tyrosine has been researched along with glutamic acid in 379 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (9.76) | 18.7374 |
| 1990's | 81 (21.37) | 18.2507 |
| 2000's | 183 (48.28) | 29.6817 |
| 2010's | 65 (17.15) | 24.3611 |
| 2020's | 13 (3.43) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| Burke, GT; Chu, YC; Katsoyannis, PG; Zong, L | 1 |
| Muszkat, KA; Schechter, B; Sela, M | 1 |
| Alfa, CE; Hyams, JS | 1 |
| Kirsch, JF; Toney, MD | 1 |
| Baig, S; Halawa, I; Qureshi, GA | 1 |
| Bading, H; Greenberg, ME | 1 |
| Dodd, PR; Johnston, GA; Leong, DK; Maddison, JE | 1 |
| Buikhuisen, WA; Thompson, JF | 1 |
| Hamano, S; Morita, K; Oka, M; Teraoka, K | 1 |
| Palm, D; Schinzel, R | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Gobert, A; Guibert, B; Leviel, V | 1 |
| Meggio, F; Pinna, LA | 1 |
| Bell, JM; Keith, MO | 1 |
| Henriksen, EJ; Jaspers, SR; Satarug, S; Tischler, ME | 1 |
| Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE | 1 |
| Beale, D; Coadwell, J | 1 |
| Felipo, V; Grisolía, S; Miñana, MD | 1 |
| Christianson, DW; Lipscomb, WN; Mangani, S; Shoham, G | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Ellis, JS; Maurer, PH; Zeiger, AR | 1 |
| Holm, E; Leweling, H; Ritz, R; Saeger, HD; Striebel, JP | 1 |
| Fernstrom, JD; Fernstrom, MH; Volk, EA | 1 |
| Jigami, Y; Morikawa, M; Muraki, M; Tanaka, H | 1 |
| Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Wolf-Novak, LC; Ziegler, EE | 1 |
| Fujita-Yamaguchi, Y; Ramachandran, J; Sahal, D | 1 |
| Cupples, CG; Miller, JH | 1 |
| Adam, M; Deyl, Z; Horáková, M; Macek, K | 1 |
| Bridges, CD; Chytil, F; Olson, JA; Packer, L; Wolf, G | 1 |
| Baker, GL; Filer, LJ; Stegink, LD | 1 |
| Engerman, RL; Kern, TS | 1 |
| Corbet, S; Fougereau, M; Milili, M; Schiff, C | 1 |
| Gorden, P; Grunberger, G; Zick, Y | 1 |
| Lähdesmäki, P; Turpeenoja, L | 1 |
| Fujiwara, M; Higashi, T; Nagashima, H; Nakatsukasa, H; Sakata, T; Shiota, T; Takei, N; Watanabe, A | 1 |
| Gelman, M; Girault, JA; Siciliano, JC | 1 |
| Hu, BR; Kurihara, J; Wieloch, T | 1 |
| Desiderio, S; Malek, SN | 1 |
| Frankfurter, A; Kimble, M; Kuriyama, R; Levin, A; Madl, J; Nelson, D | 1 |
| Cobb, MH; Ebert, D; Goldsmith, EJ; Zhang, F; Zhang, J | 1 |
| Cai, Y; Ewan, RC; Zimmerman, DR | 1 |
| Cowburn, D; Kuriyan, J; Pant, N; Shoelson, SE; Waksman, G | 1 |
| Palacín, M; Testar, X; Viñals, F; Zorzano, A | 1 |
| Chu, HA; Debus, RJ; Nguyen, AP | 1 |
| Bedouelle, H; Nageotte, R | 1 |
| Abdul Jabbar, M; Kasturi, S; Sen, GC; Sen, I | 1 |
| Becker, S; Palm, D; Schinzel, R | 1 |
| Joshi, AA; McDonald, MJ | 1 |
| Catherwood, BD; Marzilli, LG; Nanes, MS; Rubin, J; Titus, L | 1 |
| Bulinski, JC; Chapin, SJ | 1 |
| Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 1 |
| Jakubík, J; Tucek, S | 1 |
| Dupont, C; Frandsen, TP; Honzatko, RB; Lehmbeck, J; Sierks, MR; Stoffer, B; Svensson, B | 1 |
| Inao, S; Kuchiwaki, H; Sugita, K; Yamamoto, M; Yoshida, K | 1 |
| Chéramy, A; Desce, JM; Glowinski, J; Godeheu, G | 1 |
| Hata, K; Hiraga, A; Suzuki, Y; Tsuiki, S | 1 |
| Fuchs, JA; Hanson, C; Li, H; Thomas, GJ; Woodward, C | 1 |
| Sipos, L; von Heijne, G | 1 |
| Allende, CC; Allende, JE; Gatica, M; Hinrichs, MV; Jedlicki, A; Pongor, S; Tellez, R | 1 |
| Berelowitz, M; Bruno, JF; Song, J; Xu, Y | 1 |
| Chester-Jones, H; Davis, DL; Goodband, RD; Johnston, LJ; Pettigrew, JE; Rettmer, I; Rozeboom, DW; Rust, JW; Stevenson, JS; Tokach, MD | 1 |
| Albritton, LM; Malhotra, S; Scott, AG; Zavorotinskaya, T | 1 |
| Henderson, CG; Saha, S; Slepecky, NB | 1 |
| Job, D; Multigner, L; Pignot-Paintrand, I; Plessmann, U; Rüdiger, M; Saoudi, Y; Weber, K | 1 |
| Butt, HL; Dunstan, RH; Klineberg, IJ; McGregor, NR; Roberts, TK; Zerbes, M | 1 |
| Brugerolle, G; Delgado-Viscogliosi, P; Viscogliosi, E | 1 |
| Galbraith, SL; MacKay, KB; McCulloch, J; Patel, TR; Woodruff, GN | 1 |
| Bärtsch, P; Dröge, W; Edler, L; Fischbach, T; Friedmann, B; Hack, V; Kinscherf, R; Weiss, C | 1 |
| Ehrlich, SD; Noirot-Gros, MF | 1 |
| Dubus, A; Frère, JM; Lamotte-Brasseur, J; Ledent, P | 1 |
| Angkanaporn, K; Bryden, WL; Ravindran, V | 1 |
| Derkinderen, P; Girault, JA; Sasaki, T; Siciliano, JC; Toutant, M | 1 |
| Lanyi, JK; Needleman, R; Richter, HT | 1 |
| Far, DF; Loubat, A; Ponzio, G; Rezzonico, R; Rochet, N; Rossi, B | 1 |
| Misu, Y; Miyamae, T; Ueda, H; Yue, JL | 1 |
| Chiu, SY; Choi, I | 1 |
| Alexander, P; Antosiewicz, J; Bryan, P; Gilson, M; Khare, D; Orban, J | 1 |
| Kirsch, JF; Luo, J; Park, Y; Schultz, PG | 1 |
| Chance, MR; Friedman, JM; Goldberg, DE; Huang, S; Kloek, AP; Miller, LM; Peterson, ES; Vidugiris, G; Wang, J; Wittenberg, JB | 1 |
| Petersen, BO; Shuman, S; Wittschieben, J | 1 |
| Hatanaka, H; Numakawa, T; Ogura, A; Sakai, N; Yamada, M | 1 |
| Beverung, CJ; Blanch, HW; Radke, CJ | 1 |
| Chasteen, ND; Grady, JK; He, QY; MacGillivray, RT; Mason, AB; Tam, BM; Woodworth, RC | 1 |
| deMaré, F; Logan, DT; Nordlund, P; Persson, BO; Sjöberg, BM; Slaby, A | 1 |
| Ekberg, M; Nordlund, P; Pötsch, S; Sahlin, M; Sandin, E; Sjöberg, BM; Thunnissen, M | 1 |
| Lynch, MA; Mullany, PM | 1 |
| Edara, S; Goodtzova, K; Kanugula, S; Pegg, AE | 1 |
| Meneghini, C; Morante, S | 1 |
| Frankfurter, A; Redeker, V; Rossier, J | 1 |
| Arnold, E; Clark, AD; Das, K; Ding, J; Hsiou, Y; Hughes, SH; Kleim, JP; Riess, G; Rösner, M; Winkler, I | 1 |
| Munagala, NR; Wang, CC | 1 |
| Hanson, DK; Miksovska, J; Schiffer, M; Sebban, P; Valerio-Lepiniec, M | 1 |
| Behr, J; Grzybek, S; Hellwig, P; Ludwig, B; Mäntele, W; Michel, H | 1 |
| Sun, S; Toney, MD | 1 |
| Hashimoto, K; Kikuchi, A; Shirouzu, M; Yokoyama, S | 1 |
| Brady, K; Denton, G; Matteis, CI; Missailidis, S; Murray, A; Price, MR; Searle, MS; Spencer, DI; Tendler, SJ | 1 |
| Bauminger, ER; Harrison, PM; Nowik, I; Quail, MA; Treffry, A; Zhao, Z | 1 |
| Buse, G; Hellwig, P; Mäntele, W; Soulimane, T | 1 |
| Mine, Y; Zhang, JW | 1 |
| Bandyopadhyay, P; Craig, AG; Olivera, BM | 1 |
| Baykov, AA; Efimova, IS; Goldman, A; Lahti, R; Magretova, NN; Mikalahti, K; Parfenyev, AN; Salminen, A | 1 |
| Fujino, M; Nishizawa, M; Oguchi, T; Suzuki, K; Toh-e, A | 1 |
| Freeman, AL; Hadman, M; Pasquale, EB; Pazzagli, C; Ruoslahti, E; Schneller, M; Smith, JW; Zisch, AH | 1 |
| Boscá, L; Fernández, AP; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA; Olivenza, R; Rodrigo, J | 1 |
| Choi, G; Choi, KY; Ha, NC; Kim, DH; Kim, SW; Oh, BH; Park, S | 1 |
| Brown, LS; Lanyi, JK; Needleman, R | 1 |
| Aoudia, M; Guliaev, AB; Leontis, NB; Rodgers, MA | 1 |
| Blackshaw, S; Brat, DJ; Clements, EE; Conover, JR; Favit, A; Krug, DK; Pieper, AA; Pinto-Garcia, P; Snyder, SH; Verma, A; White, AJ | 1 |
| Lacount, MW; Lebioda, L; Lewinski, K; Ortlund, E | 1 |
| Anderson, CM; Chan, PH; Chen, Y; Copin, JC; Fahlman, CS; Stein, BA; Swanson, RA; Ying, W | 1 |
| Follows, BC; Hergenrother, PJ; Martin, SF; Trotter, BK | 1 |
| Benfenati, F; D'Antuono, M; D'Arcangelo, G; Giovedì, S; Onofri, F; Tancredi, V | 1 |
| Bonaccorsi di Patti, MC; Camuti, AP; Felice, MR; Lania, A; Musci, G | 1 |
| Alizon, M; Brelot, A; Heveker, N; Montes, M | 1 |
| Britt, RD; Campbell, KA; Debus, RJ; Hays, AM; Pham, DP | 1 |
| Pereira, MM; Teixeira, M; Verkhovskaya, ML; Verkhovsky, MI | 1 |
| Dragic, T; Guo, Y; Kajumo, F; Thompson, DA | 1 |
| Atwood, CS; Bush, AI; Huang, X; Khatri, A; Kim, YS; Moir, RD; Roher, AE; Scarpa, RC; Tanzi, RE | 1 |
| Li, Y; Wavak, D; Wolf, ME; Xue, CJ | 1 |
| Nakamoto, RK; Peskova, YB | 1 |
| Prakash, V; Rao, JV; Rao, NA; Savithri, HS | 1 |
| Bré, MH; Dallai, R; Levilliers, N; Mencarelli, C | 1 |
| Borisy, GG; Gundersen, GG; Infante, AS; Stein, MS; Zhai, Y | 1 |
| Gross, DJ; Holbrook, MR; Slakey, LL | 1 |
| Hagedorn, CH; Hodel, AE; Hodel, MR; Hsu, PC; Taylor, LJ; Thomas, JW | 1 |
| Grosse Berkhoff, E; Stöcker, W; Yiallouros, I | 1 |
| Beverley, PC; Flower, DR; Morgan, G; Tchilian, EZ; Wallace, DL; Wells, RS | 1 |
| Aertsen, A; Balzarini, J; Camarasa, MJ; De Clercq, E; Pelemans, H; Pérez-Pérez, MJ; San-Félix, A; Van Laethem, K; Vandamme, AM; Velázquez, S | 1 |
| Agrawal, A; Greenhough, TJ; Shrive, AK; Volanakis, JE | 1 |
| Konczal, D; McIntire, SL; Russnak, R | 1 |
| Dong , J; Gao, S; López, JA; McIntire, LV; Romo, GM; Schade, AJ; Turner, NT; Ye, P | 1 |
| Beernink, PT; Doyle, SA; Koshland, DE | 1 |
| Baciou, L; Ermler, U; Fritzsch, G; Kuglstatter, A; Michel, H | 1 |
| Hisatomi, O; Imamoto, Y; Kataoka, M; Koshimizu, H; Mihara, K; Mizukami, T; Tokunaga, F; Tsujimoto, K | 1 |
| Araki, S; Hayashi, M; Itoh, M; Kumada, S; Minagawa, M; Mizutani, T; Morimatsu, Y; Oda, M; Shioda, K; Tamagawa, K | 1 |
| Changchien, LM; Hardy, LW; Maley, F; Saxl, RL | 1 |
| Eisenberg, D; Gill, HS | 1 |
| Doroudchi, MM; Durham, HD; Figlewicz, DA; Minotti, S | 1 |
| Arimura, K; Eto, K; Fukuyama, N; Miyamoto, K; Moriguchi, S; Murao, K; Nakanishi, H; Osame, M; Wakamiya, J | 1 |
| Bagga, S; Batra, JK; Gaur, D; Nair, DT; Nayak, SK; Salunke, DM | 1 |
| Kawakami, M; Kozaki, S; Sato, K; Sekiguchi, M; Takahashi, M | 1 |
| Aoyagi, K; Kondo, S; Ohnishi, H; Ono, K; Takahashi, M; Yamamori, S | 1 |
| Abe, K; Hayashi, T; Manabe, Y; Murakami, T; Shoji, M; Wang, JM; Warita, H | 1 |
| Lewis, NG; Singh, S; Towers, GH | 1 |
| Hall, JW; Huang, Z; Liu, D; Luo, J; Luo, Z; Pomerantz, RJ; Zhou, N | 1 |
| Ahuja, N; Bhatnagar, R; Kumar, P | 1 |
| Cusanovich, MA; Devanathan, S; Lin, S; Tollin, G; Woodbury, N | 1 |
| Haeggström, JZ; Kull, F; Lind, B; Ohlson, E | 1 |
| Baumann, U; Hege, T | 1 |
| Cau, J; Comps, M; Delsert, C; Faure, S; Morin, N | 1 |
| Hampson, DR; Naples, M; Peltekova, V; Rosemond, E; Thøgersen, H | 1 |
| Aguilar, P; Arias-Montaño, JA; Méndez, JA; Millán, A; Ortega, A | 1 |
| Grehn, L; Gustafsson, A; Jemth, P; Mannervik, B; Pettersson, PL | 1 |
| Beyermann, M; Blomenröhr, M; Bogerd, J; Hund, E; Kühne, R; Leurs, R; ter Laak, T | 1 |
| Gundersen, GG; Lin, SX; Maxfield, FR | 1 |
| Chuang, DM; Hashimoto, R; Hough, C; Nakazawa, T; Yamamoto, T | 1 |
| Naumann, TA; Reznikoff, WS | 1 |
| Blomstrand, E; Essén-Gustavsson, B | 1 |
| Skafar, DF; Zhong, L | 1 |
| Ghisellini, P; Pinna, LA; Sarno, S | 1 |
| Akita, RW; Penuel, E; Sliwkowski, MX | 1 |
| Applebury, ML; Fasick, JI; Oprian, DD | 1 |
| Dayanir, V; Majnoun, F; Meyer, RD; Rahimi, N | 1 |
| Di Stasi, AM; Macchia, G; Mallozzi, C; Maura, G; Minetti, M; Petrucci, TC | 1 |
| Khanna, S; Roy, S; Sen, CK; Venojarvi, M | 1 |
| Bowery, NG; Richards, DA; Sgouros, S; Tolias, CM | 1 |
| Chow, H; Pi, J; Pittard, AJ | 1 |
| Allison, WS; Bandyopadhyay, S; Huynh, HG; Ren, H; Valder, CR | 1 |
| Allen, JP; Kálmán, L; LoBrutto, R; Narváez, AJ; Williams, JC | 1 |
| Adams, JA; Moore, MJ; Taylor, SS | 1 |
| Antosiewicz, JM; Briggs, JM; Bruix, M; Grimsley, GR; Huyghues-Despointes, BM; Laurents, DV; Newsom, S; Pace, CN; Rico, M; Schell, D; Scholtz, JM; Shaw, KL; Thurlkill, RL; Treviño, S | 1 |
| Barkley, SJ; Droogmans, L; Oudjama, Y; Poulter, CD; Stalon, V; Tricot, C; Wouters, J | 1 |
| Cai, S; Shang, M; Wang, X | 1 |
| Bauer, CR; Carlo, WA; Donovan, EF; Ehrenkranz, RA; Fanaroff, AA; Koch, MA; Korones, SB; Laptook, AR; Lemons, JA; Oh, W; Papile, LA; Poindexter, BB; Shankaran, S; Stevenson, DK; Stoll, BJ; Tyson, JE; Wright, LL | 1 |
| Anderson, VE; Atwood, CS; Carey, PR; Dong, J; Perry, G; Siedlak, SL; Smith, MA | 1 |
| Bhatnagar, A; Gray, JA; Gurevich, VV; Roth, BL | 1 |
| Aldred, S; Fitzgerald, M; Moore, KM; Waring, RH | 1 |
| Govindaswami, M; Hersh, LB; Thompson, MW | 1 |
| Beck, DO; Bukys, MA; Kalafatis, M; Singh, LS | 1 |
| Butt, HL; Dunstan, RH; Klineberg, IJ; McGregor, NR; Niblett, SH; Roberts, TK; Zerbes, M | 2 |
| FRIEDBERG, F; HAYDEN, GA | 1 |
| QUINTO, G | 1 |
| CIRCO, R; FREEMAN, BA | 1 |
| FEREN, CJ; HEDRICK, LR | 1 |
| GERULAT, BF; MAURER, PH; PINCHUCK, P | 1 |
| RIGBI, M; SELA, M | 1 |
| FASMAN, G; NORLAND, K; PESCE, A | 1 |
| BACQUES, C; WORBE, JF | 1 |
| BODENHEIMER, E; FASMAN, GD; LINDBLOW, C | 1 |
| OLSON, JC; PUNCH, JD; SCALETTI, JV | 1 |
| EDMAN, P; NIALL, H | 1 |
| Heinrichs, DE; Sebulsky, MT; Shilton, BH; Speziali, CD | 1 |
| Eckel, J; Rakatzi, I; Seipke, G | 1 |
| Amon, LM; Archambault, J; Cameron, DR; Coulombe, R; Fink, D; Massariol, MJ; Thauvette, L; Titolo, S; Wang, Y; Welchner, E; White, PW; Yoakim, C | 1 |
| Arce, CA; Barra, HS; Bisig, CG; Contín, MA; Purro, SA | 1 |
| Weber, K; Westermann, S | 1 |
| Dal Molin, F; Montecucco, C; Naletto, L; Romanello, V; Tonello, F | 1 |
| Huber, RE; Penner, RM; Roth, NJ | 1 |
| Draker, KA; Wright, GD | 1 |
| Eijsink, VG; Gåseidnes, S; Nielsen, JE; Synstad, B; Van Aalten, DM; Vriend, G | 1 |
| Chen, N; Li, B; Murphy, TH; Raymond, LA | 1 |
| Lai, CY; Lin, VS; Pruski, M; Radu, DR; Wiench, JW | 1 |
| ELVEHJEM, CA; SIRNY, RJ; VIOLANTE, AM | 1 |
| El-Mashtoly, SF; Fujiwara, K; Hamada, N; Imamoto, Y; Kataoka, M; Kumauchi, M; Sasaki, J; Tokunaga, F; Unno, M; Yamauchi, S | 1 |
