tyrosine and kainic acid

tyrosine has been researched along with kainic acid in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (20.00)18.2507
2000's15 (60.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellmann, R; Maas, D; Marksteiner, J; Meyer, DK; Olenik, C; Sperk, G; Widmann, R1
Hong, KS; Kaibuchi, K; Kim, YS; Kishi, K; Kuroda, S; Park, JB; Seong, YS; Takai, Y1
Doi, K; Sekiguchi, M; Wada, K; Watase, K; Wenthold, RJ; Yokotani, N; Zhu, WS1
Ayata, C; Ayata, G; Beal, MF; Christie, RH; Endres, M; Ferrante, RJ; Hara, H; Huang, PL; Hyman, BT; Kim, A; Matthews, RT; Moskowitz, MA; Waeber, C1
Baudry, M; Doctrow, SR; Rong, Y; Tocco, G1
Anderson, CM; Chan, PH; Chen, Y; Copin, JC; Fahlman, CS; Stein, BA; Swanson, RA; Ying, W1
Carrasco, J; Hadberg, H; Hidalgo, J; Molinero, A; Penkowa, M1
Boeckers, TM; de la Cerda, A; Grimm, R; Gundelfinger, ED; Marengo, JJ; Orrego, F; Smalla, KH; Soto, D; Tischmeyer, W; Wolf, G; Wyneken, U1
Gurd, JW; Ikeda-Douglas, CJ; Milgram, NW; Moussa, RC; Thakur, V1
Korpi, ER; Lovinger, DM; Möykkynen, T1
Anesetti, G; Barbeito, L; Beckman, JS; Cassina, P; Castellanos, R; Martinez-Palma, L; Pehar, M; Peluffo, H1
Behl, C; Conrad, S; Goodenough, S; Skutella, T1
Ambrósio, AF; Araújo, IM; Carvalho, CM; Verdasca, MJ1
Carrasco, J; Florit, S; Giralt, M; Hidalgo, J; Molinero, A; Penkowa, M; Quintana, A1
Behl, C; Goodenough, S; Pietrzik, C; Schleusner, D; Skutella, T1
Egebjerg, J; Gajhede, M; Geballe, MT; Holm, MM; Kastrup, JS; Naur, P; Traynelis, SF; Vestergaard, B1
Green, T; Nanao, MH; Nayeem, N; Zhang, Y1
Aono, S; Hayakawa, M; Ida, M; Kakizawa, H; Kojima, S; Kuroda, Y; Maeda, H; Matsui, F; Nakanishi, K; Oohira, A; Saito, A; Sato, Y; Tokita, Y1
Champeil, E; Proni, G; Sapse, D1
Boccitto, M; Clardy, J; Driscoll, M; Georgiades, SN; Kalb, RG; Liu, Y; Mano, I; Merry, D; Mojsilovic-Petrovic, J; Nedelsky, N; Neve, RL; Taylor, JP; Zhou, W1
Ishikawa, T; Kuroda, S; Matsumoto, Y; Okamoto, M; Suemitsu, S; Usui, S; Watanabe, M; Yamada, N; Yokobayashi, E1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Liang, LP; Patel, M; Rivard, C; Ryan, K1
Díaz-Ruíz, A; Flores-Espinosa, P; Heras-Romero, Y; Juárez-Rebollar, D; Manjarrez, J; Méndez-Armenta, M; Nava-Ruíz, C; Zaga-Clavellina, V1
Kim, UJ; Lee, BH; Lee, KH1

Other Studies

25 other study(ies) available for tyrosine and kainic acid

ArticleYear
Enhanced rate of expression and biosynthesis of neuropeptide Y after kainic acid-induced seizures.
    Journal of neurochemistry, 1991, Volume: 56, Issue:2

    Topics: Amygdala; Animals; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Frontal Lobe; Gene Expression; Hippocampus; Kainic Acid; Male; Neuropeptide Y; Nucleic Acid Hybridization; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Seizures; Tritium; Tyrosine

1991
Phosphorylation and activation of mitogen-activated protein kinase by kainic acid-induced seizure in rat hippocampus.
    Biochemical and biophysical research communications, 1994, Jul-29, Volume: 202, Issue:2

