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages.
Topics: Acetaldehyde; Animals; Apolipoproteins E; Arteriosclerosis; Cell Line; Cholesterol Esters; Esterification; Humans; Hyperlipoproteinemia Type III; Hypochlorous Acid; Interferon-gamma; Lipoprotein Lipase; Lipoproteins, VLDL; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Peroxidase; Phenol; Poly I; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class A; Scavenger Receptors, Class B; Sterol O-Acyltransferase; Triglycerides; Tyrosine | 1999 |
Myeloperoxidase-catalyzed oxidation of tyrosine.
Topics: Animals; Cattle; Cross-Linking Reagents; Cysteine; Free Radicals; Glutathione; Kinetics; Methionine; Molecular Weight; Oxidants; Oxidation-Reduction; Peptides; Peroxidase; Sulfhydryl Reagents; Tyrosine | 1999 |
Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid.
Topics: Arteriosclerosis; Aspirin; Free Radical Scavengers; Free Radicals; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Phenols; Salicylic Acid; Tyrosine | 1999 |
Role of the distal phenylalanine 54 on the structure, stability, and ligand binding of Coprinus cinereus peroxidase.
Topics: Binding Sites; Coprinus; Enzyme Stability; Fungal Proteins; Glycine; Hydrogen-Ion Concentration; Imidazoles; Ligands; Mutagenesis, Site-Directed; Peroxidase; Phenylalanine; Sodium Fluoride; Spectrophotometry; Spectrum Analysis, Raman; Structure-Activity Relationship; Titrimetry; Tryptophan; Tyrosine; Valine | 1999 |
Role of interleukin-6 in a non-septic shock model induced by zymosan.
Topics: Animals; Antibodies, Monoclonal; Ascites; Ascitic Fluid; DNA Damage; Energy Metabolism; Injections, Intraperitoneal; Interleukin-6; Intestine, Small; Leukocyte Count; Lipid Peroxidation; Liver; Lung; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiple Organ Failure; NAD; Neutrophils; Nitrates; Nitrites; Oxidative Phosphorylation; Peritonitis; Peroxidase; Shock; Tyrosine; Zymosan | 1999 |
Inhaled nitric oxide reduces tyrosine nitration after lipopolysaccharide instillation into lungs of rats.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Instillation, Drug; Leukocyte Count; Lipopolysaccharides; Lung; Male; Nitric Oxide; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Tyrosine | 1999 |
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Topics: Animals; Benzamides; Complement Activation; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Free Radicals; Immunohistochemistry; Inflammation; Male; Niacinamide; Nitrates; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tyrosine; Zymosan | 1999 |
IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.
Topics: Animals; Antibodies, Monoclonal; Arterial Occlusive Diseases; Celiac Artery; Constriction; Cytokines; Ileum; Immunity, Innate; Intercellular Adhesion Molecule-1; Interleukin-6; Ischemia; Leukocyte Count; Lipid Peroxidation; Malondialdehyde; Mesenteric Artery, Superior; Mice; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Reperfusion Injury; Shock; Splanchnic Circulation; Tyrosine | 1999 |
Role of IL-6 in the pleurisy and lung injury caused by carrageenan.
Topics: Animals; Carrageenan; Cells, Cultured; Cytokines; Dinoprostone; DNA Damage; Enzyme Induction; Interleukin-6; Leukotriene B4; Lung; Macrophages; Male; Malondialdehyde; Mice; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Tyrosine | 1999 |
Oxidation of heparin-treated low density lipoprotein by peroxidases.
Topics: Antioxidants; Arteries; Arteriosclerosis; Binding Sites; Butylated Hydroxytoluene; Heparin; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Peroxidases; Proteoglycans; Thiobarbituric Acid Reactive Substances; Tunica Intima; Tyrosine | 1999 |
The protective role of endogenous melatonin in carrageenan-induced pleurisy in the rat.
Topics: Animals; Carrageenan; Cells, Cultured; Energy Metabolism; Lipid Peroxidation; Macrophages; Melatonin; Nitrates; Nitric Oxide; Peroxidase; Pleurisy; Rats; Tyrosine | 1999 |
The hydroxyl radical formation system in polymorphonuclear leukocytes.
Topics: Animals; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Neutrophils; Peroxidase; Phenylalanine; Swine; Tyrosine | 1999 |
Protective effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, against laryngeal injury in rats.
Topics: Animals; Benzamides; Enzyme Inhibitors; Immunohistochemistry; Intubation, Intratracheal; Laryngeal Mucosa; Larynx; Male; Neutrophils; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Tyrosine; Wounds and Injuries | 1999 |
Formation of nitric oxide-derived oxidants by myeloperoxidase in monocytes: pathways for monocyte-mediated protein nitration and lipid peroxidation In vivo.
Topics: Apolipoprotein B-100; Apolipoproteins B; Humans; Lipid Peroxides; Lipoproteins, LDL; Monocytes; Nitrates; Nitric Oxide; Oxidants; Peroxidase; Tyrosine | 1999 |
Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Metalloporphyrins; NAD; Nitrates; Peroxidase; Rats; Rats, Sprague-Dawley; Shock; Superoxide Dismutase; Tyrosine; Zymosan | 1999 |
Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Chemotaxis, Leukocyte; Endothelium, Vascular; Free Radical Scavengers; Ileal Diseases; Immunoenzyme Techniques; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Melatonin; Mesenteric Artery, Superior; Neutrophils; Oxidative Stress; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Tyrosine | 2000 |
Role of hyperbaric oxygen exposure in reduction of lipid peroxidation and in multiple organ failure induced by zymosan administration in the rat.
Topics: Animals; Hyperbaric Oxygenation; Lipid Peroxidation; Male; Malondialdehyde; Multiple Organ Failure; Peritonitis; Peroxidase; Rats; Rats, Sprague-Dawley; Tyrosine; Zymosan | 2000 |
p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima.
Topics: Acetaldehyde; Arteriosclerosis; Humans; Hydrogen Peroxide; Kinetics; Lipoproteins, LDL; Neutrophils; Peroxidase; Phenol; Phosphatidylethanolamines; Phospholipids; Tunica Intima; Tyrosine | 2000 |
Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Neutrophils; Nitrites; Oxidation-Reduction; Peroxidase; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet; Tyrosine | 2000 |
Biochemical model reactions indicative of inflammatory processes. Activities of extracts from Fraxinus excelsior and Populus tremula.
Topics: Animals; Antioxidants; Cells, Cultured; Chromatography, High Pressure Liquid; Enzymes; Free Radical Scavengers; Humans; Indicators and Reagents; Inflammation; Inflammatory Bowel Diseases; Lipoproteins, LDL; Lipoxygenase; Models, Biological; Nervous System Diseases; Oxidative Stress; Peroxidase; Plant Extracts; Plants, Medicinal; Respiratory Burst; Respiratory Tract Diseases; Tyrosine; Xanthine Oxidase | 2000 |
Role of myeloperoxidase in the neutrophil-induced oxidation of low density lipoprotein as studied by myeloperoxidase-knockout mouse.
Topics: Animals; Apolipoproteins B; Hydrogen Peroxide; Lipid Peroxidation; Lipoproteins, LDL; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Neutrophils; Nitrogen Compounds; Oxidation-Reduction; Peroxidase; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2000 |
Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Blood Pressure; Catalysis; Celiac Artery; Disease Models, Animal; Endothelium, Vascular; Ferric Compounds; Ileum; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rhodamines; Splanchnic Circulation; Tyrosine | 2000 |
Purification and characterization of chorion peroxidase from Aedes aegypti eggs.
Topics: Aedes; Amino Acid Sequence; Amino Acids; Animals; Chorion; Cross-Linking Reagents; Female; Horseradish Peroxidase; Molecular Weight; Ovum; Oxidation-Reduction; Peroxidase; Protein Denaturation; Sodium Dodecyl Sulfate; Solubility; Spectrophotometry; Substrate Specificity; Tyrosine | 2000 |
Beneficial effects of n-acetylcysteine on ischaemic brain injury.
Topics: Acetylcysteine; Animals; Brain; Brain Edema; Brain Ischemia; Free Radical Scavengers; Gerbillinae; Male; Malondialdehyde; Motor Activity; Nitric Oxide; Peroxidase; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Time Factors; Tyrosine | 2000 |
Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase.
Topics: Humans; Kinetics; Nitrates; Nitric Oxide; Oxidants; Peroxidase; Sputum; Superoxides; Tyrosine; Xanthine Oxidase | 2000 |
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.
Topics: Acute Kidney Injury; Animals; Cell Membrane Permeability; Cell Separation; Cells, Cultured; Chelating Agents; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Free Radical Scavengers; Hydrogen Peroxide; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Malondialdehyde; Necrosis; Oxidants; Oxidative Stress; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reperfusion Injury; Spin Labels; Tyrosine | 2000 |
Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Blood Volume; Dinoprost; Enzyme Activation; Hemodynamics; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Peroxidase; Poly(ADP-ribose) Polymerases; Resuscitation; Shock, Hemorrhagic; Sodium Chloride; Tyrosine | 2000 |
Myeloperoxidase and protein oxidation in cystic fibrosis.
Topics: Adult; Bronchi; Case-Control Studies; Cell Line; Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Synergism; Humans; Hydrogen Peroxide; Nitrates; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Peroxidases; Proteins; Respiratory System; Sputum; Trachea; Tyrosine | 2000 |
Effects of n-acetylcysteine in a rat model of ischemia and reperfusion injury.
Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Aorta; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Ileum; In Vitro Techniques; Intercellular Adhesion Molecule-1; Leukocyte Count; Lipid Peroxidation; Male; Malondialdehyde; Nitrates; Nitrites; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splenic Artery; Tyrosine; Vasodilation | 2000 |
Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury.
Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Edema; Cerebral Arteries; Cyclic N-Oxides; Free Radical Scavengers; Gerbillinae; Hippocampus; Lipid Peroxides; Male; Malondialdehyde; Motor Activity; Neutrophil Infiltration; Nitrates; Nitrites; Peroxidase; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Spin Labels; Survival Analysis; Tyrosine | 2000 |
Mercaptoethylguanidine attenuates inflammation in bacterial meningitis in rabbits.
Topics: Animals; Brain; Enzyme Inhibitors; Guanidines; Immunoenzyme Techniques; Male; Malondialdehyde; Meningitis, Bacterial; Meningitis, Meningococcal; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Peroxidase; Proteins; Rabbits; Streptococcal Infections; Streptococcus agalactiae; Tyrosine | 2000 |
The tyrosine kinase inhibitor tyrphostin AG 126 reduced the development of colitis in the rat.
Topics: Animals; Body Weight; Colitis; Cyclooxygenase 2; Cytokines; Enzyme Inhibitors; Isoenzymes; Lipid Peroxidation; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins | 2000 |
Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis.
Topics: Animals; Benzenesulfonates; Body Weight; Cell Membrane Permeability; Colitis; Colon; Cyclic N-Oxides; Free Radical Scavengers; Immunohistochemistry; Intestinal Mucosa; Lipid Peroxidation; Male; Neutrophil Infiltration; Organ Size; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spin Labels; Spleen; Survival Rate; Tyrosine | 2000 |
Protective effects of melatonin in ischemic brain injury.
Topics: Animals; Brain; Brain Edema; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Gerbillinae; Immunoenzyme Techniques; Male; Malondialdehyde; Melatonin; Motor Activity; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Tyrosine | 2000 |
Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan.
Topics: Animals; Carrageenan; Cells, Cultured; DNA Damage; Enzyme Activation; Exudates and Transudates; Immunohistochemistry; Lipid Peroxidation; Lung; Macrophages; Male; Malondialdehyde; Mice; Mice, Knockout; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Pleura; Pleurisy; Poly(ADP-ribose) Polymerases; Tyrosine | 2000 |
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions.
Topics: Acetaldehyde; Antioxidants; Aorta; Arteriosclerosis; Chlorides; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lipoproteins, LDL; Lysine; Peroxidase; Phenol; Schiff Bases; Solubility; Tunica Intima; Tyrosine; Water | 2000 |
Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies.
Topics: Antibodies, Antineutrophil Cytoplasmic; Genistein; Humans; In Vitro Techniques; Kinetics; Mitogen-Activated Protein Kinases; Myeloblastin; Naphthalenes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Peroxidase; Phosphorylation; Respiratory Burst; Serine Endopeptidases; Signal Transduction; Staurosporine; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterial Occlusive Diseases; Catalysis; Cytokines; Fluorescent Antibody Technique; Ileum; Leukocyte Count; Male; Malondialdehyde; Manganese; Nitrates; Nitrites; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Splanchnic Circulation; Superoxide Dismutase; Superoxides; Tyrosine | 2001 |
Melatonin reduces dinitrobenzene sulfonic acid-induced colitis.
Topics: Animals; Colitis; Colon; Dinitrofluorobenzene; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Melatonin; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; P-Selectin; Peroxidase; Poly Adenosine Diphosphate Ribose; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
p-Hydroxyphenylacetaldehyde, the major product of tyrosine oxidation by the activated myeloperoxidase system can act as an antioxidant in LDL.
Topics: Acetaldehyde; Antioxidants; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Endothelium, Vascular; Free Radical Scavengers; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Ions; Lipid Metabolism; Lipoproteins, LDL; Neutrophils; Oxygen; Peroxidase; Phenol; Protein Binding; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine; Umbilical Veins | 2001 |
Increased atherosclerosis in myeloperoxidase-deficient mice.
Topics: Animals; Arteriosclerosis; Candida albicans; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 2001 |
Structural and biochemical analysis of the parasite Gordius villoti (Nematomorpha, Gordiacea) cuticle.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Collagenases; Electrophoresis, Polyacrylamide Gel; Epithelium; Helminths; Image Processing, Computer-Assisted; Microscopy, Electron; Microscopy, Video; Peroxidase; Spectrophotometry; Tyrosine; Ultraviolet Rays | 2000 |
Calpain inhibitor I reduces colon injury caused by dinitrobenzene sulphonic acid in the rat.
Topics: Adenosine Diphosphate Ribose; Analysis of Variance; Animals; Cysteine Proteinase Inhibitors; Dinitrobenzenes; Glycoproteins; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; P-Selectin; Peroxidase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonic Acids; Tyrosine; Up-Regulation | 2001 |
Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase, and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells.
