tyrosine and metallothionein

tyrosine has been researched along with metallothionein in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's8 (24.24)18.2507
2000's17 (51.52)29.6817
2010's6 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwamoto, T; Matsuyama, M; Nakashima, I; Nakayama, A; Ohbayashi, M; Takahashi, M; Taniguchi, M1
Kimura, M; Nakajima, K; Otaki, N; Suzuki, K1
Hunziker, PE; Kojima, Y1
Jauch, A; Lutz, WK1
Rainbow, PS; Wong, VW1
Lukashev, ME; Pytela, R; Sheppard, D1
Fujii, T; Hirai, H; Honda, H; Mano, H; Takatoku, M; Witte, ON; Yazaki, Y1
Cox, ME; Maness, PF1
Beckman, JS; Crow, JP; Sampson, JB; Thompson, JA; Zhuang, Y1
Broekaert, D; Eyckerman, S; Tavernier, J; Vandekerckhove, J; Verhee, A; Waelput, W1
Jitsuhara, Y; Kimura, N; Nishiyama, T; Ochi, F; Uchida, M; Yamaguchi, H1
Hidalgo, J; Penkowa, M1
Carrasco, J; Hadberg, H; Hidalgo, J; Molinero, A; Penkowa, M1
Espejo, C; Hidalgo, J; Martínez-Cáceres, EM; Montalban, X; Penkowa, M; Poulsen, CB1
Camats, J; Campbell, IL; Giralt, M; Hadberg, H; Hidalgo, J; Molinero, A; Penkowa, M; Quintana, A; Rojas, S1
Carrasco, J; Florit, S; Giralt, M; Hidalgo, J; Molinero, A; Penkowa, M; Quintana, A1
Hiyoshi, K; Ichinose, T; Inoue, K; Inoue, M; Sadakane, K; Sakurai, M; Sato, M; Shimada, A; Takano, H; Yanagisawa, R; Yoshikawa, T1
Acarin, L; Barbeito, L; Castellano, B; González, B; Peluffo, H1
Cai, L; Kang, YJ; Li, Y; Sun, X; Wang, J; Wang, L; Zhou, Z1
Arteel, GE; Cai, L; Du, Y; Kang, YJ; Li, Y; Saari, JT; Song, Y; Wang, J1
Doser, TA; Fang, CX; Janardhanan, R; Nunn, JM; Quinn, MT; Ren, J; Sreejayan, N; Yang, X; Zhu, M1
Borghi, C; Burlando, B; Dondero, F; Gallo, G; Lanza, C; Panfoli, I; Scarabelli, L; Vergani, L; Viarengo, A1
Cai, L; Chen, T; Kang, YJ; Li, X; Song, Y; Wang, Y; Zhou, G1
Dong, YS; Guo, J; Guo, JB; Han, G; Peng, SQ; Shuai, Y; Zhang, LS1
Haase, H; Rink, L1
Harding, PA; Hoskins, JT; Zhou, Z1
Ahokas, RA; Baburyan, NY; Bhattacharya, SK; Deshmukh, PA; Gandhi, MS; Gerling, IC; Johnson, PL; Kamalov, G; Sun, Y; Weber, KT1
Hansen, PB; Nielsen, SL; Pedersen, MØ; Penkowa, M1
Cai, L; Cong, W; Jin, L; Li, X; Ma, W; Tan, Y; Wang, Y; Zhao, T; Zhu, Z1
Cai, L; Chakrabarti, S; Cong, W; Huang, B; Jin, L; Li, X; Ma, W; Tan, Y; Wang, Y; Zhao, T; Zhu, Z1
Cai, J; Cai, L; Cai, X; Tan, Y; Wang, Y; Zheng, Y; Zhou, S1
Díaz-Ruíz, A; Flores-Espinosa, P; Heras-Romero, Y; Juárez-Rebollar, D; Manjarrez, J; Méndez-Armenta, M; Nava-Ruíz, C; Zaga-Clavellina, V1
Lian, Y; Peng, SQ; Wang, YM; Zhao, J1

Reviews

1 review(s) available for tyrosine and metallothionein

ArticleYear
Signal transduction in monocytes: the role of zinc ions.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2007, Volume: 20, Issue:3-4

    Topics: Humans; Interleukin-1 Receptor-Associated Kinases; Ions; Lipopolysaccharides; Metallothionein; Monocytes; NF-kappa B; Nucleotides, Cyclic; Protein Kinase C; Signal Transduction; Tyrosine; Zinc

