tyrosine has been researched along with genistein in 372 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.27) | 18.7374 |
| 1990's | 247 (66.40) | 18.2507 |
| 2000's | 104 (27.96) | 29.6817 |
| 2010's | 20 (5.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bixby, JL; Jhabvala, P | 1 |
| Jung, G; Lieberknecht, A; Metzger, JW; Offermanns, S; Schmidt, U; Schultz, G; Seifert, R | 1 |
| Brown, TJ; Kallestad, JC; Ledbetter, JA; Linsley, PS; Schieven, GL | 1 |
| Leader, NK; Roberts, MH; Towles, JA | 1 |
| Andersson, LC; Heiskala, M; Mustelin, T; Ståhls, A | 1 |
| Benhamou, M; Gutkind, JS; Robbins, KC; Siraganian, RP; Stephan, V | 1 |
| Benhamou, M; Robbins, KC; Siraganian, RP; Stephan, V | 1 |
| Coggeshall, KM; Fukamachi, H; Inagaki, N; Ishizaka, K; Ishizaka, T; Kawakami, T; Takei, M | 1 |
| Broxmeyer, HE; Hendrie, PC; Kim, YJ; Kwon, BS; Mantel, C; Miyazawa, K; Yang, YC | 1 |
| Akimaru, K; Inoue, M; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T | 1 |
| Colamonici, OR; Platanias, LC | 1 |
| Donnenberg, MS; Finlay, BB; Kaper, JB; Rosenshine, I | 1 |
| Offermanns, S; Schultz, G | 1 |
| Davidai, G; Hazum, E; Lee, A; Schvartz, I | 1 |
| Altschuler, D; Lapetina, EG; Marti, KB; Torti, M; Yamamoto, K | 1 |
| Dotto, GP; Filvaroff, E; Stern, DF | 1 |
| Dhar, A; Paul, AK; Shukla, SD | 1 |
| Clark, EA; Deans, J; Draves, K; Lane, PJ; Ledbetter, JA; McConnell, FM; Schieven, GL | 1 |
| Nakajima, K; Wall, R | 1 |
| Daibata, M; Humphreys, RE; Mellinghoff, I; Sairenji, T; Takagi, S | 1 |
| Daibata, M; Humphreys, RE; Last, TJ; Parker, DC; Sairenji, T; Takagi, S | 1 |
| Druker, B; Griffin, JD; Ikeda, H; Ishikawa, J; Kanakura, Y; Kanayama, Y; Kitayama, H; Kuriu, A; Nishiura, T; Yagura, H | 1 |
| Igarashi, M; Komiya, Y | 1 |
| Bonjour, JP; Caverzasio, J | 1 |
| Eckert, D; Mufson, RA; Szabo, J | 1 |
| Green, SH; Qiu, MS | 1 |
| Edgecombe, M; Patel, R; Whitaker, M | 1 |
| Koike, T; Nakashima, S; Nozawa, Y | 1 |
| Altman, A; Coggeshall, KM; Isakov, N; Mustelin, T | 1 |
| Constantinou, A; Huberman, E; Kiguchi, K | 1 |
| Ohmura, Y; Teraoka, H; Tsukada, K | 1 |
| Giasson, E; Haddad, P; Leduc, I; Meloche, S | 1 |
| Forrest, JN; Lehrich, RW | 1 |
| Kobayashi, K; Nagasawa, S; Takahashi, K | 1 |
| Klebanoff, SJ; Ledbetter, JA; Liles, WC; Waltersdorph, AW | 1 |
| Baenziger, NL; Dalemar, LR; Jong, YJ; Wilhelm, B | 1 |
| Beauchemin, C; Chamberland, C; Marceau, N; Potworowski, EF | 1 |
| Keast, JR; Manley, SW; Yap, AS | 1 |
| Kanaide, H; Kobayashi, S; Nishimura, J | 1 |
| Goodwyn, D; Itaya, T; Kawamura, K; Miyagishima, T; Miyazaki, T; Okabe, M; Sakurada, K; Shoji, M; Uehara, M; Vogler, WR | 1 |
| Duan, RD; Wagner, AC; Williams, JA; Yule, DI | 1 |
| Anel, A; Kleinfeld, AM; Richieri, GV | 1 |
| Danaher, M; Fallon, RJ; Saxena, A; Saylors, RL | 1 |
| Hagmann, W | 1 |
| Biegelmann, E; Gerisch, G; Humbel, B; Jungbluth, A; Schweiger, A; von Arnim, V | 1 |
| Faris, M; Fu, SM; Gaskin, F; Parsons, JT | 1 |
| Della Bianca, V; Donini, M; Dusi, S; Gandini, G; Rossi, F | 1 |
| Hall, A; Ridley, AJ | 1 |
| Della Bianca, V; Donini, M; Dusi, S; Rossi, F | 1 |
| Hall, CL; Lange, LA; Turley, EA; Wang, C | 1 |
| Ito, T; Jagus, R; May, WS | 1 |
| de Juan, E; Koroma, BM | 1 |
| Finlay, BB; Foubister, V; Rosenshine, I; Ruschkowski, S | 1 |
| Eguchi, K; Kawabe, Y; Migita, K; Mizokami, A; Nagataki, S; Tsukada, T | 1 |
| Herberman, RB; Lin, WC; Rabinowich, H; Whiteside, TL | 1 |
| Abboud, HE; Biswas, P; Choudhury, GG; Grandaliano, G | 1 |
| Huang, TS; Kuo, ML; Lin, JK; Yang, NC | 1 |
| Jones, PM; Persaud, SJ | 1 |
| Bayna, EM; Cheresh, DA; Klemke, RL; Yebra, M | 1 |
| Blaser, K; Green, DR; Simon, HU; Yousefi, S | 1 |
| Carter, V; Gale, M; Parsons, M | 1 |
| Bissell, MJ; Desprez, PY; Roskelley, CD | 1 |
| Chess, PR; Finkelstein, JN; Ryan, RM | 1 |
| Ali, JY; Smalheiser, NR | 1 |
| Carpenter, G; McCollum, GW; Polk, DB | 1 |
| Devenish, RJ; Grubb, D; Hatzinisiriou, I; Linnane, AW; Payne, MJ; Ralph, SJ; Wines, BD | 1 |
| Huang, CK; Liang, L | 1 |
| Chang, NS | 1 |
| Brindle, NP; Hallett, MB; Lloyds, D | 1 |
| Corvaia, N; Coutant, KD; Ryder, NS | 1 |
| Soltoff, SP; Toker, A | 1 |
| Kumar, R; Shrivastava, A; Sodhi, A | 1 |
| Cuveele, JF; de Witte, PA; Merlevede, WJ; Vandenheede, JR | 1 |
| Brugge, JS; Foster, D; Mukhopadhyay, D; Sukhatme, VP; Tsiokas, L; Zhou, XM | 1 |
| Bolen, JB; Haskill, S; Juliano, RL; Lin, TH; Mondal, K; Rosales, C | 1 |
| Gawdi, G; Misra, UK; Pizzo, SV | 1 |
| Bittorf, T; Busfield, SJ; Callus, B; Cull, VS; Klinken, SP; Tilbrook, PA | 1 |
| Cheung, PY; Dackiw, AP; Fingerote, R; Levy, GA; Nathens, AB; Rotstein, OD; Zakrzewski, K | 1 |
| Di Salvo, J; Semenchuk, LA | 1 |
| Chong, AS; Xu, X | 1 |
| DuMaine, J; Morrison, AR; Rzymkiewicz, DM | 1 |
| Heruth, DP; Leyva, A; Rothberg, PG; Wetmore, LA | 1 |
| Chang, P; Greenberg, S; Silverstein, SC | 1 |
| Koide, Y; Ryu, K; Yamashita, Y; Yoshida, TO | 1 |
| Hall, FL; O'Neill, K; Torres, M | 1 |
| Amino, N; Nishiyama, S; Tada, H; Takada, K; Takano, T | 1 |
| Kumada, T; Miyata, H; Nozawa, Y | 1 |
| Colasanto, JM; Gomez-Cambronero, J; Huang, CK; Sha'afi, RI | 1 |
| Buchholz, MJ; Kim, YH; Nordin, AA | 1 |
| Autieri, MV; Coffman, FD; Cohen, S; Fresa, KL; Georgoff, I | 1 |
| Lee, KM; Toscas, K; Villereal, ML | 1 |
| Edashige, K; Sato, EF; Takehara, Y; Utsumi, K; Watanabe, Y | 1 |
| Lee, GM; Maness, PF; Miller, DR | 1 |
| Mendoza, C; Moos, J; Tesarik, J | 1 |
| Hirai, K; Koike, T; Morita, Y; Nozawa, Y | 1 |
| Bongrand, P; Bouhamdan, M; Capo, C; Huang, CK; Mege, JL; Sanguedolce, MV | 1 |
| Di Salvo, J; Lauer, J; Semenchuk, LA | 1 |
| Farndale, RW; Sage, SO; Sargeant, P | 2 |
| Kitamura, N; Komada, M | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| de Jonge, HR; Edixhoven, MJ; Tertoolen, LG; Tilly, BC; van den Berghe, N | 1 |
| Goldberg, DJ; Wu, DY | 1 |
| Breu, J; Petryniak, MA; Slack, BE; Srivastava, K; Wurtman, RJ | 1 |
| Baldi, E; Bonaccorsi, L; Forti, G; Luconi, M | 1 |
| Baldi, E; Bonaccorsi, L; Forti, G; Gervasi, G; Krausz, C; Luconi, M | 1 |
| Yang, SD; Yu, JS | 1 |
| de Quintana, KL; Negrescu, EV; Siess, W | 1 |
| Hashimoto, N; Iwashita, S; Ogashiwa, M | 1 |
| Gouilleux, F; Groner, B; Mundt, M; Wakao, H | 1 |
| Nibbering, PH; van Furth, R; Zheng, L; Zomerdijk, TP | 1 |
| Hajjar, JJ; Oliver, BL; Sha'afi, RI | 1 |
| Donini, M; Dusi, S; Rossi, F | 1 |
| Berg, M; Offermanns, S; Schultz, G; Seifert, R | 1 |
| Finlay, BB; Rosenshine, I; Tang, P | 1 |
| Enomoto, T; Okamoto, T; Sato, JD | 1 |
| Haskill, S; Juliano, RL; Kornberg, L; Lin, TH; Morris, J; Walker, JJ; Yurochko, A | 1 |
| Scott, RE; Wang, H | 1 |
| Shapiro, SZ; Wheeler-Alm, E | 1 |
| Cohen, ME; Donowitz, M; Montgomery, JL; Walker, MS | 1 |
| Faller, DV; Forman, LW; Mundschau, LJ; Weng, H | 1 |
| Azuma, EK; Kitagawa, S; Mizoguchi, H; Saito, M; Takaku, F; Umezawa, K; Yuo, A | 1 |
| Bergamaschi, G; Cazzola, M; Danova, M; Lucotti, C; Ponchio, L; Rosti, V | 1 |
| Granger, HJ; Hawker, JR | 1 |
| Dearden-Badet, MT; Revillard, JP | 1 |
| Kindy, MS | 1 |
| Czajkowski, A; Liu, J; Murty, VL; Piotrowski, J; Slomiany, A; Slomiany, BL | 1 |
| Sato, M; Yoshida, H; Yura, Y | 1 |
| Bankhurst, AD; Doshi, RN; Homma, Y; Whalen, MM | 1 |
| Honma, Y; Hozumi, M; Kanatani, Y; Kasukabe, T; Motoyoshi, K; Nagata, N | 1 |
| Bauer, J; Glaser, KB; Sung, A; Weichman, BM | 1 |
| David, M; Dixon, JE; Larner, AC; Romero, G; Zhang, ZY | 1 |
| Barnes, S; Peterson, G | 1 |
| Burns, DM; Kawase, T; Ogata, S; Orikasa, M | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 1 |
| Boarder, MR; Morton, C; Wilkie, N | 1 |
| Ichida, T; Tajima, Y; Takuma, T | 1 |
| Di Salvo, J; Kaplan, N | 1 |
| May, MJ; Morgan, AJ; Pearson, JD; Wheeler-Jones, CP | 1 |
| Castell, JV; Fabra, R; Gómez-Lechón, MJ; Guillén, I; Nakamura, T; Ponsoda, X; Trullenque, R | 1 |
| Koga, Y; Kubo, C; Nomoto, K; Okumura, Y; Sudo, N; Tanaka, K | 1 |
| Braverman, LE; Devito, WJ; Mori, K; Stone, S | 1 |
| Tseng, CP; Verma, AK | 1 |
| Adunyah, SE; Rivero, JA | 1 |
| Cavallini, D; Duprè, S; Fontana, M; Kodama, H; Sagara, Y; Zhang, J | 1 |
| Harbon, S; Leiber, D; Palmier, B | 1 |
| Krasil'nikov, MA; Mizenina, OA; Shatskaia, VA; Tatosian, AG | 1 |
| O'Regan, MH; Phillis, JW; Song, D | 1 |
| Davis-Amaral, EM; Goldstein, L; Musch, MW | 1 |
| Egashira, K; Imada, C; Kishimoto, T; Nakaike, R; Owada, MK; Shimokawa, H; Shiraishi, T; Takeshita, A; Tokunaga, O; Yasutake, H | 1 |
| Cossins, AR; Weaver, YR | 1 |
| Davis, MJ; Sharma, NR | 1 |
| Catling, AD; Cox, ME; Ely, CM; Parsons, SJ; Weber, MJ | 1 |
| Geibel, J; Sumpio, BE; Yano, Y | 1 |
| Auberger, P; Baeuerle, PA; Farahifar, D; Imbert, V; Livolsi, A; Mueller-Dieckmann, C; Pahl, HL; Peyron, JF; Rossi, B; Rupec, RA; Traenckner, EB | 1 |
| Agrawal, DK; Chisholm, LJ; Edwards, JD; Pearson, TJ | 1 |
| Jänne, OA; Palvimo, JJ; Reinikainen, P | 1 |
| Buckley, AR; Buckley, DJ; Rao, YP | 1 |
| Genco, RJ; Saito, A; Sojar, HT | 1 |
| Hamaguchi, M; Hayakawa, T; Iwata, H; Koike, T; Noguchi, T; Shinagawa, A; Suzuki, M; Yamashita, K | 1 |
| Han, JD; Rubin, CS | 1 |
| Madianos, PN; Papapanou, PN; Sandros, J | 1 |
| Becker, E; Bershadsky, A; Chausovsky, A; Geiger, B; Lyubimova, A | 1 |
| Gunst, SJ; Pavalko, FM; Wang, Z | 1 |
| Cirone, M; Faggioni, A; Frati, L; Tarasi, D; Zompetta, C | 1 |
| Ashour, MS; Fouda, SI; Molski, TF; Sha'afi, RI | 1 |
| Hargrove, ME; Ting, CC; Wang, J | 1 |
| Cesaro, L; Dalla Via, L; Deana, R; Scapin, M; Stimamiglio, M | 1 |
| Atkinson, TP; Yang, Q | 1 |
| Petryniak, MA; Slack, BE; Wurtman, RJ | 1 |
| Colamonici, OR; Krolewski, JJ; Platanias, LC; Sweet, M; Uddin, S | 1 |
| Murai, A; Nakahata, N; Nakamura, H; Ohizumi, Y; Rho, MC | 2 |
| Llinás, R; Mohammadi, M; Moreno, H; Schlessinger, J; Sugimori, M | 1 |
| Ganapathy, V; Kekuda, R; Leibach, FH; Torres-Zamorano, V | 1 |
| Inatome, R; Wang, X; Yamamura, H; Yanagi, S; Yang, C | 1 |
| Bitar, R; Dackiw, AP; Davreux, CJ; Lu, Z; McGilvray, ID; Rotstein, OD | 1 |
| Ganapathy, V; Kekuda, R; Leibach, FH; Prasad, PD; Torres-Zamorano, V | 1 |
| de Juan, E; Hayashi, A; Kim, HC; Weinberger, AW | 1 |
| Ganapathy, V; Kekuda, R; Leibach, FH | 1 |
| Rikihisa, Y; Zhang, Y | 1 |
| Jenab, S; Morris, PL | 1 |
| Nagel, G; Riordan, JR; Weinreich, F; Wood, PG | 1 |
| Goyal, RK; Hirano, I; Kakkar, R; Saha, JK; Szymanski, PT | 1 |
| Abu Kwaik, Y; Bondada, S; Haack, BJ; Venkataraman, C | 1 |
| Chien, T; Di Salvo, J; Nelson, SR | 1 |
| Bowden, ET; Mueller, SC; Sato, H; Seiki, M; Sitlani, J; Thompson, EW; Yu, M | 1 |
| Ido, M; Ito, Y; Kawano, M; Komada, H; Nishio, M; Ohgimoto, S; Okamoto, K; Sakurai, M; Suga, S; Tabata, N; Tsurudome, M; Watanabe, N | 1 |
| Arakawa, T; Fujiwara, Y; Fukuda, T; Higuchi, K; Kawada, N; Kobayashi, K; Komurasaki, T; Sasaki, E | 1 |
| Buerger, W; Freyer, D; Goebel, UB; Kirschning, CJ; Lamping, N; Pfeil, D; Schumann, RR; Weber, JR | 1 |
| Kuan, CY; Lee, SC; Wen, ZD; Yang, SD | 1 |
| Kaufmann, WK | 1 |
| Dugué, B; Ekokoski, E; Törnquist, K | 1 |
| Hinshaw, DB; Nguyen, PK; Omann, GM; Sweeney, JF | 1 |
| Love, DC; Mentink Kane, M; Mosser, DM | 1 |
| DeWild, LJ; Klein, JM; McCarthy, TA | 1 |
| Basson, MD; Emenaker, NJ; Rashid, Z | 1 |
| Lei, W; Levitt, ML; Mayotte, JE | 1 |
| Bae, MA; Kang, HS; Kim, YH; Rue, SW; Seu, JH | 1 |
| Carlini, CR; Francischetti, IM; Ghazaleh, FA; Guimarães, JA; Reis, RA | 1 |
| Hsu, CP; Mai, XY; Sheu, JC; Yang, CC; Yang, SD | 1 |
| de Boland, AR; Norman, AW | 1 |
| Dorta, ML; Favoreto, S; Yoshida, N | 1 |
| Gotoh, Y; Nagayama, M; Nakanishi, H; Yamanouchi, K | 1 |
| Duprè, S; Fontana, M; Hashimoto, K; Kodama, H; Sagara, Y; Sugahara, K; Zhang, J | 1 |
| Cardone, MH; Luton, F; Mostov, KE; Zhang, M | 1 |
| Hao, Q; Inagami, T; Kerins, DM; Tang, H; Vaughan, DE | 1 |
| Davis, FB; Davis, PJ; Gordinier, JK; Lin, HY; Martino, LJ; Wilcox, BD | 1 |
| Attali, B; Peretz, A; Sobko, A | 1 |
| DeVries, ME; Feldman, RD; Kelvin, DJ; Khandaker, MH; Mitchell, G; Pickering, JG; Rahimpour, R; Singhal, SK; Xu, L | 1 |
| Han, R; Yan, C | 2 |
| Eichel-Streiber, CV; Jakobs, KH; Olesch, S; Ott, S; Rümenapp, U; Schmidt, M | 1 |
| Garcia, LJ; Jensen, RT; Rosado, JA; Salido, GM | 1 |
| Kato, M; Kita, H; Morikawa, A; Tokuyama, K | 1 |
| Exton, JH; Kim, EG; Min, DS | 1 |
| Clunn, GF; Hughes, AD; Lymn, JS; Xie, L | 1 |
| Andrews, PA; Marverti, G | 1 |
| Bradford, MD; Soltoff, SP | 1 |
| Döring, F; Karschin, A; Wischmeyer, E | 1 |
| Gille, J; Kaufmann, R; Khalik, M; König, V | 1 |
| Ott, VL; Rapraeger, AC | 1 |
| Fernandis, AZ; Subrahmanyam, G | 1 |
| Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Moriishi, K; Oguma, K; Sasaki, M; Tomita, F | 1 |
| Hunzicker-Dunn, M; Lamm, ML; Rajagopalan-Gupta, RM | 1 |
| Garcia, JG; Gilbert-McClain, LI; Irwin, RP; Natarajan, V; Patterson, CE; Schaphorst, KL; Shi, S; Verin, AD | 1 |
| Haller, H; Kerren, T; Kettritz, R; Klein, JB; Luft, FC; Quass, P; Xu, YX | 1 |
| Kodama, H; Sagara, Y; Spirito, A; Sugahara, K; Zhang, J; Zhang, M | 1 |
| Cavalieri, E; Colasanti, M; Fabrizi, C; Lauro, GM; Mariotto, S; Menegazzi, M; Persichini, T; Suzuki, H | 1 |
| Burns, DM; Kawase, T; Oguro, A; Orikasa, M | 1 |
| Kwiatkowska, K; Sobota, A | 1 |
| Aoto, M; Fukami, Y; Horiuchi, Y; Iwasaki, T; Sato, K; Takeba, S; Tokmakov, AA | 1 |
| Nigam, SK; Tsukamoto, T | 1 |
| McDonald, TF; Ogura, T; Shuba, LM | 1 |
| Aoki, J; Hasegawa, H; Ichikawa, A; Katoh, H; Nakamura, K; Negishi, M; Yamaguchi, Y; Yasui, H | 1 |
| Feldman, RD; Kelvin, DJ; Khandaker, MH; Lazarovits, AI; Madrenas, J; Mitchell, GB; Pickering, JG; Pomerantz, DK; Rahimpour, R; Suria, H; Xu, L | 1 |
| Clayton, D; Padmanabhan, J; Shelanski, ML | 1 |
| Bedoya, FJ; Camacho, MJ; Carballo, M; Conde, J; Conde, M; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Sobrino, F | 1 |
| Haier, J; Nasralla, M; Nicolson, GL | 1 |
| Akhand, AA; Kato, M; Kurokawa, K; Liu, W; Miyata, T; Nakashima, I; Uchida, K; Yokoyama, I | 1 |
| Kimura, K; Kishino, M; Mune, M; Nishide, I; Sonobe, M; Tone, Y; Yamada, Y; Yukawa, S | 1 |
| Dachary-Prigent, J; Fressinaud, E; Freyssinet, JM; Martin, S; Martínez, MC; Meyer, D; Toti, F | 1 |
| Ford, CM; Li, S; Pickering, JG | 1 |
| Béguin, P; Carranza, ML; Caverzasio, J; Favre, H; Féraille, E; Geering, K; Gonin, S; Martin, PY; Pedemonte, C; Rousselot, M | 1 |
| Butz, S; Kemler, R; Ohsugi, M | 1 |
| Malbon, CC; Wang, Hy | 1 |