Topics: Aniline Compounds; Animals; Antioxidants; Blotting, Western; Cattle; Cell Death; Enzyme Inhibitors; Epithelial Cells; Female; Free Radical Scavengers; Histidine; L-Lactate Dehydrogenase; Lipopolysaccharides; Mammary Glands, Animal; Molsidomine; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine | 2001 |
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
Topics: Acetylcysteine; Animals; Blotting, Western; Carrageenan; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Erythrocytes; Free Radical Scavengers; I-kappa B Proteins; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lung; Macrophages; Male; Malondialdehyde; Neutrophils; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Colon epithelial cell death in 2,4,6-trinitrobenzenesulfonic acid-induced colitis is associated with increased inducible nitric-oxide synthase expression and peroxynitrite production.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Death; Colitis; Colon; Disease Models, Animal; Epithelial Cells; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lysine; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxides; Trinitrobenzenesulfonic Acid; Tyrosine | 2001 |
Role of peroxynitrite in macrophage microbicidal mechanisms in vivo revealed by protein nitration and hydroxylation.
Topics: Animals; Carbon Dioxide; Carbonates; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxylation; Leishmania infantum; Leishmaniasis; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Fluorescence; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Peroxynitrous Acid; Tyrosine | 2001 |
Protein tyrosine nitration in cytokine-activated murine macrophages. Involvement of a peroxidase/nitrite pathway rather than peroxynitrite.
Topics: Animals; Cell Line; Cytokines; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Free Radical Scavengers; Hydrogen Peroxide; Immunoblotting; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitrates; Nitric Oxide; Nitrites; Nitrogen; Oxygen; Peroxidase; Recombinant Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; Zymosan | 2001 |
Chlorination of N-acetyltyrosine with HOCl, chloramines, and myeloperoxidase-hydrogen peroxide-chloride system.
Topics: Chloramines; Chlorides; Chlorine; Chromatography, High Pressure Liquid; Granulocytes; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; Peroxidase; Protein Binding; Time Factors; Tyrosine | 2001 |
Inducible nitric oxide synthase knockout mice exhibit resistance to the multiple organ failure induced by zymosan.
Topics: Animals; Enzyme Inhibitors; Exudates and Transudates; Guanidines; Lipid Peroxidation; Liver; Lung; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Multiple Organ Failure; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peritonitis; Peroxidase; Poly(ADP-ribose) Polymerases; Rhodamines; Shock; Tyrosine; Zymosan | 2001 |
Effect of N-acetylcysteine on gentamicin-mediated nephropathy in rats.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Gentamicins; Kidney; Male; Malondialdehyde; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Tyrosine | 2001 |
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
Topics: Animals; Benzamides; Enzyme Inhibitors; Immunohistochemistry; Interleukin-10; Interleukin-12; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocardium; NAD; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tissue Extracts; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs.
Topics: Animals; Endothelium, Vascular; Immunoblotting; Immunoenzyme Techniques; Lipopolysaccharides; Liver; Lung; Macrophages; Male; Molsidomine; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Sprague-Dawley; Spleen; Superoxides; Tyrosine | 2001 |
A kinetic analysis of the catalase activity of myeloperoxidase.
Topics: Catalase; Catalysis; Humans; Hydrogen Peroxide; Kinetics; Leukocytes; Models, Chemical; Neutrophils; Peroxidase; Tryptophan; Tyrosine | 2001 |
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.
Topics: Animals; Bromine; Chlorine; Disease Models, Animal; HL-60 Cells; Humans; Hypochlorous Acid; Ions; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxidants; Peroxidase; Sepsis; Tyrosine | 2001 |
Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite.
Topics: Animals; Female; Free Radical Scavengers; Hydrogen Peroxide; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide; Nitrites; Peroxidase; Peroxynitrous Acid; Propionibacterium acnes; Proteins; Superoxides; Thioglycolates; Time Factors; Tyrosine | 2001 |
Myeloperoxidase-catalyzed 3-chlorotyrosine formation in dialysis patients.
Topics: Adult; Aged; Blood Proteins; Female; Gas Chromatography-Mass Spectrometry; Humans; Leukocytes; Male; Middle Aged; Oxidative Stress; Peroxidase; Phagocytes; Renal Dialysis; Renal Insufficiency; Tyrosine | 2001 |
Chlorination of bacterial and neutrophil proteins during phagocytosis and killing of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Chlorine; Chromatography, Gas; Dose-Response Relationship, Drug; Hypochlorous Acid; Mass Spectrometry; Neutrophils; Oxidants; Peroxidase; Phagocytosis; Protein Binding; Protein Structure, Tertiary; Staphylococcus aureus; Temperature; Time Factors; Tyrosine | 2002 |
Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis.
Topics: Animals; Body Weight; Colitis; Colon; Cytokines; Enzyme Activation; Free Radical Scavengers; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Manganese; Organometallic Compounds; P-Selectin; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Survival Analysis; Time Factors; Tyrosine | 2001 |
Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration.
Topics: Animals; Biological Transport; Cell Degranulation; Endothelium, Vascular; Extracellular Matrix Proteins; Glycosaminoglycans; Humans; Mice; Mice, Inbred C57BL; Neutrophils; Nitrogen Dioxide; Peroxidase; Rabbits; Rats; Tyrosine | 2001 |
Lack of effect of glycoprotein IIb/IIIa blockade on myocardial platelet or polymorphonuclear leukocyte accumulation and on infarct size after transient coronary occlusion in pigs.
Topics: Acetates; Animals; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Neutrophils; Peroxidase; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Tyrosine | 2002 |
Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; DNA, Complementary; Granulocyte Colony-Stimulating Factor; Mice; Neutrophils; Peroxidase; Phosphorylation; src-Family Kinases; Tyrosine | 2002 |
Deficiency of myeloperoxidase increases infarct volume and nitrotyrosine formation in mouse brain.
Topics: Animals; Brain; Brain Infarction; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peroxidase; Peroxynitrous Acid; Reperfusion Injury; Time Factors; Tyrosine | 2002 |
Defects in leukocyte-mediated initiation of lipid peroxidation in plasma as studied in myeloperoxidase-deficient subjects: systematic identification of multiple endogenous diffusible substrates for myeloperoxidase in plasma.
Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Diffusion; Estradiol; Gas Chromatography-Mass Spectrometry; Humans; Leukocytes; Lipid Metabolism; Lipid Peroxidation; Neutrophils; Nitrites; Peroxidase; Plasma; Substrate Specificity; Thiocyanates; Tyrosine | 2002 |
A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.
Topics: Animals; Candidiasis; Hydrogen Peroxide; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrites; Nitrogen Dioxide; Oxidation-Reduction; Peroxidase; Reactive Nitrogen Species; Tyrosine | 2002 |
Phenolic compounds and related enzymes are not rate-limiting in browning development of fresh-cut potatoes.
Topics: Catechol Oxidase; Chlorogenic Acid; Chromatography, High Pressure Liquid; Food Handling; Kinetics; Maillard Reaction; Peroxidase; Phenols; Phenylalanine Ammonia-Lyase; Solanum tuberosum; Species Specificity; Time Factors; Tyrosine | 2002 |
Myeloperoxidase produces nitrating oxidants in vivo.
Topics: Animals; Klebsiella Infections; Klebsiella pneumoniae; Mice; Peritonitis; Peroxidase; Reactive Nitrogen Species; Tyrosine | 2002 |
Early inflammatory response to asbestos exposure in rat and hamster lungs: role of inducible nitric oxide synthase.
Topics: Animals; Asbestos, Crocidolite; Asbestosis; Body Weight; Bronchoalveolar Lavage Fluid; Cell Count; Cricetinae; Disease Models, Animal; Inhalation Exposure; Intubation, Intratracheal; Lung; Mesocricetus; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen; Peroxidase; Rats; RNA, Messenger; Species Specificity; Thiobarbituric Acid Reactive Substances; Tyrosine | 2002 |
Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis.
Topics: Bacterial Proteins; Chlorides; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Nitrites; Peroxidase; Phagocytosis; Tyrosine | 2002 |
Protein nitration is predominantly mediated by a peroxynitrite-dependent pathway in cultured human leucocytes.
Topics: Aniline Compounds; Cells, Cultured; Extracellular Space; Humans; Leukocytes; Metalloporphyrins; Nitrates; Peroxidase; Peroxynitrous Acid; Proteins; Spermine; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo.
Topics: Animals; Cardiotonic Agents; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Manganese; Molecular Mimicry; Myocardial Ischemia; Myocardial Reperfusion Injury; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine | 2002 |
Dual role of inducible nitric oxide synthase in acute asbestos-induced lung injury.
Topics: Acute Disease; Animals; Asbestos; Asbestosis; Bronchoalveolar Lavage Fluid; Chemotaxis; Enzyme Induction; Gene Expression Regulation; Inflammation; L-Lactate Dehydrogenase; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Peroxidase; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice.
Topics: Amylases; Animals; Ceruletide; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Lipase; Lipid Peroxidation; Male; Mice; Mice, Knockout; Microscopy, Fluorescence; P-Selectin; Pancreas; Pancreatitis; Peroxidase; Phenotype; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Concurrent formation of peroxynitrite with the expression of inducible nitric oxide synthase in the brain during middle cerebral artery occlusion and reperfusion in rats.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Chemotaxis, Leukocyte; Disease Models, Animal; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Reaction Time; Reperfusion Injury; Tyrosine | 2002 |
Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Cyclic N-Oxides; Kidney Diseases; Kidney Tubules; Lipopolysaccharides; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; P-Selectin; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Spin Labels; Staphylococcus aureus; Teichoic Acids; Tyrosine | 2002 |
Myeloperoxidase-associated tyrosine nitration after intratracheal administration of lipopolysaccharide in rats.
Topics: Administration, Inhalation; Alkylating Agents; Animals; Antibody Specificity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Cyclophosphamide; Immunohistochemistry; Leukocyte Count; Lipopolysaccharides; Lung; Male; Neutropenia; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tyrosine | 2002 |
Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases.
Topics: Animals; Blood Vessels; Coronary Vessels; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Peroxidase; Tyrosine | 2002 |
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat.
Topics: Animals; Calpain; Cell Movement; Cyclooxygenase 2; Dose-Response Relationship, Drug; Glycoproteins; Immunohistochemistry; Intestinal Mucosa; Intestines; Isoenzymes; Liver; Lung; Male; Malondialdehyde; Multiple Organ Failure; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peritoneum; Peritonitis; Peroxidase; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tyrosine; Zymosan | 2002 |
Urinary tract infection in iNOS-deficient mice with focus on bacterial sensitivity to nitric oxide.
Topics: Animals; Antibodies; Colony Count, Microbial; Escherichia coli; Escherichia coli Infections; Female; Genotype; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nephritis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peroxidase; Peroxynitrous Acid; Tyrosine; Urinary Tract Infections | 2003 |
Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats.
Topics: Animals; Behavior, Animal; Brain; Cell Count; Cerebrovascular Circulation; Glycoproteins; Hypoxia-Ischemia, Brain; Immunohistochemistry; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Nervous System Diseases; Neuroprotective Agents; Neutrophils; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Trypsin Inhibitors; Tyrosine | 2003 |
Redox properties of the couples compound I/compound II and compound II/native enzyme of human myeloperoxidase.
Topics: Humans; Nitrites; Oxidation-Reduction; Peroxidase; Spectrometry, Fluorescence; Tyrosine | 2003 |
Immunohistochemical artifact for nitrotyrosine in eosinophils or eosinophil containing tissue.
Topics: Artifacts; Chromatography, High Pressure Liquid; Dithionite; Eosinophils; Gastric Mucosa; Humans; Hydrogen Peroxide; Immunoenzyme Techniques; Nitrogen Compounds; Ovalbumin; Oxidants; Oxidation-Reduction; Periodic Acid; Peroxidase; Tyrosine | 2002 |
Oxidation of Cu, Zn-superoxide dismutase by the myeloperoxidase/hydrogen peroxide/chloride system: functional and structural effects.
Topics: Animals; Cattle; Copper; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Hydrazines; Hydrogen Peroxide; Hypochlorous Acid; Isoelectric Focusing; Lysine; Methionine; Oxidation-Reduction; Peroxidase; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Tyrosine; Zinc | 2002 |
3-Chlorotyrosine as a marker of protein damage by myeloperoxidase in tracheal aspirates from preterm infants: association with adverse respiratory outcome.
Topics: Biomarkers; Chronic Disease; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Neutrophils; Oxidative Stress; Peroxidase; Respiratory Distress Syndrome, Newborn; Trachea; Tyrosine; Ureaplasma Infections; Ureaplasma urealyticum | 2003 |
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury.
Topics: Animals; Creatinine; Enzyme Inhibitors; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Poly Adenosine Diphosphate Ribose; Rats; Rats, Wistar; Reperfusion Injury; Sulfides; Tyrosine; Urea | 2003 |
Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium.
Topics: Calcium; Calcium Signaling; CD11 Antigens; Cell Adhesion; Chemotaxis; Cytosol; Enzyme Activation; Humans; Intercellular Signaling Peptides and Proteins; Lactoferrin; Lysophosphatidylcholines; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Pancreatic Elastase; Peroxidase; Pertussis Toxin; Phosphorylation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Peptide; Serine; Tyrosine | 2003 |
The nature of heme/iron-induced protein tyrosine nitration.
Topics: Animals; Brain; Heme; Hemeproteins; Hydrogen Peroxide; Kidney; Kinetics; Liver; Male; Mice; Muscle, Skeletal; Myocardium; Nitrates; Organ Specificity; Peroxidase; Sodium Nitrite; Tyrosine | 2003 |
Myeloperoxidase has directly-opposed effects on nitration reaction--study on myeloperoxidase-deficient patient and myeloperoxidase-knockout mice.
Topics: Adult; Animals; Enzyme-Linked Immunosorbent Assay; Humans; Hydrogen Peroxide; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitrites; Nitrogen Dioxide; Nitrosation; Oxidation-Reduction; Peroxidase; Reactive Nitrogen Species; Time Factors; Tyrosine | 2003 |
Inhibition of myeloperoxidase-catalyzed tyrosylation by phenolic antioxidants in vitro.
