tyrosine has been researched along with cysteine in 871 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 262 (30.08) | 18.7374 |
| 1990's | 168 (19.29) | 18.2507 |
| 2000's | 277 (31.80) | 29.6817 |
| 2010's | 135 (15.50) | 24.3611 |
| 2020's | 29 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Hannah, R; Sahib, MK | 1 |
| Atassi, MZ | 1 |
| Gupta, VJ; Wilcken, DE | 1 |
| Salemnick, G; Stöhrer, G | 1 |
| Chen, SN; Hoffman, MZ | 1 |
| Jordan, RB; Letter, JE | 1 |
| Butler, AP; Revzin, A; von Hippel, PH | 1 |
| Umbarger, HE | 1 |
| Dallocchio, F; Rippa, M; Signorini, M | 1 |
| Carlson, GM; Colombo, G; Lardy, HA | 1 |
| Kawada, S; Nakashima, Y; Sanada, H; Suzue, R | 2 |
| Herron, MJ; Nelson, RD; Schmidtke, JR; Simmons, RL | 1 |
| Giartosio, A; Riva, F; Turano, C | 1 |
| David, JC | 1 |
| Yamamoto, O | 1 |
| Kulbe, KD; Nogueira-Hattesohl, YM | 1 |
| Kochkina, VM; Torchinskii, YM | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Hewitt, JA; Kilmartin, JV; Wootton, JF | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Larsson, LE; Melin, P; Ragnarsson, U | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| Heinrich, D; Kubli, F; Metz, J; Wesch, H | 1 |
| Barbacid, M; Jing, S; Tapley, P | 1 |
| Canessa, CM; Horisberger, JD; Louvard, D; Rossier, BC | 1 |
| Lukas, TJ; Staros, JV; Woltjer, RL | 1 |
| Atrian, S; Gonzàlez-Duarte, R; Jörnvall, H; Krook, M; Prozorovski, V | 1 |
| Harada, I; Takeuchi, H; Yoshida, H | 1 |
| Feinberg, BA; Harder, SR; Nettesheim, DG; Otvos, JD | 1 |
| Jimbow, K; Pankovich, JM | 1 |
| Fujimoto, H; Haneda, M; Nakatsuka, M; Nisimoto, Y; Nomura, S; Ohta, T; Shibata, Y; Takeuchi, F; Tamai, T; Tsubouchi, R | 1 |
| Caine, JM; McLeish, MJ | 1 |
| Matsumoto, H; Mori, S | 1 |
| Hunziker, PE; Kojima, Y | 1 |
| Dulik, DM; Hayden, PJ; McCann, DJ; Stevens, JL; Ward, AJ; Yang, Y | 1 |
| Del Boccio, G; Federici, G; Lo Bello, M; Pennelli, A; Petruzzelli, R; Ricci, G; Whitehead, EP | 1 |
| Brinck, C; Carstam, R; Hindemith-Augustsson, A; Rorsman, H; Rosengren, E | 1 |
| Adachi, S; Ishimori, K; Morishima, I; Nagano, S; Watanabe, Y | 1 |
| Miki, M | 1 |
| D'Alessandro, AM; D'Andrea, G; Franceschini, N; Maurizi, G; Oratore, A; Perilli, G; Van Beeumen, J | 1 |
| Bass, SH; Mulkerrin, MG; Wells, JA | 1 |
| el-Sayed, MA; Gobind Khorana, H; Jang, DJ; Marti, T; Mogi, T; Wu, SG | 1 |
| Arisaka, F; Ishii, S; Kyogoku, Y; Takeda, S | 1 |
| Tarui, S; Uemichi, T; Ueno, S; Yorifuji, S | 1 |
| Burtnick, LD; Clark, ID | 1 |
| Alvarez, E; Davis, RJ; Gironès, N | 1 |
| Bray, MR; Clarke, AJ | 1 |
| Jauch, A; Lutz, WK | 1 |
| Asano, T; Honda, S; Kajio, T; Nishimura, O | 1 |
| Ekman, L; Magnusson, I; Wahren, J; Wångdahl, M | 1 |
| Beale, D; Coadwell, J | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Douglas, KT; John, DC | 1 |
| Grant, D; Long, WF; Williamson, FB | 1 |
| Chapman, D; Herzyk, E; Owen, JS | 1 |
| de Graaf, FK; Jacobs, AA; van Mechelen, JR | 1 |
| Axelrod, B; Crivellone, MD; Hermodson, M | 1 |
| Lefkowitz, RJ; Nakata, H; Regan, JW | 1 |
| Feller, A; Rudman, D | 1 |
| Pumphrey, JG; Rudikoff, S | 1 |
| Gilles, P; Keudell, KC; Robertson, NL | 1 |
| Ament, ME; Dell, RB; Greene, HL; Heird, WC; Helms, RA; Karna, P; Storm, MC | 1 |
| Dell, RB; Hay, W; Heird, WC; Helms, RA; Kashyap, S; Storm, MC | 1 |
| Bivins, B; Bradford, RR; Day, AT; Gazzaniga, AB; Steiger, E; Vanderhoof, JA; Waxman, K | 1 |
| Chakrabarti, B; Mandal, K | 1 |
| Kiick, DM; Phillips, RS | 1 |
| Maley, F; Maley, GF | 1 |
| Gallin, JI; Nath, J | 1 |
| Botstein, D; Fitts, R; Mulholland, J; Reuveny, Z; van Amsterdam, J | 1 |
| Kustrzeba-Wójcicka, I; Pietkiewicz, J; Wolna, E; Wolny, M | 1 |
| Butler, J; Land, EJ; Prütz, WA; Swallow, AJ | 1 |
| Keller, JM; Keller, KM | 1 |
| Barden, JA; dos Remedios, CG | 1 |
| Schafer, R; Tedesco, JL | 1 |
| Rudman, D; Williams, PJ | 1 |
| Anderson, RG; Brown, MS; Davis, CG; Goldstein, JL; Lehrman, MA; Russell, DW | 1 |
| Rorsman, H; Rosengren, AM; Rosengren, E | 2 |
| Everett, MM; Miller, WA | 3 |
| Colman, RF | 1 |
| Reynolds, RD; Thompson, SD | 1 |
| Kagamiyama, H; Matsubara, H; Shin, M; Wada, K | 1 |
| Doolittle, RF; Metzger, H; Singer, SJ | 1 |
| Habeeb, AJ; Hiramoto, R | 1 |
| Bradbury, JH; Chapman, GV | 1 |
| Marinetti, GV; Pettit, D | 1 |
| Armstrong, FB; Harper, RA | 2 |
| Ellis, HK; Watkins, WB | 1 |
| Eller, PM; Finelli, VN; Montague, PJ; Petering, HG | 1 |
| Castrup, HJ; Klein, HO | 1 |
| Lukasiewicz, H; Niewiarowski, S | 1 |
| Hegyi, G; Horányi, M; Mühlrad, A | 1 |
| Oe, M; Seon, BK; Titani, K; Tonomura, Y | 1 |
| Bertolini, R; Gabler, W; Pabst, R | 1 |
| Dudrick, SJ; Ruberg, RL; Schlappner, OL; Shelley, WB | 1 |
| Bailin, G; Bárány, M | 2 |
| Senior, AE | 1 |
| Aĭzenberg NN+AIZENBERG, NN; Korabel'shchikova, NI; Lesik, OV | 1 |
| Donnell, GN; Koch, R; Lieberman, E; Shaw, KN | 1 |
| Hirsh, DI; Lipmann, F | 1 |
| Bailin, G; Bárány, K; Bárány, M | 1 |
| Calabrese, L; Rotilio, G | 1 |
| Ellison, JS; Siegel, L | 1 |
| Karadźić, V; Micić, D; Rakić, L | 1 |
| Nicholls, CH; Pailthorpe, MT | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Litwack, G; Miller, JE | 1 |
| de Bruin, SH; Janssen, LH; van Os, GA; Willekens, FL | 1 |
| Harris, R; Sellinger, OZ; Water, R; Zand, R | 1 |
| Huestis, WH; Raftery, MA | 1 |
| Amons, R; Groene, A; Möller, W; Terhorst, C | 1 |
| Horecker, BL; Lai, CY | 1 |
| Frimpter, GW | 1 |
| Bhattacharya, RK | 1 |
| Lemieux, G | 1 |
| Fellman, JH; Fujita, TS; Roth, ES | 1 |
| Arai, T; Mikami, Y | 1 |
| Deutsch, HF; Lin, KT | 1 |
| Booth, EM; Mallick, NP; Milewczyk, BK; Robins, AJ | 1 |
| Burstein, Y; Patchornik, A | 1 |
| Bradbury, JH; Ley, KF | 1 |
| Good, RA; Jose, DG | 1 |
| Bocharov, AL; Demidkina, TV; Karpeisky, MY; Polyanovsky, OL | 1 |
| Digendra, V; Mukherjee, PP; Mukherjee, S | 1 |
| Akimoto, H; Ho, R; Price, CC | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Liao, TH; Moore, S; Salnikow, J; Stein, WH | 1 |
| Birchmeier, W; Christen, P; Zaoralek, PE | 1 |
| Bacon, VA; Duffield, AM; Hoyano, Y; Pereira, WE; Summons, RE | 1 |
| Van Heyningen, R | 1 |
| Biszku, E; Sajgó, M; Solti, M; Szabolcsi, G | 1 |
| Barth, RF; Dunn, DR | 1 |
| Fridkin, M; Goren, HJ | 1 |
| Kirschenbaum, DM | 1 |
| Koch, GL | 1 |
| Azuma, K; Azuma, M; Kito, Y | 1 |
| Bahadur, K; Singh, YP; Verma, ML | 1 |
| Bocharov, AL; Demidkina, TV; Karpeiskii, MY; Polyanovskii, OL | 1 |
| Horecker, BL; Morse, DE | 1 |
| Singer, SJ | 1 |
| Maldyk, E | 1 |
| Kumagai, H; Matsui, H; Ogata, K; Ohkishi, H; Yamada, H | 1 |
| Flesch, P | 1 |
| Biserte, G | 1 |
| Stark, GR | 1 |
| Adams, CW | 1 |
| Jörnvall, H | 1 |
| Morenkova, SA | 1 |
| Paulus, H; Thorner, JW | 1 |
| Staehelin, M; Wehrli, W | 1 |
| Anderson, B; Kundig, W; Roseman, S; Weigel, N | 1 |
| Fimian, WJ; Graziadei, WD; Plocke, DJ | 1 |
| Prescott, JM; Wagner, FW | 1 |
| de Moraes, FF; Kulay, L | 1 |
| Demopoulos, HB; Duke, PS; Yuen, TG | 1 |
| Pirie, A | 1 |
| Irimajiri, T; Itakura, H; Seiji, M; Yoshida, T | 1 |
| Jesensky, C; Peterkofsky, A | 1 |
| Demopoulos, HB; Hourani, BT | 1 |
| Calissano, P; Friesen, A; Moore, BW | 1 |
| Beaman, TC; Gerhardt, P; Matz, LL | 1 |
| Abel, CA; Grey, HM; Prahl, JW | 1 |
| Prabhakaran, K | 1 |
| Nagai, M; Sugita, Y; Yoneyama, Y | 1 |
| Salhany, JM | 1 |
| Jacobsen, C | 1 |
| Adams, GE; Aldrich, JE; Bisby, RH; Cundall, RB; Redpath, JL; Willson, RL | 1 |
| Harris, C; Metzler, DE; Siano, D; Thomson, JA; Yang, IY | 1 |
| Holt, LA; Milligan, B | 1 |
| Cebra, JJ; Ray, A | 1 |
| Ruckhäberle, KE; Viehweg, B; Wolff, C | 2 |
| Shepherd, SL; Wagner, FW | 1 |
| Buchwald, BM | 1 |
| Shall, S; Waheed, A | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Fishman, WH; Sie, HG | 1 |
| Cavins, JF; Kwolek, WF | 1 |
| Kearney, EB; Seng, R; Singer, TP; Walker, WH | 1 |
| Churchich, JE; Wampler, J | 1 |
| Hiyama, T; Ishida, Y; Onishi, M; Yabuuchi, Y | 1 |
| Barra, D; Bossa, F; Ferraro, A; Giartosio, A; Turano, C | 1 |
| Notides, AC; Williams-Ashman, HG | 1 |
| Adamson, J; Hayashi, A; Stamatoyannopoulos, G; Yoshida, A | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
| Butt, WR | 1 |
| Grävinghoff, J; Hanson, H | 1 |
| Ghiara, G; Misuraca, G; Nicolaus, RA; Prota, G | 1 |
| Hoshino, S; Tsubota, H | 1 |
| Bertelsen, TI; Ehlers, N | 1 |
| Galiazzo, G; Jori, G; Scoffone, E | 1 |
| Steiner, RF; Weinryb, I | 1 |
| Bolinder, AE | 1 |
| Klotz, IM; Rill, RL | 1 |
| Blackburn, MN; Chatterjee, GC; Noltmann, EA; Pon, NG; Schnackerz, KD | 1 |
| Lingens, F; Sprössler, B | 1 |
| Carraway, KL; Triplett, RB | 1 |
| Neuhoff, V; Weise, M | 1 |
| de Repentigny, J; Matheieu, LG; Trudeau, T | 1 |
| A'zary, EP; Bigelow, CC | 1 |
| Melcher, G | 1 |
| Pradel, LA; Roustan, C | 1 |
| Hampton, JR | 1 |
| Damoglou, AP; Lindley, H; Stapleton, IW | 1 |
| Galiazzo, G; Jori, G; Marchiori, F; Scoffone, E | 1 |
| Huc, C; Olomucki, A | 1 |
| Ellfolk, N | 1 |
| Ansorge, S; Bohley, P | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Du Vigneaud, V; Yamashiro, D | 1 |
| Bachmayer, H; Mayhew, S; Peel, JL; Yasunobu, KT | 1 |
| Adams, CW; Bayiss, OB | 1 |
| Brown, JH; Mackey, HK | 1 |
| Chou, C; Larin, FF; Rose, CM; Wurtman, RJ | 1 |
| Manahan, J; Mandl, I | 1 |
| Steenbergen, ST; Weinberg, ED | 1 |
| Meun, DH; Smith, KC | 1 |
| Konikova, AS; Kritzman, MG; Morenkova, SA | 2 |
| Smith, KC | 1 |
| Gorbunoff, MJ; Herskovits, TT; Timasheff, SN; Townend, R | 1 |
| Fondy, TP; Ross, CR; Sollohub, SJ | 1 |
| Bayfield, RF; Cole, ER | 1 |
| Beyer, H; Schenk, U | 1 |
| Stadler, DR | 1 |
| Ebata, M; Otsuka, H; Takahashi, Y | 1 |
| Blum, JJ; Owens, I | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Efron, ML; Mechanic, GL; Shih, VE | 1 |
| Shaltiel, S | 1 |
| Agrup, G; Rorsman, H; Rosengren, E | 1 |
| Fujita, K; Ito, S; Jimbow, K; Kato, T; Kiyota, M | 1 |
| Jergil, B; Lindbladh, C; Rorsman, H; Rosengren, E | 1 |
| Folkers, K; Lutz, WB | 1 |
| Chantler, C; Dalton, RN | 1 |
| Ghadimi, H | 1 |
| Chang, XJ; Hsu, WS; Hsu, WT; Shih, TS; Yang, CC | 1 |
| Prota, G | 1 |
| Ichihashi, M; Mishima, Y; Mojamdar, M | 1 |
| Agrup, G; Hansson, C; Rorsman, H; Rosengren, E | 1 |
| Abu El Failat, RR; Davies, JV; Moore, JS | 1 |
| Birnbaum, ER; Darnall, DW; Hagag, N | 1 |
| Elliott, JI; Ljungdahl, LG | 1 |
| Gillespie, JM; Marshall, RC; Moore, GP; Panaretto, BA; Robertson, DM | 1 |
| Annamalai, AE; Colman, RF | 1 |
| Brabec, V; Mornstein, V | 1 |
| Kim, PS; Lumb, KJ | 1 |
| Lee, ES; Lin, R; Steiner, M | 1 |
| Abboud, HE; Biswas, P; Choudhury, GG; Grandaliano, G | 1 |
| Holmberg, L; Kornfält, R; Kristoffersson, AC; Schaedel, C | 1 |
| Ford, CE; Furlong, MT; Geahlen, RL; Harrison, ML | 1 |
| Wang, YD; Wong, K; Wood, WI | 1 |
| Stauffacher, CV; Van Etten, RL; Zhang, M | 1 |
| Chen, HY; Demidkina, TV; Phillips, RS | 1 |
| Gonnelli, M; Strambini, GB | 1 |
| Arai, K; Chrousos, GP; DiGeorge, AM; Latronico, AC; Rapaport, R; Tsigos, C | 1 |
| Barry, PH; Cunningham, AM; French, PW; Pierce, KD; Rajendra, S; Schofield, PR; Vandenberg, RJ | 1 |
| Itoh, K; Kuroki, Y; Nadaoka, Y; Sakuraba, H; Tanaka, T | 1 |
| Kim, YT; Muramatsu, T; Takahashi, K | 1 |
| Iida, M; Imanaka, T; Ito, K; Jinnouchi, H; Kamohara, S; Kan, M; Kanai, F; Nishioka, Y; Ohnishi, T; Todaka, M | 1 |
| Barghini, I; Camici, G; Cappugi, G; Caselli, A; Chiarugi, P; Cirri, P; Manao, G; Pazzagli, L; Ramponi, G; Raugei, G | 1 |
| Decker, SJ; Dobrusin, EM; MacLean, D; McNamara, DJ; Milarski, KL; Pearl, CG; Sawyer, T; Thieme-Sefler, A; Zhang, ZY; Zhu, G | 1 |
| Chan, RM; Crabb, DW; Harris, RA; Hawes, JW; Rougraff, PM | 1 |
| Richards, JE; Scott, KM; Sieving, PA | 1 |
| Fontecave, M; Henry, Y; Lepoivre, M; Roy, B | 1 |
| al-Mehdi, AB; Ischiropoulos, H | 1 |
| Offer, G; Sessions, R | 1 |
| Beaudet, A; Botto, JM; Chabry, J; Mazella, J; Nouel, D; Vincent, JP | 1 |
| Miura, T; Thomas, GJ | 1 |
| Barone, V; Ceccherini, I; Loviselli, A; Martino, E; Pacini, F; Pinchera, A; Romei, C; Romeo, G | 1 |
| Charlesworth, P; Dubbelman, TM; Lagerberg, JW; Truscott, TG; VanSteveninck, J | 1 |
| Eckstein, JW; Finer-Moore, J; Foster, PG; Santi, DV; Wataya, Y | 1 |
| Chuang, DT; Chuang, JL; Cox, RP; Fisher, CR | 1 |
| Bianchi, F; Hublau, P; Rousseaux, J; Rousseaux-Prevost, R | 1 |
| Evangelatos, GP; Ithakissios, DS; Kakabakos, SE; Tyllianakis, PE | 1 |
| Amano, T; Kaibara, C; Matsui, T; Muneyuki, E; Odaka, M; Ogasahara, K; Yoshida, M; Yutani, K | 1 |
| Fuchs, JA; Hanson, C; Li, H; Thomas, GJ; Woodward, C | 1 |
| Ishizaki, K; Kato, MV; Saijo, M; Sasaki, MS; Taya, Y | 1 |
| Pawlowski, JE; Penning, TM | 1 |
| Arola, LI; Salvadó, MJ | 1 |
| Cross, CE; Halliwell, B; Hu, ML; Kaur, H; Louie, S; O'Neill, CA; van der Vliet, A | 1 |
| Ator, M; Bollinger, JM; McCraken, J; Peisach, J; Robins, MJ; Salowe, S; Samano, MC; Stubbe, J | 1 |
| Auld, DS; Betz, SF; Doyle, DF; Pielak, GJ; Saunders, AJ; Young, GB | 1 |
| Berntorp, E; Dahlbäck, B; Donnér, M; Holmberg, L; Kristoffersson, AC; Nilsson, IM; Scheibel, E; Thorsen, S | 1 |
| Adachi, S; Egawa, T; Ishimori, K; Kitagawa, T; Makino, R; Morishima, I; Nagano, S; Watanabe, Y | 1 |
| Fogarty, KW; Nhamburo, P; Simpkins, CO | 1 |
| Blow, DM; Collyer, C; Cui, T; Goldberg, J; Hartley, BS; Rangarajan, M; Varsani, L | 1 |
| Cox, JA; Durussel, I; Rhyner, JA; Strehler, EE | 1 |
| Reichard, P | 1 |
| Célerier, J; Clauser, E; Cohen, P; Corvol, P; Gimenez-Roqueplo, AP; Guyene, TT; Jeunemaitre, X; Leconte, I; Pau, B; Simon, D | 1 |
| Lee, EY; Long, F; Zhang, L; Zhang, Z | 1 |
| Ceccherini, I; Elisei, R; Mancusi, F; Martino, E; Molinaro, E; Pacini, F; Pinchera, A; Romei, C; Romeo, G | 1 |
| Benditt, M; Christner, P; Jimenez, SA; Yankowski, RL | 1 |
| Morrison, P; Rosner, MR; Saltiel, AR | 1 |
| Bonaventure, J; Freisinger, P; Nerlich, AG | 1 |
| Nakashima, I | 1 |
| Amann, T; Apfelstedt-Sylla, E; Felbor, U; Schönherr, U; Stöhr, H; Weber, BH | 1 |
| Guyer, CA; Staros, JV; Tong, K | 1 |
| Bonfoco, E; Leist, M; Lipton, SA; Nicotera, P; Orrenius, S; Zhivotovsky, B | 1 |
| Swift, JA | 1 |
| Fujii, T; Fujimoto, T; Fujimura, K; Katsutani, S; Kuramoto, A; Matsuzaki, M; Mochizuki, T; Noda, M; Sano, M; Shimomura, T; Takafuta, T; Yamazaki, T | 1 |
| Peter-Katalinić, J; Rizner, TL; Strupat, K; Zakelj-Mavric, M; Zorko, M | 1 |
| Andersson, C; Bergman, T; Ekström, L; Morgenstern, R; Raza, H; Weinander, R | 1 |
| Camaschella, C; Carella, M; D'Ambrosio, L; Franco, B; Gasparini, P; Girelli, D; Grifa, A; Piperno, A; Roetto, A; Totaro, A; Valentino, MA | 1 |
| Smith, BJ; Tempst, P | 1 |
| Bannister, JV; Bannister, WH; Hunter, GJ; Hunter, T; Ikebukuro, K | 1 |
| Chang, JG; Lin, SF; Liu, TC | 1 |
| Bertina, RM; Landolfi, R; Poort, SR | 1 |
| Agner, E; Engebretsen, M; Fischer, PM; Sandosham, J | 1 |
| Hazeki, O; Hoshino, S; Inoue, S; Kanda, Y; Katada, T; Kishimoto, H; Kontani, K; Kukimoto, I; Nishina, H; Takahashi, K | 1 |
| Acton, RT; Barton, JC; Harmon, L; Rivers, C; Rothenberg, BE; Sawada-Hirai, R; Shih, WW | 1 |
| Harashima, S; Mukai, Y; Ohno-Yamashita, Y; Oshima, Y | 1 |
| Gogia, R; Richer, SP; Rose, RC | 2 |
| Muneyuki, E; Odaka, M; Yoshida, M | 1 |
| Costa, T; Erlacher, L; Kilpatrick, MW; Lembessis, P; Lin, K; Luyten, FP; Thomas, JT; Tsipouras, P | 1 |
| Cox, TM; Raha-Chowdhury, R; Rhodes, DA; Trowsdale, J | 1 |
| Chen, JG; Rudnick, G; Sachpatzidis, A | 1 |
| Johnson, WC; Krittanai, C | 1 |
| Ishiguro, I; Ito, S; Ozeki, H; Wakamatsu, K | 1 |
| Aslam, S; Standen, GR | 1 |
| Dougherty, DA; Gallivan, JP; Lester, HA | 1 |
| Koerten, HK; Kolb, RM; Lentjes, EG; Mommaas, AM; Pavel, S; Smit, NP; Van der Meulen, H | 1 |
| Burt, MJ; Chapman, BA; Faed, JM; George, PM; Morison, IM; Upton, JD | 1 |
| Petersen, BO; Shuman, S; Wittschieben, J | 1 |
| Bagley, CJ; Lopez, AF; Stomski, FC; Sun, Q; Woodcock, JM; Zacharakis, B | 1 |
| Allison, WS; Dou, C; Grodsky, NB | 1 |
| Crow, JP; MacMillan-Crow, LA; Thompson, JA | 1 |
| Devay, P; Kuo, Y; Role, L; Yang, X; Yu, C | 1 |
| Smillie, D | 1 |
| Komath, SS; Nadimpalli, SK; Swamy, MJ | 1 |
| Ikebukuro, K; Karube, I; Watanabe, A; Yano, K | 1 |
| Gao, J; Qin, Z; Schöneich, C; Squier, TC; Sun, H; Williams, TD; Yao, Y; Yin, DH | 1 |
| Chater, K; Damji, F; Elliot, M; Leskiw, B; Passantino, R | 1 |
| Gottschalk, R; Hoelzer, D; Kaltwasser, JP; Löffler, T; Seidl, C; Seifried, E | 1 |
| Busch, R; Doebele, RC; Fahrni, J; Mellins, ED; von Scheven, E | 1 |
| Kordowska, J; Stafford, WF; Wang, CL | 1 |
| Jimbow, K | 1 |
| Katagiri, Y; Nakamura, M; Nakashima, S; Nozawa, Y | 1 |
| Airaud, F; Andre, MT; Benichou, B; Herbert, O; Jacquemont, S; Moisan, JP; Raguenes, O; Renault, S | 1 |
| Itoh, K; Miharu, N; Mizoguchi, N; Ohama, K; Sakuraba, H; Shimmoto, M; Utsumi, K | 1 |
| Ellard, S; Frayling, T; Grove, J; Hattersley, AT; Walker, M | 1 |
| Kotovych, G; McClung, RE; Nakashima, TT | 1 |
| Atkinson, TP; Volanakis, JE; Zhu, ZB | 1 |
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| Cao, J; Olsen, BD; Seifried, BM | 1 |
| Gray, HB; Winkler, JR | 1 |
| Azevedo Pereira, B; Betarelli, RP; Castillo-Martín, M; Estrada, E; Fernández-Novell, JM; Peña, A; Placci, A; Rocco, M; Rodríguez-Gil, JE; Yeste, M; Zangeronimo, MG | 1 |
| Aleksandrova, AA; Forrest, LR; Rudnick, G; Sinning, S; Tavoulari, S; Zhang, YW | 1 |
| Cai, W; Cao, W; Dai, Z; Hu, L; Huang, Y; Liu, T; Qin, X; Tang, H; Wang, C; Yang, F | 1 |
| Deng, L; Kong, Y; Lei, Z; Li, H; Tan, W; Wu, D | 1 |
| Bartesaghi, S; Estrin, DA; Pedron, FN; Radi, R; Zeida, A | 1 |
| Lin, PY; Yang, KL | 1 |
| Davis, I; Koto, T; Li, J; Liu, A | 1 |
| Bou-Nader, C; Dozova, N; Hamdane, D; Lacombat, F; Plaza, P | 1 |
| Costa-Broseta, Á; León, J | 1 |
| Dey, M; Nandi, S; Srivastava, D | 1 |
| Sato, S | 1 |
| Bernardino, SJ; Harran, PG; Jones, CG; Mendoza, A; Tsunemi, T | 1 |
| Gong, H; Hickford, JGH; Li, S; Luo, Y; Wang, J; Zhou, H | 1 |
| Ávila, F; Dorta, E; Fuentealba, D; Fuentes-Lemus, E; López-Alarcón, C | 1 |
| Aguirre, P; Aspée, A; Barrias, P; Castro-Fernandez, V; Fuentes-Lemus, E; Guixé, V; Herrera-Morande, A; López-Alarcón, C; Mura, F; Rivas-Aravena, A; Rojas, T; Zamora, RA | 1 |
| DeRouchey, JE; Kirchoff, DC; Moseley, HNB; Powell, CD | 1 |
| Lund, MN; Poojary, MM; Skibsted, LH; Zhao, Z | 1 |
| Alvarez Dorta, D; Deniaud, D; Gouin, SG; Mével, M | 1 |
| Ahmady, IM; Hameed, MK; Han, C; Mohamed, AA | 1 |
| Borgaonkar, M; Lim, DR; Phua, C; Vidyasankar, G | 1 |
| De Loose, PJ; De Smedt, S; Michiels, J; Vercauteren, S; Verstraeten, N; Wilmaerts, D | 1 |
| He, Y; Kong, H; Liu, X; Sun, X; Wang, N; Yang, H | 1 |
| Flashman, E; Gunawardana, DM; Heathcote, KC | 1 |
| Garg, G; Rizvi, SI; Singh, AK; Singh, S; Verma, AK | 1 |
| Andrási, D; Matejka, J; Nyíri, K; Ozohanics, O; Szabó, JE; Vértessy, B | 1 |
| Bingman, CA; Brunold, TC; Elmendorf, LD; Fernandez, RL; Fox, BG; Smith, RW | 1 |
| Davies, MJ; Fuentes-Lemus, E; Rossi, C | 1 |
| Hammes-Schiffer, S; Reinhardt, CR; Zhong, J | 1 |
| Medvedeva, MV; Muronetz, VI; Pozdyshev, DV; Sevostyanova, IA | 1 |
| Blasco, P; Feng, H; Fung, YME; Jiang, H; Jiang, T; Li, X; Li, Y; Pu, F; Wang, C; Yu, R; Zhang, Q; Zhang, Y; Zhong, Z | 1 |
| Anjum Zia, M; Jahan, N; Kiran, S; Mujtaba, N; Naqvi, SAR; Sultana, B | 1 |
| Hammes-Schiffer, S; Konstantinovsky, D; Reinhardt, CR; Soudackov, AV | 1 |
| Gothelf, KV; Kjaersgaard, NL; Nielsen, TB | 1 |
| Berthelet, J; Bui, LC; Chevreux, G; Deshayes, F; Dupret, JM; Gou, P; Legros, V; Liu, R; Moroy, G; Nian, Q; Rodrigues Lima, F; Wang, L; Zhang, W | 1 |
| Dietz, KJ; García-Caparrós, P; Kumar, V; Persicke, M; Vogelsang, L; Wirtz, M | 1 |
| Andrés Juan, C; Andrés, CMC; Pérez de la Lastra, JM; Pérez-Lebeña, E; Plou, FJ | 1 |
| Davies, MJ; Doblas, L; Fuentes-Lemus, E; Hägglund, PM | 1 |
| Anzaki, K; Denda, M; Harada, N; Inagaki, N; Kobayashi, D; Kyan, R; Ohkawachi, K; Otaka, A; Shigenaga, A; Yasuda, T | 1 |
| Che, L; Fang, Z; Feng, B; Hua, L; Jiang, X; Li, J; Lin, Y; Sun, M; Wang, Y; Xu, S; Zhuo, Y; Zou, X | 1 |
| Bowers, AA; Bowler, MM; Fleming, MC; Park, R; Popov, KI | 1 |
| Brunold, TC; Fox, BG; Sabat, G; Schultz, RL | 1 |
49 review(s) available for tyrosine and cysteine
| Article | Year |
|---|---|
Chemical strategy for studying the antigenic structures of disulfide-containing proteins: hen egg-white lysozyme as a model.
Topics: Amino Acid Sequence; Antibodies; Arginine; Cysteine; Disulfides; Epitopes; Hydrogen-Ion Concentration; Kinetics; Methanol; Methionine; Models, Molecular; Muramidase; Myoglobin; Optical Rotatory Dispersion; Peptide Fragments; Precipitin Tests; Protein Conformation; Tryptophan; Tyrosine | 1977 |
Amino acid biosynthesis and its regulation.
Topics: Amino Acids; Arginine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Histidine; Phenylalanine; Pyruvates; Serine; Tyrosine | 1978 |
Effect of vitamin C on tubulin tyrosinolation in polymorphonuclear leukocytes.
Topics: Ascorbic Acid; Chediak-Higashi Syndrome; Cysteine; Dithiothreitol; Glutathione; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Protein Processing, Post-Translational; Tubulin; Tyrosine | 1987 |
Nutrient deficiencies during total parenteral nutrition.
Topics: Adolescent; Adult; Aged; Animals; Biotin; Carnitine; Child; Choline Deficiency; Chromium; Copper; Cysteine; Deficiency Diseases; Dogs; Fatty Acids, Essential; Female; Folic Acid Deficiency; Guinea Pigs; Humans; Infant; Male; Middle Aged; Molybdenum; Parenteral Nutrition; Parenteral Nutrition, Total; Phosphates; Rats; Selenium; Sheep; Taurine; Tyrosine; Vitamin A Deficiency; Zinc | 1985 |
Aldolase: a model for enzyme structure-function relationships.
Topics: Age Factors; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Crystallization; Cyanogen Bromide; Cysteine; Fructose-Bisphosphate Aldolase; Histidine; Isoenzymes; Lysine; Macromolecular Substances; Models, Chemical; Muscles; Plants; Rabbits; Saccharomyces cerevisiae; Schiff Bases; Species Specificity; Structure-Activity Relationship; Tyrosine | 1972 |
Aminoacidurias due to inherited disorders of metabolism (first of two parts).
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Cystathionine; Cysteine; Cystine; Disulfides; Female; Homocystinuria; Humans; Infant, Newborn; Lactates; Male; Methionine; Oxidoreductases; Phenylalanine; Phenylketonurias; Pregnancy; Pyruvates; Sulfhydryl Compounds; Sulfites; Sulfur; Tyrosine | 1973 |
The mechanism of action of aldolases.
Topics: Amino Acid Sequence; Animals; Bacteria; Binding Sites; Biological Evolution; Carbohydrate Metabolism, Inborn Errors; Cattle; Chelating Agents; Chemistry, Organic; Cysteine; Fructose; Fructose-Bisphosphate Aldolase; Genetics; Histidine; Liver; Lysine; Metals; Models, Chemical; Molecular Weight; Muscles; Organ Specificity; Organic Chemistry Phenomena; Phosphates; Rabbits; Rats; Saccharomyces; Tyrosine | 1968 |
Covalent labeling of active sites.
Topics: Amino Acid Sequence; Amino Acids; Antibodies; Binding Sites; Carbon Isotopes; Chymotrypsin; Cysteine; Haptens; Histidine; Isoflurophate; Lysine; Models, Chemical; Phosphoglucomutase; Proteins; Trypsin; Tryptophan; Tyrosine | 1967 |
[Structure and origin of fibrinoid].
Topics: Collagen Diseases; Cysteine; Extracellular Space; Fibrin; Humans; Rheumatoid Nodule; Shwartzman Phenomenon; Tryptophan; Tyrosine | 1969 |
Studies of the red pigmentary system.
Topics: Amino Acids; Animals; Biological Evolution; Chemical Phenomena; Chemistry; Chickens; Chromatophores; Cricetinae; Cysteine; Feathers; Hair; Humans; Iron; Molecular Weight; Peptides; Pigmentation; Pigments, Biological; Rabbits; Species Specificity; Terminology as Topic; Tyrosine | 1970 |
[Structural data on lactate dehydrogenase isoenzymes].
Topics: Amino Acids; Animals; Binding Sites; Cattle; Coenzymes; Cysteine; Electrophoresis; Embryo, Mammalian; Histidine; Humans; Hybridization, Genetic; Hydrogen; Isoenzymes; L-Lactate Dehydrogenase; Male; Molecular Weight; Peptides; Rabbits; Rats; Spermatozoa; Testis; Tyrosine | 1970 |
Recent developments in chemical modification and sequential degradation of proteins.
Topics: Amines; Arginine; Chemical Phenomena; Chemistry; Cysteine; Histidine; Methionine; Proteins; Sulfhydryl Compounds; Sulfides; Tryptophan; Tyrosine | 1970 |
Growing points in cell pathology. Histochemical aspects.
Topics: Acid Phosphatase; Animals; Cholesterol; Cysteine; Enzymes; Esterases; Histocytochemistry; Humans; Indicators and Reagents; Lipids; Methods; Oxidoreductases; Phospholipids; Proteins; Triglycerides; Tryptophan; Tyrosine | 1970 |
Recent advances in the chemistry of melanogenesis in mammals.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Dihydroxyphenylalanine; Glutathione; Humans; Melanins; Melanocytes; Monophenol Monooxygenase; Pigmentation; Pigments, Biological; Thiazines; Tyrosine | 1980 |
Raman spectroscopy of proteins and their assemblies.
Topics: Animals; Cysteine; Humans; Peptides; Protein Biosynthesis; Protein Conformation; Proteins; Spectrum Analysis, Raman; Tyrosine | 1995 |
Can cysteine direct tyrosine in signal transduction for environment-oriented gene control?
Topics: Animals; Cysteine; Gene Expression Regulation; Humans; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Signal Transduction; Tyrosine | 1996 |
Morphology and histochemistry of human hair.
Topics: Carboxylic Acids; Cysteine; Cystine; Hair; Histocytochemistry; Humans; Mercury; Microscopy, Electron; Microscopy, Electron, Scanning; Phosphotungstic Acid; Silver; Staining and Labeling; Tyrosine; Uranium | 1997 |
Genetics of hemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Cloning, Molecular; Cysteine; Genes, MHC Class I; Genes, Recessive; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Iron; Membrane Proteins; Mutation, Missense; Tyrosine | 1999 |
[Diagnosis and treatment of primary hemochromatosis].
Topics: Cysteine; Female; Ferritins; Genetic Testing; Hemochromatosis; Homozygote; Humans; Liver Diseases; Liver Function Tests; Male; Mutation; Phlebotomy; Transferrin; Tyrosine | 1999 |
Current total parenteral nutrition solutions for the neonate are inadequate.
Topics: Amino Acids; Cysteine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intestine, Small; Methionine; Nutritional Requirements; Parenteral Nutrition, Total; Phenylalanine; Solutions; Tyrosine | 2000 |
Conditionally indispensable amino acids (glutamine, cyst(e)ine, tyrosine, arginine, ornithine, taurine) in enteral feeding and the dipeptide concept.
Topics: Amino Acids, Essential; Animals; Arginine; Cysteine; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Intestinal Mucosa; Ornithine; Taurine; Treatment Outcome; Tyrosine | 2000 |
Reactive nitrogen species and proteins: biological significance and clinical relevance.
Topics: Animals; Cysteine; Humans; Nitric Oxide; Proteins; Reactive Nitrogen Species; Tyrosine | 2001 |
Protein oxidation in aging and age-related diseases.
Topics: Aging; Amino Acids; Animals; Antioxidants; Apoptosis; Cross-Linking Reagents; Cysteine; Disease; Humans; Longevity; Methionine; Models, Biological; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptides; Peroxynitrous Acid; Protein Denaturation; Proteins; Rats; Reactive Oxygen Species; Tyrosine | 2001 |
Molecular analysis of hereditary deficiency of the third component of complement (C3) in two sisters.
Topics: Adolescent; Adult; Blotting, Western; Codon, Terminator; Complement C3; Cysteine; Female; Glycine; Homozygote; Humans; Lupus Erythematosus, Systemic; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tyrosine | 2001 |
Molecular anatomy of tyrosinase and its related proteins: beyond the histidine-bound metal catalytic center.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Catechol Oxidase; Cations; Copper; Cysteine; Glycosylation; Histidine; Melanins; Models, Biological; Models, Molecular; Molecular Sequence Data; Monophenol Monooxygenase; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tyrosine | 2002 |
Peroxynitrite activates kinases of the src family and upregulates tyrosine phosphorylation signaling.
Topics: Animals; Cysteine; Diffusion; Erythrocytes; Free Radicals; Humans; Models, Biological; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src Homology Domains; src-Family Kinases; Tyrosine; Up-Regulation | 2002 |
[From gene to disease; HFE-mutations in primary haemochromatosis].
Topics: Amino Acid Substitution; Cysteine; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Membrane Proteins; Mutation, Missense; Tyrosine | 2003 |
Redox proteomics: identification of oxidatively modified proteins.
Topics: Animals; Cysteine; Disulfides; Glutathione; Glutathione Reductase; Humans; Models, Biological; Models, Chemical; Oxidation-Reduction; Oxygen; Protein Processing, Post-Translational; Proteome; Reactive Nitrogen Species; Reactive Oxygen Species; Sulfhydryl Compounds; Tyrosine | 2003 |
Nano-tailoring; stitching alterations on viral coats.
