tyrosine has been researched along with hydroxyl radical in 127 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (7.09) | 18.7374 |
| 1990's | 46 (36.22) | 18.2507 |
| 2000's | 50 (39.37) | 29.6817 |
| 2010's | 18 (14.17) | 24.3611 |
| 2020's | 4 (3.15) | 2.80 |
| Authors | Studies |
|---|---|
| Koppenol, WH; Maskos, Z; Rush, JD | 1 |
| Dizdaroglu, M; Nackerdien, Z; Olinski, R | 1 |
| Bergtold, DS; Karam, LR; Simic, MG | 1 |
| Vissers, MC; Winterbourn, CC | 1 |
| Ayling, JE; Bailey, SW; Dillard, SB | 1 |
| Dizdaroglu, M; Gajewski, E | 1 |
| Karam, LR; Simic, MG | 2 |
| Dizdaroglu, M; Gajewski, E; Margolis, SA; Reddy, P | 1 |
| Fagerheim, I; Grootveld, M; Halliwell, B; Kaur, H; Puppo, A | 1 |
| Coxon, B; Dizdaroglu, M; Gajewski, E; Margolis, SA | 1 |
| Bobrowski, K; Lubis, R | 1 |
| Davies, KJ; Delsignore, ME; Lin, SW | 1 |
| Davies, KJ; Delsignore, ME | 1 |
| Dorris, ML; Magnusson, RP; Taurog, A | 1 |
| Kelly, FJ; Lubec, G | 1 |
| Beal, MF; Chan, PH; Epstein, CJ; Ferrante, RJ; Henshaw, R; Kowall, NW; Matthews, RT; Schulz, JB | 1 |
| Cross, CE; Eiserich, JP; Halliwell, B; Van der Vliet, A | 1 |
| Van der Walt, BJ; Van Zyl, JM | 1 |
| Beckman, JS | 2 |
| Schraermeyer, U | 1 |
| Godoy, J; Silva, E | 1 |
| Kim, JI; Kohno, T; Kudo, Y; Ogura, A; Sato, K; Takahashi, M | 1 |
| Franzini, E; Hakim, J; Pasquier, C; Sellak, H | 1 |
| Colomb, M; Drouet, C; Gabert, F; Pernollet, M; Villiers, C | 1 |
| Cross, CE; Halliwell, B; Kaur, H; O'Neill, CA; van der Vliet, A | 1 |
| Bolli, R; Halliwell, B; Kaur, H; Li, XY; Sun, JZ | 1 |
| Fujimoto, S; Kawakami, N; Ohara, A | 1 |
| Bauer, G; Denk, W; Hayn, M; Lubec, B | 1 |
| Frischer, T; Haschke, N; Kühr, J; Lubec, G; Meinert, R; Pullwitt, A; Studnicka, M | 1 |
| Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Pennathur, S; Rasmussen, JE | 1 |
| Blake, DR; Edmonds, SE; Halliwell, B; Kaur, H | 1 |
| Halliwell, B; Whiteman, M | 1 |
| Duong, DK; Miller, AF; Sorkin, DL | 1 |
| Kerjaschki, D; Riedle, B | 1 |
| Ayata, C; Ayata, G; Beal, MF; Christie, RH; Endres, M; Ferrante, RJ; Hara, H; Huang, PL; Hyman, BT; Kim, A; Matthews, RT; Moskowitz, MA; Waeber, C | 1 |
| Hayde, M; Lubec, G; Menzel, D; Pollak, A; Widness, JA | 1 |
| Heinecke, JW; Holloszy, JO; Leeuwenburgh, C; Sohal, RS; Wagner, P | 1 |
| Antonini, G; Battistoni, A; Board, PG; Caccuri, AM; Lo Bello, M; Nicotra, M; Parker, MW; Ricci, G | 1 |
| Hansen, P; Heinecke, JW; Holloszy, JO; Leeuwenburgh, C; Shaish, A | 1 |
| Kotovych, G; McClung, RE; Nakashima, TT | 1 |
| Anderson, W; Dimon-Gadal, S; Evain-Brion, D; Gerbaud, P; Keryer, G; Raynaud, F | 1 |
| Malagon, I | 1 |
| Cohen, G; Dembiec-Cohen, D; Yakushin, S | 1 |
| Acworth, IN; Beal, MF; Bogdanov, MB; McCabe, DR | 1 |
| Amacker, M; Faraj, A; Gosselin, G; Hübscher, U; Imbach, JL; Maga, G; Mathé, C; Sommadossi, JP; Spadari, S | 1 |
| Gudelsky, GA; Shankaran, M; Yamamoto, BK | 1 |
| Hansen, PA; Heinecke, JW; Holloszy, JO; Leeuwenburgh, C | 1 |
| Blandini, F; Desideri, S; Godi, L; Mancini, F; Martignoni, E; Nappi, G; Pacchetti, C | 1 |
| Baker, C; Evans, TW; Gutteridge, JM; Lamb, NJ; Quinlan, GJ | 1 |
| Blandini, F; di Jeso, F; Martignoni, E; Nappi, G; Ricotti, R | 1 |
| Fujimoto, S; Hayakawa, T; Kawakami, N; Shimohama, S | 1 |
| Kimura, M; Kuwano, E; Miyamoto, A; Tanaka, I; Usui, M; Yamada, N; Yamasaki, N | 1 |
| Halliwell, B; Jones, AD; Longhurst, JC; Reddy, S | 1 |
| Anderson, VE; Chen, YH; Goshe, MB | 1 |
| Audette, M; Blouquit, Y; Houée-Levin, C | 1 |
| Hirouchi, M; Itoh, Y; Oka, M; Ukai, Y | 1 |
| Augusto, O; Bonini, MG; Santos, CX | 1 |
| Grüning, C; Rehder, D | 1 |
| Li, Y; Wavak, D; Wolf, ME; Xue, CJ | 1 |
| Franceschi, C; Galeazzi, L; Giunta, S; Ronchi, P; Valli, B | 1 |
| Ambrosio, G; Biondi, R; Paolocci, N; Rossi, R; Xia, Y; Zweier, JL | 1 |
| Ding, Y; Gonick, HC; Liang, K; Vaziri, ND; Wei, L | 1 |
| Heinecke, JW; Leeuwenburgh, C; Litwak, KN; Pennathur, S; Wagner, JD | 1 |
| Bartosz, G; Grzelak, A; Rychlik, B | 1 |
| Feix, J; Hogg, N; Joseph, J; Kalyanaraman, B; Zhang, H | 1 |
| Bauer, JA; Carnes, CA; McCarthy, PM; Mihm, MJ; Reiser, PJ; Van Wagoner, DR; Yu, F | 1 |
| Joseph, J; Kalyanaraman, B; Zhang, H | 1 |