2007

Other Studies

32 other study(ies) available for tyrosine and metallothionein

ArticleYear
Establishment and characterization of a malignant melanocytic tumor cell line expressing the ret oncogene.
    Oncogene, 1992, Volume: 7, Issue:8

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Transformation, Neoplastic; Drosophila Proteins; Melanoma, Experimental; Metallothionein; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Transplantation; Oncogenes; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tyrosine

1992
Detection of metallothionein in brain.
    Methods in enzymology, 1991, Volume: 205

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Chromatography, Gel; Humans; Immunoenzyme Techniques; Immunohistochemistry; Indicators and Reagents; Iodine Radioisotopes; Liver; Metallothionein; Mice; Organ Specificity; Radioimmunoassay; Rats; Tyrosine

1991
Amino acid analysis of metallothionein.
    Methods in enzymology, 1991, Volume: 205

    Topics: Amino Acids; Animals; Autoanalysis; Cysteine; Hydrolysis; Indicators and Reagents; Mammals; Metallothionein; Neurospora crassa; Oxidation-Reduction; Tyrosine

1991
Metallothionein protein variants generated in rat liver as a result of DNA and RNA ethylations by the carcinogen diethylnitrosamine.
    Mutation research, 1986, Volume: 164, Issue:6

    Topics: Alkylation; Animals; Cysteine; Diethylnitrosamine; DNA; Genetic Variation; Liver; Male; Metallothionein; Phenylalanine; Rats; Rats, Inbred Strains; RNA; Tyrosine

1986
A modified Lowry assay to measure levels of proteins lacking aromatic amino acid residues (e.g. metallothioneins).
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1984, Volume: 78, Issue:2

    Topics: Metallothionein; Oligopeptides; Proteins; Tryptophan; Tyrosine

1984
Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain.
    The Journal of biological chemistry, 1994, Jul-15, Volume: 269, Issue:28

    Topics: Amino Acid Sequence; Animals; Cell Adhesion; Cell Line; Extracellular Matrix Proteins; Humans; Integrin beta1; Integrins; Kidney; Kinetics; Metallothionein; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Fusion Proteins; Restriction Mapping; Transfection; Tyrosine

1994
Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice.
    Blood, 1995, May-15, Volume: 85, Issue:10

    Topics: Animals; Base Sequence; Clone Cells; DNA Primers; Female; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Genes, abl; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, T-Cell; Male; Metallothionein; Mice; Mice, Transgenic; Molecular Sequence Data; Pedigree; Phosphotyrosine; Promoter Regions, Genetic; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; RNA, Messenger; Tissue Distribution; Tyrosine

1995
Tyrosine phosphorylation of alpha-tubulin is an early response to NGF and pp60v-src in PC12 cells.
    Journal of molecular neuroscience : MN, 1993,Summer, Volume: 4, Issue:2

    Topics: Animals; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Metallothionein; Mice; Neoplasm Proteins; Nerve Growth Factors; Oncogene Protein pp60(v-src); PC12 Cells; Phosphorylation; Phosphotyrosine; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Recombinant Fusion Proteins; Tubulin; Tyrosine

1993
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite.
    Journal of neurochemistry, 1997, Volume: 69, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Binding Sites; Catalysis; Cloning, Molecular; Humans; Kinetics; Liver; Metallothionein; Models, Structural; Mutagenesis, Site-Directed; Mutation; Nitrates; Protein Conformation; Rabbits; Recombinant Proteins; Superoxide Dismutase; Tyrosine; Zinc

1997
Analysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line.
    European cytokine network, 1999, Volume: 10, Issue:4

    Topics: Acute-Phase Proteins; Amino Acid Motifs; Amino Acid Substitution; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Carrier Proteins; Colforsin; DNA-Binding Proteins; Genes, Immediate-Early; Genes, Reporter; Lectins, C-Type; Leptin; Metallothionein; Mice; Mutation; Nerve Growth Factor; Pancreatitis-Associated Proteins; PC12 Cells; Phenylalanine; Proteins; Rats; Receptors, Cell Surface; Receptors, Leptin; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation; Transfection; Tyrosine

1999
N-Glycans protect proteins from protease digestion through their binding affinities for aromatic amino acid residues.
    Journal of biochemistry, 2000, Volume: 127, Issue:3

    Topics: Amino Acids; Animals; Carbohydrate Metabolism; Cattle; Chromatography, High Pressure Liquid; Chymotrypsin; Endopeptidases; Lactalbumin; Metallothionein; Polysaccharides; Protein Binding; Ribonuclease, Pancreatic; Time Factors; Trypsin; Tyrosine