| Davis, FB; Davis, PJ; Lin, HY; Tsan, MF; White, JE | 1 |
| Becker, S; Mondal, K; Stephen Haskill, J | 1 |
| Hershman, KM; Levitan, ES | 1 |
| Hill, MA; Murphy, TV; Spurrell, BE | 1 |
| Strayer, DS; White, MK | 1 |
| Deleuze, C; Duvoid, A; Hussy, N; Moos, FC | 1 |
| Ha-Lee, YM; Kim, YK; Lee, Y; Sohn, J | 1 |
| Fujimoto, J; Furuyama, J; Hashimoto-Tamaoki, T; Itoh, T; Kishimoto, K; Nakanishi, K; Okamoto, E; Sasaki, Y; Ueki, T | 1 |
| Lalioti, VS; Martinez-Arca, S; Sandoval, IV | 1 |
| Araki, Y; Sendo, F; Yu, Y | 1 |
| Appleyard, SM; Chavkin, C; Pattillo, A; Rogalski, SL; Terman, GW | 1 |
| Martin, JG; Tao, FC; Tolloczko, B; Zacour, ME | 1 |
| Akaishi, Y; Hattori, Y; Kanno, M; Kitabatake, A; Yasuda, K; Yoshimoto, K | 1 |
| Cheng, EL; Rege, P; Yue, BY; Zhou, L | 1 |
| Chess, PR; Finkelstein, JN; Toia, L | 1 |
| Imaizumi, N; Kigoshi, T; Nakagawa, A; Nakano, S; Nishio, M; Uchida, K; Yoshida, J | 1 |
| Nakamura, M; Tanigawa, Y | 1 |
| Ihn, H; Tamaki, K | 2 |
| Kamisaki, Y; Maeda, S; Saeki, M | 1 |
| Chen, H; Chen, J; Dong, C; Fan, G; Guan, K; He, F; Hu, Z; Li, M; Li, Y; Wang, Q; Wei, H; Wu, C; Xing, G; Yang, X; Zhang, C; Zhao, S | 1 |
| Karlsson, AM; Lerner, MR; Lundström, I; Svensson, SP; Unett, D | 1 |
| Ali-Osman, F; Mullapudi, SR; Shou, J; Srivenugopal, KS | 1 |
| Kim, KS; Prasadarao, NV; Reddy, MA; Schlaepfer, DD; Wass, CA | 1 |
| Jow, F; Wang, K | 1 |
| Harrington, MA; Hatton, ND; Jin, N; Larsen, SH; Rhoades, RA; Xia, X | 1 |
| Garcia-Marin, LJ; Jensen, RT; Leyton, J; Moody, TW; Tapia, JA | 1 |
| Haller, H; Kettritz, R; Luft, FC; Schreiber, A | 1 |
| Haig, D; Reid, H; Swa, S; Thomson, J; Wright, H | 1 |
| Golde, DW; Núñez-Alarcón, J; Reyes, AM; Rivas, CI; Slebe, JC; Strobel, P; Velásquez, FV; Vera, JC; Zhang, RH | 1 |
| Eghbali-Webb, M; Griffin, M; Lee, HW; Zhao, L | 1 |
| Masui, H; Wakabayashi, I | 1 |
| Al-Okla, S; Chatenay-Rivauday, C; Klein, JP; Wachsmann, D | 1 |
| Fujimura, S; Hirai, K; Ishihara, K; Kato, T; Nakamura, T; Okuda, K; Shibata, Y | 1 |
| Boland, R; de Boland, AR; Gentili, C | 1 |
| Biden, TJ; Blewitt, M; Kelly, MM; Mitchell, CJ; Wilson, JR | 1 |
| Wei, L; Yang, Y; Yu, Q | 1 |
| Atkinson, KJ; Rao, RK | 1 |
| Fish, EN; Fujita, S; Grumbach, IM; Lekmine, F; Majchrzak, B; Mayer, IA; Platanias, LC; Ravandi, F; Uddin, S; Verma, A | 1 |
| Barnes, S; Kim, H; Li, L; Murphy-Ullrich, J; Peterson, G; Su, Y; Xia, H; Xu, J | 1 |
| Cui, ZC; Li, Y; Pei, L; Zhang, GY; Zhu, ZM | 1 |
| Cho, CS; Fechner, JH; Hamawy, MM; Knechtle, SJ; Manthei, ER; Tsuchida, M | 1 |
| Cho, C; Easaw, J; Harris, K; Jassar, B; Jhamandas, JH; MacTavish, D | 1 |
| Quick, MW; Whitworth, TL | 1 |
| Antonieta Cote-Vélez, MJ; Ortega, A; Ortega, E | 1 |
| Chu, AJ; Seto, A; Walton, MA; Wang, ZG | 1 |
| Nakahata, N; Nakatani, K; Ohizumi, Y; Tsurufuji, S | 1 |
| Adrian, TE; Ding, XZ; Tong, WG | 1 |
| Castranova, V; Chong, Y; Kang, JL; Koh, Y; Lee, HS; Lee, HW; Pack, IS | 1 |
| Kräusslich, HG; Müller, B; Patschinsky, T | 1 |
| Han, JS; Kim, JG; Lee, KS; Shin, I | 1 |
| Chikumi, H; Fukuhara, S; Gutkind, JS | 1 |
| Martin, S; Mazella, J; Vincent, JP | 1 |
| Cayabyab, FS; Schlichter, LC | 1 |
| Lai, HH; Yen, GC | 1 |
| Barratt, CL; Bray, C; Kirkman-Brown, JC; Lefièvre, L; Publicover, SJ; Stewart, PM | 1 |
| Harmon, AW; Harp, JB; Patel, YM | 1 |
| Fan, YP; Puri, RN; Rattan, S | 1 |
| Basuroy, S; Gupta, A; Karnaky, KJ; Rao, RK; Rao, VU | 1 |
| Finckenberg, P; Korpela, R; Lassila, M; Nevala, R; Paukku, K; Vapaatalo, H | 1 |
| Husain, S; Jafri, F | 1 |
| Hussain, T; Lokhandwala, MF; Narkar, VA | 1 |
| Belanger, PH; Filler, SG; Fratti, RA; Johnston, DA; Zhang, M | 1 |
| Chen, G; Kodama, H; Lu, H; Manabe, M; Wang, C; Yamashita, K | 1 |
| Ben-Smith, A; Dove, SK; Hewins, P; Hughes, P; McEwan, R; Savage, CO; Wakelam, MJ; Williams, JM | 1 |
| Oehrl, W; Rubio, I; Wetzker, R | 1 |
| Hill, MA; Martinez-Lemus, LA; Meininger, GA; Potocnik, SJ | 1 |
| Luxon, BA; Milliano, MT | 1 |
| Berti, E; Burlando, B; Magnelli, V; Panfoli, I; Viarengo, A | 1 |
| Chain, BM; Cho, JY; Katz, DR | 1 |
| Hoshino, T; Mima, S; Mizushima, T; Tomisato, W; Tsuchiya, T; Tsutsumi, S | 1 |
| Li, HC; Zhang, GY | 1 |
| Bergan, RC; Crowell, JA; Gallot, L; Glover, K; Goetz, A; Hayes, SA; Hernandez, L; Huang, X; Jovanovic, BD; Lieberman, R; Llorens, V; Poisson, BA; Quinn, M; Shapiro, A; Takimoto, CH | 1 |
| Oram, JF; Tang, C; Vaughan, AM | 1 |
| Han, J; Liu, XP; Yao, LB; Yu, Q | 1 |
| Capodici, J; Karikó, K; Lamphier, M; Ni, H; Weissman, D | 1 |
| Nozu, F; Tsunoda, Y; Yoshida, H | 1 |
| Berggren, PO; Köhler, M; Larsson, O; Yang, SN; Zhang, F; Zhang, Q | 1 |
| Biswas, D; Itoh, K; Niwa, H | 1 |
| Chatterjee, S; Freedman, RR; Furspan, PB | 1 |
| Collett, VJ; Collingridge, GL | 1 |
| Isobe, M; Kanakubo, A | 1 |
| Ba, X; Chen, C; Gao, Y; Zeng, X | 1 |
| Baumeister, P; Hakre, S; Hong, M; Huang, JM; Lee, AS; Lin, MY; Roy, AL | 1 |
| Ikeda, K; Xu, JW; Yamori, Y | 1 |
| Dunah, AW; Hoogenraad, CC; Hueske, E; Jaworski, J; Liu, G; Pak, DT; Sheng, M; Simonetta, A; Wyszynski, M | 1 |
| Clapp, C; de la Escalera, GM; López-Barrera, F; Macotela, Y; Montes de Oca, P; Nava, G | 1 |
| Barnes, S; Chacko, BK; Chandler, RT; Kevil, CG; Khoo, N; Kucik, DF; Mundhekar, A; Parks, DA; Patel, RP; Pruitt, HM | 1 |
| Cho, CH; Leitzell, K; Lester, RA; Meleth, AD; Quick, MW; Song, W; Teo, E | 1 |
| Judah, JD; Lo, LC; Thomas, GM; Webb, RJ | 1 |
| Hasegawa, A; Hatano, Y; Kakutani, T; Mizumoto, K; Ogawa, K; Yu, J | 1 |
| Hu, D; Liu, L; Zhou, R | 1 |
| Iversen, TG; Lauvrak, SU; Sandvig, K; Slagsvold, HH; Spilsberg, B; Torgersen, ML; Wälchli, S | 1 |
| Arruebo, MP; Grasa, L; Murillo, MD; Plaza, MA | 1 |
| Alvarez, SE; Ayub, MJ; Ciuffo, GM; Villarreal, RS | 1 |
| Funa, N; Horinouchi, S; Katsuyama, Y; Miyahisa, I | 1 |
| Capron, B; Godaux, E; Ris, L; Sindic, C; Wattiez, R | 1 |
| Carlson, AC; IJdo, JW; Kennedy, EL | 1 |
| Cheung, JY; Conrad, K; Miller, BA; Tong, Q; Wozney, J; Zhang, W | 1 |
| Li, M; Ren, H; Wang, T; Xiang, Y; Zi, H | 1 |
| Carbo, C; Diaz-Ricart, M; Escolar, G; Fuste, B; Lopez-Vilchez, I; Palomo, M; Perez-Pujol, S; White, JG | 1 |
| Janssen, LJ; Lippton, H; Liu, C; Tazzeo, T | 1 |
| Rollinson, D; Walker, AJ | 1 |
| Imai, S; Isoya, E; Kumagai, K; Matsusue, Y; Matsuura, H; Okumura, N; Toyoda, F | 1 |
| Nakaseko, C; Onoda, M; Saito, Y; Yokota, A | 1 |
| Moorhouse, AJ; Nabekura, J; Wake, H; Watanabe, M | 1 |
| Kasai, S; Kikuchi, H | 1 |
| Dong, MQ; Lau, CP; Li, GR; Sun, HY; Tang, Q; Tse, HF | 1 |
| Gruenert, DC; Hanrahan, JW; LeSimple, P; Liao, J; Robert, R | 1 |
| Gu, SH; Lin, JL | 1 |
| Gammeltoft, S; Hoffmann, EK; Kirkegaard, SS; Lambert, IH | 1 |
| Jaiswal, AK; Kaspar, JW | 1 |
| Ahn, HS; Choi, BH; Hahn, SJ; Kim, HJ | 1 |
| Hong, SJ; Ju, J; Lee, J; Park, S; Yoon, S | 1 |
| Cheng, LC; Deng, XL; Lau, CP; Li, GR; Li, X; Sun, HY; Tse, HF; Wu, W; Zhang, YH | 1 |
| Baltz, JM; Zhou, C | 1 |
| An, Y; Chen, AF; Fan, S; Han, J; Li, X; Liu, S; Tie, L; Xiao, Y; Xiaokaiti, Y | 1 |
| Gao, X; Guo, X; Huang, F; Liu, B; Liu, K; Wang, M; Zhang, D | 1 |
| Anuradha, CV; Arunkumar, E | 1 |
| Hashizume, H; Kamio, N; Matsushima, K; Muromachi, K; Nakao, S; Narita, T | 1 |
| Cai, QY; Chen, AQ; Chen, Y; Guo, LX; Lin, C; Luo, XQ; Wu, ZQ | 1 |
| Hishinuma, S; Mita, M; Nakagawa, J; Shoji, M; Sutherland, C; Tanaka, H; Walsh, MP; Yanagihara, H | 1 |
| Esatbeyoglu, T; Huebbe, P; Pallauf, K; Piegholdt, S; Reiss, K; Rimbach, G; Ruddigkeit, L; Speck, N; Stocker, A | 1 |
| Pei, DS; Qian, HY; Wang, HW; Zhang, DG; Zheng, JN | 1 |
| Ganai, AA; Husain, M | 1 |
| Chen, L; Liang, X; McBride, DW; Qin, G; Tan, G; Wang, S; Xie, J; Zhou, J | 1 |
1 review(s) available for tyrosine and genistein
| Article | Year |
|---|---|
Human topoisomerase II function, tyrosine phosphorylation and cell cycle checkpoints.
Topics: DNA Damage; DNA Topoisomerases, Type II; G1 Phase; G2 Phase; Genistein; Humans; Phosphorylation; Topoisomerase II Inhibitors; Tyrosine | 1998 |
2 trial(s) available for tyrosine and genistein
| Article | Year |
|---|---|
Phase I pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Genistein; Glycine max; Humans; Isoflavones; Male; Middle Aged; Neoplasms; Phosphorylation; Tyrosine | 2003 |
Increased tyrosine phosphorylation mediates the cooling-induced contraction and increased vascular reactivity of Raynaud's disease.
Topics: Adrenergic alpha-Agonists; Adult; Angiotensin II; Arterioles; Brimonidine Tartrate; Cold Temperature; Enzyme Inhibitors; Female; Genistein; Humans; Middle Aged; Phosphorylation; Protein-Tyrosine Kinases; Quinoxalines; Raynaud Disease; Serotonin; Signal Transduction; Skin; Skin Temperature; Tyrosine; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents | 2004 |
369 other study(ies) available for tyrosine and genistein
| Article | Year |
|---|---|
Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth.
Topics: Animals; Brain; Catechols; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Chick Embryo; Culture Media; Extracellular Matrix Proteins; Genistein; Isoflavones; Nerve Tissue Proteins; Neurites; Neurons; Nitriles; Phenols; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; Tyrosine; Tyrphostins; Vanadates | 1992 |
Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells.
Topics: Blotting, Western; Bucladesine; Cell Differentiation; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Isoflavones; Lipoproteins; Neutrophils; Pertussis Toxin; Phosphorylation; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1992 |
Oncostatin M induces tyrosine phosphorylation in endothelial cells and activation of p62yes tyrosine kinase.
Topics: Benzoquinones; Cells, Cultured; Cytokines; Endothelium, Vascular; Enzyme Activation; Genistein; Humans; Interleukin-6; Isoflavones; Lactams, Macrocyclic; Oncostatin M; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Quinones; Receptors, Cell Surface; Receptors, Cytokine; Receptors, Oncostatin M; Rifabutin; src-Family Kinases; Tyrosine | 1992 |
Tyrosine kinase regulation of a molluscan circadian clock.
Topics: Animals; Arsenicals; Biological Clocks; Circadian Rhythm; Ethers, Cyclic; Eye; Genistein; Isoflavones; Okadaic Acid; Phosphates; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Snails; Tyrosine | 1992 |
Activation of natural killer cells via the Fc gamma RIII (CD16) requires initial tyrosine phosphorylation.
Topics: Antibody-Dependent Cell Cytotoxicity; Antigens, Differentiation; Cytotoxicity, Immunologic; Genistein; Inositol Phosphates; Isoflavones; Killer Cells, Natural; Lymphocyte Activation; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fc; Receptors, IgG; Signal Transduction; Tyrosine | 1992 |
Fc epsilon RI-induced protein tyrosine phosphorylation of pp72 in rat basophilic leukemia cells (RBL-2H3). Evidence for a novel signal transduction pathway unrelated to G protein activation and phosphatidylinositol hydrolysis.
Topics: 3T3 Cells; Animals; Antigens, Differentiation, B-Lymphocyte; Carbachol; Cell Line; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoglobulin E; Inositol Phosphates; Isoflavones; Kinetics; Leukemia, Basophilic, Acute; Mice; Models, Biological; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Receptors, Muscarinic; Signal Transduction; Transfection; Type C Phospholipases; Tyrosine | 1992 |
High-affinity IgE receptor-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells induces early and late protein-tyrosine phosphorylations.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Basophils; Biological Transport; Blotting, Western; Calcimycin; Calcium; Electrophoresis, Polyacrylamide Gel; Genistein; Histamine Release; Immunoglobulin E; Isoflavones; Leukemia, Basophilic, Acute; Mast Cells; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Rats; Receptors, Fc; Receptors, IgE; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1992 |
Tyrosine phosphorylation is required for mast cell activation by Fc epsilon RI cross-linking.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cross-Linking Reagents; Genistein; Histamine Release; Immunoglobulin E; Inositol 1,4,5-Trisphosphate; Isoflavones; Mast Cells; Mice; Mice, Inbred CBA; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fc; Receptors, IgE; Signal Transduction; Type C Phospholipases; Tyrosine | 1992 |
Recombinant human interleukin-9 induces protein tyrosine phosphorylation and synergizes with steel factor to stimulate proliferation of the human factor-dependent cell line, M07e.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Genistein; Hematopoietic Cell Growth Factors; Humans; Immunoblotting; Interleukin-9; Isoflavones; Kinetics; Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Stem Cell Factor; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Role of tyrosyl phosphorylation in neutrophil priming by tumor necrosis factor-alpha and granulocyte colony stimulating factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Blotting, Western; Cell Membrane; Cytosol; Genistein; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Isoflavones; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 1992 |
Interferon alpha induces rapid tyrosine phosphorylation of the alpha subunit of its receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Blotting, Western; Dose-Response Relationship, Drug; Genistein; Humans; Interferon Type I; Isoflavones; Isoquinolines; Kinetics; Macromolecular Substances; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Interferon; Recombinant Proteins; Time Factors; Tumor Cells, Cultured; Tyrosine | 1992 |
Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake.
Topics: Alkaloids; Cell Membrane; Cytoskeleton; Epithelium; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Genistein; HeLa Cells; Humans; Isoflavones; Kinetics; Models, Biological; Molecular Weight; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tyrosine | 1992 |
Tyrosine phosphorylation is an early and requisite signal induced by interferon-gamma in HL-60 cells.
Topics: Benzoquinones; Genistein; Interferon-gamma; Isoflavones; Lactams, Macrocyclic; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Receptors, Fc; Rifabutin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1992 |
PDGF induces tyrosine phosphorylation in osteoblast-like cells: relevance to mitogenesis.