| Chen, CL; Chi, CW; Liu, TY | 1 |
| Dubinina, EE; Gavrovskaya, SV; Kovrugina, SV; Kuzmich, EV; Leonova, NV; Morozova, MG; Smirnova, TA | 1 |
| Huycke, MM; Moore, DR | 1 |
| Choi, JJ; Kim, HC; Kim, WK; Ko, KH; Kong, MY; Lee, SJ | 1 |
| Kang, JH; Kim, KS | 1 |
| Grossi, L | 1 |
| PEARLMANN, GE | 1 |
| Carlson, S; Kinzer, JA; Li, M; Perpall, HJ | 1 |
| Schöneich, C | 1 |
| Barrera, D; Castro, L; Chirino, YI; Hernández-Pando, R; Macías-Ruvalcaba, NA; Maldonado, PD; Medina-Campos, ON; Pedraza-Chaverrí, J; Salcedo, MI | 1 |
| Creed, J; Greeley, W; Pastuszko, A; Schears, G; Schultz, S; Wilson, DF; Zaitseva, T | 1 |
| Koppenol, WH; Nauser, T; Pelling, J; Schöneich, C | 1 |
| Anderson, VE; Nukuna, BN; Sun, G | 1 |
| Cacciatore, I; Cocco, A; Costa, M; Fontana, M; Lucente, G; Pecci, L; Pinnen, F | 1 |
| Endo, T; Iguchi, F; Ito, J; Kim, TS; Lee, JE; Lee, SH; Nakagawa, T; Shiga, A | 1 |
| Byun, J; Danda, R; Heinecke, JW; Heller, JI; Ido, Y; Pennathur, S; Pergola, P; Williamson, JR | 1 |
| Bian, ZY; Du, JO; Guo, XQ; Zhao, YB | 1 |
| Kó Szegi, T; Kocsis, B; Laczy, B; Markó, L; Matus, Z; Mazák, I; Mohás, M; Molnár, GA; Nagy, J; Tamaskó, M; Wagner, L; Wagner, Z; Wittmann, I | 1 |
| Biró, Z; Ludány, A; Molnár, GA; Nemes, V; Wagner, Z; Wittmann, I | 1 |
| Czapski, G; Goldstein, S; Heller, A | 1 |
| Barbar, EJ; Deeb, RS; Gross, SS; Hajjar, DP; Hao, G; Lainé, M; Qiu, JH; Resnick, B; Upmacis, RK | 1 |
| Cárdenas-Rodríguez, N; Floriano-Sánchez, E; Medina-Campos, ON; Pedraza-Chaverrí, J; Rocha, D; Sánchez-González, DJ; Villanueva, C | 1 |
| Ambrosio, G; Bettini, M; Biondi, R; Cardounel, AJ; Liebgott, T; Tritto, I; Zweier, JL | 1 |
| Auten, RL; Li, Y; Liao, L; Liu, X; Luo, X; Ning, Q; Tanswell, AK; Wang, A; Wang, W; Wei, W | 1 |
| Changchien, L; Honts, JE; Hyatt, DC; Maley, F; Maley, GF; Montfort, WR; Roberts, SA | 1 |
| Dong, JC; Li, YM; Shi, WQ; Zhao, YF | 1 |
| Buré, C; Cadene, M; Davidkova, M; Gillard, N; Goffinont, S; Maurizot, JC; Spotheim-Maurizot, M | 1 |
| Rahbar, S | 1 |
| Alvarez, MN; Folkes, L; Peluffo, G; Radi, R; Wardman, P | 1 |
| Dennis, DM; Glushakov, AV; Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Yarotskyy, V | 1 |
| Chen, SC; Chen, WC | 1 |
| Kavitha, R; Nagalakshmi, V; Rajamohan, R; Ramesh, D; Shanmugam, M; Stalin, T | 1 |
| Dedon, PC; Deen, WM; Lim, CH | 1 |
| Agard, DA; Ho, BK | 1 |
| Gunaydin, H; Houk, KN | 1 |
| Puntarulo, S; Rousseau, I | 1 |
| Liu, R; Sun, F; Tian, Y; Wang, M; Zhang, P; Zong, W | 1 |
| Bigelow, DJ; Camp, DG; Chen, B; Chin, MH; Heibeck, TH; Jacobs, JM; Monroe, ME; Petritis, BO; Pounds, JG; Qian, WJ; Schepmoes, AA; Smith, DJ; Smith, RD; Yang, F; Zhang, X | 1 |
| Ageeva, TS; Bezmenova, MA; Ivanov, VV; Petina, GV; Riazantseva, NV; Stepovaia, EA; Tetenev, FF; Zhavoronok, TV | 1 |
| Gurgul-Convey, E; Lenzen, S; Lortz, S; Mehmeti, I | 1 |
| Jia, XL; Sun, YH; Wang, WL; Wu, LS | 1 |
| Bush, AI; Gunn, AP; Roberts, BR | 1 |
| Chen, C; Hu, M; Lü, JM; Weakley, SM; Yang, Z; Yao, Q | 1 |
| Matxain, JM; Mujika, JI; Uranga, J | 1 |
| Hanaoka, K; Kamiya, K; Kondo, D; Sato, A; Shiraishi, K; Shoji, M; Yang, MY | 1 |
| Deb-Choudhury, S; Dyer, JM; Grosvenor, AJ; Plowman, JE | 1 |
| Estévez, M; Parra, V; Villaverde, A | 1 |
| Kissner, R; Koppenol, WH; Penders, J | 1 |
| Kohno, M; Niwano, Y; Tada, M | 1 |
| Bogár, L; Csontos, C; Kun, S; Miseta, A; Molnár, GA; Sélley, E; Szélig, L; Wittmann, I | 1 |
| Kostiainen, R; Kotiaho, T; Ollikainen, E; Ruokolainen, M; Sikanen, T | 1 |
| Egorova, MY; Nosareva, OL; Novitsky, VV; Ryazantseva, NV; Shakhristova, EV; Stepovaya, EA | 1 |
| Biondi, R; Bottiglieri, L; Brancorsini, S; Brillo, E; Capodicasa, E; Cretoiu, D; Egidi, MG; Gerli, S; Micu, R; Poli, G; Renzo, GCD; Suciu, N | 1 |
| Ford, B; Nomura, DK; Prasse, C; Sedlak, DL | 1 |
| Biswas, A; Chakraborty, A; Nandi, SK; Panda, AK | 1 |
| Iwahara, J; Pletka, CC; Yu, B | 1 |
| Billault, I; Duchambon, P; Gatin, A; Sicard-Roselli, C; Van der Rest, G | 1 |
| Bartesaghi, S; Folkes, LK; Radi, R; Trujillo, M; Wardman, P | 1 |
6 review(s) available for tyrosine and hydroxyl radical
| Article | Year |
|---|---|
Biomarkers of OH radical damage in vivo.
