tyrosine has been researched along with gw 7845 in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 21 (72.41) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gilmer, T; Risingsong, R; Sporn, MB; Suh, N; Wang, Y; Williams, CR; Willson, TM | 1 |
| Brown, KK; Glass, CK; Li, AC; Palinski, W; Silvestre, MJ; Willson, TM | 1 |
| Chatterjee, VK; Nugent, C; O'Rahilly, S; Prins, JB; Savage, D; Wentworth, JM; Whitehead, JP | 1 |
| Brosnan, CF; Dumitrescu-Ozimek, L; Feinstein, DL; Galea, E; Gavrilyuk, V; Heneka, MT; Landreth, GE; Pershadsingh, HA; Weinberg, G; Whitacre, CC | 1 |
| Jensen, BA; Mann, KK; Ryu, HY; Schlezinger, JJ; Sherr, DH | 1 |
| Chen, YE; Fu, M; Lin, Y; Mao, Z; Zhang, J; Zhu, X | 1 |
| Baker, SF; Brown, J; Davis, B; Hong, G; Khatoon, N | 1 |
| Baugh, MD; Edwards, DR; Gavrilovic, J; Hogan, A; Hughes, DA; Sampson, MJ; Worley, JR | 1 |
| Chen, YE; Fu, M; Lin, Y; McLntee, FL; Xiao, H; Zhang, J; Zhu, X | 1 |
| Bonev, AD; Eckman, DM; Gomez, MF; Heppner, TJ; Nelson, MT; Petkov, GV | 1 |
| Grommes, C; Heneka, MT; Landreth, GE; Schlegel, U | 1 |
| Bai, R; Dettin, LE; Glazer, RI; Kopelovich, L; Kopleovich, L; Kozikowski, AP; Russell, RG; Wei, ZL; Yin, Y | 1 |
| Abbot, EL; Buchan, KW; Hassall, DG; McCormack, JG; Reynet, C; Yeaman, SJ | 1 |
| Dannals, RF; Foss, CA; Henke, BR; Mathews, WB; Pomper, MG; Ravert, HT; Stoermer, D | 1 |
| Emberley, JK; Schlezinger, JJ; Sherr, DH | 1 |
| Huang, XH; Sun, K; Wang, Q | 2 |
| Chen, L; Chen, W; Diehl, AM; Stimpson, SA; Yang, L; Zhao, C | 1 |
| Bissonnette, SL; Emberley, JK; Schlezinger, JJ; Sherr, DH | 1 |
| Bouancheau, D; Denis, MG; Jarry, A; Laboisse, CL; Masson, D; Mosnier, JF; Mottier, S; Toquet, C | 1 |
| Cancedda, FD; Cancedda, R; Ulivi, V | 1 |
| Chen, XL; Cheng, T; Chu, TG; Gao, WY; Jiang, LF; Li, XY; Li, ZJ; Pan, H; Yang, JQ; Yi, CG; Yu, Q; Zhang, GY; Zheng, MH; Zhou, FY | 1 |
| Choi, SP; Park, KM; Park, KW; Tontonoz, P; Waki, H | 1 |
| Bissonnette, SL; Haas, A; Mann, KK; Schlezinger, JJ | 1 |
| Billheimer, J; Fuki, I; Macphee, C; Millar, JS; Naik, SU; Rader, DJ; Toh, SA; Walker, M | 1 |
| DuBois, RN; Guo, L; Ning, W; Wang, D; Xie, D | 1 |
| Glazer, RI; Kopelovich, L; Upadhyay, G; Yin, Y; Yuan, H | 1 |
| Alimirah, F; Hawthorne, M; Kalra, A; Kopelovich, L; Mehta, RG; Mehta, RR; Peng, X; Roy, S | 1 |
| Chang, SH; Jang, BH; Kim, S; Li, DY; Park, KM; Park, KW; Song, NJ; Tontonoz, P; Waki, H; Yun, UJ | 1 |
29 other study(ies) available for tyrosine and gw 7845
| Article | Year |
|---|---|
A new ligand for the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), GW7845, inhibits rat mammary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Drug Screening Assays, Antitumor; Female; Ligands; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Tamoxifen; Transcription Factors; Tyrosine | 1999 |
Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice.
Topics: Animals; Arteriosclerosis; Base Sequence; CD36 Antigens; DNA Primers; Female; Gene Expression; Humans; Insulin Resistance; Ligands; Male; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazoles; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, LDL; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Rosiglitazone; Scavenger Receptors, Class B; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
Topics: 3T3 Cells; Adenoviridae; Adipocytes; Animals; Benzophenones; Cell Membrane; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Green Fluorescent Proteins; Hypoglycemic Agents; Insulin; Luminescent Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Mutation; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine | 2001 |
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis.