Topics: Antioxidants; Buffers; Chromatography, High Pressure Liquid; Coumaric Acids; Curcumin; Enzyme Inhibitors; Gallic Acid; Peroxidase; Phenols; Quercetin; Spectrometry, Fluorescence; Tyrosine | 2003 |
Critical role of reactive nitrogen species in lung ischemia-reperfusion injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Chemokines; Disease Models, Animal; Immunohistochemistry; Inflammation Mediators; Macrophages, Alveolar; Male; Models, Cardiovascular; NF-kappa B; Peroxidase; Peroxynitrous Acid; Rats; Rats, Long-Evans; Reactive Nitrogen Species; Reperfusion Injury; Respiratory Distress Syndrome; Severity of Illness Index; Statistics as Topic; Transcription Factor AP-1; Transcriptional Activation; Tyrosine | 2003 |
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice.
Topics: Animals; Antioxidants; Blotting, Western; Chemotaxis, Leukocyte; Disease Models, Animal; Drug Evaluation, Preclinical; Immunohistochemistry; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Multiple Organ Failure; Neutrophils; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Poly(ADP-ribose) Polymerases; Pyrrolidines; Random Allocation; Thiocarbamates; Time Factors; Tyrosine; Zymosan | 2003 |
Protein nitration in rat lungs during hyperoxia exposure: a possible role of myeloperoxidase.
Topics: Amino Acid Sequence; Animals; Bronchoalveolar Lavage Fluid; Cell Line; Edema; Hemorrhage; Hyperoxia; Lung; Macrophages, Alveolar; Neutrophils; Nitrates; Nitrites; Peptide Fragments; Peroxidase; Proteins; Pulmonary Surfactant-Associated Protein A; Rats; Respiratory Mucosa; Time Factors; Tyrosine | 2003 |
Rapid formation of compound II and a tyrosyl radical in the Y229F mutant of Mycobacterium tuberculosis catalase-peroxidase disrupts catalase but not peroxidase function.
Topics: Bacterial Proteins; Catalase; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Gene Expression; Heme; Iron; Mutagenesis; Mycobacterium tuberculosis; Peroxidase; Peroxidases; Structure-Activity Relationship; Transfection; Tyrosine | 2003 |
Histidine 386 and its role in cyclooxygenase and peroxidase catalysis by prostaglandin-endoperoxide H synthases.
Topics: Animals; Binding Sites; Catalysis; COS Cells; Crystallography, X-Ray; Cyclooxygenase 1; Eicosanoids; Heme; Histidine; Isoenzymes; Ligands; Linoleic Acid; Microsomes; Models, Chemical; Mutation; Oxygen; Peroxidase; Plasmids; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Sheep; Time Factors; Transfection; Tyrosine; Ultraviolet Rays | 2003 |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Epoxy Compounds; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-1; Intestinal Mucosa; Intestines; Ligands; Male; Malondialdehyde; Peroxidase; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reperfusion Injury; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vasodilator Agents | 2003 |
Oxidation of proteins by tyrosinase and peroxidase.
Topics: Amino Acids; Catechol Oxidase; Dihydroxyphenylalanine; Monophenol Monooxygenase; Oxidation-Reduction; Oxidoreductases; Peroxidase; Peroxidases; Proteins; Tyrosine | 1953 |
[The action of a plant peroxidase on various hydroxyphenyl amino acids: tyrosine, thyronine, and certain of their iodized or hydroxylated derivatives].
Topics: Amino Acids; Coloring Agents; Hydroxylation; Oxidoreductases; Peroxidase; Peroxidases; Phenylalanine; Thyronines; Tyrosine | 1958 |
The oxidation of tyramine, tyrosine, and related compounds by peroxidase.
Topics: Coloring Agents; Oxidation-Reduction; Oxidoreductases; Peroxidase; Peroxidases; Tyramine; Tyrosine | 1959 |
Studies on the biosynthesis of iodotyrosines: the relationship of peroxidase, catalase and cytochrome oxidase.
Topics: Catalase; Cytochromes; Electron Transport Complex IV; Iodides; Iodine; Monoiodotyrosine; Oxidoreductases; Peroxidase; Peroxidases; Tyrosine | 1962 |
Peroxidase-catalysed iodination and deiodination of iodotyrosines and iodothyronines.
Topics: Catalysis; Halogenation; Iodides; Monoiodotyrosine; Peroxidase; Peroxidases; Thyronines; Tyrosine | 1963 |
COLUMN-CHROMATOGRAPHIC SEPARATION OF A PEROXIDASE AND AN IODINASE IN SOLUBILIZED BEEF-THYROID PREPARATIONS.
Topics: Alkaloids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography; Glucose; Glucose Oxidase; Hydrogen Peroxide; Iodide Peroxidase; Manganese; NAD; Oxidoreductases; Pancreatic Extracts; Pancreatin; Peroxidase; Peroxidases; Phenols; Research; Sulfites; Thyroid Gland; Thyrotropin; Tyrosine | 1965 |
Myeloperoxidase-positive inflammatory cells participate in bile duct damage in primary biliary cirrhosis through nitric oxide-mediated reactions.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Bile Ducts; Epithelial Cells; Humans; Liver Cirrhosis, Biliary; Macrophages; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Tyrosine | 2003 |
Protective effects of anthocyanins from blackberry in a rat model of acute lung inflammation.
Topics: Acute Disease; Animals; Anthocyanins; Carrageenan; Dinoprostone; Exudates and Transudates; Fruit; Glucosides; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Lung; Male; Malondialdehyde; Neutrophils; Nitrates; Nitrites; Peroxidase; Plant Extracts; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 2003 |
Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis.
Topics: Amylases; Animals; Antioxidants; Blotting, Western; Ceruletide; Edema; I-kappa B Proteins; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Lipase; Lipid Peroxidation; Male; Mice; Necrosis; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Pancreatitis; Peroxidase; Pyrrolidines; Rats; Thiocarbamates; Tyrosine; Up-Regulation | 2003 |
Bicarbonate enhances alpha-synuclein oligomerization and nitration: intermediacy of carbonate radical anion and nitrogen dioxide radical.
Topics: alpha-Synuclein; Anions; Bicarbonates; Cyclic N-Oxides; Dimerization; Free Radicals; Hydrogen Peroxide; Hydroxylation; Liposomes; Nerve Tissue Proteins; Nitric Oxide Donors; Nitrogen Dioxide; Nitrogen Oxides; Oxidation-Reduction; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Synucleins; Tyrosine | 2004 |
Calpain inhibitor I reduces intestinal ischemia-reperfusion injury in the rat.
Topics: Animals; Blood Pressure; Blotting, Western; Cysteine Proteinase Inhibitors; Glycoproteins; I-kappa B Proteins; Ileum; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Malondialdehyde; Neutrophils; NF-KappaB Inhibitor alpha; P-Selectin; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Shock; Splanchnic Circulation; Time Factors; Tyrosine | 2004 |
Cytochrome c: a catalyst and target of nitrite-hydrogen peroxide-dependent protein nitration.
Topics: Animals; Catalysis; Cattle; Cytochromes c; Horses; Humans; Hydrogen Peroxide; Jurkat Cells; Mitochondria, Liver; Myocardium; Nitrates; Nitrites; Peroxidase; Phenylacetates; Rats; Recombinant Proteins; Serum Albumin, Bovine; Superoxide Dismutase; Tyrosine | 2004 |
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Cytokines; Dinoprostone; Edema; Exudates and Transudates; Immunohistochemistry; Isoenzymes; Lipid Peroxidation; Lung; Male; Neutrophil Infiltration; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tyrosine | 2004 |
Albumin oxidation to diverse radicals by the peroxidase activity of Cu,Zn-superoxide dismutase in the presence of bicarbonate or nitrite: diffusible radicals produce cysteinyl and solvent-exposed and -unexposed tyrosyl radicals.
Topics: Antioxidants; Bicarbonates; Cysteine; Diffusion; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Kinetics; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Serum Albumin, Bovine; Solvents; Spin Trapping; Sulfhydryl Compounds; Superoxide Dismutase; Tyrosine | 2004 |
The protective effects of early treatment with propofol on endotoxin-induced acute lung injury in rats.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Blotting, Western; Hemodynamics; Lipopolysaccharides; Lung; Male; Malondialdehyde; Nitric Oxide; Organ Size; Peroxidase; Propofol; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome; Reverse Transcriptase Polymerase Chain Reaction; Survival Rate; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation.
Topics: Animals; Carrageenan; Disease Models, Animal; Enzyme Inhibitors; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-1beta; Lung; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peptide Fragments; Peroxidase; Pleuropneumonia; Pneumonia; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Sulfides; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
[Peroxidase action of ascorbic action on tyrosine].
Topics: Ascorbic Acid; Carbohydrate Metabolism; Humans; Oxidoreductases; Peroxidase; Peroxidases; Tyrosine | 1951 |
Nitrotyrosine, dityrosine, and nitrotryptophan formation from metmyoglobin, hydrogen peroxide, and nitrite.
Topics: Hydrogen Peroxide; Methemoglobin; Metmyoglobin; Myoglobin; Nitrites; Peroxidase; Peroxynitrous Acid; Tryptophan; Tyrosine | 2004 |
(-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors.
Topics: Animals; Azoles; Blood Urea Nitrogen; Catechin; Copper; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Isoindoles; Japan; Kidney; Lipopolysaccharides; Lysine; Male; Nitric Oxide; Organoselenium Compounds; Peroxidase; Phytotherapy; Plant Extracts; Plant Roots; Proteinuria; Rats; Rats, Wistar; Reperfusion Injury; Rheum; Superoxide Dismutase; Tyrosine; Uric Acid; Zinc | 2004 |
Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; CD11 Antigens; Cell Movement; Disease Models, Animal; Disease Progression; Female; Integrin alpha Chains; Lipid Peroxidation; Macrophages; Neutrophil Infiltration; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Proteins; Rats; Rats, Wistar; Spinal Cord Injuries; Thiobarbituric Acid Reactive Substances; Tyrosine | 2004 |
Nitric oxide-derived species in synovial fluid from patients with juvenile idiopathic arthritis.
Topics: Adolescent; Adult; Arthritis, Juvenile; Child; Child, Preschool; Female; Humans; Leukocytes, Mononuclear; Macrophage Activation; Male; Nitric Oxide; Peroxidase; Reactive Nitrogen Species; Superoxides; Synovial Fluid; Tyrosine | 2004 |
Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.
Topics: Animals; Celiac Artery; Disease Models, Animal; Intercellular Adhesion Molecule-1; Intestine, Small; Ischemia; Isoquinolines; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Solubility; Tyrosine; Water | 2004 |
Methylguanidine reduces the development of non septic shock induced by zymosan in mice.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Exudates and Transudates; Immunohistochemistry; Intestinal Mucosa; Intestines; Kidney; Lipid Peroxidation; Lung; Male; Methylguanidine; Mice; Neutrophils; Pancreas; Peritonitis; Peroxidase; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Shock; Tyrosine; Zymosan | 2004 |
Inhibition of poly(ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitized Guinea pigs.
Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Bronchoalveolar Lavage Fluid; Enzyme Inhibitors; Guinea Pigs; Immunohistochemistry; Isoquinolines; Lung; Male; Malondialdehyde; Mast Cells; Nitric Oxide; Ovalbumin; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Respiratory Mechanics; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biotransformation; Catalase; Free Radical Scavengers; Isoniazid; Mycobacterium bovis; Mycobacterium tuberculosis; Nitric Oxide; Oxidoreductases; Peroxidase; Peroxynitrous Acid; Prodrugs; Spin Trapping; Tyrosine | 2004 |
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
Topics: Arteries; Arteriosclerosis; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Epitopes; Gas Chromatography-Mass Spectrometry; Humans; Immunohistochemistry; Inflammation; Lipid Peroxides; Lipoproteins, HDL; Mass Spectrometry; Nitric Oxide; Nitrogen; Oxygen; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Taurine; Time Factors; Tunica Intima; Tyrosine | 2004 |
Erythropoietin reduces the development of experimental inflammatory bowel disease.
Topics: Animals; Benzenesulfonates; Colitis; Erythropoietin; Immunohistochemistry; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Interleukin-1; Intestinal Mucosa; Male; Mice; Neutrophil Infiltration; Peroxidase; Poly Adenosine Diphosphate Ribose; Recombinant Proteins; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease.
Topics: Aged; Animals; Aorta; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blotting, Western; Cardiovascular Diseases; Catalysis; Cell Line; Cholesterol; Cohort Studies; Female; Femoral Artery; Humans; Lipoproteins, HDL; Macrophages; Male; Mice; Middle Aged; Nitro Compounds; Oxidation-Reduction; Peroxidase; Tyrosine | 2004 |
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Arteries; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Chromatography, Liquid; Humans; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Peroxidase; Tyrosine | 2004 |
American Chemical Society meeting. Enzyme deactivates heart-friendly HDL.
Topics: Animals; Apolipoprotein A-I; Biomarkers; Cardiovascular Diseases; Cholesterol; Humans; Lipoproteins, HDL; Magnetic Resonance Imaging; Oxidation-Reduction; Peroxidase; Risk Factors; Tyrosine | 2004 |
WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock.
Topics: Animals; Blood Pressure; Ileum; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-1; Male; Neutrophils; P-Selectin; Peroxidase; Peroxisome Proliferators; Poly(ADP-ribose) Polymerases; Pyrimidines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Shock; Splanchnic Circulation; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2004 |
Inducible peroxidases mediate nitration of anopheles midgut cells undergoing apoptosis in response to Plasmodium invasion.
Topics: 3,3'-Diaminobenzidine; Animals; Anopheles; Apoptosis; Benzidines; Catalysis; Cell Death; Chromogenic Compounds; Dactinomycin; Dose-Response Relationship, Drug; Female; Hydrogen Peroxide; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Models, Biological; NADPH Oxidases; Nitric Oxide Synthase; Nitrogen; Nucleic Acid Synthesis Inhibitors; Oxygen; Peroxidase; Peroxidases; Phagocytosis; Plasmodium berghei; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Time Factors; Tyrosine | 2004 |
N-acetylcysteine inhibits peroxynitrite-mediated damage in oleic acid-induced lung injury.
Topics: Acetylcysteine; Animals; Female; Lung; Malondialdehyde; Microscopy; Oleic Acid; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine | 2004 |
Abnormal cardiac wall motion and early matrix metalloproteinase activity.