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Hippocampus; Immunoblotting; Immunosorbent Techniques; Kainic Acid; Kinetics; Male; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Seizures; Tyrosine

1994
A deletion in the second cytoplasmic loop of GluR3 produces a dominant negative mutant of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Amino Acid Sequence; Animals; Cell Line; Cytoplasm; Evoked Potentials; Female; Glycine; Kainic Acid; Molecular Sequence Data; Mutagenesis; Oocytes; Protein Biosynthesis; Protein Structure, Secondary; Receptors, AMPA; Restriction Mapping; Sequence Deletion; Transfection; Tyrosine; Xenopus laevis

1994
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Sep-15, Volume: 17, Issue:18

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Binding Sites; Corpus Striatum; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine

1997
EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Aug-17, Volume: 96, Issue:17

    Topics: Animals; Catalase; Electrophoresis, Polyacrylamide Gel; Kainic Acid; Molecular Mimicry; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spectrin; Superoxide Dismutase; Tyrosine

1999
Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:2

    Topics: Animals; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Humans; Hydrazines; Kainic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Reactive Oxygen Species; Spermine; Superoxide Dismutase; Tyrosine; Vitamin K

2000
Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice.
    The European journal of neuroscience, 2000, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Astrocytes; Caspase 1; Caspase 3; Caspases; DNA, Single-Stranded; Epilepsy; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Enzymologic; Glial Fibrillary Acidic Protein; Granulocyte-Macrophage Colony-Stimulating Factor; Hippocampus; In Situ Nick-End Labeling; Kainic Acid; Male; Malondialdehyde; Metallothionein; Metallothionein 3; Mice; Mice, Inbred Strains; Mice, Knockout; Microglia; Nerve Degeneration; Nerve Tissue Proteins; NF-kappa B; Nitrogen; Oxidative Stress; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Seizures; Superoxide Dismutase; Tyrosine; Zinc

2000
Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities.
    Neuroscience, 2001, Volume: 102, Issue:1

    Topics: Animals; Cytoskeleton; Disease Models, Animal; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Kainic Acid; Male; Nerve Tissue Proteins; Neurons; Phosphorylation; Prosencephalon; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; SAP90-PSD95 Associated Proteins; Seizures; Subcellular Fractions; Synaptic Membranes; Tyrosine

2001
Seizure activity results in increased tyrosine phosphorylation of the N-methyl-D-aspartate receptor in the hippocampus.
    Brain research. Molecular brain research, 2001, Nov-01, Volume: 95, Issue:1-2

    Topics: Animals; Blotting, Western; Detergents; Electrophoresis, Polyacrylamide Gel; Hippocampus; Kainic Acid; Male; Phosphorylation; Precipitin Tests; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Seizures; Solubility; Tyrosine

2001
Ethanol inhibits alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function in central nervous system neurons by stabilizing desensitization.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Substitution; Animals; Benzothiadiazines; Cells, Cultured; Central Nervous System; Central Nervous System Depressants; Drug Interactions; Ethanol; Excitatory Amino Acid Agonists; Humans; Kainic Acid; Leucine; Membrane Potentials; Mice; Mice, Inbred C57BL; Mutation; Neurons; Pyramidal Cells; Receptors, AMPA; Tyrosine

2003
Involvement of nitric oxide on kainate-induced toxicity in oligodendrocyte precursors.
    Neurotoxicity research, 2003, Volume: 5, Issue:6

    Topics: Animals; Animals, Newborn; Cell Count; Cell Death; Cells, Cultured; Culture Media; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique; Kainic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodendroglia; Peroxynitrous Acid; Quinoxalines; Rats; Rats, Wistar; Spinal Cord; Stem Cells; Tyrosine

2003
Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo.
    Brain research, 2004, Nov-05, Volume: 1026, Issue:1

    Topics: Animals; Behavior, Animal; Blotting, Western; Butadienes; Cell Death; Cell Survival; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Lithium Chloride; Male; Mice; Mitogen-Activated Protein Kinase 1; Neurotoxicity Syndromes; Nitriles; Organ Culture Techniques; Phosphorylation; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine

2004
Nitric oxide inhibits complex I following AMPA receptor activation via peroxynitrite.
    Neuroreport, 2004, Sep-15, Volume: 15, Issue:13

