tyrosine has been researched along with indomethacin in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (32.00) | 18.7374 |
| 1990's | 20 (40.00) | 18.2507 |
| 2000's | 9 (18.00) | 29.6817 |
| 2010's | 4 (8.00) | 24.3611 |
| 2020's | 1 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bundgaard, H; Nielsen, NM | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, X; Darshini, N; Leng, J; Mallesha, N; Qin, HL; Rakesh, KP; Shubhavathi, T; Vivek, HK | 1 |
| Roosdorp, N; Sjöholm, I; Wänn, B | 1 |
| Arteaga, CL; Awad, JA; Boland, CR; Coffey, RJ; Kraus, ER; Nanney, LB; Polk, WH; Romano, M; Wargovich, MJ | 1 |
| Curtis, JF; DeGray, JA; Eling, TE; Lassmann, G; Marnett, LJ; Mason, RP; Odenwaller, R | 1 |
| Fischer, JE; Hasselgren, PO; James, JH; Zamir, O | 1 |
| DeWitt, DL; Kulmacz, RJ; Shimokawa, T; Smith, WL | 1 |
| Kulmacz, RJ; Palmer, G; Ren, Y; Tsai, AL | 1 |
| Evans, J; Shaw, KP; Vernon, LP; Wang, YD | 1 |
| Fischer, JE; Hasselgren, PO; Hummel, RP; James, JH; Ogle, CK; Warner, BW | 1 |
| Turinsky, J | 1 |
| Barcelli, UO; Bjornson, HS; Edwards, LL; Fischer, JE; Freund, HR; Gallon, LS; James, JH; Joffe, SN; LaFrance, R | 1 |
| Goodman, MN; Lowell, BB; Ruderman, NB | 1 |
| Loegering, DJ; Turinsky, J | 1 |
| Odessey, R | 1 |
| Ono, T; Tsurufuji, S | 1 |
| Skidmore, IF; Whitehouse, MW | 1 |
| Hamaguchi, Y; Ito, M; Suzuki, Y; Yamagami, I | 1 |
| Brown, JH; Mackey, HK | 1 |
| Cornelissen, G; Mörsdorf, K | 1 |
| Bucciarelli de Simone, A; Rubio, MC | 1 |
| Cifarelli, A; Setnikar, I; Vidal y Plana, RR | 1 |
| Earp, HS; Huckle, WR | 1 |
| Brugge, JS; Cunningham, M; Ginsberg, MH; Haimovich, B; Lipfert, L; Parsons, JT; Shattil, SJ | 1 |
| Adachi, T; Nakamura, T; Nakashima, S; Nozawa, Y; Saji, S | 1 |
| Chen, F; Demers, LM; Gaydos, LJ; Kuhn, DC; Sun, SC | 1 |
| Kobuchi, H; Kurashige, T; Minakami, K; Miyahara, M; Utsumi, K; Watanabe, Y | 1 |
| de Médicis, R; Gaudry, M; Lussier, A; Naccache, PH; Poubelle, PE; Roberge, CJ | 1 |
| Kulmacz, RJ; Palmer, G; Tsai, A | 1 |
| Hsi, LC; Kulmacz, RJ; Palmer, G; Smith, WL; Tsai, A | 1 |
| Pawlowski, JE; Penning, TM | 1 |
| Curtis, J; Eling, TE; Lassmann, G; Liermann, B; Mason, RP | 1 |
| Murai, A; Nakahata, N; Nakamura, H; Ohizumi, Y; Rho, MC | 2 |
| Callan, OH; Mak, AY; Scarafia, LE; So, OY; Swinney, DC | 1 |
| Crews, BC; Eling, TE; Goodwin, DC; Gunther, MR; Hsi, LC; Marnett, LJ; Mason, RP | 1 |
| Bachschmid, M; Zou, MH | 1 |
| Babcock, GT; Dorlet, P; Gerfen, GJ; Seibold, SA; Smith, WL; Tsai, AL; Un, S | 1 |
| Ehring, GR; Jones, MK; Kawanaka, H; Pai, R; Szabó, IL; Tarnawski, AS | 1 |
| Hoshino, T; Mima, S; Mizushima, T; Tomisato, W; Tsuchiya, T; Tsutsumi, S | 1 |
| Chen, J; Chen, Q; Jiang, H; Shen, J; Shen, X; Sun, T | 1 |
| Breyer, RM; Hata, AN; Lybrand, TP | 1 |
| Bubolz, AH; Gutterman, DD; Liu, Y; Newman, DK; Newman, PJ; Shi, Y | 1 |
| Arruebo, MP; Grasa, L; Murillo, MD; Plaza, MA | 1 |
| Cetin, A; Kayişli, UA; Ozdem, SS; Oztürk, OH; Sentürk, UK; Uysal, N; Yeşilkaya, A | 1 |
| Chen, YJ; Li, J; Quilley, J | 1 |
| Amagase, K; Hashimura, H; Kato, S; Kawahara, R; Takeuchi, K; Yasuda, M | 1 |
| Bidmon, HJ; Brück, J; Görg, B; Häussinger, D; Keitel, V; Kircheis, G; Qvartskhava, N; Zemtsova, I | 1 |
| Cheung, HYF; Garcia, Á; Heemskerk, JWM; Moran, LA; Sickmann, A; Watson, SP | 1 |
50 other study(ies) available for tyrosine and indomethacin
| Article | Year |
|---|---|
Esters of N,N-disubstituted 2-hydroxyacetamides as a novel highly biolabile prodrug type for carboxylic acid agents.