Topics: Animals; Collagen; Dansyl Compounds; Dogs; Female; Fibrinolysin; Heart; Heart Rate; Indicators and Reagents; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Contraction; Myocardium; Nitrogen; Pacemaker, Artificial; Peroxidase; Tyrosine | 2005 |
Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Drug Therapy, Combination; Glutathione Peroxidase; Guanidines; Male; Malondialdehyde; Nitric Oxide; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioglycolates; Thiophenes; Tyrosine | 2004 |
Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney.
Topics: Animals; Benzyl Compounds; Biomarkers; Caspase 3; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Hydrocarbons, Fluorinated; Immunohistochemistry; In Vitro Techniques; Intercellular Adhesion Molecule-1; Kidney; Kidney Function Tests; Male; Malondialdehyde; Myocardium; Nitric Oxide; Oligopeptides; Organ Size; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Serpins; Tyrosine; Viral Proteins | 2004 |
Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Degranulation; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Leukotriene D4; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Parasympatholytics; Peroxidase; Phosphodiesterase Inhibitors; Quinolines; Radioligand Assay; Rats; Receptors, Leukotriene; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport.
Topics: Amino Acid Sequence; Animals; Antioxidants; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Chlorine; Cholesterol; Cricetinae; Electron Spin Resonance Spectroscopy; Humans; Hydrogen Peroxide; Hydrophobic and Hydrophilic Interactions; Nitrates; Nitrogen; Oxidation-Reduction; Peptides; Peroxidase; Peroxynitrous Acid; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2005 |
Immunogenicity of a brominated protein and successive establishment of a monoclonal antibody to dihalogenated tyrosine.
Topics: Animals; Antibodies, Monoclonal; Bromosuccinimide; Chromatography, Liquid; Diiodotyrosine; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Immunoglobulin M; Injections, Intraperitoneal; Lipopolysaccharides; Mass Spectrometry; Mice; Mice, Inbred C57BL; Peroxidase; Serum Albumin, Bovine; Tyrosine | 2005 |
Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Biopsy; Bleomycin; Epoxy Compounds; Immunoenzyme Techniques; Instillation, Drug; Male; Mice; Nitric Oxide Synthase; Peroxidase; Poly(ADP-ribose) Polymerases; Prostaglandin D2; Pulmonary Fibrosis; Random Allocation; Rosiglitazone; Thiazolidinediones; Tyrosine; Weight Loss | 2005 |
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS.
Topics: Animals; Brain; Brain Injuries; Electron Spin Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Tyrosine | 2005 |
Rho-kinase (ROCK-1 and ROCK-2) upregulation in oleic acid-induced lung injury and its restoration by Y-27632.
Topics: Amides; Animals; Blotting, Western; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Injections, Intravenous; Intracellular Signaling Peptides and Proteins; Lung; Male; Malondialdehyde; Nitrates; Nitrites; Oleic Acid; Peroxidase; Protein Serine-Threonine Kinases; Pyridines; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Tyrosine; Up-Regulation | 2005 |
Glycyrrhizae Radix attenuates peroxynitrite-induced renal oxidative damage through inhibition of protein nitration.
Topics: Animals; Blood Urea Nitrogen; Chromium; Free Radical Scavengers; Glycyrrhiza; Kidney; Male; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Plant Extracts; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine | 2005 |
Protective mechanisms of a metalloporphyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Catalysis; Cyclosporine; Gene Expression; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Malondialdehyde; Metalloporphyrins; Myocardium; Neutrophils; Peroxidase; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred Lew; Rats, Wistar; Tyrosine | 2005 |
Aging effect on myeloperoxidase in rat kidney and its modulation by calorie restriction.
Topics: Aging; Animals; Caloric Restriction; Diet; Energy Intake; Inflammation; Kidney; Lipopolysaccharides; Male; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Inbred F344; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2005 |
Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation.
Topics: Amino Acid Sequence; Animals; Biotin; Blood Platelets; Blotting, Western; Cell Communication; Cell Line; Cloning, Molecular; COS Cells; Cross-Linking Reagents; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Epidermal Growth Factor; Eptifibatide; Flow Cytometry; Humans; Immunoprecipitation; Mass Spectrometry; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Peptides; Peroxidase; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Threonine; Tissue Distribution; Transfection; Tyrosine | 2005 |
Caffeic acid phenethyl ester (CAPE) supplemented St. Thomas' hospital cardioplegic solution improves the antioxidant defense system of rat myocardium during ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Caffeic Acids; Cardioplegic Solutions; Catalase; Free Radical Scavengers; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Reperfusion Injury; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tyrosine | 2005 |
Nitration of the tyrosyl radical in ribonucleotide reductase by nitrogen dioxide: a gamma radiolysis study.
Topics: Catalysis; Dose-Response Relationship, Radiation; Electrons; Escherichia coli; Free Radicals; Gamma Rays; Models, Chemical; Models, Statistical; Nitric Oxide; Nitrogen; Nitrogen Dioxide; Oxygen; Peroxidase; Plasmids; Ribonucleotide Reductases; Time Factors; Tyrosine | 2005 |
Thalidomide treatment reduces colon injury induced by experimental colitis.
Topics: Animals; Colitis; Colon; Cytokines; Disease Models, Animal; Immunohistochemistry; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Interleukin-1; Mice; Neutrophils; Peroxidase; Poly Adenosine Diphosphate Ribose; Thalidomide; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Endothelial Growth Factor A | 2005 |
Time course and site(s) of cytochrome c tyrosine nitration by peroxynitrite.
Topics: Amino Acid Sequence; Animals; Cytochromes c; Electron Transport; Horses; Mitochondria, Heart; Molecular Sequence Data; Peroxidase; Peroxynitrous Acid; Potassium Cyanide; Rats; Sodium Cyanide; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetranitromethane; Time Factors; Tyrosine | 2005 |
Involvement of phospholipid, biomembrane integrity, and NO peroxidase activity in the NO catabolism by cytochrome c oxidase.
Topics: Animals; Cattle; Electron Transport Complex IV; Free Radicals; Hydrogen Peroxide; Intracellular Membranes; Mitochondria; Nitric Oxide; Oxidation-Reduction; Peroxidase; Phospholipids; Polarography; Spectrophotometry, Ultraviolet; Submitochondrial Particles; Tyrosine | 2005 |
Protective effect of trapidil against oxidative organ damage in burn injury.
Topics: Animals; Burns; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Protective Agents; Random Allocation; Rats; Rats, Wistar; Trapidil; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Animals; Brain; Corpus Striatum; Dopamine; Drug Evaluation, Preclinical; Enzyme Induction; Humans; Huntington Disease; Hypochlorous Acid; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2005 |
Role of sulfated tyrosines of thyroglobulin in thyroid hormonosynthesis.
Topics: Animals; Cells, Cultured; Iodine; Lactoperoxidase; Peptide Fragments; Peroxidase; Sulfates; Swine; Thyroglobulin; Thyroid Hormones; Tyrosine | 2005 |
Green tea polyphenol extract attenuates colon injury induced by experimental colitis.
Topics: Animals; Benzenesulfonates; Chromatography, High Pressure Liquid; Colitis; Colon; Flavonoids; Heme Oxygenase (Decyclizing); Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Peroxidase; Phenols; Phytotherapy; Plant Leaves; Polyphenols; Rats; Rats, Sprague-Dawley; Tea; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities.
Topics: Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Humans; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Point Mutation; Tryptophan; Tyrosine | 2005 |
Nitric oxide inhalation inhibits inducible nitric oxide synthase but not nitrotyrosine formation and cell apoptosis in rat lungs with meconium-induced injury.
Topics: Administration, Inhalation; Animals; Apoptosis; Interleukin-1; Lung; Male; Malondialdehyde; Meconium; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Tyrosine | 2005 |
Effects of Hypericum perforatum extract in a rat model of ischemia and reperfusion injury.
Topics: Animals; Antioxidants; Blood Pressure; Cytokines; Densitometry; Flavonoids; Hydroxybenzoates; Hypericum; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Neutrophils; P-Selectin; Peroxidase; Phenols; Phytotherapy; Plant Extracts; Poly(ADP-ribose) Polymerases; Polyphenols; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Shock; Time Factors; Treatment Outcome; Tyrosine | 2005 |
Inflammatory leukocytes and iron turnover in experimental hemorrhagic lung trauma.
Topics: Animals; Antigens, CD; Blast Injuries; Cadherins; Cell Movement; Endothelial Cells; Epithelial Cells; Heme Oxygenase-1; Hemoglobins; Hemorrhage; Inflammation; Iron; Leukocytes; Male; Oxidative Stress; Peroxidase; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Superoxide Dismutase; Superoxide Dismutase-1; Transferrin; Tyrosine | 2006 |
Intramolecular electron transfer between tyrosyl radical and cysteine residue inhibits tyrosine nitration and induces thiyl radical formation in model peptides treated with myeloperoxidase, H2O2, and NO2-: EPR SPIN trapping studies.
Topics: Cyclic N-Oxides; Cysteine; Dimerization; Disulfides; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Hydrogen Peroxide; Mass Spectrometry; Nitrites; Oxidation-Reduction; Peptides; Peroxidase; Spin Labels; Tyrosine | 2005 |
Effects of peroxidase and hydrogen peroxide on the dityrosine formation and the mixing characteristics of wheat-flour dough.
Topics: Bread; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Linking Reagents; Flour; Hydrogen Peroxide; Mass Spectrometry; Peroxidase; Tyrosine | 2005 |
Increased oxidative-related mechanisms in the spinal cord injury in old rats.
Topics: Age Factors; Analysis of Variance; Animals; Disease Models, Animal; Immunohistochemistry; Laminectomy; Male; Oxidation-Reduction; Peroxidase; Poly Adenosine Diphosphate Ribose; Rats; Spinal Cord Injuries; Time Factors; Tyrosine | 2006 |
Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease.
Topics: Aged; Bronchi; Bronchitis; Case-Control Studies; Cell Count; Epithelium; Female; Forced Expiratory Volume; Humans; Immunohistochemistry; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Pulmonary Disease, Chronic Obstructive; Reactive Nitrogen Species; Respiratory Mucosa; Smoking; Tyrosine; Vital Capacity; Xanthine Oxidase | 2005 |
NAD(P)H oxidase contributes to the progression of remote hepatic parenchymal injury and endothelial dysfunction, but not microvascular perfusion deficits.
Topics: Animals; Disease Progression; Endothelium; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Microcirculation; Models, Biological; NADPH Oxidases; Neutrophils; Oxidative Stress; Peroxidase; Reperfusion Injury; Tyrosine; Xanthine Oxidase | 2006 |
Calcineurin regulates myocardial function during acute endotoxemia.
Topics: Animals; Calcineurin Inhibitors; Cats; Cyclosporine; Endotoxemia; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocardium; Nitric Oxide Synthase Type II; Peroxidase; Protein Carbonylation; Superoxide Dismutase; Tacrolimus; Tyrosine | 2006 |
Modification of amino acid residues in human serum albumin by myeloperoxidase.
Topics: Bromides; Chlorides; Humans; Hydrogen Peroxide; Methionine; Neutrophils; Nitrites; Oxidation-Reduction; Oxygen; Peroxidase; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Tyrosine | 2006 |
Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Foam Cells; Humans; Lysine; Methionine; Methionine Sulfoxide Reductases; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Peroxidase; Protein Binding; Tyrosine | 2006 |
Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD.
Topics: Aged; Aldehydes; Biomarkers; Breath Tests; Female; Humans; Immunohistochemistry; Lactoferrin; Male; Middle Aged; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Smoking; Sputum; Tyrosine | 2006 |
The effects of chronic exposure to ethanol and cigarette smoke on the formation of peroxynitrite, level of nitric oxide, xanthine oxidase and myeloperoxidase activities in rat kidney.
Topics: Animals; Epithelial Cells; Ethanol; Immunohistochemistry; Inhalation Exposure; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Leukocytes, Mononuclear; Male; Nitric Oxide; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Smoking; Tyrosine; Xanthine Oxidase | 2006 |
Gastric expression of inducible nitric oxide synthase and myeloperoxidase in relation to nitrotyrosine in Helicobacter pylori-infected Mongolian gerbils.
Topics: Animals; Blotting, Western; Disease Models, Animal; Gastric Mucosa; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Nitric Oxide Synthase Type II; Peroxidase; Pyloric Antrum; Pylorus; Rats; Severity of Illness Index; Tyrosine | 2006 |
Effects of trapidil on renal ischemia-reperfusion injury.
Topics: Animals; Kidney; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Trapidil; Tumor Necrosis Factor-alpha; Tyrosine; Vasodilator Agents | 2006 |
Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite.
Topics: Animals; Atherosclerosis; Cells, Cultured; Endothelium, Vascular; Female; Humans; Hypochlorous Acid; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidants; Oxygen; Peroxidase; Peroxynitrous Acid; Phosphoproteins; Superoxides; Tyrosine; Uncoupling Agents | 2006 |
Neutrophils-derived peroxynitrite contributes to acute hyperalgesia and cell influx in zymosan arthritis.
Topics: Acute Disease; Animals; Arthritis, Experimental; Hindlimb; Hyperalgesia; Injections, Intra-Articular; Knee Joint; Male; Neutrophils; Nitric Oxide; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Synovial Fluid; Tyrosine; Uric Acid; Zymosan | 2007 |
Nitric oxide production in the ventilatory muscles in response to acute resistive loading.
Topics: Airway Resistance; Animals; Cytoplasmic Dyneins; Diaphragm; Dyneins; Endothelins; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Tyrosine | 2007 |
Establishment of a sandwich ELISA using commercial antibody for plasma or serum 3-nitrotyrosine (3NT). Elevation in inflammatory diseases and complementary between 3NT and myeloperoxidase.
Topics: Animals; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Mice; Peroxidase; Reagent Kits, Diagnostic; Reference Values; Tyrosine | 2007 |
The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug?