Topics: Biocompatible Materials; Capsid Proteins; Cysteine; Lysine; Nanotechnology; Tyrosine; Viruses | 2004 |
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; Diagnosis, Differential; Hemochromatosis; Histidine; Humans; Hyperpigmentation; Iron Overload; Liver Cirrhosis; Liver Neoplasms; Mass Screening; Phlebotomy; Point Mutation; Population Surveillance; Prevalence; Prognosis; Tyrosine | 2004 |
Mitochondrial proteomics in free radical research.
Topics: Alcohols; Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Free Radicals; Humans; Mitochondria; Models, Biological; Nitrogen; Oxidative Stress; Oxygen; Protein Processing, Post-Translational; Proteome; Proteomics; Tyrosine | 2005 |
Peptidomics, current status.
Topics: Arginine; Chromatography, Affinity; Combinatorial Chemistry Techniques; Cysteine; Histidine; Humans; Lysine; Methionine; Peptides; Phosphotyrosine; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2005 |
Genetic predisposition to iron overload: prevalence and phenotypic expression of hemochromatosis-associated HFE-C282Y gene mutation.
Topics: Cysteine; Genetic Predisposition to Disease; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Iron Overload; Membrane Proteins; Mutation; Prevalence; Scandinavian and Nordic Countries; Tyrosine | 2006 |
Insights into von Willebrand factor proteolysis: clinical implications.
Topics: ABO Blood-Group System; ADAM Proteins; ADAMTS13 Protein; Amino Acids; Cysteine; Humans; Hydrolysis; Ligands; Models, Biological; Mutation; Polymorphism, Genetic; Purpura, Thrombotic Thrombocytopenic; Tyrosine; von Willebrand Diseases; von Willebrand Factor | 2006 |
Oxidative alterations of cyclooxygenase during atherogenesis.
Topics: Animals; Arachidonic Acid; Atherosclerosis; Cyclooxygenase Inhibitors; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Heme; Humans; Intramolecular Oxidoreductases; MAP Kinase Signaling System; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Tyrosine | 2006 |
Structure-activity relationships of urotensin II and URP.
Topics: Alanine; Amino Acid Sequence; Animals; Cysteine; Disulfides; Humans; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Peptide Hormones; Protein Conformation; Sequence Alignment; Structure-Activity Relationship; Tyrosine; Urotensins | 2008 |
[Structural modifications of proteins induced by nitric oxide].
Topics: Animals; Cysteine; Cytoplasm; Guanylate Cyclase; Humans; Nitrates; Nitric Oxide; Oxidative Stress; Plants; Proteins; Signal Transduction; Tyrosine | 2010 |
Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones.
Topics: Animals; Antioxidants; Catalysis; Cysteine; Disulfides; Humans; Hydrogen Peroxide; Kinetics; Molecular Chaperones; Oxidation-Reduction; Peroxides; Peroxiredoxins; Phosphorylation; Threonine; Tyrosine | 2011 |
eNOS activation and NO function: differential control of steroidogenesis by nitric oxide and its adaptation with hypoxia.
Topics: Adrenal Glands; Animals; Cyclic GMP; Cysteine; Enzyme Activation; Female; Guanylate Cyclase; Heme; Humans; Hypoxia; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type III; Ovary; Pregnancy; Protein Processing, Post-Translational; Steroids; Testis; Tyrosine | 2011 |
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine | 2011 |
The good and bad effects of cysteine S-nitrosylation and tyrosine nitration upon insulin exocytosis: a balancing act.
Topics: Apoptosis; Cyclic GMP; Cysteine; Diabetes Mellitus; Exocytosis; Female; Humans; Insulin-Secreting Cells; Male; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction; Tyrosine | 2012 |
Role of nitric oxide in the radiation-induced bystander effect.
Topics: Bystander Effect; Cell Transformation, Neoplastic; Cysteine; DNA Damage; Eukaryotic Cells; Gamma Rays; Genomic Instability; Humans; Mutagenesis; Neoplasm Proteins; Nitric Oxide; Protein Processing, Post-Translational; Reactive Nitrogen Species; Signal Transduction; Tyrosine | 2015 |
Present knowledge and controversies, deficiencies, and misconceptions on nitric oxide synthesis, sensing, and signaling in plants.
Topics: Cysteine; Nitric Oxide; Plant Development; Plant Growth Regulators; Plant Proteins; Plants; Protein Processing, Post-Translational; Signal Transduction; Stress, Physiological; Tyrosine | 2020 |
[Development and Application of Catalytic Tyrosine Chemical Modification].
Topics: Catalysis; Cysteine; Electron Transport; Electrons; Hemin; Luminol; Lysine; Oxidation-Reduction; Peroxidase; Proteins; Ruthenium; Tyrosine | 2019 |
Tyrosine Conjugation Methods for Protein Labelling.
Topics: Cysteine; Immunoconjugates; Lysine; Proteins; Staining and Labeling; Tyrosine | 2020 |
Emerging roles for thiol dioxygenases as oxygen sensors.
Topics: Arginine; Cysteamine; Cysteine; Cysteine Dioxygenase; Dioxygenases; Ferrous Compounds; Oxygen; Plants; Sulfhydryl Compounds; Tyrosine | 2022 |
Potential Effect of Post-Transcriptional Substitutions of Tyrosine for Cysteine Residues on Transformation of Amyloidogenic Proteins.
Topics: alpha-Synuclein; Amyloidogenic Proteins; Codon; Cysteine; Escherichia coli; Humans; Tyrosine | 2022 |
Chemical Conjugation to Less Targeted Proteinogenic Amino Acids.
Topics: Amines; Amino Acids; Cysteine; Lysine; Proteins; Tyrosine | 2022 |
Impact of Reactive Species on Amino Acids-Biological Relevance in Proteins and Induced Pathologies.
Topics: Amino Acids; Cysteine; Methionine; Proteins; Tryptophan; Tyrosine | 2022 |
3 trial(s) available for tyrosine and cysteine
| Article | Year |
|---|---|
Daily rhythms in the concentrations of various amino acids in human plasma.
Topics: Adolescent; Adult; Alanine; Amino Acids; Circadian Rhythm; Cysteine; Dietary Proteins; Glutamates; Glycine; Humans; Isoleucine; Male; Methionine; Phenylalanine; Tryptophan; Tyrosine | 1968 |
Metabolism of orally administered branched-chain alpha-keto acids.
Topics: Administration, Oral; Adult; Amino Acids, Branched-Chain; Amino Acids, Essential; Blood Glucose; Calcium; Cysteine; Female; Hemiterpenes; Humans; Insulin; Keto Acids; Male; Random Allocation; Time Factors; Tyrosine | 1983 |
Serum iron parameters, HFE C282Y genotype, and cognitive performance in older adults: results from the FACIT study.
Topics: Aged; Cognition; Cross-Sectional Studies; Cysteine; Double-Blind Method; Female; Ferritins; Folic Acid; Follow-Up Studies; Genotype; Hematinics; Hemochromatosis; Humans; Iron; Male; Middle Aged; Mutation; Tunica Intima; Tunica Media; Tyrosine | 2010 |
819 other study(ies) available for tyrosine and cysteine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Stabilization of rat liver tyrosine aminotransferase by tetracycline.
Topics: Adenosine Triphosphate; Animals; Cortisone; Cysteine; Enzyme Activation; Hydrocortisone; Liver; Lysosomes; Magnesium; Radioimmunoassay; Rats; Tetracycline; Tyrosine; Tyrosine Transaminase | 1975 |
Sulphr containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphide.
Topics: Amino Acids, Sulfur; Creatinine; Cysteine; Cystine; Dipeptides; Disulfides; Female; Homocysteine; Humans; Kidney Failure, Chronic; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Taurine; Tyrosine | 1979 |
Oxidizing action of purine N-oxide esters.
Topics: Acetylation; Acetylcysteine; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclic N-Oxides; Cysteine; Esters; Guanine; Hydrogen-Ion Concentration; Iodides; Iodine; Mercaptopurine; Methionine; Oxidation-Reduction; Purines; Pyridines; Sulfates; Sulfhydryl Compounds; Tryptophan; Tyrosine; Uric Acid; Xanthines | 1975 |
Effect of pH on the reactivity of the carbonate radical in aqueous solution.
Topics: Carbonates; Chymotrypsin; Cysteine; Histidine; Hydrogen-Ion Concentration; Methane; Methionine; Muramidase; Penicillamine; Photochemistry; Propionates; Ribonucleases; Solutions; Tyrosine; Water | 1975 |
Complexing of nickel(II) by cysteine, tyrosine, and related ligands and evidence for Zwitterion reactivity.
Topics: Binding Sites; Cysteine; Glutathione; Hydrogen-Ion Concentration; Kinetics; Ligands; Methionine; Methods; Nickel; Penicillamine; Tyrosine | 1975 |
Molecular parameters characterizing the interaction of Escherichia coli lac repressor with non-operator DNA and inducer.
Topics: Bacterial Proteins; Base Sequence; Circular Dichroism; Cysteine; DNA; Escherichia coli; Molecular Weight; Nucleic Acid Conformation; Protein Binding; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1977 |
Evidence for the proximity of a cysteinyl and a tyrosyl residue in the active site of 6-phosphogluconate dehydrogenase.
Topics: Binding Sites; Candida; Cysteine; Dansyl Compounds; Phosphogluconate Dehydrogenase; Sulfhydryl Compounds; Tyrosine | 1978 |
Phosphoenolpyruvate carboxykinase (guanosine triphosphate) from rat liver cytosol. Separation of homogeneous forms of the enzyme with high and low activity by chromatography on agarose-hexane-guanosine triphosphate.
Topics: Adenosine Triphosphate; Animals; Chromatography, Affinity; Cysteine; Cytosol; Dithionitrobenzoic Acid; Guanosine Triphosphate; Kinetics; Ligands; Liver; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Tryptophan; Tyrosine | 1978 |
Effect of catechol-thiol conjugates on tyrosinase-dependent tyrosine hydroxylation.
Topics: Basidiomycota; Catechol Oxidase; Catechols; Cysteine; Dose-Response Relationship, Drug; Glutathione; Hydroxylation; Monophenol Monooxygenase; Tyrosine | 1976 |
Chemiluminescence response of human leukocytes: influence of medium components on light production.
Topics: Culture Media; Cysteine; Dose-Response Relationship, Drug; Gelatin; Humans; Light; Luminescent Measurements; Neutrophils; Phagocytosis; Phenolsulfonphthalein; Tryptophan; Tyrosine; Zymosan | 1977 |
A pyridoxamine phosphate derivative.
Topics: Affinity Labels; Apoenzymes; Cysteine; Lysine; Methods; Organophosphorus Compounds; Protein Binding; Pyridoxamine; Spectrophotometry, Ultraviolet; Tyrosine | 1977 |
Evidence for the possible formation of a toxic tyrosine metabolite by the liver microsomal drug metabolizing system.
Topics: Animals; Benserazide; Biotransformation; Cobalt; Cysteine; Glutathione; Humans; Male; Maleates; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Proadifen; Tyrosine | 1976 |
American Academy of Pediatrics. Committee on Nutrition: special diets for infants with inborn errors of amino acid metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cysteine; Histidine; Homocystinuria; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Nutritional Requirements; Phenylalanine; Phenylketonurias; Risk; Tyrosine; Valine | 1976 |
Radiation-induced binding of some protein and nucleic acid constituents with macromolecular components in cell systems.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Cell Line; Cobalt Radioisotopes; Cysteine; Cystine; Cytosine; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Histidine; Leukemia, Lymphoid; Macromolecular Substances; Methionine; Mice; Phenylalanine; Protein Binding; Purines; Pyrimidines; Radiation Effects; Sulfur Radioisotopes; Thymine; Tritium; Tryptophan; Tyrosine; Uracil | 1975 |
Identification of subnanomole amounts of phenylthiohydantoins of the cysteine and methionine derivatives most commonly obtained in protein sequencing.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, Thin Layer; Cysteine; Hydantoins; Methionine; Methods; Microchemistry; Proteins; Thiohydantoins; Tyrosine | 1975 |
Reactivity of the cysteine and tyrosine residues of aspartate transaminase from chicken heart cytosol.
Topics: Animals; Aspartate Aminotransferases; Binding Sites; Chickens; Cysteine; Cytosol; Disulfides; Dithionitrobenzoic Acid; Ethylmaleimide; Iodoacetamide; Kinetics; Mercuribenzoates; Myocardium; Protein Binding; Pyridines; Sulfhydryl Compounds; Tetranitromethane; Tyrosine | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Alteration of functional properties associated with the change in quaternary structure in unliganded haemoglobin.
Topics: Arginine; Aspartic Acid; Binding Sites; Cysteine; Hemoglobins; Histidine; Humans; Ligands; Oxygen; Oxyhemoglobins; Phytic Acid; Protein Conformation; Structure-Activity Relationship; Sulfhydryl Compounds; Tyrosine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Synthesis of peptides by fragment condensation on a solid support. II. A scheme for preparation of 4,8-disubstituted vasopressins evaluated on 8-arginine-vasopressin.
Topics: Arginine Vasopressin; Asparagine; Cysteine; Peptide Fragments; Peptides; Phenylalanine; Proline; Tyrosine; Vasopressins | 1976 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
[The pattern of distribution of free amino acids in human amniotic fluid related to the duration of pregnancy. Part I: Changes in concentration in normal pregnancy (author's transl)].
Topics: Alanine; Amino Acids; Amniotic Fluid; Chromatography, Gas; Cysteine; Female; Gestational Age; Glycine; Humans; Hydroxyproline; Methionine; Ornithine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Nerve growth factor mediates signal transduction through trk homodimer receptors.
Topics: 3T3 Cells; Animals; Cell Line; Cysteine; Humans; Kinetics; Macromolecular Substances; Methionine; Mice; Nerve Growth Factors; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Proteins; Signal Transduction; Transfection; Tyrosine; Vanadates | 1992 |
Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cysteine; DNA; Drug Resistance; Kinetics; Molecular Sequence Data; Mutation; Ouabain; Phenylalanine; Polymerase Chain Reaction; Sequence Alignment; Sodium-Potassium-Exchanging ATPase; Tyrosine; Xenopus laevis | 1992 |
Direct identification of residues of the epidermal growth factor receptor in close proximity to the amino terminus of bound epidermal growth factor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chromatography, Affinity; Cross-Linking Reagents; Cysteine; Epidermal Growth Factor; ErbB Receptors; Humans; Iodine Radioisotopes; Mice; Molecular Sequence Data; Phosphotyrosine; Protein Conformation; Tyrosine | 1992 |
Identification of reactive tyrosine residues in cysteine-reactive dehydrogenases. Differences between liver sorbitol, liver alcohol and Drosophila alcohol dehydrogenases.
Topics: Alcohol Dehydrogenase; Animals; Chromatography, High Pressure Liquid; Cysteine; Drosophila; Horses; Kinetics; L-Iditol 2-Dehydrogenase; Liver; Sheep; Tetranitromethane; Tyrosine | 1992 |
Raman spectroscopic study on the structure of ribonuclease F1 and the binding mode of inhibitor.
Topics: Amino Acid Sequence; Binding, Competitive; Cations; Cysteine; Disulfides; Fusarium; Guanosine Monophosphate; Histidine; Hydrogen Bonding; Protein Conformation; Ribonuclease T1; Spectrum Analysis, Raman; Stereoisomerism; Tyrosine | 1991 |
Sequential resonance assignments of oxidized high-potential iron-sulfur protein from Chromatium vinosum.
Topics: Amino Acid Sequence; Bacterial Proteins; Chromatium; Cysteine; Iron-Sulfur Proteins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oxidation-Reduction; Peptides; Protein Conformation; Tryptophan; Tyrosine | 1992 |
Tyrosine transport in a human melanoma cell line as a basis for selective transport of cytotoxic analogues.
Topics: Amino Acids; Amino Acids, Cyclic; Biological Transport, Active; Cysteine; Drug Delivery Systems; Evaluation Studies as Topic; Humans; Kinetics; Melanoma; Sodium; Tumor Cells, Cultured; Tyrosine | 1991 |
On kynureninase activity.
Topics: Animals; Apoenzymes; Benzothiazoles; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrolases; Kynurenine; Liver; Magnesium; Male; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Xanthurenates | 1991 |
Chemical modification of PABA synthase.
Topics: Arginine; Cysteine; Diethyl Pyrocarbonate; Escherichia coli; Folic Acid; Histidine; Iodoacetamide; Phenylglyoxal; Sulfhydryl Reagents; Tetranitromethane; Transaminases; Tyrosine | 1991 |
[Anticancer therapy with amino acid imbalance].
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine | 1991 |
Amino acid analysis of metallothionein.
Topics: Amino Acids; Animals; Autoanalysis; Cysteine; Hydrolysis; Indicators and Reagents; Mammals; Metallothionein; Neurospora crassa; Oxidation-Reduction; Tyrosine | 1991 |
Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine.
Topics: Amines; Amino Acids; Animals; Carbon Isotopes; Carbon-Sulfur Lyases; Cysteine; Cytosol; Fluorine; Histidine; Hydrocarbons, Fluorinated; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Lyases; Lysine; Magnetic Resonance Spectroscopy; Male; Phenols; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1991 |
Interaction of glutathione transferase from horse erythrocytes with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Dithiothreitol; Erythrocytes; Glutathione; Glutathione Transferase; Horses; Hydrogen-Ion Concentration; Lysine; Oxidation-Reduction; Spectrometry, Fluorescence; Spectrum Analysis; Sulfhydryl Reagents; Tetranitromethane; Tyrosine | 1991 |
The neuromelanin of the human substantia nigra.
Topics: Chromatography, High Pressure Liquid; Cysteine; Dopamine; Glutathione; Humans; Melanins; Pyrroles; Substantia Nigra; Tyramine; Tyrosine | 1991 |
Alteration of human myoglobin proximal histidine to cysteine or tyrosine by site-directed mutagenesis: characterization and their catalytic activities.
Topics: Bacteriophages; Cysteine; Genetic Vectors; Histidine; Humans; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Myoglobin; Oxidation-Reduction; Spectrophotometry; Styrene; Styrenes; Tyrosine | 1991 |
Detection of conformational changes in actin by fluorescence resonance energy transfer between tyrosine-69 and cysteine-374.
Topics: Actins; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Cysteine; Dansyl Compounds; Edetic Acid; Energy Transfer; Fluorescent Dyes; Models, Molecular; Muscles; p-Dimethylaminoazobenzene; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Thermodynamics; Tyrosine | 1991 |
Some molecular properties of human seminal transferrin (HSmT) in comparison with human serum transferrin (HSrT).
Topics: Amino Acid Sequence; Cysteine; Fucose; Humans; Male; Molecular Sequence Data; N-Acetylneuraminic Acid; Semen; Sialic Acids; Sulfhydryl Compounds; Transferrin; Tryptophan; Tyrosine | 1991 |
A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor.
Topics: Alanine; Amino Acid Sequence; Antibodies, Monoclonal; Binding Sites; Circular Dichroism; Cysteine; Fluorescence; Genetic Variation; Growth Hormone; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Somatotropin; Tryptophan; Tyrosine | 1991 |
The use of tryptophan mutants in identifying the 296 nm transient absorbing species during the photocycle of bacteriorhodopsin.
Topics: Bacteriorhodopsins; Cysteine; Kinetics; Phenylalanine; Spectrum Analysis; Tryptophan; Tyrosine | 1991 |
Structural studies of the contractile tail sheath protein of bacteriophage T4. 1. Conformational change of the tail sheath upon contraction as probed by differential chemical modification.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Contractile Proteins; Cysteine; Glycoproteins; Magnetic Resonance Spectroscopy; Oxadiazoles; Protein Conformation; T-Phages; Tetranitromethane; Tyrosine; Viral Proteins; Viral Tail Proteins | 1990 |
A novel variant of transthyretin (Tyr114 to Cys) deduced from the nucleotide sequences of gene fragments from familial amyloidotic polyneuropathy in Japanese sibling cases.
Topics: Adult; Amyloidosis; Base Sequence; Cysteine; DNA; Exons; Humans; Male; Molecular Sequence Data; Mutation; Peripheral Nervous System Diseases; Polymerase Chain Reaction; Prealbumin; Tyrosine | 1990 |
Coupled responses of the regions near cysteine-190 and the carboxy terminus of rabbit cardiac tropomyosin: fluorescence and circular dichroism studies.
Topics: Animals; Carboxypeptidases; Carboxypeptidases A; Circular Dichroism; Cysteine; Fluorescence Polarization; Myocardium; Osmolar Concentration; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Tropomyosin; Tyrosine | 1990 |
A point mutation in the cytoplasmic domain of the transferrin receptor inhibits endocytosis.
Topics: Amino Acid Sequence; Animals; Cell Line; Cricetinae; Cysteine; Cytoplasm; DNA; Endocytosis; Gene Expression; Humans; Molecular Sequence Data; Mutation; Receptors, Transferrin; Sequence Homology, Nucleic Acid; Structure-Activity Relationship; Tyrosine | 1990 |
Essential carboxy groups in xylanase A.
Topics: Basidiomycota; Binding Sites; Carbodiimides; Catalysis; Cysteine; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Schizophyllum; Tyrosine; Xylan Endo-1,3-beta-Xylosidase | 1990 |
Metallothionein protein variants generated in rat liver as a result of DNA and RNA ethylations by the carcinogen diethylnitrosamine.
Topics: Alkylation; Animals; Cysteine; Diethylnitrosamine; DNA; Genetic Variation; Liver; Male; Metallothionein; Phenylalanine; Rats; Rats, Inbred Strains; RNA; Tyrosine | 1986 |
Escherichia coli-derived human interferon-gamma with Cys-Tyr-Cys at the N-terminus is partially N alpha-acylated.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Interferon-gamma; Molecular Sequence Data; Molecular Weight; Recombinant Proteins; Tyrosine | 1989 |
N-acetyl-L-tyrosine and N-acetyl-L-cysteine as tyrosine and cysteine precursors during intravenous infusion in humans.
Topics: Acetylcysteine; Adult; Amino Acids, Essential; Biological Availability; Cysteine; Female; Humans; Infusions, Intravenous; Kidney; Male; Parenteral Nutrition, Total; Tyrosine | 1989 |
Some observations on the replacement of the conserved amino acid residues of immunoglobulin domains.
Topics: Alanine; Amino Acids; beta 2-Microglobulin; Computer Graphics; Cysteine; Immunoglobulin Constant Regions; Immunoglobulin Variable Region; Immunoglobulins; Leucine; Serine; Tryptophan; Tyrosine | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Apparent sequence preference in cleavage of linear B-DNA by the Cu(II):thiol system.
Topics: 3-Mercaptopropionic Acid; Cations, Divalent; Copper; Cysteine; Deoxyribonuclease EcoRI; Dithiothreitol; DNA; DNA Damage; DNA, Superhelical; Glutathione; Nucleic Acid Conformation; Plasmids; Solutions; Sulfhydryl Compounds; Tyrosine | 1989 |
A comparison of the antioxidant requirements of proteins with those of synthetic polymers suggests an antioxidant function for clusters of aromatic and bivalent sulphur-containing amino acid residues.
Topics: Antioxidants; Binding Sites; Cysteine; Free Radicals; Ligands; Oxidation-Reduction; Polymers; Sulfhydryl Compounds; Tyrosine | 1989 |
The secondary structure of apolipoproteins in human HDL3 particles after chemical modification of their tyrosine, lysine, cysteine or arginine residues. A Fourier transform infrared spectroscopy study.
Topics: Acylation; Alkylation; Amino Acids; Apolipoproteins E; Arginine; Cyclohexanones; Cysteine; Fourier Analysis; Humans; Lipoproteins, HDL; Low Density Lipoprotein Receptor-Related Protein-1; Lysine; Oxidation-Reduction; Protein Conformation; Receptors, Cell Surface; Spectrophotometry, Infrared; Tetranitromethane; Tyrosine | 1988 |
Effect of chemical modifications on the K99 and K88ab fibrillar adhesins of Escherichia coli.
Topics: Adhesins, Escherichia coli; Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Fimbriae, Bacterial; Lysine; Tyrosine | 1985 |
Inactivation of muscle adenylate kinase by site-specific destruction of tyrosine 95 using potassium ferrate.
Topics: Adenylate Kinase; Amino Acids; Animals; Chromatography, High Pressure Liquid; Cysteine; Iron; Iron Compounds; Kinetics; Muscles; Phosphotransferases; Potassium; Potassium Compounds; Structure-Activity Relationship; Swine; Tyrosine | 1985 |
Chemical modification of alpha 2-adrenoceptors. Possible role for tyrosine in the ligand binding site.
Topics: Binding Sites; Cysteine; Dithiothreitol; Humans; Ligands; Receptors, Adrenergic, alpha; Tetranitromethane; Tyrosine | 1986 |
Evidence for deficiencies of conditionally essential nutrients during total parenteral nutrition.
Topics: Carnitine; Choline Deficiency; Cysteine; Deficiency Diseases; Humans; Parenteral Nutrition, Total; Taurine; Tyrosine | 1986 |
Functional antibody lacking a variable-region disulfide bridge.
Topics: Antibodies; Cysteine; Disulfides; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Protein Conformation; Tyrosine | 1986 |
Amino acid requirements of Eikenella corrodens.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Cysteine; Eikenella corrodens; Histidine; Humans; Lysine; Proline; Tyrosine | 1986 |
Amino acid mixture designed to maintain normal plasma amino acid patterns in infants and children requiring parenteral nutrition.
Topics: Amino Acids; Bilirubin; Body Weight; Child; Child, Preschool; Cholestasis; Cysteine; Electrolytes; Energy Intake; Female; Glucose; Humans; Infant; Male; Parenteral Nutrition; Parenteral Nutrition Solutions; Solutions; Taurine; Tyrosine | 1987 |
Pediatric parenteral amino acid mixture in low birth weight infants.
Topics: Amino Acids; Blood Proteins; Body Weight; Cysteine; Electrolytes; Energy Intake; Female; Glucose; Humans; Infant Food; Infant, Low Birth Weight; Infant, Newborn; Male; Nitrogen; Parenteral Nutrition; Parenteral Nutrition Solutions; Solutions; Tyrosine | 1988 |
Nitrogen balance in adult hospitalized patients with the use of a pediatric amino acid model.
Topics: Adult; Aged; Amino Acids; Cysteine; Electrolytes; Energy Intake; Female; Food, Formulated; Glucose; Hospitalization; Humans; Male; Middle Aged; Nitrogen; Nutritional Physiological Phenomena; Parenteral Nutrition; Parenteral Nutrition Solutions; Solutions; Tyrosine | 1988 |
Structure and stability of gamma-crystallins: tryptophan, tyrosine, and cysteine accessibility.
Topics: Animals; Cattle; Crystallins; Cysteine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1988 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
Properties of a defined mutant of Escherichia coli thymidylate synthase.
Topics: Amino Acids; Cysteine; Escherichia coli; Fluorodeoxyuridylate; Folic Acid; Mutation; Peptide Mapping; Quinazolines; Structure-Activity Relationship; Tetrahydrofolates; Thymidylate Synthase; Tyrosine | 1988 |
Substitution of tyrosine for either cysteine in beta-lactamase prevents release from the membrane during secretion.
Topics: beta-Lactamases; Cysteine; DNA Mutational Analysis; Protein Conformation; Salmonella Phages; Salmonella typhimurium; Structure-Activity Relationship; Tyrosine | 1987 |
Chemical modification of histidine, tyrosine, tryptophan and cysteine residues in carp (Cyprinus carpio) muscle enolase.
Topics: Amino Acids; Animals; Bromosuccinimide; Carps; Cyprinidae; Cysteine; Diethyl Pyrocarbonate; Histidine; Muscles; Nitrogen; Phosphopyruvate Hydratase; Tetranitromethane; Tryptophan; Tyrosine | 1987 |
Unpaired electron migration between aromatic and sulfur peptide units.
Topics: Cysteine; Free Radicals; Oligopeptides; Oxidation-Reduction; Tryptophan; Tyrosine; Water | 1986 |
Amino acid sulfur as a source of sulfate for sulfated proteoglycans produced by Swiss mouse 3T3 cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amino Acids, Sulfur; Animals; Cell Line; Cysteine; Glycosaminoglycans; Methionine; Mice; Proteoglycans; Sulfates; Tyrosine | 1987 |
Fluorescence resonance energy transfer between sites in G-actin. The spatial relationship between Cys-10, Tyr-69, Cys-374, the high-affinity metal and the nucleotide.
Topics: Actins; Affinity Labels; Binding Sites; Cysteine; Energy Transfer; Mathematics; Metals; Nucleotides; Spectrometry, Fluorescence; Structure-Activity Relationship; Tyrosine | 1987 |
Increased yield of the phenylthiocarbamyl-amino acids tyrosine, cysteine and phenylalanine using diethylether-based liquid-liquid extraction.
Topics: Cysteine; Hydrolysis; Indicators and Reagents; Isothiocyanates; Phenylalanine; Protein Hydrolysates; Thiocyanates; Tyrosine | 1987 |
The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Cell Compartmentation; Cloning, Molecular; Cysteine; Endocytosis; Humans; Hyperlipoproteinemia Type II; Mutation; Receptors, LDL; Structure-Activity Relationship; Transfection; Tyrosine | 1986 |
Fluorometry of a DOPA peptide and its thioether.
Topics: Carbon Isotopes; Catechol Oxidase; Catechols; Chromatography, Paper; Cysteine; Dihydroxyphenylalanine; Dipeptides; Ethers; Fluorescence; Fluorometry; Melanoma; Peptides; Phenylalanine; Pigments, Biological; Spectrophotometry; Sulfhydryl Reagents; Sulfur; Tyrosine | 1971 |
Fluorometry of catechol thioethers.
Topics: Catechol Oxidase; Catecholamines; Chromatography, Paper; Cysteine; Fluorometry; Glutathione; Glycine; Indicators and Reagents; Oxidation-Reduction; Tyramine; Tyrosine | 1972 |
Histochemical studies on calcified tissues. I. Amino acid histochemistry of foetal calf and human enamel matrix.
Topics: Amino Acids; Animals; Arginine; Carboxylic Acids; Cattle; Collagen; Cysteine; Dental Enamel; Histidine; Histocytochemistry; Humans; Keratins; Lysine; Microscopy, Phase-Contrast; Odontogenesis; Staining and Labeling; Tooth Germ; Tryptophan; Tyrosine | 1974 |
Histochemical studies on calcified tissues. II. Amino acid histochemistry of developing dentine and bone.
Topics: Amino Acids; Animals; Arginine; Bone Matrix; Calcification, Physiologic; Cattle; Cysteine; Dentin; Dentinogenesis; Histidine; Histocytochemistry; Incisor; Lysine; Odontogenesis; Osteogenesis; Staining and Labeling; Sulfhydryl Compounds; Tooth Germ; Tryptophan; Tyrosine | 1974 |
A glutamyl residue in the active site of triphosphopyridine nucleotide-dependent isocitrate dehydrogenase of pig heart.
Topics: Amides; Animals; Aspartic Acid; Binding Sites; Carbodiimides; Carbon Radioisotopes; Carboxy-Lyases; Catalysis; Cysteine; Drug Synergism; Glutamates; Glycine; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Manganese; Morpholines; Myocardium; NADP; Swine; Temperature; Tyrosine | 1973 |
Irreversible inactivation of rat liver tyrosine aminotransferase.
Topics: Animals; Apoproteins; Binding Sites; Centrifugation, Density Gradient; Cross Reactions; Cysteine; Dihydroxyphenylalanine; Drug Stability; Electrophoresis, Disc; Half-Life; Hot Temperature; Hydroxylamines; Ketoglutaric Acids; Kinetics; Liver; Protein Binding; Pyridoxal Phosphate; Rats; Semicarbazides; Structure-Activity Relationship; Time Factors; Tyrosine; Tyrosine Transaminase; Ultrafiltration | 1974 |
Ferredoxin from a blue-green alga, Aphanothece sacrum (Suringar) Okada.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Cyanobacteria; Cysteine; Ferredoxins; Iron; Leucine; NADH, NADPH Oxidoreductases; Plants; Sulfur; Tyrosine | 1974 |
Evolution of immunoglobulin polypeptide chains: carboxy-terminal of an IgM heavy chain.
Topics: Amino Acid Sequence; Carbon Isotopes; Cysteine; gamma-Globulins; Humans; Tyrosine | 1966 |
Reaction of proteins with glutaraldehyde.
Topics: Aldehydes; Animals; Antibodies; Cattle; Chromatography; Cysteine; gamma-Globulins; Histidine; Imidazoles; Immunodiffusion; Immunoelectrophoresis; Ovalbumin; Phenols; Precipitin Tests; Proteins; Serum Albumin; Spectrophotometry; Tyrosine; Ultracentrifugation | 1968 |
The chemical composition of wool. 7. Separation and analysis of orthocortex and paracortex.
Topics: Amino Acids; Animals; Cell Membrane; Centrifugation, Density Gradient; Cysteine; Cystine; Glycine; Gold; Leucine; Methods; Microscopy, Electron; Phenylalanine; Sheep; Staining and Labeling; Tyrosine; Ultrasonics; Wool | 1968 |
The interaction of gamma-globulin with lipids.
Topics: Animals; Arginine; Bence Jones Protein; Benzoates; Cattle; Chickens; Cholesterol; Cysteine; gamma-Globulins; Histidine; Horses; Humans; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Mercury; Methionine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Rabbits; Sodium Chloride; Sphingomyelins; Swine; Time Factors; Tyrosine | 1968 |
Alkaline phosphatase of Drosophila melanogaster. I. Partial purification and characterization.
Topics: Alkaline Phosphatase; Alleles; Ammonium Sulfate; Animals; Butanols; Cations, Divalent; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyanides; Cysteine; Drosophila melanogaster; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Larva; Organophosphorus Compounds; Phosphates; Structure-Activity Relationship; Tyrosine; Zinc | 1972 |
Alkaline phosphatase of Drosophila melanogaster. II. Biochemical comparison among four allelic forms.
Topics: Alkaline Phosphatase; Alleles; Animals; Chromatography, DEAE-Cellulose; Cyanides; Cysteine; Drosophila melanogaster; Drug Stability; Electrophoresis, Starch Gel; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Larva; Molecular Biology; Organophosphorus Compounds; Phosphates; Structure-Activity Relationship; Tyrosine | 1973 |
The designation of the major guinea-pig neural lobe protein as a neurophysin.
Topics: Animals; Antigens; Biological Assay; Cross Reactions; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycine; Guinea Pigs; Histidine; Immunodiffusion; Isoleucine; Lysine; Male; Methionine; Molecular Weight; Neurophysins; Pituitary Gland, Posterior; Sulfur Radioisotopes; Tyrosine | 1973 |
Potent in vitro inhibitors of tyrosinase: metal-binding fractions of tobacco smoke condensate.
Topics: Basidiomycota; Catechol Oxidase; Copper; Cyanides; Cysteine; Dihydroxyphenylalanine; Kinetics; Metals; Nicotiana; Phenanthrolines; Plants, Toxic; Quinolines; Salicylates; Smoke; Thiocarbamates; Tyrosine | 1974 |
[Cytochemical studies on cells of extramedullary plasmacytoma of the stomach].
Topics: Amino Acids; Cysteine; Cystine; Glycogen; Glycols; Glycosaminoglycans; Histocytochemistry; Humans; Male; Middle Aged; Plasmacytoma; Stomach Neoplasms; Tyrosine | 1967 |
In vivo studies on the mechanism of the antifibrinolytic action of E-aminocaproic acid (EACA).
Topics: Aminocaproates; Animals; Antifibrinolytic Agents; Caseins; Cattle; Cysteine; Factor XIII; Fibrinolysin; Fibrinolysis; Fibrinolytic Agents; Humans; Plasminogen; Streptokinase; Trichloroacetic Acid; Tyrosine | 1968 |
Studies on the properties of chemically modified actin. 3. Carbethoxylation.
Topics: Adenosine Triphosphatases; Alkylation; Carbonates; Chemical Phenomena; Chemistry; Cysteine; Histidine; Muscle Proteins; Nucleotides; Optical Rotatory Dispersion; Tyrosine; Viscosity | 1969 |
On the active site of myosin A-adenosine triphosphatase. IX. Chemical modification of the enzyme by monoiodoacetamide.
Topics: Adenosine Triphosphatases; Amides; Animals; Binding Sites; Chloromercuribenzoates; Chromatography; Cysteine; Dextrans; Edetic Acid; Enzyme Activation; Ethylmaleimide; Histidine; Iodoacetates; Lysine; Muscle Proteins; Nitrobenzenes; Rabbits; Sulfonamides; Sulfonic Acids; Toluene; Tyrosine | 1970 |
[Histochemical studies of the anal glands in rabbits].
Topics: Animals; Carbohydrates; Cysteine; Female; Glycogen; Glycosaminoglycans; Histidine; Histocytochemistry; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Lipids; Male; Nucleoproteins; Perianal Glands; Rabbits; Succinate Dehydrogenase; Tryptophan; Tyrosine | 1970 |
Acute papulopustular acne associated with prolonged intravenous hyperalimentation.
Topics: Acne Vulgaris; Adult; Crohn Disease; Cysteine; Diet; Enteral Nutrition; Female; Glutamates; Humans; Intestinal Fistula; Male; Parenteral Nutrition; Tyrosine; Vena Cava, Superior | 1972 |
Thiolysis of dinitrophenylated myosin with restoration of adenosine triphosphatase activity.
Topics: Adenosine Triphosphatases; Alkylation; Amino Acids; Animals; Calcium; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Cystine; Disulfides; Fluorine; Mercaptoethanol; Myosins; Nitrobenzenes; Pepsin A; Peptides; Potassium; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds; Tritium; Trypsin; Tyrosine | 1972 |
Relationship of cysteine and tyrosine residues to adenosine triphosphate hydrolysis by mitochondrial adenine triphosphatase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Buffers; Cattle; Chemical Phenomena; Chemistry; Cysteine; Disulfides; Drug Stability; Hydrolysis; Iodoacetates; Methane; Mitochondria, Muscle; Myocardium; Nitro Compounds; Sodium; Sulfhydryl Compounds; Sulfhydryl Reagents; Tyrosine | 1973 |
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine; Magnesium; Methionine; Niacinamide; Obstetric Labor Complications; Phenylalanine; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Rheumatic Heart Disease; Sodium; Tryptophan; Tyrosine; Valine; Vitamin E | 1974 |
Cystathioninuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carcinoma, Hepatocellular; Child, Preschool; Cysteine; Diet Therapy; Female; Galactosemias; Glycogen; Humans; Infant; Intellectual Disability; Liver Neoplasms; Male; Maple Syrup Urine Disease; Methionine; Middle Aged; Neuroblastoma; Phenylketonurias; Portal Vein; Pyridoxine; Serine; Sulfisoxazole; Tyrosine | 1967 |
The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Glutamates; Glycine; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lysine; Methionine; Periodic Acid; Phenylalanine; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan; Tyrosine | 1968 |
Reaction of myosin with 1-fluoro-2, 4-dinitrobenzene at low ionic strength.
Topics: Adenosine Triphosphate; Calcium Chloride; Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gel; Cysteine; Dinitrophenols; Diphosphates; Edetic Acid; Fluorine; Hydrogen-Ion Concentration; Magnesium; Muscle Proteins; Nitrobenzenes; Nucleotides; Potassium Chloride; Solutions; Tritium; Tyrosine | 1969 |
EPR study of Cu(II) complexes of tridentate amino acids.
Topics: Amino Acids; Aminobutyrates; Arginine; Chelating Agents; Chemical Phenomena; Chemistry; Chlorides; Copper; Cysteine; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Methionine; Ornithine; Polyamines; Propionates; Sodium Hydroxide; Time Factors; Tryptophan; Tyrosine | 1971 |
Role of tyrosine in the substrate binding site of mitochondrial L-malate dehydrogenase from bovine heart muscle.
Topics: Acetates; Acylation; Animals; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxylic Acids; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chlorides; Cysteine; Dicarboxylic Acids; Enzyme Activation; Fumarates; Glutamates; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Kinetics; Malate Dehydrogenase; Malates; Mercuribenzoates; Methane; Mitochondria, Muscle; Myocardium; NAD; Spectrophotometry; Sulfates; Sulfonic Acids; Tyrosine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
ESR studies of the low temperature irradiation of keratin and its component amino acids.
Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Indoles; Keratins; Muramidase; Phenylalanine; Radiation Effects; Tryptophan; Tyrosine; Tyrothricin; Ultraviolet Rays; Wool | 1972 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase.