Topics: Acetamides; Biotransformation; Carboxylic Acids; Half-Life; Humans; Indicators and Reagents; Kinetics; Structure-Activity Relationship | 1987 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis and molecular docking studies of xanthone attached amino acids as potential antimicrobial and anti-inflammatory agents.
Topics: | 2017 |
Correlation between arginyl residue modification and benzodiazepine binding to human serum albumin.
Topics: Arginine; Bilirubin; Binding Sites; Cyclohexanones; Diazepam; Humans; Imidazoles; Indomethacin; Lysine; Phenylbutazone; Protein Binding; Protein Conformation; Serum Albumin; Tyrosine | 1977 |
Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo.
Topics: Animals; Aspirin; Dinoprostone; Ethanol; Ethylmaleimide; Gastric Mucins; Gastric Mucosa; Image Processing, Computer-Assisted; Indomethacin; Microscopy, Electron, Scanning; Necrosis; Ornithine Decarboxylase; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases; Tyrosine | 1992 |
Electron spin resonance investigation of tyrosyl radicals of prostaglandin H synthase. Relation to enzyme catalysis.
Topics: Alkenes; Animals; Arachidonic Acid; Catalysis; Chromatography, High Pressure Liquid; Eicosanoids; Electron Spin Resonance Spectroscopy; Free Radicals; Indomethacin; Male; Microwaves; Peroxides; Phenol; Phenols; Prostaglandin-Endoperoxide Synthases; Protoporphyrins; Sheep; Tyrosine | 1991 |
Prostaglandin E2 does not regulate total or myofibrillar protein breakdown in incubated skeletal muscle from normal or septic rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Dinoprostone; In Vitro Techniques; Indomethacin; Male; Methylhistidines; Muscle Proteins; Rats; Rats, Inbred Strains; Sepsis; Tyrosine | 1990 |
Tyrosine 385 of prostaglandin endoperoxide synthase is required for cyclooxygenase catalysis.
Topics: Animals; Arachidonic Acids; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Indomethacin; Microsomes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Sheep; Tetranitromethane; Transfection; Tyrosine | 1990 |
Prostaglandin H synthase: spectroscopic studies of the interaction with hydroperoxides and with indomethacin.
Topics: Cyclooxygenase Inhibitors; Electron Spin Resonance Spectroscopy; Free Radicals; Indomethacin; Leukotrienes; Lipid Peroxides; Peroxides; Prostaglandin-Endoperoxide Synthases; Tetranitromethane; Tyrosine | 1990 |
Cellular responses to Pyrularia thionin are mediated by Ca2+ influx and phospholipase A2 activation and are inhibited by thionin tyrosine iodination.
Topics: Animals; Antimicrobial Cationic Peptides; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Cell Survival; Cells, Cultured; Dexamethasone; Enzyme Activation; Hemolysis; Humans; Indomethacin; Iodides; Membrane Potentials; Mice; Muscles; Phospholipases; Phospholipases A; Phospholipases A2; Plant Proteins; Quinacrine; Seeds; Tyrosine | 1989 |
Further evidence that accelerated muscle protein breakdown during sepsis is not mediated by prostaglandin E2.
Topics: Animals; Bacterial Infections; Dinoprostone; Indomethacin; Male; Muscle Proteins; Muscles; Prostaglandins E; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Phospholipids, prostaglandin E2, and proteolysis in denervated muscle.