Topics: Anthracenes; Antidepressive Agents; Antioxidants; Atherosclerosis; Bridged Bicyclo Compounds; Cells, Cultured; Chromatography, High Pressure Liquid; Circular Dichroism; Depression; Drug Evaluation, Preclinical; Endothelial Cells; Humans; Hypericum; Lipoproteins, LDL; Malondialdehyde; Mass Spectrometry; Molecular Structure; Nonprescription Drugs; Oxidation-Reduction; Peroxidase; Perylene; Phloroglucinol; Phytotherapy; Protein Binding; Structure-Activity Relationship; Terpenes; Thiobarbituric Acid Reactive Substances; Thromboplastin; Tyrosine; Umbilical Veins | 2007 |
HTHP: a novel class of hexameric, tyrosine-coordinated heme proteins.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalase; Enzyme Stability; Heme-Binding Proteins; Hemeproteins; Models, Molecular; Molecular Sequence Data; Peroxidase; Protein Conformation; Rhodobacteraceae; Tyrosine | 2007 |
Efficiency of lornoxicam in lung and trachea injury caused by peroxynitrite.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Female; Lung; Male; Malondialdehyde; Peroxidase; Peroxynitrous Acid; Piroxicam; Rats; Respiratory Distress Syndrome; Trachea; Tracheal Diseases; Tyrosine | 2008 |
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Neurotransmitter Agents; New Zealand; Peroxidase; Prognosis; Proportional Hazards Models; Protein Carbonylation; Radionuclide Imaging; Retrospective Studies; Sex Factors; Stroke Volume; Tyrosine; Ventricular Dysfunction, Left | 2007 |
Beneficial synergistic effects of concurrent treatment with cilostazol and probucol against focal cerebral ischemic injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Brain Ischemia; Caspase 3; Cerebral Infarction; Chemotaxis, Leukocyte; Cilostazol; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Peroxidase; Poly(ADP-ribose) Polymerases; Probucol; Rats; Rats, Sprague-Dawley; Superoxides; Telencephalon; Tetrazoles; Treatment Outcome; Tyrosine | 2007 |
Pathways for intracellular generation of oxidants and tyrosine nitration by a macrophage cell line.
Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Probes; Nitric Oxide Synthase Type II; Nitrites; Nitrogen; Oxidants; Oxygen Consumption; Peroxidase; Superoxides; Time Factors; Tyrosine | 2007 |
Beneficial effects of FeTSPP, a peroxynitrite decomposition catalyst, in a mouse model of spinal cord injury.
Topics: Animals; Catalysis; Disease Models, Animal; DNA; I-kappa B Proteins; Interleukin-1beta; Interleukin-2; Lipid Peroxidation; Male; Metalloporphyrins; Mice; Mitochondria; Neutrophil Infiltration; NF-kappa B; Peroxidase; Peroxynitrous Acid; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Transport; Proto-Oncogene Proteins c-bcl-2; RNA; Spinal Cord Injuries; T-Lymphocytes; Tumor Necrosis Factor-alpha; Tyrosine | 2007 |
Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice.
Topics: Animals; Antimetabolites; Apoptosis; bcl-2-Associated X Protein; Buthionine Sulfoximine; DNA; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Mice; Neutrophil Infiltration; Peroxidase; Poly Adenosine Diphosphate Ribose; RNA; Spinal Cord Compression; Spinal Cord Injuries; Tyrosine | 2007 |
The metabolism and dechlorination of chlorotyrosine in vivo.
Topics: Albumins; Animals; Catalysis; Chlorine; Gas Chromatography-Mass Spectrometry; Hypochlorous Acid; Inflammation; Male; Monocytes; Mutation; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; Tyrosine | 2007 |
Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma.
Topics: Animals; Apoptosis; Base Sequence; bcl-2-Associated X Protein; Chemokines; Cyclooxygenase 2; Cytokines; DNA Primers; Estradiol; Male; Mice; Motor Activity; Neutrophils; Nitric Oxide Synthase Type II; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spinal Cord Injuries; Tyrosine | 2008 |
Inhibitory effect of curcuminoids and tetrahydrocurcuminoids on equine activated neutrophils and myeloperoxidase activity.
Topics: Animals; Benzothiazoles; Cell Separation; Cell Survival; Chlorides; Curcumin; Flavonoids; Horses; Immunohistochemistry; In Vitro Techniques; Luminescence; Neutrophil Activation; Nitrates; Oxidation-Reduction; Peroxidase; Phenols; Polyphenols; Reactive Oxygen Species; Sulfonic Acids; Taurine; Tyrosine | 2008 |
Combination of dexamethasone and etanercept reduces secondary damage in experimental spinal cord trauma.
Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Etanercept; Immunoglobulin G; In Situ Nick-End Labeling; Interleukin-1beta; Laminectomy; Male; Mice; Neutrophils; Nitric Oxide Synthase Type II; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Tyrosine | 2007 |
How DMSO, a widely used solvent, affects spinal cord injury.
Topics: Animals; Aorta, Abdominal; Dimethyl Sulfoxide; Disease Models, Animal; Free Radical Scavengers; Ligation; Malondialdehyde; Neuroprotective Agents; Nitrates; Nitrites; Peroxidase; Rabbits; Reperfusion Injury; Solvents; Spinal Cord; Spinal Cord Ischemia; Time Factors; Tyrosine | 2008 |
The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans.
Topics: Adult; Case-Control Studies; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Isoprostanes; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Oxidative Stress; Peroxidase; Superoxide Dismutase; Tyrosine | 2008 |
Enzymatic elimination of hydrogen peroxide by a methemoglobin/L-Tyrosine system.
Topics: Hemoglobins; Hydrogen Peroxide; Methemoglobin; Oxidation-Reduction; Peroxidase; Temperature; Tyrosine | 2007 |
H2O2/nitrite-induced post-translational modifications of human hemoglobin determined by mass spectrometry: redox regulation of tyrosine nitration and 3-nitrotyrosine reduction by antioxidants.
Topics: Amino Acid Sequence; Antioxidants; Ascorbic Acid; Cysteine; Hemin; Hemoglobins; Humans; Hydrogen Peroxide; Methionine; Molecular Sequence Data; Nitrates; Nitrites; Oxidation-Reduction; Peroxidase; Protein Processing, Post-Translational; Reactive Nitrogen Species; Spectrometry, Mass, Electrospray Ionization; Trypsin; Tyrosine; Vitamin B 12 | 2008 |
Methotrexate-induced nitrosative stress may play a critical role in small intestinal damage in the rat.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Duodenum; Ileum; Immunohistochemistry; Injections, Intraperitoneal; Intestine, Small; Jejunum; Male; Methotrexate; Neutrophil Infiltration; Neutrophils; Nitrites; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reactive Nitrogen Species; Time Factors; Tyrosine | 2008 |
Nitration of respiratory epithelial cells by myeloperoxidase depends on extracellular nitrite.
Topics: Blotting, Western; Cell Line, Tumor; Coculture Techniques; Epithelial Cells; Extracellular Space; Glutathione; Humans; Hydrogen Peroxide; Immunochemistry; Neutrophils; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Peroxidase; Respiratory Mucosa; Tyrosine | 2008 |
Elevated levels of myeloperoxidase, white blood cell count and 3-chlorotyrosine in Taiwanese patients with acute myocardial infarction.
Topics: Acute Disease; Aged; Biomarkers; Female; Humans; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Peroxidase; Sensitivity and Specificity; Taiwan; Tyrosine | 2008 |
Loss of 3-chlorotyrosine by inflammatory oxidants: implications for the use of 3-chlorotyrosine as a bio-marker in vivo.
Topics: Animals; Biomarkers; HL-60 Cells; Humans; Hypochlorous Acid; Inflammation; Macrophage Activation; Macrophages; Mice; Neutrophils; Nitrites; Oxidants; Peroxidase; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine | 2008 |
Differential contribution of neutrophilic granulocytes and macrophages to nitrosative stress in a host-parasite animal model.
Topics: Animals; B-Lymphocytes; Carps; Cell Death; Gene Expression Regulation, Enzymologic; Host-Parasite Interactions; Macrophages; Melarsoprol; Models, Animal; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Parasitemia; Parasites; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Spleen; Stress, Physiological; Trypanosoma; Trypanosomiasis; Tyrosine | 2008 |
p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
Topics: Abdomen; Animals; Calmodulin; Cardiotonic Agents; Caveolin 1; Chemokine CXCL1; Chemokine CXCL2; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Estradiol; Heart Diseases; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Mitogen-Activated Protein Kinase 11; Myocardium; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peroxidase; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation; Ventricular Function | 2008 |
Augmented inducible nitric oxide synthase expression and increased NO production reduce sepsis-induced lung injury and mortality in myeloperoxidase-null mice.
Topics: Animals; Escherichia coli; Escherichia coli Infections; Gene Expression Regulation, Enzymologic; Lung; Lung Injury; Mice; Mice, Knockout; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidants; Peroxidase; Pulmonary Edema; Sepsis; Tyrosine | 2008 |
Inhibition of myeloperoxidase-mediated protein nitration by tempol: Kinetics, mechanism, and implications.
Topics: Antioxidants; Catalysis; Cyclic N-Oxides; Humans; Kinetics; Nitrates; Peroxidase; Protein Processing, Post-Translational; Reactive Oxygen Species; Ribonucleases; Spin Labels; Tyrosine | 2008 |
Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis.
Topics: Androgen Antagonists; Animals; Apoptosis; Blotting, Western; Cell Separation; Chemokines; Cytokines; DNA Fragmentation; Flutamide; Glutathione Transferase; Hemorrhage; Hepatitis; Hepatocytes; Hypoxia-Inducible Factor 1, alpha Subunit; Kupffer Cells; Liver; Male; Mice; Mice, Inbred C3H; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Tyrosine | 2008 |
Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Glucose; Body Weight; Deoxyguanosine; Disease Models, Animal; Inflammation; Insulin; Lipids; Lipoproteins, LDL; Metabolic Syndrome; Oxidative Stress; Peroxidase; Rats; Rats, Inbred SHR; Tyrosine; Ubiquinone | 2008 |
Reduced brain injury in CD18-deficient mice after experimental intracerebral hemorrhage.
Topics: Animals; Brain Edema; CD18 Antigens; Cerebral Hemorrhage; Immunohistochemistry; Male; Mice; Mice, Knockout; Peroxidase; Reperfusion Injury; Tyrosine | 2008 |
Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Ischemia; Caspase 3; Caspase 9; Chromatography, High Pressure Liquid; Dapsone; Immunoblotting; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Neuroprotective Agents; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine | 2008 |
Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites.
Topics: Administration, Oral; Animals; Antioxidants; Aorta; Atherosclerosis; Computer Simulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; HL-60 Cells; Humans; Macrophages; Peroxidase; Quantitative Structure-Activity Relationship; Quercetin; Rats; Rats, Inbred Strains; Tyrosine | 2008 |
Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.
Topics: Amidines; Animals; Benzylamines; Blood Pressure; Chemokines; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Fluid Therapy; Glutathione Transferase; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Adhesion Molecule-1; Isoenzymes; Liver; Liver Diseases; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peroxidase; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Tyrosine; Wounds and Injuries | 2008 |
Beneficial effects of ethyl pyruvate in a mouse model of spinal cord injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Fas Ligand Protein; Gene Expression Regulation; Humans; Inflammation; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Peroxidase; Phosphorylation; Pyruvates; Spinal Cord Injuries; Time Factors; Tyrosine | 2009 |
Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity.
Topics: Animals; Capillary Leak Syndrome; Capillary Permeability; Catalysis; Hemodynamics; Interleukin-2; Lung; Lymph; Malondialdehyde; Neoplasms; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Peroxynitrous Acid; Pulmonary Gas Exchange; Recombinant Proteins; Sheep; Tyrosine | 2008 |
Antithyroid drug carbimazole and its analogues: synthesis and inhibition of peroxidase-catalyzed iodination of L-tyrosine.
Topics: Antithyroid Agents; Carbimazole; Catalysis; Computer Simulation; Halogenation; Molecular Structure; Peroxidase; Structure-Activity Relationship; Tyrosine | 2008 |
Thiamine inhibits formation of dityrosine, a specific marker of oxidative injury, in reactions catalyzed by oxoferryl forms of hemoglobin.
Topics: Hemoglobins; Humans; Kinetics; Metmyoglobin; Oxidation-Reduction; Peroxidase; Thiamine; Tyrosine | 2008 |
Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure.
Topics: Cells, Cultured; Chronic Disease; Endothelial Cells; Gene Expression; Heart Failure; Humans; Hydrogen Peroxide; Immunohistochemistry; Myocardium; Oxidants; Oxidative Stress; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine; Umbilical Veins | 2009 |
Increased nitrotyrosine plasma levels in relation to systemic markers of inflammation and myeloperoxidase in chronic heart failure.
Topics: Aged; Biomarkers; Chronic Disease; Cohort Studies; Female; Heart Failure; Humans; Inflammation Mediators; Male; Middle Aged; Peroxidase; Tyrosine | 2009 |
The effect of neighboring methionine residue on tyrosine nitration and oxidation in peptides treated with MPO, H2O2, and NO2(-) or peroxynitrite and bicarbonate: role of intramolecular electron transfer mechanism?
Topics: Acetylation; Bicarbonates; Electron Spin Resonance Spectroscopy; Electron Transport; Hydrogen Peroxide; Kinetics; Methionine; Nitrates; Peptides; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Tyrosine | 2009 |
16,16-Dimethyl prostaglandin E2 efficacy on prevention and protection from bleomycin-induced lung injury and fibrosis.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Bleomycin; Body Weight; Bronchoalveolar Lavage Fluid; Collagen; Disease Models, Animal; Infusions, Subcutaneous; Interleukin-1beta; Lung; Lung Injury; Male; Mice; Peroxidase; Pneumonia; Protective Agents; Pulmonary Edema; Pulmonary Fibrosis; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2009 |
Oxidation and nitration of ribonuclease and lysozyme by peroxynitrite and myeloperoxidase.
Topics: Animals; Cattle; Chickens; Chromatography, High Pressure Liquid; Egg White; Free Radicals; Hydrogen Peroxide; Inflammation; Muramidase; Peroxidase; Peroxynitrous Acid; Pronase; Proteins; Ribonucleases; Spectrometry, Mass, Electrospray Ionization; Spleen; Tyrosine | 2009 |
Depot-specific alterations to insulin signaling in mesenteric adipose tissue during intestinal inflammatory response.
Topics: Adipose Tissue; Animals; Colitis; Insulin; Insulin Receptor Substrate Proteins; Intestinal Mucosa; Intestines; Male; Mesentery; Peroxidase; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Trinitrobenzenesulfonic Acid; Tyrosine | 2009 |
Lactobacillus fermentum CECT 5716 prevents and reverts intestinal damage on TNBS-induced colitis in mice.