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Benzothiadiazines; Cells, Cultured; Cyclic GMP; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Immunohistochemistry; Kainic Acid; Microtubule-Associated Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Proton Pumps; Quinoxalines; Rats; Receptors, AMPA; Tyrosine

2004
Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures.
    Journal of neuroscience research, 2005, Feb-15, Volume: 79, Issue:4

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Astrocytes; Cell Count; Cell Death; Central Nervous System Diseases; Epilepsy; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Growth Substances; Guanine; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Interleukins; Kainic Acid; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurodegenerative Diseases; Neurofibrillary Tangles; Staining and Labeling; Tyrosine

2005
Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes.
    Neuroscience, 2005, Volume: 132, Issue:3

    Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Agonists; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Phosphorylation; Pregnancy; Propidium; Rats; Rats, Sprague-Dawley; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Tyrosine

2005
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
    The Journal of biological chemistry, 2005, Oct-21, Volume: 280, Issue:42

    Topics: Alanine; Animals; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ions; Kainic Acid; Kinetics; Ligands; Models, Biological; Models, Chemical; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; RNA, Complementary; Tryptophan; Tyrosine; Xenopus laevis

2005
Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-27, Volume: 26, Issue:39

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Cell Line; Dimerization; GluK2 Kainate Receptor; Glutamic Acid; Humans; Hydrogen Bonding; Kainic Acid; Kidney; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Protein Binding; Protein Conformation; Protein Denaturation; Protein Interaction Mapping; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection; Tyrosine

2006
A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death.
    Journal of neurochemistry, 2008, Volume: 104, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caspase 3; Cell Death; Cell Survival; Chondroitin Sulfates; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Polyelectrolytes; Polymers; Pregnancy; Rats; Rats, Sprague-Dawley; Tyrosine

2008
Ab initio studies of receptor interactions with AMPA ((S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid) and kainic acid (2S-(2 alpha, 3 beta, 4 beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid.
    Journal of molecular modeling, 2009, Volume: 15, Issue:9

    Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Behavior; Brain; Excitatory Amino Acid Agonists; Humans; Kainic Acid; Molecular Sequence Data; Mutation; Proline; Quantum Theory; Receptors, AMPA; Thermodynamics; Tyrosine

2009
FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jun-24, Volume: 29, Issue:25

    Topics: Animals; Blotting, Western; Cell Count; Cell Culture Techniques; Cell Death; Computational Biology; Disease Models, Animal; Drosophila; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Fluorescence; Forkhead Box Protein O3; Forkhead Transcription Factors; Immunohistochemistry; Kainic Acid; Mice; Mice, Inbred C57BL; Motor Neuron Disease; Motor Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Tyrosine

2009
Fcgamma receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection.
    Neuroscience, 2010, Mar-31, Volume: 166, Issue:3

    Topics: Animals; Antibodies, Neutralizing; Cell Death; Cyclooxygenase 2; Hippocampus; Kainic Acid; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Microglia; Neurons; Nitric Oxide Synthase Type II; Oxidative Stress; Pyramidal Cells; Receptors, IgG; Tissue Plasminogen Activator; Tyrosine

2010
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine

2013
Temporal and spatial increase of reactive nitrogen species in the kainate model of temporal lobe epilepsy.
    Neurobiology of disease, 2014, Volume: 64

    Topics: Animals; Astrocytes; Coenzyme A; Epilepsy, Temporal Lobe; Glutathione; Glutathione Disulfide; Hippocampus; Kainic Acid; Male; Mitochondria; Neurons; Nitric Oxide; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Seizures; Severity of Illness Index; Time Factors; Tyrosine

2014
Metallothionein expression in the rat brain following KA and PTZ treatment.
    Environmental toxicology and pharmacology, 2015, Volume: 40, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Epilepsy; Kainic Acid; Male; Metallothionein; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Tyrosine

2015
Neuroprotective effects of a protein tyrosine phosphatase inhibitor against hippocampal excitotoxic injury.
    Brain research, 2019, 09-15, Volume: 1719

    Topics: Animals; Brain; Cell Death; Cell Survival; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Temporal Lobe; Tyrosine; Vanadates

2019