Topics: Animals; Aspirin; Cardiolipins; Cycloheximide; Dinoprostone; Indomethacin; Lysophosphatidylcholines; Male; Muscle Denervation; Muscle Proteins; Muscles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Sphingomyelins; Tyrosine | 1986 |
The effect of indomethacin on muscle and liver protein synthesis and on whole-body protein degradation during abdominal sepsis in the rat.
Topics: Abdomen; Amino Acids; Animals; Carbon Radioisotopes; Dinoprostone; Indomethacin; Infections; Kinetics; Liver; Male; Muscles; Prostaglandins E; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
Regulation of myofibrillar protein degradation in rat skeletal muscle during brief and prolonged starvation.
Topics: 3-Hydroxybutyric Acid; Adrenalectomy; Amino Acids; Animals; Body Weight; Cycloheximide; Epinephrine; Glucagon; Hydroxybutyrates; Indomethacin; Insulin; Male; Methylhistidines; Muscle Proteins; Muscles; Rats; Rats, Inbred Strains; Starvation; Time Factors; Tyrosine; Urea | 1986 |
Prostaglandin E2 and muscle protein turnover in Pseudomonas aeruginosa sepsis.
Topics: Animals; Aspirin; Cycloheximide; Dinoprostone; Indomethacin; Male; Muscle Proteins; Muscles; Prostaglandins E; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Effect of inhibitors of proteolysis and arachidonic acid metabolism on burn-induced protein breakdown.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Hindlimb; Ibuprofen; In Vitro Techniques; Indomethacin; Leupeptins; Lysosomes; Muscles; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Proteins; Quinacrine; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
The mode of action of hydrocortisone on the protein metabolism in rat carrageenin granuloma.
Topics: Animals; Betamethasone; Carrageenan; Cycloheximide; Granuloma; Hydrocortisone; In Vitro Techniques; Indomethacin; Male; Perchlorates; Phenylbutazone; Proteins; Puromycin; Rats; Sodium Salicylate; Tritium; Tyrosine | 1970 |
Concerning the regulation of some diverse biochemical reactions underlying the inflammatory response by salicylic acid, phenylbutazone and other acidic antirheumatic drugs.
Topics: Acetates; Adrenal Medulla; Animals; Anti-Inflammatory Agents; Benzoates; Cattle; Chloroquine; Chymotrypsin; Dopa Decarboxylase; Flufenamic Acid; In Vitro Techniques; Indomethacin; Kinetics; Mefenamic Acid; ortho-Aminobenzoates; Phenylacetates; Phenylbutazone; Salicylates; Serotonin; Succinates; Tyrosine | 1966 |
[Biochemical studies on action mechnism of a new anti-inflammatory agent, naproxen (1). Effects of naproxen on changes in connective tissue components due to inflammation].
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Connective Tissue; Dimethylamines; Female; Granuloma; Hexosamines; Hydroxyproline; Indazoles; Indomethacin; Inflammation; Methyl Ethers; Naphthalenes; Prednisolone; Propionates; Rats; Sialic Acids; Time Factors; Tyrosine; Uronic Acids | 1974 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
[Contribution to the evaluation of anti-inflammatory agents in vitro].
Topics: Animals; Anti-Inflammatory Agents; Cortisone; Esterases; Flufenamic Acid; Indomethacin; Inflammation; Male; Mefenamic Acid; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Rats; Salicylates; Tyrosine | 1966 |
Differential effects of prostaglandins E1 and E2 on tyrosine hydroxylase activity of the superior cervical ganglion of the cat.
Topics: Animals; Cats; Cyclic AMP; Dose-Response Relationship, Drug; Female; Ganglia, Sympathetic; Indomethacin; Kinetics; Male; Prostaglandins E; Tyrosine; Tyrosine 3-Monooxygenase | 1980 |
Mechanism of smooth muscle relaxation by tiropramide.
Topics: Animals; Calcium; Colon; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Phosphodiesterase Inhibitors; Prostaglandins E; Rabbits; Tyrosine | 1981 |
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols.