| Atkins, WM; Hickey, MJ; Mahajan, S; Mehta, R; Nath, A; Pearson, JT; Sherman, DR | 1 |
| Anderson, SM; Kassenbrock, CK | 1 |
| Castro, C; Collinsová, M; Evans, JC; Garrow, TA; Gratson, AA; Jiracek, J; Ludwig, ML | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Jin, Y; Kitagawa, T; Nagai, M; Nagai, Y; Nagatomo, S | 1 |
| Hayashi, T; Huganir, RL | 1 |
| Escovar-Kousen, J; Irwin, DC; Wilson, DB; Zhou, W | 1 |
| Bohrer, D; de Carvalho, LM; do Nascimento, PC; Mendonça, JK; Polli, VG | 1 |
| Adachi, M; Hirata, A; Mikami, B; Utsumi, S | 1 |
| Croteau, DL; DellaVecchia, MJ; Kisker, C; Mandavilli, BS; Skorvaga, M; Theis, K; Truglio, JJ; Van Houten, B | 1 |
| Andresen, BS; Bross, P; Corydon, TJ; Engel, PC; Frazier, DM; Gregersen, N; Hansen, J; Kenney, JM; McCandless, SE; O'Reilly, L; Olpin, SE; Winter, V | 1 |
| Farhan, H; Freissmuth, M; Korkhov, VM; Sitte, HH | 1 |
| Inoue, Y; Ishihara, Y; Kawai, M; Rekharsky, MV; Yamamura, H | 1 |
| Allen, JP; LoBrutto, R; Narváez, AJ; Williams, JC | 1 |
| Ostrov, DA; Sandberg, EM; Sayeski, PP; VonDerLinden, D | 1 |
| Ballou, DP; Entsch, B; Ortiz-Maldonado, M | 1 |
| Böttcher, T; Bunkowski, S; Christen, S; Gerber, J; Goiny, M; Kuhnt, U; Lotz, M; Lykkesfeldt, J; Nau, R; Ren, H; Schau, I; Spreer, A; Werner, C | 1 |
| Akin, CD; Harris, WS; Isley, WL; Rosipal, S; Schonfeld, G; Yue, P | 1 |
| Agmon, N | 1 |
| Brown, DE; Dooley, DM; Knowles, PF; Kurtis, CR; McPherson, MJ; Mure, M; Phillips, SE; Rogers, MS; Saysell, C; Tambyrajah, WS; Wilmot, CM | 1 |
| Hensel, R; Lorentzen, E; Pohl, E; Siebers, B | 1 |
| Ding, Z; Francis, MB; Kovacs, EW; Schlick, TL | 1 |
| Huffman, HA; Lappe, JW; Patel, HN; Sniegowski, JA; Wachter, RM | 1 |
| Chambers, EJ; Haworth, IS; Katsamba, PS; Laird-Offringa, IA; Law, MJ | 1 |
| Agarwal, R; Binz, T; Swaminathan, S | 1 |
| Kajikawa, H; Kurihara, M; Mitsumori, M; Tajima, K | 1 |
| Hofmann, T; Stark, T | 1 |
| Peterson, BZ; Ponoran, TA; Ragsdale, DS; Rasmusson, RL; Wang, X | 1 |
| Jiang, X; Lipsky, RH; Marini, AM; Mearow, K; Okagaki, P; Tian, F | 1 |
| Black, S; Samols, D; Wilson, A | 1 |
| Breyer, RM; Hata, AN; Lybrand, TP | 1 |
| Kandori, H; Mogi, T; Nakamura, H; Yamazaki, Y | 1 |
| Edwards, RA; Glover, JN; Lee, MS; Thede, GL | 1 |
| Kannan, N; Neuwald, AF | 1 |
| Hewlins, MJ; John, RA; Markova, M; Peneff, C; Schirmer, T | 1 |
| Egebjerg, J; Gajhede, M; Geballe, MT; Holm, MM; Kastrup, JS; Naur, P; Traynelis, SF; Vestergaard, B | 1 |
| Halliwell, B; Hyun, DH; Jenner, P; Lee, M | 1 |
| Chaki, S; Craft, TK; DeVries, AC; Khanna, S; Notestine, MA; Parinandi, NL; Rink, C; Roy, S; Sen, CK; Slivka, A | 1 |
| Dubovaya, V; Efimov, A; Frolova, L; Justesen, J; Kisselev, L; Kolosov, P; Kononenko, A; Oparina, N; Seit-Nebi, A | 1 |
| Holden, HM; Martí-Arbona, R; Raushel, FM; Thoden, JB | 1 |
| González, MI; Robinson, MB; Sheldon, AL | 1 |
| Barre, A; Czjzek, M; Peumans, WJ; Receveur-Bréchot, V; Rougé, P; Roussel, A; Van Damme, EJ | 1 |
| Inagaki, C; Kitagawa, K; Otani, H; Wu, B; Xiong, ZM; Zhang, NY | 1 |
| Izaguirre, G; Olson, ST | 1 |
| Devi, RR; Vijayalakshmi, P | 1 |
| Partin, KM; Prescott, C; Staley, KJ; Weeks, AM | 1 |
| Lahav, M; Nicholson, GJ; Reiner, C; Schurig, V; Shavit, E; Weissbuch, I | 1 |
| Ioannidis, N; Petrouleas, V; Zahariou, G | 1 |
| Donnini, S; Groenhof, G; Juffer, AH; Wierenga, RK | 1 |
| Amorós, A; Carrato, A; Hernández, S; Kogevinas, M; Lloreta, J; López-Knowles, E; Malats, N; Real, FX; Serra, C; Tardón, A | 1 |
| Bryant, I; Fry, R; Gallo, RM; Riese, DJ; Williams, EE | 1 |
| Green, T; Nanao, MH; Nayeem, N; Zhang, Y | 1 |
| Gao, YG; Hu, HY; Ouyang, N; Xia, ZX | 1 |
| Antoine, M; Boschi-Muller, S; Branlant, G; Gand, A | 1 |
| Schwer, B; Shuman, S; Wang, LK | 1 |
| Chloë Bulinski, J; Eiserich, JP; Harper, RW; Kubala, L; Phung, AD; Soucek, K | 1 |
| Covian, R; Hellwig, P; Hunte, C; Macmillan, F; Meunier, B; Trumpower, BL; Wenz, T | 1 |
| Ayres, M; Li, S; Liu, J; Powers, JP; Sudom, A; Walker, NP; Wang, Z; Wesche, H | 1 |
| András, IE; Deli, MA; Hayashi, K; Hennig, B; Toborek, M; Veszelka, S | 1 |
| Cristòfol, R; García-Matas, S; Pertusa, M; Rodríguez-Farré, E; Sanfeliu, C | 1 |
| Böcker, U; Haas, SL; Ruether, A; Schreiber, S; Singer, MV | 1 |
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| Elsasser, TH; Garrett, WM; Kahl, S; Li, CJ; Rodrigo, J; Sartin, JL | 1 |
| Adayev, T; Bolton, DC; Chen-Hwang, MC; Hwang, YW; Lee, E; Murakami, N | 1 |
| Khanna, S; Park, HA; Roy, S; Sen, CK | 1 |
| Allen, RA; da Fonseca, PC; Duchesnes, C; Pease, JE; Williams, TJ; Wise, EL | 1 |
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| Cheng, CY; Kim, C; Saldanha, SA; Taylor, SS | 1 |
| Barycki, JJ; Boanca, G; Morrow, AL; Sand, A; Williams, K | 1 |
| Almeida, FC; Da Poian, AT; Juliano, L; Juliano, MA; Lima, CS; Sarzedas, CG; Valente, AP | 1 |
| Cane, DE; Christianson, DW; Jiang, J; Vedula, LS; Zakharian, T | 1 |
| Allis, CD; Duncan, EM; Fischle, W; Li, H; Liang, L; Murakami-Ishibe, S; Patel, DJ; Wang, W | 1 |
| Dennis, DM; Glushakov, AV; Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Yarotskyy, V | 1 |
| Deamer, D; Shinitzky, M | 1 |
| Metlitzky, M; Puehringer, S; Schwarzenbacher, R | 1 |
| Battaglia, A; Cibert-Goton, V; Gavazzi, I; Slack, S | 1 |
| Du, CP; Gao, J; Hou, XY; Liu, Y; Qi, J; Tai, JM; Wang, W | 1 |
| Alvestad Linger, RM; Browning, MD; Davies, KD; Freund, RK; Goebel-Goody, SM | 1 |
| Banerjee, SR; Barinka, C; Byun, Y; Castanares, M; Chen, Y; Dusich, CL; Kozikowski, AP; Lubkowski, J; Mease, RC; Pomper, MG | 1 |
| Holyavka, MG; Kovaleva, TA; Kozhedub, SV; Rezvan, SG | 1 |
| Englander, EW; Greeley, GH; Lee, HM; Reed, J | 1 |
| Chupakhin, VI; Osolodkin, DI; Palyulin, VA; Zefirov, NS | 1 |
| Cook, KE; Dall'acqua, WF; Damschroder, MM; Oganesyan, V; Woods, RM; Wu, H | 1 |
| Oomens, J; Redlich, B; Steill, JD | 1 |
| Arnett, SO; Raber, ML; Townsend, CA | 1 |
| Faria, TQ; Gerbelová, H; Maçanita, AL; Noronha, M; Rudolph, R; Sampaio, MM; Santos, H | 1 |
| Bolger, MB; Davies, DL; Haworth, IS; Kulkarni, AA; Xu, L | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Jiang, ZL; Liang, AH; Liang, YY; Liu, QY | 1 |
| Cui, S; Gu, X; Liu, Y; Ma, Z; Wu, X | 1 |
| Alesutan, I; Dërmaku-Sopjani, M; Föller, M; Fraser, S; Kemp, BE; Lang, F; Sopjani, M | 1 |
| Chardwiriyapreecha, S; Iwaki, T; Kakinuma, Y; Mukaiyama, H; Sekito, T; Takegawa, K | 1 |
| Dementiev, A; Gettins, PG; Huang, X; Olson, ST | 1 |
| Chen, J; Ghosh, K; Gibb, B; Gupta, K; Sharp, R; Van Duyne, GD | 1 |
| Kuroda, H; Kuroda, M; Saito, K; Suzuki, Y | 1 |
| Blanchard, JS; Hegde, SS; Vetting, MW | 1 |
| Culka, A; Edwards, HG; Jehlička, J | 1 |
| Kang, S; Poo, H; Ryu, SE; Yoon, SW | 1 |
| Besnard, A; Caboche, J; Girault, JA; Heck, N; Hervé, D; Pagès, C; Pascoli, V; Vanhoutte, P | 1 |
| Aronowski, J; Grotta, JC; Savitz, SI; Sharma, S; Xi, X; Yang, B | 1 |
| Chang, WL; Cheng, HC; Sheu, BS; Wu, JJ; Yang, HB; Yeh, YC | 1 |
| Gudasheva, TA; Klodt, PM; Kudrin, VS; Narkevich, VB; Ostrovskaia, RU; Shubenina, EV | 1 |
| Clarke, DT; Davis, PJ; Gunčar, G; Jelinska, C; Kenig, M; Kokalj, SJ; Staniforth, RA; Turk, D; Turk, V; Waltho, JP; Zerovnik, E | 1 |
| Cross, MC; Haynie, DT; Khadka, DB | 1 |
| Byers, SW; Khamis, ZI; Kirilyuk, A; Pompach, P; Sahab, ZJ; Sung, Y; Zhang, L | 1 |
| Auerochs, S; Marschall, M; Milbradt, J; Muller, YA; Sevvana, M; Sticht, H | 1 |
| Arai, S; Blaber, M; Kurihara, K; Kuroki, R; Morimoto, S; Shoyama, Y; Takeuchi, A; Tamada, T; Taura, F | 1 |
| Bartolini, F; Gundersen, GG; Ramalingam, N | 1 |
| Chung, SH; Hilder, TA | 1 |
| Meng, Q; Quirion, R; Sun, C; Wang, H; Zhang, L; Zheng, W | 1 |
| Gustafsson, MO; Hamasy, A; Hussain, A; Mohamed, AJ; Mohammad, DK; Nore, BF; Smith, CI; Uslu, M | 1 |
| Shichida, Y; Yamashita, T; Yanagawa, M | 1 |
| Brooks, IM; Chowdhury, D; Haucke, V; Marco, S; Pérez-Otaño, I; Rao, Y; Tavalin, SJ; Wesseling, JF; Zandueta, A | 1 |
| Klerman, H; Levine, E; McClendon, CL; Rapp, C | 1 |
| Afanador, L; Angulo, JA; Baker, L; Diaz, C; Mexhitaj, I; Ordonez, D | 1 |
| Bardhi, E; Dagostino, C; Gliozzi, M; Ilari, S; Lauro, F; Mollace, V; Muscoli, C; Palma, E; Salvemini, D | 1 |
| Benninghoff, J; Dölzer, AL; Geiger, J; Genius, J; Giegling, I; Hartmann, AM; Möller, HJ; Rujescu, D | 1 |
| Cuniasse, P; Dive, V; Nagase, H; Stura, EA; Visse, R | 1 |
| Bermek, O; Grindley, ND; Joyce, CM | 1 |
| Bennetts, B; Parker, MW | 1 |
| Bhattacharya, B; Chatterjee, M; Choudhuri, S; Chowdhury, IH; Dutta, D; Kundu, S; Mandal, LK; Mitra, B; Sen, A | 1 |
| Ola, MS | 1 |
| Cui, HJ; Li, Y; Liu, JH; Lu, Y; Wang, H; Wang, Y; Yang, R | 1 |
| Cesaro, L; Donella-Deana, A; Marin, O; Pinna, LA; Venerando, A | 1 |
| Garnham, CP; Lee, DY; Roll-Mecak, A; Vemu, A | 1 |
| Rice, LM; Sirajuddin, M; Vale, RD | 1 |
| Borejdo, J; Maji, S; Valapala, M; Vishwanatha, JK | 1 |
| Coskuner, O; Wise, O | 1 |
| Avila, C; Cañas, RA; Cánovas, FM; de la Torre, F; Pascual, MB | 1 |
| Bramwell, RC; Donato, AJ; Enz, RA; Hart, CR; Hazra, S; Henson, GD; Layec, G; Lesniewski, LA; Morgan, RG; Reihl, KD; Richardson, RS; Trinity, JD; Walker, AE | 1 |
| Janke, C | 1 |
| Chow, DC; Gilbert, HF; Hu, L; Palzkill, T; Prasad, BV; Sankaran, B; Stojanoski, V | 1 |
| Bystrowska, B; Gaweł, M; Holst, B; Librowski, T; Młyniec, K; Reczyński, W | 1 |
| Jiang, ZL; Li, TS; Liang, AH; Luo, YH; Wen, GQ; Ye, LL | 1 |
| Hall, K; Lewitt, M; Melkersson, K | 1 |
| Bacher-Stier, C; Berndt, M; Bullich, S; Chin, FT; Dinkelborg, LM; Fels, LM; Friebe, M; Gambhir, SS; Gekeler, V; Hoehne, A; Iagaru, AH; Keu, KV; Koglin, N; Kumar, M; Mittra, ES; Moon, DH; Mosci, C; Mueller, A; Schmitt-Willich, H; Stephens, AW | 1 |
| Asensio, MJ; García-Sanz, P; Herranz, AS; Moratalla, R; Solís, O | 1 |
| Barbosa, RM; Dias, C; Ferreiro, E; Laranjinha, J; Ledo, A; Lourenço, CF | 1 |
| Bi, K; Chen, X; Gu, L; Hou, C; Shi, H; Xing, H; Zhang, M; Zhao, L | 1 |
| Assar, Z; Borhan, B; Geiger, JH; Kramer, K; McCornack, C; Nossoni, Z; Santos, EM; Vasileiou, C; Wang, W | 1 |
| Clatterbuck-Soper, SF; Jackrel, ME; Mili, S; Shorter, J; Yasuda, K | 1 |
| Choi, MH; Chung, BC; Hong, J; Lee, W; Park, NH; Shin, HJ | 1 |
| Bansal, A; Ghosh, AS; Kar, D; Kumar, NG; Matcha, A; Nathan, S; Pandey, SD | 1 |
| Abate, ML; Bugianesi, E; Buzzigoli, E; Carli, F; Cassader, M; Ciociaro, D; Della Latta, V; Gaggini, M; Gambino, R; Gastaldelli, A; Marietti, M; Rosso, C | 1 |
| Chang, YC; Cheng, HC; Chiang, YC; Hong, SR; Hsu, N; Huang, WE; Huang, YS; Inoue, T; Lin, CY; Lin, YC; Pusapati, GV; Rohatgi, R; Shaner, NC; Wang, CL | 1 |
| Lockridge, O; Schopfer, LM | 2 |
| Green, ME; Kariev, AM | 1 |
| Eaton-Rye, JJ; Kovács, S; Morris, JN; Summerfield, TC; Vass, I | 1 |
| Balakrishnan, A; Bhat, M; Joshi, MB; Kotambail, A; Pai, S; Satyamoorthy, K; Sharma, P | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Andrade, CMB; Chenet, AL; de Almeida, FJS; de Oliveira, MR; Duarte, AR | 1 |
| Kim, UJ; Lee, BH; Lee, KH | 1 |
| Beebe, K; Boysen, M; Bruce, JE; Chavez, JD; Gelis, I; Keramisanou, D; Lu, Y; Mayer, MP; Neckers, L; Prodromou, C; Trepel, JB; Xu, W; Zuehlke, AD | 1 |
| Kang, GY; Kim, KP; Lee, JW; Lee, N; Park, SH | 1 |
| Dotsikas, Y; Loukas, YL; Manta-Vogli, PD; Schulpis, KH | 1 |
| Alqhazo, M; Rashaid, AB | 1 |
| Cui, C; Drennan, CL; Greene, BL; Kang, G; Nocera, DG; Stubbe, J | 1 |
| Hammes-Schiffer, S; Reinhardt, CR; Zhong, J | 1 |
| Karakawa, S; Kawasaki, M; Mine, T; Nishitani, S; Sato, W; Shindo, D; Somekawa, S; Suzuki, K; Toyoda, S; Umeda, K | 1 |
| Caparco, AA; González-Gamboa, I; McCaskill, JM; Steinmetz, NF | 1 |
| Bedi, S; Haag, A; Mudgal, R; Ono, A | 1 |
| DI, LQ; Huang, X; Lu, YY; Luo, ZC; Qi, MY; Shan, JJ; Zhang, W | 1 |
| Jia, W; Shi, L; Wang, X | 1 |
| Guo, J; Guo, Z; Lian, X; Wang, H | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Hellmann, A; Korczynska, J; Mika, A; Taciak, A; Turyn, J; Zwara, A | 1 |
6 review(s) available for tyrosine and glutamic acid
| Article | Year |
|---|---|
Post-translationally modified neuropeptides from Conus venoms.
Topics: Amino Acid Sequence; Animals; Glutamic Acid; Ion Channels; Isomerism; Molecular Sequence Data; Mollusk Venoms; Neuropeptides; Protein Processing, Post-Translational; Snails; Tyrosine | 1999 |
Post-translational modifications regulate microtubule function.
Topics: Acetylation; Animals; Glutamic Acid; Glycine; Microtubules; Models, Molecular; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Quaternary; Tubulin; Tyrosine | 2003 |
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
Topics: Animals; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydroxyl Radical; Mental Disorders; Neuroprotective Agents; Phenylalanine; Synaptic Transmission; Tyrosine | 2006 |
Plastidic aspartate aminotransferases and the biosynthesis of essential amino acids in plants.