Topics: Biomarkers; DNA; Free Radicals; Hydroxides; Hydroxyl Radical; Hydroxylation; Phenylalanine; Proteins; Thymine; Thymine Nucleotides; Tyrosine | 1991 |
Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury.
Topics: Animals; Brain; Brain Injuries; Humans; Hydroxyl Radical; Nitrates; Nitric Oxide; Superoxide Dismutase; Superoxides; Tyrosine | 1994 |
Bicarbonate enhances nitration and oxidation reactions in biological systems--role of reactive oxygen and nitrogen species.
Topics: Bicarbonates; Copper; Cyclic N-Oxides; Humans; Hydrogen Peroxide; Hydroxyl Radical; Nitrates; Oxidation-Reduction; Peroxidases; Reactive Nitrogen Species; Reactive Oxygen Species; Spin Trapping; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine | 2001 |
Selective Cu2+/ascorbate-dependent oxidation of alzheimer's disease beta-amyloid peptides.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Ascorbic Acid; Copper; Histidine; Humans; Hydroxyl Radical; Hydroxylation; Oxidation-Reduction; Peptide Fragments; Tyrosine | 2004 |
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
Topics: Animals; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydroxyl Radical; Mental Disorders; Neuroprotective Agents; Phenylalanine; Synaptic Transmission; Tyrosine | 2006 |
Radiolysis Studies of Oxidation and Nitration of Tyrosine and Some Other Biological Targets by Peroxynitrite-Derived Radicals.
Topics: Free Radicals; Hydroxyl Radical; Oxidation-Reduction; Peroxynitrous Acid; Tyrosine | 2022 |
2 trial(s) available for tyrosine and hydroxyl radical
| Article | Year |
|---|---|
Peripheral markers of oxidative stress in Parkinson's disease. The role of L-DOPA.
Topics: Antiparkinson Agents; Biomarkers; Blood Platelets; Dopamine; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Levodopa; Linear Models; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Sodium Salicylate; Superoxide Dismutase; Tyrosine | 1999 |
Determination of hydroxyl free radical formation in human platelets using high-performance liquid chromatography with electrochemical detection.
Topics: Adult; Antiparkinson Agents; Blood Platelets; Chromatography, High Pressure Liquid; Electrochemistry; Female; Humans; Hydroxybenzoates; Hydroxyl Radical; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine | 1999 |
119 other study(ies) available for tyrosine and hydroxyl radical
| Article | Year |
|---|---|
The hydroxylation of phenylalanine and tyrosine: a comparison with salicylate and tryptophan.
Topics: Chelating Agents; Dihydroxyphenylalanine; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Iron; Kinetics; Macromolecular Substances; Oxidation-Reduction; Phenylalanine; Pulse Radiolysis; Salicylates; Salicylic Acid; Tryptophan; Tyrosine | 1992 |
DNA-protein cross-linking between thymine and tyrosine in chromatin of gamma-irradiated or H2O2-treated cultured human cells.
Topics: Cell Line; Chromatin; Cross-Linking Reagents; DNA, Neoplasm; Dose-Response Relationship, Radiation; Free Radicals; Gamma Rays; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasm Proteins; Thymine; Tyrosine | 1992 |
Oxidative damage to fibronectin. II. The effect of H2O2 and the hydroxyl radical.
Topics: Ascorbic Acid; Cobalt Radioisotopes; Cross-Linking Reagents; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Fibronectins; Fluorescence; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Leukocyte Elastase; Mannitol; Molecular Weight; Oxidation-Reduction; Pancreatic Elastase; Tryptophan; Tyrosine | 1991 |
Role of C6 chirality of tetrahydropterin cofactor in catalysis and regulation of tyrosine and phenylalanine hydroxylases.
Topics: Animals; Binding, Competitive; Catalysis; Hydroxides; Hydroxyl Radical; Isomerism; Kinetics; Phenylalanine Hydroxylase; Phosphorylation; Pterins; Rats; Tyrosine; Tyrosine 3-Monooxygenase | 1991 |
Hydroxyl radical induced cross-linking of cytosine and tyrosine in nucleohistone.
Topics: Animals; Cattle; Cross-Linking Reagents; Cytosine; DNA; Gamma Rays; Gas Chromatography-Mass Spectrometry; Histones; Hydroxides; Hydroxyl Radical; Protein Binding; Thymus Gland; Tyrosine | 1990 |
Formation of ortho-tyrosine by radiation and organic solvents in chicken tissue.
Topics: Animals; Cattle; Chickens; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Free Radicals; Hydroxides; Hydroxyl Radical; Mass Spectrometry; Muscles; Phenylalanine; Solvents; Tyrosine | 1990 |
Structure of a hydroxyl radical induced DNA-protein cross-link involving thymine and tyrosine in nucleohistone.
Topics: Animals; Binding Sites; Cattle; Cross-Linking Reagents; DNA; Gas Chromatography-Mass Spectrometry; Histones; Hydroxides; Hydroxyl Radical; Molecular Structure; Proteins; Thymine; Tyrosine | 1989 |
Mechanisms of free radical chemistry and biochemistry of benzene.
Topics: Animals; Benzene; Chickens; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Models, Chemical; Muscles; Tyrosine | 1989 |
Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals: application to activated human neutrophils and to the heme protein leghemoglobin.
Topics: Chromatography, High Pressure Liquid; Free Radicals; Hemeproteins; Humans; Hydroxides; Hydroxyl Radical; Hydroxylation; Leghemoglobin; Neutrophils; Phenylalanine; Tyrosine | 1988 |
Structure of a hydroxyl radical induced cross-link of thymine and tyrosine.
Topics: Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dihydroxyphenylalanine; DNA Damage; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Biological; Thymine; Tyrosine | 1988 |
Intermolecular charge transfer involving tryptophan, tyrosine and three electron-bonded intermediates derived from methionine.
Topics: Azides; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Methionine; Oxidation-Reduction; Pulse Radiolysis; Spectrophotometry; Tryptophan; Tyrosine | 1986 |
Protein damage and degradation by oxygen radicals. II. Modification of amino acids.
Topics: Amino Acids; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Proteins; Serum Albumin, Bovine; Superoxides; Tyrosine | 1987 |
Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure.