Topics: Animals; Colitis; Colony Count, Microbial; Cytokines; Disease Models, Animal; Eicosanoids; Immunoenzyme Techniques; Intestinal Mucosa; Limosilactobacillus fermentum; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; Peroxidase; Probiotics; Trinitrobenzenesulfonic Acid; Tyrosine | 2009 |
Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage.
Topics: Actin Cytoskeleton; Animals; Avena; Colon; Colonic Diseases; Cytoskeleton; Edible Grain; Ethanol; Intestinal Mucosa; Male; Models, Biological; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Permeability; Peroxidase; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Tight Junctions; Tyrosine | 2009 |
Erythropoietin attenuates lung injury in lipopolysaccharide treated rats.
Topics: Animals; Erythropoietin; Lipopolysaccharides; Lung; Lung Injury; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Rats; Rats, Sprague-Dawley; Tyrosine | 2009 |
Reactive oxygen species mediate liver injury through parenchymal nuclear factor-kappaB inactivation in prolonged ischemia/reperfusion.
Topics: Animals; Apoptosis; Blotting, Western; Cell Nucleus; Glutathione; Hepatocytes; I-kappa B Proteins; Interleukin-1beta; Kupffer Cells; Lipid Peroxidation; Liver Diseases; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Peroxidase; Phosphorylation; Protein Transport; Reactive Oxygen Species; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine | 2009 |
Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cytokines; Disease Models, Animal; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Mice; Motor Activity; Neutrophil Infiltration; NF-kappa B; Peroxidase; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Spinal Cord Injuries; Thiobarbituric Acid Reactive Substances; Tyrosine | 2009 |
Thalidomide suppresses sclerosing encapsulating peritonitis in a rat experimental model.
Topics: Animals; Anti-Infective Agents; Blotting, Western; Chlorhexidine; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; I-kappa B Proteins; Immunohistochemistry; Immunosuppressive Agents; NF-kappa B; Nitric Oxide Synthase Type II; Peritonitis; Peroxidase; Poly Adenosine Diphosphate Ribose; Rats; Thalidomide; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Endothelial Growth Factor A | 2009 |
Oxidative damage markers and antioxidants in patients with acute myocardial infarction and their clinical significance.
Topics: Antioxidants; Humans; Inflammation; Myocardial Infarction; Oxidative Stress; Peroxidase; Tyrosine | 2008 |
Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats.
Topics: Actins; Air; Animals; Animals, Newborn; Blood Gas Analysis; Blood Vessels; Carbon Dioxide; Elastin; Fluorescent Antibody Technique; Heart Rate; Hypercapnia; Lung; Lung Injury; Neutrophils; Organ Size; Peroxidase; Rats; Subcellular Fractions; Tyrosine; von Willebrand Factor | 2009 |
Role of neutrophils in arginine-asymmetric dimethylarginine pathway subsequent to endotoxemia.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Guinea Pigs; Lipopolysaccharides; Liver; Male; Neutrophils; Peroxidase; Tyrosine | 2009 |
Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma.
Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Cytokines; Disease Models, Animal; Fas Ligand Protein; Hydrocarbons, Fluorinated; In Situ Nick-End Labeling; Laminectomy; Lipid Peroxidation; Liver X Receptors; Male; Mice; Movement Disorders; Myelitis; Neutrophil Infiltration; NF-kappa B; Nitric Oxide Synthase Type II; Orphan Nuclear Receptors; Peroxidase; Poly Adenosine Diphosphate Ribose; Proteins; Proto-Oncogene Proteins c-bcl-2; Spinal Cord Injuries; Statistics, Nonparametric; Sulfonamides; Time Factors; Tyrosine | 2010 |
Adenosine A2A receptor-selective stimulation reduces signaling pathways involved in the development of intestine ischemia and reperfusion injury.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Fas Ligand Protein; Intercellular Adhesion Molecule-1; Intestine, Small; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; P-Selectin; Peroxidase; Phenethylamines; Poly Adenosine Diphosphate Ribose; Proto-Oncogene Proteins c-bcl-2; Receptor, Adenosine A2A; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Molecular biological effects of selective neuronal nitric oxide synthase inhibition in ovine lung injury.
Topics: Airway Obstruction; Animals; Cell Nucleus; Enzyme Activation; Hemodynamics; Indazoles; Interleukin-8; Lung Injury; Malondialdehyde; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Peroxidase; Poly(ADP-ribose) Polymerases; Pressure; Regional Blood Flow; Respiratory Function Tests; Sheep; Survival Analysis; Trachea; Transcription Factor RelA; Tyrosine | 2010 |
Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity.
Topics: Animals; Electron Spin Resonance Spectroscopy; Gadolinium; Kinetics; Magnetic Resonance Imaging; Mice; NIH 3T3 Cells; Organometallic Compounds; Oxidation-Reduction; Peroxidase; Proteins; Tyrosine | 2010 |
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cannabinoids; Caspases; Cisplatin; In Situ Nick-End Labeling; Inflammation; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Peroxidase; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Receptor, Cannabinoid, CB2; Tyrosine | 2010 |
Chemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antibodies, Monoclonal; Chromatography, Liquid; Deoxyguanosine; Female; Halogens; Inflammation; Lipopolysaccharides; Liver; Mass Spectrometry; Mice; Mice, Inbred C57BL; Peroxidase; Rats; Rats, Wistar; Time Factors; Tyrosine | 2010 |
Differing effects of exogenous and endogenous hydrogen sulphide in carrageenan-induced knee joint synovitis in the rat.
Topics: Animals; Carrageenan; Hydrogen Sulfide; Knee Joint; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Wistar; Synovitis; Tyrosine | 2010 |
Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury.
Topics: Animals; Apoptosis; Cytokines; Enzyme Induction; Fas Ligand Protein; Male; Mice; Neutrophil Infiltration; Nitric Oxide Synthase; Peroxidase; PPAR delta; PPAR-beta; Spinal Cord Injuries; Sulfones; Thiazoles; Thiophenes; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
A peroxidase/dual oxidase system modulates midgut epithelial immunity in Anopheles gambiae.
Topics: Animals; Anopheles; Anti-Bacterial Agents; Bacteria; Bacterial Physiological Phenomena; Blood; Digestive System; Enzyme Induction; Epithelial Cells; Extracellular Matrix; Female; Gene Expression Regulation; Insect Proteins; Models, Biological; NADPH Oxidases; Nitric Oxide Synthase; Permeability; Peroxidase; Plasmodium berghei; Plasmodium falciparum; RNA Interference; Tyrosine | 2010 |
Suppression of allergen-induced respiratory dysfunction and airway inflammation in sensitized guinea pigs by Mn(II)(Me(2)DO2A), a novel superoxide scavenger compound.
Topics: Allergens; Anaphylaxis; Animals; Anti-Asthmatic Agents; Apoptosis; Asthma; Bronchoconstriction; Caspase 3; Free Radical Scavengers; Guinea Pigs; Male; Mast Cells; Organometallic Compounds; Ovalbumin; Peroxidase; Superoxides; Thiobarbituric Acid Reactive Substances; Tyrosine | 2010 |
Inhaled nitric oxide prevents 3-nitrotyrosine formation in the lungs of neonatal mice exposed to >95% oxygen.
Topics: Animals; Chemokine CCL2; Hyperoxia; Intercellular Adhesion Molecule-1; Lung; Lung Injury; Mice; Nitric Oxide; Oxygen; Peroxidase; Tyrosine | 2010 |
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Heart Atria; Humans; Lymphocyte Activation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neutrophils; Peroxidase; Tyrosine | 2010 |
Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis.
Topics: Adolescent; Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blister; Female; Humans; Hypochlorous Acid; Keratinocytes; Lewis X Antigen; Macrophages; Male; Middle Aged; Peroxidase; Stevens-Johnson Syndrome; Tyrosine | 2010 |
Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients.
Topics: Aged; Atherosclerosis; Carotid Arteries; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Intramolecular Oxidoreductases; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Tyrosine | 2010 |
ApoA-1 mimetic peptide reverses uremia-induced upregulation of pro-atherogenic pathways in the aorta.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Thoracic; Apolipoprotein A-I; Arachidonate 12-Lipoxygenase; Arteritis; Atherosclerosis; Chemokine CCL2; Cyclooxygenase 2; Male; NADPH Oxidases; NF-kappaB-Inducing Kinase; Nitric Oxide Synthase Type II; Oxidative Stress; Peptides; Peroxidase; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Tyrosine; Up-Regulation; Uremia | 2010 |
Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.
Topics: Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Cystic Fibrosis; Disease Progression; Female; Humans; Infant; Inflammation; Male; Neutrophils; Oxidation-Reduction; Peroxidase; Pseudomonas aeruginosa; Respiratory Tract Infections; Tyrosine | 2010 |
Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve.
Topics: Animals; Apoptosis; Brain Ischemia; Ghrelin; Humans; Immunohistochemistry; Inflammation; Interleukin-6; Male; Matrix Metalloproteinase 9; Neutrophils; Nitric Oxide Synthase Type I; Peroxidase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Tyrosine; Vagotomy; Vagus Nerve | 2011 |
[The functional properties and oxidative modification of plasma and neutrophil proteins in community-acquired pneumonia].
Topics: Adolescent; Adult; Community-Acquired Infections; Female; Humans; Hydroxyl Radical; Lung; Male; Middle Aged; Neutrophils; Oxidation-Reduction; Oxidative Stress; Peroxidase; Plasma; Pneumonia; Protein Carbonylation; Tryptophan; Tyrosine; Young Adult | 2010 |
Prevention of bleomycin-induced pulmonary fibrosis by a novel antifibrotic peptide with relaxin-like activity.
Topics: Animals; Bleomycin; Bronchi; Cell Line, Tumor; Collagen; Cyclic AMP; Cyclic GMP; Fibroblasts; Goblet Cells; Humans; Lung; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Monocytes; Muscle, Smooth; Nitric Oxide; Peptides; Peroxidase; Pulmonary Fibrosis; Receptors, G-Protein-Coupled; Receptors, Peptide; Relaxin; Signal Transduction; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1; Tyrosine | 2010 |
Local and cardiorenal effects of periodontitis in nitric oxide-deficient hypertensive rats.
Topics: Alveolar Bone Loss; Animals; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Heart; Hypertension; Kidney; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Periodontitis; Peroxidase; Radiography; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tyrosine | 2011 |
Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzamides; Bridged Bicyclo Compounds; Gene Expression Regulation, Enzymologic; Indomethacin; Intestine, Small; Macrophages; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nitric Oxide Synthase Type II; Peroxidase; Receptors, Nicotinic; RNA, Messenger; Tyrosine; Ulcer | 2011 |
Evaluation of oxidative and nitrosative stress in hemodialysis patients.
Topics: Antioxidants; Biomarkers; Body Mass Index; Case-Control Studies; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Peroxidase; Renal Dialysis; Tyrosine | 2010 |
Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury.
Topics: Animals; Burns; Capillary Permeability; Catalysis; Disease Models, Animal; Female; Hemodynamics; Interleukin-8; Lung; Metalloporphyrins; Peroxidase; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Pulmonary Circulation; Sheep; Smoke Inhalation Injury; Tyrosine; Vascular Endothelial Growth Factor A | 2011 |
Identification of the peroxidase-generated intermolecular dityrosine cross-link in bovine α-lactalbumin.
Topics: Animals; Cattle; Cross-Linking Reagents; Lactalbumin; Oxidation-Reduction; Peroxidase; Protein Conformation; Tyrosine | 2011 |
3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation.
Topics: Aged; Biomarkers; Cell Survival; Female; Humans; Male; Mass Spectrometry; Middle Aged; Neutrophils; Peroxidase; Pulmonary Disease, Chronic Obstructive; Sputum; Tyrosine | 2010 |
Protein carbamylation renders high-density lipoprotein dysfunctional.
Topics: Adult; Aged; Apolipoprotein A-I; Atherosclerosis; CD36 Antigens; Cells, Cultured; Cholesterol; Cyanates; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Mass Spectrometry; Middle Aged; Oxidation-Reduction; Peroxidase; Protein Processing, Post-Translational; Tyrosine | 2011 |
Mechanistic aspects of inducible nitric oxide synthase-induced lung injury in burn trauma.
Topics: Analysis of Variance; Animals; Burns; Disease Models, Animal; Female; Imidazoles; Immunohistochemistry; Interleukin-8; Lung; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Peroxidase; Piperazines; Pulmonary Gas Exchange; Pyrimidines; RNA, Messenger; Sheep; Smoke Inhalation Injury; Tyrosine | 2011 |
Natural almond skin reduced oxidative stress and inflammation in an experimental model of inflammatory bowel disease.
Topics: Animals; Colitis; Colon; fas Receptor; I-kappa B Proteins; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Interleukin-1beta; Lipid Peroxidation; Male; MAP Kinase Kinase 4; Mice; Neutrophil Infiltration; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Oxidative Stress; P-Selectin; Peroxidase; Phytotherapy; Plant Preparations; Poly(ADP-ribose) Polymerases; Prunus; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis.
Topics: Adrenomedullin; Animals; Anti-Inflammatory Agents; Bleomycin; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Inflammation Mediators; Injections, Intraperitoneal; Lung; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Peroxidase; Pneumonia; Poly(ADP-ribose) Polymerases; Pulmonary Fibrosis; Severity of Illness Index; Time Factors; Transforming Growth Factor beta; Tyrosine | 2011 |
Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes.
Topics: Alanine Transaminase; Aldehydes; Animals; Anti-Inflammatory Agents; Fatty Liver; Inflammation; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NADPH Oxidases; Nitric Oxide Synthase Type II; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peroxidase; Plant Extracts; Reactive Oxygen Species; Stress, Physiological; Tea; Tyrosine | 2012 |
Topography of tyrosine residues and their involvement in peroxidation of polyunsaturated cardiolipin in cytochrome c/cardiolipin peroxidase complexes.
Topics: Animals; Cardiolipins; Computer Simulation; Cytochromes c; Electron Spin Resonance Spectroscopy; Heme; Horses; Hydrogen Peroxide; Iron; Magnetic Resonance Spectroscopy; Mitochondrial Membranes; Mutation; Myocardium; Oxygen; Oxygenases; Peroxidase; Peroxidases; Phenylalanine; Tyrosine | 2011 |
Effects of oral administration of (L)-arginine, (L)-NAME and allopurinol on intestinal ischemia/reperfusion injury in rats.