2000
IL-6 deficiency leads to reduced metallothionein-I+II expression and increased oxidative stress in the brain stem after 6-aminonicotinamide treatment.
    Experimental neurology, 2000, Volume: 163, Issue:1

    Topics: 6-Aminonicotinamide; Animals; Antigens, Differentiation; Astrocytes; Blood-Brain Barrier; Bone Marrow Cells; Brain Stem; Encephalitis; Glial Fibrillary Acidic Protein; Hematopoiesis; Immunohistochemistry; Interleukin-6; Macrophages; Malondialdehyde; Metallothionein; Metallothionein 3; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Tissue Proteins; Oxidative Stress; Protein Isoforms; Serum Albumin; T-Lymphocytes; Tyrosine

2000
Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice.
    The European journal of neuroscience, 2000, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Astrocytes; Caspase 1; Caspase 3; Caspases; DNA, Single-Stranded; Epilepsy; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Enzymologic; Glial Fibrillary Acidic Protein; Granulocyte-Macrophage Colony-Stimulating Factor; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Malondialdehyde; Metallothionein; Metallothionein 3; Mice; Mice, Inbred Strains; Mice, Knockout; Microglia; Nerve Degeneration; Nerve Tissue Proteins; NF-kappa B; Nitrogen; Oxidative Stress; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Seizures; Superoxide Dismutase; Tyrosine; Zinc

2000
Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis.
    Journal of neuroimmunology, 2001, Oct-01, Volume: 119, Issue:2

    Topics: Animals; Apoptosis; Encephalomyelitis, Autoimmune, Experimental; Gliosis; In Situ Nick-End Labeling; Interleukin-1; Interleukin-6; Macrophages; Malondialdehyde; Metallothionein; Mice; Mice, Inbred Strains; Mice, Knockout; Microglia; Nerve Degeneration; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; T-Lymphocytes; Tumor Necrosis Factor-alpha; Tyrosine

2001
Astrocyte-targeted expression of interleukin-6 protects the central nervous system during neuroglial degeneration induced by 6-aminonicotinamide.
    Journal of neuroscience research, 2003, Aug-15, Volume: 73, Issue:4

    Topics: 6-Aminonicotinamide; Angiogenesis Inducing Agents; Animals; Apoptosis; Astrocytes; Brain Stem; Cell Count; Central Nervous System; Cytokines; Disease Models, Animal; Gene Targeting; Glial Fibrillary Acidic Protein; Growth Substances; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Lymphocytes; Macrophages; Malondialdehyde; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Nerve Degeneration; Oxidative Stress; Staining and Labeling; Stem Cells; Teratogens; Tyrosine

2003
Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures.
    Journal of neuroscience research, 2005, Feb-15, Volume: 79, Issue:4

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Astrocytes; Cell Count; Cell Death; Central Nervous System Diseases; Epilepsy; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Growth Substances; Guanine; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Interleukins; Kainic Acid; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurodegenerative Diseases; Neurofibrillary Tangles; Staining and Labeling; Tyrosine

2005
Role of metallothionein in antigen-related airway inflammation.
    Experimental biology and medicine (Maywood, N.J.), 2005, Volume: 230, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antigens; Bronchitis; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Deoxyguanosine; Immunohistochemistry; Metallothionein; Mice; Trachea; Tyrosine

2005
Astroglial nitration after postnatal excitotoxic damage: correlation with nitric oxide sources, cytoskeletal, apoptotic and antioxidant proteins.
    Journal of neurotrauma, 2005, Volume: 22, Issue:1

    Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cytoskeletal Proteins; Disease Models, Animal; Female; Male; Metallothionein; Nerve Tissue Proteins; Neurotoxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Long-Evans; Superoxide Dismutase; Tyrosine

2005
Inhibition of superoxide generation and associated nitrosative damage is involved in metallothionein prevention of diabetic cardiomyopathy.
    Diabetes, 2005, Volume: 54, Issue:6

    Topics: Animals; Cardiomyopathies; Diabetes Complications; Gene Expression; Heart Diseases; Male; Metallothionein; Mice; Mice, Transgenic; Nitrosation; Superoxides; Tyrosine

2005
Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury.
    The American journal of pathology, 2005, Volume: 167, Issue:1

    Topics: Aldehydes; Animals; Blotting, Northern; Blotting, Western; Cardiovascular Diseases; Copper; Diabetes Mellitus, Experimental; Endothelin-1; Glutathione; Immunohistochemistry; Interleukin-6; Iron; Metallothionein; Mice; Mice, Transgenic; Myocardium; Oxidative Stress; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Zinc

