tyrosine has been researched along with leupeptins in 37 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (21.62) | 18.7374 |
1990's | 8 (21.62) | 18.2507 |
2000's | 14 (37.84) | 29.6817 |
2010's | 7 (18.92) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fridman, R; Hamilton, TC; Kanemoto, T; Martin, GR | 1 |
Edwards, RH; MacLennan, PA; McArdle, A | 1 |
Angerås, U; Benson, D; Fischer, JE; Hall-Angerås, M; Hasselgren, PO; James, JH | 1 |
Hamilton, G; Karner, J; Kovats, E; Ollenschläger, G; Roth, E; Simmel, A | 1 |
Karner, J; Kovats, E; Ollenschläger, G; Roth, E; Simmel, A | 1 |
Odessey, R | 1 |
Bolli, R; Cannon, RO; Epstein, SE; Goldstein, RE; Speir, E | 1 |
Fujii, S; Hitomi, Y; Honda, T; Niinobe, M | 1 |
Cable, HC; Duncan, R; Kopecek, J; Lloyd, JB; Rejmanová, P | 1 |
Fujimoto, T; Kambayashi, J; Kosaki, G; Nomura, T | 1 |
Bolli, R; Davenport, NJ; Epstein, SE; Goldstein, RE | 1 |
Baldin, V; Cans, C; Ducommun, B; Knibiehler, M | 1 |
Fang, CH; Fischer, JE; Hasselgren, PO; Hobler, S; Li, BG; Wang, JJ | 1 |
Chrétien, S; Gisselbrecht, S; Lacombe, C; Mayeux, P; Muller, O; Varlet, P; Verdier, F; Yoshimura, A | 1 |
Hasselgren, PO; Luo, GJ; Wang, JJ; Wang, L | 1 |
Baron, R; Bartkiewicz, M; Horne, WC; Houghton, A; Kondo, T; Yokouchi, M; Yoshimura, A; Zhang, H | 1 |
Carpino, N; Feng, J; Ihle, JN; Marine, JC; Moriggl, R; Stravopodis, D; Teglund, S; Wang, D | 1 |
Aggarwal, BB; Manna, SK; Mukhopadhyay, A | 1 |
Hildebrand, WH; Lutz, CT; Prilliman, KR; Solheim, JC; Thomas, HJ; Turnquist, HR | 1 |
Hilton, DJ; Junttila, I; Saharinen, P; Silvennoinen, O; Ungureanu, D | 1 |
Cederbaum, AI; Pérez, MJ | 1 |
Freund, GG; O'Connor, JC | 1 |
Na, BK; Pandey, KC; Rosenthal, PJ; Sijwali, PS; Singh, A | 1 |
Augustin, HG; Fellner, D; Kroll, J; Leptien, K; Nacak, TG | 1 |
Song, P; Wang, S; Wu, Y; Xu, J; Zhang, M; Zou, MH | 1 |
Massone, S; Munteanu, A; Ricciarelli, R; Zingg, JM | 1 |
Sarge, KD; Zhang, J | 1 |
Callahan, LA; Supinski, GS; Vanags, J | 1 |
Dong, LQ; Fang, Q; Jia, W; Liu, F; Liu, M; Liu, X; Zhang, J; Zhou, L | 1 |
Song, P; Wang, S; Wu, Y; Xu, J; Zou, MH | 1 |
Brand, C; Brodie, C; Horovitz-Fried, M; Inbar, A; Sampson, SR | 1 |
He, X; Kermode, AR | 1 |
Asfa, S; Wang, Q; Wang, S; Xu, J; Zhang, M; Zou, MH | 1 |
Cai, J; Lin, B; Qu, J; Snider, BJ; Sun, L; Wu, M; Wu, S | 1 |
Cai, L; Cui, W; Fu, Y; Miao, L; Miao, X; Su, G; Sun, W; Tan, Y; Wang, B; Wang, Y; Xin, Y | 1 |
Sato, F; Yamada, Y | 1 |
Ayewoh, EN; Chothe, PP; Czuba, LC; Swaan, PW | 1 |
37 other study(ies) available for tyrosine and leupeptins
Article | Year |
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Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Topics: Amides; Amino Acid Sequence; Aminocaproates; Antineoplastic Agents; Benzamidines; Biocompatible Materials; Cell Adhesion; Cell Line; Chemotaxis; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Female; Glycoproteins; Humans; In Vitro Techniques; Laminin; Leupeptins; Metalloendopeptidases; Molecular Sequence Data; Neoplasm Invasiveness; Oligopeptides; Ovarian Neoplasms; Pepstatins; Polyamines; Protease Inhibitors; Proteoglycans; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured; Tyrosine | 1991 |
Effects of calcium on protein turnover of incubated muscles from mdx mice.