Topics: Administration, Oral; Allopurinol; Animals; Arginine; Catalase; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tyrosine | 2011 |
Anti-inflammatory effect of the epigallocatechin gallate following spinal cord trauma in rat.
Topics: Animals; Anti-Inflammatory Agents; Catechin; Cyclooxygenase 2; Densitometry; Immunohistochemistry; Interleukin-1beta; Male; Myelin Sheath; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
CGS 21680, an agonist of the adenosine (A2A) receptor, decreases acute lung inflammation.
Topics: Acute Disease; Adenosine; Adenosine A2 Receptor Agonists; Animals; bcl-2-Associated X Protein; Carrageenan; Cytokines; Enzyme Activation; Fas Ligand Protein; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Mice; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide Synthase Type II; Nitrites; P-Selectin; Peroxidase; Phenethylamines; Pleurisy; Pneumonia; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptor, Adenosine A2A; Transcription Factor RelA; Tyrosine | 2011 |
Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima.
Topics: Biocatalysis; Cell Wall; Cross-Linking Reagents; Eimeria; Oocysts; Peroxidase; Protein Structure, Tertiary; Protozoan Proteins; Tyrosine | 2011 |
Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents.
Topics: Animals; Cell Death; Cell Proliferation; Enzyme Inhibitors; Guanidines; Immunohistochemistry; In Situ Nick-End Labeling; Injections, Intraperitoneal; Ki-67 Antigen; Male; Methotrexate; Mice; Mice, Knockout; Mucositis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Wistar; Tyrosine | 2011 |
Inhibition of peroxynitrite- and peroxidase-mediated protein tyrosine nitration by imidazole-based thiourea and selenourea derivatives.
Topics: Animals; Cattle; Crystallography, X-Ray; Imidazoles; Models, Molecular; Molecular Structure; Nitrates; Organoselenium Compounds; Peroxidase; Peroxynitrous Acid; Serum Albumin, Bovine; Stereoisomerism; Thiourea; Tyrosine; Urea | 2011 |
Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease.
Topics: Airway Remodeling; Animals; Dinoprost; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Guinea Pigs; Hypertension, Pulmonary; Inflammation; Lung; Oxidative Stress; Peroxidase; Pulmonary Disease, Chronic Obstructive; Purines; Smoking; Thiones; Thioxanthenes; Tyrosine | 2012 |
Hydrogen inhalation ameliorates lipopolysaccharide-induced acute lung injury in mice.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Bronchoalveolar Lavage Fluid; Caspase 3; Cytokines; Hydrogen; Lipopolysaccharides; Male; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Peroxidase; Pulmonary Edema; Superoxide Dismutase; Treatment Outcome; Tyrosine | 2011 |
Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis.
Topics: Animals; Blood Gas Analysis; Ceftazidime; Female; Hemodynamics; Humans; Lung; Male; Myocardium; Oxygen; Peroxidase; Protein C; Recombinant Proteins; Respiratory Distress Syndrome; Sepsis; Sheep; Treatment Outcome; Tyrosine | 2012 |
The free amino acid tyrosine enhances the chlorinating activity of human myeloperoxidase.
Topics: Antioxidants; Cells, Cultured; Halogenation; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; Microscopy, Fluorescence; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Sulfhydryl Compounds; Taurine; Tyrosine | 2012 |
Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions.
Topics: Apolipoprotein A-I; Atherosclerosis; Halogenation; Humans; Hypochlorous Acid; Lipoproteins, HDL; Nitrogen; Oxidation-Reduction; Oxidative Stress; Peroxidase; Protein Processing, Post-Translational; Tyrosine | 2012 |
Laccase- and peroxidase-free tyrosinase production by isolated microbial strain.
Topics: Cluster Analysis; Copper Sulfate; Culture Media; DNA, Bacterial; DNA, Ribosomal; Enzyme Activators; Hydrazones; Hydrogen-Ion Concentration; Laccase; Microscopy, Electron, Scanning; Molecular Sequence Data; Monophenol Monooxygenase; Peroxidase; Phylogeny; Ribotyping; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Soil Microbiology; Streptomyces antibioticus; Temperature; Tyrosine | 2012 |
Nitro-oxidative stress biomarkers in active and inactive men.
Topics: Adult; Age Factors; Biomarkers; Exercise; Humans; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Peroxidase; Sedentary Behavior; Tyrosine | 2012 |
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine.
Topics: Biomarkers; Blood Proteins; Case-Control Studies; Female; Humans; Male; Oxidants; Oxidation-Reduction; Peroxidase; Smoking; Sulfhydryl Compounds; Thiocyanates; Tyrosine | 2012 |
Desferrioxamine inhibits protein tyrosine nitration: mechanisms and implications.
Topics: Cell Membrane; Deferoxamine; Erythrocytes; Free Radical Scavengers; Humans; Lung; Nitrogen Dioxide; Oxidants, Photochemical; Peroxidase; Proteins; Siderophores; Tyrosine | 2012 |
N-methyl-D-aspartate receptor antagonist therapy suppresses colon motility and inflammatory activation six days after the onset of experimental colitis in rats.
Topics: Animals; Colitis; Colon; Disease Models, Animal; Gastrointestinal Motility; Hemodynamics; Interleukin-6; Kynurenic Acid; Male; Microcirculation; Nitric Oxide; Peroxidase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Xanthine Dehydrogenase | 2012 |
Bradykinin- and lipopolysaccharide-induced bradykinin B2 receptor expression, interleukin 8 release and "nitrosative stress" in bronchial epithelial cells BEAS-2B: role for neutrophils.
Topics: Bradykinin; Bronchi; Cell Line; Coculture Techniques; Epithelial Cells; Gene Expression Regulation; Humans; Interleukin-8; Lipopolysaccharides; Neutrophils; Peroxidase; Reactive Nitrogen Species; Receptor, Bradykinin B2; Tyrosine | 2012 |
[Characterization of the antiinflammatory properties of methane inhalation during ischaemia-reperfusion].
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Biomarkers; Carbon Dioxide; Disease Models, Animal; Dogs; Hemodynamics; Inflammation; Intestine, Small; Leukocytes; Methane; Peroxidase; Random Allocation; Reperfusion Injury; Superoxides; Tyrosine | 2012 |
Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis.
Topics: Aged; Aged, 80 and over; Animals; Blood Chemical Analysis; Blood Proteins; Chromatography, Liquid; Citrulline; Female; Humans; Hydrolysis; Lysine; Male; Microwaves; Middle Aged; Peroxidase; Renal Dialysis; Tandem Mass Spectrometry; Time Factors; Tyrosine | 2012 |
A plasma oxidative stress global index in early stages of chronic venous insufficiency.
Topics: Adult; Advanced Oxidation Protein Products; Biomarkers; Case-Control Studies; Catalase; Chronic Disease; Disease Progression; Early Diagnosis; Female; Glutathione; Humans; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Peroxidase; Predictive Value of Tests; Protein Carbonylation; Sulfhydryl Compounds; Tyrosine; Ultrasonography, Doppler, Color; Uric Acid; Veins; Venous Insufficiency; Xanthine Oxidase | 2013 |
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.
Topics: Adult; Aged; Apolipoprotein A-I; Arthritis, Rheumatoid; Cardiovascular Diseases; Case-Control Studies; Cholesterol; Female; Halogenation; Humans; Lipoproteins, HDL; Male; Middle Aged; Oxidation-Reduction; Peptide Mapping; Peroxidase; Tandem Mass Spectrometry; Tyrosine | 2013 |
The potentiation of myeloperoxidase activity by the glycosaminoglycan-dependent binding of myeloperoxidase to proteins of the extracellular matrix.
Topics: Cells, Cultured; Collagen Type IV; Dimerization; Endothelium, Vascular; Extracellular Matrix Proteins; Fibronectins; Glycosaminoglycans; Humans; Nitrates; Oxidative Stress; Peroxidase; Protein Binding; Tyrosine | 2013 |
The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: involvement of redox and inflammatory cascades.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cardiotonic Agents; Caspase 3; Cyclooxygenase 2; DNA Fragmentation; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Intercellular Adhesion Molecule-1; Lipoxygenase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-E2-Related Factor 2; NF-kappa B; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Triterpenes; Tumor Necrosis Factor-alpha; Tyrosine | 2013 |
Tyrosyl radicals in dehaloperoxidase: how nature deals with evolving an oxygen-binding globin to a biologically relevant peroxidase.
Topics: Adaptation, Physiological; Animals; Hemoglobins; Oxidation-Reduction; Oxygen; Peroxidase; Peroxidases; Polychaeta; Protein Binding; Tyrosine | 2013 |
Inhibition of inducible nitric oxide synthase-derived nitric oxide as a therapeutical target for acute pancreatitis induced by secretory phospholipase A2.
Topics: Animals; Enzyme Inhibitors; Hyperalgesia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Pain; Pancreas; Pancreatitis; Peroxidase; Phospholipases A2, Secretory; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tyrosine | 2014 |
Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats.
Topics: Amides; Animals; Catalase; Glutathione; Inflammation; Kidney; Male; Malondialdehyde; MAP Kinase Kinase 1; MAP Kinase Signaling System; Muscle, Skeletal; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Peroxynitrous Acid; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; rho-Associated Kinases; rhoA GTP-Binding Protein; Superoxide Dismutase; Tyrosine | 2014 |
Dietary fish oil reduces systemic inflammation and ameliorates sepsis-induced liver injury by up-regulating the peroxisome proliferator-activated receptor gamma-mediated pathway in septic mice.
Topics: Animals; Biomarkers; Fatty Acids, Omega-3; Fish Oils; Inflammation; Interleukin-10; Interleukin-6; Liver; Liver Diseases; Male; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Peroxidase; PPAR gamma; Sepsis; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2014 |
A dityrosine network mediated by dual oxidase and peroxidase influences the persistence of Lyme disease pathogens within the vector.
Topics: Animals; Arthropod Proteins; Arthropod Vectors; Borrelia burgdorferi; Gastrointestinal Tract; Gene Expression Regulation, Enzymologic; Humans; Ixodes; Lyme Disease; Mice; Mice, Inbred C3H; Microbial Viability; Microscopy, Confocal; NADPH Oxidases; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tyrosine | 2014 |
Tyrosine can protect against oxidative stress through ferryl hemoglobin reduction.
Topics: Antioxidants; Hemoglobins; Hep G2 Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Peroxidase; Phenylalanine; Serum Albumin; Tyrosine | 2014 |
Myeloperoxidase in cardiovascular disease.
Topics: Biomarkers; Case-Control Studies; Coronary Artery Disease; Free Radicals; Gene Expression; Heart Failure; Humans; Immunity, Innate; Peroxidase; Plaque, Atherosclerotic; Prognosis; Reactive Nitrogen Species; Reactive Oxygen Species; Survival Analysis; Tyrosine | 2013 |
Effect of MPO/H2O2/NO(-) system on nitric oxide-mediated modification of TTR amyloid and serum TTR in FAP ATTR Val30Met patients.
Topics: Adult; Amyloid; Amyloid Neuropathies, Familial; Female; Humans; Hydrogen Peroxide; Lipoproteins, HDL; Middle Aged; Mutation; Nitric Oxide; Peroxidase; Prealbumin; Tyrosine | 2014 |
Aging aggravates nitrate-mediated ROS/RNS changes.
Topics: Adult; Aged; Aging; Angina, Unstable; Animals; Aorta, Thoracic; Female; Glutathione; Humans; Isosorbide Dinitrate; Male; Malondialdehyde; Middle Aged; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species; Tyrosine | 2014 |
Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model.
Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Interleukin-8; Mycobacterium; Mycobacterium Infections; Myeloid Differentiation Factor 88; Neutrophils; Peroxidase; Reactive Nitrogen Species; Receptors, Interleukin-1; Receptors, Interleukin-8B; Signal Transduction; Toll-Like Receptors; Tyrosine; Zebrafish | 2014 |
Oxidative stress and antioxidant status in patients with autoimmune liver diseases.
Topics: Adult; Aged; Aldehydes; Antioxidants; Autoimmune Diseases; Carbon; Catalase; Disease Progression; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hepatitis, Autoimmune; Humans; Isoprostanes; Liver Diseases; Male; Middle Aged; Oxidative Stress; Peroxidase; Superoxide Dismutase; Tyrosine | 2015 |
Kinetics of 3-nitrotyrosine modification on exposure to hypochlorous acid.
Topics: Biomarkers; Chloramines; Chromatography, High Pressure Liquid; Humans; Hypochlorous Acid; Kinetics; Peptide Fragments; Peroxidase; Reactive Nitrogen Species; Tyrosine | 2014 |
Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation.
Topics: Alkynes; Amidohydrolases; Animals; Arginine; Aspartate Aminotransferases; Chromatography, High Pressure Liquid; Cystathionine gamma-Lyase; Endotoxemia; Glutathione; Glycine; Hydrogen Sulfide; Lipopolysaccharides; Liver Diseases; Male; Peroxidase; Rats; Rats, Wistar; Stress, Physiological; Tyrosine | 2014 |
N-acetylcysteine administration confers lung protection in different phases of lung ischaemia-reperfusion injury.
Topics: Acetylcysteine; Administration, Intravenous; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Cytoprotection; Disease Models, Animal; Hemodynamics; I-kappa B Kinase; Inflammation Mediators; Interleukin-1beta; Lipid Peroxidation; Lung; Lung Injury; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
How covalent heme to protein bonds influence the formation and reactivity of redox intermediates of a bacterial peroxidase.
Topics: Bromides; Catalysis; Cyanides; Electrons; Escherichia coli; Heme; Horseradish Peroxidase; Hydrogen Peroxide; Iodides; Iron; Lactoperoxidase; Models, Chemical; Oxidation-Reduction; Oxygen; Peroxidase; Peroxidases; Protein Binding; Protein Processing, Post-Translational; Spectrophotometry; Thiocyanates; Tyrosine | 2014 |
The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Benzenesulfonates; Beverages; Citrus; Colitis; Colon; Disease Models, Animal; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Mice; Neutrophil Infiltration; NF-kappa B; P-Selectin; Peroxidase; Plant Extracts; Poly Adenosine Diphosphate Ribose; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2015 |
Oxidative stress and inflammation in mucopolysaccharidosis type IVA patients treated with enzyme replacement therapy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Blood Proteins; Child; Chondroitinsulfatases; Creatinine; Cytokines; Deoxyguanosine; Enzyme Replacement Therapy; Erythrocytes; Female; Glutathione; Glycosaminoglycans; Humans; Inflammation; Isoprostanes; Male; Mucopolysaccharidosis IV; Oxidative Stress; Peroxidase; Superoxide Dismutase; Treatment Outcome; Tyrosine; Young Adult | 2015 |
Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme.