Topics: Acetylcysteine; Angiotensin II; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Drug Synergism; Egtazic Acid; Enzyme Activation; Flavonoids; Flavonols; Indomethacin; Liver; Masoprocol; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Rats; Tyrosine; Vanadates | 1994 |
Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Alprostadil; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cytoplasm; Egtazic Acid; Epinephrine; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Indoles; Indomethacin; Maleimides; Models, Biological; Phosphorylation; Phosphotyrosine; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Thromboxane A2; Tyrosine; Vasodilator Agents | 1994 |
Roles of prostaglandin production and mitogen-activated protein kinase activation in hepatocyte growth factor-mediated rat hepatocyte proliferation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; DNA; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Indomethacin; Kinetics; Liver; Male; Phospholipases A; Phospholipases A2; Phosphotyrosine; Prostaglandins; Rats; Rats, Wistar; Tyrosine | 1995 |
Dependence and reversal of nitric oxide production on NF-kappa B in silica and lipopolysaccharide-induced macrophages.
Topics: Acetylcysteine; Alkaloids; Animals; Arginine; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Molecular Sequence Data; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotide Probes; omega-N-Methylarginine; Protein Kinase C; Silicon Dioxide; Staurosporine; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine | 1995 |
Effect of indomethacin and aspirin on the TNF-alpha-induced priming and protein tyrosyl phosphorylation of human neutrophils.
Topics: Animals; Aspirin; Azides; Electrophoresis, Polyacrylamide Gel; Granulocyte Colony-Stimulating Factor; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sodium Azide; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine | 1993 |
Crystal-induced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine.
Topics: Blood Proteins; Calcium Pyrophosphate; Colchicine; Crystallization; Demecolcine; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Nocodazole; Phenylbutazone; Phosphorylation; Phosphotyrosine; Tyrosine; Uric Acid; Vinblastine | 1993 |
Spectroscopic evidence for reaction of prostaglandin H synthase-1 tyrosyl radical with arachidonic acid.
Topics: Animals; Arachidonic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Tyrosine | 1995 |
Characterization of the tyrosyl radicals in ovine prostaglandin H synthase-1 by isotope replacement and site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Electron Spin Resonance Spectroscopy; Free Radicals; Gene Expression; Hydrogen Peroxide; Indomethacin; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sheep; Substrate Specificity; Transfection; Tyrosine | 1994 |
Overexpression and mutagenesis of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Role of cysteines and tyrosines in catalysis.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Base Sequence; Catalysis; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Indomethacin; Kinetics; Liver; Molecular Sequence Data; Mutagenesis; Rats; Tyrosine | 1994 |
ESR studies on reactivity of protein-derived tyrosyl radicals formed by prostaglandin H synthase and ribonucleotide reductase.
Topics: Animals; Anisoles; Carcinoma, Ehrlich Tumor; Cyclooxygenase Inhibitors; Electron Spin Resonance Spectroscopy; Eugenol; Free Radicals; Hydroxyurea; Indoleacetic Acids; Indomethacin; Kinetics; Male; Mice; Prostaglandin-Endoperoxide Synthases; Ribonucleotide Reductases; Seminal Vesicles; Sheep; Tyrosine | 1993 |
Tyrphostin 23 blocks phosphorylation of p42 but not p38 mitogen-activated protein kinase by zooxanthellatoxin-A.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Enzyme Inhibitors; Genistein; In Vitro Techniques; Indomethacin; Isoflavones; Male; Marine Toxins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Polyenes; Precipitin Tests; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Tyrphostins | 1997 |
Involvement of phospholipase C-gamma2 in activation of mitogen-activated protein kinase and phospholipase A2 by zooxanthellatoxin-A in rabbit platelets.
Topics: Animals; Arachidonic Acid; Blood Platelets; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Genistein; Indomethacin; Isoflavones; Male; Naphthalenes; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phosphorylation; Polyenes; Rabbits; Staurosporine; Type C Phospholipases; Tyrosine | 1997 |
The dynamics of prostaglandin H synthases. Studies with prostaglandin h synthase 2 Y355F unmask mechanisms of time-dependent inhibition and allosteric activation.
Topics: Allosteric Regulation; Arachidonic Acid; Binding Sites; Catalysis; Cyclooxygenase Inhibitors; Enzyme Activation; Hydrogen Bonding; Indomethacin; Kinetics; Models, Molecular; Molecular Structure; Oxygen; Prostaglandin-Endoperoxide Synthases; Thermodynamics; Tyrosine | 1998 |
Nitric oxide trapping of tyrosyl radicals generated during prostaglandin endoperoxide synthase turnover. Detection of the radical derivative of tyrosine 385.