Topics: Animals; Cerebellum; Cerebral Cortex; DNA-Binding Proteins; Encephalomyelitis, Autoimmune, Experimental; Female; Glycoproteins; Humans; Hypoglycemic Agents; I-kappa B Proteins; Ligands; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxazoles; Peptide Fragments; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Remission Induction; Spinal Cord; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2002 |
Peroxisome proliferator-activated receptor gamma-mediated NF-kappa B activation and apoptosis in pre-B cells.
Topics: Animals; Apoptosis; B-Lymphocytes; Bone Marrow Cells; Cell Line; Cell Line, Transformed; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxazoles; Peroxisome Proliferators; Peroxisomes; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2002 |
Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells.
Topics: Anilides; Aorta; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Humans; Hypoglycemic Agents; Inhibitor of Differentiation Protein 2; Muscle, Smooth, Vascular; Oxazoles; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; RNA, Messenger; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tyrosine | 2003 |
PPAR gamma-dependent anti-inflammatory action of rosiglitazone in human monocytes: suppression of TNF alpha secretion is not mediated by PTEN regulation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Monocytes; Morpholines; Oxazoles; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins; Tyrosine | 2003 |
Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid.
Topics: ADAM Proteins; ADAMTS4 Protein; Alitretinoin; Cell Line; Humans; Macrophages; Matrix Metalloproteinase 9; Metalloendopeptidases; Metalloproteases; Oxazoles; Procollagen N-Endopeptidase; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tretinoin; Tyrosine | 2003 |
Interferon regulatory factor-1 mediates PPARgamma-induced apoptosis in vascular smooth muscle cells.
Topics: Adenoviridae; Animals; Aorta; Apoptosis; Cells, Cultured; Chlorocebus aethiops; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Interferon Regulatory Factor-1; Ligands; Muscle, Smooth, Vascular; Oxazoles; Phosphoproteins; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA Stability; RNA, Messenger; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tyrosine; Up-Regulation | 2004 |
Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries.
Topics: Algorithms; Animals; Barium; Benzophenones; Blood Pressure; Calcium Channels; Electrophysiology; Female; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Cells; Muscle Tonus; Muscle, Smooth, Vascular; Oxazoles; Patch-Clamp Techniques; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Tyrosine; Vasodilation | 2005 |
The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Migration Inhibition; Cell Movement; Cell Survival; Glioma; Humans; Ligands; Oxazoles; PPAR gamma; Rats; Thiazolidinediones; Tyrosine | 2005 |
Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Adenosquamous; Carcinoma, Ductal; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; Female; Gene Expression Profiling; Mammary Neoplasms, Experimental; Mice; Oxazoles; PPAR delta; PPAR gamma; Thiazoles; Tyrosine | 2005 |
Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells.
Topics: Butyrates; Cells, Cultured; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucose; Humans; Insulin; Isoenzymes; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts, Skeletal; Oxazoles; Phenylurea Compounds; PPAR alpha; PPAR delta; PPAR gamma; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Messenger; Thiazoles; Tyrosine | 2005 |
Synthesis and biodistribution of (11)C-GW7845, a positron-emitting agonist for peroxisome proliferator-activated receptor-{gamma}.
Topics: Animals; Breast Neoplasms; Carbon Radioisotopes; Female; Isotope Labeling; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Oxazoles; Positron-Emission Tomography; PPAR gamma; Radiopharmaceuticals; Tissue Distribution; Tyrosine | 2005 |
Activation of multiple mitogen-activated protein kinases in pro/pre-B cells by GW7845, a peroxisome proliferator-activated receptor gamma agonist, and their contribution to GW7845-induced apoptosis.
Topics: Animals; Apoptosis; B-Lymphocytes; Caspases; Cell Line; Cytochromes c; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Oxazoles; Phosphorylation; PPAR gamma; Protein Kinase Inhibitors; Tyrosine | 2006 |
PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression.
Topics: Anilides; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Connective Tissue Growth Factor; Dose-Response Relationship, Drug; Gene Expression; Hepatocytes; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Ligands; Oxazoles; PPAR gamma; Prostaglandin D2; Rats; RNA, Messenger; Transforming Growth Factor beta1; Tyrosine | 2006 |
PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells.