Topics: Animals; Cell Line; Genistein; Isoflavones; Mitosis; Osteoblasts; Phosphorylation; Platelet-Derived Growth Factor; Thymidine; Tyrosine; Vanadates | 1992 |
Erythropoietin induces p21ras activation and p120GAP tyrosine phosphorylation in human erythroleukemia cells.
Topics: Electrophoresis, Polyacrylamide Gel; Erythropoietin; Genistein; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Isoflavones; Leukemia, Erythroblastic, Acute; Oncogene Protein p21(ras); Phosphorylation; Proteins; ras GTPase-Activating Proteins; Recombinant Proteins; Signal Transduction; Tyrosine | 1992 |
Tyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiation.
Topics: Animals; Blotting, Western; Calcium; Cell Differentiation; Cytoskeleton; Cytosol; Genistein; Isoflavones; Keratinocytes; Mice; Mice, Inbred Strains; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transglutaminases; Tyrosine | 1990 |
Platelet-activating factor stimulation of tyrosine kinase and its relationship to phospholipase C in rabbit platelets: studies with genistein and monoclonal antibody to phosphotyrosine.
Topics: Animals; Antibodies, Monoclonal; Blood Platelets; Blotting, Western; Flavonoids; Genistein; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tritium; Type C Phospholipases; Tyrosine | 1990 |
The role of tyrosine phosphorylation in signal transduction through surface Ig in human B cells. Inhibition of tyrosine phosphorylation prevents intracellular calcium release.
Topics: Aluminum; Aluminum Compounds; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Benzoquinones; Calcium; CD40 Antigens; Cell Line; Cross-Linking Reagents; Fluorides; Genistein; Humans; Immunoglobulin M; Isoflavones; Lactams, Macrocyclic; Models, Biological; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Receptors, Antigen, B-Cell; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine | 1991 |
Interleukin-6 signals activating junB and TIS11 gene transcription in a B-cell hybridoma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; B-Lymphocytes; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation; Genistein; Hybridomas; Immediate-Early Proteins; In Vitro Techniques; Interleukin-6; Isoflavones; Isoquinolines; Lymphocyte Activation; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Tristetraprolin; Tyrosine | 1991 |
Effect of genistein, a tyrosine kinase inhibitor, on latent EBV activation induced by cross-linkage of membrane IgG in Akata B cells.
Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line; Cross-Linking Reagents; DNA-Binding Proteins; Gene Expression Regulation, Viral; Genistein; Herpesvirus 4, Human; Humans; Immunoglobulin G; In Vitro Techniques; Isoflavones; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor Aggregation; Receptors, Antigen, B-Cell; Trans-Activators; Tyrosine; Viral Proteins | 1991 |
Intracellular localization of tyrosine kinase substrates beneath crosslinked surface immunoglobulins in B cells.
Topics: Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Line; Cross-Linking Reagents; Cytoplasm; Fluorescent Antibody Technique; Genistein; Humans; Immunoglobulin G; Isoflavones; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; Tyrosine | 1991 |
Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product.
Topics: Blotting, Northern; Cell Division; Gene Expression; Genistein; Hematopoietic Cell Growth Factors; Humans; Immunologic Techniques; Isoflavones; Leukemia, Myeloid; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Recombinant Proteins; Stem Cell Factor; Tumor Cells, Cultured; Tyrosine | 1991 |
Tyrosine phosphorylation and immunodetection of vinculin in growth cone particle (GCP) fraction and in GCP-cytoskeletal subfractions.
Topics: Animals; Antibodies, Monoclonal; Brain; Calcium; Cytoskeleton; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fetus; Genistein; Isoflavones; Molecular Weight; Neurons; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Synaptosomes; Tyrosine; Vinculin | 1991 |
Tyrosine phosphorylation selectively regulates renal cellular phosphate transport. Evidence that it mediates the stimulatory effect of insulin-like growth factor-1.
Topics: Animals; Biological Transport; Cells, Cultured; Dose-Response Relationship, Drug; Genistein; Insulin-Like Growth Factor I; Isoflavones; Kidney; Opossums; Phosphates; Phosphorylation; Protein Biosynthesis; Protein-Tyrosine Kinases; Sodium; Tyrosine; Vanadates | 1992 |
Human IL-3 induction of c-jun in normal monocytes is independent of tyrosine kinase and involves protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Enzyme Activation; Gene Expression Regulation; Genes, jun; Genistein; Humans; Interleukin-3; Isoflavones; Isoquinolines; Monocytes; Phosphorylation; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1992 |
NGF and EGF rapidly activate p21ras in PC12 cells by distinct, convergent pathways involving tyrosine phosphorylation.
Topics: Animals; Carbazoles; Epidermal Growth Factor; Genistein; Guanosine Diphosphate; Guanosine Triphosphate; Indole Alkaloids; Isoflavones; Kinetics; Nerve Growth Factors; PC12 Cells; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Tyrosine | 1991 |
A cyclin-abundance cycle-independent p34cdc2 tyrosine phosphorylation cycle in early sea urchin embryos.
Topics: Animals; Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Cross Reactions; Cyclins; Electrophoresis, Polyacrylamide Gel; Emetine; Genistein; Isoflavones; Mitosis; Ovum; Phosphorylation; Protein-Tyrosine Kinases; Sea Urchins; Tyrosine | 1991 |
Genistein, a protein tyrosine kinase inhibitor, inhibits thromboxane A2-mediated human platelet responses.
Topics: Anti-Bacterial Agents; Benzoquinones; Blood Platelets; Cinnamates; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Phospholipids; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serotonin; Signal Transduction; Sulfides; Thromboxane A2; Tyrosine | 1991 |
T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation.
Topics: Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Humans; Hydrolysis; Isoflavones; Lymphocyte Activation; Ornithine Decarboxylase; Phospholipids; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; T-Lymphocytes; Type C Phospholipases; Tyrosine | 1990 |
Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein.
Topics: Cell Differentiation; DNA; DNA Damage; DNA Topoisomerases, Type II; Flavonoids; Genistein; Humans; Isoflavones; Leukemia; Molecular Weight; Phosphorylation; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tyrosine | 1990 |
The nuclear matrix from rat liver is capable of phosphorylating exogenous tyrosine-containing substrates.
Topics: Adenosine Triphosphate; Amino Acids; Angiotensin II; Animals; Catalysis; Cell Nucleus; Genistein; Isoflavones; Kinetics; Liver; Magnesium; Manganese; Phosphorylation; Protein-Tyrosine Kinases; Rats; Tyrosine | 1989 |
Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Division; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, fos; Genistein; Isoflavones; Lactams, Macrocyclic; Male; Muscle Proteins; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Inbred BN; Receptors, Angiotensin; Rifabutin; RNA, Messenger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transcriptional Activation; Type C Phospholipases; Tyrosine | 1995 |
Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland.
Topics: Animals; Cells, Cultured; Chlorides; Cyclic AMP; Genistein; Isoflavones; Male; Peptides; Perfusion; Phosphorylation; Salt Gland; Sharks; Tyrosine | 1995 |
The role of tyrosine phosphorylation and Ca2+ accumulation in Fc gamma-receptor-mediated phagocytosis of human neutrophils.
Topics: Antigen-Antibody Complex; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fluorescence; Genistein; Humans; Immunoblotting; Immunoglobulin G; Isoflavones; Neutrophils; Phagocytosis; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Fc; Tetanus Toxin; Tyrosine | 1995 |
Cross-linking of CD18 primes human neutrophils for activation of the respiratory burst in response to specific stimuli: implications for adhesion-dependent physiological responses in neutrophils.
Topics: CD18 Antigens; Cell Adhesion; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoflavones; Leukocyte Common Antigens; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Respiratory Burst; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Human bradykinin B2 receptors isolated by receptor-specific monoclonal antibodies are tyrosine phosphorylated.
Topics: Antibodies, Monoclonal; Bradykinin; Cells, Cultured; Chromatography, Affinity; Dinoprostone; Genistein; Humans; In Vitro Techniques; Isoflavones; Phosphotyrosine; Receptors, Bradykinin; Signal Transduction; Tyrosine | 1993 |
Up-regulation of a thymic epithelial ligand after contact with thymocytes.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Down-Regulation; Epithelial Cells; Genistein; In Vitro Techniques; Isoflavones; Ligands; Phosphotyrosine; Signal Transduction; T-Lymphocytes; Thymus Gland; Tyrosine; Up-Regulation | 1994 |
Thyroid cell spreading and focal adhesion formation depend upon protein tyrosine phosphorylation and actin microfilaments.
Topics: Actin Cytoskeleton; Actins; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Colchicine; Cytochalasin B; Fluorescent Antibody Technique; Genistein; Heparin; Isoflavones; Kinetics; Phosphotyrosine; Protein-Tyrosine Kinases; Swine; Thyroid Gland; Tyrosine; Vinculin | 1994 |
Cytosolic Ca2+ transients are not required for platelet-derived growth factor to induce cell cycle progression of vascular smooth muscle cells in primary culture. Actions of tyrosine kinase.
Topics: Angiotensin II; Animals; Caffeine; Calcium; Cell Cycle; Cells, Cultured; Cytosol; Genistein; Isoflavones; Male; Muscle, Smooth, Vascular; Nitriles; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Ryanodine; Second Messenger Systems; Signal Transduction; Tyrosine | 1994 |
Effect of herbimycin A, an inhibitor of tyrosine kinase, on protein tyrosine kinase activity and phosphotyrosyl proteins of Ph1-positive leukemia cells.
Topics: Antibiotics, Antineoplastic; Benzoquinones; Fusion Proteins, bcr-abl; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasm Proteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tumor Cells, Cultured; Tyrosine | 1994 |
Multiple inhibitory effects of genistein on stimulus-secretion coupling in rat pancreatic acini.
Topics: Amylases; Animals; Biological Transport; Calcium; Cholecystokinin; Genistein; Hydrolysis; Isoflavones; Pancreas; Phosphatidylinositols; Phosphorylation; Rats; Rats, Sprague-Dawley; Tyrosine | 1994 |
A tyrosine phosphorylation requirement for cytotoxic T lymphocyte degranulation.
Topics: Animals; Arsenicals; Calcium; Clone Cells; Concanavalin A; Fatty Acids, Nonesterified; Genistein; Ionomycin; Isoflavones; Kinetics; Lymphocyte Activation; Mice; Molecular Weight; Oleic Acid; Oleic Acids; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Defective asialoglycoprotein receptor endocytosis mediated by tyrosine kinase inhibitors. Requirement for a tyrosine in the receptor internalization signal.
Topics: Adenosine Triphosphate; Alkaloids; Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Catechols; Cell Line; Endocytosis; Genistein; Humans; Isoflavones; Kinetics; Liver Neoplasms; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Staurosporine; Transferrin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line.
Topics: Animals; Benzoquinones; Catechols; Cell Division; Cell Line; Genistein; Interleukin-3; Interleukin-4; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Leukotrienes; Mast-Cell Sarcoma; Mice; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Strong increase in the tyrosine phosphorylation of actin upon inhibition of oxidative phosphorylation: correlation with reversible rearrangements in the actin skeleton of Dictyostelium cells.
Topics: Actins; Adenosine Triphosphate; Animals; Arsenicals; Cytoskeleton; Dictyostelium; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Genistein; Growth Inhibitors; Isoflavones; Microscopy, Fluorescence; Oxidative Phosphorylation; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1994 |
CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Benzoquinones; Burkitt Lymphoma; CD40 Antigens; Cell Line; Cell Line, Transformed; Enzyme Precursors; Genistein; Herpesvirus 4, Human; Humans; Intracellular Signaling Peptides and Proteins; Isoflavones; Isoquinolines; Lactams, Macrocyclic; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Weight; Palatine Tonsil; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quinones; Rifabutin; Sulfonamides; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 1994 |
In human neutrophils the binding to immunocomplexes induces the tyrosine phosphorylation of Fc gamma RII but this phosphorylation is not an essential signal for Fc-mediated phagocytosis.
Topics: Antigen-Antibody Complex; Genistein; Humans; Hydroquinones; In Vitro Techniques; Isoflavones; Neutrophils; Phagocytosis; Phosphorylation; Phosphotyrosine; Receptors, IgG; Tyrosine | 1994 |
Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.
Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Isoflavones; Lysophospholipids; Mice; Models, Biological; Myosins; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1994 |
Tyrosine phosphorylation of phospholipase C-gamma 2 is involved in the activation of phosphoinositide hydrolysis by Fc receptors in human neutrophils.
Topics: Genistein; Humans; Isoenzymes; Isoflavones; Neutrophils; Phosphatidylinositols; Phosphoproteins; Phosphotyrosine; Receptor Aggregation; Receptors, Fc; Signal Transduction; Time Factors; Type C Phospholipases; Tyrosine | 1994 |
Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity.
Topics: Antibodies; Benzoquinones; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Cell Movement; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Hyaluronan Receptors; Hyaluronic Acid; Isoflavones; Lactams, Macrocyclic; Microinjections; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Receptor, Insulin; Receptors, Cell Surface; Receptors, Lymphocyte Homing; Rifabutin; Signal Transduction; Tyrosine; Vinculin | 1994 |
Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase.
Topics: Animals; Cells, Cultured; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Enzymologic; Genistein; Interleukin-3; Isoflavones; Mice; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tyrosine | 1994 |
Phosphotyrosine inhibition and control of vascular endothelial cell proliferation by genistein.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; DNA; Endothelium, Vascular; Fibroblast Growth Factor 2; Genistein; Isoflavones; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Tyrosine | 1994 |
Salmonella typhimurium invasion of epithelial cells: role of induced host cell tyrosine protein phosphorylation.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Epithelium; Genistein; HeLa Cells; Humans; In Vitro Techniques; Isoflavones; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Salmonella Infections; Salmonella typhimurium; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1994 |
Prevention of anti-CD3 monoclonal antibody-induced thymic apoptosis by protein tyrosine kinase inhibitors.
Topics: Animals; Apoptosis; Benzoquinones; CD3 Complex; Clonal Deletion; Dexamethasone; Genistein; Isoflavones; Lactams, Macrocyclic; Mice; Mice, Inbred BALB C; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quinones; Rifabutin; T-Lymphocyte Subsets; Thymus Gland; Tyrosine | 1994 |
Signaling via CD7 molecules on human NK cells. Induction of tyrosine phosphorylation and beta 1 integrin-mediated adhesion to fibronectin.
Topics: Alkaloids; Amino Acid Sequence; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Adhesion; Cytochalasin B; Enzyme Activation; Fibronectins; Genistein; Humans; In Vitro Techniques; Integrins; Isoflavones; Killer Cells, Natural; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fibronectin; Receptors, IgG; Receptors, Immunologic; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Mitogenic signaling of thrombin in mesangial cells: role of tyrosine phosphorylation.
Topics: Benzoquinones; Calcium; Cells, Cultured; Cysteine; DNA; Gene Expression; Genistein; Glomerular Mesangium; Humans; Immunoblotting; Inositol Phosphates; Isoflavones; Lactams, Macrocyclic; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Sulfur Radioisotopes; Thrombin; Tyrosine | 1994 |
Reversion of the transformed phenotypes of v-H-ras NIH3T3 cells by flavonoids through attenuating the content of phosphotyrosine.
Topics: 3T3 Cells; Animals; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chamomile; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Flavonoids; Genes, ras; Genistein; Isoflavones; Kaempferols; Mice; Oils, Volatile; Phenotype; Phosphotyrosine; Plants, Medicinal; Protein-Tyrosine Kinases; Quercetin; Tyrosine | 1994 |
Tyrosine kinase inhibitors inhibit glucose-stimulated insulin secretion.
Topics: Animals; Catechols; Genistein; Glucose; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Isoflavones; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Tyrosine; Tyrphostins | 1994 |
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
Topics: Cell Adhesion; Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Genistein; Glycoproteins; Humans; Insulin-Like Growth Factor I; Integrins; Isoflavones; Kinetics; Naphthalenes; Nitriles; Pancreatic Neoplasms; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vitronectin | 1994 |
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.
Topics: Apoptosis; Arsenicals; Eosinophils; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoflavones; Neutrophils; Phosphoprotein Phosphatases; Phosphotyrosine; Signal Transduction; Tyrosine | 1994 |
Cell cycle-specific induction of an 89 kDa serine/threonine protein kinase activity in Trypanosoma brucei.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Catechols; Cell Cycle; Cell Division; Cycloheximide; DNA; Enzyme Induction; Ethers, Cyclic; Flow Cytometry; Genistein; Isoflavones; Isoquinolines; Molecular Weight; Nitriles; Okadaic Acid; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Denaturation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; S Phase; Staurosporine; Trypanosoma brucei brucei; Tyrosine; Tyrphostins | 1994 |
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
Topics: Animals; Caseins; Cell Aggregation; Cells, Cultured; Extracellular Matrix; Female; Gene Expression Regulation, Developmental; Genistein; In Vitro Techniques; Integrins; Isoflavones; Mice; Phosphotyrosine; Prolactin; Receptor Aggregation; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1994 |
Tyrosine kinase activity is necessary for growth factor-stimulated rabbit type II pneumocyte proliferation.
Topics: Adenocarcinoma; Animals; Blotting, Western; Catechols; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Isoflavones; Kinetics; Lung; Male; Molecular Weight; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Acute neurite retraction triggered by lysophosphatidic acid: timing of the inhibitory effects of genistein.
Topics: Actins; Animals; Genistein; Glioma; Hybrid Cells; Immunohistochemistry; Isoflavones; Kinetics; Lysophospholipids; Mice; Neurites; Neuroblastoma; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Time Factors; Tyrosine | 1994 |
Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6).
Topics: Animals; Cell Count; Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Genistein; Inositol Phosphates; Intestinal Mucosa; Isoenzymes; Isoflavones; Membrane Proteins; Phospholipase C gamma; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Time Factors; Type C Phospholipases; Tyrosine | 1995 |
Resistance of melanoma cell lines to interferons correlates with reduction of IFN-induced tyrosine phosphorylation. Induction of the anti-viral state by IFN is prevented by tyrosine kinase inhibitors.
Topics: 2',5'-Oligoadenylate Synthetase; Antiviral Agents; Benzoquinones; Drug Resistance; Genistein; GTP-Binding Proteins; Humans; Interferons; Isoflavones; Lactams, Macrocyclic; Melanoma; Myxovirus Resistance Proteins; Neoplasm Proteins; Phosphorylation; Protein Biosynthesis; Protein-Tyrosine Kinases; Quinones; Rifabutin; Semliki forest virus; Tumor Cells, Cultured; Tyrosine | 1995 |
Tyrosine phosphorylation induced by cross-linking of Fc gamma-receptor type II in human neutrophils.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cross-Linking Reagents; Egtazic Acid; Ethers, Cyclic; Genistein; Humans; Isoflavones; Molecular Sequence Data; Neutrophils; Okadaic Acid; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, IgG; Respiratory Burst; Tyrosine; Virulence Factors, Bordetella | 1995 |
Transforming growth factor-beta 1 induction of novel extracellular matrix proteins that trigger resistance to tumor necrosis factor cytotoxicity in murine L929 fibroblasts.
Topics: Alkaloids; Animals; Catechols; Cell Survival; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Fibroblasts; Genistein; Isoflavones; Kinetics; L Cells; Mice; Nitriles; Phenols; Phosphotyrosine; Protein Kinase Inhibitors; Staurosporine; Transforming Growth Factor beta; Tumor Protein, Translationally-Controlled 1; Tyrosine; Tyrphostins | 1995 |
Priming of human neutrophils by tumour necrosis factor-alpha and substance P is associated with tyrosine phosphorylation.
Topics: Genistein; Humans; Immunohistochemistry; Isoflavones; Neutrophils; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Substance P; Tumor Necrosis Factor-alpha; Tyrosine | 1995 |
Bradykinin induces tyrosine phosphorylation of epidermal growth factor-receptor and focal adhesion proteins in human keratinocytes.
Topics: Alkaloids; Bradykinin; Cell Adhesion Molecules; Cell Line; Chromatography, Affinity; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Immunoblotting; Indoles; Isoflavones; Keratinocytes; Maleimides; Molecular Weight; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Bradykinin; Staurosporine; Tyrosine | 1995 |
Carbachol, substance P, and phorbol ester promote the tyrosine phosphorylation of protein kinase C delta in salivary gland epithelial cells.
Topics: Alkaloids; Animals; Biological Transport; Carbachol; Cell Membrane; Cells, Cultured; Enzyme Activation; Epithelial Cells; Epithelium; ErbB Receptors; Genistein; Isoenzymes; Isoflavones; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Receptor, Insulin; Salivary Glands; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Cisplatin stimulates protein tyrosine phosphorylation in macrophages.
Topics: Animals; Cell Line; Cisplatin; Enzyme Activation; Fluorescent Antibody Technique; Genistein; Isoflavones; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1995 |
Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabsyl derivatization.