Topics: Amino Acids, Essential; Aspartate Aminotransferases; Aspartic Acid; Chloroplasts; Glutamic Acid; Ketoglutaric Acids; Models, Biological; Oxaloacetic Acid; Phylogeny; Plant Proteins; Plants; Plastids; Substrate Specificity; Tyrosine | 2014 |
The tubulin code: molecular components, readout mechanisms, and functions.
Topics: Acetylation; Eukaryota; Glutamic Acid; Glycine; Microtubule-Associated Proteins; Microtubules; Protein Isoforms; Protein Processing, Post-Translational; Tubulin; Tyrosine | 2014 |
Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggregates.
Topics: Acetylcholinesterase; Animals; Glutamic Acid; Humans; Lysine; Molecular Weight; Neuroblastoma; Organophosphorus Compounds; Pesticides; Proteins; Rabbits; Tyrosine | 2023 |
5 trial(s) available for tyrosine and glutamic acid
| Article | Year |
|---|---|
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1987 |
Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass in healthy individuals: the effect of N-acetyl-cysteine.
Topics: Acetylcysteine; Adult; Aerobiosis; Anaerobiosis; Body Weight; Cachexia; Cystine; Exercise; Female; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Tyrosine | 1996 |
Effect of exercise on concentrations of free amino acids in pools of type I and type II fibres in human muscle with reduced glycogen stores.
Topics: Adult; Amino Acids; Exercise; Glutamic Acid; Glycogen; Histocytochemistry; Humans; Lactic Acid; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Tyrosine | 2002 |
Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infants.
Topics: Amino Acids; Ammonia; Female; Glutamic Acid; Glutamine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Very Low Birth Weight; Male; Nutritional Requirements; Parenteral Nutrition; Phenylalanine; Safety; Tyrosine | 2003 |
Effects of Five Amino Acids (Serine, Alanine, Glutamate, Aspartate, and Tyrosine) on Mental Health in Healthy Office Workers: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial.
Topics: Adult; Aged; Alanine; Amino Acids; Aspartic Acid; Double-Blind Method; Glutamic Acid; Humans; Mental Fatigue; Mental Health; Middle Aged; Occupational Health; Serine; Treatment Outcome; Tyrosine; Young Adult | 2022 |
368 other study(ies) available for tyrosine and glutamic acid
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
The A14 position of insulin tolerates considerable structural alterations with modest effects on the biological behavior of the hormone.
Topics: Adipose Tissue; Alanine; Amino Acids; Animals; Cattle; Cycloleucine; Glucose; Glutamates; Glutamic Acid; Histidine; Insulin; Lipids; Liver; Lysine; Phenylalanine; Rats; Receptor, Insulin; Sheep; Structure-Activity Relationship; Swine; Tyrosine | 1992 |
Structural origin of the immunological diversity of two closely related tetrapeptides: CIDNP study of TyrTyrGluGlu and TyrGluTyrGlu epitopes.
Topics: Amino Acid Sequence; Epitopes; Glutamates; Glutamic Acid; Immunochemistry; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Photochemistry; Protein Conformation; Tyrosine | 1992 |
Microtubules in the fission yeast Schizosaccharomyces pombe contain only the tyrosinated form of alpha-tubulin.
Topics: Amino Acid Sequence; Blotting, Western; Cell Cycle; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Glutamates; Glutamic Acid; Microscopy, Fluorescence; Microtubules; Molecular Sequence Data; Schizosaccharomyces; Tubulin; Tyrosine | 1991 |
Tyrosine 70 fine-tunes the catalytic efficiency of aspartate aminotransferase.
Topics: Aspartate Aminotransferases; Aspartic Acid; Enzyme Inhibitors; Escherichia coli; Glutamates; Glutamic Acid; Isotopes; Ketoglutaric Acids; Kinetics; Maleates; Mutation; N-Methylaspartate; Spectrophotometry; Tyrosine | 1991 |
Use of high performance liquid chromatography in defining the abnormalities in the free amino acid patterns in the cerebrospinal fluid of patients with aseptic meningitis.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Meningitis, Aseptic; Middle Aged; Phenylalanine; Tyrosine | 1991 |
Stimulation of protein tyrosine phosphorylation by NMDA receptor activation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Immunoblotting; Kinetics; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1991 |
Plasma GABA-like activity in rats with hepatic encephalopathy is due to GABA and taurine.
Topics: Animals; Binding, Competitive; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine; Tyrosine | 1990 |
Protein tyrosine kinase activity and its substrates in rat intestinal microvillus membranes.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cell Division; Electrophoresis, Polyacrylamide Gel; Female; Glutamates; Glutamic Acid; Intestinal Mucosa; Male; Microvilli; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Tyrosine | 1990 |
Stimulatory actions of bioflavonoids on tyrosine uptake into cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Biological Transport; Carbon Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chamomile; Flavones; Flavonoids; Glutamates; Glutamic Acid; Histidine; Lysine; Oils, Volatile; Plants, Medicinal; Quercetin; Serine; Tyrosine | 1990 |
Escherichia coli maltodextrin phosphorylase: contribution of active site residues glutamate-637 and tyrosine-538 to the phosphorolytic cleavage of alpha-glucans.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Escherichia coli; Glucans; Glucosyltransferases; Glutamates; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid; Tyrosine | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
The glutamate-mediated release of dopamine in the rat striatum: further characterization of the dual excitatory-inhibitory function.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Bicuculline; Caudate Nucleus; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Kinetics; Quinoxalines; Rats; Rats, Inbred Strains; Reference Values; Tetrodotoxin; Tritium; Tyrosine | 1990 |
Random tyrosine and glutamic acid-containing polymers are very powerful inhibitors of casein kinase-2.
Topics: Casein Kinases; Glutamates; Glutamic Acid; Kinetics; Molecular Weight; Polymers; Protein Kinase Inhibitors; Tyrosine | 1989 |
The utilization of nitrogen for growth in mice fed blends of purified proteins.
Topics: Amino Acids; Animals; Blood Urea Nitrogen; Caseins; Dietary Proteins; Gelatin; Gliadin; Glutamates; Glutamic Acid; Glycine; Lactalbumin; Male; Mice; Nitrogen; Phenylalanine; Tyrosine; Weaning; Weight Gain; Zein | 1989 |
Effects of stretching and disuse on amino acids in muscles of rat hind limbs.
Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Denervation; Female; Glutamates; Glutamic Acid; Glutamine; Hindlimb; Immobilization; Muscle Contraction; Muscles; Rats; Rats, Inbred Strains; Tyrosine | 1989 |
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Some observations on conserved polar side chains in immunoglobulin V-domains.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Immunoglobulin Variable Region; Protein Conformation; Threonine; Tyrosine | 1989 |
A protein-free diet changes synaptosomal membrane fluidity and tyrosine and glutamate transport.
Topics: Animals; Brain Chemistry; Dietary Proteins; Glutamates; Glutamic Acid; Male; Membrane Fluidity; Membrane Proteins; N-Acetylneuraminic Acid; Rats; Rats, Inbred Strains; Sialic Acids; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Tyrosine | 1989 |
Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A.
Topics: Binding Sites; Carboxypeptidases; Carboxypeptidases A; Glutamates; Glutamic Acid; Hydrogen Bonding; Phenylalanine; Protein Conformation; Tyrosine; Water; X-Ray Diffraction; Zinc | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Synthesis and characterization of six sequential polypeptides containing tyrosine, glutamic acid, alanine, and glycine by circular dichroism and difference spectroscopy.
Topics: Alanine; Circular Dichroism; Glutamates; Glutamic Acid; Glycine; Peptides; Protein Conformation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tyrosine | 1985 |
[Amino acid uptake and release by colorectal cancer in man].
Topics: Aged; Amino Acids; Colonic Neoplasms; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Male; Middle Aged; Ornithine; Rectal Neoplasms; Tyrosine | 1986 |
In vivo inhibition of tyrosine uptake into rat retina by large neutral but not acidic amino acids.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Aspartic Acid; Binding, Competitive; Biological Transport; Brain; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Male; Rats; Rats, Inbred Strains; Retina; Tyrosine | 1986 |
Engineering of the active site of human lysozyme: conversion of aspartic acid 53 to glutamic acid and tyrosine 63 to tryptophan or phenylalanine.
Topics: Amino Acid Sequence; Aspartic Acid; Chitin; Genetic Engineering; Glutamates; Glutamic Acid; Humans; Micrococcus; Muramidase; Mutation; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Tyrosine | 1987 |
Specificity of tyrosine protein kinases of the structurally related receptors for insulin and insulin-like growth factor I: Tyr-containing synthetic polymers as specific inhibitors or substrates.
Topics: Alanine; Biopolymers; Glutamates; Glutamic Acid; Humans; Insulin-Like Growth Factor I; Phosphorylation; Placenta; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Somatomedin; Somatomedins; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1988 |
Effects of amino acid substitutions at the active site in Escherichia coli beta-galactosidase.
Topics: Amino Acids; Bacteriophages; beta-Galactosidase; Binding Sites; Escherichia coli; Galactosidases; Glutamates; Glutamic Acid; Histidine; Methionine; Mutation; Plasmids; Restriction Mapping; Substrate Specificity; Tyrosine | 1988 |
Variations in aortal elastin composition after atherogenic diet feeding in rats. Possible involvement of two different elastin types.
Topics: Amino Acids; Animals; Aorta; Arginine; Aspartic Acid; Diet, Atherogenic; Elastin; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Tyrosine | 1982 |
The function of vitamin A.
Topics: Animals; Arginine; Aspartic Acid; Bacteriorhodopsins; Biological Transport; Cell Differentiation; Cell Nucleus; Glutamates; Glutamic Acid; Halorhodopsins; Humans; Lysine; Ocular Physiological Phenomena; Rhodopsin; Tyrosine; Vitamin A | 1983 |
Effect of aspartame loading on plasma and erythrocyte free amino acid concentrations in one-year-old infants.
Topics: Adult; Age Factors; Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Erythrocytes; Glutamates; Glutamic Acid; Humans; Infant; Phenylalanine; Tyrosine | 1983 |
Abnormal amino acid concentrations in plasma and urine of experimentally diabetic dogs.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glutamates; Glutamic Acid; Histidine; Male; Phenylalanine; Renal Aminoacidurias; Tryptophan; Tyrosine | 1983 |
Interstrain conservation of the murine GAT-specific antibody V kappa repertoire as analyzed at the germline gene level.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Cloning, Molecular; DNA; Genes; Glutamates; Glutamic Acid; Hybridomas; Immunoglobulin kappa-Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; RNA, Messenger; Species Specificity; Tyrosine | 1983 |
Defect in phosphorylation of insulin receptors in cells from an insulin-resistant patient with normal insulin binding.
Topics: Caseins; Female; Glutamates; Glutamic Acid; Humans; Insulin; Insulin Resistance; Monocytes; Phosphorylation; Protein Kinases; Receptor, Insulin; Syndrome; Tyrosine | 1984 |
Presynaptic binding of amino acids: characterization of the binding and dissociation properties of taurine, GABA, glutamate, tyrosine and norleucine.
Topics: Aminocaproates; Animals; Brain; Carbon Radioisotopes; Cattle; Cell Membrane; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Norleucine; Receptors, Neurotransmitter; Synapses; Taurine; Tritium; Tyrosine | 1983 |
Glutamic acid and glutamine levels in serum and cerebrospinal fluid in hepatic encephalopathy.
Topics: Adult; Aged; Ammonia; Female; Glutamates; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged; Tyrosine | 1984 |
Depolarization and neurotransmitters increase neuronal protein tyrosine phosphorylation.
Topics: Animals; Calcium; Cells, Cultured; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Neurotransmitter Agents; Phosphorylation; Phosphotyrosine; Potassium Chloride; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine | 1994 |
Changes in the tyrosine phosphorylation of mitogen-activated protein kinase in the rat hippocampus during and following severe hypoglycemia.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Electroencephalography; Glutamic Acid; Hippocampus; Hypoglycemia; Immunoblotting; Insulin; Male; Molecular Weight; Phosphorylation; Phosphotyrosine; Rats; Rats, Wistar; Tyrosine | 1994 |
A cyclin-dependent kinase homologue, p130PITSLRE is a phosphotyrosine-independent SH2 ligand.
Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinases; Cell Line; Chromatography, Affinity; Cloning, Molecular; DNA, Complementary; Glutamic Acid; Humans; Ligands; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins pp60(c-src); RNA; Sequence Homology, Amino Acid; Serine; Tyrosine | 1994 |
Monoclonal anti-dipeptide antibodies cross-react with detyrosinated and glutamylated forms of tubulins.
Topics: Animals; Antibodies, Monoclonal; Cattle; CHO Cells; Cilia; Cricetinae; Cross Reactions; Dipeptides; Epitopes; Flagella; Fluorescent Antibody Technique; Glutamic Acid; Male; Mice; Microtubules; Sea Urchins; Sperm Tail; Tubulin; Tyrosine | 1995 |
Activity of the MAP kinase ERK2 is controlled by a flexible surface loop.
Topics: Amino Acid Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Crystallization; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine; Mitogen-Activated Protein Kinase 1; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Conformation; Protein Serine-Threonine Kinases; Structure-Activity Relationship; Tyrosine | 1995 |
Blood urea and amino acid concentrations in pigs of two breed combinations as affected by energy intakes.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Crosses, Genetic; Diet; Energy Intake; Energy Metabolism; Glutamic Acid; Histidine; Lysine; Male; Swine; Tyrosine; Weight Gain | 1995 |
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
Topics: Amino Acid Sequence; Binding Sites; Glutamates; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Phosphopeptides; Protein Conformation; Proto-Oncogene Proteins pp60(c-src); Sequence Alignment; Tyrosine; X-Ray Diffraction | 1993 |
Inhibitory effect of fluoride on insulin receptor autophosphorylation and tyrosine kinase activity.
Topics: Adenosine Triphosphate; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Fluorides; Glutamates; Glutamic Acid; Humans; Male; Phosphorylation; Phosphotyrosine; Placenta; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptor, IGF Type 1; Receptor, Insulin; Sodium Fluoride; Tyrosine | 1993 |
Amino acid residues that influence the binding of manganese or calcium to photosystem II. 1. The lumenal interhelical domains of the D1 polypeptide.
Topics: Amino Acids; Aspartic Acid; Calcium; Cyanobacteria; Electron Transport; Glutamic Acid; Histidine; Light; Light-Harvesting Protein Complexes; Manganese; Mutagenesis, Site-Directed; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plastoquinone; Protein Structure, Secondary; Spectrometry, Fluorescence; Structure-Activity Relationship; Tyrosine | 1995 |
Macromolecular recognition through electrostatic repulsion.
Topics: Biological Evolution; Geobacillus stearothermophilus; Glutamic Acid; Macromolecular Substances; Point Mutation; RNA, Transfer, Phe; RNA, Transfer, Tyr; RNA, Transfer, Val; Substrate Specificity; Transfer RNA Aminoacylation; Tyrosine; Tyrosine-tRNA Ligase | 1995 |
Mutations in two specific residues of testicular angiotensin-converting enzyme change its catalytic properties.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; HeLa Cells; Humans; Kinetics; Lisinopril; Lysine; Male; Mutagenesis; Peptidyl-Dipeptidase A; Phenylalanine; Point Mutation; Rabbits; Recombinant Proteins; Substrate Specificity; Testis; Transfection; Tyrosine; Vaccinia virus | 1993 |
Dissecting differential binding in the forward and reverse reaction of Escherichia coli maltodextrin phosphorylase using 2-deoxyglucosyl substrates.
Topics: Amino Acid Sequence; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Deoxyglucose; Escherichia coli; Glucans; Glucosyltransferases; Glutamates; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Polysaccharides, Bacterial; Recombinant Proteins; Substrate Specificity; Tyrosine | 1994 |
Role of alpha and beta carboxyl-terminal residues in the kinetics of human oxyhemoglobin dimer assembly.
Topics: Amino Acid Sequence; Arginine; Genetic Variation; Glutamates; Glutamic Acid; Heme; Hemoglobin A; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Oxyhemoglobins; Point Mutation; Spectrophotometry; Tyrosine; Valine | 1994 |
Rat osteoblasts and ROS 17/2.8 cells contain a similar protein tyrosine phosphatase.
Topics: Animals; Animals, Newborn; Cells, Cultured; Chromatography, Ion Exchange; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Osteoblasts; Osteosarcoma; Phosphorylation; Polymers; Protein Tyrosine Phosphatases; Rats; Sodium Chloride; Temperature; Tumor Cells, Cultured; Tyrosine | 1993 |
Cellular microtubules heterogeneous in their content of microtubule-associated protein 4 (MAP4).
Topics: Animals; Antibodies; Cell Line; Chlorocebus aethiops; Fluorescent Antibody Technique; Glutamates; Glutamic Acid; HeLa Cells; Humans; Microtubule-Associated Proteins; Microtubules; Neurites; Protein Binding; Tubulin; Tumor Cells, Cultured; Tyrosine | 1994 |
Opposite presynaptic regulations by glutamate through NMDA receptors of dopamine synthesis and release in rat striatal synaptosomes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Deaminase; Animals; Body Water; Dopamine; Dopamine Agents; Ergolines; Glutamates; Glutamic Acid; In Vitro Techniques; Ionomycin; Male; Models, Biological; Neostriatum; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synaptosomes; Tyrosine | 1994 |
Protection by alcuronium of muscarinic receptors against chemical inactivation and location of the allosteric binding site for alcuronium.
Topics: Acetylcholine; Alcuronium; Allosteric Site; Animals; Aspartic Acid; Atropine; Carbachol; Choline; Cholinergic Agents; Female; Gallamine Triethiodide; Glutamic Acid; Heart Atria; Male; Parasympatholytics; Rats; Rats, Wistar; Receptors, Muscarinic; Tyrosine | 1994 |
Site-directed mutagenesis of the catalytic base glutamic acid 400 in glucoamylase from Aspergillus niger and of tyrosine 48 and glutamine 401, both hydrogen-bonded to the gamma-carboxylate group of glutamic acid 400.
Topics: Aspergillus niger; Base Sequence; Carboxylic Acids; Catalysis; DNA Primers; Enzyme Stability; Glucan 1,4-alpha-Glucosidase; Glutamic Acid; Glutamine; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Thermodynamics; Tyrosine | 1994 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats; Electroencephalography; Evoked Potentials; Freezing; Glutamic Acid; Methionine; Motor Cortex; Phenylalanine; Serine; Synaptic Transmission; Tyrosine; Valine | 1994 |
Presynaptic control of dopamine synthesis and release by excitatory amino acids in rat striatal synaptosomes.
Topics: Animals; Binding, Competitive; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; Glutamic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptosomes; Tritium; Tyrosine; Water | 1994 |
Identification of a rat liver protein-tyrosine phosphatase similar to human placental PTPase-1B using quantitatively phosphorylated protein substrates.
Topics: Animals; Anion Exchange Protein 1, Erythrocyte; Glutamates; Glutamic Acid; Humans; Liver; Microtubule-Associated Proteins; Phosphorylation; Placenta; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Substrate Specificity; Tubulin; Tyrosine | 1993 |
Determination of the pKa values of active-center cysteines, cysteines-32 and -35, in Escherichia coli thioredoxin by Raman spectroscopy.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Solutions; Spectrum Analysis, Raman; Thioredoxins; Tryptophan; Tyrosine | 1993 |
Predicting the topology of eukaryotic membrane proteins.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Membrane Proteins; Tryptophan; Tyrosine | 1993 |
Activity of recombinant alpha and beta subunits of casein kinase II from Xenopus laevis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinase II; Cloning, Molecular; DNA; Escherichia coli; Glutamates; Glutamic Acid; Glutathione Transferase; Molecular Sequence Data; Oligopeptides; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Tyrosine; Xenopus laevis | 1993 |
Regulation of hypothalamic preprogrowth hormone-releasing factor messenger ribonucleic acid expression in food-deprived rats: a role for histaminergic neurotransmission.