Topics: Animals; Calcium; Cycloheximide; Kinetics; Leupeptins; Methylamines; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscles; Muscular Dystrophy, Animal; Proteins; Tyrosine | 1991 |
Regulation of total and myofibrillar protein breakdown in rat extensor digitorum longus and soleus muscle incubated flaccid or at resting length.
Topics: Animals; Insulin; Kinetics; Leupeptins; Male; Methylhistidines; Muscle Proteins; Muscles; Myofibrils; Rats; Rats, Inbred Strains; Tyrosine | 1990 |
Influence of leupeptin on protein and amino-acid metabolism in septic rats.
Topics: Amino Acids; Animals; Bacterial Infections; Body Weight; Eating; Leupeptins; Liver; Muscles; Oligopeptides; Proteins; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Increased mortality in septic rats after leupeptin application.
Topics: Animals; Bacterial Infections; Body Weight; Creatinine; Leupeptins; Liver; Male; Muscles; Oligopeptides; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Effect of inhibitors of proteolysis and arachidonic acid metabolism on burn-induced protein breakdown.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Hindlimb; Ibuprofen; In Vitro Techniques; Indomethacin; Leupeptins; Lysosomes; Muscles; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Proteins; Quinacrine; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Role of cellular proteinases in acute myocardial infarction. I. Proteolysis in nonischemic and ischemic rat myocardium and the effects of antipain, leupeptin, pepstatin and chymostatin administered in vivo.
Topics: Animals; Antipain; Cathepsins; Cell Survival; Chymotrypsin; Endopeptidases; Heart; Leupeptins; Male; Myocardial Infarction; Myocardium; Oligopeptides; Pepstatins; Protease Inhibitors; Rats; Rats, Inbred Strains; Time Factors; Tyrosine | 1983 |
Cytochemical demonstrations of protease in human peripheral blood cells by use of new alpha-naphthyl ester substrates.
Topics: Chymotrypsin; Histocytochemistry; Humans; Iodoacetates; Iodoacetic Acid; Isoflurophate; Leukocytes; Leupeptins; Lysine; Male; Naphthols; Neutrophils; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity; Tyrosine | 1983 |
Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers.
Topics: 2,4-Dinitrophenol; Acrylamides; Animals; Chromatography, Gel; Dinitrophenols; Female; Kinetics; Leupeptins; Pinocytosis; Polymers; Rats; Tyrosine; Yolk Sac | 1984 |
The analysis of platelet reaction, utilizing various inhibitors of platelet aggregation.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Gabexate; Guanidines; Humans; Leupeptins; Platelet Aggregation; Protease Inhibitors; Tosyl Compounds; Tyrosine | 1980 |
Myocardial proteolysis during acute myocardial ischaemia.
Topics: Animals; Coronary Disease; Dogs; Female; Hydrolysis; In Vitro Techniques; Leupeptins; Male; Myocardium; Proteins; Tyrosine | 1983 |
Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation.
Topics: Calpain; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cysteine Endopeptidases; HeLa Cells; Humans; Leupeptins; Multienzyme Complexes; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Threonine; Tyrosine | 1997 |
Proteasome blockers inhibit protein breakdown in skeletal muscle after burn injury in rats.
Topics: Acetylcysteine; Animals; Burns; Culture Techniques; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Lactones; Leupeptins; Male; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tyrosine; Ubiquitins | 1998 |
Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein.
Topics: Acetylcysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; Immediate-Early Proteins; Leupeptins; Milk Proteins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Receptors, Erythropoietin; Signal Transduction; src Homology Domains; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Tyrosine; Ubiquitins | 1998 |
Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes.