2005
Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:7

    Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Calcium; Cytochromes c; Diastole; Gene Expression Regulation; Heart Ventricles; Metallothionein; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Oxidative Stress; Pyrogallol; rhoA GTP-Binding Protein; Superoxides; Tyrosine

2006
Efects of growth hormone and cadmium on the transcription regulation of two metallothionein isoforms.
    Molecular and cellular endocrinology, 2007, Jan-15, Volume: 263, Issue:1-2

    Topics: Animals; Cadmium; Calcium; Carcinoma, Hepatocellular; DNA-Binding Proteins; Drug Synergism; Gene Expression Regulation; Growth Hormone; Liver Neoplasms; Metallothionein; Mitogen-Activated Protein Kinases; Oncorhynchus mykiss; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Receptors, Somatotropin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor AP-1; Transcription Factor MTF-1; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine

2007
Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy.
    Journal of the American College of Cardiology, 2006, Oct-17, Volume: 48, Issue:8

    Topics: Actins; Animals; Antioxidants; Apoptosis; Cardiomyopathies; Caspase 3; Cell Death; Cytochromes c; Diabetes Mellitus, Experimental; Enzyme Activation; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Metallothionein; Mice; Mice, Transgenic; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; Oxidative Stress; Sarcomeres; Survival Analysis; Tyrosine

2006
Metallothionein protects against doxorubicin-induced cardiomyopathy through inhibition of superoxide generation and related nitrosative impairment.
    Toxicology letters, 2007, Apr-05, Volume: 170, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Heart; Immunohistochemistry; Male; Metallothionein; Mice; Mice, Knockout; Myocardium; Peroxynitrous Acid; Superoxides; Troponin T; Tyrosine; Zinc

2007
The significance of disulfide bonding in biological activity of HB-EGF, a mutagenesis approach.
    Biochemical and biophysical research communications, 2008, Oct-31, Volume: 375, Issue:4

    Topics: Animals; Cell Line; Cell Nucleus; Cloning, Molecular; Cysteine; Disulfides; ErbB Receptors; Fibroblasts; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Metallothionein; Mice; Mutagenesis, Site-Directed; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Serine; Tyrosine

2008
Coupled calcium and zinc dyshomeostasis and oxidative stress in cardiac myocytes and mitochondria of rats with chronic aldosteronism.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:5

    Topics: Aldehydes; Aldosterone; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Disease Models, Animal; Glutathione Peroxidase; Homeostasis; Hydrogen Peroxide; Hyperaldosteronism; Male; Metallothionein; Mineralocorticoid Receptor Antagonists; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spironolactone; Superoxide Dismutase; Tyrosine; Zinc

2009
Metallothionein-I + II and receptor megalin are altered in relation to oxidative stress in cerebral lymphomas.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain; Cell Cycle Proteins; Cell Proliferation; Central Nervous System Neoplasms; DNA-Binding Proteins; Guanine; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Low Density Lipoprotein Receptor-Related Protein-2; Lymph Nodes; Lymphoma, Large B-Cell, Diffuse; Malondialdehyde; Metallothionein; Middle Aged; Minichromosome Maintenance Complex Component 7; Nuclear Proteins; Oxidative Stress; Tyrosine

2010
Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374).
    American journal of physiology. Endocrinology and metabolism, 2013, Apr-15, Volume: 304, Issue:8

    Topics: Animals; Coenzyme A-Transferases; Diabetes Mellitus, Experimental; Disease Models, Animal; Energy Metabolism; Heart Diseases; Male; Metallothionein; Mice; Mice, Inbred Strains; Mice, Transgenic; Myocardium; Nitrogen; Protein Structure, Tertiary; Superoxides; Tryptophan; Tyrosine

2013
Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Dietary Supplements; Enzyme Activation; Male; Metallothionein; Mice, Transgenic; Mitochondrial Proton-Translocating ATPases; Myocardium; Protein Subunits; Streptozocin; Superoxides; Tyrosine; Zinc

2014
Deletion of metallothionein exacerbates intermittent hypoxia-induced oxidative and inflammatory injury in aorta.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Aldehydes; Animals; Aorta; Apoptosis; Connective Tissue Growth Factor; Hypoxia; Metallothionein; Mice; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine

2014
Metallothionein expression in the rat brain following KA and PTZ treatment.
    Environmental toxicology and pharmacology, 2015, Volume: 40, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Epilepsy; Kainic Acid; Male; Metallothionein; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Tyrosine

2015
Metallothionein protects against isoniazid-induced liver injury through the inhibition of CYP2E1-dependent oxidative and nitrosative impairment in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 102

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Isoniazid; Lipid Peroxidation; Liver; Male; Metallothionein; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Tyrosine

2017