Topics: Amino Acid Sequence; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Electron Spin Resonance Spectroscopy; Free Radicals; Indomethacin; Isoenzymes; Models, Chemical; Molecular Sequence Data; Nitric Oxide; Peptide Fragments; Peptide Mapping; Prostaglandin-Endoperoxide Synthases; Tetranitromethane; Tyrosine | 1998 |
Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Coronary Vasospasm; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Hydrazines; Hypoxia; In Vitro Techniques; Indomethacin; Intramolecular Oxidoreductases; Nitrates; Oxygen; Tyrosine | 1999 |
High-field EPR study of tyrosyl radicals in prostaglandin H(2) synthase-1.
Topics: Animals; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Bonding; In Vitro Techniques; Indomethacin; Isoenzymes; Models, Molecular; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Sheep; Static Electricity; Tyrosine | 2002 |
Indomethacin delays gastric restitution: association with the inhibition of focal adhesion kinase and tensin phosphorylation and reduced actin stress fibers.
Topics: Actins; Animals; Apoptosis; Caspase 3; Caspases; Cell Death; Cell Line; Cell Movement; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastric Mucosa; Humans; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Indomethacin; Male; Microfilament Proteins; Mitomycin; Necrosis; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Stomach; Stress Fibers; Tensins; Time Factors; Tyrosine | 2002 |
Molecular mechanism of adaptive cytoprotection induced by ethanol in human gastric cells.
Topics: Cell Line, Tumor; Culture Media; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytoprotection; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Genistein; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Processing, Post-Translational; Stomach; Time Factors; Tyrosine | 2003 |
A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.
Topics: alpha-Galactosidase; Anilides; Cells, Cultured; Chromans; CREB-Binding Protein; Drug Evaluation, Preclinical; Genes, Reporter; Indomethacin; Ligands; Nuclear Proteins; Oxazoles; Pioglitazone; PPAR gamma; Prostaglandin D2; Protein Binding; Rosiglitazone; Thiazolidinediones; Trans-Activators; Troglitazone; Two-Hybrid System Techniques; Tyrosine; Yeasts | 2004 |
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamic Acid; Humans; Hypersensitivity; Indomethacin; Inflammation; Kinetics; Ligands; Mice; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Tyrosine | 2005 |
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.
Topics: Animals; Azoles; Biological Factors; Coronary Vessels; Gene Deletion; Hydrogen Peroxide; Indomethacin; Isoindoles; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organoselenium Compounds; Peroxynitrous Acid; Platelet Endothelial Cell Adhesion Molecule-1; Prostaglandins; Tyrosine; Vasodilation | 2006 |
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro.
Topics: Animals; Calcium; Carbachol; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Estrenes; Genistein; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Rabbits; Tyrosine; Tyrphostins; Vanadates; Verapamil | 2006 |
Plasma levels of nitrites, PGF1alpha, and nitrotyrosine in LPS-treated rats: functional and histochemical implications in aorta.
Topics: Animals; Aorta; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrites; Phenylephrine; Prostaglandins F; Rats; Rats, Wistar; Tyrosine; Vasoconstriction | 2006 |
Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress.
Topics: Aldehyde Reductase; Animals; Antioxidants; Arachidonic Acid; Benzothiazoles; Cyclic N-Oxides; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Enzyme Induction; Enzyme Inhibitors; Fenofibrate; Hydroxyeicosatetraenoic Acids; Hypoglycemic Agents; Indomethacin; Insulin; Kidney; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Perfusion; Phthalazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Spin Labels; Tyrosine | 2008 |
Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzamides; Bridged Bicyclo Compounds; Gene Expression Regulation, Enzymologic; Indomethacin; Intestine, Small; Macrophages; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Nitric Oxide Synthase Type II; Peroxidase; Receptors, Nicotinic; RNA, Messenger; Tyrosine; Ulcer | 2011 |
Locomotor impairment and cerebrocortical oxidative stress in portal vein ligated rats in vivo.
Topics: Animals; Cerebral Cortex; Cytokines; Hepatic Encephalopathy; Hyperammonemia; Indomethacin; Ligation; Male; Microglia; Motor Activity; Nitric Oxide Synthase Type II; Oxidative Stress; Portal Vein; Rats; Rats, Wistar; RNA, Messenger; Tyrosine | 2011 |
Inhibition of Src but not Syk causes weak reversal of GPVI-mediated platelet aggregation measured by light transmission aggregometry.
Topics: Agammaglobulinaemia Tyrosine Kinase; Apyrase; Blood Platelets; Collagen; Eptifibatide; Fluorescein-5-isothiocyanate; Humans; Indomethacin; Intracellular Signaling Peptides and Proteins; Lectins, C-Type; Ligands; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; src-Family Kinases; Syk Kinase; Tyrosine | 2022 |