Topics: Amino Acids; Animals; Antibodies; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Crystallization; Cysteine; Cytoplasm; Diffusion; Dihydroxyphenylalanine; Fenclonine; Glutamates; Isoelectric Focusing; Isoenzymes; Ketoglutaric Acids; Male; Methionine; Mitochondria, Liver; Molecular Weight; Monoiodotyrosine; Oxaloacetates; Phenylpyruvic Acids; Rats; Stereoisomerism; Tryptophan; Tyrosine; Tyrosine Transaminase; Ultracentrifugation; Vibration | 1971 |
Quaternary-structure-dependent proton dissociation of tyrosines, lysines and cysteines in human hemoglobin.
Topics: Binding Sites; Carboxyhemoglobin; Chloromercuribenzoates; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Hemoglobins; Humans; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Lysine; Mathematics; Protein Binding; Protein Conformation; Spectrophotometry; Tyrosine; Ultracentrifugation | 1974 |
Alpha-aminocyclic and bicyclic alkane carboxylic acids: differential effects on selected amino acids of rat brain cortex.
Topics: Amines; Amino Acids; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carboxylic Acids; Cerebral Cortex; Cyclohexanecarboxylic Acids; Cycloparaffins; Cysteine; Isoleucine; Male; Methionine; Phenylalanine; Rats; Structure-Activity Relationship; Time Factors; Tyrosine; Valine | 1974 |
Molecular conformation and cooperativity in hemoglobin.
Topics: Binding Sites; Carbon Monoxide; Cyanides; Cysteine; Diphosphoglyceric Acids; Fluoroacetates; Fourier Analysis; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Iron Isotopes; Ligands; Magnetic Resonance Spectroscopy; Models, Structural; Oxygen; Oxyhemoglobins; Phosphorus Isotopes; Protein Binding; Protein Conformation; Spectrophotometry; Tyrosine | 1973 |
50-S ribosomal proteins. Purification and partial characterization of two acidic proteins, A 1 and A 2, isolated from 50-S ribosomes of Escherichia coli.
Topics: Alanine; Amino Acids; Autoanalysis; Bacterial Proteins; Chromatography, DEAE-Cellulose; Cysteine; Electrophoresis; Escherichia coli; Histidine; Isoelectric Focusing; Molecular Weight; Ribosomes; Sodium Dodecyl Sulfate; Tryptophan; Tyrosine; Ultracentrifugation | 1972 |
Histochemical studies on calcified tissues. 3. Amino acid histochemistry of carious dentine and dentinal reactions to caries.
Topics: Amino Acids; Arginine; Cysteine; Decalcification Technique; Dental Caries; Dentin; Histidine; Histocytochemistry; Humans; Lysine; Tryptophan; Tyrosine | 1974 |
Modification of transfer ribonucleic acid by an alkylating fragment from S-(1,2-dichlorovinyl)-L-cysteine.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Cysteine; Escherichia coli; Histidine; Liver; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Species Specificity; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Transfer RNA Aminoacylation; Tyrosine; Vinyl Compounds | 1974 |
Chemical modifications of Escherichia coli ribosomal proteins S4, S7, and S8 in regard to their capacity for binding 16 S RNA.
Topics: Amino Acids; Bacterial Proteins; Benzoates; Binding Sites; Chromatography, Ion Exchange; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Lysine; Macromolecular Substances; Molecular Weight; Nitro Compounds; Protein Binding; Ribosomes; RNA, Bacterial; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Tyrosine | 1974 |
Effect of thiol compounds on melanin formation by tyrosinase.
Topics: Ascorbic Acid; Basidiomycota; Catalysis; Catechol Oxidase; Catechols; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Crystallization; Cysteine; Dihydroxyphenylalanine; Glutathione; Infrared Rays; Kinetics; Magnetic Resonance Spectroscopy; Melanins; Oxidation-Reduction; Quinones; Spectrophotometry; Sulfhydryl Compounds; Tritium; Tyrosine; Ultraviolet Rays | 1972 |
Assay, properties and tissue distribution of p-hydroxyphenylpyruvate hydroxylase.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Animals, Newborn; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteine; Enzyme Activation; Female; Fetus; Haplorhini; Humans; Hydrogen-Ion Concentration; Kidney; Liver; Mixed Function Oxygenases; Opossums; Organ Specificity; Oxygen; Phenols; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Rats; Salmon; Species Specificity; Spectrophotometry, Ultraviolet; Tyrosine | 1972 |
Chromogenesis mirabilis in Streptomyces griseus.
Topics: Agar; Amino Acids; Catechol Oxidase; Cell-Free System; Culture Media; Cysteine; Dihydroxyphenylalanine; Melanins; Oxidoreductases; Peptones; Species Specificity; Spectrophotometry; Stereoisomerism; Streptomyces; Streptomyces griseus; Tritium; Tyrosine | 1972 |
Human carbonic anhydrases. X. Preparation of large peptide fragments of carbonic anhydrase B used for sequence studies.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Carbonic Anhydrases; Chromatography, Gel; Cyanogen Bromide; Cysteine; Erythrocytes; Freeze Drying; Guanidines; Humans; Hydrogen-Ion Concentration; Lysine; Methionine; Peptides; Phenylalanine; Solubility; Spectrophotometry, Ultraviolet; Trypsin; Tryptophan; Tyrosine | 1973 |
Plasma amino acid abnormalities in chronic renal failure.
Topics: Adult; Amino Acids; Cysteine; Cystine; Disulfides; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine | 1972 |
Selective chemical cleavage of tryptophanyl peptide bonds in peptides and proteins.
Topics: Bromine; Chemical Phenomena; Chemistry; Cyclohexanes; Cysteine; Glucagon; Hydrogen-Ion Concentration; Ketones; Kinetics; Magnetic Resonance Spectroscopy; Methionine; Muramidase; Oxidation-Reduction; Peptides; Potentiometry; Ribonucleases; Spectrophotometry, Ultraviolet; Sulfonic Acids; Sulfoxides; Tryptophan; Tyrosine | 1972 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
Selective modification of tyrosine and cysteine residues in aspartate aminotransferase from pig heart cytosol.
Topics: Alkylation; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Cysteine; Cytosol; In Vitro Techniques; Maleimides; Myocardium; Nitro Compounds; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Swine; Trypsin; Tyrosine | 1973 |
Peroxidase mediated oxidation of tyrosine: tyrosine hydroxylation in tea leaves.
Topics: Ascorbic Acid; Buffers; Cysteine; Dihydroxyphenylalanine; Glutathione; Hydrogen-Ion Concentration; Hydroxylation; Melanins; Mercaptoethanol; Oxidation-Reduction; Peroxidases; Sulfites; Tea; Tyrosine | 1973 |
Relative reactivities of nucleophilic centers in some monopeptides.
Topics: Acetamides; Alkylation; Amides; Azirines; Chemical Phenomena; Chemistry; Cysteine; Histidine; Iodoacetates; Methionine; Peptides; Protein Conformation; Structure-Activity Relationship; Tyrosine | 1973 |
Nutrient media for plant parasitic nematodes. V. Amino acid nutrition of Aphelenchoides rutgersi.
Topics: Alanine; Amino Acids; Aminobutyrates; Culture Media; Cysteine; Cystine; Glutamine; Histidine; Isoleucine; Leucine; Methionine; Mitosporic Fungi; Nematoda; Phenylalanine; Reproduction; Tyrosine | 1973 |
Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.
Topics: Alkylation; Amino Acids; Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Deoxyribonucleases; Disulfides; Histidine; Methane; Nitro Compounds; Pancreas; Peptides; Tyrosine | 1973 |
Reaction of cytoplasmic aspartate aminotransferase with tetranitromethane.
Topics: Animals; Aspartate Aminotransferases; Binding Sites; Carbon Isotopes; Chromatography, Gel; Cyanides; Cysteine; Cytosol; Ethylmaleimide; Methane; Myocardium; Nitro Compounds; Protein Binding; Protein Denaturation; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Swine; Time Factors; Tyrosine | 1973 |
Chlorination studies. II. The reaction of aqueous hypochlorous acid with alpha-amino acids and dipeptides.
Topics: Aldehydes; Amino Acids; Chlorine; Chromatography, Gas; Cysteine; Cystine; Dipeptides; Glutamates; Mass Spectrometry; Nitriles; Structure-Activity Relationship; Tyrosine | 1973 |
Photo-oxidation of lens proteins by sunlight in the presence of fluorescent derivatives of kynurenine, isolated from the human lens.
Topics: Amino Acids; Chromatography, Gel; Color; Crystallins; Cysteine; Fluorescence; Histidine; Humans; Kynurenine; Methionine; Oxidation-Reduction; Peptide Hydrolases; Photochemistry; Spectrum Analysis; Sunlight; Tryptophan; Tyrosine | 1973 |
On the mechanism of formation of a partially active aldolase by tryptic digestion.
Topics: Acetates; Amino Acid Sequence; Amino Acids; Animals; Bromine; Chloromercuribenzoates; Cysteine; Electrophoresis, Polyacrylamide Gel; Fructose-Bisphosphate Aldolase; Fructosephosphates; Kinetics; Molecular Weight; Muscle Proteins; Muscles; Peptide Chain Termination, Translational; Peptides; Rabbits; Trypsin; Tryptophan; Tyrosine | 1973 |
Identification of melanoma cells by formaldehyde-induced fluorescence.
Topics: Adenocarcinoma; Cell Line; Culture Techniques; Cysteine; Dopamine; Fluorescence; Formaldehyde; HeLa Cells; Humans; Melanoma; Tyrosine; Ultraviolet Rays | 1974 |
Synthesis and catalytic properties of the heptapeptide L-seryl-L-prolyl-L-cysteinyl-L-steryl-alpha-L-glutamyl-L-threonyl-L-tyrosine.
Topics: Acetates; Carboxypeptidases; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dicyclohexylcarbodiimide; Esters; Glutamates; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrophenols; Oligopeptides; Optical Rotation; Proline; Serine; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Threonine; Tyrosine | 1974 |
Proteins lacking certain amino acids.
Topics: Arginine; Aspartic Acid; Cysteine; Glutamates; Histidine; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Tryptophan; Tyrosine; Valine | 1974 |
Tyrosyl transfer ribonucleic acid synthetase from Bacillus stearothermophilus. Preparation and properties of the crystallizable enzyme.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Ammonium Sulfate; Bacillus; Carbon Radioisotopes; Cellulose; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Cysteine; Drug Stability; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Macromolecular Substances; Molecular Weight; Peptide Fragments; Phosphorus Radioisotopes; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Sulfhydryl Compounds; Transfer RNA Aminoacylation; Trypsin; Tyrosine | 1974 |
Circular dichroism of squid retinochrome.
Topics: Animals; Circular Dichroism; Cysteine; Decapodiformes; Hydrogen-Ion Concentration; Light; Optical Rotation; Photochemistry; Protein Conformation; Protein Denaturation; Retinal Pigments; Spectrophotometry; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1974 |
Effect of concentrations of ammonium molybdate, diammonium hydrogen phosphate, formaldehyde, and minerals in mixture on the synthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cysteine; Formaldehyde; Glycine; Histidine; Minerals; Molybdenum; Organophosphorus Compounds; Quaternary Ammonium Compounds; Sterilization; Sunlight; Tyrosine | 1974 |
Physicochemical and catalytic properties of aspartate aminotransferase selectively modified at the tyrosine and cysteine residues.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Binding Sites; Carbon Radioisotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Electrophoresis, Paper; Enzyme Activation; Ethylmaleimide; Ketoglutarate Dehydrogenase Complex; Methane; Myocardium; Nitro Compounds; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tyrosine | 1974 |
Tyrosine phenol lyase. I. Purification, crystallization, and properties.
Topics: Alanine; Amino Acids; Ammonia; Catechols; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Culture Media; Cysteine; Electrophoresis; Escherichia coli; Feedback; Kinetics; Lyases; Methods; Molecular Weight; Phenols; Protamines; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Tyrosine; Ultracentrifugation | 1970 |
Horse liver alcohol dehydrogenase. The primary structure of an N-terminal part of the protein chain of the ethanol-active isoenzyme.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Binding Sites; Carbon Isotopes; Chromatography, Gel; Chymotrypsin; Crustacea; Cyanides; Cysteine; Ethanol; Glyceraldehyde-3-Phosphate Dehydrogenases; Horses; Iodoacetates; Isoenzymes; Liver; Maleates; Pepsin A; Serine; Species Specificity; Swine; Trypsin; Tryptophan; Tyrosine | 1970 |
[Resynthesis of insulin in the liver of intact and adrenalectomized animals and animals with resected pancreas].
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Cysteine; Glycine; Guinea Pigs; Immune Sera; Insulin; Islets of Langerhans; Liver; Pancreas; Pancreatectomy; Rats; Sulfur Isotopes; Tyrosine | 1970 |
Composition and subunit structure of glycerol kinase from Escherichia coli.
Topics: Acridines; Adenosine Triphosphate; Amino Acids; Chemical Phenomena; Chemical Precipitation; Chemistry, Physical; Chromatography, DEAE-Cellulose; Chromatography, Gel; Colorimetry; Crystallization; Cysteine; Electrophoresis; Escherichia coli; Glycerol; Hydrazines; Iodoacetates; Macromolecular Substances; Methods; Molecular Weight; Peptides; Phosphorus Isotopes; Phosphotransferases; Protein Denaturation; Quaternary Ammonium Compounds; Spectrophotometry; Sulfates; Sulfhydryl Reagents; Tetroses; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 1971 |
Fractionation of the nonpolar transfer ribonucleic acids from rat liver, yeast, and Escherichia coli by partition chromatography.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Chromatography, Gel; Cysteine; Escherichia coli; Genetic Code; Glutamates; Leucine; Liver; Lysine; Methionine; Nucleosides; Phenylalanine; Rats; RNA, Transfer; Saccharomyces; Serine; Species Specificity; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Sugar transport. 3. Purification and properties of a phosphocarrier protein (HPr) of the phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli.
Topics: Amino Acids; Bacterial Proteins; Carbon Isotopes; Carrier Proteins; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Hexosamines; Histidine; Hot Temperature; Hydrolysis; Imidazoles; Molecular Weight; Phosphoenolpyruvate; Phosphoproteins; Phosphorus Isotopes; Phosphotransferases; Protein Binding; Proteins; Spectrophotometry; Time Factors; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 1971 |
Simple and rapid procedure for chromatographic identification of multiple transfer RNA species from Escherichia coli.
Topics: Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Cysteine; Escherichia coli; Ethanol; Isotope Labeling; Methods; Phenylalanine; RNA, Transfer; Sulfur Isotopes; Tryptophan; Tyrosine | 1971 |
A comparative study of proteolytic activities in the venoms of some North American snakes.
Topics: Animals; Chloromercuribenzoates; Cysteine; Edetic Acid; Enzymes; Glutathione; In Vitro Techniques; Lysine; Peptide Hydrolases; Phenanthrolines; Physiology, Comparative; Snakes; Thioglycolates; Tyrosine; Venoms | 1966 |
A histochemical study on the Reichert membrane of the rat's placenta.
Topics: Animals; Arginine; Cysteine; Cystine; Female; Ferricyanides; Histocytochemistry; Indicators and Reagents; Membranes; Neuraminic Acids; Placenta; Polysaccharides; Pregnancy; Rats; Tryptophan; Tyrosine | 1965 |
In vitro growth inhibition of S-91 mouse melanomas by tyrosinase substrate analogs with and without L-cysteine.
Topics: Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Cysteine; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1967 |
Reaction of tyrosine oxidation products with proteins of the lens.
Topics: Animals; Ascorbic Acid; Cataract; Catechol Oxidase; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Crystallins; Cysteine; Dihydroxyphenylalanine; Edetic Acid; Fluorescence; Iron; Naphthoquinones; Oxidation-Reduction; Proteins; Sulfates; Sulfur; Tyrosine | 1968 |
Inhibition of melanin formation by sulfhydryl compounds.
Topics: Animals; Carbon Isotopes; Catechol Oxidase; Chromatophores; Culture Techniques; Cysteine; Dihydroxyphenylalanine; Electrophoresis; Glutathione; Melanins; Mice; Mixed Function Oxygenases; Neoplasms, Experimental; Sulfhydryl Compounds; Sulfur Isotopes; Tritium; Tyrosine | 1969 |
The localization of N6-(delta 2-isopentenyl) adenosine among the acceptor species of transfer ribonucleic acid of Lactobacillu acidophilus.
Topics: Alkenes; Amino Acids; Anhydrides; Carbon Isotopes; Cellulose; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Ion Exchange; Culture Media; Cysteine; Genetic Code; Lactobacillus acidophilus; Leucine; Mevalonic Acid; Nucleosides; RNA, Bacterial; RNA, Transfer; Serine; Tritium; Tryptophan; Tyrosine | 1969 |
Inhibition of S-91 mouse melanoma metastases and growth by D-penicillamine.
Topics: Animals; Catechol Oxidase; Copper; Cysteine; Melanoma; Mice; Neoplasm Metastasis; Penicillamine; Tyrosine | 1969 |
Effect of calcium ion on S-100, a protein of the nervous system.
Topics: Acrylates; Animals; Antigens; Brain Chemistry; Calcium; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Electrophoresis; Fluorometry; Immune Sera; Immunodiffusion; Magnesium; Methods; Nerve Tissue Proteins; Optical Rotatory Dispersion; Phenylalanine; Potassium; Protein Binding; Protein Denaturation; Quaternary Ammonium Compounds; Rabbits; Sodium; Solubility; Spectrophotometry; Strontium; Sulfhydryl Compounds; Time Factors; Tryptophan; Tyrosine; Urea; Viscosity | 1969 |
Chemical composition of exosporium from spores of Bacillus cereus.
Topics: Amino Acids; Bacillus cereus; Calcium; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography; Cysteine; Cystine; Fatty Acids; Histidine; Lipids; Methionine; Phospholipids; Phosphorus; Polysaccharides; Proteins; Spores; Tyrosine | 1970 |
Carboxy-terminal structure of the chain of human IgA myeloma proteins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Antigens; Aspartic Acid; Bence Jones Protein; Blood Protein Electrophoresis; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanides; Cysteine; Glutamates; Glycine; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin A; Immunoglobulin G; Iodine Isotopes; Methods; Models, Structural; Oxidation-Reduction; Peptides; Rabbits; Sulfides; Thiocyanates; Threonine; Tyrosine; Valine | 1971 |
Unusual effects of reducing agents on 0-diphenoloxidase of Mycobacterium leprae.
Topics: Animals; Ascorbic Acid; Azides; Basidiomycota; Catechol Oxidase; Cell-Free System; Cyanides; Cysteine; Cystine; Dihydroxyphenylalanine; Glutathione; Humans; Manometry; Melanins; Melanoma; Mice; Mycobacterium leprae; Oxidation-Reduction; Quinones; Skin; Species Specificity; Spectrophotometry; Spleen; Stereoisomerism; Tissue Extracts; Tyrosine | 1971 |
Oxygen equilibrium and circular dichroism of hemoglobin-Rainer ( 2 2 1 45Tyr leads to Cys).
Topics: Amino Acid Sequence; Amino Acids; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Disulfides; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Oxygen; Peptides; Protein Conformation; Spectrophotometry; Sulfhydryl Compounds; Tyrosine; Ultraviolet Rays | 1972 |
The deoxygenation kinetics of hemoglobin Rainier ( 2 145 tyr change to cys).
Topics: Cysteine; Disulfides; Drug Stability; Glycerophosphates; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kinetics; Oxygen; Peptides; Protein Binding; Protein Conformation; Tyrosine | 1972 |
Chemical modification of the high-affinity bilirubin-binding site of human-serum albumin.
Topics: Acylation; Arginine; Aspirin; Bilirubin; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Electrophoresis; Histidine; Humans; Lysine; Protein Binding; Protein Conformation; Serum Albumin; Tryptophan; Tyrosine | 1972 |
Selective free radical reactions with proteins and enzymes: reactions of inorganic radical anions with amino acids.
Topics: Alanine; Amino Acids; Bromides; Carbonates; Chlorides; Cysteine; Free Radicals; Histidine; Hydrogen-Ion Concentration; Iodides; Kinetics; Methionine; Muramidase; Proteins; Radiation Effects; Radiochemistry; Spectrophotometry; Thiocyanates; Tryptophan; Tyrosine | 1972 |
Band-shape analysis and display of fine structure in protein spectra: a new approach to perturbation spectroscopy.
Topics: Acetates; Animals; Apoproteins; Aspartate Aminotransferases; Cattle; Chymotrypsinogen; Computers; Cysteine; Egg White; Ethanol; Glucagon; Mathematics; Methods; Muramidase; Myocardium; Pancreas; Phenylalanine; Protein Conformation; Protein Denaturation; Ribonucleases; Spectrophotometry; Swine; Tryptophan; Tyrosine; Ultraviolet Rays; Urea | 1972 |
The labelling of proteins by irradiation in tritiated water.
Topics: Alkylation; Amino Acids; Animals; Cetacea; Chromatography, Ion Exchange; Cysteine; Egg White; Endopeptidases; Histidine; Isotope Labeling; Leucyl Aminopeptidase; Muramidase; Myoglobin; Phenylalanine; Photolysis; Pronase; Radiation Effects; Tritium; Tryptophan; Tyrosine; Ultraviolet Rays; Water; Wool | 1972 |
Localization of affinity-labeled residues in the primary structure of anti-dinitrophenyl antibody raised in strain 13 guinea pigs.
Topics: Amino Acid Sequence; Amino Acids; Animals; Antibodies; Binding Sites; Boric Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Cyanogen Bromide; Cysteine; Diazonium Compounds; Disulfides; Fluorine; Guinea Pigs; Haptens; Hemocyanins; Immunoglobulin G; Mollusca; Nitrobenzenes; Peptides; Spectrophotometry; Tyrosine | 1972 |
[Histochemical studies on female genital organs during fetal development. VI. Protein histochemistry of the uterine tubes].
Topics: Arginine; Cysteine; Cystine; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Lysine; Pregnancy; Proteins; Tryptophan; Tyrosine | 1972 |
Ligand exchange amino acid analysis: resolution of some amino sugars and cysteine derivatives.
Topics: Acetates; Amino Acids; Arginine; Autoanalysis; Buffers; Cysteine; Galactose; Glucosamine; Hexosamines; Histidine; Hydrogen-Ion Concentration; Ion Exchange Resins; Mannose; Methods; Ovalbumin; Phenylalanine; Sodium; Tyrosine; Zinc | 1971 |
An immunoglobulin light chain of subgroup III-1 of lambda type with a free sulfhydryl group.
Topics: Amino Acid Sequence; Ammonium Sulfate; Bence Jones Protein; Chemical Precipitation; Chromatography, Gel; Cysteine; Dansyl Compounds; Dithiothreitol; Electrophoresis; Guanidines; Humans; Immunoglobulin G; Immunoglobulins; Iodine Isotopes; Iodoacetates; Methylation; Multiple Myeloma; Myeloma Proteins; Oxidation-Reduction; Peptides; Protein Denaturation; Sulfhydryl Compounds; Tryptophan; Tyrosine; Urea; Valine | 1971 |
Chemical modification of the active site of yeast invertase.
Topics: Acetamides; Alkylation; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Dialysis; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Iodides; Iodine; Iodoacetates; Iodoproteins; Kinetics; Mercaptoethanol; Mercaptoethylamines; Mercury; Methane; Methionine; Models, Chemical; Models, Structural; Nitrates; Nitro Compounds; Organometallic Compounds; Saccharomyces; Spectrophotometry; Sucrase; Tyrosine | 1971 |
[Histochemical studies of female genitalia during fetal development. IV. Protein histochemistry of the uterus].
Topics: Alloxan; Amino Acids; Arginine; Cervix Uteri; Cysteine; Cystine; Cytoplasm; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Imidazoles; Lysine; Nitrobenzenes; Proteins; Schiff Bases; Sulfhydryl Compounds; Tetrazolium Salts; Tryptophan; Tyrosine; Uterus | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Organ-specific inhibition of human alkaline phosphatase isoenzymes of liver, bone, intestine and placenta; L-phenylalanine, L-tryptophan and L homoarginine.
Topics: Alkaline Phosphatase; Amino Acids; Bile Acids and Salts; Bone and Bones; Cysteine; Dihydroxyphenylalanine; Guanidines; Histidine; Humans; Intestines; Isoenzymes; Liver; Organ Specificity; Phenylalanine; Phosphoric Acids; Placenta; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tyrosine | 1971 |
Relative standard deviations in determinations of amino acids.
Topics: Amino Acids; Analysis of Variance; Cysteine; Factor Analysis, Statistical; Methionine; Plant Proteins; Tryptophan; Tyrosine | 1971 |
Sequence and structure of a cysteinyl flavin peptide from monoamine oxidase.
Topics: Amino Acid Sequence; Aminopeptidases; Binding Sites; Chromatography, Paper; Cysteine; Electrophoresis, Paper; Flavin-Adenine Dinucleotide; Fluorometry; Formates; Glycine; Hydrolysis; Indicators and Reagents; Liver; Monoamine Oxidase; Oxidation-Reduction; Peptides; Protein Binding; Serine; Spectrophotometry; Tyrosine | 1971 |
Luminescence of ribonuclease A.
Topics: Alkylation; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Cold Temperature; Cysteine; Cystine; Dipeptides; Disulfides; Fluorometry; Insulin; Iodoacetates; Kinetics; Luminescent Measurements; Lysine; Mathematics; Mercaptoethanol; Oxidation-Reduction; Pancreas; Peptides; Ribonucleases; Temperature; Tyrosine; Urea | 1971 |
Antagonistic activities of derivatives of cystinyl-tyrosyl-tyrosine to actions of oxytocin.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Chickens; Cysteine; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle, Smooth; Oxytocin; Peptide Chain Initiation, Translational; Peptides; Rats; Time Factors; Tyrosine; Uterus | 1971 |
The effect of tetranitromethane on apo-aspartate-aminotransferase from pig heart.
Topics: Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Cysteine; Methane; Myocardium; Nitro Compounds; Swine; Tyrosine | 1971 |
The basic protein responsible for the clotting of guinea pig semen.
Topics: Acrylic Resins; Amino Acids; Animals; Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis; Gels; Guinea Pigs; Male; Molecular Weight; Proline; Prostate; Proteins; Semen; Seminal Vesicles; Tyrosine; Ultracentrifugation; Viscosity | 1967 |
Haemoglobin Rainier: beta-145 (HC2) tyrosine leads to cysteine and haemoglobin Bethesda: beta-145 (HC2) tyrosine leads to histidine.
Topics: Amino Acid Sequence; Blood Protein Electrophoresis; Carboxypeptidases; Chromatography, Paper; Cysteine; Hemoglobins, Abnormal; Histidine; Humans; Peptides; Trypsin; Tyrosine | 1971 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
Chemistry of gonadotrophins in relation to their antigenic properties.
Topics: Amino Acids; Antigens; Chorionic Gonadotropin; Complement Fixation Tests; Cysteine; Follicle Stimulating Hormone; Gonadotropins; Histidine; Humans; Immune Sera; Luteinizing Hormone; Methionine; Neuraminic Acids; Prolactin; Radioimmunoassay; Tryptophan; Tyrosine | 1969 |
[Effect of light and reducing substances on the reaction of tyrosine with 1-nitroso-2-naphthol].
Topics: Catalysis; Chemical Phenomena; Chemistry; Cysteine; Indicators and Reagents; Light; Mercaptoethanol; Naphthalenes; Nitrites; Spectrophotometry; Trichloroacetic Acid; Tyrosine | 1969 |
A cytochemical study of phaeomelanin formation in feather papillae of New Hampshire chick embryos.
Topics: Animals; Autoradiography; Carbon Isotopes; Chick Embryo; Chromatophores; Cysteine; Feathers; Histocytochemistry; Melanins; Melanocytes; Pigments, Biological; Quinones; Thiocarbamates; Tyrosine | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Morphological and histochemical studies on fibrillopathia epitheliocapsularis.
Topics: Aged; Amylases; Arginine; Cataract; Cysteine; Cystine; Endopeptidases; Epithelium; Eye Diseases; Histocytochemistry; Humans; Hyaluronoglucosaminidase; In Vitro Techniques; Lens, Crystalline; Microscopy, Electron; Middle Aged; Ribonucleases; Time Factors; Tryptophan; Tyrosine | 1969 |
Dye-sensitized selective photo-oxidation of cysteine.
Topics: Acetates; Amino Acids; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Coloring Agents; Cresols; Cysteine; Cystine; Egg White; Gentian Violet; Glutathione; Guanidines; Histidine; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Light; Mercaptoethanol; Methionine; Muramidase; Optical Rotation; Oxidation-Reduction; Peptides; Radiation Effects; Spectrophotometry; Structure-Activity Relationship; Sulfonic Acids; Tryptophan; Tyrosine; Ultraviolet Rays | 1969 |
Luminescence of the tryptophan and tyrosine residues of papain in solution.
Topics: Cold Temperature; Cysteine; Deuterium; Fluorescence; Glucose; Glycols; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Papain; Tryptophan; Tyrosine | 1970 |
Purity of amino acids.
Topics: Amino Acids; Arginine; Biological Assay; Cysteine; Histidine; Lysine; Methionine; Pediococcus; Streptococcus; Threonine; Tryptophan; Tyrosine | 1970 |
Tyrosine ligands to iron in hemerythrin.
Topics: Alkanes; Benzoates; Binding Sites; Blood Proteins; Cysteine; Iron; Kinetics; Mercury; Organometallic Compounds; Spectrophotometry; Spectrum Analysis; Tyrosine; Ultraviolet Rays | 1970 |
Molecular weight and amino acid composition of five-times-crystallized phosphoglucose isomerase from rabbit skeletal muscle.
Topics: Amides; Amino Acids; Animals; Barium; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Crystallization; Cysteine; Diffusion; Glucose-6-Phosphate Isomerase; Hydrochloric Acid; Hydroxides; Molecular Weight; Muscles; Nitrogen; Oxygen; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Ultracentrifugation; Viscosity | 1970 |
[Chorismate mutase from Claviceps. II. Activation and inhibition by analogues of the effectors tryptophan, phenylalanine and tyrosine].
Topics: Ascomycota; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cyclohexanecarboxylic Acids; Cysteine; Enzyme Activation; Histidine; Kinetics; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1970 |
Reaction of carbodiimides with protein sulfhydryl groups.
Topics: Alkylation; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Drug Stability; Imines; Lactoglobulins; Mercaptoethanol; Proteins; Serum Albumin, Bovine; Sulfhydryl Compounds; Tyrosine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Effects of amino acid analogs on growth and toxin of Staphylococcus aureus.
Topics: Amino Acids; Cysteine; Ethionine; Fluorine; Methionine; Nitriles; Phenylalanine; Staphylococcus; Tyrosine | 1970 |
The middle ultraviolet spectra of proteins. I. Studies on model compounds.
Topics: Amino Acids; Benzene; Cresols; Cysteine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indoles; Methionine; Phenols; Phenylalanine; Proteins; Spectrophotometry; Spectrum Analysis; Toluene; Tryptophan; Tyrosine; Ultraviolet Rays | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
The essential thiol group of arginine kinase from Homarus vulgaris muscle studied by difference spectrophotometry and N-ethyl-[1-14C] maleimide labelling.
Topics: Amino Acid Sequence; Animals; Arginine; Brain; Carbon Isotopes; Chemical Phenomena; Chemistry; Creatine Kinase; Crustacea; Cysteine; Ethylmaleimide; Glutathione; Models, Chemical; Muscles; Peptides; Phosphotransferases; Rabbits; Spectrophotometry; Sulfhydryl Compounds; Trypsin; Tyrosine | 1970 |
Lysine uptake in cultured Trypanosoma cruzi: interactions of competitive inhibitors.
Topics: Alanine; Animals; Biological Transport; Cysteine; Glycine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Trypanosoma; Tyrosine; Valine | 1970 |
The susceptibility of N-acetyl-S-alkyl- and N-acetyl-S-aryl-cysteine ethyl esters to chymotryptic hydrolysis.
Topics: Acetates; Alkanes; Amines; Animals; Benzene Derivatives; Butylamines; Caproates; Cattle; Chymotrypsin; Cysteine; Esters; Kinetics; Methionine; Pancreas; Phenylalanine; Tryptophan; Tyrosine; Valerates | 1970 |
Probing the topography of proteins in solution by photosensitized oxidation. Irradiation of nitrophenyl derivatives of ribonuclease A.
Topics: Amino Acids; Circular Dichroism; Cysteine; Dinitrophenols; Hydrogen-Ion Concentration; Oxidation-Reduction; Protein Conformation; Radiation Effects; Ribonucleases; Solutions; Spectrophotometry, Ultraviolet; Tyrosine; Ultraviolet Rays | 1970 |
Essential histidyl residues of octopine dehydrogenase.
Topics: Animals; Carbonates; Cysteine; Deuterium; Dicarboxylic Acids; Guanidines; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; L-Lactate Dehydrogenase; Mollusca; Muscles; Oxidoreductases; Spectrophotometry; Tyrosine | 1971 |
Cytochrome c peroxidase. 3. The amino acid composition of cytochrome c peroxidase of Baker's yeast.
Topics: Amino Acids; Ammonia; Chemical Phenomena; Chemistry; Cysteine; Cytochromes; Lysine; Molecular Weight; Peroxidases; Saccharomyces; Tryptophan; Tyrosine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Synthesis of "acetone-oxytocin" from an isopropylidene derivative of S-benzyl-L-cysteinyl-L-tyrosine.
Topics: Acetone; Chemical Phenomena; Chemistry; Cysteine; Oxytocin; Peptides; Tyrosine | 1968 |
Non-heme iron proteins. V. The amino acid sequence of rubredoxin from Peptostreptococcus elsdenii.
Topics: Amino Acid Sequence; Amino Acids; Bacteria; Bacterial Proteins; Chromatography; Chymotrypsin; Cysteine; Iron; Lysine; Peptococcus; Spectrum Analysis; Trypsin; Tryptophan; Tyrosine | 1968 |
Histochemistry of myelin. V. Trypsin-digestible and trypsin-resistant proteins.
Topics: Animals; Brain; Cysteine; Cystine; Histocytochemistry; Myelin Sheath; Nerve Tissue Proteins; Peptide Hydrolases; Rats; Sciatic Nerve; Trypsin; Tryptophan; Tyrosine | 1968 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
Kinetics of the photochemical addition of [35S] cysteine to polynucleotides and nucleic acids.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; DNA; Kinetics; Methionine; Polynucleotides; RNA; Saccharomyces; Serine; Sulfur Isotopes; Threonine; Thymus Gland; Tyrosine; Ultraviolet Rays | 1968 |
On the precursors of insulin molecules.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carbon Isotopes; Chromatography, Gel; Crystallization; Cysteine; Female; Glycine; Hypothermia, Induced; Insulin; Liver; Male; Methylthiouracil; Pancreas; Pancreatectomy; Peptide Biosynthesis; Peptides; Pregnancy; Protein Biosynthesis; Rats; Stimulation, Chemical; Sulfur Isotopes; Tyrosine | 1968 |
Proteolytic enzymes.
Topics: Amino Acid Sequence; Binding Sites; Carboxypeptidases; Chymotrypsin; Cysteine; Models, Structural; Papain; Peptide Hydrolases; Tyrosine; X-Ray Diffraction | 1968 |
Photochemical addition of amino acids to 14C-uracil.
Topics: Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; DNA; Phenylalanine; Proteins; Radiation Effects; Tyrosine; Ultraviolet Rays; Uracil | 1969 |
The state of amino acid residues in beta-lactoglobulin.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Electrochemistry; Genetic Variation; Goats; Homozygote; Hydrogen-Ion Concentration; Lactoglobulins; Milk; Models, Structural; Molecular Biology; Optical Rotatory Dispersion; Protein Denaturation; Solvents; Spectrophotometry; Spectrum Analysis; Tryptophan; Tyrosine; Ultracentrifugation | 1969 |
Structural studies on rabbit muscle glycerol 3-phosphate dehydrogenase and a comparison of chemical and physical determinations of its molecular weight.
Topics: Alkylation; Amino Acids; Animals; Arginine; Autoradiography; Bees; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Chymotrypsin; Cysteine; Glycerolphosphate Dehydrogenase; Histidine; Isomerases; Kinetics; Lysine; Molecular Weight; Muscles; Rabbits; Rats; Species Specificity; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation | 1969 |
Note on a selective test for the detection of sulphur amino acids.
Topics: Amino Acids; Cysteine; Cystine; Glutathione; Leucine; Methionine; Proline; Tyrosine | 1969 |
Determination of dinitrophenylamino acids in structural proteins by chromatography on nylon powder columns. I. The water-soluble dinitrophenylamino acids.
Topics: Amino Acids; Animals; Chromatography; Collagen; Cysteine; Dinitrophenols; Hair; Hydrogen-Ion Concentration; Lysine; Methods; Nylons; Proteins; Serine; Textiles; Tyrosine; Wool | 1969 |
Biosynthesis of insulin chains A and B.
Topics: Animals; Carbon Isotopes; Cysteine; Glycine; In Vitro Techniques; Insulin; Methylthiouracil; Pancreas; Radiometry; Rats; Serine; Sulfur Isotopes; Tyrosine | 1965 |
Genetic control of the uptake of amino acids in Neurospora.
Topics: Amino Acids; Arginine; Cysteine; Enzyme Repression; Enzymes; Genes; Histidine; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Tryptophan; Tyrosine; Valine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
Amino acid esters as inhibitors of growth and of aminoacyl transfer ribonucleic acid synthetases in Euglena and Astasia.
Topics: Alanine; Amino Acids; Antimetabolites; Aspartic Acid; Cysteine; Esters; Euglena; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Leucine; Ligases; Methionine; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Studies on actin-actin and actin-myosin interaction.
Topics: Amino Acids; Animals; Cysteine; Hydrogen Peroxide; Iodine; Iodoacetates; Methionine; Muscle Proteins; Nitrobenzenes; Nucleotides; Rabbits; Sulfhydryl Compounds; Tyrosine | 1967 |
Thiolysis of some dinitrophenyl derivatives of amino acids.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Dinitrophenols; Histidine; Mercaptoethanol; Spectrophotometry; Sulfhydryl Compounds; Tyrosine | 1967 |
5-OH-dopa, product of and substrate for tyrosinase.
Topics: Basidiomycota; Catechol Oxidase; Chromatography, High Pressure Liquid; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Monophenol Monooxygenase; Oxidation-Reduction; Substrate Specificity; Tyrosine | 1982 |
Protein-bound dopa and 5-S-cysteinyldopa in non-melanogenic tissues.
Topics: Animals; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Free Radicals; Indoles; Melanins; Melanoma; Mice; Mice, Inbred Strains; Monophenol Monooxygenase; Protein Binding; Rats; Rats, Inbred Strains; Tyrosine | 1983 |
Inactivation of human tyrosinase by cysteine. Protection by dopa and tyrosine.
Topics: Catalase; Catechol Oxidase; Cells, Cultured; Cysteine; Humans; In Vitro Techniques; Levodopa; Melanoma; Monophenol Monooxygenase; Superoxide Dismutase; Tyrosine | 1984 |
Advantages of ferric ferricyanide to detect certain peptides and proteins on chromatograms.
Topics: Animals; Cattle; Coloring Agents; Cysteine; Cytochrome c Group; Ferrocyanides; Horses; Myocardium; Serum Albumin, Bovine; Tryptophan; Tyrosine | 1982 |
Amino acids and obesity.
Topics: Amino Acids; Amino Acids, Branched-Chain; Appetite Depressants; Arginine; Aspartame; Cysteine; Humans; Obesity; Tryptophan; Tyrosine | 1984 |
Changes of serum amino acids in severely burned patients.
Topics: Adolescent; Adult; Amino Acids; Amino Acids, Branched-Chain; Burns; Cysteine; Female; Humans; Male; Methionine; Phenylalanine; Tyrosine; Urea | 1983 |
Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro.
Topics: Animals; Cells, Cultured; Cricetinae; Culture Media; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Drug Synergism; Fibroblasts; Glutathione; Humans; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Skin Neoplasms; Stimulation, Chemical; Tyrosine | 1982 |
The effect of cysteine on oxidation of tyrosine, dopa, and cysteinyldopas.
Topics: Ascorbic Acid; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathione; Monophenol Monooxygenase; Oxidation-Reduction; Stimulation, Chemical; Tyrosine | 1982 |
The radiation inactivation of glutamate dehydrogenase.