Topics: Activin Receptors, Type I; Adipocytes; Benzamides; Cell Line; Culture Media; Dioxoles; Extracellular Matrix Proteins; Gene Expression; Humans; Liver; Oxazoles; Phosphorylation; PPAR gamma; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Tyrosine | 2006 |
An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.
Topics: Animals; Apoptosis; Bone Marrow Cells; Caspase Inhibitors; Caspases; Cytochromes c; Immunoblotting; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondrial Membranes; Oxazoles; PPAR gamma; Signal Transduction; Tyrosine | 2007 |
Low expression of ORF4, a dominant negative variant of peroxisome proliferator-activated receptor gamma, in colorectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Alternative Splicing; Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Male; Middle Aged; Oxazoles; PPAR gamma; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2007 |
15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation.
Topics: Acute-Phase Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Cartilage; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Diclofenac; Dinoprostone; Down-Regulation; Enzyme Induction; Enzyme Repression; Imidazoles; Inflammation; Intramolecular Oxidoreductases; Lipocalin-2; Lipocalins; Lipopolysaccharides; Mice; NF-kappa B; Oncogene Proteins; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; PPAR alpha; PPAR gamma; Prostaglandin D2; Prostaglandin-E Synthases; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Time Factors; Tyrosine | 2008 |
Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro.
Topics: Cell Growth Processes; Cells, Cultured; Cicatrix, Hypertrophic; Connective Tissue; Connective Tissue Growth Factor; Dose-Response Relationship, Immunologic; Extracellular Matrix; Fibroblasts; Humans; Oxazoles; PPAR gamma; Prostaglandin D2; Transcriptional Activation; Transforming Growth Factor beta; Tyrosine | 2009 |
[Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta1-induced connective tissue growth factor expression in rat hepatic stellate cells].
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Hepatic Stellate Cells; Oxazoles; PPAR gamma; Rats; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1; Tyrosine | 2009 |
The small molecule phenamil is a modulator of adipocyte differentiation and PPARgamma expression.
Topics: 3T3 Cells; Adipocytes; Amiloride; Animals; CCAAT-Enhancer-Binding Protein-delta; Cell Differentiation; DNA-Binding Proteins; Gene Expression Regulation; Harmine; Mice; Molecular Structure; Monoamine Oxidase Inhibitors; Oxazoles; PPAR gamma; Proto-Oncogene Proteins c-ets; Signal Transduction; Sodium Channel Blockers; Transcription Factors; Tyrosine | 2010 |
The role of CaMKII in calcium-activated death pathways in bone marrow B cells.
Topics: Animals; Apoptosis; B-Lymphocytes; Bone Marrow Cells; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Ligands; MAP Kinase Kinase 4; Membrane Potential, Mitochondrial; Mice; Oxazoles; Trialkyltin Compounds; Tyrosine | 2010 |
PPARγ activation redirects macrophage cholesterol from fecal excretion to adipose tissue uptake in mice via SR-BI.
Topics: Adipose Tissue; Animals; Cell Line; Cholesterol; Feces; Female; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazoles; PPAR gamma; Scavenger Receptors, Class B; Tyrosine | 2011 |
Peroxisome proliferator-activated receptor δ confers resistance to peroxisome proliferator-activated receptor γ-induced apoptosis in colorectal cancer cells.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Inhibitor of Apoptosis Proteins; Oxazoles; PPAR delta; PPAR gamma; Survivin; Thiazoles; Tyrosine | 2012 |
Stem cell antigen-1 deficiency enhances the chemopreventive effect of peroxisome proliferator-activated receptorγ activation.
Topics: Animals; Anticarcinogenic Agents; Antigens, Ly; Antineoplastic Agents; Cell Line, Tumor; Genetic Predisposition to Disease; Heterozygote; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oxazoles; Phenotype; PPAR gamma; RNA Interference; Signal Transduction; Thiazoles; Tyrosine | 2012 |
PPARγ antagonist GW9662 induces functional estrogen receptor in mouse mammary organ culture: potential translational significance.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anilides; Animals; Anticarcinogenic Agents; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Oxazoles; PPAR gamma; Precancerous Conditions; Receptors, Progesterone; Tamoxifen; Tissue Culture Techniques; Transcriptional Activation; Tyrosine | 2013 |
Small Molecule-Induced Complement Factor D (Adipsin) Promotes Lipid Accumulation and Adipocyte Differentiation.
Topics: Adipocytes; Adipogenesis; Animals; Cell Line; Complement C3a; Complement Factor D; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Oxazoles; Peroxisome Proliferator-Activated Receptors; Receptors, Complement; Signal Transduction; Small Molecule Libraries; Transcriptome; Tyrosine | 2016 |