Topics: Cell Extracts; Chromatography, Thin Layer; Electrophoresis; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; p-Dimethylaminoazobenzene; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Hydrolysates; Protein-Tyrosine Kinases; Quercetin; Tumor Cells, Cultured; Tyrosine | 1995 |
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Hypoxia; Endothelial Growth Factors; Genistein; Isoflavones; Lymphokines; Mice; Molecular Sequence Data; Neovascularization, Pathologic; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); RNA, Messenger; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase.
Topics: Benzoquinones; Cell Adhesion; Cell Adhesion Molecules; Enzyme Activation; Enzyme Precursors; Extracellular Matrix Proteins; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, Reporter; Genistein; Humans; Inflammation; Integrin beta1; Integrins; Interleukin-1; Intracellular Signaling Peptides and Proteins; Isoflavones; Lactams, Macrocyclic; Leukemia, Monocytic, Acute; Monocytes; NF-kappa B; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Signal Transduction; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 1995 |
Ligation of the alpha 2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH.
Topics: alpha-Macroglobulins; Animals; Cells, Cultured; Cytosol; Epidermal Growth Factor; Genistein; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Isoenzymes; Isoflavones; Lactoferrin; Low Density Lipoprotein Receptor-Related Protein-1; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Phospholipase C gamma; Phosphorylation; Rats; Receptors, Immunologic; Type C Phospholipases; Tyrosine | 1995 |
Amiloride suppresses erythropoietin-induced proliferation and MAP kinase, but potentiates differentiation of J2E cells.
Topics: Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Erythropoietin; Genistein; Hemoglobins; Humans; Immunoblotting; Isoflavones; Kinetics; Leucine; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Thymidine; Tyrosine | 1995 |
Induction of macrophage procoagulant activity by murine hepatitis virus strain 3: role of tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Catechols; Cells, Cultured; Female; Genistein; Hepatitis, Viral, Animal; Isoflavones; Kinetics; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Murine hepatitis virus; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine; Tyrphostins | 1995 |
Receptor-activated increases in intracellular calcium and protein tyrosine phosphorylation in vascular smooth muscle cells.
Topics: Animals; Calcium; Cells, Cultured; Dogs; Femoral Artery; Fura-2; Genistein; Isoflavones; Muscle, Smooth, Vascular; Nitriles; Phenylephrine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Tyrosine | 1995 |
Cross-linking of CD45 on NK cells stimulates p56lck-mediated tyrosine phosphorylation and IFN-gamma production.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cytotoxicity, Immunologic; Enzyme Activation; Enzyme Inhibitors; Genistein; Interferon-gamma; Isoflavones; Killer Cells, Natural; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphorylation; Receptors, IgG; src-Family Kinases; Tyrosine; Vanadates | 1995 |
IL-1 beta regulates rat mesangial cyclooxygenase II gene expression by tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Cells, Cultured; Dinoprostone; Gene Expression Regulation, Enzymologic; Genistein; Glomerular Mesangium; Interleukin-1; Isoflavones; Lactams, Macrocyclic; Male; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; RNA, Messenger; Tyrosine; Vanadates | 1995 |
Influence of protein tyrosine phosphorylation on the expression of the c-myc oncogene in cancer of the large bowel.
Topics: Benzoquinones; Cell Count; Cell Line; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Genistein; Half-Life; Humans; Isoflavones; Lactams, Macrocyclic; Novobiocin; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; RNA, Messenger; Topoisomerase II Inhibitors; Tyrosine; Vanadates | 1995 |
Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages.
Topics: Actins; Animals; Female; Fluorescent Antibody Technique; Genistein; In Vitro Techniques; Isoflavones; Macrophages; Mice; Mice, Inbred C57BL; Phagocytosis; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Fc; Tyrosine | 1993 |
Inhibition of tyrosine phosphorylation prevents IFN-gamma-induced HLA-DR molecule expression.
Topics: Benzoquinones; Calcimycin; Calcium; Genistein; HLA-DR Antigens; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Interferon-gamma; Isoflavones; Lactams, Macrocyclic; Nitriles; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1993 |
Stimulation of human neutrophils with formyl-methionyl-leucyl-phenylalanine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases.
Topics: Amino Acid Sequence; Blotting, Western; Cell Compartmentation; Enzyme Activation; ErbB Receptors; Genistein; Humans; Isoflavones; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Respiratory Burst; Tyrosine | 1993 |
Genistein, a tyrosine kinase inhibitor, blocks the cell cycle progression but not Ca2+ influx induced by BAY K8644 in FRTL-5 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Cell Cycle; DNA; Genistein; Insulin-Like Growth Factor I; Isoflavones; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Thyrotropin; Time Factors; Tyrosine | 1993 |
Involvement of tyrosine phosphorylation in IgE receptor-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antigens; Basophils; Cinnamates; Enzyme Activation; Genistein; Immunoglobulin E; In Vitro Techniques; Isoflavones; Leukemia, Basophilic, Acute; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; Sulfides; Tumor Cells, Cultured; Tyrosine | 1993 |
Direct stimulation by tyrosine phosphorylation of microtubule-associated protein (MAP) kinase activity by granulocyte-macrophage colony-stimulating factor in human neutrophils.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Ion Exchange; Ethers, Cyclic; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Isoflavones; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine | 1993 |
Murine T-lymphocyte proliferation induced by interleukin 2 correlates with a transient increase in p56lck kinase activity and the tyrosine phosphorylation of a 97-kDa protein.
Topics: Animals; Blotting, Northern; Dose-Response Relationship, Drug; Enzyme Activation; Genes, myc; Genistein; Humans; Interleukin-2; Isoflavones; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Mice; Mice, Inbred C57BL; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; RNA, Messenger; RNA, Ribosomal, 18S; T-Lymphocytes; Thymidine; Tyrosine | 1993 |
A cytosolic activator of DNA replication is tyrosine phosphorylated in its active form.
Topics: Aprotinin; Cytosol; DNA Replication; Dose-Response Relationship, Drug; Flavonoids; Genistein; Humans; In Vitro Techniques; Isoflavones; Kaempferols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Signal Transduction; Tyrosine | 1993 |
Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors.
Topics: Barium; Bradykinin; Calcium; Calcium-Transporting ATPases; Catechols; Cells, Cultured; Fibroblasts; Fura-2; Genistein; Humans; Immunoblotting; Isoflavones; Kinetics; Male; Nitriles; Phosphotyrosine; Protein-Tyrosine Kinases; Skin; Terpenes; Thapsigargin; Tyrosine; Tyrphostins | 1993 |
Reversible priming and protein-tyrosyl phosphorylation in human peripheral neutrophils under hypotonic conditions.
Topics: Amino Acid Sequence; Genistein; Humans; Isoflavones; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmotic Pressure; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Superoxides; Tyrosine | 1993 |
Increased neurite outgrowth induced by inhibition of protein tyrosine kinase activity in PC12 pheochromocytoma cells.
Topics: Adenosine Triphosphate; Animals; Catechols; Cell Differentiation; Cell Division; Electrophoresis, Polyacrylamide Gel; Genistein; Isoflavones; Kinetics; Molecular Weight; Nerve Growth Factors; Neurites; Nitriles; PC12 Cells; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Receptor, trkA; Tyrosine; Tyrphostins; Video Recording | 1993 |
Stimulation of protein tyrosine phosphorylation by a progesterone receptor on the cell surface of human sperm.
Topics: Adenosine Triphosphate; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Genistein; Humans; Isoflavones; Male; Phosphoproteins; Phosphorylation; Phosphotyrosine; Progesterone; Protein-Tyrosine Kinases; Receptors, Progesterone; Serum Albumin, Bovine; Spermatozoa; Tyrosine | 1993 |
Stem cell factor-induced signal transduction in rat mast cells. Activation of phospholipase D but not phosphoinositide-specific phospholipase C in c-kit receptor stimulation.
Topics: Animals; Antigens; Diglycerides; Genistein; Hematopoietic Cell Growth Factors; Isoflavones; Mast Cells; Peritoneal Cavity; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phosphotyrosine; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Rats; Rats, Wistar; Second Messenger Systems; Secretory Rate; Serotonin; Signal Transduction; Stem Cell Factor; Type C Phospholipases; Tyrosine | 1993 |
Zymosan-induced tyrosine phosphorylations in human monocytes. Role of protein kinase C.
Topics: Catechols; Genistein; Humans; In Vitro Techniques; Isoflavones; Molecular Weight; Monocytes; Naphthalenes; Nitriles; Phosphoproteins; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Tyrosine; Tyrphostins; Vanadium; Zymosan | 1993 |
Vanadate-induced contraction of smooth muscle and enhanced protein tyrosine phosphorylation.
Topics: Animals; Calcium; Genistein; Guinea Pigs; Intestine, Large; Isoflavones; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosins; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1993 |
ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Blood Proteins; Calcium; Calcium-Transporting ATPases; Cinnamates; Fluorescent Dyes; Fura-2; Genistein; Humans; In Vitro Techniques; Isoflavones; Kinetics; Phosphotyrosine; Protein-Tyrosine Kinases; Terpenes; Thapsigargin; Time Factors; Tyrosine | 1993 |
The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Aggregation; Cell Movement; Cell Size; Epidermal Growth Factor; ErbB Receptors; Genistein; Hepatocyte Growth Factor; Isoflavones; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Recombinant Fusion Proteins; Signal Transduction; Tyrosine | 1993 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.
Topics: Benzoquinones; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Genistein; Humans; Hypotonic Solutions; Intestines; Iodides; Isoflavones; Kinetics; Lactams, Macrocyclic; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Rubidium; Tyrosine; Vanadates; Water-Electrolyte Balance | 1993 |
Regulated tyrosine phosphorylation at the tips of growth cone filopodia.
Topics: Animals; Aplysia; Cytoskeleton; Genistein; Hemolymph; Isoflavones; Neurons; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1993 |
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
Topics: Alkaloids; Amyloid; Carbachol; Cell Line; Genistein; Humans; Isoflavones; Phosphorylation; Prion Proteins; Prions; Protein Kinase Inhibitors; Protein Precursors; Protein Tyrosine Phosphatases; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Tyrosine kinase inhibition reduces the plateau phase of the calcium increase in response to progesterone in human sperm.
Topics: Biological Transport; Calcium; Calcium-Transporting ATPases; Genistein; Humans; Isoflavones; Male; Phosphorylation; Progesterone; Protein-Tyrosine Kinases; Spermatozoa; Terpenes; Thapsigargin; Tyrosine; Vanadates | 1995 |
Stimulation of protein tyrosine phosphorylation by platelet-activating factor and progesterone in human spermatozoa.
Topics: Acrosome; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Hydroquinones; Isoflavones; Male; Phosphorylation; Platelet Activating Factor; Progesterone; Protein-Tyrosine Kinases; Sperm Capacitation; Spermatozoa; Tyrosine | 1995 |
Tyrosine dephosphorylation and concurrent inactivation of protein kinase FA/GSK-3 alpha by genistein in A431 cells.
Topics: Amino Acid Sequence; Animals; Antibodies; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Genistein; Glycogen Synthase Kinase 3; Humans; Immunoblotting; Isoflavones; Molecular Sequence Data; Molecular Weight; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Swine; Tumor Cells, Cultured; Tyrosine | 1994 |
Platelet shape change induced by thrombin receptor activation. Rapid stimulation of tyrosine phosphorylation of novel protein substrates through an integrin- and Ca(2+)-independent mechanism.
Topics: Amino Acid Sequence; Blood Platelets; Calcium; Catechols; Cell Adhesion Molecules; Cyclic AMP; Cyclic GMP; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Integrins; Isoflavones; Molecular Sequence Data; Nitriles; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Receptors, Thrombin; Tyrosine; Tyrphostins; Vinculin | 1995 |
Role of tyrosine kinase in the regulation of myogenin expression.
Topics: Animals; Cell Differentiation; Cell Line; Gene Expression Regulation; Genistein; Isoflavones; Mice; Muscles; Myogenin; Phosphorylation; Protein-Tyrosine Kinases; Transcriptional Activation; Tyrosine | 1995 |
Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.
Topics: Alkaloids; Amino Acid Sequence; Animals; Caseins; Cells, Cultured; DNA; DNA-Binding Proteins; Genistein; Isoflavones; Janus Kinase 2; Milk Proteins; Models, Molecular; Molecular Sequence Data; Phosphorylation; Prolactin; Protein Binding; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Prolactin; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine | 1994 |
Protein tyrosine kinase activity is essential for Fc gamma receptor-mediated intracellular killing of Staphylococcus aureus by human monocytes.
Topics: Blood Bactericidal Activity; Calcium; Genistein; Humans; Inositol 1,4,5-Trisphosphate; Isoflavones; Monocytes; Protein-Tyrosine Kinases; Receptors, IgG; Respiratory Burst; Staphylococcus aureus; Superoxides; Type C Phospholipases; Tyrosine | 1994 |
Transforming growth factor-alpha increases tyrosine phosphorylation of microtubule-associated protein kinase in a small intestinal crypt cell line (IEC-6).
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Cell Line; Chemical Fractionation; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Growth Inhibitors; Intestine, Small; Isoflavones; Molecular Weight; Nitriles; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Thymidine; Transforming Growth Factor alpha; Tyrosine; Tyrphostins | 1994 |
Tyrosine phosphorylation and activation of NADPH oxidase in human neutrophils: a possible role for MAP kinases and for a 75 kDa protein.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Concanavalin A; Enzyme Activation; Genistein; Humans; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Tyrosine | 1994 |
Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human platelets.
Topics: Blood Platelets; Calcium; Dose-Response Relationship, Drug; Epoprostenol; Genistein; Humans; Intracellular Membranes; Isoflavones; Lipoproteins; Osmolar Concentration; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein-Tyrosine Kinases; Receptors, Epoprostenol; Receptors, Prostaglandin; Serotonin; Tyrosine | 1994 |
Listeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells.
Topics: Adhesins, Bacterial; Bacterial Adhesion; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cytochalasin D; Enzyme Activation; Epithelial Cells; Escherichia coli; Genistein; HeLa Cells; Humans; Isoflavones; Listeria monocytogenes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Yersinia enterocolitica | 1994 |
Vascular endothelial growth factor induces the disorganization of actin stress fibers accompanied by protein tyrosine phosphorylation and morphological change in Balb/C3T3 cells.
Topics: 3T3 Cells; Actins; Animals; Baculoviridae; Binding Sites; Cells, Cultured; Endothelial Growth Factors; Genistein; Isoflavones; Lymphokines; Mice; Mice, Inbred BALB C; Moths; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1994 |
The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes.
Topics: Benzoquinones; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Genes, Immediate-Early; Genistein; Humans; Integrins; Interleukin-1; Isoflavones; Lactams, Macrocyclic; Monocytes; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Transcriptional Activation; Tyrosine | 1994 |
Distinct protein tyrosine phosphorylation during mitogenesis induced in quiescent SV40-transformed 3T3 T cells by insulin or vanadate.
Topics: 3T3 Cells; Animals; Blotting, Western; Cell Line, Transformed; Genistein; Insulin; Isoflavones; Mice; Mitogens; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein-Tyrosine Kinases; Receptor, Insulin; Simian virus 40; T-Lymphocytes; Tyrosine; Vanadates | 1994 |
Glycosome-associated tyrosine-phosphorylated protein in Trypanosoma brucei.
Topics: Animals; Dose-Response Relationship, Drug; Genistein; Glycolysis; Immunohistochemistry; Isoflavones; Microscopy, Immunoelectron; Molecular Weight; Organelles; Phosphorylation; Protein-Tyrosine Kinases; Protozoan Proteins; Trypanosoma brucei brucei; Tyrosine | 1993 |
Brush-border tyrosine phosphorylation stimulates ileal neutral NaCl absorption and brush-border Na(+)-H+ exchange.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Calcimycin; Epidermal Growth Factor; Genistein; Ileum; Intestinal Absorption; Isoflavones; Male; Microvilli; Phosphorylation; Protein-Tyrosine Kinases; Rabbits; Serous Membrane; Sodium Chloride; Sodium-Hydrogen Exchangers; Tyrosine | 1994 |
Platelet-derived growth factor (PDGF) induction of egr-1 is independent of PDGF receptor autophosphorylation on tyrosine.
Topics: 3T3 Cells; Animals; Base Sequence; Calcium; CHO Cells; Cricetinae; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, Immediate-Early; Genes, mos; Genes, ras; Genistein; Immediate-Early Proteins; Isoflavones; Mice; Molecular Sequence Data; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Type C Phospholipases; Tyrosine | 1994 |
Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils: no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways.
Topics: Concanavalin A; Genistein; Humans; Hydroquinones; Ionomycin; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1993 |
Inhibitors of tyrosine phosphorylation induce apoptosis in human leukemic cell lines.
Topics: Apoptosis; Catechols; Cell Cycle; Cell Division; Flow Cytometry; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Isoflavones; Leukemia, Megakaryoblastic, Acute; Leukemia, Promyelocytic, Acute; Nitriles; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vanadates | 1993 |
Tyrosine kinase inhibitors impair fibroblast growth factor signaling in coronary endothelial cells.
Topics: Animals; Cattle; Cell Line; Cell Nucleus; Cinnamates; Coronary Vessels; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibroblast Growth Factors; Genistein; Isoflavones; Kinetics; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine | 1994 |
Requirement for tyrosine phosphorylation in lipopolysaccharide-induced murine B-cell proliferation.
Topics: Animals; B-Lymphocytes; Benzoquinones; Cell Division; Cells, Cultured; Genistein; Isoflavones; Lactams, Macrocyclic; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine | 1993 |
Inhibition of tyrosine phosphorylation prevents delayed neuronal death following cerebral ischemia.
Topics: Animals; Brain Ischemia; Calcium-Calmodulin-Dependent Protein Kinases; Cell Survival; Genistein; Gerbillinae; Hippocampus; Isoflavones; Male; Neurons; Phenols; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Time Factors; Tyrosine | 1993 |
Modulation of gastric mucosal calcium channel activity by mucus glycoprotein.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Epidermal Growth Factor; Gastric Mucosa; Genistein; Glycoproteins; Humans; In Vitro Techniques; Isoflavones; Male; Mucus; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine | 1993 |
Inhibition of herpes simplex virus replication by genistein, an inhibitor of protein-tyrosine kinase.
Topics: Animals; Cell Compartmentation; Fluorescent Antibody Technique; Genistein; Isoflavones; Phosphorylation; Protein-Tyrosine Kinases; Simplexvirus; Tyrosine; Vero Cells; Viral Envelope Proteins; Viral Plaque Assay; Virus Replication | 1993 |
Phospholipase C activation in the cytotoxic response of human natural killer cells requires protein-tyrosine kinase activity.
Topics: Benzoquinones; Cell Line; Cytotoxicity, Immunologic; Enzyme Activation; Genistein; Humans; Isoflavones; Killer Cells, Natural; Lactams, Macrocyclic; Phospholipases; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine | 1993 |
Genistein exhibits preferential cytotoxicity to a leukemogenic variant but induces differentiation of a non-leukemogenic variant of the mouse monocytic leukemia Mm cell line.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzoquinones; Cell Differentiation; Cell Division; Drug Screening Assays, Antitumor; Genistein; Isoflavones; Lactams, Macrocyclic; Leukemia, Monocytic, Acute; Mice; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tumor Cells, Cultured; Tyrosine | 1993 |
The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets.
Topics: Biological Transport; Blood Platelets; Blotting, Western; Calcium; Cells, Cultured; Cinnamates; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Indoles; Isoflavones; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Thrombin; Tyrosine | 1993 |
Regulation of eicosanoid biosynthesis in the macrophage. Involvement of protein tyrosine phosphorylation and modulation by selective protein tyrosine kinase inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Ascitic Fluid; Dinoprostone; Eicosanoids; Genistein; Isoflavones; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Nitriles; Phospholipases A; Phospholipases A2; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; SRS-A; Tyrosine; Tyrphostins; Zymosan | 1993 |
In vitro activation of the transcription factor ISGF3 by interferon alpha involves a membrane-associated tyrosine phosphatase and tyrosine kinase.
Topics: Base Sequence; Cell Membrane; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Genistein; HeLa Cells; Humans; Interferon-alpha; Interferon-Stimulated Gene Factor 3; Interferon-Stimulated Gene Factor 3, alpha Subunit; Interferon-Stimulated Gene Factor 3, gamma Subunit; Isoflavones; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Transcription Factors; Tyrosine | 1993 |
Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation.