Topics: Binding Sites; Cysteine; Electrons; Enzyme Activation; Free Radicals; Gamma Rays; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; NAD; Pulse Radiolysis; Tryptophan; Tyrosine | 1983 |
Resonance energy transfer between cysteine-34, tryptophan-214, and tyrosine-411 of human serum albumin.
Topics: Circular Dichroism; Cysteine; Energy Transfer; Humans; Hydrogen-Ion Concentration; Kinetics; ortho-Aminobenzoates; Protease Inhibitors; Protein Conformation; Serum Albumin; Spectrophotometry; Tryptophan; Tyrosine | 1983 |
Chemical modification of cysteine and tyrosine residues in formyltetrahydrofolate synthetase from Clostridium thermoaceticum.
Topics: Adenosine Triphosphate; Aziridines; Chemical Phenomena; Chemistry; Clostridium; Cysteine; Dansyl Compounds; Disulfides; Fluoresceins; Folic Acid; Formate-Tetrahydrofolate Ligase; Ligases; Organomercury Compounds; Pyridines; Tetranitromethane; Tyrosine | 1982 |
Changes in the proteins of wool following treatment of sheep with epidermal growth factor.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Hair; Infusions, Parenteral; Male; Mice; Protein Biosynthesis; Proteins; Sheep; Sulfur; Time Factors; Tyrosine | 1982 |
Reaction of the adenine nucleotide analogue 5'-p-fluorosulfonylbenzoyl adenosine at distinct tyrosine and cysteine residues of rabbit muscle pyruvate kinase.
Topics: Adenosine; Affinity Labels; Animals; Cysteine; Dithiothreitol; Kinetics; Magnesium; Muscles; Pyruvate Kinase; Rabbits; Tyrosine | 1981 |
Electrochemical behaviour of proteins at graphite electrodes. I. Electrooxidation of proteins as a new probe of protein structure and reactions.
Topics: Animals; Cysteine; Cystine; Electrochemistry; Electrodes; Graphite; Oxidation-Reduction; Protein Conformation; Proteins; Tryptophan; Tyrosine | 1980 |
Formation of a hydrophobic cluster in denatured bovine pancreatic trypsin inhibitor.
Topics: Alanine; Amino Acid Sequence; Animals; Aprotinin; Cattle; Cloning, Molecular; Cysteine; Escherichia coli; Isoleucine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Denaturation; Protein Folding; Tyrosine; Water | 1994 |
Thioallyl compounds: potent inhibitors of cell proliferation.
Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; CDC2 Protein Kinase; Cell Division; Cells, Cultured; Cysteine; Endothelium, Vascular; Garlic; GTPase-Activating Proteins; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plants, Medicinal; Protein Tyrosine Phosphatases; Proteins; Rats; Tyrosine; Umbilical Veins | 1994 |
Mitogenic signaling of thrombin in mesangial cells: role of tyrosine phosphorylation.
Topics: Benzoquinones; Calcium; Cells, Cultured; Cysteine; DNA; Gene Expression; Genistein; Glomerular Mesangium; Humans; Immunoblotting; Inositol Phosphates; Isoflavones; Lactams, Macrocyclic; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Sulfur Radioisotopes; Thrombin; Tyrosine | 1994 |
A novel cystic fibrosis mutation, Y109C, in the first transmembrane domain of CFTR.
Topics: Adolescent; Chloride Channels; Cysteine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Primers; Exons; Female; Frameshift Mutation; Humans; Introns; Membrane Proteins; Point Mutation; Polymerase Chain Reaction; Tyrosine | 1994 |
Signaling-induced association of a tyrosine-phosphorylated 36-kDa protein with p50csk.
Topics: Animals; Antibodies; Blood Platelets; Cell Line; CSK Tyrosine-Protein Kinase; Cysteine; Glutathione Transferase; Humans; Immunoblotting; Kinetics; Leukemia, Erythroblastic, Acute; Methionine; Molecular Weight; Neoplasm Proteins; Oncogene Proteins, Viral; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Receptors, IgG; src-Family Kinases; Sulfur Radioisotopes; Tumor Cells, Cultured; Tyrosine | 1994 |
Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cell Line; Cysteine; Humans; Interleukin-3; Janus Kinase 2; Mice; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Somatotropin; Recombinant Proteins; Signal Transduction; Trans-Activators; Transcription Factors; Transfection; Tyrosine | 1995 |
Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2-A resolution.
Topics: Acid Phosphatase; Amino Acid Sequence; Animals; Arginine; Binding Sites; Cattle; Computer Graphics; Crystallography, X-Ray; Cysteine; Erythrocytes; Humans; Isoenzymes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Phosphotyrosine; Protein Folding; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Sequence Homology, Amino Acid; Tyrosine | 1994 |
Site-directed mutagenesis of tyrosine-71 to phenylalanine in Citrobacter freundii tyrosine phenol-lyase: evidence for dual roles of tyrosine-71 as a general acid catalyst in the reaction mechanism and in cofactor binding.
Topics: Base Sequence; Catalysis; Circular Dichroism; Citrobacter freundii; Cysteine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 1995 |
Phosphorescence lifetime of tryptophan in proteins.
Topics: Amino Acid Sequence; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanidine; Guanidines; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Luminescent Measurements; Molecular Sequence Data; Peptides; Protein Denaturation; Proteins; Tryptophan; Tyrosine; Viscosity | 1995 |
A novel mutation of the adrenocorticotropin receptor (ACTH-R) gene in a family with the syndrome of isolated glucocorticoid deficiency, but no ACTH-R abnormalities in two families with the triple A syndrome.
Topics: Adenine; Adolescent; Adult; Amino Acid Sequence; Base Sequence; Cell Membrane; Cysteine; DNA; DNA Primers; Female; Genes, Recessive; Genetic Carrier Screening; Genetic Diseases, Inborn; Glucocorticoids; Guanine; Homozygote; Humans; Male; Middle Aged; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Corticotropin; Syndrome; Tyrosine | 1995 |
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element.
Topics: Amino Acid Sequence; Binding Sites; Cells, Cultured; Cysteine; Disulfides; Extracellular Matrix; Glycine; Humans; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Receptors, Glycine; Serine; Strychnine; Taurine; Threonine; Tyrosine | 1995 |
A novel missense mutation (C522Y) is present in the beta-hexosaminidase beta-subunit gene of a Japanese patient with infantile Sandhoff disease.
Topics: Base Sequence; beta-N-Acetylhexosaminidases; Codon; Consanguinity; Conserved Sequence; Cysteine; DNA Mutational Analysis; Female; Fibroblasts; Fluorescent Antibody Technique; G(M2) Ganglioside; Humans; Infant; Japan; Molecular Sequence Data; Mutation; Protein Structure, Secondary; Sandhoff Disease; Tyrosine | 1995 |
Leader peptidase from Escherichia coli: overexpression, characterization, and inactivation by modification of tryptophan residues 300 and 310 with N-bromosuccinimide.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Bromosuccinimide; Cysteine; Endopeptidases; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Membrane Proteins; Molecular Sequence Data; Serine Endopeptidases; Tryptophan; Tyrosine | 1995 |
Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; Cysteine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Genetic Linkage; Humans; Insulin; Japan; Kinetics; Macromolecular Substances; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Polymerase Chain Reaction; Receptor, Insulin; Recombinant Proteins; Threonine; Transfection; Tyrosine | 1995 |
The role of Cys-17 in the pyridoxal 5'-phosphate inhibition of the bovine liver low M(r) phosphotyrosine protein phosphatase.
Topics: Animals; Binding, Competitive; Cattle; Cloning, Molecular; Cysteine; Escherichia coli; Kinetics; Liver; Mutagenesis, Site-Directed; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Schiff Bases; Spectrophotometry, Ultraviolet; Tyrosine | 1993 |
Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Binding Sites; Cysteine; ErbB Receptors; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphopeptides; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Type C Phospholipases; Tyrosine | 1993 |
Chemical modification and site-directed mutagenesis studies of rat 3-hydroxyisobutyrate dehydrogenase.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Rats; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1995 |
Disruption of conserved rhodopsin disulfide bond by Cys187Tyr mutation causes early and severe autosomal dominant retinitis pigmentosa.
Topics: Adolescent; Adult; Amino Acid Sequence; Base Sequence; Child; Cysteine; Dark Adaptation; Disulfides; DNA Primers; Electroretinography; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phenotype; Point Mutation; Retina; Retinitis Pigmentosa; Rhodopsin; Tyrosine; Visual Fields | 1995 |
Inhibition of ribonucleotide reductase by nitric oxide derived from thionitrites: reversible modifications of both subunits.
Topics: Adenocarcinoma; Animals; Cell Line; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Kinetics; Leukemia L1210; Macromolecular Substances; Mice; Nitric Oxide; Nitrites; Ribonucleotide Reductases; Spectrophotometry; Tumor Cells, Cultured; Tyrosine | 1995 |
Peroxynitrite-mediated oxidative protein modifications.
Topics: Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Hydrogen-Ion Concentration; Male; Nitrates; Oxidation-Reduction; Oxidative Stress; Phenylhydrazines; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Tryptophan; Tyrosine | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the internalization of the rat neurotensin receptor.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line; Cysteine; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Neurotensin; Threonine; Tyrosine | 1995 |
Identification of the Cys634-->Tyr mutation of the RET proto-oncogene in a pedigree with multiple endocrine neoplasia type 2A and localized cutaneous lichen amyloidosis.
Topics: Amyloidosis; Base Sequence; Cysteine; Exons; Genetic Carrier Screening; Humans; Lichen Planus; Molecular Sequence Data; Multiple Endocrine Neoplasia; Mutation; Pedigree; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogenes; Tyrosine | 1994 |
Effects of the micro-environment on the photophysical properties of hematoporphyrin.
Topics: Cysteine; DEAE-Dextran; Hematoporphyrins; Histidine; Photochemistry; Photochemotherapy; Povidone; Silicon Dioxide; Tyrosine | 1994 |
Mechanism-based inhibition of thymidylate synthase by 5-(trifluoromethyl)-2'-deoxyuridine 5'-monophosphate.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, Gel; Chromatography, High Pressure Liquid; Collodion; Crystallization; Crystallography, X-Ray; Cysteine; Dithiothreitol; Fluorides; Lacticaseibacillus casei; Mass Spectrometry; Mercaptoethanol; Models, Molecular; Molecular Sequence Data; Molecular Structure; Spectrophotometry, Ultraviolet; Thymidylate Synthase; Thymine Nucleotides; Tyrosine | 1994 |
Molecular basis of maple syrup urine disease: novel mutations at the E1 alpha locus that impair E1(alpha 2 beta 2) assembly or decrease steady-state E1 alpha mRNA levels of branched-chain alpha-keto acid dehydrogenase complex.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Base Sequence; Cysteine; DNA Mutational Analysis; DNA Primers; Female; Fibroblasts; Humans; Infant; Ketone Oxidoreductases; Male; Maple Syrup Urine Disease; Molecular Sequence Data; Multienzyme Complexes; Mutation; Oligonucleotide Probes; Point Mutation; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Deletion; Transfection; Tyrosine | 1994 |
Interaction of mammalian sperm nuclear protamines and peptides derived thereof with immobilized zinc.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Chromatography, Affinity; Cysteine; Histidine; Humans; Male; Molecular Sequence Data; Peptides; Protamines; Serine; Sheep; Spermatozoa; Swine; Tyrosine; Zinc | 1994 |
Direct colorimetric determination of solid-supported functional groups and ligands using bicinchoninic acid.
Topics: Aldehydes; Amino Acids; Carboxylic Acids; Colorimetry; Cysteine; Hydrazines; Indicators and Reagents; Ligands; Quinolines; Sulfhydryl Compounds; Thyroxine; Tyrosine | 1994 |
Tyr-341 of the beta subunit is a major Km-determining residue of TF1-ATPase: parallel effect of its mutations on Kd(ATP) of the beta subunit and on Km(ATP) of the alpha 3 beta 3 gamma complex.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Binding Sites; Calorimetry; Catalysis; Circular Dichroism; Cysteine; Kinetics; Molecular Sequence Data; Mutation; Peptide Fragments; Proton-Translocating ATPases; Thermodynamics; Titrimetry; Tyrosine | 1994 |
Determination of the pKa values of active-center cysteines, cysteines-32 and -35, in Escherichia coli thioredoxin by Raman spectroscopy.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Solutions; Spectrum Analysis, Raman; Thioredoxins; Tryptophan; Tyrosine | 1993 |
Inactivation of oncoprotein binding by a single Cys706-to-Tyr substitution in the retinoblastoma protein.
Topics: Adenovirus E1A Proteins; Antigens, Polyomavirus Transforming; Base Sequence; Cysteine; DNA Primers; Genes, Retinoblastoma; Glutathione; Humans; Molecular Sequence Data; Protein Binding; Recombinant Fusion Proteins; Retinoblastoma; Retinoblastoma Protein; Tyrosine | 1994 |
Overexpression and mutagenesis of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase. Role of cysteines and tyrosines in catalysis.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Base Sequence; Catalysis; Cloning, Molecular; Cysteine; DNA, Complementary; Escherichia coli; Indomethacin; Kinetics; Liver; Molecular Sequence Data; Mutagenesis; Rats; Tyrosine | 1994 |
Glutamine force-feeding effect on plasma amino-acid concentrations in growing rats fed a cafeteria diet.
Topics: Aging; Amino Acids; Animals; Cysteine; Diet; Glutamine; Ornithine; Proline; Rats; Rats, Wistar; Threonine; Tyrosine | 1994 |
Oxidation of biologic molecules by ozone: the effect of pH.
Topics: Albumins; Ascorbic Acid; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Oxidation-Reduction; Ozone; Spectrometry, Fluorescence; Tyrosine; Uric Acid | 1993 |
Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate.
Topics: Azides; Cysteine; Deoxyuracil Nucleotides; Deuterium; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Models, Chemical; Mutation; Nitrogen; Ribonucleotide Reductases; Spin Labels; Tyrosine | 1993 |
Probing weakly polar interactions in cytochrome c.
Topics: Cysteine; Cytochrome c Group; Cytochromes c; Guanidine; Guanidines; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Denaturation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thermodynamics; Tyrosine | 1993 |
Two new candidate mutations in type IIA von Willebrand's disease (Arg834-->Gly, Gly846-->Arg) and one polymorphism (Tyr821-->Cys) in the A2 region of the von Willebrand factor.
Topics: Adolescent; Adult; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Child; Cysteine; DNA; Female; Genetic Markers; Glycine; Humans; Male; Molecular Sequence Data; Oligodeoxyribonucleotides; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Tyrosine; von Willebrand Diseases; von Willebrand Factor | 1993 |
Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase.
Topics: Benzene Derivatives; Binding Sites; Catalase; Chloride Peroxidase; Cysteine; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Heme; Histidine; Humans; Iron; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Myoglobin; Spectrophotometry; Spectrum Analysis, Raman; Tyrosine | 1993 |
Reduction of cytochrome C by fragments of heat shock protein 70.
Topics: Amino Acid Sequence; Cysteine; Cytochrome c Group; Heat-Shock Proteins; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Spectrophotometry; Tyrosine | 1993 |
Arthrobacter D-xylose isomerase: protein-engineered subunit interfaces.
Topics: Aldose-Ketose Isomerases; Arthrobacter; Base Sequence; Binding Sites; Carbohydrate Epimerases; Cysteine; Disulfides; Enzyme Stability; Hot Temperature; Hydrogen-Ion Concentration; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Protein Denaturation; Protein Engineering; Tyrosine; X-Ray Diffraction | 1993 |
Cation binding and conformation of human calmodulin-like protein.
Topics: Allosteric Regulation; Calcium; Calcium-Binding Proteins; Calmodulin; Cysteine; Humans; Magnesium; Models, Chemical; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrum Analysis; Tyrosine | 1993 |
From RNA to DNA, why so many ribonucleotide reductases?
Topics: Allosteric Regulation; Amino Acid Sequence; Anaerobiosis; Biological Evolution; Cobamides; Cysteine; Escherichia coli; Iron; Lactobacillus; Molecular Sequence Data; Oxidation-Reduction; Ribonucleotide Reductases; Ribonucleotides; Substrate Specificity; Tyrosine | 1993 |
The natural mutation Y248C of human angiotensinogen leads to abnormal glycosylation and altered immunological recognition of the protein.
Topics: Amino Acid Sequence; Angiotensinogen; Base Sequence; Cysteine; Female; Genetic Carrier Screening; Genetic Variation; Glycoside Hydrolases; Glycosylation; Humans; Hypertension; Immunoradiometric Assay; Male; Molecular Sequence Data; Oligodeoxyribonucleotides; Pedigree; Point Mutation; Radioimmunoassay; Recombinant Proteins; Tyrosine | 1996 |
Tyrosine-272 is involved in the inhibition of protein phosphatase-1 by multiple toxins.
Topics: Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Drug Resistance; Enzyme Inhibitors; Ethers, Cyclic; Molecular Sequence Data; Okadaic Acid; Phosphoprotein Phosphatases; Protein Binding; Protein Phosphatase 1; Structure-Activity Relationship; Toxins, Biological; Tyrosine | 1996 |
Somatic mutations of the ret protooncogene in sporadic medullary thyroid carcinoma are not restricted to exon 16 and are associated with tumor recurrence.
Topics: Adult; Aged; Amino Acid Sequence; Base Sequence; Calcitonin; Carcinoma, Medullary; Cysteine; DNA; DNA Primers; DNA, Neoplasm; Drosophila Proteins; Exons; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Point Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Recurrence; Restriction Mapping; Thyroid Neoplasms; Tyrosine | 1996 |
Alteration in the conformational stability of collagen caused by the incorporation of the lysine analogue S-2-aminoethylcysteine.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Chick Embryo; Chromatography, Agarose; Collagen; Cysteine; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Hydroxylation; Kinetics; Lysine; Molecular Structure; Pepsin A; Proline; Protein Conformation; Protein Synthesis Inhibitors; RNA, Transfer, Lys; Transfer RNA Aminoacylation; Tyrosine | 1996 |
Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C.
Topics: 3T3 Cells; Animals; CHO Cells; Cricetinae; Cysteine; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Mice; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Terpenes; Thapsigargin; Tyrosine | 1996 |
Radiological and histological variants of thanatophoric dysplasia are associated with common mutations in FGFR-3.
Topics: Adult; Arginine; Bone and Bones; Cartilage; Cysteine; Diagnosis, Differential; Female; Fetus; Genetic Variation; Gestational Age; Humans; Infant, Newborn; Phenotype; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pregnancy; Protein-Tyrosine Kinases; Radiography; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Thanatophoric Dysplasia; Tyrosine | 1996 |
A second independent Tyr168Cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy.
Topics: Adult; Austria; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 22; Cysteine; DNA Primers; Exons; Female; Fundus Oculi; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proteins; Retinal Diseases; Tissue Inhibitor of Metalloproteinase-3; Tyrosine | 1996 |
Steric constraints in the recognition of peptide substrates for the epidermal growth factor receptor kinase.
Topics: Binding Sites; Cysteine; Epidermal Growth Factor; ErbB Receptors; Fluoresceins; Fluorescent Dyes; Iodoacetamide; Kinetics; Mass Spectrometry; Molecular Weight; Oligopeptides; Phosphorylation; Protein Conformation; Signal Transduction; Substrate Specificity; Tyrosine | 1996 |
Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation.
Topics: Animals; Apoptosis; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Cysteine; Cytoskeleton; Dizocilpine Maleate; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Nitric Oxide; Penicillamine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Tyrosine | 1996 |
A point mutation in glycoprotein IX coding sequence (Cys73 (TGT) to Tyr(TAT)) causes impaired surface expression of GPIb/IX/V complex in two families with Bernard-Soulier syndrome.
Topics: Adult; Bernard-Soulier Syndrome; Blood Platelets; Cysteine; Female; Humans; Male; Middle Aged; Platelet Glycoprotein GPIb-IX Complex; Point Mutation; Tyrosine | 1996 |
Carbonyl reducing 17 beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Androstenedione; Ascomycota; Binding Sites; Binding, Competitive; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydroxysteroid Dehydrogenases; Immunoblotting; Kinetics; Lysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tetranitromethane; Trinitrobenzenesulfonic Acid; Tyrosine; Vitamin K | 1997 |
Structural and functional aspects of rat microsomal glutathione transferase. The roles of cysteine 49, arginine 107, lysine 67, histidine, and tyrosine residues.
Topics: Amino Acid Sequence; Animals; Arginine; Cysteine; Enzyme Inhibitors; Glutathione Transferase; Histidine; Indicators and Reagents; Lysine; Male; Microsomes, Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylglyoxal; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid; Tyrosine | 1997 |
Mutation analysis of the HLA-H gene in Italian hemochromatosis patients.
Topics: Chromosomes, Human, Pair 6; Cysteine; Female; Genetic Heterogeneity; Genetic Linkage; Haplotypes; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Italy; Major Histocompatibility Complex; Male; Membrane Proteins; Mutation; Polymorphism, Single-Stranded Conformational; Sequence Analysis, DNA; Tyrosine; White People | 1997 |
Strategies for handling polypeptides on a microscale.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Microchemistry; Molecular Sequence Data; Peptides; Proteins; Sequence Analysis; Specimen Handling; Tryptophan; Tyrosine | 1997 |
The conserved residue tyrosine 34 is essential for maximal activity of iron-superoxide dismutase from Escherichia coli.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Restriction Mapping; Serine; Structure-Activity Relationship; Superoxide Dismutase; Tyrosine | 1997 |
Rapid diagnosis of the HLA-H gene Cys 282 Tyr mutation in hemochromatosis by polymerase chain reaction--a very rare mutation in the Chinese population.
Topics: Base Sequence; China; Cysteine; DNA Primers; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Polymerase Chain Reaction; Tyrosine | 1997 |
Compound heterozygosity for two novel missense mutations in the prothrombin gene in a patient with a severe bleeding tendency.
Topics: Blood Coagulation Factors; Cysteine; Female; Genetic Predisposition to Disease; Genetic Variation; Hemorrhage; Heterozygote; Humans; Hypoprothrombinemias; Infant, Newborn; Point Mutation; Prothrombin; Reference Values; Sequence Analysis, DNA; Tryptophan; Tyrosine | 1997 |
Unexpected lability of cysteine acetamidomethyl thiol protecting group. Tyrosine ring alkylation and disulfide bond formation upon acidolysis.
Topics: Alkylation; Amino Acid Sequence; Cysteine; Disulfides; Dithionitrobenzoic Acid; Drug Stability; Oligopeptides; Peptides, Cyclic; Resins, Plant; Sulfhydryl Compounds; Tyrosine | 1997 |
Signal transduction via the CD38/NAD+ glycohydrolase.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Aplysia; Binding Sites; Catalysis; Cell Line; COS Cells; Cysteine; Epitope Mapping; HL-60 Cells; Humans; Membrane Glycoproteins; Monocytes; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Superoxides; Tyrosine; Ubiquitin-Protein Ligases | 1997 |
Genetic and clinical description of hemochromatosis probands and heterozygotes: evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis.
Topics: Adult; Alleles; Aspartic Acid; Chromosomes, Human, Pair 6; Cysteine; Female; Gene Frequency; Genes, MHC Class I; Genetic Linkage; Hemochromatosis; Heterozygote; Histidine; Histocompatibility Testing; HLA Antigens; Homozygote; Humans; Iron; Male; Middle Aged; Mutation; Tyrosine; White People | 1997 |
The role of cysteine residues in the homeodomain protein Mat alpha 2 in mating-type control of Saccharomyces cerevisiae.
Topics: Cysteine; Dimerization; Fungal Proteins; Homeodomain Proteins; Mutation; Receptors, Mating Factor; Receptors, Peptide; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Sulfides; Transcription Factors; Transformation, Genetic; Tyrosine | 1997 |
Properties of electrochemically active components in mammalian vitreous humor.
Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Circadian Rhythm; Cysteine; Glutathione; Rabbits; Rats; Tyrosine; Uric Acid; Vitreous Body | 1997 |
A single mutation at the catalytic site of TF1-alpha3beta3gamma complex switches the kinetics of ATP hydrolysis from negative to positive cooperativity.
Topics: Adenosine Triphosphate; Alanine; Binding Sites; Catalysis; Cysteine; Dose-Response Relationship, Drug; Hydrolysis; Kinetics; Leucine; Mathematics; Mutation; Proton-Translocating ATPases; Tyrosine | 1997 |
Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bone Morphogenetic Proteins; Conserved Sequence; COS Cells; Cysteine; Dwarfism; Female; Fingers; Genes, Dominant; Genes, Recessive; Growth Differentiation Factor 5; Growth Substances; Hand Deformities, Congenital; Heterozygote; Humans; Male; Morphogenesis; Osteochondrodysplasias; Pedigree; Point Mutation; Recombinant Proteins; Transfection; Tyrosine | 1997 |
Homozygosity for the predominant Cys282Tyr mutation and absence of disease expression in hereditary haemochromatosis.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Iron; Liver; Male; Membrane Proteins; Middle Aged; Mutation; Pedigree; Transferrin; Tyrosine | 1997 |
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding.
Topics: Asparagine; Binding Sites; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tyrosine | 1997 |
Correcting the circular dichroism spectra of peptides for contributions of absorbing side chains.
Topics: Amino Acid Sequence; Circular Dichroism; Cysteine; Methionine; Molecular Sequence Data; Peptides; Phenylalanine; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1997 |
Chemical characterization of pheomelanogenesis starting from dihydroxyphenylalanine or tyrosine and cysteine. Effects of tyrosinase and cysteine concentrations and reaction time.
Topics: Cysteine; Dihydroxyphenylalanine; Kinetics; Melanins; Models, Chemical; Monophenol Monooxygenase; Tyrosine | 1997 |
Rapid diagnosis of asymptomatic hereditary haemochromatosis by detection of the Cys282Tyr mutation in the HLA-H gene.
Topics: Cysteine; DNA Mutational Analysis; Female; Genes, MHC Class I; Hemochromatosis; Humans; Middle Aged; Mutation; Polymerase Chain Reaction; Tyrosine | 1997 |
Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins.
Topics: Amino Acids; Animals; Biotinylation; Cell Membrane; Cysteine; Glycosylation; Immunodominant Epitopes; Iodine Radioisotopes; Lysine; Membrane Proteins; Mice; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Receptors, Nicotinic; Tyrosine; Xenopus laevis | 1997 |
Melanogenesis in cultured melanocytes can be substantially influenced by L-tyrosine and L-cysteine.
Topics: Cells, Cultured; Culture Media; Cysteine; Humans; Melanins; Melanocytes; Pigmentation; Tyrosine | 1997 |
Molecular analysis of HLA-H gene mutations in New Zealand patients with haemochromatosis.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Male; Membrane Proteins; Middle Aged; Mutation; New Zealand; Polymerase Chain Reaction; Restriction Mapping; Tyrosine | 1997 |
Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease.
Topics: Binding Sites; Cysteine; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Endonucleases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis; Structure-Activity Relationship; Tyrosine; Vaccinia virus | 1998 |
Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors.
Topics: Amino Acid Sequence; Animals; Cell Line; Cysteine; Dimerization; Disulfides; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin; Receptors, Interleukin-3; Receptors, Interleukin-5; Sequence Homology, Amino Acid; Tyrosine | 1998 |
Mutations in the nucleotide binding domain of the alpha subunits of the F1-ATPase from thermophilic Bacillus PS3 that affect cross-talk between nucleotide binding sites.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Arginine; Bacillus; Bacterial Proteins; Binding Sites; Cysteine; Fluorine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Proton-Translocating ATPases; Structure-Activity Relationship; Tyrosine | 1998 |
Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues.
Topics: Crystallography, X-Ray; Cysteine; Enzyme Activation; Humans; Immunoblotting; Manganese; Models, Molecular; Nitrates; Oxidation-Reduction; Protein Binding; Superoxide Dismutase; Tyrosine | 1998 |
A cysteine-rich isoform of neuregulin controls the level of expression of neuronal nicotinic receptor channels during synaptogenesis.
Topics: Acetylcholine; Alternative Splicing; Amino Acid Sequence; Animals; Antineoplastic Agents; Axons; Chick Embryo; Culture Media, Conditioned; Cysteine; DNA, Complementary; Gene Expression Regulation, Developmental; Glycoproteins; Isomerism; Molecular Sequence Data; Motor Neurons; Nerve Growth Factors; Neuregulins; Phosphorylation; Presynaptic Terminals; Receptors, Nicotinic; Recombinant Proteins; Spinal Cord; Sympathetic Nervous System; Tyrosine; Up-Regulation; Viscera | 1998 |
A PCR-SSP method for detecting the Cys282Tyr mutation in the HFE gene associated with hereditary haemochromatosis.
Topics: Cysteine; DNA Primers; Hemochromatosis; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Tyrosine | 1997 |
Identification of histidine residues in the sugar binding site of snake gourd (Trichosanthes anguina) seed lectin.
Topics: Binding Sites; Cysteine; Galactose; Histidine; Imidazoles; Lectins; Lysine; Plant Lectins; Plant Proteins; Seeds; Tryptophan; Tyrosine | 1998 |
Investigation of the potential active site of a cyanide dihydratase using site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding Sites; Cysteine; Hydrolases; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Pseudomonas; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Tyrosine | 1998 |
Loss of conformational stability in calmodulin upon methionine oxidation.
Topics: Amino Acid Sequence; Animals; Calmodulin; Calorimetry; Cattle; Circular Dichroism; Cysteine; Hydrogen Peroxide; Methionine; Models, Chemical; Models, Molecular; Oxidation-Reduction; Plants; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Spectrometry, Mass, Secondary Ion; Thermodynamics; Triticum; Tyrosine | 1998 |
The bldD gene of Streptomyces coelicolor A3(2): a regulatory gene involved in morphogenesis and antibiotic production.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Bacteriophages; Base Sequence; Blotting, Northern; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Codon, Initiator; Cysteine; DNA-Binding Proteins; DNA, Bacterial; Gene Expression; Gene Library; Genetic Complementation Test; Molecular Sequence Data; Open Reading Frames; Plasmids; Point Mutation; Promoter Regions, Genetic; Protein Biosynthesis; Recombination, Genetic; RNA, Bacterial; Sequence Alignment; Sequence Homology, Amino Acid; Single-Strand Specific DNA and RNA Endonucleases; Spores, Bacterial; Streptomyces; Transcription Factors; Transcription, Genetic; Tyrosine | 1998 |
Tear fluid content of electrochemically active components including water soluble antioxidants.
Topics: Adult; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Tears; Tyrosine; Uric Acid | 1998 |
HFE codon 63/282 (H63D/C282Y) dimorphism in German patients with genetic hemochromatosis.
Topics: Aspartic Acid; Codon; Cysteine; Female; Genotype; Germany; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Point Mutation; Polymorphism, Genetic; Tyrosine | 1998 |
Aberrant intermolecular disulfide bonding in a mutant HLA-DM molecule: implications for assembly, maturation, and function.
Topics: Antigens, Differentiation, B-Lymphocyte; Biological Transport; Cell Line; Cysteine; Dimerization; Disulfides; DNA, Complementary; Histocompatibility Antigens Class II; HLA-D Antigens; HLA-DR3 Antigen; Humans; Mutagenesis, Site-Directed; Peptides; Point Mutation; Protein Binding; Sequence Analysis, DNA; Transfection; Tyrosine | 1998 |
Ca2+ and Zn2+ bind to different sites and induce different conformational changes in human calcyclin.
Topics: Base Sequence; Binding Sites; Calcium; Calcium-Binding Proteins; Cell Cycle Proteins; Cysteine; DNA Primers; Escherichia coli; Humans; In Vitro Techniques; Kinetics; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; S100 Calcium Binding Protein A6; S100 Proteins; Spectrometry, Fluorescence; Sulfhydryl Compounds; Tyrosine; Zinc | 1998 |
[Development of targeted chemoradiotherapy for malignant melanoma by exploitation of metabolic pathway].
Topics: Animals; Antineoplastic Agents; Cysteamine; Cysteine; DNA Damage; Humans; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oxidative Stress; Phenols; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1998 |
Involvement of tyrosine phosphorylation in inhibition of fMLP-induced PLD activation by N-acetyl-L-cysteine in differentiated HL60 cells.
Topics: Acetylcysteine; Androstadienes; Cell Differentiation; Chelating Agents; Cysteine; Dithiothreitol; Enzyme Activation; Free Radical Scavengers; HL-60 Cells; Humans; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Sulfhydryl Reagents; Tyrosine; Unithiol; Wortmannin | 1998 |
Rapid diagnostic test for detection of Cys282Tyr mutation in hereditary hemochromatosis.
Topics: Cysteine; DNA Primers; Hemochromatosis; Histocompatibility Antigens Class I; HLA Antigens; Humans; Mutation; Polymerase Chain Reaction; Tyrosine | 1998 |
Protective protein/cathepsin A loss in cultured cells derived from an early-infantile form of galactosialidosis patients homozygous for the A1184-G transition (Y395C mutation).
Topics: Amino Acid Substitution; Antibodies; Carboxypeptidases; Cathepsin A; Cells, Cultured; Cysteine; Female; Fluorescent Antibody Technique, Indirect; Genotype; Homozygote; Humans; Immunoblotting; Infant; Lysosomal Storage Diseases; Lysosomes; Male; Pedigree; Point Mutation; Tyrosine | 1998 |
C282Y mutation in HFE (haemochromatosis) gene and type 2 diabetes.
Topics: Adult; Codon; Cysteine; Diabetes Mellitus, Type 2; England; Female; Genetic Predisposition to Disease; Genetic Testing; Hemochromatosis; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Prevalence; Tyrosine | 1998 |
Information from the water stripe in TOCSY experiments on systems with exchangeable protons.
Topics: Amino Acids; Carbon; Cysteine; Electron Spin Resonance Spectroscopy; Hydrogen; Hydroxyl Radical; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Nitrogen; Peptides; Protons; Solvents; Sucrose; Threonine; Time Factors; Tyrosine; Water | 1998 |
A novel type II complement C2 deficiency allele in an African-American family.
Topics: Alleles; Amino Acid Substitution; Black People; Child; Complement C2; Cysteine; Exons; Glycine; Humans; Male; Mutation; Pedigree; Polymorphism, Genetic; Protein Biosynthesis; Tyrosine | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Reference Values; Tyrosine | 1998 |
Chemical modification of barley root oxalate oxidase shows the presence of a lysine, a carboxylate, and disulfides, essential for enzyme activity.
Topics: Arginine; Carboxylic Acids; Cysteine; Disulfides; Enzyme Activation; Histidine; Hordeum; Lysine; Metals; Oxidoreductases; Plant Roots; Protein Binding; Tyrosine | 1998 |
Several noncontiguous domains of CDK4 are involved in binding to the P16 tumor suppressor protein.
Topics: Arginine; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Cysteine; Glutathione Transferase; Humans; Melanoma; Mutagenesis, Site-Directed; Mutation; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Structure-Activity Relationship; Tyrosine | 1998 |
Frequency of the HFE C282Y and H63D mutations in distinct ethnic groups living in Spain.
Topics: Alleles; Aspartic Acid; Cysteine; Ethnicity; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Roma; Spain; Tyrosine | 1998 |
Mapping of the DNA binding domain of the copper-responsive transcription factor Mac1 from Saccharomyces cerevisiae.
Topics: Amino Acid Substitution; Base Sequence; Binding Sites; Cloning, Molecular; Copper; Cysteine; Escherichia coli; Fungal Proteins; Genetic Complementation Test; Mutagenesis, Site-Directed; Nuclear Proteins; Oligodeoxyribonucleotides; Oligonucleotide Probes; Promoter Regions, Genetic; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Tyrosine; Zinc | 1998 |
LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Carrier Proteins; Cysteine; Glycolipids; Humans; Jurkat Cells; Lymphocyte Activation; Membrane Proteins; Mutation; Palmitates; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Signal Transduction; T-Lymphocytes; Tyrosine | 1998 |
Plasma amino acids in anorexia nervosa.
Topics: Adolescent; Amino Acids; Anorexia Nervosa; Carnitine; Chromatography, Ion Exchange; Cysteine; Female; Glycine; Humans; Insulin-Like Growth Factor I; Methionine; Phenylalanine; Reference Values; Tyrosine; Valine | 1998 |
Valine 904, tyrosine 898, and cysteine 908 in Na,K-ATPase alpha subunits are important for assembly with beta subunits.
Topics: Animals; Cysteine; Enzyme Stability; Hot Temperature; Mutagenesis, Site-Directed; Ouabain; Protein Binding; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Tyrosine; Valine | 1998 |
Water soluble antioxidants in mammalian aqueous humor: interaction with UV B and hydrogen peroxide.
Topics: Aged; Analysis of Variance; Animals; Antioxidants; Aqueous Humor; Ascorbic Acid; Cataract; Chromatography, High Pressure Liquid; Cysteine; Disease Models, Animal; Female; Glutathione; Humans; Hydrogen Peroxide; Mammals; Oxidants; Rabbits; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine; Ultraviolet Rays; Uric Acid | 1998 |
Non-C282Y familial iron overload: evidence for locus heterogeneity in haemochromatosis.
Topics: Adult; Amino Acid Substitution; Cysteine; Female; Genetic Diseases, Inborn; Genetic Heterogeneity; Hemochromatosis; Humans; Iron Overload; Male; Middle Aged; Tyrosine | 1998 |
Thanatophoric dysplasia type I with syndactyly.
Topics: Cysteine; Fetal Diseases; Humans; Male; Point Mutation; Protein-Tyrosine Kinases; Radiography; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Syndactyly; Thanatophoric Dysplasia; Tyrosine | 1998 |
Novel missense mutation resulting in the substitution of tyrosine by cysteine at codon 597 of the type X collagen gene associated with Schmid metaphyseal chondrodysplasia.
Topics: Adult; Amino Acid Substitution; Codon; Collagen; Cysteine; DNA; DNA Mutational Analysis; Female; Humans; Mutation, Missense; Osteochondrodysplasias; Pedigree; Polymerase Chain Reaction; Tyrosine | 1998 |
Are His63Asp or Cys282Tyr HFE mutations associated with porphyria cutanea tarda? Data of patients from central and southern Italy.
Topics: Asparagine; Cysteine; Histidine; Humans; Italy; Point Mutation; Porphyria Cutanea Tarda; Tyrosine | 1998 |
Evidence for kinetic intermediate states during the refolding of GdnHCl-denatured MM-creatine kinase. Characterization of a trapped monomeric species.
Topics: Anilino Naphthalenesulfonates; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Creatine Kinase; Cysteine; Enzyme Activation; Guanidine; Isoenzymes; Kinetics; Models, Chemical; Protein Binding; Protein Denaturation; Protein Folding; Rabbits; Spectrometry, Fluorescence; Titrimetry; Tryptophan; Tyrosine | 1998 |
High incidence of the Cys 282 Tyr mutation in the HFE gene in the Irish population--implications for haemochromatosis.
Topics: Cysteine; Genes, MHC Class I; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Humans; Incidence; Ireland; Membrane Proteins; Point Mutation; Tyrosine | 1998 |
Dysfunctional glucocorticoid receptor with a single point mutation ablates the CCAAT/enhancer binding protein-dependent growth suppression response in a steroid-resistant rat hepatoma cell variant.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Division; Cysteine; Dexamethasone; DNA; DNA-Binding Proteins; Gene Expression Regulation; Glucocorticoids; Mutagenesis, Site-Directed; Nuclear Proteins; Orosomucoid; Point Mutation; Promoter Regions, Genetic; Rats; Receptors, Glucocorticoid; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Zinc Fingers | 1999 |
Patients with type 2 diabetes have a high frequency of the C282Y mutation of the hemochromatosis gene.
Topics: Adolescent; Adult; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Hemochromatosis; Humans; Male; Middle Aged; Point Mutation; Tyrosine | 1998 |
Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride: evidence for a novel disulfide exchange reaction in a covalently cross-linked mutant.
Topics: Animals; Chromatography, Gel; Circular Dichroism; Cross-Linking Reagents; Cysteine; Disulfides; Guanidine; Models, Molecular; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Conformation; Protein Denaturation; Recombinant Proteins; Spectrometry, Fluorescence; Triose-Phosphate Isomerase; Tryptophan; Tyrosine; Urea | 1999 |
Cavity-creating mutation at the dimer interface of Plasmodium falciparum triosephosphate isomerase: restoration of stability by disulfide cross-linking of subunits.
Topics: Animals; Chemical Precipitation; Circular Dichroism; Computer Simulation; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Enzyme Activation; Enzyme Stability; Models, Molecular; Mutagenesis, Site-Directed; Plasmodium falciparum; Protein Engineering; Recombinant Proteins; Triose-Phosphate Isomerase; Tyrosine | 1999 |
Structural and functional analysis of the protein products derived from mutant fur alleles in an endoprotease-deficient Chinese hamster ovary cell strain.