Topics: Animals; Dietary Proteins; Food Deprivation; Gene Expression Regulation; Glutamates; Glutamic Acid; Growth Hormone-Releasing Hormone; Histamine; Histidine; Histidine Decarboxylase; Hypothalamus; Male; Methylhistidines; Neurotransmitter Agents; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tryptophan; Tyrosine | 1993 |
Failure of dietary amino acid supplementation at weaning to influence reproductive traits of sows.
Topics: Amino Acids; Animal Feed; Animals; Estrus; Female; Fetal Death; Food, Fortified; Glutamates; Glutamic Acid; Litter Size; Ovulation; Parity; Phenylalanine; Pregnancy; Reproduction; Swine; Tyrosine; Weaning | 1993 |
Analysis of the murine ecotropic leukemia virus receptor reveals a common biochemical determinant on diverse cell surface receptors that is essential to retrovirus entry.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Line; Glutamic Acid; Humans; Leukemia Virus, Murine; Membrane Glycoproteins; Membrane Proteins; Mice; Molecular Sequence Data; Peptide Fragments; Receptors, Virus; Tyrosine | 1996 |
Post-translational modifications of tubulin suggest that dynamic microtubules are present in sensory cells and stable microtubules are present in supporting cells of the mammalian cochlea.
Topics: Acetylation; Animals; Antibodies, Monoclonal; Antibody Specificity; Cerebellum; Cochlea; Cytoplasm; Gerbillinae; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Immunoblotting; Microtubules; Polymers; Protein Processing, Post-Translational; Tubulin; Tyrosine; Vestibular Nucleus, Lateral | 1995 |
The A and B tubules of the outer doublets of sea urchin sperm axonemes are composed of different tubulin variants.
Topics: Amino Acid Sequence; Animals; Glutamic Acid; Male; Microscopy, Fluorescence; Molecular Sequence Data; Protein Processing, Post-Translational; Sea Urchins; Sequence Homology, Amino Acid; Sperm Tail; Spermatozoa; Tubulin; Tyrosine | 1996 |
Preliminary determination of a molecular basis of chronic fatigue syndrome.
Topics: Aconitic Acid; Adolescent; Adult; Alanine; Amino Acids; Analysis of Variance; beta-Alanine; Biomarkers; Fatigue Syndrome, Chronic; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Humans; Male; Middle Aged; Multivariate Analysis; Physical Examination; Pyrrolidines; Reference Values; Succinates; Succinic Acid; Surveys and Questionnaires; Tyrosine | 1996 |
Tubulin post-translational modifications in the primitive protist Trichomonas vaginalis.
Topics: Acetylation; Animals; Antibodies, Monoclonal; Antibody Specificity; Glutamic Acid; Humans; Microtubules; Protein Processing, Post-Translational; Trichomonas vaginalis; Tubulin; Tyrosine | 1996 |
The relationship between glutamate release and cerebral blood flow after focal cerebral ischaemia in the cat: effect of pretreatment with enadoline (a kappa receptor agonist).
Topics: Animals; Anti-Arrhythmia Agents; Benzofurans; Blood Glucose; Body Temperature; Brain Ischemia; Cats; Cerebrovascular Circulation; Female; gamma-Aminobutyric Acid; Glutamic Acid; Microdialysis; Pyrrolidines; Receptors, Opioid, kappa; Stereotaxic Techniques; Tyrosine | 1996 |
Change of a catalytic reaction carried out by a DNA replication protein.
Topics: Bacteriophage phi X 174; Binding Sites; DNA Helicases; DNA Replication; DNA-Binding Proteins; DNA, Bacterial; DNA, Single-Stranded; DNA, Viral; Esterification; Evolution, Molecular; Glutamic Acid; Hydrolysis; Mutation; Plasmids; Proteins; Trans-Activators; Tyrosine; Viral Proteins | 1996 |
The roles of residues Tyr150, Glu272, and His314 in class C beta-lactamases.
Topics: beta-Lactamases; Binding Sites; Catalysis; Enzyme Stability; Glutamic Acid; Histamine; Hydrogen-Ion Concentration; Hydrolysis; Mutagenesis, Site-Directed; Tyrosine | 1996 |
Additivity of apparent and true ileal amino acid digestibilities in soybean meal, sunflower meal, and meat and bone meal for broilers.
Topics: Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Biological Products; Chickens; Digestion; Female; Glutamic Acid; Glycine max; Helianthus; Homoarginine; Ileum; Isoleucine; Meat; Minerals; Predictive Value of Tests; Serine; Tyrosine | 1996 |
Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus.
Topics: Animals; Cell Adhesion Molecules; Enzyme Activation; Excitatory Amino Acid Agonists; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine | 1996 |
Perturbed interaction between residues 85 and 204 in Tyr-185-->Phe and Asp-85-->Glu bacteriorhodopsins.
Topics: Aspartic Acid; Bacteriorhodopsins; Darkness; Glutamic Acid; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Recombinant Proteins; Spectrophotometry; Tyrosine | 1996 |
Interleukin 6 stimulates a tyrosine kinase activity potentially involved in mouse hybridoma cell growth.
Topics: Adenosine; Animals; Cell Division; Cytosol; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Hybridomas; Interleukin-6; Mice; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1997 |
Altered basal release and pressor effect of L-DOPA in the rostral ventrolateral medulla of spontaneously hypertensive rats.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Dopamine Agents; Glutamic Acid; Heart Rate; Hypertension; Levodopa; Male; Medulla Oblongata; Microdialysis; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrodotoxin; Tyrosine; Tyrosine 3-Monooxygenase | 1995 |
Abolition of substrate-dependent currents by tyrosine mutation in the transmembrane domain of glutamate transporter.
Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Carrier Proteins; Electric Conductivity; Electrophysiology; Glutamic Acid; Glycoproteins; Immunohistochemistry; Membrane Glycoproteins; Mutagenesis, Site-Directed; Mutation; Oocytes; Rats; Recombinant Proteins; Tyrosine; Xenopus | 1997 |
pKa measurements from nuclear magnetic resonance for the B1 and B2 immunoglobulin G-binding domains of protein G: comparison with calculated values for nuclear magnetic resonance and X-ray structures.
Topics: Aspartic Acid; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Immunoglobulin G; Lysine; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Protein Conformation; Protein Kinases; Substrate Specificity; Tyrosine | 1997 |
Noncoded amino acid replacement probes of the aspartate aminotransferase mechanism.
Topics: Alanine; Amino Acids; Arginine; Aspartate Aminotransferases; Aspartic Acid; Escherichia coli; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Mutation; Protein Biosynthesis; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Transcription, Genetic; Tyrosine | 1997 |
A comparison of functional and structural consequences of the tyrosine B10 and glutamine E7 motifs in two invertebrate hemoglobins (Ascaris suum and Lucina pectinata).
Topics: Amino Acid Substitution; Animals; Ascaris suum; Binding Sites; Bivalvia; Carbon Monoxide; Carboxyhemoglobin; Glutamic Acid; Heme; Hemoglobins; Kinetics; Oxyhemoglobins; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; Tyrosine | 1997 |
Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease.
Topics: Binding Sites; Cysteine; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Endonucleases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis; Structure-Activity Relationship; Tyrosine; Vaccinia virus | 1998 |
BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Indole Alkaloids; Isoenzymes; Male; Microscopy, Confocal; Neuronal Plasticity; Neurons; Neuroprotective Agents; Periodicity; Phospholipase C gamma; Phosphorylation; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Synapses; Type C Phospholipases; Tyrosine | 1997 |
Adsorption dynamics of L-glutamic acid copolymers at a heptane/water interface.
Topics: Adsorption; Alanine; Circular Dichroism; Glutamic Acid; Heptanes; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Isoelectric Point; Leucine; Molecular Conformation; Phenylalanine; Polymers; Surface Properties; Surface Tension; Tyrosine | 1998 |
Mutations at nonliganding residues Tyr-85 and Glu-83 in the N-lobe of human serum transferrin. Functional second shell effects.
Topics: Base Sequence; Copper; DNA Primers; Electron Spin Resonance Spectroscopy; Glutamic Acid; Humans; Hydrogen Bonding; Iron; Ligands; Mutation; Protein Binding; Transferrin; Tyrosine | 1998 |
Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants: structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins.
Topics: Alanine; Apoenzymes; Catalysis; Crystallization; Crystallography, X-Ray; Ferrous Compounds; Glutamic Acid; Hydroxylation; Iron; Models, Molecular; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Ribonucleotide Reductases; Tyrosine | 1998 |
Preserved catalytic activity in an engineered ribonucleotide reductase R2 protein with a nonphysiological radical transfer pathway. The importance of hydrogen bond connections between the participating residues.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Escherichia coli; Free Radicals; Glutamic Acid; Hydrogen Bonding; Iron; Protein Binding; Protein Engineering; Ribonucleotide Reductases; Tyrosine | 1998 |
Evidence for a role for synaptophysin in expression of long-term potentiation in rat dentate gyrus.
Topics: Animals; Dentate Gyrus; Electric Stimulation; Enzyme Inhibitors; Glutamic Acid; Long-Term Potentiation; Male; Perforant Pathway; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Synapses; Synaptophysin; Tyrosine; Tyrphostins | 1998 |
Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
Topics: Alanine; Amino Acid Sequence; DNA Repair; DNA-Binding Proteins; Enzyme Activation; Glutamic Acid; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Threonine; Tyrosine | 1998 |
The active site structure of tetanus neurotoxin resolved by multiple scattering analysis in X-Ray absorption spectroscopy.
Topics: Absorptiometry, Photon; Animals; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Histidine; Metalloendopeptidases; Neurotoxins; Tetanus Toxin; Thermolysin; Tyrosine; Zinc | 1998 |
Posttranslational modifications of the C-terminus of alpha-tubulin in adult rat brain: alpha 4 is glutamylated at two residues.
Topics: Amino Acid Sequence; Animals; Brain; Glutamic Acid; Isomerism; Molecular Sequence Data; Peptide Fragments; Protein Processing, Post-Translational; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin; Tyrosine | 1998 |
Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance.
Topics: Antiviral Agents; Crystallography, X-Ray; Drug Design; Drug Resistance; Glutamic Acid; Glycine; HIV Reverse Transcriptase; Leucine; Models, Molecular; Molecular Conformation; Mutation; Quinoxalines; Reverse Transcriptase Inhibitors; Tyrosine | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Mutations in the environment of the primary quinone facilitate proton delivery to the secondary quinone in bacterial photosynthetic reaction centers.
Topics: Alanine; Benzoquinones; Cytochrome c Group; Electron Transport; Glutamic Acid; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenotype; Photolysis; Photosynthetic Reaction Center Complex Proteins; Protons; Rhodobacter capsulatus; Tyrosine | 1999 |
Electrochemical and ultraviolet/visible/infrared spectroscopic analysis of heme a and a3 redox reactions in the cytochrome c oxidase from Paracoccus denitrificans: separation of heme a and a3 contributions and assignment of vibrational modes.
Topics: Arginine; Aspartic Acid; Electrochemistry; Electron Transport Complex IV; Glutamic Acid; Heme; Molecular Conformation; Oxidation-Reduction; Paracoccus denitrificans; Porphyrins; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tyrosine | 1999 |
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
Topics: Alanine Racemase; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Geobacillus stearothermophilus; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Protons; Pyridoxal Phosphate; Schiff Bases; Solvents; Tyrosine | 1999 |
Double-mutant analysis of the interaction of Ras with the Ras-binding domain of RGL.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Histidine; Humans; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; ras Proteins; Rats; Recombinant Fusion Proteins; Static Electricity; Tyrosine | 1999 |
Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Aspartic Acid; Binding, Competitive; Circular Dichroism; Epitopes; Glutamic Acid; Glycopeptides; Glycosylation; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mucin-1; Peptide Fragments; Protein Denaturation; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Thermodynamics; Titrimetry; Tryptophan; Tyrosine | 1999 |
Stages in iron storage in the ferritin of Escherichia coli (EcFtnA): analysis of Mössbauer spectra reveals a new intermediate.
Topics: Alanine; Dimerization; Escherichia coli; Ferric Compounds; Ferritins; Ferrous Compounds; Freezing; Glutamic Acid; Humans; Iron; Iron Isotopes; Mutagenesis, Site-Directed; Phenylalanine; Spectroscopy, Mossbauer; Tyrosine | 1999 |
Electrochemical, FTIR, and UV/VIS spectroscopic properties of the ba(3) oxidase from Thermus thermophilus.
Topics: Arginine; Aspartic Acid; Buffers; Cytochrome b Group; Deuterium Oxide; Electrochemistry; Electron Transport Complex IV; Glutamic Acid; Heme; Lysine; Oxidation-Reduction; Peptides; Phosphates; Porphyrins; Potentiometry; Propionates; Protein Conformation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thermus thermophilus; Tyrosine; Water | 1999 |
Characterization of residues in human IgE and IgG binding site by chemical modification of ovomucoid third domain.
Topics: Acylation; Alkylation; Aspartic Acid; Binding Sites; Child, Preschool; Circular Dichroism; Female; Glutamic Acid; Histidine; Humans; Immunoglobulin E; Immunoglobulin G; Infant; Lysine; Ovomucin; Protein Structure, Secondary; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1999 |
Reciprocal effects of substitutions at the subunit interfaces in hexameric pyrophosphatase of Escherichia coli. Dimeric and monomeric forms of the enzyme.
Topics: Amino Acid Substitution; Aspartic Acid; Catalysis; Crystallography, X-Ray; Dimerization; Enzyme Stability; Escherichia coli; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnesium Compounds; Protein Structure, Quaternary; Pyrophosphatases; Substrate Specificity; Temperature; Tyrosine | 1999 |
The Pho85 kinase, a member of the yeast cyclin-dependent kinase (Cdk) family, has a regulation mechanism different from Cdks functioning throughout the cell cycle.
Topics: Amino Acid Motifs; Amino Acid Sequence; Base Sequence; Cell Cycle; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Fungal Proteins; Gene Dosage; Gene Expression Regulation, Fungal; Glutamic Acid; Molecular Sequence Data; Multigene Family; Phosphorylation; Protein Binding; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tyrosine | 1999 |
Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses.
Topics: 3T3 Cells; Actins; Amino Acid Substitution; Animals; Cell Size; Conserved Sequence; COS Cells; Enzyme Activation; Glutamic Acid; Humans; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutagenesis; Phenylalanine; Phosphorylation; Protein Binding; Receptor Protein-Tyrosine Kinases; Receptor, EphB2; src Homology Domains; src-Family Kinases; Tyrosine | 2000 |
Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex.
Topics: Animals; Blotting, Western; Calcium; Cerebral Cortex; Chronic Disease; Glutamic Acid; Immunohistochemistry; L-Lactate Dehydrogenase; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Synaptosomes; Tyrosine | 2000 |
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Asparagine; Aspartic Acid; Binding Sites; Catalysis; Equilenin; Glutamic Acid; Hydrogen Bonding; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Nandrolone; Pseudomonas putida; Steroid Isomerases; Tyrosine | 2000 |
Origins of deuterium kinetic isotope effects on the proton transfers of the bacteriorhodopsin photocycle.
Topics: Arginine; Aspartic Acid; Bacteriorhodopsins; Deuterium Oxide; Glutamic Acid; Halobacterium salinarum; Kinetics; Mutagenesis, Site-Directed; Photolysis; Protons; Purple Membrane; Tyrosine; Water | 2000 |
Self-assembled complexes of oligopeptides and metalloporphyrins: measurements of the reorganization and electronic interaction energies for photoinduced electron-transfer reactions.
Topics: Electrons; Glutamic Acid; Metalloporphyrins; Models, Molecular; Molecular Conformation; Oligopeptides; Photochemistry; Protein Conformation; Thermodynamics; Tryptophan; Tyrosine | 2000 |
Poly(ADP-ribosyl)ation basally activated by DNA strand breaks reflects glutamate-nitric oxide neurotransmission.
Topics: Animals; Autoradiography; Brain; Cells, Cultured; DNA Damage; Enzyme Activation; Glutamic Acid; Immunohistochemistry; Kidney; Mice; Mice, Knockout; N-Methylaspartate; NAD; Nitric Oxide; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Proteins; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2000 |
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
Topics: Amidohydrolases; Aminolevulinic Acid; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diazooxonorleucine; Electrons; Enzyme Inhibitors; Glutamic Acid; Glutamine; Pseudomonas; Threonine; Tyrosine | 2000 |
Differing effects of copper,zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins.
Topics: Animals; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Gene Expression Regulation, Enzymologic; Glutamic Acid; Humans; Hydrazines; Kainic Acid; Mice; Mice, Transgenic; N-Methylaspartate; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Reactive Oxygen Species; Spermine; Superoxide Dismutase; Tyrosine; Vitamin K | 2000 |
The choline binding site of phospholipase C (Bacillus cereus): insights into substrate specificity.
Topics: Amino Acid Substitution; Bacillus cereus; Binding Sites; Catalysis; Choline; Glutamic Acid; Hydrolysis; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Recombinant Proteins; Substrate Specificity; Type C Phospholipases; Tyrosine | 2000 |
Interleukin-6 inhibits neurotransmitter release and the spread of excitation in the rat cerebral cortex.
Topics: Animals; Antigens, CD; Cerebral Cortex; Cytokine Receptor gp130; DNA-Binding Proteins; Dose-Response Relationship, Drug; Exocytosis; Glutamic Acid; Infrared Rays; Interleukin-6; Membrane Glycoproteins; Microscopy, Video; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Presynaptic Terminals; Rats; Rats, Wistar; STAT3 Transcription Factor; Synapsins; Synaptic Transmission; Synaptosomes; Trans-Activators; Tyrosine | 2000 |
The essential role of Glu-185 and Tyr-354 residues in the ferroxidase activity of Saccharomyces cerevisiae Fet3.
Topics: Catalysis; Ceruloplasmin; Glutamic Acid; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Tyrosine | 2000 |
Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities.
Topics: Amino Acid Sequence; Anti-HIV Agents; Antibodies, Monoclonal; Aspartic Acid; Binding Sites; Binding, Competitive; Chemokine CXCL12; Chemokines, CXC; Glutamic Acid; HIV Envelope Protein gp120; HIV-1; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Receptors, CXCR4; Recombinant Proteins; Signal Transduction; Static Electricity; Tyrosine | 2000 |
Glutamate 189 of the D1 polypeptide modulates the magnetic and redox properties of the manganese cluster and tyrosine Y(Z) in photosystem II.
Topics: Amino Acid Substitution; Catalysis; Electron Spin Resonance Spectroscopy; Electron Transport; Glutamic Acid; Kinetics; Manganese; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Protein Conformation; Recombinant Proteins; Tyrosine | 2000 |
The caa(3) terminal oxidase of Rhodothermus marinus lacking the key glutamate of the D-channel is a proton pump.
Topics: Amino Acid Sequence; Copper; Cytochrome c Group; Electron Transport Complex IV; Glutamic Acid; Gram-Negative Aerobic Bacteria; Heme; Liposomes; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Protein Conformation; Proteolipids; Proton Pumps; Sequence Alignment; Sequence Homology, Amino Acid; Tyrosine | 2000 |
Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4.
Topics: Amino Acid Sequence; Aspartic Acid; Glutamic Acid; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, CXCR4; Tyrosine | 2000 |
Copper catalyzed oxidation of Alzheimer Abeta.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Arginine; Catalysis; Chromatography, High Pressure Liquid; Copper; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Peroxide; Iron; Oxidation-Reduction; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Time Factors; Tyrosine | 2000 |
Amphetamine increases glutamate efflux in the rat ventral tegmental area by a mechanism involving glutamate transporters and reactive oxygen species.
