tyrosine has been researched along with cyclin d1 in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (12.00) | 18.2507 |
2000's | 28 (56.00) | 29.6817 |
2010's | 14 (28.00) | 24.3611 |
2020's | 2 (4.00) | 2.80 |
Authors | Studies |
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Rieber, M; Strasberg Rieber, M | 1 |
Carbonaro-Hall, DA; Hall, FL; Harper, JW; Warburton, D; Williams, RT; Wu, F; Wu, L | 1 |
Campbell, DH; Daly, RJ; deFazio, A; Sutherland, RL | 1 |
Mage, RG; Pospisil, R | 1 |
Safe, S; Smith, R; Wang, W | 1 |
Manabe, R; Oh-e, N; Sekiguchi, K | 1 |
Bertics, PJ; Chun, TY; Gorski, J; Kim, YN; Watters, JJ | 1 |
Eghbali-Webb, M; Griffin, M; Lee, HW; Zhao, L | 1 |
Dupont, J; Le Roith, D | 1 |
Kim, K; Lee, KY | 1 |
Danilkovitch-Miagkova, A; Leonard, EJ; Miagkov, A; Nakaigawa, N; Skeel, A; Zbar, B | 1 |
Bijur, GN; Jope, RS | 1 |
Guillemot, L; Levy, A; Raymondjean, M; Rothhut, B | 1 |
Chen, HC; Chuang, LY; Guh, JY; Huang, JS; Hung, WC; Lai, YH | 1 |
Avril, S; Bienvenu, F; Coqueret, O; Gascan, H; Giraud, S; Heery, DM | 1 |
Hammill, AM; Hsueh, RC; Lee, JA; Scheuermann, RH; Uhr, JW | 1 |
Asselin, C; Charland, S; Duchesne, C; Nahmias, C; Rivard, N | 1 |
Burch, P; Heintz, NH; Janssen-Heininger, Y; Schellekens, H; Warner, L; Yuan, Z | 1 |
Gallick, GE; Herynk, MH; Radinsky, R; Tsan, R | 1 |
Fukushima, N; Ishibashi, T; Kondo, M; Nishihira, J; Sato, Y; Sun, B; Suzuki, M; Todo, S | 1 |
Brattain, MG; DeArmond, D; Freeman, JW; Jessup, JM; Kreisberg, J; Malik, S; Zhao, S | 1 |
Pai, R; Tarnawski, AS; Tran, T | 1 |
Feng, H; Kita, Y; Kitanaka, A; Kuriyama, S; Kurokohchi, K; Masaki, T; Uchida, N; Watanabe, S; Yoshida, S; Yoshiji, H; Yuji, J | 1 |
Cordes, N | 1 |
Chen, A; Xu, J | 1 |
Obikane, Y | 1 |
Debidda, M; Poli, V; Wang, L; Zang, H; Zheng, Y | 1 |
Chang, TT; Cheng, JJ; Huang, NK; Lu, MK; Wang, DL | 1 |
Wang, MH; Xu, XM; Zhou, YQ | 1 |
Joung, YH; Kim, SY; Lee, KJ; Lee, MY; Lim, EJ; Moon, WK; Park, DK; Park, EU; Park, JH; Park, T; Yang, YM; Ye, SK; Zhang, Z | 1 |
Debnam, ES; Kuhnle, GG; Lee, SY; Munerol, B; Pannala, AS; Pollard, S; Rice-Evans, C; Spencer, JP; Youdim, KA | 1 |
Chen, HC; Chen, SC; Chuang, LY; Guh, JY; Huang, JS; Yang, YL | 1 |
Albi, E; Rossi, G; Viola Magni, M | 1 |
Shields, BJ; Tiganis, T | 1 |
Agarwal, S; Liu, J | 1 |
Bu, G; Hu, K; Lin, L; Mars, WM; Reeves, WB; Tanaka, S | 1 |
Chen, S; Hu, K; Lin, N; Pan, W; Xu, L; Xu, R | 1 |
Cho, T; Fernandez, M; Hatakeyama, M; Karisch, R; Kikuchi, I; Meyerson, M; Neel, BG; Obuse, C; Ohnishi, N; Rozenblatt-Rosen, O; Saito, Y; Seidi, A; Takahashi, A; Tsutsumi, R | 1 |
Chen, Y; Choong, LY; Lim, SK; Lim, YP; Loh, MC; Salto-Tellez, M; Shah, N; Toy, W; Wong, CY | 1 |
Kokkoli, E; Pearce, TR; Shroff, K | 1 |
Abbondanza, C; Auricchio, F; Barone, MV; Castoria, G; de Falco, A; De Rosa, C; Giovannelli, P; Giraldi, T; Lombardi, M; Migliaccio, A | 1 |
Chen, YK; Guan, F; Lee, MJ; Li, G; Lin, Y; Liu, AB; Shih, W; Yang, CS; Yang, Z | 1 |
Blain, SW; Ciznadija, D; Hukkelhoven, E; Koff, A; Liu, Y; Yeh, N | 1 |
Cao, Z; Chen, J; Gao, J; Huang, C; Huang, H; Li, J; Zhang, D; Zhang, J; Zhang, R | 1 |
Abu Aboud, O; Weiss, RH; Wettersten, HI | 1 |
Cao, R; Dan, HC; Jiang, W; Ju, L; Qian, G; Wang, G; Wang, X; Wang, Y; Wu, M; Xiao, Y | 1 |
Chakrabandhu, K; Huault, S; Hueber, AO; Ta, NL | 1 |
Hori, T; Moriyama, K | 1 |
Dong, L; Guo, HY; Huang, XX; Huang, YQ; Jiang, XM; Liu, TT; Shen, XZ; Shi, X; Song, GQ; Weng, SQ; Yu, XN; Zhang, GC; Zhu, HR; Zhu, JM | 1 |
Liu, J; Wang, J; Xu, Y; Yan, X; Zhang, R; Zhao, J | 1 |
