tyrosine has been researched along with gw 1929 in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.17) | 18.2507 |
| 2000's | 17 (36.96) | 29.6817 |
| 2010's | 25 (54.35) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Adkison, K; Binz, JG; Blanchard, SG; Brown, HR; Brown, KK; Cobb, JE; Faison, W; Harrington, WW; Hashim, MA; Henke, BR; Kaldor, I; Kliewer, SA; Lehmann, JM; Lenhard, JM; Menius, JA; Mook, R; Noble, SA; Novak, PJ; Oliver, WO; Parks, DJ; Plunket, KD; Tong, WQ; Willson, TM | 1 |
| Brown, KK; Gottschalk, WK; Harrington, WW; Kliewer, SA; Mansfield, TA; Ramachandran, RK; Sundseth, SS; Way, JM; Willson, TM | 1 |
| Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM | 1 |
| Consler, TG; Gray, JG; Iannone, MA; Parks, DJ; Pearce, KH; Stimmel, JB | 1 |
| Chatterjee, VK; Nugent, C; O'Rahilly, S; Prins, JB; Savage, D; Wentworth, JM; Whitehead, JP | 1 |
| Chi, KH; Chio, CC; Huang, WC; Lin, WW; Wu, HM | 1 |
| Han, S; Huang, RP; Sidell, N; Wanichkul, T | 1 |
| She, H; Sung, CK; Tsukamoto, H; Xiong, S | 1 |
| Bonev, AD; Eckman, DM; Gomez, MF; Heppner, TJ; Nelson, MT; Petkov, GV | 1 |
| Han, S; Rivera, HN; Roman, J | 1 |
| Coales, SJ; Griffin, PR; Hamuro, Y; Molnar, KS; Morrow, JA; Southern, MR; Tuske, SJ | 1 |
| Bouhlel, MA; Brozek, J; Chinetti-Gbaguidi, G; Derudas, B; Dièvart, R; Haulon, S; Jude, B; Marx, N; Rigamonti, E; Staels, B; Torpier, G; Zawadzki, C | 1 |
| Adams, SH; Baumann, TK; Knotts, TA; Oort, PJ; Warden, CH | 1 |
| Ametller, E; Argilés, JM; Busquets, S; Figueras, M; López-Soriano, FJ; Moore-Carrasco, R | 1 |
| Adams, SH; Bastard, JP; Buchman, VL; Clément, K; Dunn, TN; Grino, M; Knotts, TA; Luo, X; Naour, N; Ninkina, N; Oort, PJ; Pan, G; Permana, PA | 1 |
| Chang, KC; Kim, HJ; Kim, YM; Lee, JH; Nizamutdinova, IT; Seo, HG | 1 |
| Arena, V; Biscetti, F; De Angelis, G; Flex, A; Ghirlanda, G; Iuliano, L; Pecorini, G; Rizzo, P; Stigliano, E; Straface, G | 1 |
| Izawa, Y; Suzuki, N; Takahashi, S | 1 |
| Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Storelli, C | 1 |
| Bachoo, R; Dill, J; Li, S; Patel, AR; Powell, CM; Yang, XL | 1 |
| Kaundal, RK; Sharma, SS | 2 |
| Dizhe, EB; Mogilenko, DA; Orlov, SV; Perevozchikov, AP; Shavva, VS | 1 |
| Akahira, J; Hui, XG; Ito, S; Kudo, M; Matsuda, K; Nakamura, Y; Noguchi, N; Okamoto, H; Rainey, WE; Sasano, H; Satoh, F; Sugawara, A; Uruno, A; Yoshikawa, T | 1 |
| Auinger, A; Hyder, A; Kraus-Stojanowic, I; Roeder, T; Schrezenmeir, J; Zenhom, M | 1 |
| Du, J; Fan, LM; Li, JM; Meijles, D; Tickner, J | 1 |
| Amita, M; Hara, S; Igarashi, H; Kurachi, H; Takahashi, T; Tsutsumi, S | 1 |
| Devi, MS; Sudhakaran, PR | 1 |
| Angulo, J; El Assar, M; García-Septiem, J; Rodríguez-Mañas, L; Sánchez-Ferrer, CF; Vallejo, S | 1 |
| Amodeo, V; Bazan, V; Caruso, S; Cicero, G; Contaldo, C; Corsini, LR; Fanale, D; Fiorio, E; Insalaco, L; Lo Re, G; Mercanti, A; Russo, A; Surmacz, E; Terrasi, M | 1 |
| Jiang, H; Lai, N; Lu, W; Ran, P; Wang, J; Xu, L; Yang, K; Zhang, Y; Zhong, N | 1 |
| Brownell, LA; Corneliusen, B; Jia, Q; Pantier, M; Yimam, M; Zhao, J | 1 |