Topics: Anticarcinogenic Agents; Catechols; Cell Division; Epidermal Growth Factor; ErbB Receptors; Estrogens, Non-Steroidal; Genistein; Humans; Isoflavones; Male; Nitriles; Phosphorylation; Prostatic Neoplasms; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1993 |
Protein tyrosine phosphorylation induced by epidermal growth factor and insulin-like growth factor-I in a rat clonal dental pulp-cell line.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Dental Pulp; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Isoflavones; Mice; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Tyrosine phosphorylation, MAPK and PLD in AII stimulated mitogenesis.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Genistein; Isoflavones; Mitosis; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligopeptides; Phospholipase D; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substrate Specificity; Tyrosine | 1995 |
Effect of genistein on amylase release and protein tyrosine phosphorylation in parotid acinar cells.
Topics: Amylases; Animals; Bucladesine; Carbachol; Cyclic AMP; Enzyme Inhibitors; Exocytosis; Genistein; Isoflavones; Isoproterenol; Parotid Gland; Phosphorylation; Protein-Tyrosine Kinases; Rats; Thionucleotides; Tyrosine | 1996 |
Coupling between [arginine8]-vasopressin-activated increases in protein tyrosine phosphorylation and cellular calcium in A7r5 aortic smooth muscle cells.
Topics: Animals; Arginine Vasopressin; Calcium; Cell Line; Enzyme Inhibitors; Extracellular Space; Genistein; Intracellular Fluid; Ion Transport; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Tyrosine; Vanadates | 1996 |
Protein tyrosine kinases regulate agonist-stimulated prostacyclin release but not von Willebrand factor secretion from human umbilical vein endothelial cells.
Topics: Calcium; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Exocytosis; Genistein; Guanosine Monophosphate; Histamine; Humans; Ionomycin; Ionophores; Isoflavones; Phosphorylation; Protein-Tyrosine Kinases; Styrenes; Thrombin; Tyrosine; von Willebrand Factor | 1996 |
Cell cycle progression proteins (cyclins), oncogene expression, and signal transduction during the proliferative response of human hepatocytes to hepatocyte growth factor.
Topics: Aged; Calcium; Cell Cycle; Cells, Cultured; Cyclic AMP; Cyclins; DNA; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression; Genistein; Hepatocyte Growth Factor; Humans; Inositol 1,4,5-Trisphosphate; Isoflavones; Liver; Male; Middle Aged; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Signal Transduction; Tyrosine | 1996 |
Extracellular ATP activates mast cells via a mechanism that is different from the activation induced by the cross-linking of Fc receptors.
Topics: Adenosine Triphosphate; Animals; beta-N-Acetylhexosaminidases; Calcium; Cell Line; Cross-Linking Reagents; Extracellular Space; Genistein; Histamine Release; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Isoflavones; Mast Cells; Mice; Mice, Inbred A; Mice, Inbred C57BL; Naphthalenes; Phosphorylation; Protein Kinase C; Receptors, Fc; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine | 1996 |
Involvement of tyrosine phosphorylation in the regulation of 5'-deiodinases in FRTL-5 rat thyroid cells and rat astrocytes.
Topics: Animals; Astrocytes; Bucladesine; Cell Line; Colforsin; Drug Combinations; Enzyme Inhibitors; Gene Expression; Genistein; Hydrocortisone; Iodide Peroxidase; Isoenzymes; Isoflavones; Phosphorylation; Rats; RNA, Messenger; Thyroid Gland; Thyrotropin; Tyrosine | 1996 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by genistein, a tyrosine kinase inhibitor.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Survival; Enzyme Inhibitors; Genistein; Haplorhini; Isoflavones; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine | 1996 |
Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells.
Topics: Butyrates; Butyric Acid; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Phosphorylation; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1996 |
Effect of cystathionine and cystathionine metabolites on the phosphorylation of tyrosine residues in human neutrophils.
Topics: Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; Isoflavones; Lactams, Macrocyclic; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Superoxides; Thiazepines; Tyrosine | 1996 |
Pervanadate mediated an increased generation of inositol phosphates and tension in rat myometrium. Activation and phosphorylation of phospholipase C-gamma 1.
Topics: Animals; Blotting, Western; Enzyme Inhibitors; Female; Genistein; Inositol Phosphates; Isoenzymes; Isoflavones; Myometrium; Nitriles; Phenols; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Type C Phospholipases; Tyrosine; Tyrphostins; Uterine Contraction; Vanadates | 1996 |
[Effect of specific activation of phosphatidylcholine metabolism in hamster fibroblasts transformed by Rous sarcoma virus].
Topics: Animals; Avian Sarcoma Viruses; Cell Line, Transformed; Cricetinae; Dexamethasone; Enzyme Inhibitors; Fibroblasts; Genistein; Isoflavones; Mesocricetus; Oncogene Protein pp60(v-src); Phosphatidylcholines; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine | 1996 |
Inhibition of tyrosine phosphorylation attenuates amino acid neurotransmitter release from the ischemic/reperfused rat cerebral cortex.
Topics: Amino Acids; Animals; Brain Ischemia; Enzyme Inhibitors; Genistein; Isoflavones; Male; Neurotransmitter Agents; Phosphorylation; Rats; Rats, Sprague-Dawley; Reperfusion; Tyrosine | 1996 |
Erythropoietin stimulates tyrosine phosphorylation and taurine transport in skate erythrocytes.
Topics: Animals; Anion Exchange Protein 1, Erythrocyte; Biological Transport; Enzyme Activation; Erythrocytes; Erythropoietin; Genistein; Hydrolysis; Isoenzymes; Isoflavones; Phosphatidylinositols; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Skates, Fish; Taurine; Type C Phospholipases; Tyrosine | 1996 |
Vanadate causes synthesis of endothelium-derived NO via pertussis toxin-sensitive G protein in pigs.
Topics: Animals; Arginine; Blood Vessels; Bradykinin; Cinnamates; Endothelium, Vascular; Genistein; GTP-Binding Proteins; Immunoblotting; Isoflavones; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pertussis Toxin; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sulfides; Swine; Tyrosine; Vanadates; Vasodilation; Virulence Factors, Bordetella | 1996 |
Protein tyrosine phosphorylation and the regulation of KCl cotransport in trout erythrocytes.
Topics: Animals; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Genistein; Isoflavones; Isoproterenol; K Cl- Cotransporters; Marine Toxins; Oncorhynchus mykiss; Oxazoles; Phosphorylation; Potassium Chloride; Protein-Tyrosine Kinases; Staurosporine; Symporters; Tyrosine; Vanadates | 1996 |
Calcium entry activated by store depletion in coronary endothelium is promoted by tyrosine phosphorylation.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Electric Conductivity; Endothelium, Vascular; Genistein; Hydroquinones; Isoflavones; Phosphorylation; Substance P; Swine; Tyrosine | 1996 |
Tyrosine kinases are required for catecholamine secretion and mitogen-activated protein kinase activation in bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Cattle; Cells, Cultured; Chromaffin System; Enzyme Activation; Genistein; Isoflavones; Mitogen-Activated Protein Kinase 1; Nicotine; Nitriles; Norepinephrine; Phosphorylation; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine; Tyrphostins | 1996 |
Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strain.
Topics: Animals; Aorta; Cattle; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Isoflavones; Nitriles; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Stress, Mechanical; Tissue Distribution; Tyrosine; Tyrphostins | 1996 |
Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha.
Topics: Alkaloids; Base Sequence; Calcimycin; Cell Hypoxia; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; I-kappa B Proteins; Ionophores; Isoflavones; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Kinase C; Protein Tyrosine Phosphatases; src-Family Kinases; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Endothelin-1 induces tyrosine phosphorylation in human blood monocytes.
Topics: Adult; Antibodies, Blocking; Benzoquinones; Blotting, Western; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Female; Genistein; Humans; In Vitro Techniques; Isoflavones; Janus Kinase 1; Lactams, Macrocyclic; Male; Monocytes; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Quinones; Receptors, Endothelin; Rifabutin; src-Family Kinases; Time Factors; Tyrosine | 1996 |
Effects of mitogens on androgen receptor-mediated transactivation.
Topics: Animals; Cell Line; COS Cells; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; HeLa Cells; Insulin-Like Growth Factor I; Intracellular Membranes; Isoflavones; Ligands; Mitogens; Phosphorylation; Phosphotyrosine; Rats; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Tyrosine; Vanadates | 1996 |
Rapid activation of mitogen-activated protein kinase and p21ras by prolactin and interleukin 2 in rat Nb2 node lymphoma cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Activation; Enzyme Inhibitors; Genistein; Guanosine Triphosphate; Interleukin-2; Isoflavones; Lymph Nodes; Lymphoma, T-Cell; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Porphyromonas gingivalis surface components induce interleukin-1 release and tyrosine phosphorylation in macrophages.
Topics: Animals; Bacterial Outer Membrane Proteins; Bacterial Proteins; Benzoquinones; Enzyme Inhibitors; Female; Fimbriae Proteins; Genistein; Interleukin-1; Isoflavones; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Phosphorylation; Porphyromonas gingivalis; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine | 1996 |
Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2).
Topics: Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; DNA; Enzyme Activation; Genistein; Glycoproteins; Humans; Hydroquinones; Isoflavones; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Osteosarcoma; Phosphorylation; Protease Inhibitors; Protein-Tyrosine Kinases; Proteins; Quinones; Rifabutin; Signal Transduction; Thymidine; Time Factors; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tritium; Tumor Cells, Cultured; Tyrosine | 1996 |
Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells.
Topics: Actins; Adrenal Cortex Neoplasms; Animals; Cell Adhesion Molecules; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Cytoskeleton; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Isoflavones; Mice; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1996 |
Cellular events concurrent with Porphyromonas gingivalis invasion of oral epithelium in vitro.
Topics: Cadaverine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Coated Pits, Cell-Membrane; Colchicine; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Epithelium; Genistein; Humans; Isoflavones; KB Cells; Microtubules; Nasopharynx; Nocodazole; Ouabain; Phosphorylation; Porphyromonas gingivalis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Staurosporine; Tyrosine | 1996 |
Involvement of microtubules in the control of adhesion-dependent signal transduction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Actin Cytoskeleton; Alkaloids; Animals; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; DNA; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Indoles; Integrins; Isoflavones; Mice; Microtubules; Myosin-Light-Chain Kinase; Nocodazole; Paclitaxel; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine; Vinblastine | 1996 |
Tyrosine phosphorylation of the dense plaque protein paxillin is regulated during smooth muscle contraction.
Topics: Acetylcholine; Analysis of Variance; Animals; Blotting, Western; Cytoskeletal Proteins; Dogs; Genistein; In Vitro Techniques; Isoflavones; Isometric Contraction; Kinetics; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Serotonin; Trachea; Tyrosine | 1996 |
Infection of human T lymphoid cells by human herpesvirus 6 is blocked by two unrelated protein tyrosine kinase inhibitors, biochanin A and herbimycin.
Topics: Benzoquinones; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Genistein; Herpesvirus 6, Human; Humans; Isoflavones; Lactams, Macrocyclic; Leukocytes, Mononuclear; Lymphocytes; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; T-Lymphocytes; Tyrosine | 1996 |
Effect of lipopolysaccharide on mitogen-activated protein kinases and cytosolic phospholipase A2.
Topics: Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Immunoblotting; Isoflavones; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Weight; Myelin Basic Protein; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Tyrosine | 1995 |
IL-2 and IL-4 mediate through two distinct kinase pathways for the activation of alphaCD3-induced activated killer cells.
Topics: Animals; CD3 Complex; Cytotoxicity, Immunologic; Enzyme Inhibitors; Female; Genistein; Immunophenotyping; Interleukin-1; Interleukin-4; Isoflavones; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1996 |
Correlation between cytosolic Ca2+ concentration, protein phosphorylation and platelet secretion.
Topics: Blood Platelets; Blood Proteins; Calcium; Calcium Chloride; Cytosol; Enzyme Inhibitors; Genistein; Humans; Ionomycin; Ionophores; Isoflavones; Myosin Light Chains; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Serotonin; Tyrosine | 1996 |
Translocation of phospholipase C-gamma 2 induced by in vitro activation of protein tyrosine kinase activity in mast cell lysates.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cations, Divalent; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Genistein; Isoenzymes; Isoflavones; Leukemia, Basophilic, Acute; Magnesium; Manganese; Mast Cells; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Sonication; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1996 |
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
Topics: Amyloid beta-Protein Precursor; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Isoflavones; Kidney; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tyrosine | 1996 |
The vav proto-oncogene product (p95vav) interacts with the Tyk-2 protein tyrosine kinase.
Topics: Benzoquinones; Cell Cycle Proteins; Enzyme Inhibitors; Genistein; Humans; Interferon-alpha; Isoflavones; Lactams, Macrocyclic; Multiple Myeloma; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Quinones; Rifabutin; Staurosporine; Tumor Cells, Cultured; TYK2 Kinase; Tyrosine | 1997 |
Tyrphostin 23 blocks phosphorylation of p42 but not p38 mitogen-activated protein kinase by zooxanthellatoxin-A.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Enzyme Inhibitors; Genistein; In Vitro Techniques; Indomethacin; Isoflavones; Male; Marine Toxins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Aggregation; Polyenes; Precipitin Tests; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Tyrphostins | 1997 |
Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation.
Topics: Animals; Calcium; Decapodiformes; Enzyme Inhibitors; Genistein; Isoflavones; Membrane Potentials; Microinjections; Patch-Clamp Techniques; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Stellate Ganglion; Synapses; Synaptic Transmission; Tyrosine; Vanadates | 1997 |
Human serotonin transporter: regulation by the neuroprotective agent aurintricarboxylic acid and by epidermal growth factor.
Topics: Aurintricarboxylic Acid; Biological Transport; Blotting, Northern; Carrier Proteins; Choriocarcinoma; Epidermal Growth Factor; Gene Expression; Genistein; Growth Inhibitors; Humans; Isoflavones; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuroprotective Agents; Phosphorylation; Placenta; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Tumor Cells, Cultured; Tyrosine | 1997 |
Tyrosine phosphorylation and Syk activation are involved in thrombin-induced aggregation of epinephrine-potentiated platelets.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Platelets; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Epinephrine; Epoprostenol; Genistein; Humans; Intracellular Signaling Peptides and Proteins; Isoflavones; Phenoxybenzamine; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Syk Kinase; Thrombin; Tyrosine | 1997 |
VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Inhibitors; Fibronectins; Flavonoids; Genistein; Humans; Integrin alpha4beta1; Integrin beta1; Integrins; Isoflavones; NF-kappa B; Nuclear Proteins; Phosphorylation; Receptors, Lymphocyte Homing; Receptors, Very Late Antigen; Thromboplastin; Trans-Activators; Tyrosine; Viral Proteins; Zinc Fingers | 1997 |
Functional link between tyrosine phosphorylation and human serotonin transporter gene expression.
Topics: Benzoquinones; Carrier Proteins; Choriocarcinoma; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Membrane Glycoproteins; Membrane Transport Proteins; Neoplasm Proteins; Nerve Tissue Proteins; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Tumor Cells, Cultured; Tyrosine; Uterine Neoplasms | 1997 |
Genistein, a protein tyrosine kinase inhibitor, ameliorates retinal degeneration after ischemia-reperfusion injury in rat.
Topics: Animals; Enzyme Inhibitors; Eye Proteins; Genistein; Ischemia; Isoflavones; Male; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retina; Retinal Degeneration; Retinal Vessels; Tyrosine | 1997 |
Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR.
Topics: Alanine; Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Aurintricarboxylic Acid; Biological Transport; Carrier Proteins; Choriocarcinoma; Cloning, Molecular; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; HeLa Cells; Humans; Isoflavones; Leucine; Phosphorylation; Placenta; Tumor Cells, Cultured; Tyrosine; Uterine Neoplasms | 1997 |
Tyrosine phosphorylation is required for ehrlichial internalization and replication in P388D1 cells.
Topics: Animals; Benzoquinones; Ehrlichia; Genistein; Glutamine; Isoflavones; Lactams, Macrocyclic; Leukemia P388; Macrophages; Methionine; Mice; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tyrosine | 1997 |
Transcriptional regulation of Sertoli cell immediate early genes by interleukin-6 and interferon-gamma is mediated through phosphorylation of STAT-3 and STAT-1 proteins.
Topics: Animals; Antineoplastic Agents; DNA; DNA-Binding Proteins; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Genistein; Interferon-gamma; Interleukin-6; Isoflavones; Male; Models, Molecular; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA; Serine; Sertoli Cells; STAT1 Transcription Factor; STAT3 Transcription Factor; Threonine; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Tyrosine | 1997 |
Direct action of genistein on CFTR.
Topics: Adenosine Triphosphate; Animals; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Inhibitors; Female; Genistein; Homeostasis; Isoflavones; Oocytes; Phosphoric Monoester Hydrolases; Phosphorylation; Stimulation, Chemical; Tyrosine; Xenopus laevis | 1997 |
Involvement of phospholipase C-gamma2 in activation of mitogen-activated protein kinase and phospholipase A2 by zooxanthellatoxin-A in rabbit platelets.
Topics: Animals; Arachidonic Acid; Blood Platelets; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Genistein; Indomethacin; Isoflavones; Male; Naphthalenes; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phosphorylation; Polyenes; Rabbits; Staurosporine; Type C Phospholipases; Tyrosine | 1997 |
Tyrosine phosphorylation in contraction of opossum esophageal longitudinal muscle in response to SNP.
Topics: Animals; Benzylidene Compounds; Carbachol; Cyclic GMP; Enzyme Inhibitors; Genistein; Isoflavones; Isometric Contraction; Models, Biological; Muscle Relaxation; Muscle, Smooth; Nitriles; Nitroprusside; Opossums; Phosphorylation; Phosphotyrosine; Potassium Chloride; Protein-Tyrosine Kinases; Trachea; Tyrosine; Tyrphostins | 1997 |
Identification of a Gal/GalNAc lectin in the protozoan Hartmannella vermiformis as a potential receptor for attachment and invasion by the Legionnaires' disease bacterium.
Topics: Acetylgalactosamine; Animals; Bacterial Adhesion; Galactose; Genistein; Hartmannella; Isoflavones; Lectins; Legionella pneumophila; Molecular Weight; Phosphorylation; Protozoan Proteins; Tyrosine | 1997 |
Genistein sensitivity of calcium transport pathways in serotonin-activated vascular smooth muscle cells.
Topics: Animals; Aorta; Biological Transport; Caffeine; Calcium; Calcium Channel Blockers; Cell Line; Enzyme Inhibitors; Genistein; Immunohistochemistry; Ionomycin; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Rats; Serotonin; Thapsigargin; Tyrosine | 1997 |
Tyrosine phosphorylation mediates ConA-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in MDA-MB-231 human breast carcinoma cells.
Topics: Concanavalin A; Enzyme Activation; Enzyme Inhibitors; Gelatinases; Genistein; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Neoplasm Proteins; Phosphorylation; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine; Up-Regulation | 1997 |
Protein tyrosine kinase activation provides an early and obligatory signal in anti-FRP-1/CD98/4F2 monoclonal antibody induced cell fusion mediated by HIV gp160.
Topics: Antibodies, Monoclonal; Antigens, CD; Benzoquinones; Carrier Proteins; Cell Fusion; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fusion Regulatory Protein-1; Genes, Viral; Genistein; HIV Envelope Protein gp160; Humans; Lactams, Macrocyclic; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Transfection; Tyrosine | 1997 |
Epiregulin stimulates proliferation of rabbit gastric cells in primary culture through autophosphorylation of the epidermal growth factor receptor.
Topics: Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Gastric Mucosa; Genistein; Phosphorylation; Protein-Tyrosine Kinases; Rabbits; Tyrosine | 1997 |
Lipopolysaccharide and pneumococcal cell wall components activate the mitogen activated protein kinases (MAPK) erk-1, erk-2, and p38 in astrocytes.
Topics: Animals; Astrocytes; Astrocytoma; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Wall; Cerebellar Cortex; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Streptococcus pneumoniae; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 1998 |
The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway.
Topics: Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Squamous Cell; Enzyme Activation; Enzyme Induction; Genistein; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Phosphotyrosine; Protein Kinase C; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1998 |
Protein tyrosine phosphorylation and calcium signaling in thyroid FRTL-5 cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; Genistein; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
Lipopolysaccharide protects polymorphonuclear leukocytes from apoptosis via tyrosine phosphorylation-dependent signal transduction pathways.
Topics: Apoptosis; Benzoquinones; Cell Survival; DNA Fragmentation; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; Lactams, Macrocyclic; Lipopolysaccharides; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Respiratory Burst; Rifabutin; Signal Transduction; Tyrosine | 1998 |
Leishmania amazonensis: the phagocytosis of amastigotes by macrophages.
Topics: Actins; Animals; Antimetabolites; Blotting, Western; Cytochalasin B; Cytoskeletal Proteins; Deoxyglucose; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Genistein; Humans; Leishmania mexicana; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Paxillin; Phagocytosis; Phosphoproteins; Phosphorylation; Talin; Tyrosine | 1998 |
Effect of tyrosine kinase inhibition on surfactant protein A gene expression during human lung development.
