tyrosine has been researched along with endothelin-1 in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 11 (22.00) | 18.2507 |
2000's | 28 (56.00) | 29.6817 |
2010's | 11 (22.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Agrawal, DK; Chisholm, LJ; Edwards, JD; Pearson, TJ | 1 |
Coroneos, EJ; Dunn, MJ; Kester, M; Maclouf, J; Thomas, P | 1 |
Adamson, P; Cazaubon, S; Chaverot, N; Couraud, PO; Girault, JA; Romero, IA; Strosberg, AD | 1 |
Cazaubon, S; Chaverot, N; Couraud, PO; Schröder, C; Strosberg, AD; Teixeira, A | 1 |
Desmarets, J; Frelin, C | 1 |
DeFea, K; Li, J; Roth, RA | 1 |
El-Mowafy, AM; White, RE | 1 |
Baba, A; Koyama, Y | 1 |
Calcerrada, MC; Catalán, RE; Martínez, AM; Pérez, MJ | 1 |
Eguchi, S; Hirata, Y; Iwasaki, H; Marumo, F; Ueno, H | 1 |
Catalán, RE; Gargiulo, L; Liras, A; Martínez, AM | 1 |
Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Sasaki, M; Sato, A; Tomita, F | 1 |
Bagnato, A; Catt, KJ; Tecce, R; Vacca, F | 1 |
Baba, A; Hashimoto, H; Koyama, Y; Matsuda, T; Yoshioka, Y | 1 |
Catalán, RE; Liras, A; Martínez, AM | 1 |
Huang, J; Imamura, T; Ishibashi , KI; Olefsky, JM; Sharma, PM; Ugi, S | 1 |
Belcastro, R; Copland, I; Frndova, H; Hoidal, JR; Jankov, RP; Luo, X; Lye, SJ; Post, M; Tanswell, AK | 1 |
Bekker, JM; Black, SM; Fineman, JR; McMullan, DM; Wedgwood, S | 1 |
Carrasco Martín, C; Casado, S; Córdoba, M; Farré, J; García-Mendez, A; Jiménez Mateos-Caceres, P; López-Farré, A; Millás, I; Molero, L; Navarro, F | 1 |
Hoogduijn, MJ; Smit, NP; Thody, AJ; van der Laarse, A; van Nieuwpoort, AF; Wood, JM | 1 |
Hashimoto, N; Kawanabe, Y; Masaki, T | 1 |
Dixon, JL; Katwa, LC; Lee, DL; Reddy, HK; Sturek, M; Voelker, DJ; Wamhoff, BR | 1 |
Fukuda, K; Ieda, M; Kimura, K; Kodama, H; Ogawa, S; Owada, KM; Tahara, S; Takahashi, E; Tomita, Y; Vuori, K | 1 |
Itoh, H; Miyamoto, Y; Yamauchi, J | 1 |
Nagy, LE; Rachdaoui, N | 1 |
Bagnato, A; Di Castro, V; Natali, PG; Nicotra, MR; Rosanò, L; Spinella, F | 1 |
Huang, J; Kontos, CD; Liu, S; Premont, RT; Rockey, DC | 1 |
Fukui, K; Kobayashi, Y; Nishi, Y; Takashima, H; Tamaoki, H; Teno, N; Uchiyama, S | 1 |
Chambers, CE; Demers, LM; Hartman, G; King, N; Kozak, M; McCann, J; McNulty, PH; Scott, S; Sinoway, LI | 1 |
Ikeda, K; Xu, JW; Yamori, Y | 1 |
Arteel, GE; Cai, L; Du, Y; Kang, YJ; Li, Y; Saari, JT; Song, Y; Wang, J | 1 |
Lominadze, D; Moshal, KS; Ovechkin, AV; Tyagi, N; Tyagi, SC | 1 |
Elmendorf, JS; Strawbridge, AB | 1 |
Capobianco, E; González, E; Higa, R; Jawerbaum, A; Martínez, N; Pustovrh, C; Sinner, D; White, V | 1 |
Chao, HH; Chen, YL; Cheng, TH; Chiu, WT; Hong, HJ; Lin, JW; Liu, JC; Shyu, KG; Wu, CH | 1 |
Bereswill, S; Bien, S; Escher, F; Felix, SB; Gratz, M; Heimesaat, MM; Krieg, T; Kroemer, HK; Riad, A; Schultheiss, HP; Tschöpe, C; Westermann, D | 1 |
Slutsky, AS; Syeda, F; Tullis, E; Zhang, H | 1 |
Bachelard, H; Badeau, M; Bourgoin, F; Larivière, R; Mélançon, S; Nadeau, A; Pitre, M | 1 |
Chung, SK; Chung, SS; Leung, JW | 1 |
Cao, W; Glushakov, A; Martynyuk, AE; Mecca, AP; Seubert, CN; Shah, HP; Shi, P; Sumners, C | 1 |
Hsieh, HL; Wang, HH; Yang, CM | 1 |
Benigni, A; Bisighini, C; Cattaneo, S; Corna, D; Fiordaliso, F; Lionetti, V; Pagani, C; Remuzzi, G; Rottoli, D; Salio, M; Zambelli, V; Zoja, C | 1 |
Bastia, E; Galassi, F; Giambene, B; Impagnatiello, F; Lanzi, C; Masini, E; Ongini, E; Pini, A; Somma, T | 1 |