Topics: Alleles; Animals; CHO Cells; Cricetinae; Cysteine; Furin; Glycosylation; Mutation; Protein Processing, Post-Translational; RNA Splicing; Subtilisins; Transfection; Tyrosine | 1998 |
Expression of apolipoprotein(a) kringle IV type 9 in Escherichia coli: demonstration of a specific interaction between kringle IV type 9 and apolipoproteinB-100.
Topics: Amino Acid Sequence; Apolipoprotein B-100; Apolipoproteins A; Apolipoproteins B; Binding Sites; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Gene Expression; Humans; Kringles; Lipoproteins, LDL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Folding; Tyrosine | 1998 |
Interactions between human cyclin T, Tat, and the transactivation response element (TAR) are disrupted by a cysteine to tyrosine substitution found in mouse cyclin T.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chloramphenicol O-Acetyltransferase; CHO Cells; Cricetinae; Cyclin T; Cyclins; Cysteine; Gene Products, tat; HIV Long Terminal Repeat; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tyrosine | 1999 |
A novel endogenous inhibitor of phenoloxidase from Musca domestica has a cystine motif commonly found in snail and spider toxins.
Topics: Amino Acid Sequence; Animals; Computer Simulation; Cysteine; Cystine; Disulfides; Enzyme Inhibitors; Houseflies; Hydrolysis; Insect Proteins; Intercellular Signaling Peptides and Proteins; Models, Molecular; Molecular Sequence Data; Mollusk Venoms; Monophenol Monooxygenase; Peptide Fragments; Peptides; Phosphines; Serine Endopeptidases; Solubility; Spider Venoms; Tyrosine; Water | 1999 |
Replacement of the proximal histidine iron ligand by a cysteine or tyrosine converts heme oxygenase to an oxidase.
Topics: Amino Acid Substitution; Catalysis; Cysteine; Electron Transport; Ferric Compounds; Ferrous Compounds; Heme; Heme Oxygenase (Decyclizing); Histidine; Humans; Iron; Ligands; Mutagenesis; Oxidation-Reduction; Oxidoreductases; Peroxides; Spectrum Analysis, Raman; Tyrosine | 1999 |
Cysteine transport in melanosomes from murine melanocytes.
Topics: Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Cysteine; Glutathione; Melanins; Melanocytes; Melanosomes; Mice; Sulfur Radioisotopes; Tyrosine | 1999 |
Kinetic mechanism of cytochrome P450 reductase from the house fly (Musca domestica).
Topics: Animals; Cysteine; Cytochrome c Group; Electrons; Houseflies; Kinetics; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Recombinant Fusion Proteins; Tyrosine | 1999 |
[The prevalence of the Cys282Tyr mutation in the hemochromatosis gene in Cantabria in patients diagnosed with hereditary hemochromatosis].
Topics: Base Sequence; Cysteine; DNA Primers; Female; Gene Frequency; Genotype; Hemochromatosis; Humans; Male; Molecular Sequence Data; Mutation; Phenotype; Polymerase Chain Reaction; Prevalence; Spain; Tyrosine | 1999 |
High-throughput mass spectrometric discovery of protein post-translational modifications.
Topics: Acetylation; Amides; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Image Processing, Computer-Assisted; Keratins; Lysine; Methionine; Methylation; Molecular Sequence Data; Oxidoreductases; Peptide Elongation Factor Tu; Peptide Mapping; Peroxidases; Peroxiredoxins; Phenylalanine; Protein Processing, Post-Translational; Software; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 1999 |
Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.
Topics: Aging; Amino Acid Sequence; Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cysteine; Endopeptidases; Isoenzymes; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Nitrates; Nitric Oxide; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Sarcoplasmic Reticulum; Sulfhydryl Compounds; Tyrosine | 1999 |
Prevalence of hemochromatosis related HFE gene mutations in patients with acute myeloid leukemia.
Topics: Acute Disease; Codon; Cysteine; Hemochromatosis; Humans; Leukemia, Myeloid; Mutation; Prevalence; Tyrosine | 1999 |
Myeloperoxidase-catalyzed oxidation of tyrosine.
Topics: Animals; Cattle; Cross-Linking Reagents; Cysteine; Free Radicals; Glutathione; Kinetics; Methionine; Molecular Weight; Oxidants; Oxidation-Reduction; Peptides; Peroxidase; Sulfhydryl Reagents; Tyrosine | 1999 |
Contribution of separate tryptophan residues to intrinsic fluorescence of actin. Analysis of 3D structure.
Topics: Actins; Cysteine; Fluorescence; Methionine; Models, Molecular; Phenylalanine; Proline; Protein Structure, Secondary; Solvents; Tryptophan; Tyrosine | 1999 |
Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cattle; COS Cells; Cysteine; Cytoplasm; Disulfides; Leucine; Light; Molecular Sequence Data; Palmitic Acid; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridines; Rhodopsin; Spectrometry, Fluorescence; Sulfhydryl Reagents; Transducin; Tyrosine | 1999 |
Site-directed mutagenesis and molecular modeling identify a crucial amino acid in specifying the heparin affinity of FGF-1.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Cysteic Acid; Cysteine; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Heparin; Humans; Iodine Radioisotopes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Tyrosine | 1999 |
The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells.
Topics: Amino Acid Substitution; Animals; Base Sequence; Cysteine; DNA Polymerase beta; Frameshift Mutation; Humans; Mice; Molecular Sequence Data; Mutagenesis; Phenotype; Rats; Sequence Deletion; Tyrosine | 1999 |
Proteolytic processing of Caenorhabditis elegans SQT-1 cuticle collagen is inhibited in right roller mutants whereas cross-linking is inhibited in left roller mutants.
Topics: Animals; Blotting, Western; Caenorhabditis elegans; Collagen; Cross-Linking Reagents; Cysteine; Helminth Proteins; Mutation; Procollagen; Protein Conformation; Subtilisins; Tyrosine | 1999 |
Importance of F1-ATPase residue alpha-Arg-376 for catalytic transition state stabilization.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Arginine; Binding Sites; Catalysis; Cysteine; Enzyme Stability; Escherichia coli; Fluorine; Glutamine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1999 |
Structure-based design of non-nucleoside reverse transcriptase inhibitors of drug-resistant human immunodeficiency virus.
Topics: Alanine; Anti-HIV Agents; Computer Simulation; Cysteine; Drug Design; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Pyridines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiourea; Tyrosine; Valine | 1999 |
Cys97-->Tyr mutation in the glycoprotein IX gene associated with Bernard-Soulier syndrome.
Topics: Bernard-Soulier Syndrome; Cysteine; Humans; Male; Middle Aged; Mutation; Platelet Glycoprotein GPIb-IX Complex; Sequence Analysis, DNA; Tyrosine | 1999 |
A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1)
Topics: Cell Nucleus; Chromosome Mapping; Cysteine; Cytoplasm; DNA; HeLa Cells; Histone Acetyltransferases; Humans; Male; Middle Aged; Mutation; Nuclear Receptor Coactivator 1; Prostatic Neoplasms; Receptors, Androgen; Response Elements; Transcription Factors; Transfection; Tyrosine; X Chromosome | 1999 |
[Demonstration of HFE polymorphism in German patients with hereditary hemochromatosis].
Topics: Amino Acid Sequence; Asparagine; Chromosomes, Human, Pair 6; Codon; Cysteine; Germany; Hemochromatosis; Heterozygote; Histidine; HLA Antigens; Homozygote; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Tyrosine | 1999 |
No evidence of increased risk of colorectal cancer in individuals heterozygous for the Cys282Tyr haemochromatosis mutation.
Topics: Aged; Chi-Square Distribution; Colorectal Neoplasms; Cysteine; Electrophoresis, Polyacrylamide Gel; Female; Genes, MHC Class I; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Mutation; Polymerase Chain Reaction; Risk Factors; Tyrosine | 1999 |
Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathione; Humans; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Melanosomes; Monophenol Monooxygenase; Neoplasm Proteins; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine | 1999 |
Position-specific codon conservation in hypervariable gene families.
Topics: Amino Acid Sequence; Animals; Codon; Conserved Sequence; Cysteine; Databases, Factual; Evolution, Molecular; Humans; Molecular Sequence Data; Multigene Family; Receptors, Odorant; Tyrosine | 2000 |
Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs.
Topics: Blotting, Western; Carrier Proteins; Catalysis; Cell Line; Cysteine; DNA, Complementary; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Models, Chemical; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Tyrosine | 2000 |
Clinical characteristics of type 2 diabetes in patients with mutations of HFE.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Female; Ferritins; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Insulin Resistance; Iron; Major Histocompatibility Complex; Male; Membrane Proteins; Middle Aged; Point Mutation; Transferrin; Tyrosine | 2000 |
A functional significance for codon third bases.
Topics: Amino Acids; Base Composition; Base Sequence; Binding Sites; Codon; Cysteine; Databases, Factual; Genes; Humans; Membrane Proteins; Mitogens; Nucleotides; Polymorphism, Genetic; Receptors, Cell Surface; Receptors, Growth Factor; Second Messenger Systems; Tyrosine | 2000 |
Non-sequential vasopressin peptides. Stereochemistry and biological activity.
Topics: Amino Acid Sequence; Animals; Arginine; Cysteine; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Magnesium; Magnetic Resonance Spectroscopy; Male; Models, Chemical; Molecular Sequence Data; Peptide Biosynthesis; Peptides; Protein Conformation; Rats; Stereoisomerism; Tyrosine; Vasopressins | 2000 |
The reduction potential of the beta-carotene.+ /beta-carotene couple in an aqueous micro-heterogeneous environment.
Topics: beta Carotene; Cations; Cysteine; Electron Transport; Free Radicals; Hydrogen-Ion Concentration; Micelles; Oxidants; Photosynthetic Reaction Center Complex Proteins; Pulse Radiolysis; Reducing Agents; Solutions; Spectrophotometry, Infrared; Thermodynamics; Tryptophan; Tyrosine; Water | 2000 |
Reaction of human myoglobin and H2O2. Involvement of a thiyl radical produced at cysteine 110.
Topics: Animals; Ascorbic Acid; Cyclic N-Oxides; Cysteine; Dimerization; Disulfides; Electron Spin Resonance Spectroscopy; Free Radicals; Horses; Humans; Hydrogen Peroxide; Mass Spectrometry; Myoglobin; Recombinant Proteins; Spin Labels; Tyrosine | 2000 |
A novel missense mutation (Y89C) in exon 3 of the CFTR (ABCC7) gene in a young male.
Topics: Adult; Amino Acid Substitution; Animals; ATP-Binding Cassette Transporters; Cysteine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; Humans; Male; Mice; Mutation, Missense; Rats; Tyrosine | 2000 |
Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy.
Topics: Administration, Inhalation; Animals; Cysteine; Epithelium; Female; Immunohistochemistry; Lung; Mice; Nitric Oxide; Nitroso Compounds; S-Nitrosothiols; Tyrosine | 2000 |
Towards models of vanadate-dependent haloperoxidases: the hydroxyl side chain.
Topics: Binding Sites; Cysteine; Homoserine; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Structure; Peroxidases; Protein Tyrosine Phosphatases; Serine; Threonine; Tyrosine; Vanadates | 2000 |
A heterozygous novel C253Y mutation in the highly conserved cysteine residues of ROM1 gene is the cause of retinitis pigmentosa in a Spanish family?
Topics: Conserved Sequence; Cysteine; Eye Proteins; Genetic Carrier Screening; Germ-Line Mutation; Humans; Membrane Proteins; Mutation, Missense; Retinitis Pigmentosa; Rod Cell Outer Segment; Spain; Tetraspanins; Tyrosine | 2000 |
Catalytic control and coupling efficiency of the Escherichia coli FoF1 ATP synthase: influence of the Fo sector and epsilon subunit on the catalytic transition state.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Biological Transport; Catalysis; Cysteine; Detergents; Dimethylamines; Enzyme Activation; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Proton-Translocating ATPases; Protons; Tyrosine | 2000 |
Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation.
Topics: Amino Acid Substitution; Animals; Antigens, Polyomavirus Transforming; Brain Neoplasms; Colony-Forming Units Assay; Cysteine; Genes, fos; Genes, p53; Genes, Reporter; Humans; Mutagenesis, Site-Directed; Osteosarcoma; Point Mutation; Promoter Regions, Genetic; Rats; Recombinant Proteins; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyrosine | 2000 |
Prevalence of the C282Y mutation for haemochromatosis on the Island of Majorca.
Topics: Adult; Cysteine; DNA Primers; Female; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Male; Membrane Proteins; Mutation; Polymerase Chain Reaction; Prevalence; Seroepidemiologic Studies; Spain; Tyrosine | 2000 |
NMR structure of oxidized glutaredoxin 3 from Escherichia coli.
Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Cysteine; Disulfides; Escherichia coli; Glutaredoxins; Glutathione; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxidoreductases; Oxygen; Protein Binding; Protein Conformation; Proteins; Reducing Agents; Sequence Alignment; Solvents; Substrate Specificity; Thermodynamics; Tyrosine | 2000 |
Photoreduction of methemoglobin by irradiation in the near-ultraviolet region.
Topics: Anions; Carbon Monoxide; Cyanides; Cysteine; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Fluorides; Hemoglobins; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Methemoglobin; Oxidation-Reduction; Oxygen; Photolysis; Protein Binding; Spectrophotometry, Ultraviolet; Tyrosine; Ultraviolet Rays | 2000 |
Crystal structure of the peptidyl-cysteine decarboxylase EpiD complexed with a pentapeptide substrate.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Carboxy-Lyases; Crystallography, X-Ray; Cysteine; Flavin Mononucleotide; Flavoproteins; Models, Molecular; Molecular Sequence Data; Oxidoreductases; Oxygen; Peptides; Protein Processing, Post-Translational; Protein Structure, Secondary; Recombinant Proteins; Ribosomes; Sequence Homology, Amino Acid; Staphylococcus epidermidis; Tyrosine | 2000 |
Prevalence of mutations causing retinitis pigmentosa and other inherited retinopathies.
Topics: Amino Acid Substitution; Animals; Arginine; Cysteine; Genetic Variation; Glutamine; Homeodomain Proteins; Humans; Intermediate Filament Proteins; Leucine; Membrane Glycoproteins; Mutation; Nerve Tissue Proteins; Optic Atrophies, Hereditary; Peripherins; Prevalence; Proline; Retinal Degeneration; Retinal Diseases; Retinitis Pigmentosa; Rhodopsin; Trans-Activators; Tyrosine | 2001 |
Two novel mutations (Y141H; C214Y) and previously published mutation (R142W) in the RDS-peripherin gene in autosomal dominant macular dystrophies in Spanish families.
Topics: Amino Acid Substitution; Arginine; Cysteine; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Genes, Dominant; Histidine; Humans; Intermediate Filament Proteins; Macular Degeneration; Membrane Glycoproteins; Mutation, Missense; Nerve Tissue Proteins; Peripherins; Polymerase Chain Reaction; Retinal Degeneration; Tryptophan; Tyrosine | 2001 |
Second mutations rescue point mutant of the Na(+)/H(+) exchanger NHE1 showing defective surface expression.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cell Line; Cell Membrane; Cysteine; Mammals; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Sodium; Sodium-Hydrogen Exchangers; Transfection; Tyrosine | 2000 |
A novel Cys212Tyr founder mutation in parkin and allelic heterogeneity of juvenile Parkinsonism in a population from North West Colombia.
Topics: Adolescent; Adult; Age of Onset; Alleles; Colombia; Cysteine; Family Health; Female; Founder Effect; Genetic Heterogeneity; Humans; Ligases; Male; Parkinsonian Disorders; Pedigree; Point Mutation; Tyrosine; Ubiquitin-Protein Ligases | 2001 |
Histochemistry of the cuticle from proventriculus in stingless bee, Melipona quadrifasciata anthidioides (Hymenoptera, Apidae).
Topics: Alcian Blue; Animals; Bees; Carbohydrates; Coloring Agents; Cysteine; Epidermis; Ferricyanides; Histocytochemistry; Microscopy, Electron, Scanning; Periodic Acid-Schiff Reaction; Proteins; Tolonium Chloride; Tyrosine | 2000 |
Haemochromatosis: automated detection of the two point mutations in the HFE gene: Cys282Tyr and His63Asp.
Topics: Aspartic Acid; Cysteine; DNA Mutational Analysis; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Point Mutation; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2000 |
Helix packing in the lactose permease of Escherichia coli: distances between site-directed nitroxides and a lanthanide.
Topics: Binding Sites; Chelating Agents; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Gadolinium; Heterocyclic Compounds; Isoleucine; Membrane Transport Proteins; Mesylates; Metals, Rare Earth; Monoiodotyrosine; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Nitrobenzenes; Protein Structure, Secondary; Serine; Spin Labels; Symporters; Tyrosine | 2001 |
Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions.
Topics: Amino Acid Sequence; Arginine; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Glutathione Transferase; Isoenzymes; Kinetics; Leucine; Ligands; Lipid Metabolism; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phorbol Esters; Phospholipids; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Tyrosine | 2001 |
Reaction of human myoglobin and H2O2. Electron transfer between tyrosine 103 phenoxyl radical and cysteine 110 yields a protein-thiyl radical.
Topics: Amino Acid Substitution; Animals; Cyclic N-Oxides; Cysteine; Dimerization; Disulfides; Electron Spin Resonance Spectroscopy; Free Radicals; Globins; Horses; Humans; Hydrogen Peroxide; Kinetics; Mutagenesis, Site-Directed; Myoglobin; Phenols; Recombinant Proteins; Spin Labels; Tyrosine | 2001 |
A point mutation in the LIM domain of Lhx3 reduces activation of the glycoprotein hormone alpha-subunit promoter.
Topics: Binding Sites; Cell Line; Cysteine; DNA; DNA-Binding Proteins; Genes, Reporter; Genetic Vectors; Glutathione Transferase; Glycoprotein Hormones, alpha Subunit; Homeodomain Proteins; Humans; Immunoblotting; LIM-Homeodomain Proteins; Mutation; Phenotype; Point Mutation; Precipitin Tests; Prolactin; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Transcription Factor Pit-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine; Zinc Fingers | 2001 |
The Y181C mutant of HIV-1 reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors alters the size distribution of RNase H cleavages.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Cysteine; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Hydrolysis; Mutagenesis, Site-Directed; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA, Viral; Tyrosine | 2001 |
Replication of a pre-existing resistant HIV-1 subpopulation in vivo after introduction of a strong selective drug pressure.
Topics: Codon; Cysteine; Drug Resistance, Microbial; Follow-Up Studies; HIV Infections; HIV-1; Humans; Mutation; Nevirapine; Polymerase Chain Reaction; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Tyrosine; Viral Load | 1996 |
The structure of a zeta class glutathione S-transferase from Arabidopsis thaliana: characterisation of a GST with novel active-site architecture and a putative role in tyrosine catabolism.
Topics: Amino Acid Sequence; Arabidopsis; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Dimerization; Glutathione; Glutathione Transferase; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Sequence Alignment; Serine; Tyrosine | 2001 |
Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Aspartic Acid; Brain Infarction; Cardiovascular Diseases; Case-Control Studies; Cysteine; Female; France; Genetic Predisposition to Disease; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Myocardial Infarction; Northern Ireland; Polymorphism, Genetic; Prevalence; Prospective Studies; Tyrosine; Ultrasonography; United Kingdom | 2001 |
Incorporation of caged cysteine and caged tyrosine into a transmembrane segment of the nicotinic ACh receptor.
Topics: Animals; Cell Membrane; Codon, Nonsense; Cysteine; Membrane Potentials; Mice; Molecular Probe Techniques; Molecular Structure; Oocytes; Photolysis; Protein Structure, Tertiary; Receptors, Nicotinic; Suppression, Genetic; Tyrosine; Xenopus laevis | 2001 |
Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation.
Topics: 3T3 Cells; Animals; Blotting, Northern; Blotting, Western; Catalysis; Cell Line; Culture Media, Serum-Free; Cysteine; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; Isoenzymes; Mice; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxidative Stress; Oxygen; Phosphorylation; Precipitin Tests; Protein Binding; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptors, Platelet-Derived Growth Factor; Time Factors; Transfection; Tyrosine | 2001 |
One-electron reduction potentials of dietary carotenoid radical cations in aqueous micellar environments.
Topics: Carotenoids; Cations; Cysteine; Dipeptides; Free Radicals; Hydrogen-Ion Concentration; Micelles; Oxidation-Reduction; Pulse Radiolysis; Spectrophotometry; Tryptophan; Tyrosine; Water | 2001 |
NAD+-dependent DNA ligase encoded by a eukaryotic virus.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Base Sequence; Catalysis; Cysteine; DNA Ligases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; Gene Deletion; Genetic Vectors; Models, Biological; Molecular Sequence Data; Mutation; NAD; Phylogeny; Poxviridae; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Tyrosine; Zinc; Zinc Fingers | 2001 |
Functional roles of the tyrosine within the NP(X)(n)Y motif and the cysteines in the C-terminal juxtamembrane region of the CB2 cannabinoid receptor.
Topics: Adenylyl Cyclases; Amino Acid Motifs; Cannabinoids; Cells, Cultured; Cysteine; Humans; Ligands; Models, Molecular; Mutagenesis; Receptors, Cannabinoid; Receptors, Drug; Tyrosine | 2001 |
Induction of oxidative stress by homocyst(e)ine impairs endothelial function.
Topics: Acetylcholine; Animals; Aorta; Caspases; Cysteine; Elastin; Endothelium, Vascular; Glutathione; Homocysteine; In Vitro Techniques; Metalloendopeptidases; Niacinamide; Nitric Oxide; Nitroprusside; Oxidative Stress; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Tyrosine; Vasodilation | 2001 |
Germline RET 634 mutation positive MEN 2A-related C-cell hyperplasias have genetic features consistent with intraepithelial neoplasia.
Topics: Amino Acid Substitution; Antigens, Nuclear; Autoantigens; Calcitonin; Carcinoma, Medullary; Cysteine; DNA Primers; Drosophila Proteins; Female; Focal Epithelial Hyperplasia; Genes, Retinoblastoma; Germ-Line Mutation; Humans; Ki-67 Antigen; Loss of Heterozygosity; Multiple Endocrine Neoplasia Type 2a; Nerve Tissue Proteins; Neurofibromin 1; Nuclear Proteins; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Diseases; Thyroid Neoplasms; Thyroidectomy; Tyrosine | 2001 |
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C.
Topics: Animals; Brain; Cysteine; Isoenzymes; Male; Neurodegenerative Diseases; Nitrates; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; Penicillamine; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tissue Extracts; Tyrosine | 2001 |
Hemochromatosis gene variants in patients with cardiomyopathy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Cardiomyopathies; Cysteine; Disease Progression; Female; Genotype; Heart Failure; Hemochromatosis; Histidine; Humans; Logistic Models; Male; Middle Aged; Mutation, Missense; Prognosis; Tyrosine | 2001 |
The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis.
Topics: Animals; Anisomycin; Apoptosis; Blotting, Western; Cell Line; Cell Membrane; COS Cells; Cysteine; DNA, Complementary; Drosophila Proteins; Ectoderm; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glycosylation; Humans; Ligands; Mutation; Nerve Growth Factors; Nerve Tissue Proteins; Neuroglia; Neurons; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Signal Transduction; Time Factors; Tyrosine | 2001 |
Association between Cys282Tyr missense mutation and haptoglobin phenotype polymorphism in patients with chronic hepatitis C.
Topics: Adult; Aged; Alleles; Case-Control Studies; Chi-Square Distribution; Cohort Studies; Cysteine; Female; Genetic Predisposition to Disease; Genetic Testing; Haptoglobins; Hepatitis C, Chronic; Humans; Male; Middle Aged; Mutation, Missense; Phenotype; Polymorphism, Genetic; Prevalence; Probability; Reference Values; Risk Assessment; Tyrosine | 2001 |
C282Y and H63D mutations in the HFE gene have no effect on iron overload disorders in Japan.
Topics: Adult; Asian People; Aspartic Acid; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Hepatitis C, Chronic; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Iron Overload; Japan; Liver Diseases; Male; Membrane Proteins; Middle Aged; Point Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity.
Topics: Amino Acid Sequence; Amino Acids; Animals; Baculoviridae; Binding Sites; Blotting, Western; Carbon-Carbon Ligases; Catalysis; Catalytic Domain; Cell Line; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Insecta; Ions; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Phenylalanine; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Prothrombin; Rabbits; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tyrosine; Vitamin K | 2001 |
Actin carbonylation: from a simple marker of protein oxidation to relevant signs of severe functional impairment.
Topics: Actin Cytoskeleton; Actins; Animals; Biomarkers; Carbonic Acid; Cross-Linking Reagents; Cysteine; Fluorometry; Hypochlorous Acid; In Vitro Techniques; Methionine; Muscle, Skeletal; Oxidation-Reduction; Rabbits; Tyrosine | 2001 |
The frequency of C282Y and H63D mutations in Hemochromatosis gene in native Estonians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Aspartic Acid; Cysteine; DNA Mutational Analysis; DNA Primers; Estonia; Female; Gene Frequency; Genotype; Hemochromatosis; Histidine; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Impaired protein folding, dimer formation, and heterotetramer assembly cause intra- and extracellular instability of a Y283C mutant of the A subunit for coagulation factor XIII.
Topics: Amino Acid Substitution; Cysteine; Dimerization; Factor XIII; Humans; Mutation; Protein Folding; Tumor Cells, Cultured; Tyrosine | 2001 |
Structure of bacteriophage P22 portal protein in relation to assembly: investigation by Raman spectroscopy.
Topics: Bacteriophage P22; Capsid; Capsid Proteins; Cysteine; Models, Molecular; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2001 |
The X-ray crystal structure of human gamma S-crystallin C-terminal domain.
Topics: Animals; Base Sequence; Crystallins; Crystallography, X-Ray; Cysteine; DNA Primers; Humans; Hydrogen Bonding; Models, Molecular; Protein Conformation; Sequence Homology, Amino Acid; Tyrosine | 2002 |
Tyrosine residues near the FAD binding site are critical for FAD binding and for the maintenance of the stable and active conformation of rat monoamine oxidase A.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Enzyme Stability; Flavin-Adenine Dinucleotide; Humans; Kinetics; Molecular Sequence Data; Monoamine Oxidase; Point Mutation; Protein Conformation; Rats; Substrate Specificity; Tyrosine; Yeasts | 2002 |
Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Binding Sites; Cell Separation; COS Cells; Cross-Linking Reagents; Cysteine; Dimerization; DNA, Complementary; Epitopes; Flow Cytometry; Glycine; Humans; Interleukin Receptor Common gamma Subunit; Interleukin-15; Interleukin-2; Interleukin-4; Interleukin-7; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Cytokine; Receptors, Interleukin-7; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2002 |
Effect of the intermolecular disulfide bond on the conformation and stability of glial cell line-derived neurotrophic factor.
Topics: Amino Acid Sequence; Cell Line; Circular Dichroism; Cysteine; Disulfides; Glial Cell Line-Derived Neurotrophic Factor; Heparin; Hot Temperature; Hydrogen-Ion Concentration; Mutation; Nerve Growth Factors; Nerve Tissue Proteins; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tyrosine | 2002 |
Peroxyl adduct radicals formed in the iron/oxygen reconstitution reaction of mutant ribonucleotide reductase R2 proteins from Escherichia coli.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Glycine; Iron; Oxygen; Peroxides; Point Mutation; Ribonucleotide Reductases; Tryptophan; Tyrosine | 2002 |
Site-directed rotational resonance solid-state NMR distance measurements probe structure and mechanism in the transmembrane domain of the serine bacterial chemoreceptor.
Topics: Carbon Isotopes; Cysteine; Glycine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Receptors, Amino Acid; Rotation; Serine Endopeptidases; Tyrosine | 2002 |
Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.
Topics: Acetaminophen; Adolescent; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Child; Chromatography, High Pressure Liquid; Cysteine; Endopeptidases; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Predictive Value of Tests; Proteins; Sensitivity and Specificity; Time Factors; Tyrosine | 2002 |
Mechanism in the reaction of cytochrome c oxidase with organic hydroperoxides: an ESR spin-trapping investigation.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Oxidative Stress; Spin Labels; tert-Butylhydroperoxide; Tryptophan; Tyrosine | 2002 |
Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Base Sequence; Cell Line; Circular Dichroism; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutathione Transferase; Insecta; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Point Mutation; Potassium; Proline; Protein Folding; Recombinant Proteins; Sequence Homology, Amino Acid; Spider Venoms; Tyrosine; Ultraviolet Rays | 2002 |
Function assignment to conserved residues in mammalian alkaline phosphatases.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Conserved Sequence; Cysteine; Disulfides; Dose-Response Relationship, Drug; Epitopes; Histidine; Humans; Kinetics; Leucine; Ligands; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Software; Spectrometry, Fluorescence; Time Factors; Tyrosine; Zinc | 2002 |
Identification of the regulatory elements of the human von Willebrand factor for binding to platelet GPIb. Importance of structural integrity of the regions flanked by the CYS1272-CYS1458 disulfide bond.
Topics: Anti-Bacterial Agents; Binding Sites; Biotinylation; Blood Platelets; Cell Line; Crotalid Venoms; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Epitope Mapping; Gene Deletion; Humans; Immunoglobulin G; Models, Molecular; Plasmids; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Ristocetin; Tyrosine; von Willebrand Factor | 2002 |
Pulse radiolysis studies on galactose oxidase.
Topics: Catalysis; Copper; Cysteine; Fusarium; Galactose Oxidase; Isoenzymes; Kinetics; Models, Chemical; Oxidation-Reduction; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tyrosine | 2002 |
Novel missense mutation in the purine nucleoside phosphorylase gene in a Japanese patient with purine nucleoside phosphorylase deficiency.
Topics: Child; Cysteine; DNA Mutational Analysis; Female; Humans; Metabolism, Inborn Errors; Mutation, Missense; Purine-Nucleoside Phosphorylase; Severe Combined Immunodeficiency; Tyrosine | 2002 |
EPR studies on a stable sulfinyl radical observed in the iron-oxygen-reconstituted Y177F/I263C protein R2 double mutant of ribonucleotide reductase from mouse.
Topics: Animals; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Escherichia coli; Ferrous Compounds; Free Radicals; Isoleucine; Mice; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Recombinant Proteins; Ribonucleotide Reductases; Spectrophotometry; Tyrosine | 2002 |
New structural insights from Raman spectroscopy of proteins and their assemblies.
Topics: Arginine; Cations; Crystallography, X-Ray; Cysteine; Hydrogen Bonding; Inovirus; Models, Molecular; Protein Structure, Secondary; Salmonella typhimurium; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Ultraviolet Rays; Water | 2002 |
Single cysteine to tyrosine transition inactivates the growth inhibitory function of Piedmontese myostatin.
Topics: Amino Acid Substitution; Animals; Cattle; Cell Division; Cell Line; Cysteine; Growth Inhibitors; Muscles; Mutation; Myostatin; Reference Values; RNA Stability; RNA, Messenger; Transforming Growth Factor beta; Tyrosine | 2002 |
Prevalence of hemochromatosis-related symptoms among individuals with mutations in the HFE gene.
Topics: Adult; Aged; Aspartic Acid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Ferritins; Genetic Predisposition to Disease; Genetic Testing; Genotype; Hemochromatosis; Hispanic or Latino; Histidine; Homozygote; Humans; Male; Middle Aged; Mutation; Prevalence; Surveys and Questionnaires; Transferrin; Tyrosine; United States; White People | 2002 |
Nitration/S-nitrosation of proteins by peroxynitrite-treatment and subsequent modification by glutathione S-transferase and glutathione peroxidase.
Topics: Animals; Blotting, Western; Cattle; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hemoglobins; Histones; Horses; In Vitro Techniques; Mice; Nitrosation; Oxidative Stress; Peroxynitrous Acid; S-Nitrosothiols; Tyrosine | 2002 |
Increased frequency of cysteine, tyrosine, and phenylalanine residues since the last universal ancestor.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Databases, Protein; Evolution, Molecular; Genetic Code; Models, Genetic; Phenylalanine; Proteome; Time Factors; Tyrosine | 2002 |
The role of cysteine residues in the oxidation of ferritin.
Topics: Centrifugation, Density Gradient; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Ferritins; Humans; Mass Spectrometry; Oxidation-Reduction; Peptide Fragments; Protein Binding; Spectrometry, Fluorescence; Spin Labels; Trypsin; Tyrosine | 2002 |
Prophylactic thyroidectomy in MEN 2A syndrome: experience in a single center.
Topics: Adolescent; Adult; Calcitonin; Child; Child, Preschool; Cysteine; Drosophila Proteins; Female; Humans; Infant; Male; Multiple Endocrine Neoplasia Type 2a; Mutation; Neoplasm Recurrence, Local; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Function Tests; Thyroid Neoplasms; Thyroidectomy; Tyrosine | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
Disulfide-bond formation in the transthyretin mutant Y114C prevents amyloid fibril formation in vivo and in vitro.
Topics: Adult; Amino Acid Substitution; Amyloid; Amyloid Neuropathies, Familial; Antibodies, Monoclonal; Crystallography, X-Ray; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Epitopes; Female; Humans; Middle Aged; Mutagenesis, Site-Directed; Oxidation-Reduction; Prealbumin; Protein Conformation; Recombinant Proteins; Tyrosine | 2002 |
EPR detection of glutathiyl and hemoglobin-cysteinyl radicals during the interaction of peroxynitrite with human erythrocytes.
Topics: Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Humans; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Spin Labels; Tyrosine | 2002 |
The beta G156C substitution in the F1-ATPase from the thermophilic Bacillus PS3 affects catalytic site cooperativity by destabilizing the closed conformation of the catalytic site.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Bacillus; Binding Sites; Catalysis; Catalytic Domain; Cysteine; Dimethylamines; Enzyme Stability; Glutamic Acid; Glycine; Hydrolysis; Magnesium; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Sodium Azide; Tryptophan; Tyrosine; Valine | 2002 |
Activation of microsomal glutathione s-transferase by peroxynitrite.
Topics: Animals; Cysteine; Enzyme Activation; Glutathione Transferase; Hydrogen Peroxide; Imidazoles; Male; Microsomes, Liver; Nitrates; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tetranitromethane; Tyrosine | 2003 |
Importance of Cys, Gln, and Tyr from the transmembrane domain of human alpha 3/4 fucosyltransferase III for its localization and sorting in the Golgi of baby hamster kidney cells.
Topics: Amino Acid Motifs; Animals; Biotinylation; Blotting, Western; Cell Membrane; Cells, Cultured; Cricetinae; Cysteine; Dimerization; Disulfides; Fluorescent Antibody Technique, Indirect; Fucosyltransferases; Glutamine; Golgi Apparatus; Humans; Kidney; Microscopy, Electron; Microscopy, Fluorescence; Plasmids; Protein Structure, Tertiary; Protein Transport; Subcellular Fractions; Tyrosine | 2003 |
Peroxynitrite-induced inhibition and nitration of cardiac myofibrillar creatine kinase.
Topics: Blotting, Western; Creatine Kinase; Cysteine; Dose-Response Relationship, Drug; Kinetics; Myocardium; Myofibrils; Nitrates; Peroxynitrous Acid; Reactive Nitrogen Species; Tyrosine | 2002 |
Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling.
Topics: Amino Acid Motifs; Antibodies, Monoclonal; Binding Sites; CD3 Complex; CD4 Antigens; CD8 Antigens; Cell Membrane; Cross-Linking Reagents; Cysteine; Gene Targeting; Humans; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Microdomains; Muromonab-CD3; Mutagenesis, Site-Directed; Palmitic Acid; Phosphorylation; Plasmids; Sequence Deletion; Signal Transduction; T-Lymphocytes; Tyrosine | 2003 |
Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
Topics: Arachidonic Acid; Blood Proteins; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Aromatic residues at the extracellular ends of transmembrane domains 5 and 6 promote ligand activation of the G protein-coupled alpha-factor receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Extracellular Space; GTP-Binding Proteins; Ligands; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Novobiocin; Phenotype; Phenylalanine; Protein Structure, Tertiary; Receptors, Cell Surface; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Transcription Factors; Tyrosine | 2003 |
Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Cysteine; Feeding Behavior; Female; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Humans; Iron Compounds; Male; Meat; Membrane Proteins; Middle Aged; Mutation; North Carolina; Risk Assessment; Risk Factors; Tyrosine | 2003 |
Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors.
Topics: Carbon-Carbon Double Bond Isomerases; Catalytic Domain; Crystallography; Cysteine; Epoxy Compounds; Escherichia coli; Glutamic Acid; Hemiterpenes; Kinetics; Organophosphorus Compounds; Protein Structure, Secondary; Tyrosine | 2003 |
Coupling of contact sensitizers to thiol groups is a key event for the activation of monocytes and monocyte-derived dendritic cells.
Topics: Acetates; Anti-Infective Agents; Antioxidants; Cysteine; Dendritic Cells; Ethylmaleimide; Humans; Interleukin-1; Lysine; Maleimides; MAP Kinase Signaling System; Monocytes; Phosphorylation; Picryl Chloride; Succinimides; Sulfhydryl Compounds; Sulfhydryl Reagents; Thiazoles; Tyrosine | 2003 |
Isolation, purification, and physicochemical characterization of a D-galactose-binding lectin from seeds of Erythrina speciosa.
Topics: Animals; Calcium; Carbohydrates; Chromatography; Chromatography, Agarose; Circular Dichroism; Concanavalin A; Cysteine; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Fabaceae; Galactose; Hemagglutination; Horses; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Lectins; Manganese; Mass Spectrometry; Mice; Protein Structure, Tertiary; Rabbits; Seeds; Sheep; Spectrometry, Fluorescence; Temperature; Tryptophan; Tyrosine; Ultraviolet Rays | 2003 |
Aromatic stacking in the sugar binding site of the lactose permease.
Topics: Alkylation; Amino Acids, Aromatic; Binding Sites; Biological Transport, Active; Cysteine; Escherichia coli Proteins; Ethylmaleimide; Kinetics; Lactose; Membrane Transport Proteins; Monosaccharide Transport Proteins; Nitrophenylgalactosides; Phenylalanine; Substrate Specificity; Symporters; Thiogalactosides; Tryptophan; Tyrosine | 2003 |
Sequence and properties of HMW subunit 1Bx20 from pasta wheat (Triticum durum) which is associated with poor end use properties.
Topics: Amino Acid Sequence; Circular Dichroism; Crosses, Genetic; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutens; Molecular Sequence Data; Molecular Weight; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectroscopy, Fourier Transform Infrared; Triticum; Tyrosine | 2003 |
Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide synthase.
Topics: Circular Dichroism; Cysteine; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Humans; Iron-Sulfur Proteins; Ligands; Mutagenesis, Site-Directed; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Phenylalanine; Protein Structure, Tertiary; Solvents; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 2003 |
Novel mutations in the gene encoding secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related protein-1 (SLURP-1) and description of five ancestral haplotypes in patients with Mal de Meleda.
Topics: Aged; Antigens, Ly; Base Sequence; Conserved Sequence; Cysteine; Female; Founder Effect; Haplotypes; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Keratoderma, Palmoplantar; Male; Molecular Sequence Data; Mutation; Pedigree; Protein Sorting Signals; Tyrosine; Urokinase-Type Plasminogen Activator | 2003 |
Substrate specificity of mutants of the hydroxynitrile lyase from Manihot esculenta.
Topics: Alanine; Aldehyde-Lyases; Chromatography, Gas; Cysteine; Leucine; Manihot; Mutation; Nitriles; Tyrosine | 2003 |
The soluble ectodomain of RetC634Y inhibits both the wild-type and the constitutively active Ret.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Cells, Cultured; Cysteine; Dimerization; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glycosylation; Humans; Ligands; Multiple Endocrine Neoplasia Type 2a; Nerve Growth Factors; PC12 Cells; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Solubility; Tyrosine | 2003 |
Actin tyrosine dephosphorylation by the Src homology 1-containing protein tyrosine phosphatase is essential for actin depolymerization after membrane IgM cross-linking.
Topics: Actins; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line; Chickens; Cross-Linking Reagents; Cysteine; Humans; Intracellular Signaling Peptides and Proteins; Membrane Microdomains; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Polymers; Protein Binding; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Serine; src Homology Domains; Substrate Specificity; Transfection; Tyrosine | 2003 |
Immunochemical detection of hemoglobin-derived radicals formed by reaction with hydrogen peroxide: involvement of a protein-tyrosyl radical.