| Chai, JT; Choudhury, RP; Digby, JE; Handa, A; Jefferson, A; Ruparelia, N | 1 |
| Kajta, M; Szychowski, KA; Wojtowicz, AK | 1 |
| Hahn, SS; Tang, Q; Wu, J; Zhao, S; Zheng, F | 1 |
| Aguila, MB; Barbosa-da-Silva, S; Magliano, DC; Mandarim-de-Lacerda, CA; Marinho, Tde S; Souza-Mello, V | 1 |
| Jiang, H; Jiang, Q; Lu, W; Wang, J; Yang, K; Yun, X; Zhao, M | 1 |
| Honkisz, E; Wójtowicz, AK | 1 |
| Nakanishi, A; Tsukamoto, I | 1 |
| Eriksson, O; Korhonen, LT; Kukkonen, JP; Lindholm, D; Mäkelä, J; Tselykh, TV | 1 |
| Bogomolova, AM; Dizhe, EB; Efremov, AM; Mogilenko, DA; Nikitin, AA; Oleinikova, GN; Orlov, SV; Perevozchikov, AP; Shavva, VS | 1 |
| Chen, Y; Huang, J; Jiang, H; Lu, W; Wang, J; Yang, K; Zhang, C; Zhao, M; Zheng, Q | 1 |
| Li, H; Tian, MM; Wang, YY; Yan, XL; Yu, ZF | 1 |
| Gao, B; Jia, H; Li, Z; Qin, Y; Wang, H; Zhao, G | 1 |
| Fan, H; Huang, J; Liu, CZ; Tu, JF; Wang, L; Yang, JW; Yang, NN | 1 |
| Ding, W; Duan, Y; Feng, J; Li, X; Lu, Y; Qu, Z; Sun, D; Zhang, R; Zhang, X | 1 |
46 other study(ies) available for tyrosine and gw 1929
| Article | Year |
|---|---|
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
Topics: Animals; Benzophenones; Chromans; Clone Cells; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Immunohistochemistry; Logistic Models; Obesity; Phenotype; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tyrosine | 1999 |
Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Benzophenones; Diabetes Mellitus; Fatty Acids; Gene Expression; Gene Expression Profiling; Glucose; Homeostasis; Insulin; Liver; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tyrosine | 2001 |
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2001 |
Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres.
Topics: Amino Acid Motifs; Benzophenones; Cyclic AMP Response Element-Binding Protein; Estradiol; Estrogen Receptor beta; Histone Acetyltransferases; Humans; Ligands; Microspheres; Molecular Sequence Data; Nuclear Receptor Coactivator 1; Peptides; Protein Binding; Raloxifene Hydrochloride; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Tamoxifen; Transcription Factors; Tyrosine | 2001 |
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
Topics: 3T3 Cells; Adenoviridae; Adipocytes; Animals; Benzophenones; Cell Membrane; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Green Fluorescent Proteins; Hypoglycemic Agents; Insulin; Luminescent Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Mutation; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine | 2001 |
Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929.
Topics: Animals; Benzophenones; Cell Line; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Peroxisomes; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostaglandin D2; Protein Kinase C; Proto-Oncogene Proteins c-raf; ras Proteins; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Superoxides; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2002 |
Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells.