Gao, X; Guo, X; Huang, F; Liu, B; Liu, K; Wang, M; Zhang, D | 1 |
Hwang, SM; Kang, DG; Kim, JS; Lee, HS; Lee, SM; Lee, YJ; Yoon, JJ | 1 |
Fung, ML; Lau, TY; Leung, TM; Liao, L; Liong, EC; Nanji, AA; Tipoe, GL; Xiao, J | 1 |
Bachelard, H; Badeau, M; Bourgoin, F; Larivière, R; Nadeau, A; Pitre, M | 1 |
Chibbar, R; Lane, N; Ndisang, JF | 1 |
Evans, TRJ; Jones, R; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM | 1 |
Kokot, T; Muc-Wierzgon, M; Sosada, K; Swietochowska, E; Zurawinski, W | 1 |
1 trial(s) available for tyrosine and endothelin-1
Article | Year |
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Effects of supplemental oxygen administration on coronary blood flow in patients undergoing cardiac catheterization.
Topics: Acetylcholine; Adenosine; Adult; Aged; Cardiac Catheterization; Coronary Circulation; Coronary Disease; Drug Interactions; Endothelin-1; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxygen; Tyrosine; Vasodilator Agents | 2005 |
49 other study(ies) available for tyrosine and endothelin-1
Article | Year |
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Endothelin-1 induces tyrosine phosphorylation in human blood monocytes.
Topics: Adult; Antibodies, Blocking; Benzoquinones; Blotting, Western; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Female; Genistein; Humans; In Vitro Techniques; Isoflavones; Janus Kinase 1; Lactams, Macrocyclic; Male; Monocytes; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Quinones; Receptors, Endothelin; Rifabutin; src-Family Kinases; Time Factors; Tyrosine | 1996 |
Calcium-regulated protein tyrosine phosphorylation is required for endothelin-1 to induce prostaglandin endoperoxide synthase-2 mRNA expression and protein synthesis in mesangial cells.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cells, Cultured; Chelating Agents; Cytosol; Endothelin-1; Enzyme Inhibitors; Gallic Acid; Gene Expression; Glomerular Mesangium; Ionomycin; Ionophores; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Proteins; Rats; RNA, Messenger; Signal Transduction; Thapsigargin; Tyrosine | 1997 |
Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathways.
Topics: Actins; Adaptor Proteins, Signal Transducing; Aluminum Compounds; Animals; Astrocytes; Cell Adhesion Molecules; Cell Division; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cytoskeletal Proteins; Cytoskeleton; DNA; Endothelin-1; ErbB Receptors; Fetus; Fluorides; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; GTP-Binding Proteins; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Rabbits; Rats; rho GTP-Binding Proteins; Signal Transduction; src Homology Domains; src-Family Kinases; Stress, Mechanical; Tyrosine | 1997 |
Requirement of caveolae microdomains in extracellular signal-regulated kinase and focal adhesion kinase activation induced by endothelin-1 in primary astrocytes.
Topics: Actins; Animals; Anti-Bacterial Agents; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Caveolin 1; Caveolins; Cell Adhesion; Cell Adhesion Molecules; Cell Compartmentation; Cells, Cultured; Cytoskeleton; Endothelin-1; Enzyme Activation; Extracellular Space; Filipin; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein-Tyrosine Kinases; Rats; Signal Transduction; Tyrosine | 1999 |
High affinity interaction of endothelin-3 with recombinant ETA receptors.