Topics: Amino Acid Transport System X-AG; Amphetamine; Animals; ATP-Binding Cassette Transporters; Behavior, Animal; Calcium; Central Nervous System Stimulants; Cyclic N-Oxides; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Phenylalanine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine; Ventral Tegmental Area | 2000 |
Catalytic control and coupling efficiency of the Escherichia coli FoF1 ATP synthase: influence of the Fo sector and epsilon subunit on the catalytic transition state.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Biological Transport; Catalysis; Cysteine; Detergents; Dimethylamines; Enzyme Activation; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Proton-Translocating ATPases; Protons; Tyrosine | 2000 |
The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
Topics: Alanine; Amino Acid Substitution; Animals; Apoenzymes; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Cytosol; Formaldehyde; Glutamic Acid; Glycine Hydroxymethyltransferase; Humans; Kinetics; Liver; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Rabbits; Recombinant Fusion Proteins; Serine; Sheep; Structure-Activity Relationship; Tetrahydrofolates; Tyrosine | 2000 |
Accessory tubules and axonemal microtubules of Apis mellifera sperm flagellum differ in their tubulin isoform content.
Topics: Acetylation; Animals; Bees; Glutamic Acid; Glycosylation; Insect Proteins; Male; Microscopy, Immunoelectron; Microtubules; Protein Isoforms; Protein Processing, Post-Translational; Sarcosine; Sperm Tail; Tubulin; Tyrosine; Urea | 2000 |
Detyrosinated (Glu) microtubules are stabilized by an ATP-sensitive plus-end cap.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Chlorocebus aethiops; Cytoskeleton; Epithelial Cells; Glutamic Acid; Kidney; Microtubules; Protein Processing, Post-Translational; Tubulin; Tyrosine | 2000 |
Thermodynamic mixing of molecular states of the epidermal growth factor receptor modulates macroscopic ligand binding affinity.
Topics: Animals; CHO Cells; Cricetinae; Cytosol; ErbB Receptors; Glutamic Acid; Humans; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Phorbol Esters; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Thermodynamics; Tumor Cells, Cultured; Tyrosine | 2000 |
Structural requirements for the specific recognition of an m7G mRNA cap.
Topics: Amino Acid Substitution; Circular Dichroism; Eukaryotic Initiation Factor-4E; Flavins; Glutamic Acid; Guanosine; Hydrogen Bonding; Mutagenesis, Site-Directed; Peptide Initiation Factors; Phenylalanine; RNA Caps; RNA, Messenger; Spectrometry, Fluorescence; Static Electricity; Tryptophan; Tyrosine; Vaccinia virus; Viral Proteins | 2000 |
The roles of Glu93 and Tyr149 in astacin-like zinc peptidases.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Escherichia coli; Glutamic Acid; Kinetics; Metalloendopeptidases; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Renaturation; Recombinant Proteins; Tyrosine; Zinc | 2000 |
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Female; Fibronectins; Glutamic Acid; Humans; Infant; Leukocyte Common Antigens; Mice; Molecular Sequence Data; Polymorphism, Genetic; Protein Structure, Tertiary; Sequence Deletion; Severe Combined Immunodeficiency; Transfection; Tumor Cells, Cultured; Tyrosine | 2001 |
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine | 2001 |
Topology and structure of the C1q-binding site on C-reactive protein.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; C-Reactive Protein; Complement Activation; Complement C1q; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylcholine; Polysaccharides, Bacterial; Serum Albumin, Bovine; Streptococcus pneumoniae; Threonine; Tyrosine | 2001 |
A family of yeast proteins mediating bidirectional vacuolar amino acid transport.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Biological Transport; Carrier Proteins; Fluorescent Antibody Technique, Indirect; Fungal Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Membranes; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Anion Transporters; Phylogeny; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Tyrosine; Vacuoles | 2001 |
Tyrosine sulfation of glycoprotein I(b)alpha. Role of electrostatic interactions in von Willebrand factor binding.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cell Adhesion; Cell Line; Crotalid Venoms; Glutamic Acid; Hemagglutinins; Humans; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Platelet Glycoprotein GPIb-IX Complex; Protein Structure, Secondary; Recombinant Proteins; Ristocetin; Stress, Mechanical; Transfection; Tyrosine; von Willebrand Factor | 2001 |
Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Freezing; Glutamic Acid; Isocitrate Dehydrogenase; Macromolecular Substances; Magnesium; Malates; NADP; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2001 |
X-ray structure analyses of photosynthetic reaction center variants from Rhodobacter sphaeroides: structural changes induced by point mutations at position L209 modulate electron and proton transfer.
Topics: Amino Acid Substitution; Binding Sites; Computer Simulation; Crystallography, X-Ray; Electron Transport; Energy Transfer; Genetic Variation; Glutamic Acid; Models, Molecular; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Point Mutation; Proline; Protons; Quinones; Rhodobacter sphaeroides; Tyrosine | 2001 |
Roles of amino acid residues near the chromophore of photoactive yellow protein.
Topics: Amino Acids; Bacterial Proteins; Glutamic Acid; Halorhodospira halophila; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Photolysis; Photoreceptors, Microbial; Protons; Spectrophotometry; Threonine; Titrimetry; Tyrosine | 2001 |
Oxidative stress and disturbed glutamate transport in hereditary nucleotide repair disorders.
Topics: Adolescent; Adult; Aldehydes; Amino Acid Transport System X-AG; ATP-Binding Cassette Transporters; Biological Transport; Child; Cockayne Syndrome; DNA Repair; Female; Glutamic Acid; Glycation End Products, Advanced; Humans; Immunohistochemistry; Male; Neuroglia; Neurons; Oxidative Stress; Proteins; Tyrosine; Xeroderma Pigmentosum | 2001 |
Parameters affecting the restoration of activity to inactive mutants of thymidylate synthase via subunit exchange: further evidence that thymidylate synthase is a half-of-the-sites activity enzyme.
Topics: Alanine; Arginine; Binding Sites; Dimerization; Enzyme Activation; Escherichia coli; Ethanol; Ethylene Glycol; Glutamic Acid; Glycerol; Hydrogen-Ion Concentration; Peptide Fragments; Solutions; Temperature; Thymidylate Synthase; Tyrosine; Urea | 2001 |
The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Topics: Aminobutyrates; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; Electrons; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Models, Molecular; Salmonella typhimurium; Spectroscopy, Fourier Transform Infrared; Static Electricity; Substrate Specificity; Thallium; Tyrosine | 2001 |
Nitrotyrosination contributes minimally to toxicity of mutant SOD1 associated with ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Survival; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Glutamic Acid; Humans; Mice; Motor Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Superoxide Dismutase; Tyrosine | 2001 |
Involvement of enhanced sensitivity of N-methyl-D-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Proteins; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Membrane Glycoproteins; Mercury Poisoning, Nervous System; Methylmercury Compounds; Nerve Degeneration; Neurons; Nitrates; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2001 |
Mechanism of specific target recognition and RNA hydrolysis by ribonucleolytic toxin restrictocin.
Topics: Allergens; Animals; Antigens, Plant; Arginine; Circular Dichroism; Escherichia coli; Fungal Proteins; Glutamic Acid; HeLa Cells; Histidine; Humans; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Mycotoxins; Protein Synthesis Inhibitors; Rabbits; Recombinant Proteins; Reticulocytes; Ribonucleases; RNA, Ribosomal, 28S; Substrate Specificity; Tyrosine | 2001 |
Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia.
Topics: Animals; Botulinum Toxins; Botulinum Toxins, Type A; Cell Death; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Exocytosis; Glutamic Acid; Hippocampus; Immunoblotting; Ischemia; Janus Kinase 2; Neurons; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Erythropoietin; Time Factors; Tyrosine | 2001 |
A src family tyrosine kinase inhibits neurotransmitter release from neuronal cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Size; Cells, Cultured; Cerebellum; Cytoskeletal Proteins; Dopamine; Focal Adhesion Kinase 2; Gene Expression; Glutamic Acid; Humans; Neurons; Oncogene Protein pp60(v-src); Paxillin; PC12 Cells; Phalloidine; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Wistar; src-Family Kinases; Thiazoles; Thiazolidines; Tyrosine | 2001 |
Expressions of nitrotyrosine and TUNEL immunoreactivities in cultured rat spinal cord neurons after exposure to glutamate, nitric oxide, or peroxynitrite.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Central Nervous System Diseases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radicals; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Interneurons; Motor Neurons; Nerve Degeneration; Neurons; Neurotoxins; Nitrates; Nitric Oxide Donors; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spinal Cord; Tyrosine | 2001 |
Nitrogen recycling during phenylpropanoid metabolism in sweet potato tubers.
Topics: Ammonium Chloride; Darkness; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Indans; Light; Magnetic Resonance Spectroscopy; Nitrogen; Nitrogen Isotopes; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Stems; Quaternary Ammonium Compounds; Solanaceae; Time Factors; Tyrosine | 1998 |
Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies.
Topics: Aspartic Acid; Calcium; Cell Line; Chemokines; Flow Cytometry; Genes, Reporter; Glutamic Acid; HIV-1; Humans; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, CXCR4; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Structure-Activity Relationship; Tyrosine | 2001 |
Purification of anthrax edema factor from Escherichia coli and identification of residues required for binding to anthrax protective antigen.
Topics: Adenylyl Cyclases; Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Escherichia coli; Exotoxins; Gene Expression; Glutamic Acid; Glycine; Isoleucine; Lysine; Receptors, Peptide; Recombinant Fusion Proteins; Tyrosine; Valine | 2001 |
Early photocycle kinetic behavior of the E46A and Y42F mutants of photoactive yellow protein: femtosecond spectroscopy.
Topics: Alanine; Bacterial Proteins; Glutamic Acid; Halorhodospira halophila; Hydrogen Bonding; Kinetics; Light; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Photoreceptors, Microbial; Spectrophotometry; Tyrosine | 2001 |
Saccharomyces cerevisiae leukotriene A4 hydrolase: formation of leukotriene B4 and identification of catalytic residues.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Epoxide Hydrolases; Escherichia coli; Glutamic Acid; Humans; Hydrolysis; Leukotriene A4; Leukotriene B4; Leukotrienes; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Saccharomyces cerevisiae; Spodoptera; Tyrosine; Zinc | 2001 |
Protease C of Erwinia chrysanthemi: the crystal structure and role of amino acids Y228 and E189.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Caseins; Catalysis; Conserved Sequence; Crystallography, X-Ray; Dickeya chrysanthemi; Enzyme Activation; Enzyme Stability; Glutamic Acid; Hydrolysis; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Serine Endopeptidases; Tyrosine | 2001 |
A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization.
Topics: Actin Cytoskeleton; Actins; Animals; Catalytic Domain; cdc42 GTP-Binding Protein; Cell Line; Cloning, Molecular; Epithelial Cells; Gene Expression Regulation, Enzymologic; Glutamic Acid; Green Fluorescent Proteins; Indicator Dilution Techniques; Indicators and Reagents; Luminescent Proteins; Microtubules; Molecular Sequence Data; p21-Activated Kinases; Polymers; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; rac1 GTP-Binding Protein; Sequence Homology, Amino Acid; Transfection; Tyrosine; Xenopus laevis; Xenopus Proteins | 2001 |
Molecular determinants of high affinity binding to group III metabotropic glutamate receptors.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Immunoblotting; Immunohistochemistry; Ligands; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Metabotropic Glutamate; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2002 |
Glutamate activates PP125(FAK) through AMPA/kainate receptors in Bergmann glia.
Topics: Animals; Antibodies; Cell Adhesion; Cell Differentiation; Cells, Cultured; Cerebellum; Chick Embryo; Cytoskeleton; Dose-Response Relationship, Drug; Focal Adhesion Protein-Tyrosine Kinases; Glutamic Acid; Immunoblotting; Neuroglia; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Receptors, AMPA; Receptors, Kainic Acid; Signal Transduction; Tyrosine | 2001 |
Role of the glutamyl alpha-carboxylate of the substrate glutathione in the catalytic mechanism of human glutathione transferase A1-1.
Topics: Binding Sites; Carboxylic Acids; Catalysis; Dinitrochlorobenzene; Glutamic Acid; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oligopeptides; Protein Binding; Substrate Specificity; Tyrosine | 2001 |
Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Catfishes; Cell Line; Cell Membrane; Chickens; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Gonadotropin-Releasing Hormone; Humans; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Structure, Tertiary; Receptors, LHRH; Recombinant Fusion Proteins; Transfection; Tryptophan; Tyrosine | 2002 |
Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin.
Topics: Animals; Antibodies; Cell Compartmentation; Cell Line; Cell Membrane; Centrioles; CHO Cells; Cricetinae; Endocytosis; Fluorescent Antibody Technique; Glutamic Acid; HeLa Cells; Humans; Kinesins; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Protein Transport; Transferrin; Transport Vesicles; Tyrosine | 2002 |
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.
Topics: Animals; Antimanic Agents; Calcium; Cells, Cultured; Cerebral Cortex; Cytoprotection; Dose-Response Relationship, Drug; Glutamic Acid; Ion Transport; Lithium; Neurons; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors; Tyrosine; Valproic Acid | 2002 |
Tn5 transposase active site mutants.
Topics: Arginine; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; DNA, Bacterial; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Conformation; Transposases; Tyrosine | 2002 |
Mutations of tyrosine 537 in the human estrogen receptor-alpha selectively alter the receptor's affinity for estradiol and the kinetics of the interaction.
Topics: Animals; Cell Line; Crystallography, X-Ray; DNA, Complementary; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Glutamic Acid; Humans; Hydrogen Bonding; Insecta; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Phenylalanine; Protein Binding; Protein Conformation; Receptors, Estrogen; Serine; Time Factors; Transfection; Tyrosine | 2002 |
Unique activation mechanism of protein kinase CK2. The N-terminal segment is essential for constitutive activity of the catalytic subunit but not of the holoenzyme.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Casein Kinase II; Catalysis; Catalytic Domain; Enzyme Activation; Glutamic Acid; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Temperature; Tyrosine | 2002 |
Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association.
Topics: Amino Acid Motifs; Amino Acids; Animals; COS Cells; Dimerization; Glutamic Acid; Humans; K562 Cells; Ligands; Mutation; Phosphorylation; Precipitin Tests; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptor, ErbB-2; Time Factors; Transcriptional Activation; Transfection; Tyrosine; Valine | 2002 |
Spectral tuning in the mammalian short-wavelength sensitive cone pigments.
Topics: Amino Acid Substitution; Animals; Cattle; Glutamic Acid; Light; Mice; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Rod Opsins; Species Specificity; Spectrum Analysis; Transducin; Tyrosine; Ultraviolet Rays | 2002 |
The presence of a single tyrosine residue at the carboxyl domain of vascular endothelial growth factor receptor-2/FLK-1 regulates its autophosphorylation and activation of signaling molecules.
Topics: Animals; Blotting, Western; DNA, Complementary; Endothelium, Vascular; Enzyme Activation; Glutamic Acid; Isoenzymes; Ligands; MAP Kinase Signaling System; Mice; Mutagenesis, Site-Directed; Phenylalanine; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; src-Family Kinases; Swine; Time Factors; Type C Phospholipases; Tyrosine | 2002 |
Peroxynitrite affects exocytosis and SNARE complex formation and induces tyrosine nitration of synaptic proteins.
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Exocytosis; Fluorescent Dyes; Glutamic Acid; Macromolecular Substances; Male; Membrane Proteins; Munc18 Proteins; Nerve Tissue Proteins; Peroxynitrous Acid; Proteins; Rats; Rats, Sprague-Dawley; SNARE Proteins; Sodium Bicarbonate; Sodium Dodecyl Sulfate; Synaptosomal-Associated Protein 25; Synaptosomes; Tyrosine; Vesicular Transport Proteins | 2002 |
Glutamate-induced c-Src activation in neuronal cells.
Topics: Animals; Blotting, Western; Cell Line; CSK Tyrosine-Protein Kinase; Fibroblasts; Glutamic Acid; Hippocampus; Mice; Microscopy, Fluorescence; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Protein-Tyrosine Kinases; Reactive Oxygen Species; src-Family Kinases; Tyrosine | 2002 |
Extracellular glutamate in the brains of children with severe head injuries: a pilot microdialysis study.
Topics: Adolescent; Analysis of Variance; Brain; Child; Child, Preschool; Chromatography, High Pressure Liquid; Craniocerebral Trauma; Extracellular Space; Female; Glasgow Coma Scale; Glutamic Acid; Glutamine; Humans; Male; Microdialysis; Monitoring, Physiologic; Pilot Projects; Prognosis; Time Factors; Tomography, X-Ray Computed; Tyrosine | 2002 |
Study of second-site suppression in the pheP gene for the phenylalanine transporter of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Bacterial Proteins; Consensus Sequence; Escherichia coli; Escherichia coli Proteins; GABA Plasma Membrane Transport Proteins; Genes, Bacterial; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters; Phenylalanine; Proline; Tyrosine | 2002 |
The beta G156C substitution in the F1-ATPase from the thermophilic Bacillus PS3 affects catalytic site cooperativity by destabilizing the closed conformation of the catalytic site.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Bacillus; Binding Sites; Catalysis; Catalytic Domain; Cysteine; Dimethylamines; Enzyme Stability; Glutamic Acid; Glycine; Hydrolysis; Magnesium; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Sodium Azide; Tryptophan; Tyrosine; Valine | 2002 |
Influence of the protein environment on the properties of a tyrosyl radical in reaction centers from Rhodobacter sphaeroides.
Topics: Arginine; Dimerization; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Light-Harvesting Protein Complexes; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Spectrophotometry; Spectroscopy, Near-Infrared; Tyrosine | 2002 |
Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Kinetics; Mice; Peptides; Phosphorylation; Protein Subunits; Structure-Activity Relationship; Tyrosine | 2003 |
Charge-charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI=3.5) and a basic variant (pI=10.2).
Topics: Aspartic Acid; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Isoelectric Point; Isoenzymes; Lysine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Ribonucleases; Tyrosine | 2003 |
Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors.
Topics: Carbon-Carbon Double Bond Isomerases; Catalytic Domain; Crystallography; Cysteine; Epoxy Compounds; Escherichia coli; Glutamic Acid; Hemiterpenes; Kinetics; Organophosphorus Compounds; Protein Structure, Secondary; Tyrosine | 2003 |
[Analysis of amino acids in Trigonella foenumgraecum seeds].
Topics: Amino Acids; Aspartic Acid; Drugs, Chinese Herbal; Glutamic Acid; Glycine; Seeds; Trigonella; Tyrosine | 1998 |
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aspartic Acid; Binding Sites; Brain Chemistry; Cerebral Cortex; Copper; Female; Glutamic Acid; Humans; Iron; Metals, Heavy; Methionine; Microscopy; Oxidation-Reduction; Plaque, Amyloid; Protein Structure, Secondary; Spectrum Analysis, Raman; Tyrosine; Zinc | 2003 |
The interaction of a constitutively active arrestin with the arrestin-insensitive 5-HT(2A) receptor induces agonist-independent internalization.
Topics: Amino Acid Substitution; Arrestins; Cells, Cultured; Glutamic Acid; Humans; Hydrolysis; Neurons; Phosphoproteins; Phosphorylation; Protein Conformation; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Transfection; Tyrosine | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
Mutation of active site residues of the puromycin-sensitive aminopeptidase: conversion of the enzyme into a catalytically inactive binding protein.
Topics: Aminopeptidases; Binding Sites; Catalysis; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Dynorphins; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Glutamine; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Synthesis Inhibitors; Puromycin; Recombinant Proteins; Substrate Specificity; Time Factors; Tyrosine | 2003 |
Amino acids Glu323, Tyr324, Glu330, and Val331 of factor Va heavy chain are essential for expression of cofactor activity.
