tyrosine has been researched along with leflunomide in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cherwinski, HM; Devens, B; McCarley, D; Ransom, JT; Schatzman, R | 1 |
| Blinder, L; Chong, AS; Gong, H; Shen, J; Williams, JW; Xu, X | 1 |
| Chong, AS; Finnegan, A; Gong, H; Jäck, HM; Siemasko, K; Williams, JW | 1 |
| Blinder, L; Chong, AS; Huang, W; Mall, JW; Myers, JA; Saclarides, TJ; Shen, J; Williams, JW; Xu, X | 1 |
| Dimitrova, P; Herrmann, ML; Kalden, JR; Schleyerbach, R; Schulze-Koops, H; Skapenko, A | 1 |
| Cho, ML; Jhun, JY; Kim, EK; Lee, HJ; Lee, WS; Min, JK; Moon, SJ; Park, SH | 1 |
6 other study(ies) available for tyrosine and leflunomide
| Article | Year |
|---|---|
The immunosuppressant leflunomide inhibits lymphocyte progression through cell cycle by a novel mechanism.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Cycle; Female; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Isoxazoles; Leflunomide; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Interleukin-2; Tumor Cells, Cultured; Tyrosine | 1995 |
Control of lymphoproliferative and autoimmune disease in MRL-lpr/lpr mice by brequinar sodium: mechanisms of action.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Biphenyl Compounds; Cytidine Triphosphate; Female; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphoproliferative Disorders; Mice; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Phosphorylation; Tyrosine; Uridine; Uridine Triphosphate | 1997 |
Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production.
Topics: Animals; B-Lymphocytes; Binding, Competitive; DNA-Binding Proteins; Growth Inhibitors; Immunoglobulin G; Immunosuppressive Agents; Interleukin-4; Isoxazoles; Janus Kinase 3; Leflunomide; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; STAT6 Transcription Factor; Trans-Activators; Tyrosine; Uridine | 1998 |
In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action.
Topics: 3T3 Cells; Adjuvants, Immunologic; Aniline Compounds; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Crotonates; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Glioma; Hydroxybutyrates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitriles; Phosphorylation; Pyrimidine Nucleotides; Receptors, Growth Factor; Receptors, Platelet-Derived Growth Factor; Toluidines; Tumor Cells, Cultured; Tyrosine | 1999 |
Restriction of de novo pyrimidine biosynthesis inhibits Th1 cell activation and promotes Th2 cell differentiation.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Female; Humans; Immunologic Memory; Immunosuppressive Agents; Interphase; Intracellular Fluid; Isoxazoles; Leflunomide; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phosphorylation; Pyrimidines; Stem Cells; Th1 Cells; Th2 Cells; Tyrosine; Uridine Triphosphate | 2002 |
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Differentiation; Crotonates; Forkhead Transcription Factors; Heme Oxygenase-1; Humans; Hydroxybutyrates; Inflammation; Isoxazoles; Jurkat Cells; Leflunomide; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Nitriles; Oxidative Stress; Signal Transduction; Spleen; Th17 Cells; Toluidines; Tyrosine | 2017 |