Topics: Ascorbic Acid; Blotting, Western; Cysteine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Humans; Hydrogen Peroxide; Immunochemistry; Models, Chemical; Time Factors; Tyrosine | 2003 |
A novel mutation A1270G of the EDA1 gene causing Tyr343Cys substitution in ectodysplasin-A in a family with anhidrotic ectodermal dysplasia.
Topics: Adenine; Amino Acid Substitution; Base Sequence; Cysteine; Ectodermal Dysplasia; Ectodysplasins; Exons; Female; Guanine; Humans; Infant; Male; Membrane Proteins; Mutation, Missense; Pedigree; Tyrosine | 2003 |
Altered kinetic properties of tyrosine-183 to cysteine mutation in glutamine synthetase of anabaena variabilis strain SA1 is responsible for excretion of ammonium ion produced by nitrogenase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anabaena; Base Sequence; Cysteine; Glutamate-Ammonia Ligase; Kinetics; Magnesium; Manganese; Molecular Sequence Data; Nitrogenase; Point Mutation; Quaternary Ammonium Compounds; Sequence Alignment; Tyrosine | 2003 |
Natural disulfide bond-disrupted mutants of AVR4 of the tomato pathogen Cladosporium fulvum are sensitive to proteolysis, circumvent Cf-4-mediated resistance, but retain their chitin binding ability.
Topics: Alanine; Amino Acids; Blood Proteins; Carrier Proteins; Chitin; Chromatography, High Pressure Liquid; Cladosporium; Cysteine; Disulfides; Fungal Proteins; Genotype; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Necrosis; Peptides; Phenotype; Polysaccharides; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Solanum lycopersicum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Transcription, Genetic; Tyrosine | 2003 |
Population screening for hemochromatosis: a study in 5370 Spanish blood donors.
Topics: Adult; Aspartic Acid; Blood Donors; Cysteine; Female; Ferritins; Gene Frequency; Genetic Testing; Genotype; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Sex Characteristics; Spain; Transferrin; Tyrosine | 2003 |
Protein and gene analyses of dysferlinopathy in a large group of Japanese muscular dystrophy patients.
Topics: Age of Onset; Alanine; Blotting, Western; Calpain; Cysteine; Cytoskeletal Proteins; DNA Mutational Analysis; Dysferlin; Dystroglycans; Dystrophin; Glycine; Humans; Immunohistochemistry; Japan; Membrane Glycoproteins; Membrane Proteins; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophies; Mutation; Neuromuscular Diseases; Sarcoglycans; Sequence Analysis, Protein; Tyrosine | 2003 |
Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13.
Topics: ADAM Proteins; ADAMTS13 Protein; Amino Acid Motifs; Animals; Baculoviridae; Biotinylation; Cell Line; Cell Membrane; Cells, Cultured; COS Cells; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Epitopes; Extracellular Matrix; Gene Deletion; Genetic Vectors; Humans; Insecta; Metalloendopeptidases; Microscopy, Fluorescence; Plasmids; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Transfection; Tyrosine; von Willebrand Factor | 2003 |
Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite.
Topics: Alanine; Amino Acids; Animals; Arginine; Binding Sites; Cysteine; Eukaryotic Initiation Factor-4G; Glutathione Transferase; Glycine; Models, Genetic; Models, Molecular; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; Reticulocytes; Rhinovirus; Rosaniline Dyes; Time Factors; Tyrosine | 2003 |
Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; COS Cells; Cysteine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Genes, Reporter; Humans; Isoleucine; Kinetics; Ligands; Mesylates; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Sequence Homology, Amino Acid; Transfection; Tyrosine; Water | 2003 |
Detection of cysteine S-nitrosylation and tyrosine 3-nitration in kidney proteins.
Topics: Animals; Biotin; Blotting, Western; Chromatography, High Pressure Liquid; Cysteine; Electrochemistry; In Vitro Techniques; Kidney; Mice; Nitric Oxide; Proteins; Rats; Tyrosine | 2003 |
Heterozygosity for the Cys282Tyr mutation in the HFE gene and the risk of colorectal cancer (Netherlands).
Topics: Aged; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Cysteine; Female; Genotype; Hemochromatosis Protein; Heterozygote; Histocompatibility Antigens Class I; Humans; Membrane Proteins; Middle Aged; Mutation; Netherlands; Odds Ratio; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Smoking; Tyrosine | 2003 |
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Topics: Amino Acid Sequence; Antigens, Surface; Biotinylation; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Lymphocyte Antigen 96; Lysine; Membrane Glycoproteins; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Sequence Data; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors; Transfection; Tyrosine | 2003 |
Phosphorylation by cAMP-dependent protein kinase modulates the structural coupling between the transmembrane and cytosolic domains of phospholamban.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Calcium; Calcium-Binding Proteins; Cyclic AMP-Dependent Protein Kinases; Cysteine; Cytosol; Escherichia coli Proteins; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Intracellular Membranes; Maleimides; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Sarcoplasmic Reticulum; Sulfhydryl Reagents; Tyrosine | 2003 |
The synthesis of beta-sulfo-L-Alanyl-L-tyrosine and L-tyrosyl-L-cysteic acid and their dibromotyrosyl analogues.
Topics: Cysteic Acid; Cysteine; Dipeptides; Organic Chemicals; Tyrosine | 1953 |
[Dinitrophenylene-bis-amino acids from cysteine, also from glycine, lysine and tyrosine].
Topics: Amino Acids; Cysteine; Glycine; Lysine; Nitrobenzenes; Tyrosine | 1958 |
[The formation of a reaction product of cysteine and N-(chloroacetyl)-tyrosine and its hydrolysis by proteolytic enzymes].
Topics: Biochemical Phenomena; Cysteine; Endopeptidases; Hydrolases; Hydrolysis; Peptide Hydrolases; Tyrosine | 1958 |
The in vitro inhibition of catalase activity by several metabolites of amino acid.
Topics: Ascorbic Acid; Catalase; Cysteine; Glutathione; Humans; In Vitro Techniques; Liver; Tyrosine; Uric Acid; Vitamin K; Xanthines | 1962 |
Cysteine stimulation of glucose oxidation in thyroid tissue.
Topics: Amino Acids; Animals; Cattle; Cysteamine; Cysteine; Glucose; Oxidation-Reduction; Thyroid Gland; Thyrotropin; Tyrosine | 1963 |
Effect of various compounds on the rate of thiamine hydrolysis.
Topics: Cysteine; Cystine; Hydrolysis; Ketones; Oximes; Thiamine; Tyrosine | 1963 |
[HISTOCHEMICAL STUDIES ON NORMAL AND PATHOLOGICAL STRUCTURE OF GLIAL FIBERS].
Topics: Amino Acids; Carbohydrates; Central Nervous System Diseases; Cysteine; Cystine; Histocytochemistry; Humans; Neuroglia; Proteins; Tyrosine; Vasopressins | 1963 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
A HISTOCHEMICAL COMPARISON OF THE INCLUSION BODIES OF CANINE DISTEMPER AND INFECTIOUS CANINE HEPATITIS.
Topics: Animals; Arginine; Carbohydrate Metabolism; Coloring Agents; Cysteine; Cystine; Distemper; DNA; DNA, Viral; Dog Diseases; Dogs; Hepatitis, Animal; Hepatitis, Infectious Canine; Histocytochemistry; Inclusion Bodies; Lipid Metabolism; Minerals; RNA; RNA, Viral; Staining and Labeling; Tryptophan; Tyrosine; Viruses | 1963 |
A MANOMETRIC DETERMINATION OF SULFHYDRYL GROUPS AND ITS APPLICATION TO PROTEINS IN NATIVE AND DENATURED STATES.
Topics: Arginine; Cysteine; Erythrocytes; Glutathione; Hemoglobins; Histidine; Insulin; Manometry; Ovalbumin; Proline; Proteins; Pyridines; Research; Serum Albumin; Sulfhydryl Compounds; Tyrosine | 1963 |
[SPECIFICITY OF ACTIVATION ENZYMES WITH RESPECT TO RIBONUCLEIC ACIDS ESTERIFIED BY AMINO ACIDS].
Topics: Alanine; Amino Acids; Animals; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Ligases; Methionine; Nucleoproteins; Poultry; Proteins; Research; RNA; RNA, Bacterial; Serine; Sulfur Isotopes; Tyrosine | 1963 |
ASPECTS OF CHEMORECEPTION IN CRUSTACEA.
Topics: Aminobutyrates; Animals; Aspartic Acid; Crustacea; Cysteine; Electrophysiology; Glutamates; Glutathione; Glycine; Glycogen; Histamine; Indoles; Leucine; Methionine; Muscles; Pharmacology; Research; Sensory Receptor Cells; Serine; Tyrosine; Urea | 1963 |
[ON THE LOCALIZATION OF SOME AMINO ACIDS IN THE MEMBRANOUS SEMICIRCULAR CANAL. HISTOCHEMICAL STUDY].
Topics: Amino Acids; Arginine; Cysteine; Histocytochemistry; Rabbits; Research; Semicircular Canals; Tryptophan; Tyrosine | 1963 |
[CONCERNING THE HISTOCHEMISTRY AND ULTRASTRUCTURE OF THE VITELLINE GRANULES IN THE GALLUS DOMESTICUS EGG].
Topics: Animals; Arginine; Chickens; Cysteine; Cystine; Egg Yolk; Glycoproteins; Histidine; Histocytochemistry; Phospholipids; Polysaccharides; Research; Tryptophan; Tyrosine | 1963 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
A SIMPLE PREPARATION METHOD FOR DIPHOSPHOMIDAZOLE.
Topics: Alanine; Amides; Calcium Phosphates; Chlorides; Chromatography; Cysteine; Cystine; Glycine; Histidine; Imidazoles; Ion Exchange Resins; Methionine; Phosphates; Phosphorus; Research; Serine; Tryptophan; Tyrosine | 1964 |
RELATIONSHIP OF RAT LIVER CATHEPSINS TO AUTOLYTIC DEGRADATION OF PROTEINS OF THE LIVER CELL NUCLEUS DURING ISOLATION. INTRACELLULAR DISTRIBUTION AND PROPERTIES OF THE CATHEPSINS.
Topics: Arginine; Cathepsins; Cell Nucleus; Cysteine; Cytoplasm; Liver; Microsomes; Mitochondria; Peptide Hydrolases; Pharmacology; Proteins; Rats; Research; Tyrosine | 1964 |
FUNCTION-SPECIFIC CHANGES IN THE METABOLISM OF AGOUTI PIGMENT CELLS.
Topics: Animals; Chromatophores; Cysteine; Dasyproctidae; Dihydroxyphenylalanine; Glutathione; Hair; Leucine; Melanins; Metabolism; Mice; Research; Serine; Sulfhydryl Compounds; Tyrosine | 1964 |
HISTOCHEMICAL ALKYLATION: A STUDY OF METHYL IODIDE AND ITS EFFECT ON TISSUES.
Topics: Alkylating Agents; Alkylation; Amines; Arginine; Cysteine; Glycols; Histocytochemistry; Hydrocarbons, Iodinated; Iodides; Metabolism; Phosphates; Sulfates; Toxicology; Tryptophan; Tyrosine | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
THE INFLUENCE OF ETHIONINE, METHIONINE, CHOLINE, AND RELATED COMPOUNDS ON LIVER GLYCOGEN DEPOSITION IN ADRENALECTOMIZED RATS: RELATION TO THE MODE OF ACTION OF GLUCOCORTICOIDS.
Topics: Adrenalectomy; Choline; Cysteine; Ethionine; Glucocorticoids; Glucose; Homocysteine; Hydrocortisone; Liver; Liver Glycogen; Methionine; Pharmacology; Research; Serine; Tyrosine | 1964 |
THE REACTION OF BETA-LACTOGLOBULIN SULFENYL IODIDE WITH SEVERAL ANTITHYROID AGENTS.
Topics: Antithyroid Agents; Chemical Phenomena; Chemistry; Cysteine; Globulins; Iodides; Lactoglobulins; Mercaptoethanol; Physiology; Research; Sulfides; Sulfur; Thiouracil; Thiourea; Thyroid Gland; Tyrosine | 1964 |
VASOPRESSIN BIOSYNTHESIS. 3. IN VITRO STUDIES.
Topics: Animals; Arginine Vasopressin; Cysteine; Guinea Pigs; Hypothalamo-Hypophyseal System; In Vitro Techniques; Metabolism; Pharmacology; Puromycin; Research; Tyrosine; Vasopressins | 1964 |
EVIDENCE FOR A PRECURSOR IN VASOPRESSIN BIOSYNTHESIS.
Topics: Arginine Vasopressin; Cerebral Ventricles; Cysteine; Dogs; Hypothalamus; Metabolism; Pharmacology; Puromycin; Research; Tyrosine; Vasopressins | 1964 |
HISTOCHEMICAL DEMONSTRATION OF SOME AMINO ACIDS IN THE TOOTH GERM OF THE RAT'S UPPER INCISORS.
Topics: Amelogenesis; Amino Acids; Cysteine; Cystine; Dental Enamel Proteins; Histocytochemistry; Incisor; Indoles; Mouth Mucosa; Phenols; Rats; Research; Sulfhydryl Compounds; Tooth Germ; Tryptophan; Tyrosine | 1964 |
THE SEPARATION AND PARTIAL PURIFICATION OF AMINOACYL-RNA SYNTHETASES FROM ESCHERICHIA COLI.
Topics: Amino Acids; Chromatography; Cysteine; Diphosphates; Escherichia coli; Isoleucine; Leucine; Ligases; Methionine; Phosphorus Isotopes; Research; RNA; RNA-Dependent RNA Polymerase; RNA, Bacterial; Tryptophan; Tyrosine; Valine | 1964 |
A NEW REAGENT FOR NITROGUANIDINATION OF PROTEINS.
Topics: Amino Acids; Animals; Cattle; Chemistry Techniques, Analytical; Cysteine; Electrophoresis; Guanidines; Histidine; Indicators and Reagents; Indoles; Molecular Weight; Phenols; Proteins; Pyrazoles; Research; Serum Albumin; Serum Albumin, Bovine; Tryptophan; Tyrosine; Ultracentrifugation | 1964 |
HYDROGEN ION EQUILIBRIA OF HUMAN CARBONIC ANHYDRASES B AND C.
Topics: Amino Acids; Carbonic Anhydrase I; Carbonic Anhydrases; Cysteine; Humans; Hydrogen-Ion Concentration; Protons; Spectrophotometry; Tyrosine | 1965 |
TRIFLUROACETYLATED AMINO ACID ESTERS: THE STABILITY OF THE DERIVATIVES OF CYSTEINE, HYDROXYPROLINE, SERINE, THREONINE AND TYROSINE.
Topics: Acetates; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Esters; Hydroxyproline; Research; Serine; Threonine; Tyrosine | 1965 |
RELATION OF BIOCHEMICAL MUTATIONS TO ACTINOMYCIN SYNTHESIS IN STREPTOMYCES ANTIBIOTICUS.
Topics: Adenine; Amino Acids; Arginine; Culture Media; Cysteine; Dactinomycin; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Mutation; Phenylalanine; Research; Streptomyces; Streptomyces antibioticus; Threonine; Tyrosine; Ultraviolet Rays; Uracil; Valine | 1965 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
Receptor activator of NF-kappa B ligand stimulates recruitment of SHP-1 to the complex containing TNFR-associated factor 6 that regulates osteoclastogenesis.
Topics: Animals; Carrier Proteins; Cell Differentiation; Cell Line; Cysteine; Genetic Vectors; Glycoproteins; Intracellular Signaling Peptides and Proteins; Ligands; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NF-kappa B; Osteoclasts; Osteoprotegerin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Protein Subunits; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Retroviridae; Serine; src Homology Domains; TNF Receptor-Associated Factor 6; Transduction, Genetic; Tyrosine; Up-Regulation | 2003 |
Oxidative inactivation of purified plasma membrane Ca2+-ATPase by hydrogen peroxide and protection by calmodulin.
Topics: Animals; Calcium-Transporting ATPases; Calmodulin; Cation Transport Proteins; Cattle; Cysteine; Dithiothreitol; Enzyme Activation; Erythrocyte Membrane; Histidine; Humans; Hydrogen Peroxide; Leucine; Oxidation-Reduction; Plasma Membrane Calcium-Transporting ATPases; Protein Conformation; Serine; Spectrometry, Fluorescence; Tyrosine; Valine | 2003 |
A new pitfall in detecting biological end products of nitric oxide-nitration, nitros(yl)ation and nitrite/nitrate artefacts during freezing.
Topics: Animals; Aorta; Buffers; Cryopreservation; Cysteine; Freezing; Humans; Hydrogen-Ion Concentration; Nitrates; Nitric Oxide; Nitrites; Nitrophenols; Nitroso Compounds; Phosphates; Potassium Compounds; Rats; S-Nitrosothiols; Serum Albumin, Bovine; Tyrosine | 2003 |
Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity.
Topics: Adenoviridae; alpha-Synuclein; Animals; Apoptosis; beta-Synuclein; Blotting, Western; Cell Line; Cell Survival; Cloning, Molecular; Cysteine; Detergents; Dimerization; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neurons; Nitrogen; Octoxynol; Oxidative Stress; Oxygen; Phenylalanine; Plasmids; Protein Binding; Proteins; Rats; Recombinant Proteins; Synucleins; Time Factors; Transfection; Tyrosine | 2004 |
Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Chromans; Cysteine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucose; Lipid Peroxides; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Retina; Selenium; Tyrosine | 2003 |
Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers.
Topics: Acetylcysteine; Antigen-Presenting Cells; Antioxidants; Cells, Cultured; Cysteine; Dermatitis, Contact; Glutathione; Humans; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Picryl Chloride; Sulfhydryl Compounds; Tyrosine | 2003 |
Strategies and methods of cross-linking of RNA polymerase active center.
Topics: Binding Sites; Biochemistry; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; Cyanogen Bromide; Cysteine; DNA-Directed RNA Polymerases; Hydroxylamines; Models, Chemical; Models, Genetic; Protein Transport; Time Factors; Tryptophan; Tyrosine | 2003 |
Selective prion protein binding to synaptic components is modulated by oxidative and nitrosative changes induced by copper(II) and peroxynitrite in cholinergic synaptosomes, unveiling a role for calcineurin B and thioredoxin.
Topics: 14-3-3 Proteins; Animals; Blotting, Western; Calcineurin; Carbocyanines; Choline O-Acetyltransferase; Copper Sulfate; Cyclophilin A; Cysteine; Dose-Response Relationship, Drug; Epitopes; Humans; In Vitro Techniques; Membrane Glycoproteins; Membrane Proteins; Mercaptoethanol; Nerve Tissue Proteins; Neurons; Nitrosation; Oxidation-Reduction; Peroxynitrous Acid; Prions; Protein Binding; Pyruvic Acid; Qa-SNARE Proteins; R-SNARE Proteins; Recombinant Proteins; S-Nitrosothiols; Sheep; Synapsins; Synaptic Vesicles; Synaptosomes; Tacrolimus Binding Proteins; Thioredoxins; Time Factors; Torpedo; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
Albumin oxidation to diverse radicals by the peroxidase activity of Cu,Zn-superoxide dismutase in the presence of bicarbonate or nitrite: diffusible radicals produce cysteinyl and solvent-exposed and -unexposed tyrosyl radicals.
Topics: Antioxidants; Bicarbonates; Cysteine; Diffusion; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Kinetics; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Serum Albumin, Bovine; Solvents; Spin Trapping; Sulfhydryl Compounds; Superoxide Dismutase; Tyrosine | 2004 |
Protein radical formation during lactoperoxidase-mediated oxidation of the suicide substrate glutathione: immunochemical detection of a lactoperoxidase radical-derived 5,5-dimethyl-1-pyrroline N-oxide nitrone adduct.
Topics: Amino Acids; Ascorbic Acid; Azides; Blotting, Western; Catalase; Cyclic N-Oxides; Cysteine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Free Radicals; Glutathione; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; Immunochemistry; Iodides; Lactoperoxidase; Models, Chemical; Nitrites; Nitrogen Oxides; Oxygen; Oxygen Consumption; Phenol; Spin Labels; Thiocyanates; Time Factors; Tyrosine | 2004 |
The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Cohort Studies; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Iron Overload; Membrane Proteins; Middle Aged; Mutation; Phenotype; Tyrosine | 2004 |
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine | 2004 |
Mapping of catalytically important residues in the rat L-histidine decarboxylase enzyme using bioinformatic and site-directed mutagenesis approaches.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Catalysis; Computational Biology; Cysteine; Histidine Decarboxylase; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Sequence Homology, Amino Acid; Swine; Trypsin; Tyrosine | 2004 |
A different amyloid formation mechanism: de novo oculoleptomeningeal amyloid deposits after liver transplantation.
Topics: Adult; Amyloid; Amyloid Neuropathies, Familial; Central Nervous System Diseases; Cysteine; Eye; Eye Diseases; Female; Humans; Liver Transplantation; Magnetic Resonance Imaging; Male; Meninges; Methionine; Middle Aged; Mutation; Pia Mater; Postoperative Period; Prealbumin; Tyrosine; Valine | 2004 |
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
Topics: Adenine; Adenoma; Adenomatous Polyposis Coli; Adult; Aged; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; Cysteine; DNA Glycosylases; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Deletion; Gene Frequency; Germ-Line Mutation; Glycine; Guanine; Humans; Italy; Male; Middle Aged; Tyrosine | 2004 |
Functional characterization of nitric oxide and YC-1 activation of soluble guanylyl cyclase: structural implication for the YC-1 binding site?
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; COS Cells; Cyclic GMP; Cysteine; Cytosol; DNA Mutational Analysis; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitric Oxide; Phenotype; Protein Subunits; Pyrazoles; Pyridines; Rats; Solubility; Tyrosine | 2004 |
Juvenile Parkinson disease and the C212Y mutation of parkin.
Topics: Colombia; Cysteine; Humans; Mutation; Parkinsonian Disorders; Spain; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
Rescue of protein splicing activity from a Magnetospirillum magnetotacticum intein-like element.
Topics: Alanine; Alternative Splicing; Catalysis; Cysteine; Magnetospirillum; Models, Genetic; Mutation; Phenylalanine; Polymorphism, Genetic; Protein Splicing; Protein Structure, Tertiary; RNA Splicing; Serine; Tyrosine | 2004 |
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress.
Topics: Amides; Amino Acids; Bromates; Cell Survival; Computer Simulation; Cysteine; Disulfides; Humans; Kinetics; Methionine; Models, Chemical; Oxidative Stress; Phagocytes; Serum Albumin; Tyrosine | 2004 |
MERTK arginine-844-cysteine in a patient with severe rod-cone dystrophy: loss of mutant protein function in transfected cells.
Topics: Adolescent; Arginine; Blotting, Western; c-Mer Tyrosine Kinase; Cysteine; Female; Gene Expression Regulation; Genetic Variation; Humans; Kidney; Mutation, Missense; Phosphorylation; Photoreceptor Cells, Vertebrate; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tyrosine | 2004 |
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
Topics: Aldehydes; Animals; Biomarkers; Body Weight; Carboxylic Acids; Cysteine; Dinitrophenols; Energy Intake; Free Radical Scavengers; Gentamicins; Hydroxyl Radical; Immunohistochemistry; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine; Urine | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Crosslinking of and coupling to viral capsid proteins by tyrosine oxidation.
Topics: Capsid Proteins; Comovirus; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Mutation; Nickel; Oxidation-Reduction; Peptides; Photochemistry; Phthalic Acids; Protein Structure, Quaternary; Ruthenium; Spectrum Analysis; Temperature; Tyrosine; Virion | 2004 |
Duplex polymerase chain reaction-restriction fragment length polymorphism assay for rapid detection of HFE mutations-C282Y occurs with a low frequency in Tehran's population.
Topics: Cysteine; Gene Frequency; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Iran; Membrane Proteins; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Tyrosine | 2004 |
Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes.
Topics: Aspartic Acid; Confidence Intervals; Cysteine; Denmark; Female; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Mutation; Tyrosine | 2004 |
Roles of cysteine 161 and tyrosine 154 in the lecithin-retinol acyltransferase mechanism.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cysteine; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Sequence Alignment; Tyrosine; Viral Proteins | 2004 |
HFE gene and hemochromatosis.
Topics: Aspartic Acid; Cysteine; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Membrane Proteins; Mutation; Mutation, Missense; Tyrosine | 2004 |
Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzheimer Disease: from risk factors to disease modulators.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoproteins E; Case-Control Studies; Chi-Square Distribution; Cholesterol 24-Hydroxylase; Cysteine; Female; Follow-Up Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Introns; Male; Mental Status Schedule; Odds Ratio; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Steroid Hydroxylases; Time Factors; Tyrosine | 2004 |
Cysteine-scanning mutagenesis and thiol modification of the Rickettsia prowazekii ATP/ADP translocase: evidence that transmembrane regions I and II, but not III, are structural components of the aqueous translocation channel.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Ethyl Methanesulfonate; Ion Channel Gating; Isoleucine; Mesylates; Mitochondrial ADP, ATP Translocases; Molecular Sequence Data; Mutagenesis; Mutation; Phenylalanine; Rickettsia prowazekii; Sequence Homology, Amino Acid; Sulfhydryl Compounds; Translocation, Genetic; Tyrosine | 2004 |
Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase.
Topics: Alleles; Binding Sites; Catalysis; Cysteine; Escherichia coli; Galactose; Humans; Models, Biological; Models, Molecular; Mutation; Pichia; Plasmids; Saccharomyces cerevisiae; Serine; Substrate Specificity; Tyrosine; UDPglucose 4-Epimerase; Uridine Diphosphate N-Acetylgalactosamine; Uridine Diphosphate N-Acetylglucosamine | 2004 |
Oxygen tension and inhaled nitric oxide modulate pulmonary levels of S-nitrosocysteine and 3-nitrotyrosine in rats.
Topics: Administration, Inhalation; Animals; Cysteine; Humans; Infant; Isoenzymes; Lung; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Rats; S-Nitrosothiols; Tyrosine | 2004 |
Interaction of the disintegrin and cysteine-rich domains of ADAM12 with integrin alpha7beta1.
Topics: ADAM Proteins; ADAM12 Protein; Alternative Splicing; Animals; Binding Sites; Cell Adhesion; Cell Line; Cell Membrane; Cysteine; Disintegrins; Epithelial Cells; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Laminin; Ligands; Manganese; Membrane Proteins; Metalloendopeptidases; Muscle, Skeletal; Myoblasts; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Transfection; Tyrosine | 2004 |
Model of glycoprotein hormone receptor ligand binding and signaling.
Topics: Amino Acid Sequence; Animals; Binding Sites; Callithrix; COS Cells; Cysteine; Dimerization; Disulfides; Dose-Response Relationship, Drug; Epitopes; Humans; Leucine; Ligands; Lysine; Models, Biological; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptors, Cell Surface; Receptors, FSH; Salmon; Signal Transduction; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.
Topics: Amino Acids; Aspartic Acid; Base Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; DNA; Electrophoretic Mobility Shift Assay; Glutathione; Indicators and Reagents; Monocrotaline; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Tyrosine | 2004 |
The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo.
Topics: Amyloid beta-Protein Precursor; Animals; Binding Sites; Caenorhabditis elegans Proteins; Copper; Cysteine; Gliosis; Humans; Ion Transport; Membrane Proteins; Memory; Neurons; Neurotoxicity Syndromes; Peptides; Protein Structure, Tertiary; Proteins; Rats; Tyrosine | 2004 |
Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1.
Topics: Adenine; Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Viral; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Humans; Insecta; Kinetics; Leukotriene C4; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tyrosine | 2004 |
Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis.
Topics: Amino Acid Sequence; Animals; Binding Sites; COS Cells; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Kinetics; Ligands; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Tyrosine | 2004 |
Antibodies directed against nitrosylated neoepitopes in sera of patients with human African trypanosomiasis.
Topics: Antibody Affinity; Antibody Specificity; Autoantibodies; Autoantigens; Carrier Proteins; Cysteine; Enzyme-Linked Immunosorbent Assay; Glutaral; Humans; Nitric Oxide; Nitroso Compounds; Severity of Illness Index; Trypanosomiasis, African; Tyrosine | 2004 |
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay.
Topics: Age Factors; Animals; Blotting, Western; Body Mass Index; Body Weight; Brain-Derived Neurotrophic Factor; Child; COS Cells; Cysteine; Developmental Disabilities; DNA Mutational Analysis; Eating; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Male; MAP Kinase Signaling System; Memory Disorders; Mutation, Missense; Obesity; PC12 Cells; Phosphorylation; Rats; Receptor, trkB; Transfection; Tyrosine | 2004 |
[Hereditary hemochromatosis: molecular diagnosis and effect of treatment].
Topics: Adult; Cysteine; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Male; Membrane Proteins; Mutation; Phlebotomy; Polymerase Chain Reaction; Tyrosine | 2004 |
Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk.
Topics: Adenomatous Polyposis Coli; Aspartic Acid; Base Pair Mismatch; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Cysteine; DNA Glycosylases; DNA Mutational Analysis; DNA, Neoplasm; Gene Frequency; Genetic Predisposition to Disease; Germ-Line Mutation; Glycine; Humans; Loss of Heterozygosity; Ontario; Phenotype; Risk Factors; Tyrosine | 2004 |
Tempol diverts peroxynitrite/carbon dioxide reactivity toward albumin and cells from protein-tyrosine nitration to protein-cysteine nitrosation.
Topics: Albumins; Animals; Antioxidants; Catalysis; Cyclic N-Oxides; Cysteine; Electrochemistry; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Immunoblotting; Immunohistochemistry; Inflammation; Macrophages; Mice; Models, Biological; Models, Chemical; Nitric Oxide; Nitrites; Nitrogen; Oxygen; Peroxynitrous Acid; Serum Albumin, Bovine; Spin Labels; Time Factors; Tyrosine | 2005 |
Mechanism of hydrogen peroxide-induced Cu,Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping: the role of copper- and carbonate radical anion-mediated oxidations.
Topics: Animals; Anions; Binding Sites; Blotting, Western; Carbon; Catalase; Cattle; Copper; Cysteine; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radicals; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Models, Chemical; Oxidants; Oxidation-Reduction; Oxygen; Pentetic Acid; Spin Trapping; Superoxide Dismutase; Superoxides; Time Factors; Tyrosine | 2005 |
Structure of an excitatory insect-specific toxin with an analgesic effect on mammals from the scorpion Buthus martensii Karsch.
Topics: Amino Acid Sequence; Analgesics; Animals; Crystallography, X-Ray; Cysteine; Disulfides; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Scorpion Venoms; Scorpions; Sequence Homology, Amino Acid; Software; Toxins, Biological; Tryptophan; Tyrosine | 2005 |
Peroxynitrite-mediated oxidation of the C85S/C152E mutant of dihydrofolate reductase from Escherichia coli: functional and structural effects.
Topics: Blotting, Western; Calorimetry, Differential Scanning; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Immunoblotting; Mutation; Oxidative Stress; Oxygen; Peroxynitrous Acid; Reactive Oxygen Species; Spectrometry, Fluorescence; Temperature; Tetrahydrofolate Dehydrogenase; Thermodynamics; Time Factors; Tryptophan; Tyrosine | 2005 |
Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.
Topics: Alanine; Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Genes, Suppressor; Genetic Testing; Mating Factor; Molecular Sequence Data; Mutagenesis; Peptides; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2005 |
Human Ran cysteine 112 oxidation by pervanadate regulates its binding to keratins.
Topics: Actins; Cell Line, Tumor; Cell Movement; Cell Survival; Cell-Free System; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Immunoprecipitation; Keratins; Mass Spectrometry; Models, Biological; Mutation; Oxygen; Phosphorylation; Proteasome Inhibitors; Protein Binding; Proteomics; ran GTP-Binding Protein; Tyrosine; Vanadates | 2005 |
CXC chemokine ligand 12-induced focal adhesion kinase activation and segregation into membrane domains is modulated by regulator of G protein signaling 1 in pro-B cells.
Topics: B-Lymphocyte Subsets; Cell Adhesion; Cell Differentiation; Cell Migration Inhibition; Chemokine CXCL12; Chemokines, CXC; Cysteine; Down-Regulation; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Protein alpha Subunits, Gi-Go; Hematopoietic Stem Cells; Humans; MAP Kinase Signaling System; Membrane Microdomains; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; RGS Proteins; src-Family Kinases; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2005 |
Oxidation and tyrosine phosphorylation: synergistic or antagonistic cues in protein tyrosine phosphatase.
Topics: Cysteine; Enzyme Activation; Humans; Models, Biological; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Reactive Oxygen Species; Tyrosine | 2005 |
Nitric oxide-nitric oxide synthase regulates key maturational events during chondrocyte terminal differentiation.
Topics: Alkaline Phosphatase; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chick Embryo; Chondrocytes; Collagen Type X; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cysteine; Gene Expression; Growth Plate; Guanylate Cyclase; Immunohistochemistry; Isoenzymes; Luciferases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Promoter Regions, Genetic; Recombinant Fusion Proteins; S-Nitrosoglutathione; S-Nitrosothiols; Sternum; Transfection; Tretinoin; Tyrosine | 2005 |
Catalytic and direct oxidation of cysteine by octacyanomolybdate(V).
Topics: Catalysis; Copper; Cysteine; Cystine; Hydrogen-Ion Concentration; Kinetics; Molybdenum; Organometallic Compounds; Oxidation-Reduction; Tyrosine | 2005 |
Theoretical and experimental investigations on the reactions of positively charged phenyl radicals with aromatic amino acids.
Topics: Amino Acids, Aromatic; Benzene Derivatives; Cysteine; Free Radicals; Models, Molecular; Phenylalanine; Pyridinium Compounds; Thermodynamics; Tryptophan; Tyrosine | 2005 |
Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study.
Topics: Aging; Carcinoma, Hepatocellular; Case-Control Studies; Cross-Sectional Studies; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Liver Neoplasms; Male; Membrane Proteins; Middle Aged; Mutation; Penetrance; Tyrosine | 2005 |
Impact of HFE genetic testing on clinical presentation of hereditary hemochromatosis: new epidemiological data.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Cohort Studies; Cysteine; Female; France; Genetic Testing; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Middle Aged; Molecular Diagnostic Techniques; Molecular Epidemiology; Sex Ratio; Tyrosine | 2005 |
An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; ATP-Binding Cassette Transporters; Bacterial Proteins; Base Sequence; Binding Sites; Campylobacter jejuni; Carrier Proteins; Crystallography, X-Ray; Cysteine; Cytoplasm; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Tyrosine | 2005 |
Mutations in the hemochromatosis gene (HFE) and multiple sclerosis.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Case-Control Studies; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Middle Aged; Multiple Sclerosis; Mutation; Severity of Illness Index; Tyrosine | 2005 |
Slow solvation dynamics at the active site of an enzyme: implications for catalysis.
Topics: Amino Acyl-tRNA Synthetases; Binding Sites; Catalysis; Circular Dichroism; Cysteine; Glutamine; Hydrogen Sulfide; Kinetics; Models, Molecular; Mutation; Protein Structure, Tertiary; RNA, Transfer; RNA, Transfer, Gln; Solvents; Spectrometry, Fluorescence; Substrate Specificity; Tyrosine | 2005 |
SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; CD47 Antigen; Cell Membrane; Cell Movement; Chlorocebus aethiops; COS Cells; Cysteine; Cytoplasm; Dimerization; Disulfides; Epithelial Cells; HL-60 Cells; Humans; Immunoblotting; Immunoprecipitation; Inflammation; Leukocytes; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, Cell Surface; Receptors, Fc; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Subcellular Fractions; Time Factors; Tyrosine | 2005 |
Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different.
Topics: Animals; Arginine; Cysteine; Databases, Protein; Humans; Magnetic Resonance Spectroscopy; Models, Statistical; Peptides; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Secondary; Proteins; Proteomics; Solvents; Tyrosine | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione.
Topics: Aconitate Hydratase; Amino Acid Sequence; Amino Acids; Animals; Citric Acid; Cysteine; Enzyme Activation; Glutathione; Mass Spectrometry; Molecular Sequence Data; Myocardium; Peroxynitrous Acid; Swine; Tyrosine | 2005 |
Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.
Topics: Amino Acid Sequence; Antigens, CD; Antirheumatic Agents; Base Sequence; Binding Sites; Blotting, Western; Calcium; Cell Line; Cell Membrane; Cell Separation; Chloroquine; Cross-Linking Reagents; Cysteine; Cytokines; Dendritic Cells; Dimerization; DNA; Dose-Response Relationship, Drug; Endosomes; Enzyme Inhibitors; Flow Cytometry; Genes, Dominant; Genes, Reporter; Glycosylation; Humans; Hydrogen-Ion Concentration; Leucine; Leukocytes, Mononuclear; Ligands; Luciferases; Lysosomes; Macrolides; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NF-kappa B; Phagosomes; Protein Binding; Protein Structure, Tertiary; Receptors, IgG; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Toll-Like Receptor 3; Transfection; Tyrosine; U937 Cells | 2005 |
Transthyretin-related familial amyloid polyneuropathy: evaluation of CSF enhancement on serial T1-weighted and fluid-attenuated inversion recovery images following intravenous contrast administration.
Topics: Adult; Amyloid Neuropathies, Familial; Arachnoid; Brain; Contrast Media; Cysteine; Ear, Inner; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Pia Mater; Prealbumin; Tyrosine; Vitreous Body | 2005 |
Pulmonary and systemic nitric oxide metabolites in a baboon model of neonatal chronic lung disease.
Topics: Administration, Inhalation; Animals; Animals, Newborn; Chronic Disease; Cysteine; Disease Models, Animal; Female; Fetus; Free Radical Scavengers; Lung; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; Papio; Pregnancy; S-Nitrosothiols; Tyrosine | 2005 |
Intramolecular electron transfer between tyrosyl radical and cysteine residue inhibits tyrosine nitration and induces thiyl radical formation in model peptides treated with myeloperoxidase, H2O2, and NO2-: EPR SPIN trapping studies.
Topics: Cyclic N-Oxides; Cysteine; Dimerization; Disulfides; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Hydrogen Peroxide; Mass Spectrometry; Nitrites; Oxidation-Reduction; Peptides; Peroxidase; Spin Labels; Tyrosine | 2005 |
Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blood Proteins; Blotting, Western; Catalysis; Catalytic Domain; Cell Line; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; Cloning, Molecular; COS Cells; Cysteine; Diacylglycerol Kinase; Diglycerides; DNA, Complementary; Dose-Response Relationship, Drug; Gene Deletion; Humans; Hydrogen Peroxide; Immunoblotting; Immunoprecipitation; Lipids; Male; Models, Genetic; Molecular Sequence Data; Oxidative Stress; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Plasmids; Protein Isoforms; Protein Structure, Tertiary; RNA, Messenger; Signal Transduction; Swine; Testis; Tissue Distribution; Tyrosine; Zinc Fingers | 2005 |
Atypical MRI findings in Canavan disease: a patient with a mild course.
Topics: Aspartic Acid; Bacterial Proteins; Canavan Disease; Child, Preschool; Chromosomes, Human, Pair 7; Cysteine; Female; Globus Pallidus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mutation; Serine Endopeptidases; Tyrosine | 2005 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine | 2006 |
Hemochromatosis gene HFE Cys282Tyr mutation analysis in a cohort of Northeast German hospitalized patients supports assumption of a North to South allele frequency gradient throughout Germany.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Biomarkers; Cohort Studies; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Germany; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histocompatibility Antigens Class I; Homozygote; Hospitalization; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Tyrosine | 2005 |
Identification of constitutive phosphorylation sites on the Epstein-Barr virus ZEBRA protein.
Topics: Binding Sites; Biochemistry; Cell Line, Tumor; Cell Movement; Cysteine; DNA-Binding Proteins; Escherichia coli; Genetic Vectors; Herpesvirus 4, Human; Humans; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Methionine; Mutagenesis; Peptides; Phosphorylation; Protein Structure, Tertiary; Serine; Threonine; Trans-Activators; Transfection; Trypsin; Tyrosine; Viral Proteins | 2006 |
Unfolding pathways of human serum albumin: evidence for sequential unfolding and folding of its three domains.
Topics: Circular Dichroism; Cysteine; Fluorescence; Fluorescent Dyes; Humans; Kinetics; Maleimides; ortho-Aminobenzoates; Protein Folding; Protein Structure, Tertiary; Serum Albumin; Tryptophan; Tyrosine | 2005 |
The C282Y mutation may have been positively selected as it mitigates the infertility of celiac disease.