Topics: Animals; Azepines; Binding, Competitive; Cattle; Cell Line; Cell Membrane; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Indoles; Kinetics; Ligands; Peptide Fragments; Peptides, Cyclic; Protein Isoforms; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Recombinant Proteins; Transfection; Tyrosine; Viper Venoms | 1999 |
Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway.
Topics: 3T3 Cells; Adipocytes; Animals; Endothelin-1; Flavonoids; Insulin; Insulin Receptor Substrate Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sirolimus; Tyrosine | 1999 |
Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: reversal of endothelin-1 stimulatory effects.
Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Inhibitors; Muscle, Smooth, Vascular; Phosphorylation; Resveratrol; Stilbenes; Swine; Tyrosine | 1999 |
Endothelin-induced protein tyrosine phosphorylation of cultured astrocytes: its relationship to cytoskeletal actin organization.
Topics: Actins; Animals; Astrocytes; Calcium; Cells, Cultured; Cytoskeleton; Endothelin-1; Endothelin-3; Mice; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Proteins; Rabbits; Rats; Rats, Wistar; Tyrosine; Virulence Factors, Bordetella | 1999 |
Endothelin stimulates tyrosine phosphorylation of p125FAK and p130Cas in rat cerebral cortex.
Topics: Animals; Calcium; Cell Adhesion Molecules; Cerebral Cortex; Crk-Associated Substrate Protein; Endothelin Receptor Antagonists; Endothelin-1; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Male; Oligopeptides; Peptides, Cyclic; Phosphoproteins; Phosphorylation; Piperidines; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Wistar; Retinoblastoma-Like Protein p130; Tyrosine | 1999 |
Endothelin-mediated vascular growth requires p42/p44 mitogen-activated protein kinase and p70 S6 kinase cascades via transactivation of epidermal growth factor receptor.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Endothelins; Enzyme Activation; ErbB Receptors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Development; Muscle, Smooth, Vascular; Oncogene Protein p21(ras); Phosphorylation; Rats; Receptor, Endothelin A; Receptors, Endothelin; Ribosomal Protein S6 Kinases; Transcriptional Activation; Tyrosine | 1999 |
Endothelin-1 effect on tyrosine phosphorylation and on tyrosine phosphatase (PTP-1C) translocation in rabbit platelets.
Topics: Animals; Biological Transport; Blood Platelets; Dose-Response Relationship, Drug; Endothelin-1; Phosphorylation; Platelet Activation; Protein Tyrosine Phosphatases; Rabbits; Signal Transduction; Time Factors; Tyrosine | 1999 |
Agonist-dependent difference in the mechanisms involved in Ca2+ sensitization of smooth muscle of porcine coronary artery.
Topics: Animals; Calcium; Calcium Signaling; Carbachol; Cardiotonic Agents; Coronary Vessels; Endothelin-1; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Rabbits; rho GTP-Binding Proteins; Swine; Tyrosine | 2000 |
Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Cell Division; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Ovarian Neoplasms; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proteins; Quinazolines; Receptor, Endothelin A; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components.
Topics: Androstadienes; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Bradykinin; Bucladesine; Cerebral Cortex; Chelating Agents; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Paxillin; Pertussis Toxin; Phosphoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Synergistic effect of endothelin-1 and serotonin in rabbit platelets: effect on tyrosine phosphorylation.
Topics: Animals; Antihypertensive Agents; Blood Platelets; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Free Radical Scavengers; Peptides, Cyclic; Phosphorylation; Protein Binding; Rabbits; Serotonin; Tyrosine; Vasoconstrictor Agents; Viper Venoms | 2000 |
Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; Animals; Biological Transport; Deoxyglucose; Drug Interactions; Endothelin Receptor Antagonists; Endothelin-1; Glucose Transporter Type 4; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Intramolecular Transferases; Mice; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-cbl; Receptor, Endothelin A; Signal Transduction; Tyrosine; Ubiquitin-Protein Ligases | 2001 |
Gadolinium chloride inhibits pulmonary macrophage influx and prevents O(2)-induced pulmonary hypertension in the neonatal rat.
Topics: Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Cell Movement; Cells, Cultured; Dinoprost; Endothelin-1; F2-Isoprostanes; Gadolinium; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infant, Newborn; Macrophages, Alveolar; Oxygen; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cells, Cultured; Dioxoles; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Humans; Hypertension, Pulmonary; Lung; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Receptor, Endothelin A; Secondary Prevention; Sheep; Superoxides; Tyrosine | 2001 |
Endothelin-1 induced proinflammatory markers in the myocardium and leukocytes of guinea-pigs: role of glycoprotein IIB/IIIA receptors.
