tyrosine and maleylacetone

tyrosine has been researched along with maleylacetone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dixit, V; Guo, X; Henderson, GN; James, MO; Liu, H; Shroads, AL; Stacpoole, PW1
Henderson, GN; Jia, M; Liu, H; Stacpoole, PW; Zolodz, MD1
Bullock, JR; Coats, BS; Gong, Y; Johnson, JA; Kurtz, TL; Langaee, T; Ostrov, DA; Shroads, AL; Stacpoole, PW; Wagner, DA; Weithorn, D1
Abdelmalak, MM; Daigle, AD; James, MO; Maisenbacher, HW; Mincey, BD; Samper, IS; Shroads, AL; Stacpoole, PW; Zhong, G1
Coats, BS; Langaee, T; McDonough, CW; Shroads, AL; Stacpoole, PW1
Coats, BS; Langaee, T; Shroads, AL; Shuster, JJ; Stacpoole, PW1

Trials

2 trial(s) available for tyrosine and maleylacetone

ArticleYear
Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:1

    Topics: Acetone; Adolescent; Adult; Aminolevulinic Acid; Child; Child, Preschool; Dichloroacetic Acid; Double-Blind Method; Female; Genetic Diseases, Inborn; Glutathione Transferase; Haplotypes; Humans; Infant; Kinetics; Male; Maleates; Mitochondrial Diseases; Polymorphism, Single Nucleotide; Tyrosine; Young Adult

2015
Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans.
    Drug metabolism and personalized therapy, 2015, Volume: 30, Issue:1

    Topics: Acetone; Adult; Biomarkers; Chloral Hydrate; cis-trans-Isomerases; Dichloroacetic Acid; Female; Glutathione Transferase; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Maleates; Tyrosine; Young Adult

2015

Other Studies

4 other study(ies) available for tyrosine and maleylacetone

ArticleYear
Inhibition and recovery of rat hepatic glutathione S-transferase zeta and alteration of tyrosine metabolism following dichloroacetate exposure and withdrawal.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1

    Topics: Acetone; Administration, Oral; Aging; Animals; Blotting, Western; Body Weight; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Drug Administration Schedule; Glutathione Transferase; Humans; Liver; Male; Maleates; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine

2006
A GC-MS/MS method for the quantitative analysis of low levels of the tyrosine metabolites maleylacetone, succinylacetone, and the tyrosine metabolism inhibitor dichloroacetate in biological fluids and tissues.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jun-06, Volume: 837, Issue:1-2

    Topics: Acetone; Animals; Blotting, Western; Dichloroacetic Acid; Gas Chromatography-Mass Spectrometry; Heptanoates; Humans; Liver; Male; Maleates; Rats; Sensitivity and Specificity; Tyrosine

2006
Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:6

    Topics: Acetone; Adult; Amino Acid Substitution; Dichloroacetic Acid; Environmental Pollutants; Enzyme Stability; Female; Florida; Genetic Association Studies; Glutathione Transferase; Half-Life; Humans; Male; Maleates; Middle Aged; Models, Molecular; Mutation; Polymorphism, Single Nucleotide; Protein Conformation; Tyrosine; Young Adult

2012
Pharmacokinetics of oral dichloroacetate in dogs.
    Journal of biochemical and molecular toxicology, 2013, Volume: 27, Issue:12

    Topics: Acetone; Analysis of Variance; Animals; Area Under Curve; Blotting, Western; cis-trans-Isomerases; Dichloroacetic Acid; Dogs; Glutathione Transferase; Half-Life; Injections, Intravenous; Male; Maleates; Tyrosine

2013