Topics: Benzophenones; Colony-Stimulating Factors; Cytokines; Endometrium; Epithelial Cells; Female; Humans; Interleukin-6; Ligands; Phenylacetates; Prostaglandin D2; Protein Array Analysis; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2003 |
Tumor necrosis factor-alpha inhibits peroxisome proliferator-activated receptor gamma activity at a posttranslational level in hepatic stellate cells.
Topics: Animals; Benzophenones; Cell Line; DNA; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Liver; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA, Messenger; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Novel PPARgamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries.
Topics: Algorithms; Animals; Barium; Benzophenones; Blood Pressure; Calcium Channels; Electrophysiology; Female; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Cells; Muscle Tonus; Muscle, Smooth, Vascular; Oxazoles; Patch-Clamp Techniques; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Tyrosine; Vasodilation | 2005 |
Peroxisome proliferator-activated receptor-gamma ligands inhibit alpha5 integrin gene transcription in non-small cell lung carcinoma cells.
Topics: Base Sequence; Benzophenones; Binding Sites; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Integrin alpha5; Ligands; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Rosiglitazone; Signal Transduction; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Tyrosine | 2005 |
Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators.
Topics: Amides; Amino Acid Sequence; Anilides; Benzophenones; Binding Sites; Deuterium Exchange Measurement; Indoles; Ligands; Mass Spectrometry; Models, Molecular; Pepsin A; Peptide Fragments; PPAR gamma; Protein Conformation; Protein Structure, Tertiary; Rosiglitazone; Sulfides; Thiazolidinediones; Tyrosine | 2006 |
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties.
Topics: Benzophenones; Biomarkers; Blood Cells; Carotid Artery Diseases; Cell Differentiation; Cells, Cultured; Foam Cells; Humans; Inflammation; Macrophages; Monocytes; Paracrine Communication; Phenotype; PPAR gamma; Stem Cells; Tyrosine | 2007 |
Characterization of Tusc5, an adipocyte gene co-expressed in peripheral neurons.
Topics: 3T3-L1 Cells; Adipocytes; Amino Acid Sequence; Animals; Benzophenones; Cell Differentiation; Ganglia, Spinal; Gene Expression Profiling; Gene Expression Regulation; Glucose; Humans; Lactic Acid; Membrane Proteins; Mice; Molecular Sequence Data; Neurons; Oligonucleotide Array Sequence Analysis; PPAR gamma; Protein Structure, Tertiary; RNA, Messenger; Sequence Homology, Amino Acid; Trigeminal Ganglion; Tumor Suppressor Proteins; Tyrosine | 2007 |
Effects of the PPARgamma agonist GW1929 on muscle wasting in tumour-bearing mice.
Topics: Animals; Benzophenones; Blotting, Western; Cachexia; Carcinoma, Lewis Lung; Glucose Transporter Type 4; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; PPAR gamma; Tyrosine | 2008 |
Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Benzophenones; Blotting, Western; Cell Differentiation; Female; gamma-Synuclein; Gene Expression; Humans; Immunohistochemistry; Indians, North American; Leptin; Mice; Obesity; Peripheral Nervous System; Polymerase Chain Reaction; PPAR gamma; Rats; RNA, Messenger; Tyrosine | 2008 |
Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anilides; Anti-Inflammatory Agents; Benzophenones; Carbon Monoxide; Cell Adhesion; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Activators; Glucose; Humans; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Organometallic Compounds; PPAR gamma; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Ribonucleotides; Signal Transduction; Thiazolidinediones; Time Factors; Transfection; Troglitazone; Tyrosine | 2009 |
Pioglitazone enhances collateral blood flow in ischemic hindlimb of diabetic mice through an Akt-dependent VEGF-mediated mechanism, regardless of PPARgamma stimulation.
Topics: Anilides; Animals; Benzophenones; Blood Flow Velocity; Blood Glucose; Collateral Circulation; Diabetes Mellitus, Experimental; Hindlimb; Hypoglycemic Agents; Ischemia; Male; Mice; Mice, Inbred C57BL; Oncogene Protein v-akt; Pioglitazone; PPAR gamma; Signal Transduction; Thiazolidinediones; Tyrosine; Up-Regulation; Vascular Endothelial Growth Factor A | 2009 |
Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia.