1 review(s) available for tyrosine and cyclin d1
Article | Year |
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Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects.
Topics: Breast Neoplasms; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Estradiol; Female; Humans; Insulin-Like Growth Factor I; Microfilament Proteins; Mitogen-Activated Protein Kinases; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptor, IGF Type 1; Retinoblastoma Protein; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2001 |
49 other study(ies) available for tyrosine and cyclin d1
Article | Year |
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Suppression of cyclin D1 but not cdk4 or cyclin A with induction of melanoma terminal differentiation.
Topics: Animals; Biomarkers, Tumor; Cell Cycle; Cell Differentiation; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oncogene Proteins; Proto-Oncogene Proteins; S Phase; Tyrosine; Vanadates | 1995 |
Two potentially oncogenic cyclins, cyclin A and cyclin D1, share common properties of subunit configuration, tyrosine phosphorylation and physical association with the Rb protein.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cells, Cultured; Cyclin D1; Cyclins; Humans; Molecular Sequence Data; Oncogene Proteins; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogenes; Recombinant Proteins; Retinoblastoma Protein; Tumor Cells, Cultured; Tyrosine | 1993 |
Expression and tyrosine phosphorylation of EMS1 in human breast cancer cell lines.
Topics: Breast Neoplasms; Cortactin; Cyclin D1; Cyclins; Female; Gene Amplification; Humans; Microfilament Proteins; Neoplasm Proteins; Oncogene Proteins; Phosphorylation; RNA, Messenger; Tumor Cells, Cultured; Tyrosine | 1996 |
B-cell superantigens may play a role in B-cell development and selection in the young rabbit appendix.
Topics: Amino Acid Sequence; Animals; Apoptosis; Appendix; B-Lymphocyte Subsets; bcl-X Protein; Cell Differentiation; Cell Separation; Cell Survival; Cyclin D1; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Lymphocyte Activation; Molecular Sequence Data; Mutation; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rabbits; Superantigens; Tyrosine | 1998 |
Aryl hydrocarbon receptor-mediated antiestrogenicity in MCF-7 cells: modulation of hormone-induced cell cycle enzymes.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; cdc25 Phosphatases; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cyclins; Estradiol; Estrogen Antagonists; Female; Humans; Microtubule-Associated Proteins; Phosphorylation; Polychlorinated Dibenzodioxins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptors, Aryl Hydrocarbon; Retinoblastoma Protein; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Tyrosine | 1998 |
Alternatively spliced EDA segment regulates fibronectin-dependent cell cycle progression and mitogenic signal transduction.
Topics: Alternative Splicing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; CHO Cells; Cricetinae; Crk-Associated Substrate Protein; Cyclin D1; Enzyme Activation; Fibronectins; Mitogen-Activated Protein Kinase 1; Mitogens; Phosphoproteins; Phosphorylation; Protein Binding; Proteins; Receptors, Fibronectin; Retinoblastoma Protein; Retinoblastoma-Like Protein p130; Signal Transduction; Tyrosine; Up-Regulation | 1999 |
Estrogen modulation of prolactin gene expression requires an intact mitogen-activated protein kinase signal transduction pathway in cultured rat pituitary cells.
