tyrosine has been researched along with geldanamycin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 13 (76.47) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heruth, DP; Leyva, A; Rothberg, PG; Wetmore, LA | 1 |
| Amaral, MC; Kumar, G; Miles, S; Nel, AE | 1 |
| Bolen, JB; Eiseman, E; Penhallow, RC; Shakarjian, MP | 1 |
| Gear, AR; Polanowska-Grabowska, R; Suttitanamongkol, S | 1 |
| An, WG; Bonvini, P; Dunach, M; Garcia de Herreros, A; Neckers, LM; Nguyen, P; Rosolen, A; Trepel, J | 1 |
| Cartledge, K; Dunn, AR; Hartson, SD; Matts, RL; Scholz, GM; Volk, L | 1 |
| Ghosh, SK; Johnson, BE; Kijima, T; Lin, J; Ma, PC; Maulik, G; Salgia, R; Schaefer, E; Shapiro, GI; Tibaldi, E | 1 |
| Fried, VA; Patel, K; Sehgal, PB; Shah, M | 1 |
| Adinolfi, E; Di Virgilio, F; Kim, M; Surprenant, A; Young, MT | 1 |
| Aitken, RJ; Ecroyd, H; Jones, RC | 1 |
| Chen, L; Qing, K; Si, Y; Srivastava, A; Tan, M; Zhong, L | 1 |
| Houle, F; Huot, J; Le Boeuf, F | 1 |
| Emala, CW; Hirshman, CA; Panettieri, RA; Pertel, T; Zhu, D | 1 |
| Chen, JF; He, JC; Huang, QY; Shen, HY; Wang, Y | 1 |
| Crèvecoeur, J; Gloire, G; Merville, MP; Piette, J | 1 |
| Emmanouilidou, E; Stefanis, L; Vekrellis, K | 1 |
| Cappabianca, L; Cea, G; Chioda, A; Farina, AR; Gulino, A; Mackay, AR; Pedone, C; Pensato, S; Romanelli, A; Tacconelli, A | 1 |
17 other study(ies) available for tyrosine and geldanamycin
| Article | Year |
|---|---|
Influence of protein tyrosine phosphorylation on the expression of the c-myc oncogene in cancer of the large bowel.
Topics: Benzoquinones; Cell Count; Cell Line; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Genistein; Half-Life; Humans; Isoflavones; Lactams, Macrocyclic; Novobiocin; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; RNA, Messenger; Topoisomerase II Inhibitors; Tyrosine; Vanadates | 1995 |
Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42MAPK/ERK-2 in Kaposi's cells. Evidence that this pathway is important in Kaposi cell growth.
Topics: Acquired Immunodeficiency Syndrome; Benzoquinones; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Membrane; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Activation; Growth Inhibitors; Humans; Kinetics; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Oncostatin M; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinones; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Tyrosine; Umbilical Veins | 1993 |
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in a rat mast cell line. Impairment of tyrosine kinase-dependent signal transduction and the subsequent degranulation response.
Topics: Animals; Benzoquinones; Cell Degranulation; Cell Line; Econazole; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin E; Lactams, Macrocyclic; Lovastatin; Mast Cells; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rats; Receptors, Fc; Signal Transduction; Tyrosine | 1993 |
Geldanamycin disrupts platelet-membrane structure, leading to membrane permeabilization and inhibition of platelet aggregation.
Topics: Adenine Nucleotides; Benzoquinones; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Dose-Response Relationship, Drug; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Phosphorylation; Platelet Aggregation Inhibitors; Quinones; Serotonin; Signal Transduction; Tyrosine | 2000 |
Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription.
Topics: Antibiotics, Antineoplastic; Benzoquinones; beta Catenin; Cadherins; Cell Movement; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Humans; Lactams, Macrocyclic; Melanoma; Multienzyme Complexes; Nerve Tissue Proteins; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Quinones; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, ErbB-2; Receptors, Cell Surface; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tyrosine | 2001 |
The molecular chaperone Hsp90 is required for signal transduction by wild-type Hck and maintenance of its constitutively active counterpart.