Topics: Adenosine Triphosphate; Animals; Calcium; Calpain; Cathepsin B; Cathepsin D; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Deoxyglucose; Dexamethasone; Leucine; Leupeptins; Methylamines; Mifepristone; Multienzyme Complexes; Muscle, Skeletal; Proteasome Endopeptidase Complex; Proteins; Rats; Tyrosine; Ubiquitins | 1998 |
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7.
Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Epidermal Growth Factor; ErbB Receptors; Leupeptins; Ligands; Ligases; Models, Biological; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Recombinant Fusion Proteins; Two-Hybrid System Techniques; Tyrosine; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitins; Zinc Fingers | 1999 |
A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5.
Topics: Acetylcysteine; Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Leupeptins; Milk Proteins; Multienzyme Complexes; Phosphorylation; Phosphotyrosine; Proteasome Endopeptidase Complex; Protein Structure, Secondary; STAT5 Transcription Factor; Trans-Activators; Transcriptional Activation; Tyrosine | 2000 |
Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha.
Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; HeLa Cells; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Transcription, Genetic; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells; Vanadates | 2000 |
HLA-B polymorphism affects interactions with multiple endoplasmic reticulum proteins.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antiporters; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Calcium-Binding Proteins; Calreticulin; Cysteine Endopeptidases; Endoplasmic Reticulum; HLA-B7 Antigen; Humans; Immunoglobulin G; Immunoglobulins; Leupeptins; Membrane Transport Proteins; Multienzyme Complexes; Mutagenesis, Site-Directed; Polymorphism, Genetic; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Binding; Rabbits; Ribonucleoproteins; Serine; Tyrosine | 2000 |
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.
Topics: Animals; Carrier Proteins; Cell Fractionation; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Interferon-gamma; Interleukin-3; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Leupeptins; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Repressor Proteins; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Tyrosine; Ubiquitin | 2002 |
Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.
Topics: Antioxidants; Arachidonic Acid; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cysteine Endopeptidases; Cytochrome P-450 CYP2E1; Drug Synergism; Endopeptidases; Humans; Iron; Leupeptins; Lipid Peroxides; Liver Neoplasms; Lysosomes; Membrane Potentials; Mitochondria, Liver; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Tyrosine | 2003 |
Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.
Topics: Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Synergism; Glucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Leupeptins; Multienzyme Complexes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Sirolimus; Tyrosine; Vanadates | 2003 |
Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cloning, Molecular; Cysteine Endopeptidases; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Immunoblotting; Kinetics; Leupeptins; Molecular Sequence Data; Plasmodium; Plasmodium falciparum; Protein Folding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Tyrosine | 2004 |
The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis.
Topics: Actins; Amino Acid Chloromethyl Ketones; Amino Acid Motifs; Amino Acid Sequence; Aorta; Apoptosis; Autoantigens; Blotting, Northern; Blotting, Western; Brefeldin A; Cell Line; Cells, Cultured; Cloning, Molecular; Endoplasmic Reticulum; Endothelium, Vascular; Golgi Apparatus; Golgi Matrix Proteins; HeLa Cells; Humans; Leupeptins; Membrane Glycoproteins; Membrane Proteins; Microscopy, Confocal; Molecular Sequence Data; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic; Transfection; Tyrosine; Ubiquitin; Umbilical Veins | 2006 |
Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus.
Topics: Animals; Antioxidants; Aorta; Biopterins; Cells, Cultured; Cyclic N-Oxides; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Endothelial Cells; Glucose; GTP Cyclohydrolase; Guanosine Triphosphate; Leupeptins; Mice; Mice, Inbred C57BL; Nitrogen; Organ Culture Techniques; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species; Spin Labels; Tyrosine; Ubiquitin; Umbilical Veins | 2007 |
Modulation of proteasome activity by vitamin E in THP-1 monocytes.
Topics: Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Humans; Intracellular Signaling Peptides and Proteins; Leupeptins; Monocytes; Oxidative Stress; Protease Inhibitors; Proteasome Endopeptidase Complex; Ritonavir; Tocopherols; Tocotrienols; Tumor Suppressor Protein p53; Tyrosine; Vitamin E | 2007 |
Identification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome system.