Topics: Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Macromolecular Substances; Protein Conformation; Protein Denaturation; Proteins; Serum Albumin, Bovine; Superoxides; Tyrosine | 1987 |
Mechanisms of thyroid peroxidase- and lactoperoxidase-catalyzed reactions involving iodide.
Topics: Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iodide Peroxidase; Iodides; Kinetics; Lactoperoxidase; Peroxidases; Thyroglobulin; Tyrosine | 1984 |
Hyperoxic injury of immature guinea pig lung is mediated via hydroxyl radicals.
Topics: Animals; Animals, Newborn; Body Weight; Disease Models, Animal; Female; Guinea Pigs; Hydroxyl Radical; Hyperoxia; Lung; Lung Diseases; Lysine; Male; Oxidative Stress; Pregnancy; Survival Rate; Tyrosine | 1995 |
3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice.
Topics: Animals; Humans; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Transgenic; Neurotoxins; Nitro Compounds; Propionates; Reference Values; Superoxide Dismutase; Tyrosine | 1995 |
Modification of aromatic amino acids by reactive nitrogen species.
Topics: Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Mannitol; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrogen Oxides; Oxidants; Phenylalanine; Tyrosine | 1995 |
Apparent hydroxyl radical generation without transition metal catalysis and tyrosine nitration during oxidation of the anti-tubercular drug, isonicotinic acid hydrazide.
Topics: Catalase; Hydroxyl Radical; Isoniazid; Kinetics; Metals; Nitrates; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Thiobarbituric Acid Reactive Substances; Tyrosine | 1994 |
Transformation of albumin into melanin by hydroxyl radicals.
Topics: Electrophoresis, Polyacrylamide Gel; Hydroxyl Radical; Melanins; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1994 |
Riboflavin sensitized photooxidation of tyrosine.
Topics: Azides; Catalase; Chromatography, Gel; Deuterium; Hydrogen Peroxide; Hydroxyl Radical; Light; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Photochemistry; Riboflavin; Spectrometry, Fluorescence; Superoxide Dismutase; Superoxides; Tyrosine | 1994 |
Hydroxyl group of Tyr13 is essential for the activity of omega-conotoxin GVIA, a peptide toxin for N-type calcium channel.
Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Chickens; Hydroxyl Radical; Molecular Sequence Data; Mollusk Venoms; omega-Conotoxin GVIA; Peptides; Rats; Rats, Wistar; Tyrosine | 1994 |
Oxidative damage to lysozyme by the hydroxyl radical: comparative effects of scavengers.
Topics: Free Radical Scavengers; Hydroxyl Radical; Muramidase; Oxidation-Reduction; Tryptophan; Tyrosine | 1993 |
OH. treatment of tetanus toxin reduces its susceptibility to limited proteolysis with more efficient presentation to specific T cells.
Topics: Animals; Antigen-Presenting Cells; B-Lymphocytes; Cells, Cultured; Clone Cells; Endopeptidases; Humans; Hydroxyl Radical; Lymphocyte Activation; Oxidation-Reduction; Peptide Fragments; Spectrometry, Fluorescence; Subcellular Fractions; T-Lymphocytes; Tetanus Toxin; Tyrosine | 1993 |
Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite.
Topics: Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Serum Albumin, Bovine; Thermodynamics; Tyrosine; Uric Acid | 1994 |
Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning.
Topics: Animals; Antioxidants; Coronary Circulation; Dogs; Female; Hydroxides; Hydroxyl Radical; Hydroxylation; Male; Myocardial Infarction; Myocardium; Phenylalanine; Tyrosine | 1993 |
Formation of a hydroxyl radical by the myeloperoxidase-NADH-oxygen system.
Topics: Aerobiosis; Catalase; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Kinetics; NAD; Oxygen; Peroxidase; Phenylalanine; Superoxide Dismutase; Tyrosine | 1993 |
Brain lipid peroxidation and hydroxy radical attack following the intravenous infusion of hydrogen peroxide in an infant.
Topics: Brain; Chromatography, High Pressure Liquid; Embolism, Air; Female; Free Radicals; Humans; Hydrogen Peroxide; Hydroxyl Radical; Infant; Infusions, Intravenous; Lipid Peroxidation; Male; Malondialdehyde; Tyrosine | 1996 |
Aromatic hydroxylation in nasal lavage fluid following ambient ozone exposure.
Topics: Air Pollutants; Child, Preschool; Humans; Hydroxyl Radical; Hydroxylation; Nasal Lavage Fluid; Ozone; Reactive Oxygen Species; Regression Analysis; Respiratory Function Tests; Tobacco Smoke Pollution; Tyrosine | 1997 |
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
Topics: Animals; Aorta; Arteriosclerosis; Cattle; Copper; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyl Radical; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine | 1997 |
Hydroxyl radical generation by rheumatoid blood and knee joint synovial fluid.
Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Knee Joint; Phenylalanine; Synovial Fluid; Tyrosine | 1996 |
Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers.
Topics: alpha 1-Antitrypsin; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Nitrates; Thiourea; Tyrosine | 1997 |
Mutation of tyrosine 34 to phenylalanine eliminates the active site pK of reduced iron-containing superoxide dismutase.
Topics: Binding Sites; Electrochemistry; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyl Radical; Iron; Magnetic Resonance Spectroscopy; Mutation; Oxidation-Reduction; Phenylalanine; Superoxide Dismutase; Tyrosine | 1997 |
Reactive oxygen species cause direct damage of Engelbreth-Holm-Swarm matrix.
Topics: Animals; Biopolymers; Collagen; Cross-Linking Reagents; Dimerization; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Hydrogen Peroxide; Hydroxyl Radical; Iron; Laminin; Membrane Glycoproteins; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidation-Reduction; Reactive Oxygen Species; Tyrosine; Xanthine Oxidase | 1997 |
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Binding Sites; Corpus Striatum; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1997 |
Hydroxyl radical generation in oxygen-treated infants.
Topics: Apgar Score; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Infant, Newborn; Infant, Newborn, Diseases; Oxygen; Oxygen Inhalation Therapy; Phenylalanine; Regression Analysis; Tyrosine | 1997 |
Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice.
Topics: Aging; Animals; Brain; Energy Intake; Free Radicals; Hydroxyl Radical; Liver; Male; Mice; Muscle Proteins; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Tyrosine | 1997 |
Catalytic mechanism and role of hydroxyl residues in the active site of theta class glutathione S-transferases. Investigation of Ser-9 and Tyr-113 in a glutathione S-transferase from the Australian sheep blowfly, Lucilia cuprina.
Topics: Animals; Binding Sites; Catalysis; Diptera; Glutathione Transferase; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Serine; Temperature; Tyrosine; Viscosity | 1997 |
Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats.