Topics: Animals; Blood Platelets; Cells, Cultured; Cyclooxygenase 2; Endothelin-1; Guinea Pigs; Isoenzymes; Leukocytes, Mononuclear; Male; Myocardium; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandin-Endoperoxide Synthases; Stimulation, Chemical; Thromboplastin; Tirofiban; Tyrosine | 2003 |
Melanin has a role in Ca2+ homeostasis in human melanocytes.
Topics: Ammonium Chloride; Black People; Calcium; Calcium Chloride; Calcium Signaling; Cells, Cultured; Endothelin-1; Epidermal Cells; Epidermis; Homeostasis; Humans; Intracellular Fluid; Male; Melanins; Melanocytes; Tyrosine; White People | 2003 |
Involvements of voltage-independent Ca2+ channels and phosphoinositide 3-kinase in endothelin-1-induced PYK2 tyrosine phosphorylation.
Topics: Acetamides; Androstadienes; Animals; Calcium; Calcium Channels; Cells, Cultured; Chromones; Drug Interactions; Endothelin-1; Enzyme Inhibitors; Focal Adhesion Kinase 2; Imidazoles; Isoquinolines; Morpholines; Muscle, Smooth, Vascular; Nifedipine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Wortmannin | 2003 |
Increased endothelin-induced Ca2+ signaling, tyrosine phosphorylation, and coronary artery disease in diabetic dyslipidemic Swine are prevented by atorvastatin.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Calcium; Calcium Signaling; Coronary Artery Disease; Diabetes Complications; Diet; Disease Models, Animal; Endothelin-1; Endothelins; Heptanoic Acids; Hyperlipidemias; Male; Phosphorylation; Pyrroles; Receptor, Endothelin A; Receptors, Endothelin; Swine; Tyrosine | 2003 |
Selective involvement of p130Cas/Crk/Pyk2/c-Src in endothelin-1-induced JNK activation.
Topics: Animals; Calcium; Cells, Cultured; Crk-Associated Substrate Protein; CSK Tyrosine-Protein Kinase; Endothelin-1; Enzyme Activation; Focal Adhesion Kinase 2; Focal Adhesions; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mutation; Myocytes, Cardiac; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Wistar; Retinoblastoma-Like Protein p130; src-Family Kinases; Transcriptional Activation; Tyrosine | 2003 |
Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.
Topics: Amino Acid Sequence; Catalytic Domain; cdc42 GTP-Binding Protein; Cell Line; Cell Movement; Cells, Cultured; DNA, Complementary; Endothelin-1; Endothelins; Enzyme Activation; Genes, Dominant; Glutathione Transferase; Guanine Nucleotide Exchange Factors; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Sequence Data; Mutation; Phosphorylation; Proline; Protein Binding; Proteins; rac1 GTP-Binding Protein; Receptor, Endothelin A; Receptors, Endothelin; Recombinant Fusion Proteins; Recombinant Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Sequence Homology, Amino Acid; Signal Transduction; src-Family Kinases; Time Factors; Transfection; Tyrosine | 2003 |
Endothelin-1-stimulated glucose uptake is desensitized by tumor necrosis factor-alpha in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Antineoplastic Agents; Drug Interactions; Endothelin-1; Focal Adhesion Kinase 2; Glucose; Glucose Transporter Type 4; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Homeostasis; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Endothelin A; Receptors, Endothelin; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells.
Topics: Animals; Cell Division; Cell Line, Tumor; Connexin 43; Disease Progression; Endothelin-1; Female; Humans; Immunoblotting; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Phosphorylation; Precipitin Tests; Time Factors; Tyrosine | 2003 |
Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.
Topics: Animals; Culture Media, Serum-Free; Endothelial Cells; Endothelin-1; Enzyme Activation; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Time Factors; Tyrosine | 2003 |
Hydrophobic core around tyrosine for human endothelin-1 investigated by photochemically induced dynamic nuclear polarization nuclear magnetic resonance and matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
Topics: Amino Acid Sequence; Crystallization; Crystallography, X-Ray; Endothelin-1; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Photochemistry; Protein Folding; Protein Structure, Tertiary; Solutions; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thermodynamics; Tyrosine; Ultracentrifugation | 2004 |
Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Anilides; Animals; Aorta, Thoracic; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Genistein; Hypertension; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; PPAR gamma; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Signal Transduction; Stroke; Superoxides; Tyrosine; Vasoconstrictor Agents | 2004 |
Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury.