Topics: Analysis of Variance; Anilides; Animals; Astrocytes; Benzophenones; Cell Shape; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Hypoglycemic Agents; Lactic Acid; Neurons; Pioglitazone; PPAR gamma; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiazolidinediones; Tyrosine | 2009 |
PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.
Topics: Angiogenesis Inhibitors; Anilides; Benzhydryl Compounds; Benzophenones; Binding Sites; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Down-Regulation; Endothelial Cells; Epoxy Compounds; Gene Expression Regulation, Enzymologic; Humans; Neovascularization, Physiologic; Nitrobenzenes; PPAR gamma; Promoter Regions, Genetic; Protein Kinase C-alpha; Protein Transport; RNA Interference; RNA, Messenger; Rosiglitazone; Sulfonamides; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transfection; Tyrosine; Vascular Endothelial Growth Factor A | 2010 |
A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons.
Topics: Anilides; Animals; Animals, Newborn; Benzophenones; Cells, Cultured; Cerebellum; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Hypoglycemic Agents; Ibuprofen; Mice; Mice, Inbred C57BL; Naproxen; Neurites; Neurons; PC12 Cells; PPAR gamma; Rats; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Transfection; Tubulin; Tyrosine | 2010 |
GW1929: a nonthiazolidinedione PPARγ agonist, ameliorates neurological damage in global cerebral ischemic-reperfusion injury through reduction in inflammation and DNA fragmentation.
Topics: Analysis of Variance; Animals; Benzophenones; Brain Damage, Chronic; Brain Ischemia; Cognition Disorders; DNA Fragmentation; Gerbillinae; Hippocampus; Male; Motor Activity; Neuroprotective Agents; PPAR gamma; Reperfusion Injury; Tyrosine | 2011 |
PPARγ activates ABCA1 gene transcription but reduces the level of ABCA1 protein in HepG2 cells.
Topics: ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Benzophenones; Cell Nucleus; Down-Regulation; Hep G2 Cells; Humans; Liver; Liver X Receptors; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Orphan Nuclear Receptors; PPAR gamma; Promoter Regions, Genetic; Protein Biosynthesis; Transcription, Genetic; Transcriptional Activation; Tyrosine | 2010 |
Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production.
Topics: Adrenal Cortex; Aldosterone; Benzophenones; Benzylamines; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line; Cytochrome P-450 CYP11B2; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Ionomycin; Mutation; Pioglitazone; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Sulfonamides; Thiazolidinediones; Transcription, Genetic; Tyrosine; Zona Glomerulosa | 2011 |
PPARγ-dependent peptidoglycan recognition protein 3 (PGlyRP3) expression regulates proinflammatory cytokines by microbial and dietary fatty acids.
Topics: Benzophenones; Caco-2 Cells; Carrier Proteins; Cytokines; Fatty Acids; Gene Expression Regulation; Humans; Inflammation; NF-kappa B; PPAR gamma; Promoter Regions, Genetic; Retinoid X Receptor alpha; Signal Transduction; Tyrosine | 2011 |
Nox2-derived ROS in PPARγ signaling and cell-cycle progression of lung alveolar epithelial cells.
Topics: Animals; Benzophenones; Cell Cycle; Cell Line; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; PPAR gamma; Pulmonary Alveoli; Reactive Oxygen Species; Respiratory Mucosa; RNA, Small Interfering; Signal Transduction; Tyrosine | 2011 |
Ameliorative effects of GW1929, a nonthiazolidinedione PPARγ agonist, on inflammation and apoptosis in focal cerebral ischemic-reperfusion injury.
Topics: Animals; Apoptosis; Benzophenones; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Male; Neuroprotective Agents; PPAR gamma; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tyrosine | 2011 |
Bezafibrate restores the inhibition of FSH-induced follicular development and steroidogenesis by tumor necrosis factor-alpha through peroxisome proliferator-activated receptor-gamma pathway in an in vitro mouse preantral follicle culture.