Topics: Amino Acids; Animals; Anisotropy; Binding Sites; Blotting, Western; COS Cells; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Factor Va; Factor Xa; Glutamic Acid; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Peptides; Protein Binding; Prothrombin; Recombinant Proteins; Spectrometry, Fluorescence; Thrombin; Thromboplastin; Time Factors; Transfection; Tyrosine; Valine | 2003 |
Pain intensity, illness duration, and protein catabolism in temporomandibular disorder patients with chronic muscle pain.
Topics: Adult; Amino Acids; Case-Control Studies; Chi-Square Distribution; Chronic Disease; Cohort Studies; Confidence Intervals; Facial Pain; Female; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Humans; Leucine; Male; Pain Measurement; Protein Denaturation; Succinic Acid; Temporomandibular Joint Disorders; Time Factors; Tyrosine | 2003 |
Coagulase-negative staphylococcal membrane-damaging toxins, pain intensity, and metabolic changes in temporomandibular disorder patients with chronic muscle pain.
Topics: Adult; Amino Acids; Bacterial Toxins; Case-Control Studies; Chronic Disease; Confidence Intervals; Facial Pain; Female; Glutamic Acid; Hemolysin Proteins; Humans; Leucine; Male; Nasal Mucosa; Odds Ratio; Pain Measurement; Staphylococcus; Staphylococcus aureus; Temporomandibular Joint Disorders; Tyrosine | 2003 |
Gamma irradiation of polypeptides: transformation of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Methionine; Peptides; Phenylalanine; Proline; Radiation Effects; Tyrosine | 1963 |
Nutrition of five Bacteroides strains.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Fusobacterium; Glucose; Glutamic Acid; Histidine; Lysine; Phenylalanine; Purines; Tyrosine; Vitamins | 1962 |
EFFECT OF TETRACYCLINES ON THE INTRACELLULAR AMINO ACIDS OF MOLDS.
Topics: Alanine; Amino Acids; Arginine; Fungi; Glutamic Acid; Lysine; Phenylalanine; Proline; Tetracycline; Tetracyclines; Tyrosine | 1963 |
EFFECT OF CATIONS UPON HYDROPHOBICITY OF YEASTS GROWN IN AMINO ACID MEDIA.
Topics: Amino Acids; Ammonium Compounds; Cations; Chlorides; Culture Media; Glutamic Acid; Histidine; Hydrophobic and Hydrophilic Interactions; Lysine; Nitrogen; Phenylalanine; Proline; Quaternary Ammonium Compounds; Research; Tryptophan; Tyrosine; Valine; Yeasts | 1963 |
ANTIGENICITY OF POLYPEPTIDES (POLY ALPHA AMINO ACIDS). XII. IMMUNOLOGICAL STUDIES WITH A NEW GROUP OF SYNTHETIC COPOLYMERS.
Topics: Alanine; Animals; Antibody Formation; Antigens; Glutamates; Glutamic Acid; Guinea Pigs; Immunoelectrophoresis; Lysine; Peptides; Polymers; Precipitin Tests; Rabbits; Research; Tyrosine; Valine | 1964 |
INHIBITION OF TRYPSIN BY COPOLYMERS OF GLUTAMIC ACID AND OTHER AMINO ACIDS.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Colorimetry; Glutamates; Glutamic Acid; Leucine; Peptides; Phenylalanine; Research; Trypsin; Trypsin Inhibitors; Tyrosine; Urea | 1964 |
CONFORMATIONAL DEPENDENCE OF THE FLUORESCENCE OF COPOLYMERS OF TYROSINE AND GLUTAMIC ACID IN AQUEOUS SOLUTION.
Topics: Chemical Phenomena; Chemistry, Physical; Fluorescence; Glutamates; Glutamic Acid; Molecular Conformation; Polymers; Solutions; Tyrosine | 1964 |
[CHANGES IN THE BLOOD SUGAR IN THE DOG AFTER INTRADUODENAL GLUCOSE INJECTION SUPPLEMENTED BY L-TYROSINE OR L + GLUTAMIC ACID].
Topics: Blood Glucose; Carbohydrate Metabolism; Dietary Supplements; Dogs; Duodenum; Glucose; Glutamates; Glutamic Acid; Injections; Intestinal Absorption; Pharmacology; Research; Tyrosine | 1964 |
OPTICAL ROTATORY DISPERSION STUDIES OF POLY-L-TYROSINE AND COPOLYMERS OF L-GLUTAMIC ACID AND L-TYROSINE. SIGNIFICANCE OF THE TYROSYL COTTON EFFECTS WITH RESPECT TO PROTEIN CONFORMATION.
Topics: Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Optical Rotatory Dispersion; Peptides; Polymers; Protein Conformation; Research; Spectrum Analysis; Tyrosine | 1964 |
AMINO ACID UTILIZATION BY ALCALIGENES VISCOLACTIS FOR GROWTH AND SLIME PRODUCTION.
Topics: Alcaligenes; Amino Acids; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Colorimetry; Culture Media; Glucose; Glutamic Acid; Glutamine; Lactose; Nitrogen; Proline; Research; Salts; Tyrosine | 1965 |
The N-terminal amino acids of human plasma proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Proteins; Glutamic Acid; Glycine; Humans; Leucine; Nuclear Receptor Subfamily 4, Group A, Member 2; Tyrosine; Valine | 1962 |
The role of FhuD2 in iron(III)-hydroxamate transport in Staphylococcus aureus. Demonstration that FhuD2 binds iron(III)-hydroxamates but with minimal conformational change and implication of mutations on transport.
Topics: Amino Acid Sequence; Biological Assay; Biological Transport; Carrier Proteins; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Ferric Compounds; Glutamic Acid; Hydroxamic Acids; Ligands; Maltose-Binding Proteins; Membrane Transport Proteins; Models, Biological; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Periplasmic Binding Proteins; Phenotype; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Scattering, Radiation; Spectrometry, Fluorescence; Staphylococcus aureus; Tyrosine; X-Rays | 2003 |
[LysB3, GluB29] insulin: a novel insulin analog with enhanced beta-cell protective action.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Fatty Acids; Glutamic Acid; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Lysine; Nucleosomes; Palmitic Acid; Phosphoproteins; Phosphorylation; Precipitin Tests; Rats; Tyrosine | 2003 |
Crystal structure of the E2 transactivation domain of human papillomavirus type 11 bound to a protein interaction inhibitor.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acids; Binding Sites; Calorimetry; Circular Dichroism; Crystallography, X-Ray; DNA Mutational Analysis; Dose-Response Relationship, Drug; Glutamic Acid; Histidine; Leucine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Transcriptional Activation; Tyrosine; Ultracentrifugation; Viral Proteins | 2004 |
Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules.
Topics: Animals; Carboxypeptidases; Catalase; COS Cells; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Microscopy, Fluorescence; Microtubules; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Phosphatase 1; Temperature; Tyrosine | 2003 |
Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Carrier Proteins; Catalysis; Circular Dichroism; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Glutathione Transferase; Histidine; Macrophages; Mitogen-Activated Protein Kinase Kinases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Rats; Rats, Inbred F344; Recombinant Proteins; Spectrophotometry; Time Factors; Tyrosine; Urea; Zinc | 2004 |
Beta-galactosidases (Escherichia coli) with double substitutions show that Tyr-503 acts independently of Glu-461 but cooperatively with Glu-537.
Topics: beta-Galactosidase; Binding Sites; Circular Dichroism; Enzyme Activation; Enzyme Stability; Escherichia coli; Galactose; Glutamic Acid; Glycerol; Hot Temperature; Methanol; Mutagenesis, Site-Directed; Tyrosine | 2003 |
Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation.
Topics: Acetyltransferases; Amino Acid Sequence; Amino Acid Substitution; Aminoglycosides; Anti-Bacterial Agents; Conserved Sequence; Drug Resistance, Bacterial; Enterococcus faecium; Enzyme Activation; Glutamic Acid; Histidine; Histone Acetyltransferases; Hydrogen-Ion Concentration; Kinetics; Leucine; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed; Tyrosine | 2004 |
Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase.
Topics: Aspartic Acid; Binding Sites; Catalytic Domain; Chitinases; Computational Biology; Computer Simulation; Conserved Sequence; DNA Mutational Analysis; Glutamic Acid; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Mutation; Serratia marcescens; Structure-Activity Relationship; Tyrosine | 2004 |
Site within N-Methyl-D-aspartate receptor pore modulates channel gating.
Topics: Asparagine; Calcium; Cells, Cultured; Glutamic Acid; Humans; Ion Channels; Mutagenesis, Site-Directed; Mutation; Protein Structure, Secondary; Receptors, N-Methyl-D-Aspartate; Transfection; Tyrosine | 2004 |
Gatekeeping layer effect: a poly(lactic acid)-coated mesoporous silica nanosphere-based fluorescence probe for detection of amino-containing neurotransmitters.
Topics: Acetals; Dopamine; Fluorescent Dyes; Glutamic Acid; Kinetics; Lactic Acid; Microscopy, Electron; Nanotechnology; Neurotransmitter Agents; Phthalic Acids; Polyesters; Polymers; Silicon Dioxide; Spectrometry, Fluorescence; Tyrosine | 2004 |
The aspartic acid, glutamic acid, proline and tyrosine content of meat.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Humans; Meat; Proline; Tyrosine | 1952 |
Resonance Raman spectroscopy reveals the origin of an intermediate wavelength form in photoactive yellow protein.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Deuterium Exchange Measurement; Glutamic Acid; Glutamine; Kinetics; Phenylalanine; Photoreceptors, Microbial; Quantum Theory; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thermodynamics; Thiocyanates; Threonine; Tyrosine; Valine | 2004 |
Adenylylation and catalytic properties of Mycobacterium tuberculosis glutamine synthetase expressed in Escherichia coli versus mycobacteria.
Topics: Ammonia; Catalysis; Escherichia coli; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hydrolysis; Mass Spectrometry; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Mycobacteriaceae; Mycobacterium tuberculosis; Nitrogen; Phosphoric Diester Hydrolases; Snake Venoms; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Time Factors; Tyrosine | 2004 |
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.
Topics: Cell Line; Down-Regulation; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Transferase; Humans; Mutation; Phenylalanine; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Inhibitors; Glutamic Acid; Homocysteine; Humans; Kinetics; Ligands; Methionine; Methyltransferases; Mutagenesis, Site-Directed; Protein Binding; Sarcosine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan; Tyrosine | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Heme structures of five variants of hemoglobin M probed by resonance Raman spectroscopy.
Topics: Carbon; Glutamic Acid; Heme; Hemoglobin M; Hemoglobins; Hemoglobins, Abnormal; Histidine; Ions; Models, Chemical; Mutation; Oxygen; Spectrum Analysis, Raman; Tyrosine | 2004 |
Tyrosine phosphorylation and regulation of the AMPA receptor by SRC family tyrosine kinases.
Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Endocytosis; Excitatory Amino Acid Agonists; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Mice; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Nuclear Proteins; Phosphorylation; Protein Subunits; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Tyrosine | 2004 |
Kinetic studies of Thermobifida fusca Cel9A active site mutant enzymes.
Topics: Actinomycetales; Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Carboxymethylcellulose Sodium; Cellulase; Enzyme Activation; Fibronectins; Glutamic Acid; Kinetics; Leucine; Lysine; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Substrate Specificity; Threonine; Tyrosine | 2004 |
Interaction of aluminium ions with some amino acids present in human blood.
Topics: Aluminum; Amino Acids; Aspartic Acid; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Copper; Filtration; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Ions; Ligands; Lysine; Metals; o-Phthalaldehyde; Ornithine; Spectrophotometry, Atomic; Tyrosine | 2004 |
Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
Topics: Asparagine; Bacillus cereus; Bacterial Proteins; beta-Amylase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Maltose; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Plant Proteins; Threonine; Tyrosine | 2004 |
Identification of residues within UvrB that are important for efficient DNA binding and damage processing.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Bacillus; Base Sequence; Binding Sites; Cholesterol; DNA; DNA Damage; DNA Helicases; DNA Repair; Escherichia coli Proteins; Glutamic Acid; Hydrolysis; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Tyrosine | 2004 |
The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, is temperature sensitive.
Topics: Acyl-CoA Dehydrogenase; Amino Acid Substitution; Animals; Circular Dichroism; Enzyme Stability; Escherichia coli; Fibroblasts; Glutamic Acid; Histidine; Humans; Infant, Newborn; Lymphocytes; Lysine; Mitochondria, Liver; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Neonatal Screening; Oxidation-Reduction; Rats; Recombinant Proteins; Structure-Activity Relationship; Tyrosine | 2004 |
Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II.
Topics: Amino Acid Sequence; beta-Lactamases; Cell Line; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Fluorescence Resonance Energy Transfer; GABA Plasma Membrane Transport Proteins; Genetic Complementation Test; Glutamic Acid; Humans; Hydrogen Bonding; Kinetics; Leucine; Light; Membrane Transport Proteins; Microscopy, Fluorescence; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sodium; Time Factors; Tyrosine | 2004 |
Factors controlling the complex architecture of native and modified cyclodextrins with dipeptide (Z-Glu-Tyr) studied by microcalorimetry and NMR spectroscopy: critical effects of peripheral bis-trimethylamination and cavity size.
Topics: Calorimetry; Carbohydrate Conformation; Carbohydrate Sequence; Cyclodextrins; Dipeptides; Glutamic Acid; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Conformation; Stereoisomerism; Thermodynamics; Tyrosine | 2004 |
Trapped tyrosyl radical populations in modified reaction centers from Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Darkness; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamic Acid; Light; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Tyrosine | 2004 |
Jak2 tyrosine kinase residues glutamic acid 1024 and arginine 1113 form a hydrogen bond interaction that is essential for Jak-STAT signal transduction.
Topics: Alanine; Algorithms; Amino Acid Sequence; Angiotensin II; Animals; Arginine; Blotting, Western; Cell Line; COS Cells; Crystallography, X-Ray; Cytoplasm; DNA-Binding Proteins; Gene Expression Regulation; Genes, Dominant; Glutamic Acid; Hydrogen Bonding; Immunoprecipitation; Janus Kinase 2; Luciferases; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; STAT1 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Transfection; Tyrosine | 2004 |
Oxygen reactions in p-hydroxybenzoate hydroxylase utilize the H-bond network during catalysis.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Amino Acid Substitution; Catalysis; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxylation; Lysine; Methionine; Oxidation-Reduction; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas fluorescens; Tyrosine | 2004 |
Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone.
Topics: Animals; Anti-Bacterial Agents; Body Temperature; Brain; Ceftriaxone; Cell Line, Tumor; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Clindamycin; Colony Count, Microbial; Glutamic Acid; Glycerol; Humans; Lactic Acid; Leukocyte Count; Lipid Peroxidation; Lipopolysaccharides; Male; Meningitis, Pneumococcal; Microdialysis; Neuroprotective Agents; Rabbits; Teichoic Acids; Tyrosine | 2004 |
Genetic variants of ApoE account for variability of plasma low-density lipoprotein and apolipoprotein B levels in FHBL.
Topics: Adult; Apolipoproteins B; Apolipoproteins E; Female; Frameshift Mutation; Gene Deletion; Genetic Variation; Genotype; Glutamic Acid; Guanine; Humans; Hypobetalipoproteinemias; Lipoproteins, LDL; Male; Pedigree; Phenotype; Point Mutation; Thymine; Tyrosine | 2005 |
Proton pathways in green fluorescence protein.
Topics: Animals; Aspartic Acid; Binding Sites; Biophysics; Crystallography, X-Ray; Cytoplasm; Databases, Protein; Glutamic Acid; Glutamine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Light; Lysine; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Point Mutation; Protein Conformation; Protons; Scyphozoa; Solvents; Spectrophotometry; Threonine; Time Factors; Tyrosine; Water; X-Rays | 2005 |
Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Azo Compounds; Binding Sites; Cations, Divalent; Chelating Agents; Cobalt; Copper; Crystallography, X-Ray; Enzyme Inhibitors; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenylalanine; Pyridones; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tyrosine | 2005 |
Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates.
Topics: Archaeal Proteins; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Fructose-Bisphosphate Aldolase; Glutamic Acid; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Schiff Bases; Structure-Activity Relationship; Substrate Specificity; Thermoproteus; Tyrosine | 2005 |
Dual-surface modification of the tobacco mosaic virus.
Topics: Capsid; Glutamic Acid; Models, Molecular; Tobacco Mosaic Virus; Tyrosine | 2005 |
Base catalysis of chromophore formation in Arg96 and Glu222 variants of green fluorescent protein.
Topics: Amino Acid Sequence; Anions; Arginine; Carbon; Catalysis; Glutamic Acid; Glycine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen; Peptides; Protein Binding; Protons; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Temperature; Time Factors; Trypsin; Tyrosine; Ultraviolet Rays | 2005 |
Kinetic analysis of the role of the tyrosine 13, phenylalanine 56 and glutamine 54 network in the U1A/U1 hairpin II interaction.
Topics: Amino Acid Sequence; Amino Acid Substitution; DNA Mutational Analysis; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Phenylalanine; Protein Binding; Ribonucleoprotein, U1 Small Nuclear; RNA-Binding Proteins; RNA, Small Nuclear; Tyrosine | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
Short communication: Amino acids antagonistic to the amino acids inhibitory for growth rate of mixed ruminal bacteria.
Topics: Amino Acids; Animals; Bacteria; Cattle; Diet; Feedback, Physiological; Female; Fermentation; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Threonine; Tryptophan; Tyrosine; Valine | 2005 |
Isolation, structure determination, synthesis, and sensory activity of N-phenylpropenoyl-L-amino acids from cocoa (Theobroma cacao).
Topics: Amides; Amino Acids; Aspartic Acid; Cacao; Chromatography, High Pressure Liquid; Cinnamates; Glutamic Acid; Humans; Isomerism; Molecular Structure; Seeds; Taste; Tyrosine | 2005 |
Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currents.
Topics: Amino Acid Sequence; Barium; Biological Transport; Calcium; Calcium Channels; Calcium Channels, L-Type; Cations; Cations, Divalent; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Ion Channel Gating; Ions; Kinetics; Lysine; Membrane Potentials; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Tyrosine | 2005 |
The excitoprotective effect of N-methyl-D-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Antibodies; Autocrine Communication; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Time Factors; Tyrosine | 2005 |
An intact phosphocholine binding site is necessary for transgenic rabbit C-reactive protein to protect mice against challenge with platelet-activating factor.
Topics: Animals; Binding Sites; C-Reactive Protein; Complement Activation; Dietary Carbohydrates; Dietary Proteins; Glutamic Acid; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylalanine; Phosphorylcholine; Platelet Activating Factor; Protein Binding; Rabbits; Survival Analysis; Tyrosine | 2005 |
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamic Acid; Humans; Hypersensitivity; Indomethacin; Inflammation; Kinetics; Ligands; Mice; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Tyrosine | 2005 |
Redox-induced protein structural changes in cytochrome bo revealed by Fourier transform infrared spectroscopy and [13C]Tyr labeling.
Topics: Animals; Biochemistry; Cattle; Copper; Cytochromes; Electron Transport Complex IV; Escherichia coli; Glutamic Acid; Histidine; Hydrogen; Hydrogen-Ion Concentration; Ligands; Light; Models, Chemical; Models, Molecular; Oxidation-Reduction; Oxygen; Potassium; Protein Conformation; Protein Structure, Secondary; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2005 |
Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Breast Neoplasms; Calorimetry; Cell Cycle Proteins; Crystallography, X-Ray; DNA Damage; DNA-Binding Proteins; Escherichia coli; Glutamic Acid; Glutamine; Glutathione Transferase; Histones; Humans; Models, Molecular; Models, Statistical; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphates; Phosphopeptides; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Trans-Activators; Tyrosine | 2005 |
Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?
Topics: Adenosine Diphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Databases, Protein; Evolution, Molecular; Glutamic Acid; Histidine; Humans; Models, Genetic; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Monte Carlo Method; Protein Conformation; Protein Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tryptophan; Tyrosine; Water | 2005 |
Determinants of substrate specificity in omega-aminotransferases.