Topics: Aldehydes; Animals; Blotting, Northern; Blotting, Western; Cardiovascular Diseases; Copper; Diabetes Mellitus, Experimental; Endothelin-1; Glutathione; Immunohistochemistry; Interleukin-6; Iron; Metallothionein; Mice; Mice, Transgenic; Myocardium; Oxidative Stress; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Zinc | 2005 |
Homocysteine-dependent cardiac remodeling and endothelial-myocyte coupling in a 2 kidney, 1 clip Goldblatt hypertension mouse model.
Topics: Acetylcholine; Animals; Blotting, Western; Collagen; Endothelin-1; Endothelium, Vascular; Fibrosis; Homocysteine; Hypertension, Renovascular; Hypoglycemic Agents; Kidney; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Nitroprusside; PPAR gamma; Proteinuria; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Tyrosine; Vasodilator Agents; Ventricular Remodeling | 2005 |
Endothelin-1 impairs glucose transporter trafficking via a membrane-based mechanism.
Topics: 3T3-L1 Cells; Animals; Cell Membrane; Endothelin-1; Glucose Transporter Type 4; Insulin; Mice; Monosaccharide Transport Proteins; Oncogene Protein v-cbl; Osmotic Pressure; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Signal Transduction; Tyrosine | 2006 |
Peroxynitrites and impaired modulation of nitric oxide concentrations in embryos from diabetic rats during early organogenesis.
Topics: Animals; Diabetes Mellitus, Experimental; Embryo, Mammalian; Endothelin-1; Female; Immunohistochemistry; Nitrates; Nitric Oxide; Nitrites; Organogenesis; Pregnancy; Pregnancy in Diabetics; Prostaglandin D2; Rats; Rats, Wistar; Tyrosine | 2005 |
Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Blotting, Northern; Blotting, Western; Butadienes; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Endothelin-1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Male; Metalloendopeptidases; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Signal Transduction; Transcriptional Activation; Tyrosine; Tyrphostins | 2007 |
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Endothelin-1; GATA4 Transcription Factor; In Situ Nick-End Labeling; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Mice, Knockout; Toll-Like Receptor 4; Tyrosine; Ventricular Dysfunction, Left | 2008 |
Human neutrophil peptides upregulate expression of COX-2 and endothelin-1 by inducing oxidative stress.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Endothelial Cells; Endothelin-1; Epoprostenol; Free Radical Scavengers; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neutrophils; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Kinase Inhibitors; Time Factors; Tyrosine; Up-Regulation | 2008 |
Endothelial and vascular dysfunctions and insulin resistance in rats fed a high-fat, high-sucrose diet.
Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Deoxyglucose; Diet; Dietary Fats; Endothelin-1; Endothelium, Vascular; Fatty Acids, Nonesterified; Fluorescent Antibody Technique; Glucose Clamp Technique; Heart Rate; Insulin; Insulin Resistance; Male; Obesity; Organ Size; Rats; Rats, Sprague-Dawley; Sucrose; Triglycerides; Tyrosine; Vascular Diseases; Vascular Resistance | 2008 |
Endothelial endothelin-1 over-expression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion.
Topics: Animals; Aquaporin 4; Atrasentan; Blood-Brain Barrier; Brain; Capillary Permeability; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Immunoglobulins; Infarction, Middle Cerebral Artery; Matrix Metalloproteinase 2; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Occludin; Oxidative Stress; Promoter Regions, Genetic; Pyrrolidines; Receptor, Endothelin A; Receptor, TIE-1; Superoxides; Tyrosine; Water | 2009 |
Halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine produces beneficial effects in experimental stroke and seizures.
Topics: Animals; Blood Pressure; Brain; Caspase 3; Disease Models, Animal; Endothelin-1; Epilepsy; Heart Rate; Hydrocarbons, Brominated; Infarction, Middle Cerebral Artery; Male; Motor Activity; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stroke; Tyrosine | 2011 |
Nitric oxide production by endothelin-1 enhances astrocytic migration via the tyrosine nitration of matrix metalloproteinase-9.