Topics: Embryonic and Fetal Development; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Genistein; Homeostasis; Humans; Lung; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Quinazolines; RNA, Messenger; Tyrosine; Tyrphostins | 1998 |
Effects of modulation of tyrosine phosphorylation on brush border enzyme activity in human Caco-2 intestinal epithelial cells.
Topics: Alkaline Phosphatase; Caco-2 Cells; Catechols; Cell Differentiation; Cell Division; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Hydroquinones; Microvilli; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Second Messenger Systems; Tyrosine; Tyrphostins; Vanadates | 1998 |
EGF-dependent and independent programmed cell death pathways in NCI-H596 nonsmall cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Non-Small-Cell Lung; Cell Division; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1998 |
Enhanced expression of Fas ligand is associated with aburatubolactam C-induced apoptosis in human Jurkat T cells.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoptosis; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Genistein; Humans; Jurkat Cells; Lactams; Membrane Glycoproteins; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; T-Lymphocytes; Tyrosine; Up-Regulation | 1998 |
Convulxin induces platelet activation by a tyrosine-kinase-dependent pathway and stimulates tyrosine phosphorylation of platelet proteins, including PLC gamma 2, independently of integrin alpha IIb beta 3.
Topics: Animals; Crotalid Venoms; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Lectins, C-Type; Phospholipase C gamma; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Solutions; Staurosporine; Type C Phospholipases; Tyrosine | 1998 |
Differential tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase F(A)/GSK-3alpha in well and poorly differentiated human prostate carcinoma cells.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Genistein; Glycogen Synthase Kinase 3; Humans; Male; Molecular Sequence Data; Oncogenes; Phosphorylation; Prostatic Neoplasms; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
1alpha,25(OH)2-vitamin D3 signaling in chick enterocytes: enhancement of tyrosine phosphorylation and rapid stimulation of mitogen-activated protein (MAP) kinase.
Topics: Animals; Calcitriol; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chickens; Duodenum; Enzyme Activation; Enzyme Inhibitors; Genistein; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Trypanosoma cruzi 175-kDa protein tyrosine phosphorylation is associated with host cell invasion.
Topics: Animals; Cell Extracts; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; HeLa Cells; Humans; Mice; Phosphorylation; Protein-Tyrosine Kinases; Protozoan Proteins; Rats; Signal Transduction; Trypanosoma cruzi; Tumor Cells, Cultured; Tyrosine | 1998 |
The association of platelet-derived growth factor (PDGF) receptor tyrosine phosphorylation to mitogenic response of human osteoblastic cells in vitro.
Topics: Becaplermin; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Humans; Immunoblotting; Maxilla; Osteoblasts; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Tyrosine | 1997 |
Lanthionine ketimine and S-(2-aminoethyl)-L-cysteine ketimine induce the tyrosyl phosphorylation of 45 kDa protein in parallel with its stimulation of superoxide generation in human neutrophils.
Topics: Amino Acids, Sulfur; Blood Proteins; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH Dehydrogenase; Neutrophils; Phosphorylation; Stimulation, Chemical; Superoxides; Tyrosine | 1997 |
Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor.
Topics: Animals; Biological Transport; Cell Line; Cytoplasm; Dimerization; Dogs; Endocytosis; Enzyme Activation; Genistein; Immunoglobulin A; Inositol Phosphates; Isoenzymes; Kidney; Ligands; Peptide Fragments; Phospholipase C gamma; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Receptors, Polymeric Immunoglobulin; Sequence Deletion; Type C Phospholipases; Tyrosine | 1998 |
The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Adhesion Molecules; Cells, Cultured; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Paxillin; Phosphoproteins; Phosphorylation; Plasminogen Activators; Protein-Tyrosine Kinases; Proteins; Pyrazoles; Pyrimidines; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Retinoblastoma-Like Protein p130; src-Family Kinases; Tyrosine; Urokinase-Type Plasminogen Activator | 1998 |
Potentiation by thyroid hormone of human IFN-gamma-induced HLA-DR expression.
Topics: Biological Transport; Cell Nucleus; Dextrothyroxine; Diiodothyronines; Drug Synergism; Genistein; HeLa Cells; HLA-DR Antigens; Humans; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Thyroxine; Time Factors; Trans-Activators; Transcription Factors; Triiodothyronine; Triiodothyronine, Reverse; Tyrosine | 1998 |
Constitutive activation of delayed-rectifier potassium channels by a src family tyrosine kinase in Schwann cells.
Topics: Animals; Benzoquinones; Cell Division; Cells, Cultured; Delayed Rectifier Potassium Channels; Enzyme Inhibitors; Genistein; Ion Channel Gating; Lactams, Macrocyclic; Mice; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quinones; Recombinant Proteins; Rifabutin; Schwann Cells; Sciatic Nerve; Shab Potassium Channels; src-Family Kinases; Tyrosine | 1998 |
CXCR1 and CXCR2 are rapidly down-modulated by bacterial endotoxin through a unique agonist-independent, tyrosine kinase-dependent mechanism.
Topics: Antigens, CD; Benzoquinones; Down-Regulation; Enzyme Inhibitors; Enzyme Precursors; Genistein; GTP-Binding Proteins; Humans; Interleukin-1; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lactams, Macrocyclic; Lipopolysaccharides; Molecular Weight; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Receptors, Chemokine; Receptors, Interleukin; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Rifabutin; Signal Transduction; Syk Kinase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 1998 |
Genistein suppresses adhesion-induced protein tyrosine phosphorylation and invasion of B16-BL6 melanoma cells.
Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Division; Genistein; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 1998 |
Tyrosine-phosphorylation-dependent and rho-protein-mediated control of cellular phosphatidylinositol 4,5-bisphosphate levels.
Topics: ADP-Ribosylation Factors; Bacterial Proteins; Bacterial Toxins; Cell Line; Clostridioides difficile; Enzyme Activation; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Membrane Proteins; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphorylation; rhoB GTP-Binding Protein; Tyrosine; Tyrphostins; Vanadates | 1998 |
Are tyrosine phosphorylation of p125(FAK) and paxillin or the small GTP binding protein, rho, needed for CCK-stimulated pancreatic amylase secretion?
Topics: ADP Ribose Transferases; Amylases; Animals; Botulinum Toxins; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin D; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; GTP-Binding Proteins; Male; Pancreas; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Signal transduction in activation of human eosinophils: G protein-dependent and -independent pathways.
Topics: Asthma; Cell Degranulation; Enzyme Inhibitors; Eosinophils; Genistein; GTP-Binding Proteins; Humans; Immunoglobulin A, Secretory; In Vitro Techniques; Inositol Phosphates; Isoenzymes; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Type C Phospholipases; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
Suppression of adhesion-induced protein tyrosine phosphorylation decreases invasive and metastatic potentials of B16-BL6 melanoma cells by protein tyrosine kinase inhibitor genistein.
Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Melanoma, Experimental; Mice; Neoplasm Invasiveness; Phosphorylation; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine | 1997 |
Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Antigen-Antibody Complex; Benzoquinones; Catalase; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Hydrogen Peroxide; Kinetics; Lactams, Macrocyclic; Mice; Phospholipase D; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Quinones; Rats; Receptors, Platelet-Derived Growth Factor; Rifabutin; Tyrosine; Vanadates | 1998 |
Role of intracellular calcium ([Ca2+]i) and tyrosine phosphorylation in adhesion of cultured vascular smooth muscle cells to fibrinogen.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Adhesion; Cell Line; Cells, Cultured; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Genistein; Humans; Integrins; Intracellular Fluid; Muscle, Smooth, Vascular; Nickel; Oligopeptides; Phosphorylation; Protein-Tyrosine Kinases; Rats; Regression Analysis; Tyrosine | 1998 |
Stimulation of cis-diamminedichloroplatinum(II) accumulation by modulation of passive permeability with genistein: an altered response in accumulation-defective resistant cells.
Topics: Antineoplastic Agents; Cell Membrane Permeability; Cisplatin; Enzyme Inhibitors; Genistein; Humans; Mannitol; Phosphorylation; Pinocytosis; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine | 1996 |
Involvement of protein kinases and phosphatases in tyrosine phosphorylation of PKCdelta in rat parotid acinar cells exposed to secretory stimuli.
Topics: Animals; Carbachol; Carcinogens; Enzyme Inhibitors; Epithelial Cells; Genistein; Isoenzymes; Muscarinic Agonists; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Consensus Sequence; Epidermal Growth Factor; Genistein; Insulin; Membrane Potentials; Mutagenesis, Site-Directed; Nerve Growth Factors; Oocytes; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates; Xenopus laevis | 1998 |
Hepatocyte growth factor/scatter factor (HGF/SF) induces vascular permeability factor (VPF/VEGF) expression by cultured keratinocytes.
Topics: 5' Untranslated Regions; Cell Line; Cycloheximide; Endothelial Growth Factors; Fibroblasts; Gene Expression; Genistein; Growth Inhibitors; Hepatocyte Growth Factor; Humans; Keratinocytes; Lymphokines; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Tyrosine; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Tyrosine phosphorylation of syndecan-1 and -4 cytoplasmic domains in adherent B82 fibroblasts.
Topics: Amino Acid Sequence; Benzoquinones; Cell Adhesion; Cell Polarity; Cytoplasm; Fibroblasts; Genistein; Lactams, Macrocyclic; Membrane Glycoproteins; Molecular Sequence Data; Phosphorylation; Protein Kinase Inhibitors; Proteoglycans; Quinones; Rifabutin; src-Family Kinases; Staurosporine; Syndecan-2; Syndecan-4; Syndecans; Tyrosine | 1998 |
Concanavalin A modulates tyrosine phosphorylation and activation of a type II phosphatidylinositol 4-kinase in rat splenic lymphocytes.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Antibodies; Concanavalin A; Enzyme Activation; Enzyme Inhibitors; Genistein; Lymphocyte Activation; Lymphocytes; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Rabbits; Rats; Rats, Wistar; Spleen; Tyrosine | 1998 |
Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein- and rho protein-mediated Ca2+ sensitization of smooth muscle of rabbit mesenteric artery.
Topics: Adenosine Diphosphate; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcium; Carcinogens; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; rho GTP-Binding Proteins; Ribose; Staurosporine; Tyrosine; Tyrphostins; Vasoconstrictor Agents | 1998 |
Epidermal growth factor-induced heterologous desensitization of the luteinizing hormone/choriogonadotropin receptor in a cell-free membrane preparation is associated with the tyrosine phosphorylation of the epidermal growth factor receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell-Free System; Chorionic Gonadotropin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Membrane Proteins; Ovary; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Receptors, LH; Time Factors; Tyrosine; Virulence Factors, Bordetella | 1999 |
Role of tyrosine phosphorylation in thrombin-induced endothelial cell contraction and barrier function.
Topics: Animals; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Genistein; Isoenzymes; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Protein-Tyrosine Kinases; Thrombin; Tyrosine | 1998 |
Extracellular matrix regulates apoptosis in human neutrophils.
Topics: Apoptosis; Cell Adhesion; Extracellular Matrix; Fibronectins; Genistein; Humans; Neutrophils; Phosphoproteins; Phosphorylation; Polyhydroxyethyl Methacrylate; Time Factors; Tissue Distribution; Tumor Necrosis Factor-alpha; Tyrosine | 1999 |
D-cystathionine ketimine and L-cystathionine ketimine enhance superoxide generation by human neutrophils in a different manner.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; Lactams, Macrocyclic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serine; Staurosporine; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Rapid inactivation of NOS-I by lipopolysaccharide plus interferon-gamma-induced tyrosine phosphorylation.
Topics: Astrocytoma; Enzyme Induction; Genistein; Humans; Interferon-gamma; Lipopolysaccharides; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phosphorylation; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
Possible regulation of epidermal growth factor-receptor tyrosine autophosphorylation by calcium and G proteins in chemically permeabilized rat UMR106 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Carcinoma; Cell Membrane Permeability; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; GTP-Binding Proteins; Humans; Osteoblasts; Osteosarcoma; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
Tyrosine phosphorylation/dephosphorylation controls capping of Fcgamma receptor II in U937 cells.
Topics: Arsenicals; Bacterial Proteins; Benzoquinones; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Lactams, Macrocyclic; Microscopy, Fluorescence; Okadaic Acid; Phosphorylation; Quinones; Receptor Aggregation; Receptors, IgG; Rifabutin; Streptolysins; Temperature; Time Factors; Tyrosine; U937 Cells; Vanadates | 1999 |
A 58-kDa Shc protein is present in Xenopus eggs and is phosphorylated on tyrosine residues upon egg activation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Fertilization; Genistein; GRB2 Adaptor Protein; Ovum; Parthenogenesis; Phosphorylation; Protein Binding; Proteins; Tyrosine; Xenopus laevis | 1999 |
Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Antimetabolites; Antimycin A; Carrier Proteins; Cell Line; Cytoskeleton; Deoxyglucose; Detergents; Electric Impedance; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genistein; Kidney Tubules, Distal; Membrane Proteins; Occludin; Octoxynol; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Solubility; Tight Junctions; Tyrosine; Zonula Occludens Proteins; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein | 1999 |
L-type Ca2+ current in guinea pig ventricular myocytes treated with modulators of tyrosine phosphorylation.
Topics: Animals; Cadmium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Electrophysiology; Enzyme Inhibitors; Estrogens, Non-Steroidal; Genistein; Guinea Pigs; Isoflavones; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Tyrphostins; Vanadates | 1999 |
Signal transduction pathway regulating prostaglandin EP3 receptor-induced neurite retraction: requirement for two different tyrosine kinases.
Topics: Alprostadil; Animals; Blotting, Western; Cytoskeletal Proteins; Enzyme Inhibitors; Genistein; Neurites; Paxillin; PC12 Cells; Phosphoproteins; Phosphorylation; Precipitin Tests; Prostaglandins E, Synthetic; Protein-Tyrosine Kinases; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Recombinant Proteins; Signal Transduction; Tyrosine; Tyrphostins | 1999 |
CD45 modulation of CXCR1 and CXCR2 in human polymorphonuclear leukocytes.
Topics: Antibodies, Monoclonal; Antigens, CD; Benzoquinones; Cells, Cultured; Chemokine CCL2; Chemokine CCL4; Down-Regulation; Genistein; Humans; Interleukin-8; Lactams, Macrocyclic; Leukocyte Common Antigens; Macrophage Inflammatory Proteins; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Receptors, Chemokine; Receptors, Interleukin; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Rifabutin; Tyrosine | 1999 |
Dibutyryl cyclic AMP-induced process formation in astrocytes is associated with a decrease in tyrosine phosphorylation of focal adhesion kinase and paxillin.
Topics: Actins; Animals; Astrocytes; Bucladesine; Cell Adhesion; Cell Adhesion Molecules; Cytochalasin D; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine; Vinculin | 1999 |
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.
Topics: Arsenicals; Cell Nucleus; Copper; Diamide; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; Hydrogen Peroxide; Iron; Lymphocytes; Oxidative Stress; Phenanthrolines; Phosphorylation; Phosphotyrosine; Phytohemagglutinins; Protein Tyrosine Phosphatases; Reactive Oxygen Species; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1999 |
Influence of phosphotyrosine kinase inhibitors on adhesive properties of highly and poorly metastatic HT-29 colon carcinoma cells to collagen.
Topics: Benzoquinones; Cell Adhesion; Collagen; Genistein; HT29 Cells; Humans; Integrins; Lactams, Macrocyclic; Neoplasms; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Receptors, Vitronectin; Rifabutin; Tyrosine | 1999 |
4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition.
Topics: Aldehydes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cross-Linking Reagents; Enzyme Activation; ErbB Receptors; Genistein; Humans; Lipid Peroxidation; Oxidative Stress; Phosphoproteins; Phosphorylation; Quinazolines; Signal Transduction; Tyrosine; Tyrphostins | 1999 |
Phosphotyrosine of macrophage by low-density lipoproteins from hemodialysis patients.
Topics: Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Lipoproteins, LDL; Macrophages; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Renal Dialysis; Tyrosine | 1999 |
Significance of capacitative Ca2+ entry in the regulation of phosphatidylserine expression at the surface of stimulated cells.
Topics: Aged; B-Lymphocytes; Blood Coagulation Disorders; Calcimycin; Calcium Channels; Cell Membrane; Cell Transformation, Viral; Cells, Cultured; Enzyme Inhibitors; Female; Genistein; Humans; Lymphocyte Activation; Phosphatidylserines; Phospholipids; Phosphorylation; Protein-Tyrosine Kinases; Syndrome; Thapsigargin; Tyrosine | 1999 |
Angiotensin II stimulates collagen synthesis in human vascular smooth muscle cells. Involvement of the AT(1) receptor, transforming growth factor-beta, and tyrosine phosphorylation.
Topics: Angiotensin II; Collagen; Enzyme Inhibitors; Fibrinogen; Genistein; Humans; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transforming Growth Factor beta; Tyrosine; Tyrphostins | 1999 |
Insulin-induced stimulation of Na+,K(+)-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the alpha-subunit at Tyr-10.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Enzyme Activation; Genistein; Insulin; Insulin Antagonists; Kidney Tubules, Proximal; Male; Opossums; Ouabain; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Transfection; Tyrosine; Vanadates | 1999 |
Beta-catenin is a major tyrosine-phosphorylated protein during mouse oocyte maturation and preimplantation development.
Topics: Animals; beta Catenin; Cadherins; Cytoskeletal Proteins; Embryonic Development; Enzyme Inhibitors; Epitopes; Female; Genistein; Immunohistochemistry; Mice; Mice, Inbred Strains; Oocytes; Phosphorylation; Precipitin Tests; Pregnancy; Protein Conformation; Protein-Tyrosine Kinases; Trans-Activators; Tyrosine | 1999 |
G(s)alpha repression of adipogenesis via Syk.
Topics: 3T3 Cells; Adipose Tissue; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Genistein; GTP-Binding Protein alpha Subunits; Heterotrimeric GTP-Binding Proteins; Intracellular Signaling Peptides and Proteins; Mice; Phosphorylation; Protein-Tyrosine Kinases; Syk Kinase; Tyrosine | 1999 |
Differential induction of tumor necrosis factor alpha and manganese superoxide dismutase by endotoxin in human monocytes: role of protein tyrosine kinase, mitogen-activated protein kinase, and nuclear factor kappaB.
Topics: Benzoquinones; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genistein; Humans; Lactams, Macrocyclic; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Monocytes; NF-kappa B; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Adhesion and pollution particle-induced oxidant generation is neither necessary nor sufficient for cytokine induction in human alveolar macrophages.
Topics: Adolescent; Adult; Air Pollutants; Cell Adhesion; Enzyme Inhibitors; Genistein; Humans; Interleukin-8; Macrophages, Alveolar; NF-kappa B; Oxidants; Oxidative Stress; Phosphorylation; Tyrosine | 2000 |
RPTPmu and protein tyrosine phosphorylation regulate K(+) channel mRNA expression in adult cardiac myocytes.
Topics: Age Factors; Animals; Cell Communication; CHO Cells; Cricetinae; Down-Regulation; Enzyme Inhibitors; Estrogens, Non-Steroidal; Female; Gene Expression Regulation, Enzymologic; Genistein; Heart Ventricles; Ion Channel Gating; Isoflavones; Kv1.5 Potassium Channel; Muscle Fibers, Skeletal; Myocardium; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 8; RNA, Messenger; Shal Potassium Channels; Signal Transduction; Tyrosine | 2000 |
Tyrosine phosphorylation modulates arteriolar tone but is not fundamental to myogenic response.
Topics: Animals; Arterioles; Enzyme Inhibitors; Genistein; In Vitro Techniques; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Phosphoric Monoester Hydrolases; Phosphorylation; Pressure; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins; Vanadates; Vasoconstriction; Vasomotor System | 2000 |
Surfactant protein A regulates pulmonary surfactant secretion via activation of phosphatidylinositol 3-kinase in type II alveolar cells.
Topics: Animals; Benzoquinones; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Genistein; Insulin Receptor Substrate Proteins; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Morpholines; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteolipids; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Quinones; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Rifabutin; Tyrosine | 2000 |
Tyrosine phosphorylation modulates the osmosensitivity of volume-dependent taurine efflux from glial cells in the rat supraoptic nucleus.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuroglia; Osmolar Concentration; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; rho GTP-Binding Proteins; Supraoptic Nucleus; Taurine; Tyrosine | 2000 |
Cross-linking of CD4 induces cytoskeletal association of CD4 and p56lck.
Topics: CD4 Antigens; Cross-Linking Reagents; Cytoskeleton; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; Genistein; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphorylation; Protein Binding; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 2000 |
Hepatocyte growth factor promotes migration of human hepatocellular carcinoma via phosphatidylinositol 3-kinase.