Topics: Amino Acids; Aminobutyrates; Binding Sites; Biochemistry; Crystallography, X-Ray; Deuterium; DNA; Glutamic Acid; Humans; Isoleucine; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Protein Binding; Pyridoxal Phosphate; Recombinant Fusion Proteins; Spectrophotometry; Substrate Specificity; Time Factors; Transaminases; Tyrosine | 2005 |
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
Topics: Alanine; Animals; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ions; Kainic Acid; Kinetics; Ligands; Models, Biological; Models, Chemical; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; RNA, Complementary; Tryptophan; Tyrosine; Xenopus laevis | 2005 |
Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Aldehydes; Apoptosis; Cell Death; Cell Line, Tumor; Drug Resistance; Enzyme Inhibitors; Genetic Predisposition to Disease; Glutamic Acid; Guanine; Humans; Hydrogen Peroxide; Mutation; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Substantia Nigra; Tyrosine; Ubiquitin-Protein Ligases | 2005 |
Neuroprotective properties of the natural vitamin E alpha-tocotrienol.
Topics: Animals; Antioxidants; Arachidonate 12-Lipoxygenase; Brain; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Cerebral Cortex; CSK Tyrosine-Protein Kinase; Fluoresceins; Glutamic Acid; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuroprotective Agents; Organic Chemicals; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Random Allocation; Rats; Rats, Inbred SHR; src-Family Kinases; Stroke; Time Factors; Tocotrienols; Transfection; Tyrosine; Vitamin E | 2005 |
Invariant amino acids essential for decoding function of polypeptide release factor eRF1.
Topics: Amino Acid Sequence; Codon, Terminator; Glutamic Acid; Humans; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Termination Factors; Protein Denaturation; Tyrosine | 2005 |
Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Dipeptidases; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Protein Conformation; Tyrosine | 2005 |
A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking.
Topics: Alanine; Amino Acid Motifs; Animals; Biological Transport; Biotinylation; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cloning, Molecular; DNA, Complementary; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; Immunoprecipitation; Mutagenesis; Mutation; Phosphorylation; Platelet-Derived Growth Factor; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Sodium; Time Factors; Transfection; Tyrosine | 2006 |
Crystal structure at 1.45-A resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome.
Topics: Allergens; Amino Acid Sequence; Binding Sites; Catalysis; Catalytic Domain; Cross Reactions; Crystallography, X-Ray; Epitopes; Epitopes, B-Lymphocyte; Food Hypersensitivity; Fruit; Glucan Endo-1,3-beta-D-Glucosidase; Glucose; Glutamic Acid; Immunoglobulin E; Latex; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Musa; Phenylalanine; Polysaccharides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Proteins; Proteomics; Substrate Specificity; Syndrome; Time Factors; Triose-Phosphate Isomerase; Tyrosine | 2006 |
Chloride-dependency of amyloid beta protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Chlorides; Embryo, Mammalian; Glutamic Acid; Hippocampus; Intracellular Space; L-Lactate Dehydrogenase; Mitochondria; Neurons; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Wistar; Tyrosine | 2006 |
Residues Tyr253 and Glu255 in strand 3 of beta-sheet C of antithrombin are key determinants of an exosite made accessible by heparin activation to promote rapid inhibition of factors Xa and IXa.
Topics: Amino Acid Sequence; Antithrombin III; Binding Sites; Factor IXa; Factor Xa; Factor Xa Inhibitors; Glutamic Acid; Heparin; Humans; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Structure, Secondary; Thrombin; Tyrosine | 2006 |
Novel mutations in GJA8 associated with autosomal dominant congenital cataract and microcornea.
Topics: Adult; Arginine; Case-Control Studies; Cataract; Child; Congenital Abnormalities; Connexins; Cornea; Eye Proteins; Genes, Dominant; Glutamic Acid; Glutamine; Humans; India; Middle Aged; Mutation; Mutation, Missense; Myopia; Phenotype; Tyrosine | 2006 |
Kynurenic acid has a dual action on AMPA receptor responses.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Kynurenic Acid; Leucine; Male; Membrane Potentials; Mutagenesis; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Tyrosine; Xenopus laevis | 2006 |
Parity violating energetic difference and enantiomorphous crystalsp-caveats; reinvestigation of tyrosine crystallization.
Topics: Crystallization; Glutamic Acid; Stereoisomerism; Tyrosine | 2006 |
Trapping of the S2 to S3 state intermediate of the oxygen-evolving complex of photosystem II.
Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Glutamic Acid; Manganese; Methanol; Mutation; Oxidation-Reduction; Oxygen; Photosystem II Protein Complex; Spectroscopy, Near-Infrared; Spinacia oleracea; Temperature; Tyrosine | 2006 |
The planar conformation of a strained proline ring: a QM/MM study.
Topics: Alanine; Binding Sites; Computational Biology; Crystallography, X-Ray; Glutamic Acid; Models, Molecular; Molecular Structure; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics; Triose-Phosphate Isomerase; Tyrosine | 2006 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
Phosphorylation of ErbB4 on Tyr1056 is critical for inhibition of colony formation by prostate tumor cell lines.
Topics: Alternative Splicing; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Male; Phosphorylation; Prostatic Neoplasms; Receptor, ErbB-4; Signal Transduction; Tyrosine | 2006 |
Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Cell Line; Dimerization; GluK2 Kainate Receptor; Glutamic Acid; Humans; Hydrogen Bonding; Kainic Acid; Kidney; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Protein Binding; Protein Conformation; Protein Denaturation; Protein Interaction Mapping; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2006 |
Crystal structures of E. coli CcmG and its mutants reveal key roles of the N-terminal beta-sheet and the fingerprint region.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Protein Disulfide Reductase (Glutathione); Protein Folding; Sequence Alignment; Structure-Activity Relationship; Tyrosine | 2006 |
Characterization of the amino acids from Neisseria meningitidis MsrA involved in the chemical catalysis of the methionine sulfoxide reduction step.
Topics: Cysteine; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Methionine; Methionine Sulfoxide Reductases; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neisseria meningitidis; Oxidative Stress; Oxidoreductases; Sulfhydryl Compounds; Sulfoxides; Tyrosine | 2006 |
Structure-guided mutational analysis of T4 RNA ligase 1.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Binding Sites; Conserved Sequence; DNA Mutational Analysis; Glutamic Acid; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Conformation; RNA Ligase (ATP); Structure-Activity Relationship; Tyrosine; Viral Proteins | 2006 |
Posttranslational nitrotyrosination of alpha-tubulin induces cell cycle arrest and inhibits proliferation of vascular smooth muscle cells.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Cells, Cultured; Glutamic Acid; Microtubules; Muscle, Smooth, Vascular; Protein Processing, Post-Translational; Rats; Tubulin; Tyrosine | 2006 |
Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III.
Topics: Aspartic Acid; Binding Sites; Crystallization; Cytochromes b; Cytochromes c; DNA Mutational Analysis; Electron Transport Complex III; Enzyme Activation; Enzyme Stability; Glutamic Acid; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Saccharomyces cerevisiae; Tyrosine; Ubiquinone | 2007 |
Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Glutamic Acid; Humans; Interleukin-1 Receptor-Associated Kinases; Molecular Sequence Data; Phosphates; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein-Tyrosine Kinases; Tyrosine | 2006 |
The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.
Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Dizocilpine Maleate; Endothelial Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Proteins; Occludin; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Threonine; Tyrosine | 2007 |
Astrocytes aged in vitro show a decreased neuroprotective capacity.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Heme Oxygenase-1; Hydrogen Peroxide; Nerve Growth Factors; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Reactive Oxygen Species; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine | 2007 |
Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.
Topics: Alanine; Amino Acid Substitution; Arginine; Case-Control Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Histidine; Humans; Male; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Tyrosine | 2007 |
Detyrosinated microtubule protrusions in suspended mammary epithelial cells promote reattachment.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Line; Cell Surface Extensions; Epithelial Cells; Glutamic Acid; Humans; Mammary Glands, Animal; Mammary Glands, Human; Mice; Microtubules; Tubulin; Tyrosine | 2007 |
Electronic structure of the PYP chromophore in its native protein environment.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Glutamic Acid; Models, Molecular; Phenylalanine; Photoreceptors, Microbial; Threonine; Tyrosine; Valine | 2007 |
Caveolae nitration of Janus kinase-2 at the 1007Y-1008Y site: coordinating inflammatory response and metabolic hormone readjustment within the somatotropic axis.
Topics: Amino Acid Sequence; Animals; Antibodies; Antioxidants; Aspartic Acid; Binding Sites; Cattle; Caveolae; Epitopes; Glutamic Acid; Inflammation; Insulin-Like Growth Factor I; Janus Kinase 2; Lipopolysaccharides; Molecular Sequence Data; Nitrates; Nitric Oxide Synthase Type III; Phosphorylation; Rabbits; RNA, Messenger; Stress, Physiological; Suppressor of Cytokine Signaling Proteins; Tyrosine; Vitamin E | 2007 |
Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Dyrk Kinases; Escherichia coli; Gene Expression Regulation, Enzymologic; Glutamic Acid; Histidine; Humans; In Vitro Techniques; Kinetics; Mass Spectrometry; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Tyrosine | 2007 |
Regulation of c-Src activity in glutamate-induced neurodegeneration.
Topics: Animals; Caveolin 1; Cell Survival; Cells, Cultured; CSK Tyrosine-Protein Kinase; Glutamic Acid; Mice; Models, Biological; Neurodegenerative Diseases; Neurons; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; src-Family Kinases; Tyrosine | 2007 |
Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation.
Topics: Animals; Binding Sites; Cell Line, Tumor; Chemokine CCL11; Chemokines; Chemokines, CC; Down-Regulation; Eosinophils; Glutamic Acid; Mice; Models, Biological; Molecular Conformation; Receptors, CCR3; Receptors, Chemokine; Tyrosine; Up-Regulation; Xanthenes | 2007 |
An activated glutamate residue identified in photosystem II at the interface between the manganese-stabilizing subunit and the D2 polypeptide.
Topics: Binding Sites; Biological Evolution; Carboxylic Acids; Crystallography, X-Ray; Electrophoresis, Gel, Two-Dimensional; Glutamic Acid; Manganese; Mass Spectrometry; Molecular Conformation; Mutation; Oxygen; Photosynthesis; Photosystem II Protein Complex; Protein Processing, Post-Translational; Tyrosine | 2007 |
PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
Topics: Adenine; Amino Acid Motifs; Amino Acid Sequence; Arginine; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glutamic Acid; Holoenzymes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Tryptophan; Tyrosine | 2007 |
Characterization of Helicobacter pylori gamma-glutamyltranspeptidase reveals the molecular basis for substrate specificity and a critical role for the tyrosine 433-containing loop in catalysis.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; gamma-Glutamyltransferase; Glutamic Acid; Helicobacter pylori; Hydrolysis; Kinetics; Ligands; Models, Molecular; Protein Structure, Tertiary; Substrate Specificity; Tyrosine | 2007 |
A minor beta-structured conformation is the active state of a fusion peptide of vesicular stomatitis virus glycoprotein.
Topics: Amino Acid Sequence; Asparagine; Circular Dichroism; Glutamic Acid; Glycoproteins; Hydrogen-Ion Concentration; Liposomes; Micelles; Models, Chemical; Molecular Conformation; Molecular Sequence Data; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Tyrosine; Valine; Vesicular stomatitis Indiana virus | 2008 |
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Topics: Amino Acid Motifs; Asparagine; Biochemistry; Carbon-Carbon Lyases; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Fusarium; Glutamic Acid; Kinetics; Magnesium; Models, Chemical; Mutagenesis, Site-Directed; Serine; Tyrosine | 2008 |
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger.
Topics: Amino Acid Sequence; Antigens, Nuclear; Chromosomal Proteins, Non-Histone; Crystallography, X-Ray; DNA Mutational Analysis; Glutamic Acid; Histones; Humans; Kinetics; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Neoplasm Proteins; Nerve Tissue Proteins; Peptides; Protein Engineering; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; Repressor Proteins; Structure-Activity Relationship; Transcription Factors; Tumor Suppressor Proteins; Tyrosine | 2007 |
Comments in a discussion: differential rates of D- and L-tyrosine crystallization.
Topics: Crystallization; Glutamic Acid; Stereoisomerism; Tyrosine | 2008 |
The pyrroloquinoline quinone biosynthesis pathway revisited: a structural approach.
Topics: Bacterial Proteins; Computer Simulation; Crystallography, X-Ray; Glutamic Acid; Isomerism; Models, Molecular; PQQ Cofactor; Protease Inhibitors; Protein Conformation; Protein Processing, Post-Translational; Sequence Analysis; Structural Homology, Protein; Substrate Specificity; Tyrosine | 2008 |
EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia.
Topics: Animals; Binding, Competitive; Carrageenan; Ephrin-B2; Glutamic Acid; Hyperalgesia; Inflammation; Inflammation Mediators; Male; Neural Pathways; Neuronal Plasticity; Nociceptors; Pain, Intractable; Phosphorylation; Posterior Horn Cells; Rats; Rats, Wistar; Receptor, EphB1; Receptors, Eph Family; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Synaptic Transmission; Tyrosine | 2008 |
Increased tyrosine phosphorylation of PSD-95 by Src family kinases after brain ischaemia.
Topics: Animals; Binding Sites; Brain Ischemia; Cells, Cultured; Chlorocebus aethiops; COS Cells; Disks Large Homolog 4 Protein; Glutamic Acid; Hippocampus; Immunoblotting; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mutation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Tyrosine | 2009 |
Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices.
Topics: Animals; Bicuculline; Biophysical Phenomena; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; Immunoprecipitation; In Vitro Techniques; Male; Neuronal Plasticity; Neurons; Organometallic Compounds; Patch-Clamp Techniques; Phenanthrolines; Phosphorylation; Protein Subunits; Protein Transport; Protein Tyrosine Phosphatases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Synapses; Tyrosine | 2009 |
Interactions between human glutamate carboxypeptidase II and urea-based inhibitors: structural characterization.
Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Ions; Ligands; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Structure, Tertiary; Tyrosine; Urea; Zinc | 2008 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
Impaired mitochondrial respiration and protein nitration in the rat hippocampus after acute inhalation of combustion smoke.
Topics: Acute Disease; Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Hippocampus; Male; Mass Spectrometry; Mitochondria; Nerve Tissue Proteins; Nitrates; Oxygen Consumption; Proteomics; Rats; Rats, Sprague-Dawley; Smoke Inhalation Injury; Subcellular Fractions; Succinates; Tyrosine | 2009 |
Molecular modeling of ligand-receptor interactions in GABA C receptor.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Computer Simulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Phosphinic Acids; Protein Conformation; Pyridines; Receptors, GABA; Static Electricity; Tyrosine | 2009 |
Structural characterization of a human Fc fragment engineered for extended serum half-life.
Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Glutamic Acid; Half-Life; Histocompatibility Antigens Class I; Humans; Immunoglobulin Fc Fragments; Immunoglobulin G; Models, Molecular; Protein Conformation; Protein Engineering; Protein Stability; Rats; Receptors, Fc; Threonine; Tyrosine | 2009 |
Gas-phase IR spectroscopy of deprotonated amino acids.
Topics: Amino Acids; Anions; Aspartic Acid; Cysteine; Gases; Glutamic Acid; Phenylalanine; Protons; Serine; Spectrophotometry; Spectrophotometry, Infrared; Tyrosine | 2009 |
A conserved tyrosyl-glutamyl catalytic dyad in evolutionarily linked enzymes: carbapenam synthetase and beta-lactam synthetase.
Topics: Amidohydrolases; Amino Acid Sequence; Amino Acid Substitution; Aspartate-Ammonia Ligase; Carbon-Nitrogen Ligases; Catalysis; Conserved Sequence; Evolution, Molecular; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Pectobacterium carotovorum; Protons; Streptomyces; Tyrosine; Viscosity | 2009 |
Enhancing the fluorescence of tyr-59 in ubiquitin by blocking proton transfer.
Topics: Cells, Cultured; Fluorescence; Glutamic Acid; Hydrogen-Ion Concentration; Point Mutation; Protein Folding; Protons; Spectrophotometry; Temperature; Tyrosine; Ubiquitin | 2009 |
Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter.
Topics: Amino Acid Substitution; Cell Line; Cell Membrane; Cysteine; Dipeptides; Extracellular Space; Glutamic Acid; Glycine; Humans; Mutagenesis, Site-Directed; Peptide Transporter 1; Protein Structure, Tertiary; Protein Transport; Symporters; Tyrosine | 2009 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
[Fluorescence analysis of trace glucose using glucose oxidase and horseradish peroxidase].
Topics: Cystine; Fluorescence; Glucose; Glucose Oxidase; Glutamic Acid; Horseradish Peroxidase; Hydrogen Peroxide; Lysine; Oxidation-Reduction; Rhodamines; Spectrometry, Fluorescence; Tyrosine | 2009 |
Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperalgesia; Inflammation Mediators; Ketamine; Male; Nociceptors; Pain, Postoperative; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord; Synaptic Transmission; Tyrosine | 2009 |
Down-regulation of Na+-coupled glutamate transporter EAAT3 and EAAT4 by AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Arginine; Dose-Response Relationship, Drug; Down-Regulation; Endosomal Sorting Complexes Required for Transport; Excitatory Amino Acid Transporter 3; Excitatory Amino Acid Transporter 4; Glutamic Acid; Glutamine; Humans; Membrane Potentials; Microscopy, Confocal; Mutation; Nedd4 Ubiquitin Protein Ligases; Nitrogen Oxides; Oocytes; Patch-Clamp Techniques; Transduction, Genetic; Tyrosine; Ubiquitin-Protein Ligases; Xenopus | 2010 |
Avt5p is required for vacuolar uptake of amino acids in the fission yeast Schizosaccharomyces pombe.
Topics: Amino Acid Transport Systems; Amino Acids; Arginine; Biological Transport; Glutamic Acid; Histidine; Lysine; Membrane Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine; Vacuoles; Vesicular Transport Proteins | 2010 |
Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
Topics: Binding Sites; Blood Proteins; Calcium; Cell Membrane; Crystallography, X-Ray; Cysteine; Factor Xa; Glutamic Acid; Humans; Kinetics; Light; Models, Molecular; Mutation; Phospholipids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Scattering, Radiation; Serpins; Tyrosine | 2010 |
Requirements for catalysis in the Cre recombinase active site.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Biocatalysis; Catalytic Domain; Glutamic Acid; Histidine; Integrases; Lysine; Models, Molecular; Molecular Sequence Data; Recombination, Genetic; Tryptophan; Tyrosine; Vanadates | 2010 |
Differential expression of glu-tubulin in relation to mammary gland disease.
Topics: Adult; Aged; Aged, 80 and over; Breast Diseases; Breast Neoplasms; Female; Glutamic Acid; Humans; Middle Aged; Tubulin; Tyrosine | 2010 |
The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase.
Topics: Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Cyclization; Dipeptides; Esterification; Glutamic Acid; Models, Molecular; Mycobacterium tuberculosis; Peptide Synthases; Peptides, Cyclic; Protein Conformation; RNA, Transfer, Tyr; Serine; Tyrosine; Tyrosine-tRNA Ligase | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Glutamic Acid; Hippocampus; Mice; Nitrates; Nitro Compounds; Oxidative Stress; Proteins; Tyrosine | 2010 |
Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.
Topics: Animals; Calcium; Cocaine; Conditioning, Psychological; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Mice; Motor Activity; Neurons; Phenols; Phosphorylation; Piperidines; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Tyrosine | 2011 |
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways.
Topics: Analysis of Variance; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glutamic Acid; Hypoxia; Interleukin-10; Neurons; Neurotoxins; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-18; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tyrosine | 2011 |
H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis.