Topics: Animals; Astrocytes; Cell Movement; Endothelin-1; Enzyme Activation; Enzyme Induction; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 3; Models, Biological; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrosation; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Rats; Receptor, Endothelin B; Tyrosine; Up-Regulation | 2011 |
Distinct cardiac and renal effects of ETA receptor antagonist and ACE inhibitor in experimental type 2 diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Cell Count; Collagen Type III; Diabetes Mellitus, Type 2; Endothelin A Receptor Antagonists; Endothelin-1; Heart; Hemodynamics; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Muscle Cells; Myocardium; Rats; Rats, Zucker; Real-Time Polymerase Chain Reaction; Receptors, Vascular Endothelial Growth Factor; Survival; Tyrosine; Vascular Endothelial Growth Factor A | 2011 |
The nitric oxide donating triamcinolone acetonide NCX 434 does not increase intraocular pressure and reduces endothelin-1 induced biochemical and functional changes in the rabbit eye.
Topics: Animals; Caspase 3; Cytokines; Electroretinography; Endothelin-1; Glutathione; Hemodynamics; Intraocular Pressure; Intravitreal Injections; Laser-Doppler Flowmetry; Male; Nitrates; Nitric Oxide Donors; Ophthalmic Artery; Optic Disk; Rabbits; Reperfusion Injury; Retina; Retinal Diseases; Superoxide Dismutase; Tonometry, Ocular; Triamcinolone Acetonide; Tyrosine | 2012 |
Positive and negative regulation of insulin action by genistein in the endothelium.
Topics: Animals; Aorta; Endothelin-1; Endothelium, Vascular; Genistein; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Interleukin-6; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Palmitates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Cell Adhesion Molecule-1; Vasodilation | 2013 |
Anti-diabetic atherosclerosis effect of Prunella vulgaris in db/db mice with type 2 diabetes.
Topics: Acetylcholine; Animals; Aorta; Atherosclerosis; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol, Dietary; Creatinine; Diabetes Complications; Diabetes Mellitus, Type 2; Diet, High-Fat; Dose-Response Relationship, Drug; Endothelin-1; Hyperglycemia; Hypertrophy; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Lipids; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Phytotherapy; Plant Extracts; Prunella; Transforming Growth Factor beta1; Tunica Intima; Tunica Media; Tyrosine; Vascular Cell Adhesion Molecule-1; Vasodilation | 2012 |
Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B.
Topics: Alanine Transaminase; Animals; Biomarkers; Blotting, Western; Chronic Disease; Dinoprost; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Endothelin-1; Gene Expression Regulation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Male; NF-kappa B; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factor AP-1; Tyrosine; Vascular Endothelial Growth Factor A | 2013 |
Effects of tempol on endothelial and vascular dysfunctions and insulin resistance induced by a high-fat high-sucrose diet in the rat.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Mass Index; Cyclic N-Oxides; Diet, High-Fat; Dietary Sucrose; Endothelin-1; Endothelins; Endothelium, Vascular; Glucose; Glucose Transporter Type 4; Heart Rate; Hemodynamics; Inflammation; Insulin; Insulin Resistance; Male; Muscle, Skeletal; NADPH Oxidases; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Spin Labels; Tyrosine | 2013 |
Heme oxygenase suppresses markers of heart failure and ameliorates cardiomyopathy in L-NAME-induced hypertension.
Topics: Adiponectin; Aldosterone; Animals; Antioxidants; Arginine; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cardiomyopathies; Cardiotonic Agents; Chemokine CCL2; Chemokine CCL3; Cyclic GMP; Dinoprost; Endothelin-1; Enzyme Induction; Extracellular Matrix Proteins; Heart Failure; Heme; Heme Oxygenase (Decyclizing); Hypertension; Interleukin-1beta; Interleukin-6; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
Microparticles from vascular endothelial growth factor pathway inhibitor-treated cancer patients mediate endothelial cell injury.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Cardiotoxicity; Cell Communication; Cell-Derived Microparticles; Cells, Cultured; Endothelial Cells; Endothelin-1; Female; Humans; Male; Middle Aged; Neoplasms; Nitric Oxide; Reactive Oxygen Species; Signal Transduction; Tyrosine; Vascular Endothelial Growth Factor A | 2019 |
The influence of the low-energy defibrillating impulse on the endothelin-1 concentration in the left heart ventricle and blood serum of the healthy rabbits.
Topics: Animals; Blood Pressure; Electric Stimulation; Endothelin-1; Fatty Acid-Binding Proteins; Female; Heart Ventricles; Male; Myocardium; Rabbits; Tyrosine; Ventricular Function | 2019 |