Topics: Animals; Benzoquinones; Catalytic Domain; Cell Adhesion; Cells, Cultured; Enzyme Inhibitors; Focal Adhesion Kinase 2; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Oncogene Protein v-cbl; Phosphorylation; Protein Folding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Quinones; Retroviridae Proteins, Oncogenic; Signal Transduction; src-Family Kinases; Tyrosine | 2001 |
Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
Topics: Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Carcinoma, Small Cell; Cell Cycle; Cell Movement; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Hepatocyte Growth Factor; Humans; Immunoblotting; Lactams, Macrocyclic; Lung Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-met; Quinones; Reactive Oxygen Species; Signal Transduction; Time Factors; Tumor Cells, Cultured; Tyrosine | 2002 |
Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever.
Topics: Animals; Benzoquinones; beta-Cyclodextrins; Cattle; Caveolin 1; Caveolins; Cell Fractionation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cyclodextrins; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Endothelium, Vascular; Filipin; Genes, Reporter; Heat-Shock Proteins; Hepatocytes; Hot Temperature; HSP90 Heat-Shock Proteins; Humans; Interferon-gamma; Interleukin-6; Isomerases; Lactams, Macrocyclic; Macromolecular Substances; Membrane Microdomains; Molecular Chaperones; Phosphorylation; Protein Binding; Protein Disulfide-Isomerases; Protein Transport; Quinones; Respiratory Mucosa; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tyrosine | 2002 |
Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors.
Topics: Benzoquinones; Cell Line; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Phosphorylation; Quinones; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Tyrosine | 2003 |
Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation.
Topics: Amino Acid Sequence; Animals; Benzoquinones; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Male; Mammals; Mice; Molecular Sequence Data; Phosphorylation; Quinones; Rats; Rats, Wistar; Sperm Capacitation; Spermatozoa; Tyrosine | 2003 |
Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90.
Topics: Benzoquinones; Blotting, Western; Dependovirus; DNA Replication; DNA, Complementary; Down-Regulation; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Genes, Viral; Genetic Therapy; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Models, Biological; Oligonucleotides, Antisense; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Quinones; Tacrolimus Binding Proteins; Transfection; Transgenes; Tyrosine; Tyrphostins | 2004 |
Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities.
Topics: Amides; Benzoquinones; CD18 Antigens; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; DNA, Complementary; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Gene Transfer Techniques; Genes, Dominant; Green Fluorescent Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Luminescent Proteins; Mutation; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Pyridines; Quinones; rhoA GTP-Binding Protein; src-Family Kinases; Time Factors; Tyrosine; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2; Vinculin | 2004 |
Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS.
Topics: Adjuvants, Immunologic; Adrenergic beta-Agonists; Benzoquinones; Cells, Cultured; Cholera Toxin; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gs; Humans; Isoproterenol; Lactams, Macrocyclic; Myocytes, Smooth Muscle; Phosphorylation; Quinones; src-Family Kinases; Trachea; Tyrosine | 2005 |
Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzoquinones; Blotting, Western; Brain; Cell Death; Cell Nucleus; Cytosol; Disease Models, Animal; DNA-Binding Proteins; Dopamine; Dopamine Agents; Enzyme Inhibitors; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Immunohistochemistry; Lactams, Macrocyclic; Male; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Chaperones; Neoplasm Proteins; Neurons; Neurotoxins; Parkinson Disease; Quinones; Time Factors; Transcription Factors; Tyrosine; Tyrosine 3-Monooxygenase | 2005 |
Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; DNA; Gene Expression Regulation; Genes, src; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Jurkat Cells; Lactams, Macrocyclic; Molecular Structure; NF-kappa B; Phosphorylation; Protein Binding; RNA, Messenger; Tyrosine; Vanadates | 2008 |
Cell-produced alpha-synuclein oligomers are targeted to, and impair, the 26S proteasome.
Topics: Alanine; alpha-Synuclein; Ammonium Chloride; Animals; Benzoquinones; Cerebral Cortex; Chromatography, Gel; Coloring Agents; Congo Red; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lactams, Macrocyclic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; PC12 Cells; Proteasome Endopeptidase Complex; Protein Folding; Rats; Transfection; Tyrosine | 2010 |
The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells.
Topics: Alternative Splicing; Antigens, Surface; Benzoquinones; Enzyme Stability; Genes, Tumor Suppressor; HSP90 Heat-Shock Proteins; Humans; Isoenzymes; Lactams, Macrocyclic; Neuroblastoma; Oncogenes; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Transport; Receptor, trkA; Transfection; Tumor Cells, Cultured; Tyrosine | 2009 |