Topics: Aging; Animals; Antioxidants; Biomarkers; Copper; Female; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrogen Peroxide; Hydroxyl Radical; Nitrates; Nitrogen; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Serum Albumin, Bovine; Tyrosine | 1998 |
Information from the water stripe in TOCSY experiments on systems with exchangeable protons.
Topics: Amino Acids; Carbon; Cysteine; Electron Spin Resonance Spectroscopy; Hydrogen; Hydroxyl Radical; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Nitrogen; Peptides; Protons; Solvents; Sucrose; Threonine; Time Factors; Tyrosine; Water | 1998 |
In vitro effects of oxygen-derived free radicals on type I and type II cAMP-dependent protein kinases.
Topics: Animals; Catalysis; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Hydroxyl Radical; Phosphotransferases; Protein Binding; Rabbits; Superoxides; Tryptophan; Tyrosine | 1998 |
Hydroxyl radical generation in oxygen-treated infants.
Topics: Humans; Hydroxyl Radical; Infant, Newborn; Oxygen Inhalation Therapy; Reactive Oxygen Species; Reproducibility of Results; Respiratory Distress Syndrome, Newborn; Risk Factors; Tyrosine | 1998 |
Protein L-dopa as an index of hydroxyl radical attack on protein tyrosine.
Topics: Animals; Chromatography, High Pressure Liquid; Hydroxyl Radical; Hydroxylation; Levodopa; Rats; Tyrosine | 1998 |
Estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Chromatography, Liquid; Electrochemistry; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Models, Chemical; Oxidative Stress; Parabens; Salicylic Acid; Tyrosine | 1999 |
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.
Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine | 1999 |
Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.
Topics: Animals; Corpus Striatum; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Male; Mazindol; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Phenylalanine; Rats; Rats, Sprague-Dawley; Salicylic Acid; Serotonin; Tyrosine | 1999 |
Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine.
Topics: Animals; Hydroxyl Radical; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Physical Exertion; Proteins; Rats; Rats, Wistar; Swimming; Tyrosine | 1999 |
Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: evidence for neutrophil-mediated hydroxylation, nitration, and chlorination.
Topics: Adolescent; Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Linear Models; Male; Middle Aged; Neutrophil Activation; Neutrophils; Nitrates; Oxidants; Oxidative Stress; Proteins; Respiration, Artificial; Respiratory Distress Syndrome; Statistics, Nonparametric; Tyrosine | 1999 |
The hydroxyl radical formation system in polymorphonuclear leukocytes.
Topics: Animals; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Neutrophils; Peroxidase; Phenylalanine; Swine; Tyrosine | 1999 |
Role of the N-terminal region of ribosomal protein S7 in its interaction with 16S rRNA which binds to the concavity formed by the beta-ribbon arm and the alpha-helix.
Topics: Arginine; Circular Dichroism; Dose-Response Relationship, Drug; Geobacillus stearothermophilus; Hydroxyl Radical; Kinetics; Lysine; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Nucleic Acid Conformation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Ribosomal Proteins; RNA, Ribosomal, 16S; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1999 |
The use of phenylalanine to detect hydroxyl radical production in vivo: a cautionary note.
Topics: Animals; Cats; Chromatography, High Pressure Liquid; False Positive Reactions; Hydroxyl Radical; Phenylalanine; Tyrosine | 1999 |
Identification of the sites of hydroxyl radical reaction with peptides by hydrogen/deuterium exchange: prevalence of reactions with the side chains.
Topics: Deuterium; Dithiothreitol; DNA Footprinting; Enkephalin, Leucine-2-Alanine; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron; Leucine; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tyrosine | 2000 |
Oxidative dimerization of proteins: role of tyrosine accessibility.
Topics: Animals; Chickens; Dimerization; Female; Free Radicals; Hydroxyl Radical; In Vitro Techniques; Models, Molecular; Muramidase; Nitrogen; Oxidation-Reduction; Protein Structure, Quaternary; Proteins; Turkeys; Tyrosine | 2000 |
Involvement of peroxynitrite and hydroxyradical generated from nitric oxide in hypoxia/reoxygenation injury in rat cerebrocortical slices.
Topics: Adenosine Triphosphate; Animals; Cell-Free System; Cerebral Cortex; Cyclic AMP; Enzyme Inhibitors; Hydroxyl Radical; Hypoxia; Male; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Tyrosine | 2000 |
Role of the carbonate radical anion in tyrosine nitration and hydroxylation by peroxynitrite.
Topics: Anions; Bicarbonates; Carbon Dioxide; Carbonates; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Nitrates; Nitric Oxide; Spectrophotometry, Ultraviolet; Tyrosine | 2000 |
Towards models of vanadate-dependent haloperoxidases: the hydroxyl side chain.
Topics: Binding Sites; Cysteine; Homoserine; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Structure; Peroxidases; Protein Tyrosine Phosphatases; Serine; Threonine; Tyrosine; Vanadates | 2000 |
Amphetamine increases glutamate efflux in the rat ventral tegmental area by a mechanism involving glutamate transporters and reactive oxygen species.
Topics: Amino Acid Transport System X-AG; Amphetamine; Animals; ATP-Binding Cassette Transporters; Behavior, Animal; Calcium; Central Nervous System Stimulants; Cyclic N-Oxides; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Phenylalanine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine; Ventral Tegmental Area | 2000 |
Transformation of beta-amyloid (A beta) (1-42) tyrosine to L-dopa as the result of in vitro hydroxyl radical attack.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Hydroxylation; Inflammation; Levodopa; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Tyrosine | 2000 |
Detection of hydroxyl radicals by D-phenylalanine hydroxylation: a specific assay for hydroxyl radical generation in biological systems.
Topics: Cell Survival; Chromatography, High Pressure Liquid; Free Radicals; Humans; Hydroxyl Radical; Hydroxylation; Neutrophils; Phenylalanine; Tyrosine | 2001 |
Lead-induced hypertension. III. Increased hydroxyl radical production.
Topics: Animals; Blood Pressure; Free Radical Scavengers; Hydroxyl Radical; Hypertension; Lead; Lipid Peroxides; Male; Rats; Rats, Sprague-Dawley; Thiourea; Tyrosine | 2001 |
A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease.
Topics: Animals; Aorta; Arteriosclerosis; Diabetes Mellitus, Experimental; Glucose; Glycated Hemoglobin; Hydroxyl Radical; Lipids; Macaca fascicularis; Male; Mass Spectrometry; Oxidation-Reduction; Time Factors; Tyrosine | 2001 |
Light-dependent generation of reactive oxygen species in cell culture media.