Topics: Anilides; Animals; Benzophenones; Bezafibrate; Cells, Cultured; Female; Follicle Stimulating Hormone; Hypolipidemic Agents; In Vitro Techniques; Mice; Mice, Inbred ICR; Models, Animal; Ovarian Follicle; PPAR gamma; Signal Transduction; Steroids; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Angiogenic response of advanced glycation end products (AGEs) involves PPARgamma.
Topics: Angiogenesis Inducing Agents; Anilides; Animals; Benzophenones; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Diabetes Mellitus; E-Selectin; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Platelet Endothelial Cell Adhesion Molecule-1; PPAR gamma; RNA; Tyrosine; Vascular Endothelial Growth Factor A | 2012 |
Age-related differences in the effects of α and γ peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Benzophenones; Butyrates; Cardiovascular Diseases; Case-Control Studies; Endothelium, Vascular; Female; Free Radical Scavengers; Humans; Male; Mesenteric Arteries; Microvessels; Middle Aged; Oxidative Stress; Phenylurea Compounds; PPAR alpha; PPAR gamma; Risk Factors; Superoxide Dismutase; Superoxides; Tyrosine; Vasodilation | 2012 |
Effects of PPARγ agonists on the expression of leptin and vascular endothelial growth factor in breast cancer cells.
Topics: Benzophenones; Binding Sites; Breast Neoplasms; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Leptin; Ligands; MCF-7 Cells; PPAR gamma; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Thiazolidinediones; Tyrosine; Vascular Endothelial Growth Factor A | 2013 |
Sildenafil inhibits hypoxia-induced transient receptor potential canonical protein expression in pulmonary arterial smooth muscle via cGMP-PKG-PPARγ axis.
Topics: Animals; Benzamides; Benzophenones; Carbazoles; Cell Movement; Cell Proliferation; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Hypoxia; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphodiesterase 5 Inhibitors; Piperazines; PPAR gamma; Protein Kinase Inhibitors; Pulmonary Artery; Purines; Pyridines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Sulfones; TRPC Cation Channels; Tyrosine | 2013 |
UP780, a chromone-enriched aloe composition improves insulin sensitivity.
Topics: 3T3-L1 Cells; Adiponectin; Aloe; Animals; Benzophenones; Blood Glucose; Chemistry, Pharmaceutical; Chromones; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucosides; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Preparations; Polysaccharides; Tyrosine | 2013 |
Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells.
Topics: ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Benzophenones; Biological Transport; Cell Line; Cholesterol; Cyclic AMP; Down-Regulation; Foam Cells; Humans; Inflammation Mediators; Lipopolysaccharides; Niacin; Orphan Nuclear Receptors; Plaque, Atherosclerotic; PPAR gamma; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Transcription, Genetic; Tyrosine | 2013 |
PPAR-γ agonist GW1929 but not antagonist GW9662 reduces TBBPA-induced neurotoxicity in primary neocortical cells.
Topics: Anilides; Animals; Apoptosis; Benzophenones; Caspase 3; Cells, Cultured; Central Nervous System Agents; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Mice; Neocortex; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Polybrominated Biphenyls; PPAR gamma; Time Factors; Tyrosine | 2014 |
GW1929 inhibits α7 nAChR expression through PPARγ-independent activation of p38 MAPK and inactivation of PI3-K/mTOR: The role of Egr-1.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anilides; Benzophenones; Cell Line, Tumor; Cell Proliferation; Cell Survival; Early Growth Response Protein 1; Enzyme Activation; Humans; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; PPAR gamma; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Tyrosine | 2014 |
Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice.
Topics: Adipokines; Animals; Benzophenones; Blood Glucose; Body Weight; Diet, High-Fat; Energy Intake; Glucose Intolerance; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; PPAR alpha; Tyrosine | 2015 |
Peroxisome Proliferator-Activated Receptor γ-Mediated Inhibition on Hypoxia-Triggered Store-Operated Calcium Entry. A Caveolin-1-Dependent Mechanism.