Topics: Cation Transport Proteins; Celiac Disease; Cysteine; Hemochromatosis; Humans; Infertility; Iron-Binding Proteins; Mutation; Tyrosine | 2006 |
Raft localisation of FcgammaRIIa and efficient signaling are dependent on palmitoylation of cysteine 208.
Topics: Animals; Antigens, CD; B-Lymphocytes; Calcium Signaling; Cell Line, Tumor; Cysteine; Humans; Membrane Microdomains; Mice; Mutation; Octoxynol; Palmitates; Phosphorylation; Protein Processing, Post-Translational; Receptors, IgG; Tyrosine | 2006 |
Cloning and expression pattern of the Xenopus erythropoietin receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Northern; Cloning, Molecular; Codon, Initiator; Cysteine; Databases, Factual; Embryo, Nonmammalian; Exons; Expressed Sequence Tags; Gene Expression Regulation, Developmental; In Situ Hybridization; Introns; Molecular Sequence Data; Protein Structure, Tertiary; Receptors, Erythropoietin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Tyrosine; Xenopus | 2006 |
A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Amino Acid Substitution; Child, Preschool; Coenzymes; Cysteine; Female; Fibroblasts; Humans; Infant; Male; Mitochondrial Encephalomyopathies; Molecular Sequence Data; Mutation; Mutation, Missense; Tyrosine; Ubiquinone | 2006 |
In vivo rates of erythrocyte glutathione synthesis in adults with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Creatinine; Cysteine; Eating; Erythrocytes; Female; Glutathione; Glutathione Disulfide; Glycine; Humans; Hydrogen Peroxide; Isoprostanes; Male; Statistics, Nonparametric; Tyrosine | 2006 |
15N CIDNP investigations of the peroxynitric acid nitration of L-tyrosine and of related compounds.
Topics: Ascorbic Acid; Cysteine; Glutathione; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Nitrates; Nitrogen; Nitrogen Isotopes; Phenols; Solvents; Temperature; Tyrosine | 2006 |
Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen.
Topics: Amino Acid Sequence; Aminoacyltransferases; Conserved Sequence; Cysteine; Eukaryotic Cells; Evolution, Molecular; Half-Life; Humans; Malaria; Models, Biological; Phylogeny; Prokaryotic Cells; Tyrosine; Vibrio vulnificus | 2006 |
Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Catalysis; Cysteine; Dose-Response Relationship, Drug; Enzyme Stability; Magnesium; Molsidomine; Myosin Subfragments; Oxidation-Reduction; Peroxynitrous Acid; Protein Folding; Rabbits; Skeletal Muscle Myosins; Temperature; Time Factors; Tyrosine | 2006 |
Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Topics: Abnormalities, Drug-Induced; Amino Acid Sequence; Animals; Base Sequence; Calcification, Physiologic; Calcium-Binding Proteins; Cell Adhesion Molecules; Chondrogenesis; Cysteine; Extracellular Matrix Proteins; Female; Glycoproteins; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Osteogenesis; Point Mutation; Signal Transduction; Skull; Spine; Tyrosine | 2006 |
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
Topics: Adult; Aged; Aspartic Acid; Cysteine; Fatty Liver; Female; Genetic Predisposition to Disease; Glucose Intolerance; Hemochromatosis; Hepatitis; Heterozygote; Histidine; Homozygote; Humans; Iron Overload; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prospective Studies; Risk Factors; Tyrosine | 2006 |
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.
Topics: Amino Acid Sequence; Bacterial Proteins; Cysteine; Fusobacterium nucleatum; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurotransmitter Agents; Phylogeny; Plasma Membrane Neurotransmitter Transport Proteins; Protein Structure, Tertiary; Sequence Alignment; Sodium; Symporters; Tyrosine | 2006 |
Cell signaling. H2O2, a necessary evil for cell signaling.
Topics: Cell Membrane; Cysteine; Cytosol; Humans; Hydrogen Peroxide; NADP; Organelles; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Receptors, Cell Surface; Signal Transduction; Tyrosine | 2006 |
A model for the pharmacological treatment of crouzon syndrome.
Topics: Animals; Cranial Sutures; Craniofacial Dysostosis; Cysteine; Disease Models, Animal; Mice; Mice, Mutant Strains; Mutation; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Tissue Culture Techniques; Tomography, X-Ray Computed; Tyrosine | 2006 |
Protection of GroEL by its methionine residues against oxidation by hydrogen peroxide.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chaperonin 60; Circular Dichroism; Cysteine; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hydrolysis; Methionine; Molecular Chaperones; Oxidants; Oxidation-Reduction; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Thiosulfate Sulfurtransferase; Tyrosine | 2006 |
A single mutation at Tyr143 of human S-adenosylhomocysteine hydrolase renders the enzyme thermosensitive and affects the oxidation state of bound cofactor nicotinamide-adenine dinucleotide.
Topics: Adenosylhomocysteinase; Amino Acid Substitution; Catalysis; Cysteine; Dithiothreitol; Enzyme Stability; Escherichia coli; Hot Temperature; Humans; Hydrogen Bonding; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; Oxidation-Reduction; Protein Folding; Protein Structure, Quaternary; Recombinant Proteins; Reducing Agents; Structure-Activity Relationship; Tyrosine | 2006 |
Resonance Raman characterization of archaeal and bacterial Rieske protein variants with modified hydrogen bond network around the [2Fe-2S] center.
Topics: Amino Acid Sequence; Archaeal Proteins; Bacterial Proteins; Cysteine; Electron Transport Complex III; Hydrogen Bonding; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; Rhodobacter sphaeroides; Spectrum Analysis, Raman; Sulfolobus; Tyrosine | 2006 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
Aminoacrylate intermediates in the reaction of Citrobacter freundii tyrosine phenol-lyase.
Topics: Acrylates; Bacterial Proteins; Catalysis; Citrobacter freundii; Cysteine; Pyridines; Pyridones; Tyrosine; Tyrosine Phenol-Lyase | 2006 |
Optimization of the Y831C mutation detection in human DNA polymerase gamma by allelic discrimination assay.
Topics: Cysteine; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Gene Frequency; Genetic Techniques; Humans; Mitochondrial Diseases; Parkinson Disease; Peripheral Nervous System Diseases; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Tyrosine | 2006 |
Replacement surgery with unnatural amino acids in the lock-and-key joint of glutathione transferase subunits.
Topics: Alkylation; Amino Acid Substitution; Butanes; Catalysis; Catalytic Domain; Cysteine; Glutathione S-Transferase pi; Humans; Hydrocarbons, Iodinated; Mass Spectrometry; Mutagenesis, Site-Directed; Protein Engineering; Protein Structure, Secondary; Tyrosine | 2006 |
Spontaneous bilateral carotid artery dissection and hereditary haemochromatosis: what relationship?
Topics: Carotid Artery, Internal, Dissection; Cysteine; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Iron; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Membrane Proteins; Middle Aged; Mutation; Tyrosine | 2006 |
Crystal structures of E. coli CcmG and its mutants reveal key roles of the N-terminal beta-sheet and the fingerprint region.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Protein Disulfide Reductase (Glutathione); Protein Folding; Sequence Alignment; Structure-Activity Relationship; Tyrosine | 2006 |
Characterization of the amino acids from Neisseria meningitidis MsrA involved in the chemical catalysis of the methionine sulfoxide reduction step.
Topics: Cysteine; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Methionine; Methionine Sulfoxide Reductases; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neisseria meningitidis; Oxidative Stress; Oxidoreductases; Sulfhydryl Compounds; Sulfoxides; Tyrosine | 2006 |
An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Coenzymes; Consensus Sequence; Conserved Sequence; Crystallography, X-Ray; Cysteine; Cysteine Dioxygenase; Humans; Kinetics; Mass Spectrometry; Molecular Sequence Data; Mutagenesis; Recombinant Proteins; Sequence Alignment; Sequence Homology; Tyrosine | 2007 |
Mutation screening of the peropsin gene, a retinal pigment epithelium specific rhodopsin homolog, in patients with retinitis pigmentosa and allied diseases.
Topics: Cysteine; DNA Mutational Analysis; Heterozygote; Humans; Mutation, Missense; Retinal Degeneration; Retinitis Pigmentosa; Rhodopsin; Tyrosine | 2006 |
Mechanism of allosteric regulation of transglutaminase 2 by GTP.
Topics: Allosteric Regulation; Animals; Arginine; Binding Sites; Cysteine; Disulfides; GTP-Binding Proteins; Guanosine Triphosphate; Hydrogen Bonding; Models, Molecular; Mutation; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Protein Structure, Tertiary; Rats; Transglutaminases; Tyrosine; Water | 2006 |
Modulation of the electrochemical behavior of tyrosyl radicals by the electrode surface.
Topics: Cysteine; Electrochemistry; Electrodes; Free Radicals; Gold Colloid; Oxidation-Reduction; Surface Properties; Tyrosine | 2007 |
A novel Cys1638Tyr NC1 domain substitution in alpha5(IV) collagen causes Alport syndrome with late onset renal failure without hearing loss or eye abnormalities.
Topics: Adult; Aged; Biopsy; Collagen Type IV; Cysteine; Eye Abnormalities; Female; Genetic Linkage; Glomerular Basement Membrane; Hearing Loss; Humans; Kidney; Male; Middle Aged; Mutation; Nephritis, Hereditary; New Zealand; Pedigree; Renal Insufficiency; Tyrosine | 2007 |
FOXL2 mutations in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome.
Topics: Asian People; Blepharophimosis; Blepharoptosis; Cysteine; Cytosine; Eye Abnormalities; Eyelids; Forkhead Box Protein L2; Forkhead Transcription Factors; Guanine; Heterozygote; Histidine; Humans; Mutation; Mutation, Missense; Polymorphism, Single-Stranded Conformational; Serine; Syndrome; Thymine; Tyrosine | 2007 |
A novel mutation in the SPG3A gene (atlastin) in hereditary spastic paraplegia.
Topics: Adult; Cysteine; DNA Mutational Analysis; Family Health; Female; Genetic Linkage; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Japan; Membrane Proteins; Polymorphism, Genetic; Spastic Paraplegia, Hereditary; Tyrosine | 2007 |
Proteomic analysis of alternative protein tyrosine phosphorylation in 1,2-dichlorovinyl-cysteine-induced cytotoxicity in primary cultured rat renal proximal tubular cells.
Topics: Actin-Related Protein 2; Animals; Apoptosis; Cell Communication; Cells, Cultured; Cysteine; Kidney Tubules, Proximal; Male; Phosphorylation; Protein-Tyrosine Kinases; Proteomics; Rats; Rats, Wistar; Tyrosine | 2007 |
Electronic structure of the PYP chromophore in its native protein environment.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Glutamic Acid; Models, Molecular; Phenylalanine; Photoreceptors, Microbial; Threonine; Tyrosine; Valine | 2007 |
Capillary electrophoresis tandem mass spectrometry of bromine-containing charged derivatives of peptides.
Topics: Bromine; Cysteine; Electrophoresis, Capillary; Indicators and Reagents; Isotope Labeling; Isotopes; Molecular Weight; Peptide Fragments; Peptides; Sequence Analysis; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Tyrosine | 2007 |
A novel GLRA1 mutation in a recessive hyperekplexia pedigree.
Topics: Child; Child, Preschool; Cysteine; DNA Mutational Analysis; Female; Humans; Movement Disorders; Mutation; Pedigree; Receptors, Glycine; Reflex, Startle; Tyrosine | 2007 |
Another mutation in cysteine 131 in protein kinase C gamma as a cause of spinocerebellar ataxia type 14.
Topics: Adenine; Amino Acid Substitution; Cysteine; Guanine; Humans; Magnetic Resonance Imaging; Male; Mutation, Missense; Protein Kinase C; Spinocerebellar Ataxias; Tyrosine | 2007 |
Total anti-oxidant capacity of cell culture media.
Topics: Antioxidants; Benzothiazoles; Chlorides; Colorimetry; Culture Media; Cysteine; Ferric Compounds; Oxidation-Reduction; Phenolsulfonphthalein; Spectrophotometry; Sulfonic Acids; Thiazoles; Tryptophan; Tyrosine | 2007 |
Mutational analysis of active site residues essential for sensing of organic hydroperoxides by Bacillus subtilis OhrR.
Topics: Bacillus subtilis; Bacterial Proteins; Binding Sites; Cysteine; DNA Mutational Analysis; Hydrogen Peroxide; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Repressor Proteins; Structure-Activity Relationship; Transcription Factors; Tyrosine | 2007 |
HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis.
Topics: Adult; Amino Acid Substitution; Cysteine; Fatty Liver; Female; Hemochromatosis Protein; Heterozygote; Histocompatibility Antigens Class I; Humans; Iron; Liver Cirrhosis; Male; Membrane Proteins; Middle Aged; Mutation; Prevalence; Tyrosine; White People | 2007 |
Renoprotective and antihypertensive effects of S-allylcysteine in 5/6 nephrectomized rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Blood Urea Nitrogen; Creatinine; Cysteine; Cytoprotection; Garlic; Hypertension; Kidney; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Nephrectomy; Nitric Oxide Synthase Type II; Plant Extracts; Poly Adenosine Diphosphate Ribose; Proteinuria; Rats; Rats, Wistar; Superoxide Dismutase; Systole; Tyrosine | 2007 |
Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark.
Topics: Adaptation, Ocular; Animals; Aspartic Acid; Calcium; Cyclic GMP; Cysteine; Dark Adaptation; Disease Models, Animal; Electroretinography; Gene Expression Regulation; Glycine; Guanylate Cyclase-Activating Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Physical Stimulation; Retina; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Rhodopsin; Tyrosine | 2007 |
S731 in the transactivation domain modulates STAT5b activity.
Topics: Breast Neoplasms; Cell Line, Tumor; Cysteine; Gene Expression Regulation; Humans; Protein Structure, Tertiary; STAT5 Transcription Factor; Transcriptional Activation; Tyrosine | 2007 |
Photoaddition of fluphenazine to nucleophiles in peptides and proteins. Possible cause of immune side effects.
Topics: Agranulocytosis; Amino Acids; Antipsychotic Agents; Carboxylic Acids; Cysteine; Fluphenazine; Hydrogen-Ion Concentration; Lysine; Peptides; Photolysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine; Ultraviolet Rays | 2007 |
Novel mutation in the PANK2 gene leads to pantothenate kinase-associated neurodegeneration in a Pakistani family.
Topics: Adolescent; Amino Acid Substitution; Basal Ganglia; Child; Cysteine; DNA Mutational Analysis; Genes, Recessive; Homozygote; Humans; Iron; Male; Mutation; Nerve Degeneration; Pakistan; Phosphotransferases (Alcohol Group Acceptor); Tyrosine | 2007 |
The HLA-A1-B8 haplotype hitchhiking with the hemochromatosis mutation: does it affect the phenotype?
Topics: Adult; Aged; Cysteine; Female; Ferritins; Haplotypes; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA-A1 Antigen; HLA-A3 Antigen; HLA-B8 Antigen; Humans; Iron Deficiencies; Male; Membrane Proteins; Middle Aged; Mutation; Pedigree; Phenotype; Sweden; Tyrosine | 2007 |
Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Humans; Myoglobin; Oxyhemoglobins; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spin Trapping; Tyrosine | 2007 |
Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Cysteine; Fluoresceins; Gene Library; Genetic Code; Genetic Variation; Horseradish Peroxidase; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Saccharomyces cerevisiae; Stereoisomerism; Tyrosine | 2007 |
Novel mutations in exon 6 of the GFAP gene affect a highly conserved if motif in the rod domain 2B and are associated with early onset infantile Alexander disease.
Topics: Age of Onset; Alanine; Alexander Disease; Cysteine; DNA Mutational Analysis; Exons; Female; Frontal Lobe; Glial Fibrillary Acidic Protein; Humans; Infant; Magnetic Resonance Imaging; Male; Mutation; Protein Structure, Tertiary; Tyrosine; Valine | 2007 |
Nitric oxide bioavailability and not production is first altered during the onset of insulin resistance in sucrose-fed rats.
Topics: Animals; Aorta; Biomarkers; Cyclic GMP; Cysteine; Diet; Diet Therapy; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation, Enzymologic; Insulin Resistance; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Sucrose; Sweetening Agents; Tyrosine | 2007 |
Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cysteine; HeLa Cells; Humans; Mass Spectrometry; Mice; Molecular Sequence Data; Neoplasms; NIH 3T3 Cells; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Reactive Oxygen Species; Tyrosine | 2008 |
Effect of ortho-SR groups on O-H bond strength and H-atom donating ability of phenols: a possible role for the Tyr-Cys link in galactose oxidase active site?
Topics: Binding Sites; Catalysis; Cysteine; Galactose Oxidase; Hydrogen Bonding; Phenols; Protein Binding; Tyrosine | 2008 |
H2O2/nitrite-induced post-translational modifications of human hemoglobin determined by mass spectrometry: redox regulation of tyrosine nitration and 3-nitrotyrosine reduction by antioxidants.
Topics: Amino Acid Sequence; Antioxidants; Ascorbic Acid; Cysteine; Hemin; Hemoglobins; Humans; Hydrogen Peroxide; Methionine; Molecular Sequence Data; Nitrates; Nitrites; Oxidation-Reduction; Peroxidase; Protein Processing, Post-Translational; Reactive Nitrogen Species; Spectrometry, Mass, Electrospray Ionization; Trypsin; Tyrosine; Vitamin B 12 | 2008 |
The cysteine-cluster motif of c-Src: its role for the heavy metal-mediated activation of kinase.
Topics: Animals; Cells, Cultured; Chlorocebus aethiops; COS Cells; CSK Tyrosine-Protein Kinase; Cysteine; Enzyme Activation; Mercuric Chloride; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-yes; src Homology Domains; src-Family Kinases; Transfection; Tyrosine | 2008 |
Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1.
Topics: Catalysis; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutathione; Glutathione S-Transferase pi; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Trinitrobenzenes; Tyrosine | 2008 |
Effect of liver transplantation on transthyretin Tyr114Cys-related cerebral amyloid angiopathy.
Topics: Adult; Cerebral Amyloid Angiopathy; Cysteine; Female; Humans; Liver Transplantation; Male; Middle Aged; Prealbumin; Retrospective Studies; Tyrosine | 2008 |
Tauroursodeoxycholic acid: relieving the pathogenesis of HFE C282Y hereditary hemochromatosis.
Topics: Antioxidants; Cysteine; Endoplasmic Reticulum; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Membrane Proteins; Mutation; Reactive Oxygen Species; Taurochenodeoxycholic Acid; Tyrosine | 2008 |
The Y606C RET mutation causes a receptor gain of function.
Topics: Amino Acid Substitution; Animals; Base Sequence; Carcinoma, Medullary; Cysteine; Female; Germ-Line Mutation; Humans; Mice; Middle Aged; Multiple Endocrine Neoplasia Type 2a; NIH 3T3 Cells; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Tyrosine | 2008 |
Glutathionylation of the iron superoxide dismutase from the psychrophilic eubacterium Pseudoalteromonas haloplanktis.
Topics: Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Eubacterium; Glutathione; Mass Spectrometry; Mutant Proteins; Peroxynitrous Acid; Pseudoalteromonas; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 2008 |
Genetic deficiency of complement factor H in a patient with age-related macular degeneration and membranoproliferative glomerulonephritis.
Topics: Amino Acid Substitution; Animals; Base Sequence; Blotting, Western; Chlorocebus aethiops; Complement Factor H; COS Cells; Cysteine; Eye; Genetic Predisposition to Disease; Glomerulonephritis, Membranoproliferative; Humans; Kidney; Macular Degeneration; Mass Spectrometry; Middle Aged; Molecular Sequence Data; Mutation; Recombinant Proteins; Tyrosine | 2008 |
Chemosorption of radiometals of interest to nuclear medicine by synthetic melanins.
Topics: Actinium; Adsorption; Bismuth; Cysteine; Dopamine; Gamma Rays; Indium Radioisotopes; Levodopa; Melanins; Nuclear Medicine; Radiochemistry; Scintillation Counting; Tyrosine | 2008 |
The protective effect of hypotaurine and cysteine sulphinic acid on peroxynitrite-mediated oxidative reactions.
Topics: Antioxidants; Cysteine; Dimerization; Dose-Response Relationship, Drug; Glutathione; Humans; Models, Chemical; Nitrites; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxynitrous Acid; Rhodamines; Taurine; Tyrosine | 2008 |
Diagnosis of liver fibrosis using FibroScan and other noninvasive methods in patients with hemochromatosis: a prospective study.
Topics: Age Factors; Aspartate Aminotransferases; Biomarkers; Cohort Studies; Cysteine; Elasticity Imaging Techniques; Female; Ferritins; Follow-Up Studies; Hemochromatosis; Homozygote; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Tyrosine | 2008 |
Characterization of a three-component coupling reaction on proteins by isotopic labeling and nuclear magnetic resonance spectroscopy.
Topics: Carbon Radioisotopes; Chymotrypsinogen; Cysteine; Formaldehyde; Humans; Isotope Labeling; Muramidase; Nuclear Magnetic Resonance, Biomolecular; Papain; Protein Conformation; Proteins; Thioredoxins; Tryptophan; Tyrosine | 2008 |
Tuning the fluorescence response of surface modified CdSe quantum dots between tyrosine and cysteine by addition of p-sulfonatocalix[4]arene.
Topics: Cadmium Compounds; Calixarenes; Cysteine; Fluorescence; Microscopy, Electron, Transmission; Molecular Structure; Phenols; Quantum Dots; Selenium Compounds; Spectrometry, Fluorescence; Surface Properties; Tyrosine | 2008 |
Characterization of the structural and molecular defects in fibres and follicles of the Merino felting lustre mutant.
Topics: Animals; Cysteine; Female; Glycine; Hair Follicle; Keratins; Mutation; Sheep, Domestic; Skin; Tyrosine; Wool | 2009 |
Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation.
Topics: Amino Acid Sequence; Aspartic Acid; Cell Line; Cysteine; Disulfides; Genes, Reporter; Humans; Models, Biological; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Tertiary; Receptors, FSH; Receptors, LH; Tyrosine | 2008 |
LDL protein nitration: implication for LDL protein unfolding.
Topics: Animals; Aorta; Apolipoprotein B-100; Cattle; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Models, Chemical; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Protein Conformation; Protein Denaturation; Protein Processing, Post-Translational; Protein Structure, Secondary; Proteins; Reproducibility of Results; Tyrosine | 2008 |
The significance of disulfide bonding in biological activity of HB-EGF, a mutagenesis approach.
Topics: Animals; Cell Line; Cell Nucleus; Cloning, Molecular; Cysteine; Disulfides; ErbB Receptors; Fibroblasts; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Metallothionein; Mice; Mutagenesis, Site-Directed; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Serine; Tyrosine | 2008 |
Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes.
Topics: Aryldialkylphosphatase; Cysteine; Granulocytes; Humans; Hypochlorous Acid; Lipoproteins, HDL; Plasminogen; Streptokinase; Tyrosine | 2008 |
Cross-link formation of the cysteine 228-tyrosine 272 catalytic cofactor of galactose oxidase does not require dioxygen.
Topics: Catalytic Domain; Copper; Cross-Linking Reagents; Cysteine; Electron Spin Resonance Spectroscopy; Galactose Oxidase; Kinetics; Models, Molecular; Oxygen; Protein Conformation; Spectrophotometry; Tyrosine | 2008 |
Structure of the two transmembrane Cu+ transport sites of the Cu+ -ATPases.
Topics: Adenosine Triphosphatases; Archaeoglobus fulgidus; Binding Sites; Biological Transport; Copper; Cysteine; Histidine; Kinetics; Models, Biological; Molecular Chaperones; Mutagenesis, Site-Directed; Nitrophenols; Organophosphorus Compounds; Protein Transport; Tyrosine; X-Rays | 2008 |
Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms.
Topics: Amino Acids; Crystallography, X-Ray; Cysteine; Hydrogen; Hydrogen Bonding; Hydroxyl Radical; Protein Conformation; Protein Structure, Secondary; Serine; Sulfhydryl Compounds; Threonine; Tyrosine | 2008 |
Comparison of cysteinyl leukotriene concentrations between exhaled breath condensate and bronchoalveolar lavage fluid.
Topics: Biomarkers; Breath Tests; Bronchoalveolar Lavage Fluid; Cysteine; Exhalation; Female; Humans; Idiopathic Pulmonary Fibrosis; Leukotrienes; Lung; Male; Middle Aged; Prospective Studies; Tyrosine; Urea | 2008 |
Inactivation of rabbit muscle glycogen phosphorylase b by peroxynitrite revisited: does the nitration of Tyr613 in the allosteric inhibition site control enzymatic function?
Topics: Allosteric Site; Amino Acid Sequence; Animals; Cysteine; Glycogen Phosphorylase, Muscle Form; Kinetics; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Nitrates; Peptide Fragments; Peroxynitrous Acid; Protein Conformation; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Tyrosine | 2009 |
Cross-linking of a DOPA-containing peptide ligand into its G protein-coupled receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Cell Membrane; Cross-Linking Reagents; Cysteine; Dihydroxyphenylalanine; Immunoblotting; Ligands; Models, Molecular; Oligopeptides; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transformation, Genetic; Tyrosine | 2009 |
Oxidative/nitrative modifications of plasma proteins and thiols from patients with schizophrenia.
Topics: Adult; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Homocysteine; Humans; Male; Oxidative Stress; Schizophrenia; Tyrosine | 2009 |
Identification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome system.
Topics: Amino Acid Sequence; Cells, Cultured; Cysteine; Cysteine Proteinase Inhibitors; Humans; Leupeptins; Nuclear Proteins; Polycomb Repressive Complex 1; Polymorphism, Single Nucleotide; Proteasome Endopeptidase Complex; Protein Denaturation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Repressor Proteins; RING Finger Domains; Transfection; Tyrosine; Ubiquitin | 2009 |
Analysis of oxidative modification of proteins.
Topics: Biochemistry; Biotin; Borohydrides; Cysteine; Isoaspartic Acid; Isotope Labeling; Oxidation-Reduction; Phenylhydrazines; Protein Binding; Proteins; Sulfhydryl Compounds; Tyrosine | 2009 |
Gas-phase IR spectroscopy of deprotonated amino acids.
Topics: Amino Acids; Anions; Aspartic Acid; Cysteine; Gases; Glutamic Acid; Phenylalanine; Protons; Serine; Spectrophotometry; Spectrophotometry, Infrared; Tyrosine | 2009 |
Intramolecular addition of cysteine thiyl radical to phenylalanine and tyrosine in model peptides, Phe (CysS*) and Tyr(CysS*): a computational study.
Topics: Computer Simulation; Cysteine; Models, Molecular; Molecular Conformation; Peptides; Phenylalanine; Quantum Theory; Tyrosine; Water | 2009 |
Electron transfer in peptides with cysteine and methionine as relay amino acids.
Topics: Cysteine; Electron Transport; Methionine; Peptides; Protein Structure, Secondary; Tyrosine; Water | 2009 |
Structural determinants of gating in the TRPV1 channel.
Topics: Amino Acid Sequence; Animals; Capsaicin; Cysteine; Ion Channel Gating; Ions; Leucine; Mesylates; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sensory System Agents; Temperature; TRPV Cation Channels; Tyrosine | 2009 |
Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter.
Topics: Amino Acid Substitution; Cell Line; Cell Membrane; Cysteine; Dipeptides; Extracellular Space; Glutamic Acid; Glycine; Humans; Mutagenesis, Site-Directed; Peptide Transporter 1; Protein Structure, Tertiary; Protein Transport; Symporters; Tyrosine | 2009 |
2.6 A X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase .
Topics: Binding Sites; Cell Cycle Proteins; Crystallography, X-Ray; Cysteine; Drug Design; Enzyme Inhibitors; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Iron; Models, Molecular; Protein Structure, Quaternary; Protein Structure, Secondary; Recombinant Proteins; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Static Electricity; Tumor Suppressor Protein p53; Tyrosine | 2009 |
Tyrosine, cysteine, and S-adenosyl methionine stimulate in vitro [FeFe] hydrogenase activation.
Topics: Bacterial Proteins; Catalytic Domain; Cell-Free System; Chlamydomonas reinhardtii; Cysteine; Escherichia coli; Genetic Vectors; Hydrogen; Hydrogen-Ion Concentration; Hydrogenase; In Vitro Techniques; Iron; Iron-Sulfur Proteins; Models, Chemical; S-Adenosylmethionine; Tyrosine | 2009 |
Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking.
Topics: Anesthetics, Local; Animals; Cells, Cultured; Cerebral Cortex; Cysteine; Golgi Apparatus; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lipoylation; Membrane Proteins; Mice; Mutation; Neurons; Palmitates; Protein Transport; Protein-Tyrosine Kinases; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Transfection; Tritium; Tyrosine | 2009 |
Pathogenic cysteine mutations affect progranulin function and production of mature granulins.
Topics: Animals; Arginine; Axons; Brain; Cell Enlargement; Cell Line, Transformed; Cysteine; Dithiothreitol; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Family Health; Frontotemporal Dementia; Gene Expression Regulation; Genetic Predisposition to Disease; Green Fluorescent Proteins; Humans; Intercellular Signaling Peptides and Proteins; Motor Neurons; Mutation; Neurites; Pancreatic Elastase; Progranulins; Rats; Rats, Wistar; RNA, Messenger; Transfection; Tyrosine | 2010 |
Enhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein-tyrosine phosphatases.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cysteine; Diabetes Mellitus, Type 2; Insulin; Insulin Receptor Substrate Proteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitrogen; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Transfection; Tyrosine | 2010 |
Peroxynitrite-mediated oxidative modifications of complex II: relevance in myocardial infarction.
Topics: Amino Acid Sequence; Animals; Cell Hypoxia; Cyclic N-Oxides; Cysteine; Disulfides; Electron Transport Complex II; Flavin-Adenine Dinucleotide; Humans; Molecular Sequence Data; Molecular Weight; Muscle Cells; Myocardial Infarction; Oxidation-Reduction; Peroxynitrous Acid; Protein Subunits; Rats; Rats, Sprague-Dawley; Tyrosine | 2010 |
Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode.
Topics: Carbon; Cysteine; Electrochemistry; Electrodes; Limit of Detection; Nanofibers; Oxidation-Reduction; Reproducibility of Results; Tryptophan; Tyrosine | 2010 |
Stable isotope labeling method targeting terminal tyrosine for relative peptide quantitation using mass spectrometry.
Topics: Amino Acid Sequence; Chromatography, Liquid; Cysteine; Enkephalin, Leucine; Isotope Labeling; Mass Spectrometry; Molecular Sequence Data; Monophenol Monooxygenase; Neuropeptides; Tyrosine | 2010 |
Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Biological Transport; Blood Pressure; Cysteine; Cystine; Electric Stimulation; Glucose; Glutathione; Heart Rate; Hindlimb; Infusions, Intra-Arterial; Male; Muscle Contraction; Muscle Fatigue; Muscle Strength; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Regional Blood Flow; Time Factors; Tyrosine; Vascular Resistance | 2010 |
Hemochromatosis protein HFE C282Y conformational considerations.
Topics: Amino Acid Substitution; Cysteine; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Membrane Proteins; Mutation; Protein Conformation; Protein Folding; Protein Transport; Tyrosine | 2010 |
Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
Topics: Binding Sites; Blood Proteins; Calcium; Cell Membrane; Crystallography, X-Ray; Cysteine; Factor Xa; Glutamic Acid; Humans; Kinetics; Light; Models, Molecular; Mutation; Phospholipids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Scattering, Radiation; Serpins; Tyrosine | 2010 |
Oxidative posttranslational modifications mediate decreased SERCA activity and myocyte dysfunction in Galphaq-overexpressing mice.
Topics: Animals; Calcium Signaling; Catalase; Cells, Cultured; Cysteine; Disease Models, Animal; Down-Regulation; GTP-Binding Protein alpha Subunits, Gq-G11; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Oxidation-Reduction; Protein Processing, Post-Translational; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tyrosine; Up-Regulation; Ventricular Dysfunction, Left | 2010 |
[The LEOPARD-syndrome].
Topics: Adolescent; Amino Acid Substitution; Chromosomes, Human, Pair 12; Cochlear Implantation; Cysteine; Deafness; Diagnosis, Differential; DNA Mutational Analysis; Exons; Female; Humans; LEOPARD Syndrome; Point Mutation; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Tyrosine | 2010 |
Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal).
Topics: Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Cysteine; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Polymorphism, Single Nucleotide; Portugal; Prevalence; Serine; Tyrosine; Young Adult | 2011 |
L-Carnitine protects plasma components against oxidative alterations.
Topics: Adult; Antioxidants; Blood Proteins; Carnitine; Cysteine; Dietary Supplements; Glutathione; Homocysteine; Humans; Lipid Peroxides; Lipids; Male; Osmolar Concentration; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Protein Carbonylation; Thiobarbituric Acid Reactive Substances; Tyrosine; Young Adult | 2011 |
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant.
Topics: Catalytic Domain; Cysteine; GTP Phosphohydrolases; HEK293 Cells; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation; Protein Binding; Protein Multimerization; Protein Serine-Threonine Kinases; Tyrosine | 2011 |
Nitrosative protein oxidation is modulated during early endotoxemia.
Topics: Animals; Biotin; Blood Pressure; Cysteine; Endotoxemia; Escherichia coli; Heart; HEK293 Cells; Humans; Hypotension; Immunoblotting; In Vitro Techniques; Lipopolysaccharides; Mass Spectrometry; Metalloporphyrins; Mice; Mice, Inbred C57BL; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Peroxynitrous Acid; Protein Processing, Post-Translational; Proteins; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sensitivity and Specificity; Sepsis; Signal Transduction; Telemetry; Tyrosine | 2011 |
Comprehensive analysis of the genes responsible for neuroacanthocytosis in mood disorder and schizophrenia.
Topics: Amino Acid Transport Systems, Neutral; Cysteine; DNA Copy Number Variations; DNA Mutational Analysis; Humans; Japan; Mood Disorders; Neuroacanthocytosis; Schizophrenia; Tyrosine; Vesicular Transport Proteins | 2011 |
Non-alcoholic steatohepatitis (NASH) and oral lichen planus: a rare occurrence.
Topics: Adult; Biopsy, Fine-Needle; Cysteine; Fatty Liver; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histocompatibility Antigens Class I; Humans; Lichen Planus, Oral; Male; Membrane Proteins; Mutation; Siderosis; Tyrosine | 2011 |
Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.
Topics: Arrestins; Caco-2 Cells; Clathrin; Cysteine; Dimerization; Epithelial Cells; Humans; Intestines; Ligands; Phosphorylation; rab5 GTP-Binding Proteins; Receptors, Leukotriene; RNA, Small Interfering; Tyrosine | 2010 |
Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Cyclic AMP; Cysteine; Diabetes Mellitus, Experimental; Exenatide; Hypoglycemic Agents; Male; Mice; Molecular Sequence Data; PC12 Cells; Peptides; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tyrosine; Venoms | 2011 |
Identification of amino acid residues responsible for the release of free drug from an antibody-drug conjugate utilizing lysine-succinimidyl ester chemistry.
Topics: Antibodies, Monoclonal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cysteine; Drug Compounding; Drug Stability; Esters; Hydrolysis; Immunotoxins; Kinetics; Lysine; Models, Chemical; Peptide Mapping; Solubility; Succinimides; Tandem Mass Spectrometry; Technology, Pharmaceutical; Tyrosine; Umbelliferones | 2011 |
Proteinuria in early childhood due to familial LCAT deficiency caused by loss of a disulfide bond in lecithin:cholesterol acyl transferase.
Topics: Adolescent; Anemia, Hemolytic; Angiotensin-Converting Enzyme Inhibitors; Animals; Child; Child, Preschool; Chlorocebus aethiops; Cholesterol, HDL; Corneal Opacity; COS Cells; Cysteine; Disulfides; Diuretics; Female; Genetic Predisposition to Disease; Homozygote; Humans; Lecithin Cholesterol Acyltransferase Deficiency; Male; Mutation; Phosphatidylcholine-Sterol O-Acyltransferase; Proteinuria; Transfection; Treatment Outcome; Tyrosine | 2011 |
Characterization of tyrosine nitration and cysteine nitrosylation modifications by metastable atom-activation dissociation mass spectrometry.
Topics: Amino Acid Sequence; Biochemical Phenomena; Cysteine; Mass Spectrometry; Nitro Compounds; Peptides; Sequence Analysis, Protein; Tyrosine | 2011 |
Requirement for DNA ligase IV during embryonic neuronal development.
Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cerebral Ventricles; Chromosomal Proteins, Non-Histone; Cysteine; DNA Breaks, Double-Stranded; DNA Ligase ATP; DNA Ligases; DNA-Binding Proteins; Embryo, Mammalian; Embryonic Development; Gene Expression Regulation, Developmental; Histones; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Mutation; Neural Stem Cells; Neurons; Protein Serine-Threonine Kinases; Radiation, Ionizing; T-Box Domain Proteins; Tubulin; Tumor Suppressor p53-Binding Protein 1; Tumor Suppressor Proteins; Tyrosine | 2011 |
Two amino acid residues contribute to a cation-π binding interaction in the binding site of an insect GABA receptor.
Topics: Animals; Binding Sites; Cysteine; Female; gamma-Aminobutyric Acid; Hydrogen Bonding; Insect Proteins; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Protein Structure, Tertiary; Protein Subunits; Spodoptera; Tyrosine; Xenopus laevis | 2011 |
Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor.
Topics: Adenosine Triphosphate; Alanine; Animals; Calcium; Calcium Signaling; Cell Line, Transformed; Computer Simulation; Cysteine; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Humans; Ion Channel Gating; Membrane Potentials; Models, Molecular; Mutation; Patch-Clamp Techniques; Permeability; Rats; Receptors, Purinergic P2X3; Silver Nitrate; Transfection; Tyrosine | 2011 |
Branched intermediate formation is the slowest step in the protein splicing reaction of the Ala1 KlbA intein from Methanococcus jannaschii.
Topics: Amino Acid Sequence; Archaeal Proteins; Base Sequence; Cysteine; Dithiothreitol; Exteins; Fluorescent Dyes; Hydrogen-Ion Concentration; Inteins; Kinetics; Methanococcus; Molecular Sequence Data; Peptides; Protein Splicing; Structure-Activity Relationship; Tyrosine | 2011 |
A Korean Parkinson's disease family with the LRRK2 p.Tyr1699Cys mutation showing clinical heterogeneity.
Topics: Age of Onset; Aged; Cysteine; DNA Mutational Analysis; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Republic of Korea; Tyrosine | 2012 |
Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.
Topics: Cysteine; Disulfides; Endoplasmic Reticulum; HEK293 Cells; Humans; Models, Biological; Mutation; Plasmids; Protein Conformation; Protein Folding; Protein Multimerization; Protein Subunits; Serine; Transfection; Tyrosine; von Willebrand Diseases; von Willebrand Factor; Weibel-Palade Bodies | 2012 |
Simultaneous determination of L-cysteine and L-tyrosine using Au-nanoparticles/poly-eriochrome black T film modified glassy carbon electrode.
Topics: Ascorbic Acid; Azo Compounds; Calibration; Carbon; Cysteine; Dopamine; Electric Conductivity; Electrochemistry; Electrodes; Gold; Hydrogen-Ion Concentration; Limit of Detection; Metal Nanoparticles; Microscopy, Electron, Scanning; Oxidation-Reduction; Reproducibility of Results; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Tyrosine; Uric Acid | 2012 |
Role of the Tyr-Cys cross-link to the active site properties of galactose oxidase.
Topics: Catalytic Domain; Cysteine; Galactose Oxidase; Models, Molecular; Tyrosine; X-Ray Absorption Spectroscopy | 2012 |
Interactions of organophosphates with keratins in the cornified epithelium of human skin.
Topics: Binding Sites; Chemical Warfare Agents; Cysteine; Humans; Keratins; Organophosphates; Organothiophosphorus Compounds; Paraoxon; Peptide Fragments; Pronase; Serine; Skin; Tandem Mass Spectrometry; Trypsin; Tyrosine | 2012 |
Facile identification of photocleavable reactive metabolites and oxidative stress biomarkers in proteins via mass spectrometry.
Topics: Amino Acid Sequence; Animals; Chromatography, Liquid; Cysteine; Halogenation; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oxidative Stress; Peptides; Photolysis; Proteins; Proteomics; Tyrosine | 2012 |
Molecular basis of intramolecular electron transfer in proteins during radical-mediated oxidations: computer simulation studies in model tyrosine-cysteine peptides in solution.