Topics: Androstadienes; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Hepatocyte Growth Factor; Humans; Isoenzymes; Naphthalenes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-met; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Wortmannin | 1999 |
Intracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs.
Topics: 3T3 Cells; Alanine; Amino Acid Motifs; Animals; Carboxylic Acids; Cell Compartmentation; Cell Membrane; Dipeptides; Endosomes; Enzyme Inhibitors; Genistein; Glucose Transporter Type 4; Golgi Apparatus; Insulin; Intracellular Membranes; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Peptide Fragments; Peptides; Phenylalanine; Protein-Tyrosine Kinases; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Tyrosine | 2000 |
Tyrosine phosphorylation of a 34-kDa protein induced by cross-linking a novel glycosylphosphatidylinositol-anchored glycoprotein (GPI-80) on human neutrophils that may regulate their adherence and migration.
Topics: Amidohydrolases; Androstadienes; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Chelating Agents; Cross-Linking Reagents; Cytochalasin B; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Genistein; GPI-Linked Proteins; Humans; Hydrolases; Indoles; Mice; Mice, Inbred BALB C; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Signal Transduction; Time Factors; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel.
Topics: Amino Acid Sequence; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genistein; GTP-Binding Proteins; Indole Alkaloids; Indoles; Lysine; Models, Biological; Molecular Sequence Data; Mutation; Oocytes; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Precipitin Tests; Receptor, trkB; RNA, Messenger; Staurosporine; Tyrosine; Xenopus | 2000 |
Tyrosine kinase-dependent calcium signaling in airway smooth muscle cells.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Genistein; Inositol Phosphates; Isoenzymes; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Serotonin; Trachea; Type C Phospholipases; Tyrosine; Tyrphostins | 2000 |
Involvement of tyrosine phosphorylation in the positive inotropic effect produced by H(1)-receptors with histamine in guinea-pig left atrium.
Topics: Animals; Atrial Function; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genistein; Guinea Pigs; Heart Atria; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Isoflavones; Isoproterenol; Male; Myocardial Contraction; Phosphorylation; Protein-Tyrosine Kinases; Pyrilamine; Receptors, Histamine H1; Time Factors; Tyrosine; Tyrphostins | 2000 |
Signal transduction mediated by adhesion of human trabecular meshwork cells to extracellular matrix.
Topics: Adult; Cell Adhesion; Cells, Cultured; Child, Preschool; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibronectins; Fluorescent Antibody Technique, Indirect; Genistein; Humans; Infant; Middle Aged; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases; Polylysine; Precipitin Tests; Signal Transduction; Time Factors; Trabecular Meshwork; Tyrosine | 2000 |
Mechanical strain-induced proliferation and signaling in pulmonary epithelial H441 cells.
Topics: Cell Division; Enzyme Inhibitors; Genistein; Humans; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction; Stress, Mechanical; Transcription Factor AP-1; Tumor Cells, Cultured; Tyrosine | 2000 |
Involvement of tyrosine kinase in citrate-stimulated aldosterone production in bovine glomerulosa cells.
Topics: Aldosterone; Animals; Calcium Chloride; Cattle; Citric Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Mineralocorticoid Receptor Antagonists; Osmolar Concentration; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Zona Glomerulosa | 2000 |
Protein tyrosine phosphorylation induced by ubiquitin-like polypeptide in murine T helper clone type 2.
Topics: Animals; Antibodies; Benzoquinones; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Interferon-gamma; Interleukin-4; Lactams, Macrocyclic; Mice; Phosphorylation; Protein Isoforms; Protein-Tyrosine Kinases; Proteins; Quinones; Receptors, Cell Surface; Rifabutin; Signal Transduction; Suppressor Factors, Immunologic; Th2 Cells; Tyrosine | 2000 |
Oncostatin M stimulates the growth of dermal fibroblasts via a mitogen-activated protein kinase-dependent pathway.
Topics: Adult; Biological Transport; Cell Nucleus; Cells, Cultured; DNA; Enzyme Inhibitors; Fibroblasts; Genetic Vectors; Genistein; Growth Substances; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; Oncostatin M; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Skin; Transfection; Tyrosine | 2000 |
Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Carbachol; Genistein; Humans; Molsidomine; Neuroblastoma; Nitrates; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2000 |
Stimulation of the mitogen-activated protein kinase cascade and tyrosine phosphorylation of the epidermal growth factor receptor by hepatopoietin.
Topics: Enzyme Inhibitors; ErbB Receptors; Genistein; Hepatocyte Growth Factor; Humans; MAP Kinase Signaling System; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2000 |
Melatonin-induced organelle movement in melanophores is coupled to tyrosine phosphorylation of a high molecular weight protein.
Topics: Adenylate Cyclase Toxin; Animals; Blotting, Western; Cell Aggregation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Genistein; GTP-Binding Proteins; Kinetics; Melanophores; Melatonin; Pertussis Toxin; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Serine; Signal Transduction; Threonine; Time Factors; Tyrosine; Virulence Factors, Bordetella; Xenopus | 2000 |
DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; Cations; Chromatography, Agarose; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genistein; Guanosine Triphosphate; Humans; Magnesium; Manganese; Medulloblastoma; Mice; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Phosphates; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Threonine; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
Involvement of focal adhesion kinase in Escherichia coli invasion of human brain microvascular endothelial cells.
Topics: Brain; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Escherichia coli; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine | 2000 |
Cloning and functional expression of rKCNQ2 K(+) channel from rat brain.
Topics: Animals; Benzoquinones; Brain Chemistry; Cells, Cultured; Cloning, Molecular; Enzyme Inhibitors; Epilepsy; Gene Expression; Genistein; Humans; KCNQ2 Potassium Channel; Kidney; Lactams, Macrocyclic; Membrane Potentials; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; RNA, Messenger; Sequence Homology, Amino Acid; Tetraethylammonium; Tyrosine; Xenopus | 2000 |
H(2)O(2)-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells.
Topics: Animals; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Gene Expression; Genes, jun; Genistein; Hydrogen Peroxide; Immediate-Early Proteins; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Rats; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Transcription Factors; Tyrosine; Tyrphostins | 2000 |
Bombesin and gastrin releasing peptide increase tyrosine phosphorylation of focal adhesion kinase and paxillin in non-small cell lung cancer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bombesin; Carcinoma, Non-Small-Cell Lung; Cell Division; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastrin-Releasing Peptide; Genistein; Humans; Lung Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine | 2001 |
Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies.
Topics: Antibodies, Antineutrophil Cytoplasmic; Genistein; Humans; In Vitro Techniques; Kinetics; Mitogen-Activated Protein Kinases; Myeloblastin; Naphthalenes; Neutrophils; p38 Mitogen-Activated Protein Kinases; Peroxidase; Phosphorylation; Respiratory Burst; Serine Endopeptidases; Signal Transduction; Staurosporine; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Constitutive activation of Lck and Fyn tyrosine kinases in large granular lymphocytes infected with the gamma-herpesvirus agents of malignant catarrhal fever.
Topics: Animals; Cattle; Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Genistein; Herpesviridae; Immunophenotyping; Interleukin-2; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocyte Subsets; Malignant Catarrh; Mitogen-Activated Protein Kinase 1; Mitogens; Phosphoproteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Rabbits; T-Lymphocytes; Tyrosine | 2001 |
Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors.
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; CHO Cells; Cinnamates; Cricetinae; Enzyme Inhibitors; Flavonoids; Genistein; Glucose Transporter Type 1; Hexoses; HL-60 Cells; Humans; Isoflavones; meta-Aminobenzoates; Monosaccharide Transport Proteins; Phenols; Protein Binding; Protein-Tyrosine Kinases; Quercetin; Salicylates; Substrate Specificity; Tyrosine; Tyrphostins | 2001 |
Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen.
Topics: Age Factors; Animals; Blotting, Western; Cell Division; Cell Nucleus; Cells, Cultured; Cyclin B; Cyclin B1; Cyclin D1; Cytoplasm; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Female; Fibroblasts; Fulvestrant; Genistein; Hypoxia; Male; Myocardium; Phosphorylation; Precipitin Tests; Proliferating Cell Nuclear Antigen; Protein Binding; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Receptors, Estrogen; Response Elements; Sex Factors; Tyrosine | 2000 |
Tyrosine phosphorylation increases Ca2+ sensitivity of vascular smooth muscle contraction.
Topics: Animals; Calcium; Calcium Radioisotopes; Genistein; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phosphorylation; Potassium Chloride; Tyrosine; Vanadates; Vasoconstrictor Agents | 2000 |
Involvement of alpha5beta1 integrins in interleukin 8 production induced by oral viridans streptococcal protein I/IIf in cultured endothelial cells.
Topics: Adhesins, Bacterial; Animals; Apigenin; Bacterial Proteins; Benzoquinones; Cells, Cultured; CHO Cells; Cricetinae; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Guanosine Diphosphate; Humans; Immunoblotting; Integrins; Interleukin-8; Isoenzymes; Lactams, Macrocyclic; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Paxillin; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Quinones; Receptors, Vitronectin; Rifabutin; Streptococcus mutans; Thionucleotides; Type C Phospholipases; Tyrosine | 1999 |
Differences in TNF-alpha producing activity from murine peritoneal macrophages induced by lipopolysaccharides of Prevotella heparinolytica and Porphyromonas gingivalis.
Topics: Animals; Deoxycholic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genistein; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Phosphorylation; Porphyromonas gingivalis; Prevotella; Protein-Tyrosine Kinases; Salmonella; Sodium Dodecyl Sulfate; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
PTH stimulates PLCbeta and PLCgamma isoenzymes in rat enterocytes: influence of ageing.
Topics: Aging; Animals; Benzoquinones; Blotting, Western; Cells, Cultured; Duodenum; Electrophoresis, Polyacrylamide Gel; Enterocytes; Genistein; Inositol Phosphates; Isoenzymes; Lactams, Macrocyclic; Male; Parathyroid Hormone; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein Isoforms; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Rats, Wistar; Rifabutin; Subcellular Fractions; Time Factors; Type C Phospholipases; Tyrosine | 2001 |
Phospholipase C-gamma mediates the hydrolysis of phosphatidylinositol, but not of phosphatidylinositol 4,5-bisphoshate, in carbamylcholine-stimulated islets of langerhans.
Topics: Adenoviridae; Androstadienes; Animals; Carbachol; Cholinergic Agonists; Chromatography, High Pressure Liquid; Chromones; Enzyme Inhibitors; Genistein; Hydrolysis; Inositol Phosphates; Islets of Langerhans; Isoenzymes; Membrane Potentials; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Signal Transduction; Time Factors; Type C Phospholipases; Tyrosine; Vanadates; Wortmannin | 2001 |
Tyrosine kinase-dependent, phosphatidylinositol 3'-kinase, and mitogen-activated protein kinase-independent signaling pathways prevent lung adenocarcinoma cells from anoikis.
Topics: Adenocarcinoma; Anoikis; Cell Adhesion; Cell Survival; Enzyme Inhibitors; Genistein; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 2001 |
Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions.
Topics: Acetaldehyde; beta Catenin; Caco-2 Cells; Cadherins; Cytoskeletal Proteins; Enzyme Inhibitors; Epithelium; Genistein; Humans; Membrane Proteins; Permeability; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tight Junctions; Trans-Activators; Tyrosine; Zonula Occludens-1 Protein | 2001 |
The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
Topics: Androstadienes; Cell Division; Cell Line; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Genistein; Humans; Imidazoles; Immunoblotting; Interferon-alpha; Intracellular Signaling Peptides and Proteins; K562 Cells; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Tyrosine; Wortmannin | 2001 |
Actions of the soy phytoestrogen genistein in models of human chronic disease: potential involvement of transforming growth factor beta.
Topics: Animals; Brain; Cell Line; Chronic Disease; Clinical Trials as Topic; Culture Media, Conditioned; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Genistein; Glycine max; Humans; Macaca fascicularis; Phosphorylation; Postmenopause; Receptors, Estrogen; Signal Transduction; tau Proteins; Transforming Growth Factor beta; Tyrosine | 2001 |
Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor subunit 2B after cerebral ischemia/reperfusion.
Topics: Animals; Calcium Channel Blockers; Genistein; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Ketamine; Nifedipine; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Synaptosomes; Tyrosine; Vanadates | 2000 |
Immunotoxin FN18-CRM9 induces stronger T cell signaling than unconjugated monoclonal antibody FN18.
Topics: Amino Acid Motifs; Animals; Antibodies, Monoclonal; Biological Transport; CD3 Complex; Diphtheria Toxin; Down-Regulation; Enzyme Inhibitors; Genistein; Immunotoxins; Macaca mulatta; Male; Phosphorylation; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes; Tyrosine | 2001 |
Cellular mechanisms for amyloid beta-protein activation of rat cholinergic basal forebrain neurons.
Topics: Actins; Amyloid beta-Peptides; Animals; Calcium; Charybdotoxin; Choline O-Acetyltransferase; Delayed Rectifier Potassium Channels; Diagonal Band of Broca; Enzyme Inhibitors; Gene Expression; Genistein; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phenotype; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium; Tetraethylammonium; Tyrosine; Tyrphostins | 2001 |
Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation.
Topics: Animals; Binding Sites; Biotinylation; Carrier Proteins; Cell Membrane; CHO Cells; Cricetinae; GABA Plasma Membrane Transport Proteins; Genistein; Immunoblotting; Ligands; Membrane Proteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Mutation; Nipecotic Acids; Organic Anion Transporters; Phosphorylation; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Signal Transduction; Transfection; Tyrosine; Up-Regulation | 2001 |
Involvement of pp125FAK and p60SRC in the signaling through Fc gamma RII-Fc gamma RIII in murine macrophages.
Topics: Animals; Cell Line; Cross-Linking Reagents; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Ligands; Macrophages; Mice; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Receptors, IgG; Signal Transduction; Tyrosine | 2001 |
Involvement of MAPK activation in bacterial endotoxin-inducible tissue factor upregulation in human monocytic THP-1 cells.
Topics: Cell Line; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Genistein; Humans; Imidazoles; Isoenzymes; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Monocytes; Phosphorylation; Pyridines; Thromboplastin; Tyrosine; Up-Regulation | 2001 |
Preconditioning of 3T3 cells by fresh medium together with genistein enhances prostaglandin E(2) release.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Culture Media; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Genistein; Immunoblotting; Isoenzymes; Membrane Proteins; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Tyrosine | 2001 |
12-lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Cell Division; DNA; Enzyme Activation; Genistein; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2001 |
Genistein prevents nuclear factor-kappa B activation and acute lung injury induced by lipopolysaccharide.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokines, CXC; Chemotactic Factors; Escherichia coli; Genistein; Growth Inhibitors; Growth Substances; Intercellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Lipopolysaccharides; Lung; Macrophages, Alveolar; Male; Matrix Metalloproteinase 9; Neutrophils; NF-kappa B; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Transcriptional Activation; Tyrosine | 2001 |
The late-domain-containing protein p6 is the predominant phosphoprotein of human immunodeficiency virus type 1 particles.
Topics: Cell Line; Cyclin-Dependent Kinases; Endopeptidases; Enzyme Inhibitors; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Genistein; HIV-1; Humans; Kinetin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Purines; Serine; Threonine; Tyrosine; Virion | 2002 |
D609-sensitive tyrosine phosphorylation is involved in Fas-mediated phospholipase D activation.
Topics: Animals; Antibodies, Monoclonal; Bridged-Ring Compounds; Cell Line; Cross-Linking Reagents; Dose-Response Relationship, Immunologic; Enzyme Activation; fas Receptor; Genistein; Hydrolysis; Lymphoma; Mice; Norbornanes; Phospholipase D; Phosphorylation; Phosphorylcholine; Solubility; Thiocarbamates; Thiones; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Water | 2001 |
Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase.
Topics: Blotting, Western; Cell Line; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Humans; Models, Biological; Mutation; Nerve Tissue Proteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; Thrombin; Time Factors; Transfection; Tyrosine | 2002 |
Recycling ability of the mouse and the human neurotensin type 2 receptors depends on a single tyrosine residue.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Brefeldin A; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Genistein; Humans; Kinetics; Mice; Microscopy, Confocal; Molecular Sequence Data; Monensin; Neurotensin; Phosphorylation; Protein Structure, Secondary; Protein Synthesis Inhibitors; Protein Transport; Receptors, Neurotensin; Recombinant Fusion Proteins; Sequence Alignment; Tyrosine | 2002 |
Regulation of an ERG K+ current by Src tyrosine kinase.
Topics: Adenosine Triphosphate; Animals; Benzoquinones; Blotting, Western; Cation Transport Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Genistein; Humans; Kinetics; Lactams, Macrocyclic; Peptides; Phenols; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Precipitin Tests; Protein-Tyrosine Kinases; Quinones; Rats; Reverse Transcriptase Polymerase Chain Reaction; Rifabutin; Signal Transduction; src-Family Kinases; Time Factors; Trans-Activators; Transcriptional Regulator ERG; Transfection; Tyrosine | 2002 |
Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation.
Topics: Genistein; Humans; Isoflavones; Lipoproteins, LDL; Nitrates; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Tyrosine | 2002 |
Inhibitors of receptor tyrosine kinases do not suppress progesterone-induced [Ca2+]i signalling in human spermatozoa.
Topics: Acrosome; Blotting, Western; Calcium; Calcium Signaling; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; Male; Progesterone; Receptor Protein-Tyrosine Kinases; Signal Transduction; Spermatozoa; Tyrosine; Tyrphostins | 2002 |
Genistein inhibits CCAAT/enhancer-binding protein beta (C/EBPbeta) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression.
Topics: 3T3 Cells; Adipocytes; Animals; Anticarcinogenic Agents; Azo Compounds; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Line; Cell Nucleus; Coloring Agents; DNA; Enzyme Inhibitors; Genistein; Immunoblotting; Isoflavones; Lipid Metabolism; Mice; Phosphorylation; Precipitin Tests; Protein Binding; Receptors, Cytoplasmic and Nuclear; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tyrosine | 2002 |
Role of pp60(c-src) and p(44/42) MAPK in ANG II-induced contraction of rat tonic gastrointestinal smooth muscles.
Topics: Angiotensin II; Animals; Antibodies; Benzoquinones; Calmodulin-Binding Proteins; Digestive System; Digestive System Physiological Phenomena; Enzyme Inhibitors; Female; Flavonoids; Genistein; In Vitro Techniques; Lactams, Macrocyclic; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth; p120 GTPase Activating Protein; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Tyrosine | 2002 |
Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress.
Topics: beta Catenin; Caco-2 Cells; Cadherins; Cell Membrane; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Genistein; Humans; Intercellular Junctions; Membrane Proteins; Occludin; Oxidative Stress; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Trans-Activators; Tyrosine; Xanthine; Xanthine Oxidase; Zonula Occludens-1 Protein | 2002 |
Genistein treatment reduces arterial contractions by inhibiting tyrosine kinases in ovariectomized hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Body Weight; Creatinine; Eating; Electrolytes; Enzyme Inhibitors; Estradiol; Female; Genistein; Hypertension; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Ovariectomy; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Renal Circulation; Tyrosine; Uterus | 2002 |
Prostaglandin F(2alpha) stimulates tyrosine phosphorylation of phospholipase C-gamma1.
Topics: Animals; Blotting, Western; Cats; Cells, Cultured; Dinoprost; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Iris; Isoenzymes; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein Binding; Signal Transduction; Time Factors; Type C Phospholipases; Tyrosine; Tyrphostins | 2002 |
Activation of D2-like receptors causes recruitment of tyrosine-phosphorylated NKA alpha 1-subunits in kidney.
Topics: Animals; Anti-Bacterial Agents; Bromocriptine; Cell Membrane; Enzyme Inhibitors; Genistein; Isoenzymes; Kidney; Kidney Tubules, Proximal; Macrolides; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Sodium-Potassium-Exchanging ATPase; Tyrosine | 2002 |
Mitogenic activity of dermatofibrosarcoma protuberans is mediated via an extracellular signal related kinase dependent pathway.
Topics: Cell Division; Cell Nucleus; Dermatofibrosarcoma; DNA; Genistein; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine | 2002 |
Endocytosis of Candida albicans by vascular endothelial cells is associated with tyrosine phosphorylation of specific host cell proteins.
Topics: Bacterial Adhesion; Candida albicans; Cells, Cultured; Endocytosis; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Humans; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Tyrosine; Tyrphostins | 2002 |
Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
Topics: Arachidonic Acid; Blood Proteins; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Activation of the G(i) heterotrimeric G protein by ANCA IgG F(ab')2 fragments is necessary but not sufficient to stimulate the recruitment of those downstream mediators used by intact ANCA IgG.