Topics: Amino Acid Sequence; Cells, Cultured; Cysteine; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Nuclear Proteins; Polycomb Repressive Complex 1; Polymorphism, Single Nucleotide; Proteasome Endopeptidase Complex; Protein Denaturation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Repressor Proteins; RING Finger Domains; Transfection; Tyrosine; Ubiquitin | 2009 |
Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction.
Topics: Animals; Atrophy; Boronic Acids; Bortezomib; Caspase 3; Cysteine Proteinase Inhibitors; Diaphragm; Endotoxemia; Enzyme Activation; Leupeptins; Male; Muscle Contraction; Muscle Weakness; Oligopeptides; Organ Size; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley; Sepsis; Tyrosine | 2009 |
Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Autophagy; Disease Models, Animal; Down-Regulation; Endoplasmic Reticulum; Humans; Insulin Resistance; Leupeptins; Mice; Mice, Inbred Strains; Obesity; Phosphorylation; Receptor, Insulin; Taurochenodeoxycholic Acid; Tyrosine | 2009 |
Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Biopterins; Blood Pressure; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelial Cells; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Hypertension; In Vitro Techniques; Leupeptins; Mice; Mice, Inbred C57BL; Nitrates; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; RNA, Small Interfering; Transfection; Tyrosine; Vasodilation | 2009 |
Insulin stimulation of PKCδ triggers its rapid degradation via the ubiquitin-proteasome pathway.
Topics: Amino Acid Substitution; Animals; Blotting, Western; Cell Line; Cysteine Proteinase Inhibitors; Hypoglycemic Agents; Insulin; Leupeptins; Muscle, Skeletal; Myoblasts; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase C-delta; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Ubiquitin; Ubiquitination | 2010 |
Programmed cell death of the megagametophyte during post-germinative growth of white spruce (Picea glauca) seeds is regulated by reactive oxygen species and the ubiquitin-mediated proteolytic system.
Topics: Amino Acid Sequence; Apoptosis; Catalase; Cloning, Molecular; Cysteine Proteinase Inhibitors; DNA, Plant; Germination; Hydrogen Peroxide; Leupeptins; Lipid Peroxidation; Molecular Sequence Data; Ovule; Phosphorylation; Picea; Proteasome Endopeptidase Complex; Reactive Oxygen Species; Seeds; Sequence Alignment; Tyrosine; Ubiquitin; Ubiquitination | 2010 |
Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors.
Topics: Animals; Blotting, Western; Cardiovascular Diseases; Cells, Cultured; Cysteine Proteinase Inhibitors; Diabetes Mellitus, Experimental; Dyslipidemias; Endothelium, Vascular; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Leupeptins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrosation; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Receptors, LDL; Risk Factors; RNA Interference; Thioredoxins; Tyrosine | 2012 |
Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.
Topics: Aldehydes; Anilides; Cells, Cultured; Cysteine Proteinase Inhibitors; Electrophoretic Mobility Shift Assay; Humans; Lactones; Leupeptins; Oxazoles; Oxidative Stress; PPAR alpha; Retinal Pigment Epithelium; Tyrosine; Vitamin K 3 | 2012 |
Therapeutic effect of MG132 on the aortic oxidative damage and inflammatory response in OVE26 type 1 diabetic mice.
Topics: Albuminuria; Animals; Aorta; Blood Pressure; Diabetes Mellitus, Experimental; Hyperglycemia; Leupeptins; Mice; Mice, Transgenic; NF-E2-Related Factor 2; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2013 |
Tyrosine phosphorylation and protein degradation control the transcriptional activity of WRKY involved in benzylisoquinoline alkaloid biosynthesis.
Topics: Alkaloids; Benzylisoquinolines; Cell Nucleus; Cells, Cultured; Coptis; DNA; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Plant; Immunoprecipitation; Leupeptins; Mutagenesis, Site-Directed; Phosphorylation; Plant Cells; Plant Proteins; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Transcription Factors; Transcriptional Activation; Tyrosine | 2016 |
Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (
Topics: Animals; Caco-2 Cells; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Intestinal Mucosa; Leupeptins; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Dependent; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Protein Stability; Protein Tyrosine Phosphatases; Proteolysis; Pyrimidines; src-Family Kinases; Symporters; Tyrosine; Vanadates | 2019 |