Topics: Computer Simulation; Cysteine; Electron Transport; Free Radicals; Kinetics; Molecular Dynamics Simulation; Peptides; Proteins; Quantum Theory; Solutions; Tyrosine; Water | 2012 |
A molecular dynamics investigation on the crizotinib resistance mechanism of C1156Y mutation in ALK.
Topics: Amino Acid Substitution; Anaplastic Lymphoma Kinase; Catalytic Domain; Crizotinib; Crystallography, X-Ray; Cysteine; Drug Design; Drug Resistance, Neoplasm; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Mutation; Protein Conformation; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Tyrosine | 2012 |
Structure and function of ∆1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa.
Topics: Animals; Berberine; Cannabis; Carbon Dioxide; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Intramolecular Oxidoreductases; Mutation; Protein Structure, Tertiary; Psychotropic Drugs; Structure-Activity Relationship; Tyrosine | 2012 |
Identifying proteins that can form tyrosine-cysteine crosslinks.
Topics: Bacterial Proteins; Chromatography, Liquid; Cysteine; Databases, Protein; Metalloproteins; Models, Molecular; Oxidation-Reduction; Protein Conformation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2012 |
Reactive nitrogen oxide species-induced post-translational modifications in human hemoglobin and the association with cigarette smoking.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; Hemoglobins; Humans; Methionine; Molecular Sequence Data; Oxidation-Reduction; Peptides; Peroxynitrous Acid; Protein Processing, Post-Translational; Reactive Nitrogen Species; Smoking; Spectrometry, Mass, Electrospray Ionization; Sulfinic Acids; Tyrosine | 2012 |
Tear fluid small molecular antioxidants profiling shows lowered glutathione in keratoconus.
Topics: Adult; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Contact Lenses; Cornea; Cysteine; Female; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Humans; Keratoconus; Male; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tears; Tyrosine; Uric Acid | 2012 |
Development of (99m)Tc-EC-tyrosine for early detection of breast cancer tumor response to the anticancer drug melphalan.
Topics: Amino Acid Transport System y+L; Animals; Breast Neoplasms; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Ki-67 Antigen; Melphalan; Neoplasm Proteins; Organotechnetium Compounds; Radionuclide Imaging; Rats; Rats, Inbred F344; Tissue Distribution; Treatment Outcome; Tyrosine | 2013 |
Brodifacoum is effective against Norway rats (Rattus norvegicus) in a tyrosine139cysteine focus of anticoagulant resistance in Westphalia, Germany.
Topics: 4-Hydroxycoumarins; Amino Acid Substitution; Animals; Anticoagulants; Cysteine; Drug Resistance; Germany; Mixed Function Oxygenases; Rats; Rodent Control; Rodenticides; Sequence Analysis, DNA; Tyrosine; Vitamin K Epoxide Reductases | 2012 |
Metabolic response to oral microcystin-LR exposure in the rat by NMR-based metabonomic study.
Topics: Animals; Choline; Cysteine; Glutathione; Ileum; Inactivation, Metabolic; Liver; Magnetic Resonance Spectroscopy; Male; Marine Toxins; Metabolome; Metabolomics; Microcystins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Toxicity Tests; Tyrosine | 2012 |
The role of amino acids in spina bifida.
Topics: Adult; Alanine; Amino Acids; Amniocentesis; Amniotic Fluid; Cystathionine; Cysteine; Female; Gestational Age; Humans; Phenylalanine; Pregnancy; Pregnancy Trimester, Second; Spinal Dysraphism; Tryptophan; Tyrosine; Ultrasonography, Prenatal | 2012 |
Probing the function of the Tyr-Cys cross-link in metalloenzymes by the genetic incorporation of 3-methylthiotyrosine.
Topics: Animals; Catalytic Domain; Cysteine; Cysteine Dioxygenase; Cytochromes a1; Cytochromes c1; Galactose Oxidase; Mutagenesis, Site-Directed; Myoglobin; Nitrate Reductases; Oxidation-Reduction; Sulfite Reductase (Ferredoxin); Tyrosine; Whales | 2013 |
The radical SAM enzyme spore photoproduct lyase employs a tyrosyl radical for DNA repair.
Topics: Cysteine; DNA Repair; Geobacillus; Models, Chemical; Proteins; Spores, Bacterial; Thymidine; Tyrosine | 2013 |
A single mutation within a Ca(2+) binding loop increases proteolytic activity, thermal stability, and surfactant stability.
Topics: Alkalies; Amino Acid Sequence; Amino Acid Substitution; Bacillus; Bacterial Proteins; Binding Sites; Calcium; Cysteine; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Proteolysis; Sequence Homology, Amino Acid; Serine Endopeptidases; Surface-Active Agents; Temperature; Tyrosine | 2013 |
Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Atherosclerosis; Cell Cycle Proteins; Cysteine; Female; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Free Radical Scavengers; Hematopoietic Stem Cells; Insulin; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Neutrophils; Nitrogen; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Tyrosine | 2013 |
Metabolic changes and DNA hypomethylation in cerebellum are associated with behavioral alterations in mice exposed to trichloroethylene postnatally.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebellum; Cysteine; DNA Methylation; Glutathione; Male; Mice; Mice, Inbred MRL lpr; Oxidation-Reduction; Oxidative Stress; Trichloroethylene; Tyrosine | 2013 |
Is the oxidant/antioxidant status altered in CADASIL patients?
Topics: Adult; Antioxidants; CADASIL; Case-Control Studies; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Oxidants; Oxidation-Reduction; Oxidative Stress; Tyrosine | 2013 |
Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy.
Topics: Amino Acid Motifs; Animals; Binding Sites; Cell Line; Cell Proliferation; CSK Tyrosine-Protein Kinase; Cysteine; Gene Expression Regulation; Membrane Proteins; Mice; Molecular Sequence Data; Muscular Diseases; Mutation; Myoblasts; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; src-Family Kinases; Tyrosine | 2013 |
A single amino acid determines the catalytic efficiency of two alkenal double bond reductases produced by the liverwort Plagiochasma appendiculatum.
Topics: Aldehydes; Amino Acid Sequence; Biocatalysis; Cysteine; Escherichia coli; Hepatophyta; Kinetics; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Phylogeny; Plant Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2013 |
A nucleolar AAA-NTPase is required for parasite division.
Topics: Adenosine Triphosphatases; Amino Acid Substitution; Cell Cycle Proteins; Cell Division; Cell Nucleolus; Cysteine; Evolution, Molecular; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Genetic Complementation Test; Hot Temperature; Molecular Sequence Data; Mutagenesis; Phylogeny; Protozoan Proteins; Ribosomes; RNA, Ribosomal, 28S; Toxoplasma; Tyrosine; Valosin Containing Protein | 2013 |
Covalent bond formation between amino acids and lignin: cross-coupling between proteins and lignin.
Topics: Amino Acids; Cell Wall; Chromatography, High Pressure Liquid; Cysteine; Horseradish Peroxidase; Hydrogen Peroxide; Indolequinones; Lignin; Nuclear Magnetic Resonance, Biomolecular; Phenols; Proteins; Threonine; Tyrosine | 2013 |
Iron(IV)hydroxide pK(a) and the role of thiolate ligation in C-H bond activation by cytochrome P450.
Topics: Carbon; Catalysis; Cysteine; Cytochrome P-450 Enzyme System; Enzyme Activation; Hydrogen Bonding; Hydroxides; Oxidation-Reduction; Tryptophan; Tyrosine | 2013 |
Second-sphere interactions between the C93-Y157 cross-link and the substrate-bound Fe site influence the O₂ coupling efficiency in mouse cysteine dioxygenase.
Topics: Amino Acid Substitution; Animals; Apoenzymes; Binding Sites; Biocatalysis; Catalytic Domain; Cysteine; Cysteine Dioxygenase; Enzyme Inhibitors; Holoenzymes; Iron; Kinetics; Mice; Models, Molecular; Mutant Proteins; Oxidation-Reduction; Oxygen; Protein Processing, Post-Translational; Recombinant Proteins; Tyrosine | 2013 |
The role of protein characteristics in the formation and fluorescence of Au nanoclusters.
Topics: Amines; Amino Acids; Animals; Biocompatible Materials; Cattle; Cysteine; Ferric Compounds; Gold; Ligands; Metal Nanoparticles; Muramidase; Nanotechnology; Pepsin A; Proteins; Serum Albumin, Bovine; Solubility; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Trypsin; Tryptophan; Tyrosine; Water | 2014 |
Carboplatin-induced Fanconi-like syndrome in rats: amelioration by pentoxifylline.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Carboplatin; Creatinine; Cysteine; Female; Glutathione; Hypersensitivity, Delayed; Immunologic Deficiency Syndromes; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Pancytopenia; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Skin Neoplasms; Tyrosine; Uric Acid | 2014 |
Tyrosine/cysteine cluster sensitizing human γD-crystallin to ultraviolet radiation-induced photoaggregation in vitro.
Topics: Amino Acid Substitution; Cataract; Cysteine; gamma-Crystallins; Humans; Lens, Crystalline; Protein Denaturation; Protein Folding; Protein Structure, Quaternary; Tryptophan; Tyrosine; Ultraviolet Rays | 2014 |
Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics.
Topics: Adenosine Triphosphatases; Animals; Animals, Genetically Modified; Cells, Cultured; Cysteine; Disease Models, Animal; Drosophila; Drosophila Proteins; Female; Gene Expression Regulation; Green Fluorescent Proteins; Haploinsufficiency; Humans; Locomotion; Male; Microtubules; Mutation; Neurons; Nocodazole; Rats; Spastic Paraplegia, Hereditary; Spastin; Transfection; Tubulin Modulators; Tyrosine | 2014 |
Water promoting electron hole transport between tyrosine and cysteine in proteins via a special mechanism: double proton coupled electron transfer.
Topics: Cysteine; Electron Transport; Models, Molecular; Protein Structure, Secondary; Proteins; Protons; Quantum Theory; Ribonucleotide Reductases; Tyrosine; Water | 2014 |
Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolec
Topics: Animals; Binding Sites; Blotting, Western; Catalytic Domain; Chagas Disease; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Activation; Host-Parasite Interactions; Isoenzymes; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nitrates; Peroxynitrous Acid; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Reactive Oxygen Species; Superoxide Dismutase; Trypanosoma cruzi; Tyrosine | 2014 |
Traceless chemical ligation from S-, O-, and N-acyl isopeptides.
Topics: Acylation; Biochemistry; Cysteine; Homocysteine; Peptides; Peptides, Cyclic; Serine; Solid-Phase Synthesis Techniques; Tryptophan; Tyrosine | 2014 |
Low serum ferroxidase I activity is associated with mortality in heart failure and related to both peroxynitrite-induced cysteine oxidation and tyrosine nitration of ceruloplasmin.
Topics: Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Case-Control Studies; Ceruloplasmin; Cohort Studies; Cysteine; Female; Follow-Up Studies; Heart Failure; Humans; Male; Natriuretic Peptide, Brain; Norepinephrine; Oxidation-Reduction; Peroxynitrous Acid; Prognosis; Proportional Hazards Models; Survival Rate; Tyrosine | 2014 |
s-Methyl cysteine enhanced survival of nerve growth factor differentiated PC12 cells under hypoxic conditions.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Caspase 8; Cell Differentiation; Cell Survival; Cysteine; DNA Fragmentation; Dose-Response Relationship, Drug; Glutathione Peroxidase; Glutathione Reductase; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Indazoles; Membrane Potential, Mitochondrial; Nerve Growth Factor; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Pyridines; Pyrrolidines; Rats; Reactive Oxygen Species; Thiocarbamates; Tyrosine; Up-Regulation | 2014 |
Leopard syndrome caused by heterozygous missense mutation of Tyr 279 Cys in the PTPN11 gene in a sporadic case of Chinese Han.
Topics: Adolescent; Asian People; Cysteine; Heterozygote; Humans; LEOPARD Syndrome; Male; Mutation, Missense; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Tyrosine | 2014 |
Copper futures: ceruloplasmin and heart failure.
Topics: Ceruloplasmin; Cysteine; Female; Heart Failure; Humans; Male; Peroxynitrous Acid; Tyrosine | 2014 |
Linkage analysis and exome sequencing identify a novel mutation in KCTD7 in patients with progressive myoclonus epilepsy with ataxia.
Topics: Adolescent; Ataxia; Child, Preschool; Chromosome Mapping; Chromosomes, Human, Pair 7; Cysteine; Electroencephalography; Exome; Female; Genetic Linkage; Humans; Infant; Male; Mutation; Myoclonic Epilepsies, Progressive; Potassium Channels; Tyrosine | 2014 |
Bioinspired strategy for the ribosomal synthesis of thioether-bridged macrocyclic peptides in bacteria.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Cyclization; Cysteine; Escherichia coli; Inteins; Molecular Sequence Data; Mutation; Peptides; Peptides, Cyclic; Protein Biosynthesis; Protein Processing, Post-Translational; Protein Splicing; Tyrosine | 2014 |
Rationalization of the pKa values of alcohols and thiols using atomic charge descriptors and its application to the prediction of amino acid pKa's.
Topics: Alcohols; Cysteine; Models, Chemical; Phenols; Proteins; Quantum Theory; Serine; Static Electricity; Sulfhydryl Compounds; Thermodynamics; Tyrosine; Water | 2014 |
Reactivity of hypotaurine and cysteine sulfinic acid toward carbonate radical anion and nitrogen dioxide as explored by the peroxidase activity of Cu,Zn superoxide dismutase and by pulse radiolysis.
Topics: Animals; Carbonates; Cattle; Chromatography, High Pressure Liquid; Cysteine; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radicals; Hydrogen Peroxide; Nitrogen Dioxide; Oxidants; Oxidation-Reduction; Peroxidases; Pulse Radiolysis; Superoxide Dismutase; Taurine; Tyrosine | 2014 |
Lignin cross-links with cysteine- and tyrosine-containing peptides under biomimetic conditions.
Topics: Biomimetics; Cross-Linking Reagents; Cysteine; Lignin; Magnetic Resonance Spectroscopy; Molecular Structure; Peptides; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2014 |
Curcumin could reduce the monomer of TTR with Tyr114Cys mutation via autophagy in cell model of familial amyloid polyneuropathy.
Topics: Amyloid Neuropathies, Familial; Autophagy; Cell Proliferation; Cell Survival; Curcumin; Cysteine; HEK293 Cells; Humans; Mutation; Prealbumin; Tyrosine | 2014 |
The Cys-Tyr cross-link of cysteine dioxygenase changes the optimal pH of the reaction without a structural change.
Topics: Amino Acid Substitution; Animals; Catalysis; Crystallography, X-Ray; Cysteine; Cysteine Dioxygenase; Hydrogen-Ion Concentration; Mutation, Missense; Protein Structure, Secondary; Rats; Tyrosine | 2014 |
Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex.
Topics: Animals; Calcium Chloride; CHO Cells; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Ileum; KATP Channels; Mice; Molsidomine; Muscle Contraction; Muscle, Smooth; Mutation; Peroxynitrous Acid; Protein Processing, Post-Translational; Signal Transduction; Sulfides; Sulfonylurea Receptors; Transfection; Tyrosine | 2015 |
Expanding the phenotypic expression of Sonic Hedgehog mutations beyond holoprosencephaly.
Topics: Adenine; Cysteine; Female; Gene Expression; Guanine; Hedgehog Proteins; Holoprosencephaly; Humans; Infant; Male; Mutation; Pedigree; Penetrance; Phenotype; Tyrosine | 2015 |
T cell tyrosine phosphorylation response to transient redox stress.
Topics: Cysteine; Humans; Immunity, Innate; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Reactive Oxygen Species; Syk Kinase; T-Lymphocytes; Tyrosine | 2015 |
GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.
Topics: Animals; Apoptosis; Autophagy; Caspase 3; Cell Line; Cysteine; Gene Expression; Gene Knockdown Techniques; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Knockout; Protein Phosphatase 1; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tyrosine | 2015 |
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Topics: Adenine; Adult; Alleles; Alveolar Process; Amino Acid Sequence; Animals; Cathepsin K; Chlorocebus aethiops; Codon, Terminator; Conserved Sequence; COS Cells; Cysteine; Dental Cementum; Guanine; Heterozygote; Humans; Male; Models, Genetic; Mutation, Missense; Pedigree; Phenol; Pycnodysostosis; Radiography, Panoramic; Tooth Abnormalities; Tryptophan; Tyrosine; X-Ray Microtomography | 2015 |
Development of radioiodine-labeled 4-hydroxyphenylcysteamine for specific diagnosis of malignant melanoma.
Topics: Animals; Cysteine; Iodine Radioisotopes; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured; Tyrosine | 2015 |
DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Topics: Adolescent; Adult; Child; Child, Preschool; Cysteine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dynactin Complex; Female; Genetic Predisposition to Disease; Humans; Incidence; Infant; Male; Middle Aged; Mutation, Missense; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Sex Factors; Tyrosine; Young Adult | 2016 |
Elevated serum levels of cysteine and tyrosine: early biomarkers in asymptomatic adults at increased risk of developing metabolic syndrome.
Topics: Adult; Biomarkers; Cysteine; Early Diagnosis; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Prevalence; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity; Slovenia; Tyrosine | 2015 |
Oxidation of Hypotaurine and Cysteine Sulfinic Acid by Peroxidase-generated Reactive Species.
Topics: Cysteine; Hydrogen Peroxide; Nitrites; Nitrosation; Oxidation-Reduction; Peroxidase; Reactive Oxygen Species; Sulfinic Acids; Sulfonium Compounds; Taurine; Tyrosine | 2015 |
The effects of tissue-non-specific alkaline phosphatase gene therapy on craniosynostosis and craniofacial morphology in the FGFR2C342Y/+ mouse model of Crouzon craniosynostosis.
Topics: Alkaline Phosphatase; Animals; Calcification, Physiologic; Calcium; Cephalometry; Cranial Sutures; Craniosynostoses; Cysteine; Disease Models, Animal; Female; Genetic Therapy; Genetic Vectors; Lentivirus; Male; Mice; Mice, Inbred BALB C; Occipital Bone; Parietal Bone; Phosphorus; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; Skull; Tyrosine; X-Ray Microtomography | 2015 |
The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine.
Topics: Amino Acid Motifs; Catalysis; Crystallography, X-Ray; Cysteine; Disulfides; Dyrk Kinases; Humans; Models, Molecular; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Staurosporine; Substrate Specificity; Tyrosine | 2015 |
Gas-phase tyrosine-to-cysteine radical migration in model systems.
Topics: Computer Simulation; Cysteine; Free Radicals; Gases; Models, Chemical; Peptides; Phase Transition; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2015 |
Cysteine as a ligand platform in the biosynthesis of the FeFe hydrogenase H cluster.
Topics: Catalysis; Catalytic Domain; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Hydrogenase; Iron; Iron-Sulfur Proteins; Ligands; Methionine; Potassium Cyanide; Protein Binding; Protons; Solar Energy; Trans-Activators; Tyrosine | 2015 |
Increased Hydrolysis of Oximino-β-Lactams by CMY-107, a Tyr199Cys Mutant Form of CMY-2 Produced by Escherichia coli.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Cysteine; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Gene Expression; Genetic Loci; Humans; Hydrolysis; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Multilocus Sequence Typing; Mutation; Plasmids; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Tyrosine | 2015 |
Simultaneous determination of cysteine, uric acid and tyrosine using Au-nanoparticles/poly(E)-4-(p-tolyldiazenyl)benzene-1,2,3-triol film modified glassy carbon electrode.
Topics: Coated Materials, Biocompatible; Cysteine; Electrodes; Gold; Humans; Membranes, Artificial; Metal Nanoparticles; Tyrosine; Uric Acid | 2016 |
S-Sulfocysteine simplifies fed-batch processes and increases the CHO specific productivity via anti-oxidant activity.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Antioxidants; Batch Cell Culture Techniques; Bioreactors; CHO Cells; Cricetinae; Cricetulus; Culture Media; Cysteine; Glutathione; Glycosylation; Hydrogen-Ion Concentration; Peptide Mapping; Tyrosine | 2016 |
CO and CN- syntheses by [FeFe]-hydrogenase maturase HydG are catalytically differentiated events.
Topics: Carbon Monoxide; Catalysis; Catalytic Domain; Cyanides; Cysteine; Desulfovibrio desulfuricans; Homocysteine; Hydrogenase; Iron-Sulfur Proteins; Ligands; Protein Structure, Secondary; S-Adenosylmethionine; Tyrosine | 2016 |
Further studies on the role of the residue 890 cysteine to tyrosine mutation in the M70 primase ORF of the temperature-sensitive mutant (tsm5) of murine cytomegalovirus.
Topics: Amino Acid Sequence; Animals; Cell Line; Cysteine; DNA Primase; DNA Replication; DNA, Viral; Fibroblasts; Macrophages; Metagenomics; Mice; Muromegalovirus; Mutation; Open Reading Frames; Phenotype; Temperature; Tyrosine; Virus Replication | 2016 |
The cysteine, total sulfur amino acid, tyrosine, phenylalanine + tyrosine, and non-essential amino acid maintenance requirements of broiler breeders.
Topics: Amino Acids; Amino Acids, Sulfur; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Female; Nutritional Requirements; Phenylalanine; Random Allocation; Tyrosine | 2016 |
How Far Does a Receptor Influence Vibrational Properties of an Odorant?
Topics: Acetophenones; Computer Simulation; Crystallography, X-Ray; Cysteine; Electrons; Humans; Molecular Conformation; Molecular Dynamics Simulation; Odorants; Olfactory Receptor Neurons; Opsins; Pentanols; Receptors, Odorant; Smell; Spectrophotometry, Infrared; Tyrosine; Vibration | 2016 |
Methotrexate administration induces differential and selective protein tyrosine nitration and cysteine nitrosylation in the subcellular organelles of the small intestinal mucosa of rats.
Topics: Animals; Blotting, Western; Cysteine; Cytosol; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Mitochondrial Proteins; Nuclear Proteins; Proteins; Rats; Rats, Wistar; Tyrosine | 2016 |
Evaluation of Antioxidant or Prooxidant Properties of Selected Amino Acids Using In Vitro Assays and in Oil-in-Water Emulsions Under Riboflavin Sensitization.
Topics: Amino Acids; Antioxidants; Cysteine; Emulsions; Lipid Peroxidation; Lipid Peroxides; Oxidants; Oxidation-Reduction; Reactive Oxygen Species; Riboflavin; Tryptophan; Tyrosine; Water | 2016 |
Stabilizing the cold plasma-stimulated medium by regulating medium's composition.
Topics: Antineoplastic Agents; Culture Media; Cysteine; Free Radicals; Freezing; Helium; Humans; Hydrogen Peroxide; Methionine; Neoplasms; Radiation; Tyrosine | 2016 |
Identification of Connexin43 Phosphorylation and S-Nitrosylation in Cultured Primary Vascular Cells.
Topics: Biotin; Blotting, Western; Cells, Cultured; Connexin 43; Cysteine; Fluorescent Antibody Technique; Human Umbilical Vein Endothelial Cells; Humans; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; S-Nitrosothiols; Serine; Threonine; Tyrosine | 2016 |
Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.
Topics: Animals; Crystallography, X-Ray; Cysteine; Cysteine Dioxygenase; Enzyme Inhibitors; Mammals; Models, Molecular; Mutant Proteins; Protein Binding; Protein Conformation; Tyrosine | 2016 |
Modification of human serum albumin by the nerve agent VX: microbore liquid chromatography/electrospray ionization high-resolution time-of-flight tandem mass spectrometry method for detection of phosphonylated tyrosine and novel cysteine containing disulf
Topics: Cysteine; Disulfides; Humans; Nerve Agents; Organothiophosphorus Compounds; Phosphorylation; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tyrosine | 2016 |
A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains.
Topics: Amino Acid Substitution; Animals; Antimicrobial Cationic Peptides; Bacterial Proteins; Cathelicidins; Cell Line; Cysteine; Disease Models, Animal; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Phenotype; Point Mutation; Protein Binding; Protein Kinases; Staphylococcal Skin Infections; Tyrosine; Viral Tropism | 2016 |
Analysis of Chlorination, Nitration, and Nitrosylation of Tyrosine and Oxidation of Methionine and Cysteine in Hemoglobin from Type 2 Diabetes Mellitus Patients by Nanoflow Liquid Chromatography Tandem Mass Spectrometry.
Topics: Adult; Aged; Amino Acid Sequence; Cysteine; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Halogenation; Hemoglobins; Humans; Male; Methionine; Middle Aged; Nitrates; Nitroso Compounds; Oxidation-Reduction; Tyrosine | 2016 |
Co-distribution of cysteine cathepsins and matrix metalloproteases in human dentin.
Topics: Cathepsin K; Cathepsins; Cysteine; Dentin; Enzyme Assays; Epoxy Compounds; Humans; Immunohistochemistry; Kinetics; Leucine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Peptide Hydrolases; Tyrosine | 2017 |
Active-site maturation and activity of the copper-radical oxidase GlxA are governed by a tryptophan residue.
Topics: Amino Acid Motifs; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalytic Domain; Cations, Divalent; Cloning, Molecular; Copper; Crystallography, X-Ray; Cysteine; Escherichia coli; Fusarium; Galactose Oxidase; Gene Expression; Kinetics; Ligands; Mutation; Oxidoreductases; Protein Binding; Protein Domains; Protein Structure, Secondary; Recombinant Proteins; Streptomyces lividans; Structural Homology, Protein; Substrate Specificity; Tryptophan; Tyrosine | 2017 |
Pheomelanogenesis is promoted at a weakly acidic pH.
Topics: Acids; Cysteine; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Melanins; Melanosomes; Monophenol Monooxygenase; Oxidation-Reduction; Time Factors; Tyrosine | 2017 |
Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.
Topics: Amino Acid Transport System L; Amino Acids, Cyclic; Animals; Benzoxazoles; Cell Adhesion; Cysteine; Endothelial Cells; Erythrocyte Deformability; Erythrocytes; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Leucine; Mice; Mice, Nude; Reticulocytes; RNA, Messenger; S-Nitrosothiols; Tyrosine | 2017 |
The Iron Chaperone Protein CyaY from Vibrio cholerae Is a Heme-Binding Protein.
Topics: Amino Acid Motifs; Bacterial Proteins; Binding Sites; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Heme; Hemeproteins; Ion Transport; Iron; Kinetics; Models, Molecular; Molecular Chaperones; Mutation; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Secondary; Recombinant Proteins; Tyrosine; Vibrio cholerae | 2017 |
Tyrosine or Tryptophan? Modifying a Metalloradical Catalytic Site by Removal of the Cys-Tyr Cross-Link in the Galactose 6-Oxidase Homologue GlxA.
Topics: Algorithms; Catalytic Domain; Copper; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Galactose Oxidase; Oxidation-Reduction; Tryptophan; Tyrosine | 2017 |
Understanding the Reactivity of CO
Topics: Amino Acids; Carbonates; Cysteine; Electron Transport; Free Radicals; Histidine; Hydrogen; Methionine; Nitric Oxide; Phenylalanine; Sulfur; Tryptophan; Tyrosine | 2017 |
Dynamic roles for the N-terminus of the yeast G protein-coupled receptor Ste2p.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Dimerization; Ligands; Protein Binding; Receptors, G-Protein-Coupled; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Tyrosine | 2017 |
Protein oxidation involved in Cys-Tyr post-translational modification.
Topics: Cysteine; Oxidation-Reduction; Oxidoreductases; Protein Processing, Post-Translational; Tyrosine | 2017 |
Orthogonal Tyrosine and Cysteine Site-Directed Spin Labeling for Dipolar Pulse EPR Spectroscopy on Proteins.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Electrons; Models, Molecular; Nitrogen Oxides; Proteins; Spin Labels; Tyrosine | 2017 |
Keratin-water-NMF interaction as a three layer model in the human stratum corneum using in vivo confocal Raman microscopy.
Topics: Adult; Cysteine; Disulfides; Epidermis; Female; Humans; Hydrogen Bonding; Keratins; Male; Microscopy, Confocal; Middle Aged; Models, Biological; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrum Analysis, Raman; Tyrosine; Water; Young Adult | 2017 |
Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin.
Topics: Acetylcholinesterase; Catalysis; Chemical Warfare Agents; Cysteine; Disulfides; Dose-Response Relationship, Drug; Humans; Kinetics; Models, Molecular; Nerve Agents; Organothiophosphorus Compounds; Phosphorylation; Serum Albumin, Human; Tandem Mass Spectrometry; Tyrosine | 2018 |
Use of a Tyrosine Analogue To Modulate the Two Activities of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis, Cysteine Oxidation versus Oxidative C-S Bond Formation.
Topics: Catalysis; Catalytic Domain; Cysteine; Methylhistidines; Molecular Structure; Nonheme Iron Proteins; Oxidation-Reduction; Sulfhydryl Compounds; Tyrosine | 2018 |
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Cysteine; HEK293 Cells; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Mutation, Missense; Point Mutation; Protein Binding; Protein Conformation; Tyrosine; Vitamin K Epoxide Reductases; Warfarin | 2018 |
Cofactor Biogenesis in Cysteamine Dioxygenase: C-F Bond Cleavage with Genetically Incorporated Unnatural Tyrosine.
Topics: Amino Acid Motifs; Carbon; Catalytic Domain; Cysteine; Cysteine Dioxygenase; Dioxygenases; Fluorine; Humans; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Structure, Tertiary; Tyrosine | 2018 |
Multifunctional, High Molecular Weight, Post-Translationally Modified Proteins through Oxidative Cysteine Coupling and Tyrosine Modification.
Topics: Alkynes; Amino Acid Sequence; Azides; Click Chemistry; Cycloaddition Reaction; Cysteine; Elastin; Escherichia coli; Gene Expression; Oxidative Coupling; Peptides; Polymerization; Protein Processing, Post-Translational; Tyrosine | 2018 |
Living with Oxygen.
Topics: Catalytic Domain; Coordination Complexes; Cysteine; Cytochrome P-450 Enzyme System; Heme; Metals, Heavy; Methionine; Oxidation-Reduction; Oxygen; Protein Structural Elements; Tryptophan; Tyrosine | 2018 |
The achievement of boar sperm in vitro capacitation is related to an increase of disrupted disulphide bonds and intracellular reactive oxygen species levels.
Topics: Acrosome Reaction; Animals; Calcium; Cysteine; Disulfides; DNA Fragmentation; Exocytosis; Female; Fertilization in Vitro; Glutathione; Male; Membrane Lipids; Membrane Potential, Mitochondrial; Peroxides; Phosphorylation; Reactive Oxygen Species; Sperm Capacitation; Sperm Motility; Spermatozoa; Superoxides; Swine; Tyrosine | 2018 |
Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT.
Topics: Binding Sites; Cations, Monovalent; Cell Membrane; Cysteine; Cytoplasm; Escherichia coli; Escherichia coli Proteins; Molecular Dynamics Simulation; Mutation; Plasma Membrane Neurotransmitter Transport Proteins; Protein Binding; Protein Domains; Sodium; Transcytosis; Tyrosine | 2018 |
Proteomic Identification of Protein Tyrosine Phosphatase and Substrate Interactions in Living Mammalian Cells by Genetic Encoding of Irreversible Enzyme Inhibitors.
Topics: Cross-Linking Reagents; Cysteine; Enzyme Inhibitors; HEK293 Cells; Humans; Phosphorylation; Proof of Concept Study; Protein Engineering; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proteomics; Receptor, ErbB-2; Tyrosine | 2018 |
A facile route to prepare functional mesoporous organosilica spheres with electroactive units for chiral recognition of amino acids.
Topics: Amino Acids; Cyclohexylamines; Cysteine; Electrochemical Techniques; Ionic Liquids; Porosity; Silicon Dioxide; Stereoisomerism; Tryptophan; Tyrosine | 2019 |
A computational investigation of the reactions of tyrosyl, tryptophanyl, and cysteinyl radicals with nitric oxide and molecular oxygen.
Topics: Cysteine; Density Functional Theory; Diffusion; Free Radicals; Molecular Structure; Nitric Oxide; Oxidation-Reduction; Oxygen; Tryptophan; Tyrosine | 2019 |
Detection of HLA-C*07:595, an HLA-C*07 variant, in a Taiwanese hematopoietic stem cell donor.
Topics: Alleles; Codon; Cysteine; Exons; Genetic Variation; Haplotypes; Hematopoietic Stem Cells; Histocompatibility Testing; HLA-C Antigens; Humans; Sequence Analysis, DNA; Taiwan; Tissue Donors; Tyrosine | 2019 |
Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Topics: Catalytic Domain; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Cysteine Dioxygenase; Dipeptides; Electron Spin Resonance Spectroscopy; Humans; Models, Molecular; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Tyrosine | 2019 |
Ultrafast photoinduced flavin dynamics in the unusual active site of the tRNA methyltransferase TrmFO.
Topics: Adenine; Amino Acid Sequence; Bacillus subtilis; Binding Sites; Cysteine; Flavin-Adenine Dinucleotide; Flavins; Kinetics; Models, Molecular; Oxidation-Reduction; Photochemical Processes; Protein Binding; tRNA Methyltransferases; Tyrosine | 2019 |
Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Topics: Amino Acid Substitution; Amino Acids; Carrier Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Humans; Isoenzymes; Ligands; Membrane Proteins; Models, Molecular; Mutant Proteins; Phosphoenolpyruvate; Protein Binding; Protein Conformation; Serine; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tyrosine | 2019 |
Syntheses of Atypically Fluorinated Peptidyl Macrocycles through Sequential Vinylic Substitutions.
Topics: Cysteine; Histidine; Humans; Macrocyclic Compounds; Peptides; Serine; Tyrosine; Vinyl Compounds | 2020 |
Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine.
Topics: Amino Acid Substitution; Animals; Cysteine; Female; Glycine; Hydrogen Bonding; Keratins; Polymorphism, Single Nucleotide; Protein Domains; Sheep; Tyrosine; Wool; Wool Fiber | 2019 |
Oxidation of myofibrillar proteins induced by peroxyl radicals: Role of oxidizable amino acids.
Topics: Amino Acids; Carrier Proteins; Cysteine; Electrophoresis, Polyacrylamide Gel; Meat Proteins; Methionine; Oxidation-Reduction; Peroxides; Tryptophan; Tyrosine | 2019 |
Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds: the fluorescence of the protein is conserved only towards peroxyl radicals.
Topics: Amidines; Chromatography, Liquid; Cysteine; Dipeptides; Free Radicals; Green Fluorescent Proteins; Oxidation-Reduction; Oxidative Stress; Tandem Mass Spectrometry; Tyrosine; Water | 2020 |
Entropy based analysis of vertebrate sperm protamines sequences: evidence of potential dityrosine and cysteine-tyrosine cross-linking in sperm protamines.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computational Biology; Conserved Sequence; Cysteine; DNA; Entropy; Eutheria; Male; Protamines; Protein Binding; Protein Folding; Sequence Alignment; Spermatozoa; Tyrosine | 2020 |
Cleavage of Disulfide Bonds in Cystine by UV-B Illumination Mediated by Tryptophan or Tyrosine as Photosensitizers.
Topics: Cysteine; Cystine; Disulfides; Oxidation-Reduction; Photolysis; Photosensitizing Agents; Tryptophan; Tyrosine; Ultraviolet Rays | 2020 |
Efficient synthesis of amino acids capped gold nanoparticles from easily reducible aryldiazonium tetrachloroaurate(III) salts for cellular uptake study.
Topics: Amino Acids; Chlorides; Cysteine; Electrophoresis, Agar Gel; Gold Compounds; HeLa Cells; Humans; Metal Nanoparticles; Tryptophan; Tyrosine | 2020 |
Clinical Penetrance of Hereditary Hemochromatosis-Related End-Organ Damage of C282Y Homozygosity, A Newfoundland Experience.
Topics: Adult; Cysteine; Disease Progression; Female; Follow-Up Studies; Genetic Testing; Hemochromatosis; Hemochromatosis Protein; Hemosiderosis; Homozygote; Humans; Iron; Liver Cirrhosis; Male; Middle Aged; Newfoundland and Labrador; Penetrance; Retrospective Studies; Tyrosine | 2020 |
Functional analysis of cysteine residues of the Hok/Gef type I toxins in Escherichia coli.
Topics: Bacterial Toxins; Cysteine; Escherichia coli; Escherichia coli Proteins; Microbial Viability; Mutation; Periplasm; Toxin-Antitoxin Systems; Tyrosine | 2021 |
Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine.
Topics: Biocompatible Materials; Cysteine; Gold; Materials Testing; Metal Nanoparticles; Molecular Structure; Particle Size; Phenylalanine; Spectrum Analysis, Raman; Stereoisomerism; Tyrosine; Vibration | 2021 |
Whey protein concentrate protects against age-dependent alteration in redox biomarkers.
Topics: Aging; Animals; Biomarkers; Cysteine; Drug Evaluation, Preclinical; Erythrocytes; Glycation End Products, Advanced; Lipid Metabolism; Male; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Tryptophan; Tyrosine; Whey Proteins | 2020 |
Redox status of cysteines does not alter functional properties of human dUTPase but the Y54C mutation involved in monogenic diabetes decreases protein stability.
Topics: Amino Acid Substitution; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Diabetes Mellitus; Humans; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Point Mutation; Protein Stability; Pyrophosphatases; Recombinant Proteins; Tyrosine | 2021 |
The Crystal Structure of Cysteamine Dioxygenase Reveals the Origin of the Large Substrate Scope of This Vital Mammalian Enzyme.
Topics: Animals; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dioxygenases; Humans; Iron; Mice; Molecular Dynamics Simulation; Peptides; Protein Conformation; Quantum Theory; Substrate Specificity; Tyrosine | 2021 |
Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins.
Topics: Caseins; Cysteine; Glutathione; Oxidation-Reduction; Proteomics; Tyrosine | 2022 |
Role of Water in Proton-Coupled Electron Transfer between Tyrosine and Cysteine in Ribonucleotide Reductase.
Topics: Cysteine; Electron Transport; Electrons; Escherichia coli; Free Radicals; Glutamic Acid; Models, Molecular; Protons; Ribonucleotide Reductases; Tyrosine; Water | 2022 |
Triazine-pyridine chemistry for protein labelling on tyrosine.
Topics: Cysteine; Proteome; Pyridines; Triazines; Tyrosine | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Kinetic model for reversible radical transfer in ribonucleotide reductase.
Topics: Cysteine; Escherichia coli; Escherichia coli Proteins; Models, Chemical; Molecular Dynamics Simulation; Ribonucleotide Reductases; Thermodynamics; Tyrosine | 2022 |
Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies.
Topics: Animals; Catalytic Domain; Cisplatin; Cysteine; ErbB Receptors; Mice; Mice, Knockout; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Tyrosine | 2022 |
Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress.
Topics: Aspartic Acid; Beta vulgaris; Chlorides; Citric Acid; Cysteine; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glucose; Hot Temperature; Mannitol; Metabolic Networks and Pathways; Plant Roots; Proline; Salinity; Salts; Sodium Chloride; Stress, Physiological; Sugars; Tryptophan; Tyrosine | 2022 |
The cysteine residue in beta-lactoglobulin reacts with oxidized tyrosine residues in beta-casein to give casein-lactoglobulin dimers.
Topics: Caseins; Cysteine; Lactoglobulins; Tyrosine; Ubiquitins | 2023 |
Residue-Selective C-H Sulfenylation Enabled by Acid-Activated S-Acetamidomethyl Cysteine Sulfoxide with Application to One-Pot Stapling and Lipidation Sequence.
Topics: Cysteine; Guanidine; Peptides; Sulfoxides; Tyrosine | 2023 |
Standardized ileal digestibility of amino acids in cottonseed meal fed to pregnant and non-pregnant sows.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Cottonseed Oil; Cysteine; Diet; Digestion; Female; Glycine max; Ileum; Methionine; Pregnancy; Serine; Swine; Threonine; Tyrosine | 2023 |
Tyrosinase-Catalyzed Peptide Macrocyclization for mRNA Display.
Topics: Catalysis; Cyclization; Cysteine; Ligands; Monophenol Monooxygenase; Peptides; RNA, Messenger; Tyrosine | 2023 |
A Single DNA Point Mutation Leads to the Formation of a Cysteine-Tyrosine Crosslink in the Cysteine Dioxygenase from
Topics: Animals; Bacillus subtilis; Cysteine; Cysteine Dioxygenase; Kinetics; Mice; Point Mutation; Tyrosine | 2023 |