Topics: Azides; Culture Media; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fluoresceins; Fluorescent Dyes; Folic Acid; Hydrolysis; Hydroxyl Radical; Light; Oxidation-Reduction; Oxygen; Phenolsulfonphthalein; Photochemistry; Piperazines; Pyridoxine; Reactive Oxygen Species; Rhodamines; Riboflavin; Singlet Oxygen; Spin Labels; Superoxides; Tryptophan; Tyrosine | 2001 |
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution.
Topics: Bicarbonates; Cyclic N-Oxides; Free Radicals; Hydroxyl Radical; Lipid Bilayers; Liposomes; Mass Spectrometry; Membranes, Artificial; Molsidomine; Nitrates; Nitrosation; Oxidation-Reduction; Solutions; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spin Labels; Tyrosine; Water | 2001 |
Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation.
Topics: Aged; Atrial Appendage; Atrial Fibrillation; Biomarkers; Blotting, Western; Chronic Disease; Creatine Kinase; Creatine Kinase, MB Form; DNA; Electrophoresis, Polyacrylamide Gel; Energy Metabolism; Female; Humans; Hydroxyl Radical; Isoenzymes; Male; Middle Aged; Myocardial Contraction; Myocardium; Myofibrils; Myosins; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protein Isoforms; Proteins; Tyrosine | 2001 |
-OONO: rebounding from nitric oxide.
Topics: Administration, Inhalation; Animals; Endothelium, Vascular; Epoprostenol; Hemoglobins; Humans; Hydroxyl Radical; Hypertension, Pulmonary; Nitrates; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Pneumonia; Prostaglandin H2; Prostaglandins H; Signal Transduction; Superoxides; Tyrosine | 2001 |
Hydroxyl radical formation and oxidative DNA damage induced by areca quid in vivo.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Adult; Animals; Areca; Cricetinae; Deoxyguanosine; DNA Damage; Female; Humans; Hydroxyl Radical; Male; Mastication; Mouth Mucosa; Oxidative Stress; Saliva; Tyrosine | 2002 |
Oxidative modification of proteins: oxidation of tryptophan and production of dityrosine in purified proteins using Fenton's system.
Topics: Albumins; Ethanol; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Sulfhydryl Compounds; Superoxide Dismutase; Tryptophan; Tyrosine | 2002 |
In vivo production of hydroxyl radical by Enterococcus faecalis colonizing the intestinal tract using aromatic hydroxylation.
Topics: Animals; Chromatography, High Pressure Liquid; Colon; Electron Spin Resonance Spectroscopy; Enterococcus faecalis; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Intestines; Nitrobenzenes; Nitrogen Oxides; Oxidative Stress; Phenylalanine; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2002 |
Ciclopirox prevents peroxynitrite toxicity in astrocytes by maintaining their mitochondrial function: a novel mechanism for cytoprotection by ciclopirox.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cell Cycle; Cell Death; Cells, Cultured; Ciclopirox; Flow Cytometry; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Molsidomine; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Pyridones; Rats; Rats, Sprague-Dawley; Rhodamines; Serum Albumin, Bovine; Superoxides; Tyrosine | 2002 |
Enhanced oligomerization of the alpha-synuclein mutant by the Cu,Zn-superoxide dismutase and hydrogen peroxide system.
Topics: alpha-Synuclein; Amino Acid Substitution; Anserine; Antioxidants; Antiparkinson Agents; Biopolymers; Carnosine; Chelating Agents; Codon; Copper; Edetic Acid; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Isopropyl Thiogalactoside; Lewy Bodies; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Oxidative Stress; Parkinson Disease; Phenylmethylsulfonyl Fluoride; Point Mutation; Resins, Synthetic; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Synucleins; Tyrosine | 2003 |
Evidence of an electron-transfer mechanism in the peroxynitrite-mediated oxidation of 4-alkylphenols and tyrosine.
Topics: Carbon Dioxide; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Hydroxyl Radical; Oxidation-Reduction; Peroxynitrous Acid; Phenols; Tyrosine | 2003 |
PHENOLIC HYDROXYL IONIZATION IN PEPSINOGEN.
Topics: Enzyme Precursors; Fluorescence; Hydrogen-Ion Concentration; Hydroxyl Radical; Ions; Pepsin A; Pepsinogen A; Pepsinogens; Phenols; Research; Spectrophotometry; Tyrosine; Urea | 1964 |
HPLC and LC-MS studies of hydroxylation of phenylalanine as an assay for hydroxyl radicals generated from Udenfriend's reagent.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Hydroxylation; Indicators and Reagents; Mass Spectrometry; Phenylalanine; Tyrosine | 2003 |
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
Topics: Aldehydes; Animals; Biomarkers; Body Weight; Carboxylic Acids; Cysteine; Dinitrophenols; Energy Intake; Free Radical Scavengers; Gentamicins; Hydroxyl Radical; Immunohistochemistry; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine; Urine | 2004 |
Comparison of low-flow cardiopulmonary bypass and circulatory arrest on brain oxygen and metabolism.
Topics: Animals; Animals, Newborn; Brain; Cardiopulmonary Bypass; Corpus Striatum; Dopamine; Extracellular Space; Heart Arrest, Induced; Hydroxyl Radical; Hypothermia, Induced; Microdialysis; Oxygen; Swine; Tyrosine | 2004 |
UV photolysis of 3-nitrotyrosine generates highly oxidizing species: a potential source of photooxidative stress.
Topics: Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Oxidative Stress; Photolysis; Reactive Oxygen Species; Tyrosine; Ultraviolet Rays | 2004 |
Hydroxyl radical oxidation of cytochrome c by aerobic radiolysis.
Topics: Aerobiosis; Amino Acid Sequence; Animals; Cytochromes c; Dose-Response Relationship, Radiation; Electrons; Heme; Horses; Hydroxyl Radical; Hydroxylation; Intracellular Membranes; Methionine; Mitochondria, Heart; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Protein Conformation; Pulse Radiolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tyrosine | 2004 |
Biochemical properties of new synthetic carnosine analogues containing the residue of 2,3-diaminopropionic acid: the effect of N-acetylation.
Topics: Acetylation; Antioxidants; beta-Alanine; Biochemistry; Carnosine; Dipeptidases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Free Radical Scavengers; Humans; Hydrolysis; Hydroxyl Radical; Molecular Mimicry; Peroxynitrous Acid; Structure-Activity Relationship; Tyrosine | 2005 |
Role of reactive radicals in degeneration of the auditory system of mice following cisplatin treatment.
Topics: Aldehydes; Animals; Antineoplastic Agents; Cisplatin; Cochlea; Free Radicals; Hair Cells, Auditory, Outer; Hydroxyl Radical; Immunohistochemistry; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Spiral Ganglion; Tyrosine | 2004 |
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.