Topics: Animals; Benzophenones; Calcium Signaling; Caveolin 1; Cell Hypoxia; Cells, Cultured; Gene Expression; Lysosomes; Male; Myocytes, Smooth Muscle; PPAR gamma; Protein Binding; Proteolysis; Pulmonary Artery; Rats, Wistar; Tyrosine; Up-Regulation | 2015 |
The role of PPARγ in TBBPA-mediated endocrine disrupting effects in human choriocarcinoma JEG-3 cells.
Topics: Anilides; Apoptosis; Benzophenones; Caspase 3; Cell Line; Cell Survival; Choriocarcinoma; Chorionic Gonadotropin, beta Subunit, Human; Endocrine Disruptors; Female; Humans; Placenta; Polybrominated Biphenyls; PPAR gamma; Pregnancy; Progesterone; Tyrosine; Uterine Neoplasms | 2015 |
n-3 polyunsaturated fatty acids stimulate osteoclastogenesis through PPARγ-mediated enhancement of c-Fos expression, and suppress osteoclastogenesis through PPARγ-dependent inhibition of NFkB activation.
Topics: Animals; Benzophenones; Bone Marrow Cells; Cells, Cultured; Cyclooxygenase 2; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Gene Expression Regulation; Male; Mesenchymal Stem Cells; NF-kappa B; Osteogenesis; PPAR gamma; Proto-Oncogene Proteins c-fos; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Transcription Factors; Tyrosine | 2015 |
Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons.
Topics: Benzophenones; Cell Line; Cyclic AMP Response Element-Binding Protein; Dopaminergic Neurons; Humans; Mitochondria; Neuroprotective Agents; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; Sirtuin 1; Transcription Factors; Tyrosine | 2016 |
PPARγ Represses Apolipoprotein A-I Gene but Impedes TNFα-Mediated ApoA-I Downregulation in HepG2 Cells.
Topics: Apolipoprotein A-I; Benzophenones; Caco-2 Cells; Down-Regulation; Enhancer Elements, Genetic; Enterocytes; Hep G2 Cells; Hepatocytes; Humans; Liver X Receptors; PPAR alpha; PPAR gamma; Tumor Necrosis Factor-alpha; Tyrosine | 2016 |
Pharmacological activation of PPARγ inhibits hypoxia-induced proliferation through a caveolin-1-targeted and -dependent mechanism in PASMCs.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Benzophenones; Caveolin 1; Cell Cycle Proteins; Cell Hypoxia; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Humans; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Pulmonary Artery; Rats, Wistar; Signal Transduction; Tyrosine; Vascular Remodeling | 2018 |
Peroxisome proliferator-activated receptor-gamma activation attenuates diabetic cardiomyopathy via regulation of the TGF-β/ERK pathway and epithelial-to-mesenchymal transition.
Topics: Animals; Benzophenones; Diabetic Cardiomyopathies; Epithelial-Mesenchymal Transition; Fibrosis; Inflammation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocardium; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Signal Transduction; Transforming Growth Factor beta; Tyrosine | 2018 |
Characterization of the metabolites of GW1929 in rat by liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Topics: Animals; Benzophenones; Chromatography, High Pressure Liquid; Female; Hepatocytes; Hydroxylation; Male; Molecular Structure; Rats; Tandem Mass Spectrometry; Tyrosine | 2020 |
Peroxisome proliferator-activated receptor-γ mediates the antihypertensive effects of acupuncture in spontaneously hypertensive rats.
Topics: Acupuncture Therapy; Anilides; Animals; Benzophenones; Blood Pressure; Brain; Heart Rate; Medulla Oblongata; Microinjections; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tyrosine; Vasomotor System | 2020 |
Acidic Microenvironment Aggravates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating M1-Polarization Through Regulating PPAR-γ Signal.
Topics: Animals; Benzophenones; Cells, Cultured; Cellular Microenvironment; Disease Models, Animal; Hydrogen-Ion Concentration; Immunity, Innate; Kupffer Cells; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Reperfusion Injury; Severity of Illness Index; Signal Transduction; Sodium Bicarbonate; Tyrosine | 2021 |