Topics: Aniline Compounds; Anti-Inflammatory Agents; Catechin; Fluoresceins; Halogenation; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Molsidomine; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Peroxynitrous Acid; Tyrosine | 2015 |
Oxidation of Hypotaurine and Cysteine Sulfinic Acid by Peroxidase-generated Reactive Species.
Topics: Cysteine; Hydrogen Peroxide; Nitrites; Nitrosation; Oxidation-Reduction; Peroxidase; Reactive Oxygen Species; Sulfinic Acids; Sulfonium Compounds; Taurine; Tyrosine | 2015 |
Platelet Glycoprotein IIb/IIIa Inhibitor Tirofiban Ameliorates Cardiac Reperfusion Injury.
Topics: Animals; Apoptosis; In Situ Nick-End Labeling; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Sprague-Dawley; Tirofiban; Tyrosine | 2015 |
Effect of Ambroxol and Beclomethasone on Lipopolysaccharide-Induced Nitrosative Stress in Bronchial Epithelial Cells.
Topics: Ambroxol; Beclomethasone; Bronchi; Cell Line; Chemokine CCL5; Epithelial Cells; Expectorants; Glucocorticoids; Humans; Interleukin-8; Lipopolysaccharides; Neutrophils; Nitric Oxide Synthase Type II; Nitrosation; Peroxidase; Respiratory Mucosa; Stress, Physiological; Tyrosine | 2015 |
Troponin in diabetic patients with and without chronic coronary artery disease.
Topics: Aged; Biomarkers; Case-Control Studies; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Oxidation-Reduction; Peroxidase; Risk Factors; Troponin C; Tyrosine | 2015 |
Key roles of Tyr 10 in Cu bound Aβ complexes and its relevance to Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Copper; Humans; Peptide Fragments; Peroxidase; Protein Aggregation, Pathological; Tyrosine | 2015 |
Peroxidase induced oligo-tyrosine cross-links during polymerization of α-lactalbumin.
Topics: Biopolymers; Cross-Linking Reagents; Lactalbumin; Peroxidase; Tyrosine | 2015 |
Eukaryotic Catalase-Peroxidase: The Role of the Trp-Tyr-Met Adduct in Protein Stability, Substrate Accessibility, and Catalysis of Hydrogen Peroxide Dismutation.
Topics: Catalase; Catalysis; Eukaryotic Cells; Hydrogen Peroxide; Magnaporthe; Methionine; Peroxidase; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Tryptamines; Tyrosine | 2015 |
BML-111 Attenuates Renal Ischemia/Reperfusion Injury Via Peroxisome Proliferator-Activated Receptor-α-Regulated Heme Oxygenase-1.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cell Line; Creatinine; Glucuronidase; Heme Oxygenase-1; Heptanoic Acids; Imidazoles; Leucyl Aminopeptidase; Male; Malondialdehyde; Oxazoles; p38 Mitogen-Activated Protein Kinases; Peroxidase; Phosphorylation; PPAR alpha; Promoter Regions, Genetic; Protoporphyrins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Reperfusion Injury; RNA, Messenger; Tyrosine | 2016 |
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
Topics: Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Halogenation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Mice; Oxidation-Reduction; Peroxidase; Phenanthridines; Tandem Mass Spectrometry; Tyrosine; Vascular Diseases | 2016 |
Dopamine induces lipid accumulation, NADPH oxidase-related oxidative stress, and a proinflammatory status of the plasma membrane in H9c2 cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Caspase 3; Cell Line; Cell Membrane; Cell Survival; Dopamine; Dopamine Agents; Flow Cytometry; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Inflammation; Lipid Metabolism; Microscopy, Electron; Microscopy, Fluorescence; Myoblasts, Cardiac; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Nuclear Proteins; Oxidative Stress; Peroxidase; Rats; Reactive Oxygen Species; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins; Tyrosine | 2016 |
NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA.
Topics: Campylobacter jejuni; Cell Line; Dihydroxyphenylalanine; Drug Resistance, Bacterial; Heme; Host-Pathogen Interactions; Humans; Hydrogen Peroxide; Immune System; Klebsiella pneumoniae; Listeria monocytogenes; NADPH Oxidases; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen; Peroxidase; Phosphotyrosine; Reactive Oxygen Species; Salmonella enterica; Tyrosine | 2016 |
Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy.
Topics: Animals; Biomarkers; Disease Models, Animal; Dogs; Inflammation; Macrophages; Male; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Neutrophils; Oxidation-Reduction; Oxidative Stress; Peroxidase; Tyrosine | 2016 |
Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease.
Topics: Amides; Animals; Anti-Inflammatory Agents; Apoptosis; Body Weight; Colitis; Cyclooxygenase 2; Cytokines; Dicarboxylic Acids; Dinitrofluorobenzene; Ethanolamines; Extracellular Signal-Regulated MAP Kinases; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Mice; NF-kappa B; P-Selectin; Palmitic Acids; Peroxidase; Phosphorylation; PPAR alpha; PPAR gamma; Receptor, Cannabinoid, CB2; Signal Transduction; Tyrosine | 2016 |
Thiol oxidation and di-tyrosine formation in human plasma proteins induced by inflammatory concentrations of hypochlorous acid.
Topics: Apolipoprotein A-I; Biomarkers; Blood Proteins; Blood Specimen Collection; Complement C3; Fibrinogen; Humans; Hypochlorous Acid; Inflammation; Mass Spectrometry; Oxidation-Reduction; Oxidative Stress; Peroxidase; Protein Aggregates; Sulfhydryl Compounds; Tyrosine | 2017 |
Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterial Pressure; Cyclooxygenase 2; Epoprostenol; Gene Expression Regulation, Enzymologic; Heart Rate; Hypotension; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Peroxynitrous Acid; Rats; Rats, Wistar; Ribosomal Protein S6; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine | 2017 |
Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Oxidative Stress; Peroxidase; Renal Insufficiency, Chronic; Risk Factors; Severity of Illness Index; Tyrosine; Young Adult | 2017 |
The nitroxide 4-methoxy TEMPO inhibits neutrophil-stimulated kinase activation in H9c2 cardiomyocytes.
Topics: Animals; Apoptosis; Cell Line; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Humans; Myocytes, Cardiac; Neutrophils; Organ Specificity; Oxidative Stress; Peroxidase; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinases; Protein Transport; Rats; Transferrin; Tyrosine; Ventricular Myosins | 2017 |
Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats.
Topics: Animals; Blood Urea Nitrogen; Cisplatin; Coumaric Acids; Curcumin; Heme Oxygenase (Decyclizing); Kidney; Kidney Diseases; Male; Malondialdehyde; Peroxidase; Protective Agents; Rats, Wistar; RNA, Messenger; Tyrosine | 2017 |
Hemin-Graphene Derivatives with Increased Peroxidase Activities Restrain Protein Tyrosine Nitration.
Topics: Animals; Biocompatible Materials; Catalysis; Cattle; Chromatography, High Pressure Liquid; Free Radicals; Graphite; Hemin; Hydrogen Peroxide; Microscopy, Atomic Force; Nitrates; Nitrites; Oxidation-Reduction; Peroxidase; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2017 |
Myeloperoxidase-derived oxidants damage artery wall proteins in an animal model of chronic kidney disease-accelerated atherosclerosis.
Topics: Animals; Aorta; Atherosclerosis; Blood Urea Nitrogen; Creatinine; Diet, Fat-Restricted; Diet, High-Fat; Dietary Fats; Disease Models, Animal; Disease Progression; Kidney Failure, Chronic; Kidney Function Tests; Lipids; Lipoproteins; Macrophages; Male; Mice; Mice, Knockout; Muscle Proteins; Nephrectomy; Oxidants; Oxidative Stress; Parathyroid Hormone; Peroxidase; Receptors, LDL; Tyrosine; Vasodilation | 2018 |
Protein Kinase C-Delta (PKCδ) Tyrosine Phosphorylation is a Critical Regulator of Neutrophil-Endothelial Cell Interaction in Inflammation.
Topics: Animals; Apoptosis; Bone Marrow Cells; Cell Adhesion; Endothelial Cells; Endothelium, Vascular; Female; Fibronectins; Gene Knock-In Techniques; Inflammation; Male; Mice; Mice, Transgenic; Microcirculation; Microfluidics; Neutrophil Activation; Neutrophils; Oxygen; Permeability; Peroxidase; Phenylalanine; Phosphorylation; Protein Kinase C-delta; Sepsis; Superoxides; Tyrosine | 2019 |
Experimental Woodsmoke Exposure During Exercise and Blood Oxidative Stress.
Topics: Adult; Antioxidants; Cross-Over Studies; Dinoprost; Exercise Test; Humans; Inhalation Exposure; Isoprostanes; Lipid Peroxides; Oxidative Stress; Particulate Matter; Peroxidase; Physical Exertion; Protein Carbonylation; Random Allocation; Smoke; Tyrosine; Uric Acid; Wildfires; Wood; Young Adult | 2018 |
Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation.
Topics: Amino Acids, Aromatic; Animals; Colon; Cytokines; Diet; Dietary Supplements; Epithelial Cells; Female; I-kappa B Kinase; Inflammation; Intestines; Jejunum; Lipopolysaccharides; NF-kappa B; Peroxidase; Phenylalanine; Phosphorylation; Random Allocation; Receptors, Calcium-Sensing; RNA, Messenger; Signal Transduction; Sus scrofa; Swine; Tryptophan; Tumor Necrosis Factor-alpha; Tyrosine | 2018 |
Simultaneous synthesis of l-DOPA and oxidation of d-amino acid by specific coupling of a peroxidase to d-amino acid oxidase.
Topics: Amino Acids; Catalysis; D-Amino-Acid Oxidase; Hydrogen Peroxide; Kinetics; Levodopa; Oxidation-Reduction; Peroxidase; Tyrosine | 2019 |
Myeloperoxidase-Induced Oxidation of Albumin and Ceruloplasmin: Role of Tyrosines.
Topics: Albumins; Antioxidants; Ceruloplasmin; Humans; Oxidation-Reduction; Peroxidase; Tyrosine | 2019 |
Reaction of human peroxidasin 1 compound I and compound II with one-electron donors.
Topics: Electrons; Extracellular Matrix Proteins; Halogenation; HEK293 Cells; Humans; Hydrogen Peroxide; Kinetics; Nitrites; Oxidation-Reduction; Peroxidase; Peroxidasin; Serotonin; Tyrosine; Uric Acid | 2020 |
Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Arginase; beta-N-Acetylhexosaminidases; Catechin; Cell Proliferation; Interleukin-1beta; Interleukin-6; Ki-67 Antigen; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lectins; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Peroxidase; Proliferating Cell Nuclear Antigen; Tea; Triggering Receptor Expressed on Myeloid Cells-1; Tumor Necrosis Factor-alpha; Tyrosine | 2020 |
Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration.
Topics: A549 Cells; Animals; Cell Line; Cell Movement; Cells, Cultured; Cross-Linking Reagents; Extracellular Matrix; Female; Fibronectins; Humans; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Neutrophils; Oxidation-Reduction; Oxidative Stress; Peptide Hydrolases; Peroxidase; Transforming Growth Factor beta1; Tyrosine | 2020 |
The Impact of Hypertension and Metabolic Syndrome on Nitrosative Stress and Glutathione Metabolism in Patients with Morbid Obesity.
Topics: Adult; Area Under Curve; Female; Glutathione; Glutathione Disulfide; Humans; Hypertension; Metabolic Syndrome; Middle Aged; Nitric Oxide; Nitrosative Stress; Obesity, Morbid; Oxidation-Reduction; Peroxidase; Peroxynitrous Acid; ROC Curve; Sulfhydryl Compounds; Tyrosine | 2020 |
Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes.
Topics: Animals; Cardiac Myosins; Cardiomyopathy, Hypertrophic; Carrier Proteins; Cell Line; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertrophy, Left Ventricular; Induced Pluripotent Stem Cells; Male; Mice, Inbred C57BL; Mutation, Missense; Myocardial Contraction; Myocytes, Cardiac; Myosin Heavy Chains; Peroxidase; Phosphorylation; Reactive Oxygen Species; Tyrosine; Ventricular Function, Left | 2022 |
Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage.
Topics: Adenocarcinoma; Animals; Bystander Effect; Colitis; Colorectal Neoplasms; Halogenation; Humans; Indoles; Mice; Mice, Inbred C57BL; Microbiota; Neutrophils; Peroxidase; Tumor Cells, Cultured; Tyrosine | 2021 |
Myeloperoxidase Targets Apolipoprotein A-I for Site-Specific Tyrosine Chlorination in Atherosclerotic Lesions and Generates Dysfunctional High-Density Lipoprotein.
Topics: Adult; Animals; Apolipoprotein A-I; Atherosclerosis; Halogenation; Humans; Injections, Subcutaneous; Lipoproteins, HDL; Mice; Mice, Knockout, ApoE; Peroxidase; Tyrosine | 2021 |
Response of physiological parameters in Dionaea muscipula J. Ellis teratomas transformed with rolB oncogene.
Topics: Agrobacterium; Bacterial Proteins; Carbohydrate Metabolism; Carotenoids; Catalase; DNA, Plant; Droseraceae; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Lipid Metabolism; Malondialdehyde; Oncogenes; Peroxidase; Phenols; Plants, Genetically Modified; Superoxide Dismutase; Transformation, Genetic; Tyrosine | 2021 |
Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage.
Topics: Extracellular Matrix; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Nitrites; Nitrogen Dioxide; Oxidants; Peroxidase; Tryptophan; Tyrosine | 2022 |
An activatable Mn(II) MRI probe for detecting peroxidase activity in vitro and in vivo.
Topics: Animals; Contrast Media; Edetic Acid; Gadolinium DTPA; Horseradish Peroxidase; Hydrogen Peroxide; Magnetic Resonance Imaging; Manganese; Mice; Peroxidase; Phenols; Protons; Tyrosine; Uric Acid; Water | 2022 |