Topics: Amino Acids; Animals; Antioxidants; Carbon; Cerebral Cortex; Chromatography, High Pressure Liquid; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Glucose; Guanidines; Hydroxyl Radical; Hyperglycemia; Lipid Metabolism; Lipid Peroxidation; Lipoproteins, LDL; Male; Mass Spectrometry; Oxidative Stress; Oxygen; Phenylalanine; Rats; Rats, Sprague-Dawley; Retina; Ribonuclease, Pancreatic; Temperature; Tyrosine | 2005 |
Probing the hydroxyl radical-mediated reactivity of peroxynitrite by a spin-labeling fluorophore.
Topics: Carbon Dioxide; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Fluorescent Dyes; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxyl Radical; Indicators and Reagents; Peroxynitrous Acid; Phenylalanine; Reproducibility of Results; Solvents; Spectrometry, Fluorescence; Spin Labels; Tyrosine | 2005 |
Urinary ortho-tyrosine excretion in diabetes mellitus and renal failure: evidence for hydroxyl radical production.
Topics: Aged; Cross-Sectional Studies; Diabetic Nephropathies; Female; Humans; Hydroxyl Radical; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Phenylalanine; Tyrosine | 2005 |
Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase.
Topics: Aged; Cataract; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dihydroxyphenylalanine; Eye Proteins; Humans; Hydroxyl Radical; Lens, Crystalline; Middle Aged; Phenylalanine; Solubility; Tyrosine; Water | 2005 |
Mode of action of poly(vinylpyridine-N-oxide) in preventing silicosis: effective scavenging of carbonate anion radical.
Topics: Bicarbonates; Free Radical Scavengers; Humans; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Peroxynitrous Acid; Polyvinylpyridine N-Oxide; Quartz; Reactive Oxygen Species; Silicosis; Tyrosine | 2006 |
Heme catalyzes tyrosine 385 nitration and inactivation of prostaglandin H2 synthase-1 by peroxynitrite.
Topics: Amino Acid Sequence; Animals; Apoenzymes; Binding Sites; Catalysis; Chromatography, Ion Exchange; Cyclooxygenase 1; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Heme; Hemin; Holoenzymes; Hydroxyl Radical; Male; Models, Chemical; Molecular Sequence Data; Molsidomine; Peroxynitrous Acid; Seminal Vesicles; Sheep; Tyrosine | 2006 |
Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydroxyl Radical; Hypochlorous Acid; Immunohistochemistry; Lung; Male; Masoprocol; Ozone; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Singlet Oxygen; Superoxides; Tyrosine | 2006 |
Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydroxyl Radical; Hydroxylation; Male; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Perfusion; Phenylalanine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Tyrosine | 2006 |
CXCR2 blockade reduces radical formation in hyperoxia-exposed newborn rat lung.
Topics: Animals; Animals, Newborn; Dinoprost; Hydroxyl Radical; Hyperoxia; Lung; Neutrophils; Oxygen; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Receptors, Interleukin-8B; Tyrosine | 2006 |
Structure of the Y94F mutant of Escherichia coli thymidylate synthase.
Topics: Amino Acid Substitution; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Hydroxyl Radical; Phenylalanine; Thymidylate Synthase; Tyrosine; Water | 2006 |
Hydroxylation of 3-nitrotyrosine and its derivatives by gamma irradiation.
Topics: Dose-Response Relationship, Radiation; Gamma Rays; Hydroxyl Radical; Hydroxylation; Radiation Dosage; Tyrosine | 2006 |
Radiation-induced oxidative damage to the DNA-binding domain of the lactose repressor.
Topics: Amino Acid Sequence; Bacterial Proteins; Cesium Radioisotopes; Circular Dichroism; DNA-Binding Proteins; Hydroxyl Radical; Lac Repressors; Methionine; Oxidation-Reduction; Protein Denaturation; Protein Renaturation; Protein Structure, Secondary; Repressor Proteins; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Tyrosine | 2007 |
Novel inhibitors of glycation and AGE formation.
Topics: Animals; Ascorbic Acid; Body Weight; Butyrates; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dyslipidemias; Glycation End Products, Advanced; Glycosylation; Hydroxyl Radical; Hypoglycemic Agents; Kidney; Lipid Metabolism; Lipoproteins, LDL; Male; Molecular Structure; Oxidation-Reduction; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Triglycerides; Tyrosine | 2007 |
Reaction of the carbonate radical with the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide in chemical and cellular systems: pulse radiolysis, electron paramagnetic resonance, and kinetic-competition studies.
Topics: Animals; Cell Line; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Macrophages; Mice; Pulse Radiolysis; Spin Labels; Superoxide Dismutase; Tyrosine | 2007 |
Vascular leakage induced by exposure to arsenic via increased production of NO, hydroxyl radical and peroxynitrite.
Topics: Animals; Arsenites; Blood Vessels; Capillary Permeability; Carbon; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Evans Blue; Free Radical Scavengers; Guanidines; Hydroxyl Radical; Injections, Intradermal; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Skin; Sodium Compounds; Thiourea; Tyrosine | 2008 |
Host-guest interaction of L-tyrosine with beta-cyclodextrin.
Topics: beta-Cyclodextrins; Crystallization; Hydrogen-Ion Concentration; Hydroxyl Radical; Ions; Microscopy, Electron, Scanning; Models, Chemical; Oxygen; Powders; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Tyrosine | 2008 |
Kinetic analysis of intracellular concentrations of reactive nitrogen species.
Topics: Glutathione; Hydroxyl Radical; Kinetics; Models, Biological; Nitric Oxide; Reactive Nitrogen Species; S-Nitrosoglutathione; Tyrosine | 2008 |
Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms.
Topics: Amino Acids; Crystallography, X-Ray; Cysteine; Hydrogen; Hydrogen Bonding; Hydroxyl Radical; Protein Conformation; Protein Structure, Secondary; Serine; Sulfhydryl Compounds; Threonine; Tyrosine | 2008 |
Mechanisms of peroxynitrite-mediated nitration of tyrosine.
Topics: Carbon Dioxide; Carbonates; Hydroxyl Radical; Nitrates; Nitrogen Dioxide; Peroxynitrous Acid; Tyrosine | 2009 |
Ferritin-dependent radical generation in rat liver homogenates.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Chelating Agents; Dehydroascorbic Acid; Edetic Acid; Electron Spin Resonance Spectroscopy; Ferritins; Hydroxyl Radical; Iron; Kinetics; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Protein Conformation; Rats; Rats, Wistar; Sulfhydryl Compounds; Tryptophan; Tyrosine | 2009 |
A new biomarker of protein oxidation degree and site using angiotensin as the target by MS.