Topics: Antibodies, Antineutrophil Cytoplasmic; Enzyme Inhibitors; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Neutrophils; Pertussis Toxin; Phosphatidylinositols; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; ras GTPase-Activating Proteins; Signal Transduction; Superoxides; Tyrosine | 2003 |
Serine 338 phosphorylation is dispensable for activation of c-Raf1.
Topics: Androstadienes; Blotting, Western; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genistein; Glutathione Transferase; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-raf; ras Proteins; Serine; Signal Transduction; Time Factors; Tyrosine; U937 Cells; Wortmannin | 2003 |
Delayed arteriolar relaxation after prolonged agonist exposure: functional remodeling involving tyrosine phosphorylation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arterioles; Calcium; Demecolcine; Enzyme Inhibitors; Flavonoids; Genistein; Male; Microtubules; Norepinephrine; Phosphorylation; Potassium Chloride; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine; Vasoconstrictor Agents; Vasodilation | 2003 |
Initial signaling of the fibronectin receptor (alpha5beta1 integrin) in hepatic stellate cells is independent of tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Extracellular Matrix; Genistein; Integrin alpha5beta1; Lactams, Macrocyclic; Ligands; Liver; Male; Microspheres; Phosphorylation; Polylysine; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Signal Transduction; Tyrosine | 2003 |
Ligand-independent tyrosine kinase signalling in RTH 149 trout hepatoma cells: comparison among heavy metals and pro-oxidants.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Copper; DNA-Binding Proteins; Dose-Response Relationship, Drug; Genistein; Hydrogen Peroxide; Imidazoles; Ligands; Mercury; Metals, Heavy; Milk Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Receptor Protein-Tyrosine Kinases; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Tyrosine | 2003 |
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2003 |
Molecular mechanism of adaptive cytoprotection induced by ethanol in human gastric cells.
Topics: Cell Line, Tumor; Culture Media; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytoprotection; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Genistein; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Processing, Post-Translational; Stomach; Time Factors; Tyrosine | 2003 |
Inhibitory effect of genistein on activation of STAT3 induced by brain ischemia/reperfusion in rat hippocampus.
Topics: Animals; Brain Ischemia; DNA-Binding Proteins; Genistein; Hippocampus; Male; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; STAT3 Transcription Factor; Trans-Activators; Tyrosine | 2003 |
Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Line; Cholesterol; Cricetinae; Enzyme Inhibitors; Fibrosarcoma; Genistein; Humans; Isoquinolines; Janus Kinase 2; Kidney; Mutation; Phospholipids; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Proteins; RNA, Messenger; Sulfonamides; Transfection; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2004 |
[Relationship between protein tyrosine phosphorylation level and anoikis resistance of breast tumor cell lines].
Topics: Animals; Anoikis; Breast Neoplasms; Cell Line, Tumor; Dogs; Female; Genistein; Humans; Phosphorylation; Tyrosine | 2004 |
mRNA is an endogenous ligand for Toll-like receptor 3.
Topics: Blotting, Northern; Cell Line; Dendritic Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genistein; Humans; Interleukin-1 Receptor-Associated Kinases; Interleukin-8; Ligands; Luciferases; Membrane Glycoproteins; Necrosis; NF-kappa B; Nucleic Acid Conformation; Plasmids; Protein Kinases; Receptors, Cell Surface; RNA; RNA, Double-Stranded; RNA, Messenger; Signal Transduction; Staurosporine; Toll-Like Receptor 3; Toll-Like Receptors; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2004 |
Receptor-operated Ca2+ influx and its association with the Src family in secretagogue-stimulated pancreatic acini.
Topics: Amylases; Animals; Calcium; Cattle; Cholecystokinin; Enzyme Inhibitors; Fibroblast Growth Factors; Genes, src; Genistein; Humans; Ionomycin; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Recombinant Proteins; Sodium Fluoride; Tyrosine | 2004 |
Growth hormone promotes Ca(2+)-induced Ca2+ release in insulin-secreting cells by ryanodine receptor tyrosine phosphorylation.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Diazoxide; Enzyme Inhibitors; Genistein; Growth Hormone; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Nifedipine; Phosphorylation; Potassium; Protein-Tyrosine Kinases; Rats; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Tyrosine | 2004 |
Infection with Campylobacter jejuni induces tyrosine-phosphorylated proteins into INT-407 cells.
Topics: Campylobacter jejuni; Cells, Cultured; Enzyme Inhibitors; Genistein; Humans; Intestines; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Staurosporine; Tyrosine; Tyrphostins | 2004 |
Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells.
Topics: Animals; Arsenicals; Cell Line; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Genistein; Glycine; Humans; N-Methylaspartate; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Resorcinols; Staurosporine; Thapsigargin; Transfection; Tyrosine; Vanadates | 2004 |
Differentiation of sulfate and phosphate by H/D exchange mass spectrometry: application to isoflavone.
Topics: Genistein; Isoflavones; Mass Spectrometry; Molecular Weight; Nitrophenols; Phosphates; Sulfates; Tyrosine | 2004 |
Signaling function of PSGL-1 in neutrophil: tyrosine-phosphorylation-dependent and c-Abl-involved alteration in the F-actin-based cytoskeleton.
Topics: Actins; Antibodies, Monoclonal; Antineoplastic Agents; Benzamides; Cross-Linking Reagents; Cytoskeleton; Genistein; Humans; Imatinib Mesylate; Membrane Glycoproteins; Neutrophils; Phosphorylation; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Pyrimidines; Signal Transduction; Tyrosine | 2005 |
Transcriptional regulation of the Grp78 promoter by endoplasmic reticulum stress: role of TFII-I and its tyrosine phosphorylation.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line; Chromatin Immunoprecipitation; CSK Tyrosine-Protein Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Genes, Reporter; Genistein; Heat-Shock Proteins; Humans; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; Models, Genetic; Molecular Chaperones; NIH 3T3 Cells; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Time Factors; Transcription Factors, TFII; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine | 2005 |
Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Anilides; Animals; Aorta, Thoracic; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Genistein; Hypertension; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; PPAR gamma; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Signal Transduction; Stroke; Superoxides; Tyrosine; Vasoconstrictor Agents | 2004 |
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses.
Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; beta Catenin; Blotting, Western; Brain; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Dendrites; Diagnostic Imaging; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Genistein; Green Fluorescent Proteins; Hippocampus; Humans; Immunohistochemistry; Immunoprecipitation; Membrane Potentials; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-myc; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; RNA, Antisense; RNA, Small Interfering; Synapses; Time Factors; Trans-Activators; Transfection; Tyrosine; Vanadates | 2005 |
Prolactin stimulates integrin-mediated adhesion of circulating mononuclear cells to endothelial cells.
Topics: Adult; Cell Adhesion; Dose-Response Relationship, Drug; Endothelium, Vascular; Genistein; Humans; Integrins; Jurkat Cells; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Prolactin; Receptors, Chemokine; Receptors, CXCR3; RNA, Messenger; Tyrosine; Up-Regulation | 2005 |
Revealing anti-inflammatory mechanisms of soy isoflavones by flow: modulation of leukocyte-endothelial cell interactions.
Topics: Anti-Inflammatory Agents; Aorta; Cell Adhesion; Cell Adhesion Molecules; Cell Communication; Cells, Cultured; Endothelial Cells; Genistein; Glycine max; Humans; Isoflavones; Leukocytes; Monocytes; Phosphorylation; PPAR gamma; Reactive Oxygen Species; Receptors, Estrogen; Stress, Mechanical; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Biotinylation; Blotting, Western; Bungarotoxins; Choline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Genistein; Hippocampus; Insulin; Interneurons; Iodine Isotopes; Ion Channel Gating; Membrane Potentials; Microinjections; Mutagenesis; N-Methylaspartate; Oocytes; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Radioligand Assay; Rats; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SNARE Proteins; Time Factors; Tyrosine; Up-Regulation; Vanadates; Xenopus | 2005 |
Constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in trans-Golgi.
Topics: Animals; Biomarkers; Cells, Cultured; Enzyme Inhibitors; Genistein; Hepatocytes; Male; Phosphoprotein Phosphatases; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Rats; Serum Albumin; Substrate Specificity; trans-Golgi Network; Tyrosine; Vanadates | 2005 |
Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoflurane; Male; Methyl Ethers; Muscle Contraction; Muscle, Smooth, Vascular; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Sevoflurane; Tyrosine; Vanadates | 2005 |
Involvement of BKCa alpha subunit tyrosine phosphorylation in vascular hyporesponsiveness of superior mesenteric artery following hemorrhagic shock in rats.
Topics: Animals; Genistein; Hypotension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Phosphorylation; Potassium Channels; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Shock, Hemorrhagic; Time Factors; Tyrosine; Vanadates; Vascular Resistance; Vasodilation | 2005 |
Shiga toxin regulates its entry in a Syk-dependent manner.
Topics: Clathrin Heavy Chains; Endocytosis; Enzyme Activation; Genistein; Golgi Apparatus; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Multiprotein Complexes; Phosphorylation; Protein Binding; Protein Transport; Protein-Tyrosine Kinases; Shiga Toxin; Stilbenes; Syk Kinase; Tyrosine | 2006 |
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro.
Topics: Animals; Calcium; Carbachol; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Estrenes; Genistein; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Rabbits; Tyrosine; Tyrphostins; Vanadates; Verapamil | 2006 |
Angiotensin II modulates tyr-phosphorylation of IRS-4, an insulin receptor substrate, in rat liver membranes.
Topics: Androstadienes; Angiotensin II; Animals; Cell Membrane; Genistein; Insulin; Insulin Receptor Substrate Proteins; Liver; Male; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Tyrosine; Vasoconstrictor Agents; Wortmannin | 2006 |
One-pot synthesis of genistein from tyrosine by coincubation of genetically engineered Escherichia coli and Saccharomyces cerevisiae cells.
Topics: Acetyl-CoA Carboxylase; Acyltransferases; Cloning, Molecular; Coenzyme A Ligases; Corynebacterium glutamicum; Coumaric Acids; Escherichia coli; Flavanones; Gene Expression; Genistein; Glycyrrhiza; Intramolecular Lyases; Isopropyl Thiogalactoside; Oxygenases; Phenylalanine Ammonia-Lyase; Promoter Regions, Genetic; Propionates; Pueraria; Saccharomyces cerevisiae; Streptomyces coelicolor; Temperature; Time Factors; Tyrosine | 2007 |
Tyrosine phosphorylation of rabphilin during long-lasting long-term potentiation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding Sites; Colforsin; Enzyme Inhibitors; Genistein; Hippocampus; Long-Term Potentiation; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neural Pathways; Organ Culture Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Presynaptic Terminals; Synaptic Transmission; Tyrosine | 2007 |
Anaplasma phagocytophilum AnkA is tyrosine-phosphorylated at EPIYA motifs and recruits SHP-1 during early infection.
Topics: Amino Acid Motifs; Amino Acid Sequence; Anaplasma phagocytophilum; Animals; Bacterial Proteins; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Genistein; HL-60 Cells; Humans; Immunoblotting; Immunoprecipitation; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyrimidines; Time Factors; Tyrosine | 2007 |
Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.
Topics: Apoptosis; Calcium Signaling; Cell Survival; Genistein; Humans; Hydrogen Peroxide; Immunoprecipitation; Necrosis; Oxidative Stress; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Protein Tyrosine Phosphatases; Pyrimidines; RNA Interference; RNA, Small Interfering; Time Factors; Transfection; TRPM Cation Channels; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells | 2007 |
Reversible protein tyrosine phosphorylation affects pollen germination and pollen tube growth via the actin cytoskeleton.
Topics: Actins; Arsenicals; Cell Differentiation; Cell Polarity; Cytoskeleton; Enzyme Inhibitors; Genistein; Germination; Lilium; Phosphorylation; Pollen; Pollen Tube; Protein Tyrosine Phosphatases; Protoplasts; Tyrosine | 2007 |
Inhibition of tyrosine kinase activity prevents the adhesive and cohesive properties of platelets and the expression of procoagulant activity in response to collagen.
Topics: Blood Coagulation; Blood Platelets; Collagen; Enzyme Activation; Fibrin; Flow Cytometry; Genistein; Humans; Microscopy, Electron; Phosphorylation; Platelet Activation; Platelet Adhesiveness; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Reference Values; Surface Properties; Thrombin; Tyrosine; Tyrphostins | 2008 |
Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blotting, Western; Caffeine; Calcimycin; Cattle; Dose-Response Relationship, Drug; Equol; Genistein; In Vitro Techniques; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Phytoestrogens; Potassium Chloride; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Pulmonary Veins; Tyrosine; Vasoconstriction | 2007 |
Specific tyrosine phosphorylation induced in Schistosoma mansoni miracidia by haemolymph from schistosome susceptible, but not resistant, Biomphalaria glabrata.
Topics: Animals; Biomphalaria; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Genistein; Hemolymph; Host-Parasite Interactions; Larva; Microscopy, Confocal; Phosphorylation; Protein-Tyrosine Kinases; Schistosoma mansoni; Signal Transduction; Tyrosine | 2008 |
Regulatory role of tyrosine phosphorylation in the swelling-activated chloride current in isolated rabbit articular chondrocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cartilage, Articular; Cell Size; Chloride Channels; Chondrocytes; Cyclopentanes; Genistein; Indans; Male; Osmosis; Patch-Clamp Techniques; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Vanadates | 2009 |
Ligation of CD44 with low-molecular-weight hyaluronan and a monoclonal antibody leads to inhibition of drug-induced apoptosis in a human myeloid cell line.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Genistein; Hematopoietic Stem Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Leukemia, Myeloid, Acute; Ligands; Molecular Weight; Myeloid Cells; Phosphorylation; Tyrosine | 2009 |
Clustering of neuronal K+-Cl- cotransporters in lipid rafts by tyrosine phosphorylation.
Topics: Amino Acid Sequence; Animals; Cell Line; Female; gamma-Aminobutyric Acid; Genistein; Hippocampus; Humans; K Cl- Cotransporters; Membrane Microdomains; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Wistar; Symporters; Tyrosine | 2009 |
The inhibitory mechanisms of the tyrosine kinase inhibitors herbimycin a, genistein, and tyrphostin B48 with regard to the function of the aryl hydrocarbon receptor in Caco-2 cells.
Topics: Active Transport, Cell Nucleus; Benzoquinones; Caco-2 Cells; Genistein; Humans; Intestinal Mucosa; Intestines; Lactams, Macrocyclic; Phosphorylation; Polychlorinated Dibenzodioxins; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Stability; Protein-Tyrosine Kinases; Receptors, Aryl Hydrocarbon; Reproducibility of Results; Rifabutin; Transcriptional Activation; Tyrosine; Tyrphostins | 2010 |
Regulation of human cardiac KCNQ1/KCNE1 channel by epidermal growth factor receptor kinase.
Topics: Animals; Cell Line; Electrophysiology; ErbB Receptors; Genistein; Humans; Ion Channel Gating; KCNQ1 Potassium Channel; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; src-Family Kinases; Tyrosine; Tyrphostins; Vanadates | 2010 |
Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers.
Topics: Bronchi; Cell Line; Cell Membrane Permeability; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Genistein; Green Fluorescent Proteins; Humans; Mannitol; Phosphorylation; Protein Kinase Inhibitors; Temperature; Tight Junctions; Tyrosine | 2010 |
Prothoracicotropic hormone induces tyrosine phosphorylation in prothoracic glands of the silkworm, Bombyx mori.
Topics: Animals; Antibodies; Bombyx; Ecdysteroids; Extracellular Signal-Regulated MAP Kinases; Genistein; Insect Hormones; Larva; Naphthalenes; Organophosphonates; Phosphorylation; Protein Phosphatase 2; src-Family Kinases; Tyrosine; Vanadates | 2011 |
Activation of the TASK-2 channel after cell swelling is dependent on tyrosine phosphorylation.
Topics: Animals; Cell Line; Cell Size; Enzyme Inhibitors; Female; Genistein; Humans; Hypotonic Solutions; Janus Kinases; Mice; Patch-Clamp Techniques; Phosphorylation; Potassium; Potassium Channels, Tandem Pore Domain; Protein-Tyrosine Kinases; Signal Transduction; STAT Transcription Factors; Tyrosine | 2010 |
Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Carcinoma, Hepatocellular; Cell Death; Cell Nucleus; Cell Survival; Cytoskeletal Proteins; Exportin 1 Protein; Genistein; Hep G2 Cells; Humans; Karyopherins; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fyn; Receptors, Cytoplasmic and Nuclear; Tyrosine | 2011 |
Inhibition of Kv4.3 by genistein via a tyrosine phosphorylation-independent mechanism.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Genistein; Ion Channel Gating; Isoflavones; Kinetics; Phosphorylation; Phytoestrogens; Potassium Channel Blockers; Protein Kinase Inhibitors; Shal Potassium Channels; Tyrosine | 2011 |
Inhibition of IGF-1 signaling by genistein: modulation of E-cadherin expression and downregulation of β-catenin signaling in hormone refractory PC-3 prostate cancer cells.
Topics: beta Catenin; Cadherins; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genistein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin-Like Growth Factor I; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Receptor, IGF Type 1; Signal Transduction; Tyrosine | 2012 |
Modulation of human cardiac transient outward potassium current by EGFR tyrosine kinase and Src-family kinases.
Topics: Action Potentials; Cells, Cultured; ErbB Receptors; Genistein; Heart Atria; HEK293 Cells; Humans; Mutagenesis, Site-Directed; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Protein Kinase Inhibitors; Shal Potassium Channels; Signal Transduction; src-Family Kinases; Tyrosine; Tyrphostins | 2012 |
JAK2 mediates the acute response to decreased cell volume in mouse preimplantation embryos by activating NHE1.
Topics: Animals; Blastocyst; Calmodulin; Cation Transport Proteins; Cell Size; Female; Genistein; Guanidines; Janus Kinase 2; Male; Mice; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones; Superovulation; Type C Phospholipases; Tyrosine | 2013 |
Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Box Protein O1; Forkhead Transcription Factors; Genistein; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress; Sirtuin 1; Streptozocin; Superoxides; Tyrosine; Wound Healing | 2013 |
Positive and negative regulation of insulin action by genistein in the endothelium.
Topics: Animals; Aorta; Endothelin-1; Endothelium, Vascular; Genistein; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Interleukin-6; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Cell Adhesion Molecule-1; Vasodilation | 2013 |
Genistein promotes insulin action through adenosine monophosphate-activated protein kinase activation and p70 ribosomal protein S6 kinase 1 inhibition in the skeletal muscle of mice fed a high energy diet.
Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Down-Regulation; Energy Intake; Fructose; Genistein; Glycine max; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred Strains; Muscle, Skeletal; Phosphorylation; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tyrosine | 2012 |
Tumor necrosis factor α stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells.
Topics: Cells, Cultured; Dental Pulp; Genistein; Humans; Interleukin-1; NF-kappa B; Phosphorylation; Plasminogen Activators; Pyrrolidines; Rifabutin; Thiocarbamates; Tumor Necrosis Factor-alpha; Tyrosine; Vanadates | 2012 |
Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord contributes to chronic visceral pain in rats.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Excitatory Amino Acid Antagonists; Genistein; Irritable Bowel Syndrome; Male; Pain Measurement; Phenols; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors; Tyrosine; Visceral Pain | 2014 |
Membrane depolarization-induced RhoA/Rho-associated kinase activation and sustained contraction of rat caudal arterial smooth muscle involves genistein-sensitive tyrosine phosphorylation.
Topics: Amides; Animals; Arteries; Calcium; Genistein; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphorylation; Potassium; Protein Kinase Inhibitors; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Tyrosine; Vanadates | 2013 |
Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation.
Topics: Caco-2 Cells; Epithelial Cells; Gene Expression Regulation; Genistein; Humans; Intestinal Mucosa; Isoflavones; MAP Kinase Signaling System; NF-kappa B; Phosphorylation; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
Tyrosine phosphorylation of β-catenin affects its subcellular localization and transcriptional activity of β-catenin in Hela and Bcap-37 cells.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Genistein; HeLa Cells; Humans; Molecular Structure; Phosphorylation; Structure-Activity Relationship; Tyrosine | 2014 |
Genistein attenuates D-GalN induced liver fibrosis/chronic liver damage in rats by blocking the TGF-β/Smad signaling pathways.
Topics: Animals; Blotting, Western; Chronic Disease; Collagen; Galactosamine; Genistein; Hepatic Stellate Cells; In Situ Nick-End Labeling; Liver; Liver Cirrhosis; Male; Rats, Wistar; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Tyrosine | 2017 |
Tyrosine Phosphorylation of NR2B Contributes to Chronic Migraines via Increased Expression of CGRP in Rats.
Topics: Animals; Calcitonin; Calcitonin Gene-Related Peptide; Disease Models, Animal; Genistein; Humans; Hyperalgesia; Male; Migraine Disorders; Neurons; Pain Measurement; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2017 |