Topics: Amino Acid Sequence; Bacterial Proteins; Female; Gastric Mucosa; Genotype; Glutamic Acid; Helicobacter Infections; Helicobacter pylori; Host-Pathogen Interactions; Humans; Immunohistochemistry; Integrin alpha5beta1; Male; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Stomach; Stomach Neoplasms; Tyrosine | 2011 |
[Effect of dipeptide neurotensin analog dilept on extracellular concentrations of glutamate, GABA and HVA in N. accumbens of rat brain].
Topics: Animals; Antipsychotic Agents; Dipeptides; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Neurotensin; Nucleus Accumbens; Proline; Rats; Rats, Wistar; Tyrosine | 2010 |
Modulation of contact order effects in the two-state folding of stefins A and B.
Topics: Amino Acid Sequence; Cystatins; Glutamic Acid; Molecular Sequence Data; Peptides; Point Mutation; Polymorphism, Genetic; Protein Folding; Protein Stability; Protein Structure, Secondary; Thermodynamics; Tyrosine | 2011 |
A synthetic polypeptide electrospun biomaterial.
Topics: Biocompatible Materials; Cells, Cultured; Fibroblasts; Fluorescent Dyes; Glutamic Acid; Humans; Microscopy, Electron, Scanning; Peptides; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2011 |
Analysis of tubulin alpha-1A/1B C-terminal tail post-translational poly-glutamylation reveals novel modification sites.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Glutamic Acid; Mice; Mice, Inbred C57BL; Molecular Weight; Peptide Fragments; Peptide Mapping; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteolysis; Tandem Mass Spectrometry; Tubulin; Tyrosine | 2012 |
Specific residues of a conserved domain in the N terminus of the human cytomegalovirus pUL50 protein determine its intranuclear interaction with pUL53.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Blotting, Western; Cell Nucleus; Conserved Sequence; Cytomegalovirus; Glutamic Acid; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tyrosine; Viral Proteins | 2012 |
Structure and function of ∆1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa.
Topics: Animals; Berberine; Cannabis; Carbon Dioxide; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Intramolecular Oxidoreductases; Mutation; Protein Structure, Tertiary; Psychotropic Drugs; Structure-Activity Relationship; Tyrosine | 2012 |
Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1.
Topics: Actin Capping Proteins; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Depsipeptides; Formins; Genes, Dominant; Glutamic Acid; Integrins; Mice; Microtubule-Associated Proteins; Microtubules; NIH 3T3 Cells; rho GTP-Binding Proteins; Signal Transduction; Thiazolidines; Tyrosine | 2012 |
Conductance properties of the inwardly rectifying channel, Kir3.2: molecular and Brownian dynamics study.
Topics: Animals; Bee Venoms; Biophysics; Electric Conductivity; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Ion Channel Gating; Ions; Kinetics; Lysine; Magnesium; Mice; Models, Molecular; Models, Statistical; Molecular Conformation; Mutation; Peptides; Phenylalanine; Protein Binding; Tyrosine | 2013 |
Glutamate attenuates IGF-1 receptor tyrosine phosphorylation in mouse brain: possible significance in ischemic brain damage.
Topics: Animals; Brain; Brain Ischemia; Glutamic Acid; Humans; Insulin-Like Growth Factor I; Male; Mice; Phosphorylation; Receptor, IGF Type 1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tyrosine | 2012 |
Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blotting, Western; COS Cells; Flow Cytometry; Glutamic Acid; HEK293 Cells; Humans; Interleukin-2; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Lectins, C-Type; Lymphocyte Activation; Mutation; Oncogene Proteins, Fusion; Phenylalanine; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; T-Lymphocytes; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 2013 |
Glutamate acts as a partial inverse agonist to metabotropic glutamate receptor with a single amino acid mutation in the transmembrane domain.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Animals; Cattle; DNA Mutational Analysis; Fluorescence Resonance Energy Transfer; Glutamic Acid; Glycine; HEK293 Cells; Humans; Molecular Conformation; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenotype; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proteins; Receptors, Metabotropic Glutamate; Rhodopsin; Sequence Homology, Amino Acid; Tyrosine | 2013 |
Tyrosine phosphorylation regulates the endocytosis and surface expression of GluN3A-containing NMDA receptors.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Analysis of Variance; Animals; Biophysics; Biotinylation; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Clathrin; DNA-Binding Proteins; Electric Stimulation; Embryo, Mammalian; Endocytosis; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Mutagenesis; Mutation; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphorus Isotopes; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Binding; Protein Conformation; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Transfection; Transferrin; Tyrosine | 2013 |
Hydrogen bond strengths in phosphorylated and sulfated amino acid residues.
Topics: Amino Acids; Arginine; Computational Biology; Databases, Protein; Glutamic Acid; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Peptides; Phosphates; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Processing, Post-Translational; Proteins; Solvents; Static Electricity; Tyrosine | 2013 |
The role of the neuropeptide somatostatin on methamphetamine and glutamate-induced neurotoxicity in the striatum of mice.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Fluoresceins; Glutamic Acid; Male; Methamphetamine; Mice; Mice, Inbred ICR; Microinjections; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Octreotide; Somatostatin; Tyrosine; Tyrosine 3-Monooxygenase | 2013 |
Posttranslational nitration of tyrosine residues modulates glutamate transmission and contributes to N-methyl-D-aspartate-mediated thermal hyperalgesia.
Topics: Animals; Cytosol; Glutamic Acid; Glutamine; Hot Temperature; Hyperalgesia; Immunoprecipitation; Lumbar Vertebrae; Male; N-Methylaspartate; Nitrogen; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptosomes; Tyrosine | 2013 |
Glutamatergic dysbalance and oxidative stress in in vivo and in vitro models of psychosis based on chronic NMDA receptor antagonism.
Topics: Animals; Antipsychotic Agents; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Hippocampus; Male; Oxidative Stress; Rats; Rats, Long-Evans; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tyrosine | 2013 |
Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catalytic Domain; Collagen; Crystallography, X-Ray; Glutamic Acid; Humans; Matrix Metalloproteinase 13; Molecular Docking Simulation; Molecular Sequence Data; Mutation, Missense; Peptides; Protein Binding; Tyrosine | 2013 |
Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766.
Topics: Amino Acid Sequence; Base Pair Mismatch; Deoxyribonucleotides; DNA Polymerase I; Fluorescence Resonance Energy Transfer; Glutamic Acid; Kinetics; Protein Conformation; Tyrosine | 2013 |
Molecular determinants of common gating of a ClC chloride channel.
Topics: Action Potentials; Animals; Binding Sites; Chloride Channels; Chlorides; Evolution, Molecular; Gene Expression; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Models, Molecular; Patch-Clamp Techniques; Protein Binding; Protein Multimerization; Protein Subunits; Sequence Homology, Amino Acid; Torpedo; Tyrosine | 2013 |
Oxidative stress-associated neuroretinal dysfunction and nitrosative stress in diabetic retinopathy.
Topics: Adult; Case-Control Studies; Diabetic Retinopathy; Female; Glutamic Acid; Humans; Leukocytes, Mononuclear; Male; Malondialdehyde; Middle Aged; Nitrites; Oxidative Stress; Reactive Oxygen Species; Retina; Tyrosine; Vitreous Body | 2013 |
Effect of hyperglycemia on insulin receptor signaling in the cultured retinal Müller glial cells.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Hydrogen Peroxide; Hypoglycemic Agents; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Neuroglia; Oxidants; Phosphorylation; Protein Binding; Rats; Receptor, Insulin; Retina; Signal Transduction; Tyrosine | 2014 |
N-stearoyltyrosine protects against glutamate-induced oxidative toxicity by an apoptosis-inducing factor (AIF)-mediated caspase-independent cell death pathway.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis Inducing Factor; BH3 Interacting Domain Death Agonist Protein; Cell Death; Dose-Response Relationship, Drug; Glutamic Acid; Lipoxygenase; Mitochondria; Neuroprostanes; Neurotransmitter Agents; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Tyrosine; Up-Regulation | 2014 |
A "SYDE" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect.
Topics: Amino Acid Sequence; Aspartic Acid; Casein Kinase II; Consensus Sequence; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dictyostelium; Glutamic Acid; Humans; Molecular Sequence Data; Phosphorylation; Protein Interaction Domains and Motifs; Serine; Tyrosine | 2014 |
Generation of differentially modified microtubules using in vitro enzymatic approaches.
Topics: Acetylation; Acetyltransferases; Animals; Cell Line; Cloning, Molecular; Glutamic Acid; Humans; Microtubules; Models, Molecular; Peptide Synthases; Protein Processing, Post-Translational; Recombinant Proteins; Tubulin; Tyrosine | 2014 |
Regulation of microtubule motors by tubulin isotypes and post-translational modifications.
Topics: Amino Acid Sequence; Animals; Cricetinae; Dyneins; Glutamic Acid; Humans; Kinesins; Microtubule Proteins; Molecular Sequence Data; Protein Isoforms; Protein Processing, Post-Translational; Sequence Alignment; Tubulin; Tyrosine | 2014 |
Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.
Topics: Animals; Annexin A2; Calcium; Cell Line, Transformed; Extracellular Space; Fibrinolysin; Glutamic Acid; Green Fluorescent Proteins; Mice; Phosphorylation; Protein Transport; Proteolysis; Tyrosine | 2014 |
New force field parameters for metalloproteins I: Divalent copper ion centers including three histidine residues and an oxygen-ligated amino acid residue.
Topics: Aspartic Acid; Copper; Glutamic Acid; Histidine; Metalloproteins; Models, Molecular; Molecular Dynamics Simulation; Thermodynamics; Tyrosine | 2014 |
The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction.
Topics: Adipose Tissue; Aging; Animals; Arteries; Body Weight; Carnitine; Glutamic Acid; Malates; Male; Mice; Mitochondria; Neovascularization, Physiologic; Oxidative Stress; Oxygen Consumption; Succinic Acid; Triglycerides; Tyrosine; Vasodilation | 2014 |
A triple mutant in the Ω-loop of TEM-1 β-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis.
Topics: beta-Lactam Resistance; beta-Lactamases; Biocatalysis; Ceftazidime; Crystallography, X-Ray; Escherichia coli; Gene Expression; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutation; Penicillins; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2015 |
Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission.
Topics: alpha-Methyltyrosine; Animals; Dopamine; Fenclonine; Frontal Lobe; Glutamic Acid; Hippocampus; Male; Mice; Mice, Knockout; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Receptors, G-Protein-Coupled; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine; Zinc | 2015 |
[Determination of Trace Boron Based on Gold Nanorod Plasmonic Resonance Rayleigh Scattering Energy Transfer to the Coordinate].
Topics: Boric Acids; Boron; Buffers; Energy Transfer; Glutamic Acid; Gold; Hydrogen Peroxide; Nanotubes; Naphthalenesulfonates; Scattering, Radiation; Thiosemicarbazones; Trace Elements; Tyrosine; Vibration | 2015 |
Higher serum concentrations of tyrosine and glutamate in schizophrenia patients treated with clozapine, compared to in those treated with conventional antipsychotics.
Topics: Adult; Amino Acids; Antipsychotic Agents; Chromatography, Ion Exchange; Clopenthixol; Clozapine; Cohort Studies; Female; Glutamic Acid; Haloperidol; Humans; Insulin Resistance; Male; Middle Aged; Perphenazine; Prospective Studies; Psychotic Disorders; Schizophrenia; Thioridazine; Tyrosine | 2015 |
Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies.
Topics: Adult; Aged; Animals; Brain Neoplasms; Case-Control Studies; Cell Line, Tumor; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glioblastoma; Glutamic Acid; Heterografts; Humans; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Tomography, X-Ray Computed; Tyrosine | 2016 |
L-DOPA Reverses the Increased Free Amino Acids Tissue Levels Induced by Dopamine Depletion and Rises GABA and Tyrosine in the Striatum.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Forelimb; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Levodopa; Mice; Oxidopamine; Rotarod Performance Test; Taurine; Tyrosine | 2016 |
Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation.
Topics: Aging; Alzheimer Disease; Animals; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Hippocampus; Mice, Transgenic; Microelectrodes; Mitochondria; Neurotransmitter Agents; Nitric Oxide; Oxidative Phosphorylation; Oxygen Consumption; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tyrosine | 2016 |
Investigation of the protective effect of Paeonia lactiflora on Semen Strychni-induced neurotoxicity based on monitoring nine potential neurotoxicity biomarkers in rat serum and brain tissue.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dopamine; Drugs, Chinese Herbal; Glutamic Acid; Male; Nerve Growth Factor; Neuroprotective Agents; Paeonia; Plant Extracts; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 2017 |
Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.
Topics: Amino Acid Motifs; Amino Acid Substitution; Binding Sites; Crystallography, X-Ray; Gene Expression; Glutamic Acid; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Domains; Protein Folding; Protein Multimerization; Recombinant Proteins; Retinol-Binding Proteins, Cellular; Thermodynamics; Tyrosine | 2016 |
FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Line; Cytoplasm; Glutamic Acid; Inclusion Bodies; Kinesins; Mice; Microtubules; Mutation; NIH 3T3 Cells; Protein Transport; RNA; RNA-Binding Protein FUS; RNA-Binding Proteins; RNA, Messenger; Sarcoma; Tubulin; Tubulin Modulators; Tyrosine | 2017 |
Metabolic profiling of tyrosine, tryptophan, and glutamate in human urine using gas chromatography-tandem mass spectrometry combined with single SPE cleanup.
Topics: Biomarkers; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Humans; Limit of Detection; Metabolome; Metabolomics; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2017 |
A Tyrosine Residue Along with a Glutamic Acid of the Omega-Like Loop Governs the Beta-Lactamase Activity of MSMEG_4455 in Mycobacterium smegmatis.
Topics: Bacterial Proteins; beta-Lactamases; Glutamic Acid; Mycobacterium smegmatis; Protein Structure, Secondary; Tyrosine | 2017 |
Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.
Topics: Adult; Age Factors; Amino Acids; Biomarkers; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Tyrosine | 2018 |
Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling.
Topics: Acetylation; Animals; Cilia; Genes, Reporter; Glutamic Acid; Green Fluorescent Proteins; Hedgehog Proteins; Kinesins; Mice; Microtubule-Associated Proteins; NIH 3T3 Cells; Optical Imaging; Protein Processing, Post-Translational; Signal Transduction; Tubulin; Tyrosine | 2018 |
Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity.
Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Aspartic Acid; Chlorpyrifos; Cholinesterase Inhibitors; Cross-Linking Reagents; Crystallography, X-Ray; Glutamic Acid; Lysine; Models, Molecular; Neurotoxicity Syndromes; Peptides; Phosphorylation; Protein Aggregates; Swine; Tubulin; Tyrosine | 2018 |
The Role of Proton Transport in Gating Current in a Voltage Gated Ion Channel, as Shown by Quantum Calculations.
Topics: Arginine; Cell Membrane; Glutamic Acid; Ion Channel Gating; Ion Channels; Protons; Quantum Theory; Tyrosine | 2018 |
Environmental pH and a Glu364 to Gln mutation in the chlorophyll-binding CP47 protein affect redox-active TyrD and charge recombination in Photosystem II.
Topics: Amino Acid Substitution; Chlorophyll; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Light-Harvesting Protein Complexes; Models, Molecular; Oxidation-Reduction; Photosystem II Protein Complex; Protein Binding; Synechocystis; Tyrosine | 2019 |
Evidence for perturbed metabolic patterns in bipolar disorder subjects associated with lithium responsiveness.
Topics: Adult; Amino Acids, Branched-Chain; Bipolar Disorder; Dopamine; Female; Glutamic Acid; Homeostasis; Humans; Lithium Compounds; Male; Metabolome; Middle Aged; Phenylalanine; Psychotropic Drugs; Treatment Outcome; Tyrosine | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Carnosic Acid Pretreatment Attenuates Mitochondrial Dysfunction in SH-SY5Y Cells in an Experimental Model of Glutamate-Induced Excitotoxicity.
Topics: Abietanes; Apoptosis; Cell Line, Tumor; Cell Survival; Glutamic Acid; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Nitric Oxide; Oxidation-Reduction; Reactive Oxygen Species; Tyrosine | 2019 |
Neuroprotective effects of a protein tyrosine phosphatase inhibitor against hippocampal excitotoxic injury.
Topics: Animals; Brain; Cell Death; Cell Survival; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Temporal Lobe; Tyrosine; Vanadates | 2019 |
Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1.
Topics: Adenosine Triphosphatases; Glutamic Acid; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Models, Molecular; Molecular Chaperones; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Domains; Structure-Activity Relationship; Tyrosine | 2019 |
Quantification of the Dynamic Phosphorylation Process of ERK Using Stable Isotope Dilution Selective Reaction Monitoring Mass Spectrometry.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; HeLa Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Mutation; PC12 Cells; Phosphorylation; Rats; Signal Transduction; Threonine; Tyrosine | 2019 |
Birth weight related blood concentrations of the neurotransmission amino acids glutamine plus glutamate, phenylalanine and tyrosine in full-term breastfed infants perinatally.
Topics: Amino Acids; Birth Weight; Breast Feeding; Female; Glutamic Acid; Glutamine; Humans; Infant, Newborn; Male; Neurotransmitter Agents; Phenylalanine; Reference Values; Sex Characteristics; Tyrosine | 2020 |
Amino acids profiles of children who stutter compared to their fluent sibling.
Topics: Case-Control Studies; Child; Child, Preschool; Female; Glutamic Acid; Hair; Histidine; Humans; Isoleucine; Male; Siblings; Stuttering; Threonine; Tyrosine | 2020 |
Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase.
Topics: Coordination Complexes; Escherichia coli; Escherichia coli Proteins; Free Radicals; Glutamic Acid; Kinetics; Light; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protons; Rhenium; Ribonucleotide Reductases; Tyrosine | 2021 |
Role of Water in Proton-Coupled Electron Transfer between Tyrosine and Cysteine in Ribonucleotide Reductase.
Topics: Cysteine; Electron Transport; Electrons; Escherichia coli; Free Radicals; Glutamic Acid; Models, Molecular; Protons; Ribonucleotide Reductases; Tyrosine; Water | 2022 |
Bioconjugation Strategies for Tobacco Mild Green Mosaic Virus.
Topics: Aspartic Acid; Glutamic Acid; Nicotiana; Protein Subunits; RNA, Viral; Solvents; Tobacco Mosaic Virus; Tyrosine | 2022 |
A Glu-Glu-Tyr Sequence in the Cytoplasmic Tail of the M2 Protein Renders Influenza A Virus Susceptible to Restriction of the Hemagglutinin-M2 Association in Primary Human Macrophages.
Topics: Actins; Amino Acid Sequence; Glutamic Acid; Hemagglutinins; Host Microbial Interactions; Humans; Influenza A virus; Macrophages; Neuraminidase; Ribonucleoproteins; Tyrosine; Viral Matrix Proteins; Viroporin Proteins; Virus Assembly | 2022 |
[Mechanism of Cordyceps militaris against non-small cell lung cancer: based on serum metabolomics].
Topics: Alanine; Animals; Arginine; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cordyceps; Glutamic Acid; Glutamine; Glyoxylates; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Nitrogen; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 2022 |
Endogenous benzoic acid interferes with the signatures of amino acids and thiol compounds through perturbing N-methyltransferase, glutamate-cysteine ligase, and glutathione S-transferase activity in dairy products.
Topics: Amino Acids; Animals; Benzoic Acid; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glutathione Transferase; Goats; Histidine; Methyltransferases; Milk; Phenylalanine; Sulfhydryl Compounds; Tyrosine | 2022 |
Effects of three glutenins extracted in acidic, neutral and alkaline urea solutions on the retrogradation of wheat amylose and amylopectin.
Topics: Amylopectin; Amylose; Glutamic Acid; Proline; Spectroscopy, Fourier Transform Infrared; Starch; Triticum; Tyrosine | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Alterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto's thyroiditis.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Glutamic Acid; Glycine; Hashimoto Disease; Humans; Lysine; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tyrosine | 2023 |