Topics: Angiotensins; Biomarkers; Chromatography, High Pressure Liquid; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Phenylalanine; Proteins; Tandem Mass Spectrometry; Tyrosine | 2010 |
Endogenous 3,4-dihydroxyphenylalanine and dopaquinone modifications on protein tyrosine: links to mitochondrially derived oxidative stress via hydroxyl radical.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Benzoquinones; Brain; Cytoskeletal Proteins; Dihydroxyphenylalanine; Hydroxyl Radical; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Myocardium; Organ Specificity; Oxidative Stress; Peptides; Tyrosine | 2010 |
[The functional properties and oxidative modification of plasma and neutrophil proteins in community-acquired pneumonia].
Topics: Adolescent; Adult; Community-Acquired Infections; Female; Humans; Hydroxyl Radical; Lung; Male; Middle Aged; Neutrophils; Oxidation-Reduction; Oxidative Stress; Peroxidase; Plasma; Pneumonia; Protein Carbonylation; Tryptophan; Tyrosine; Young Adult | 2010 |
Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.
Topics: Animals; Antioxidants; Caspase 3; Cell Line; Clone Cells; Cytokines; Enzyme Inhibitors; Fluoresceins; Hydrogen Peroxide; Hydroxyl Radical; Insulin; Insulin-Secreting Cells; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Inbred Lew; Tyrosine | 2011 |
[Studies on the oxidation of tyrosine induced by hydroxyl radical with fluorescence spectroscopic method].
Topics: Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Spectrometry, Fluorescence; Tyrosine | 2011 |
Rapid generation of dityrosine cross-linked Aβ oligomers via Cu-redox cycling.
Topics: Amyloid beta-Peptides; Ascorbic Acid; Copper; Cross-Linking Reagents; Hydroxyl Radical; Immunoblotting; Kinetics; Oxidation-Reduction; Peptide Fragments; Protein Multimerization; Protein Structure, Secondary; Spectrometry, Fluorescence; Tyrosine | 2012 |
Ginsenoside Rb1 directly scavenges hydroxyl radical and hypochlorous acid.
Topics: Cell-Free System; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginsenosides; Hydroxyl Radical; Hypochlorous Acid; Mass Spectrometry; Oxidation-Reduction; Oxidative Stress; Tyrosine | 2012 |
Computational study on the attack of ·OH radicals on aromatic amino acids.
Topics: Amino Acids, Aromatic; Hydroxyl Radical; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenylalanine; Proteins; Stereoisomerism; Thermodynamics; Tryptophan; Tyrosine | 2013 |
Substrate-mediated proton relay mechanism for the religation reaction in topoisomerase II.
Topics: Arginine; Biocatalysis; DNA Topoisomerases, Type II; Hydroxyl Radical; Models, Molecular; Protons; Quantum Theory; Saccharomyces cerevisiae Proteins; Substrate Specificity; Tyrosine | 2014 |
Protein oxidation: identification and utilisation of molecular markers to differentiate singlet oxygen and hydroxyl radical-mediated oxidative pathways.
Topics: Hydroxyl Radical; Oligopeptides; Oxidation-Reduction; Reactive Oxygen Species; Singlet Oxygen; Tryptophan; Tyrosine; Ultraviolet Rays | 2013 |
Oxidative and nitrosative stress induced in myofibrillar proteins by a hydroxyl-radical-generating system: impact of nitrite and ascorbate.
Topics: Ascorbic Acid; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hydroxyl Radical; Myofibrils; Nitrites; Oxidation-Reduction; Oxidative Stress; Proteins; Schiff Bases; Tryptophan; Tyrosine | 2014 |
ONOOH does not react with H2: Potential beneficial effects of H2 as an antioxidant by selective reaction with hydroxyl radicals and peroxynitrite.
Topics: Antioxidants; Hydrogen; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Tyrosine | 2014 |
Generation Mechanism of Deferoxamine Radical by Tyrosine-Tyrosinase Reaction.
Topics: Agaricales; Deferoxamine; Electron Transport; Hydroxyl Radical; Monophenol Monooxygenase; Protons; Tyrosine | 2015 |
Insulin Therapy of Nondiabetic Septic Patients Is Predicted by para-Tyrosine/Phenylalanine Ratio and by Hydroxyl Radical-Derived Products of Phenylalanine.
Topics: Aged; Aged, 80 and over; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Female; Glucose; Humans; Hydroxyl Radical; Insulin; Isomerism; Male; Middle Aged; Phenylalanine; Shock, Septic; Tyrosine | 2015 |
Oxidation of Tyrosine-Phosphopeptides by Titanium Dioxide Photocatalysis.
Topics: Catalysis; Hydroxyl Radical; Oxidation-Reduction; Phosphopeptides; Phosphorylation; Titanium; Tyrosine; Ultraviolet Rays | 2016 |
The Role of the Glutathione System in Oxidative Modification of Proteins and Dysregulation of Apoptosis in Jurkat Tumor Cells.
Topics: Apoptosis; Buthionine Sulfoximine; Enzyme Inhibitors; Gene Expression; Glutamate-Cysteine Ligase; Glutathione; Humans; Hydroxyl Radical; Jurkat Cells; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Tryptophan; Tyrosine | 2017 |
Detection and scavenging of hydroxyl radical via D-phenylalanine hydroxylation in human fluids.
Topics: Adult; Chocolate; Diet; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Iron; Male; Middle Aged; Milk, Human; Phenylalanine; Pregnancy; Reproducibility of Results; Semen; Thiourea; Tyrosine; Young Adult | 2018 |
Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light.
Topics: Aldehydes; Animals; Hydroxyl Radical; Liver; Mice; Oxidation-Reduction; Phenols; Proteins; Proteome; Tyrosine; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification | 2018 |
M. leprae HSP18 suppresses copper (II) mediated ROS generation: Effect of redox stress on its structure and function.
Topics: Ascorbic Acid; Bacterial Proteins; Copper; Heat-Shock Proteins; Hydrogen Peroxide; Hydroxyl Radical; Macrophages; Molecular Chaperones; Mycobacterium leprae; Oxidation-Reduction; Reactive Oxygen Species; Recombinant Proteins; Tyrosine | 2020 |
NMR Observation of Intermolecular Hydrogen Bonds between Protein Tyrosine Side-Chain OH and DNA Phosphate Groups.
Topics: DNA; Hydrogen Bonding; Hydroxyl Radical; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Particle Size; Phosphates; Surface Properties; Tyrosine | 2020 |
Oxidative radicals (HO
Topics: Free Radicals; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Proteins; Tyrosine | 2021 |