Topics: Animals; Benzoquinones; Butadienes; Cells, Cultured; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrogens; Female; Flavonoids; Gene Expression Regulation; Lactams, Macrocyclic; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Pituitary Gland; Prolactin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Pyrazoles; Pyrimidines; Quinones; Rats; Rats, Inbred F344; Rifabutin; RNA, Messenger; Signal Transduction; src-Family Kinases; Steroids; Transcription, Genetic; Tyrosine | 2000 |
Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen.
Topics: Age Factors; Animals; Blotting, Western; Cell Division; Cell Nucleus; Cells, Cultured; Cyclin B; Cyclin B1; Cyclin D1; Cytoplasm; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Female; Fibroblasts; Fulvestrant; Genistein; Hypoxia; Male; Myocardium; Phosphorylation; Precipitin Tests; Proliferating Cell Nuclear Antigen; Protein Binding; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Receptors, Estrogen; Response Elements; Sex Factors; Tyrosine | 2000 |
Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function.
Topics: 3T3 Cells; Animals; beta Catenin; Biological Transport; Cell Communication; Cell Membrane; Colonic Neoplasms; Cyclin D1; Cytoplasm; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Humans; Luciferases; Lymphoid Enhancer-Binding Factor 1; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway.
Topics: 3T3 Cells; Animals; Axin Protein; beta Catenin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Transformation, Neoplastic; Cyclin D1; Cytoskeletal Proteins; Dogs; Glycogen Synthase Kinase 3; Mice; Mutagenesis, Site-Directed; Phosphorylation; Proteins; Proto-Oncogene Proteins c-met; Proto-Oncogene Proteins c-myc; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Repressor Proteins; Signal Transduction; TCF Transcription Factors; Trans-Activators; Transcription Factor 7-Like 2 Protein; Transcription Factors; Transcriptional Activation; Tyrosine | 2001 |
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta.
Topics: Apoptosis Inducing Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclin D1; Enzyme Inhibitors; Flavoproteins; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Hot Temperature; Humans; Lithium; Membrane Proteins; Phosphorylation; Serine; Staurosporine; Tumor Cells, Cultured; Tyrosine | 2001 |
Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT(1A) cells.
Topics: Androstadienes; Angiotensin II; Animals; Binding Sites; Butadienes; Cell Line; Cell Nucleus; CHO Cells; Cricetinae; Cyclin D1; DNA Mutational Analysis; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Genes, Dominant; Humans; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mutagenesis, Site-Directed; Nitriles; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Transcription Factors; Transcriptional Activation; Transfection; Tyrosine; Up-Regulation; Wortmannin | 2001 |
Advanced glycation end product-induced proliferation in NRK-49F cells is dependent on the JAK2/STAT5 pathway and cyclin D1.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Glycation End Products, Advanced; Janus Kinase 2; Milk Proteins; Oligonucleotides; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; STAT5 Transcription Factor; Time Factors; Trans-Activators; Tyrosine | 2001 |
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a.
Topics: Base Sequence; Blotting, Western; Cell Nucleus; Chromatin; Cyclin D1; Dimerization; DNA-Binding Proteins; DNA, Complementary; Glutathione Transferase; Histone Acetyltransferases; Histones; Humans; Immunoblotting; Interleukin-6; Luciferases; Molecular Sequence Data; Nuclear Receptor Coactivator 1; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tyrosine | 2002 |
Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.
Topics: Amino Acid Substitution; Animals; Apoptosis; B-Lymphocyte Subsets; B-Lymphocytes; Cell Division; Cell Line, Tumor; Cell Survival; Cyclin D1; Enzyme Activation; Enzyme Precursors; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Lymphoma, B-Cell; Mice; Mutation; Phenylalanine; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; Syk Kinase; Tyrosine | 2002 |
Negative regulation of beta-catenin signaling by tyrosine phosphatase SHP-1 in intestinal epithelial cells.
Topics: Animals; beta Catenin; Binding Sites; Blotting, Western; Caco-2 Cells; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; Cyclin D1; Cytoskeletal Proteins; Epithelial Cells; Fluorescent Antibody Technique, Indirect; G1 Phase; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Humans; Immunoblotting; Intestinal Mucosa; Intestines; Intracellular Signaling Peptides and Proteins; Luciferases; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Mutation; Phosphorylation; Precipitin Tests; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-fos; Rats; Resting Phase, Cell Cycle; S Phase; Signal Transduction; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Tyrosine | 2003 |
Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide.
Topics: Animals; Catalase; Cell Cycle; Cells, Cultured; Cyclin D1; Epithelial Cells; Fluoresceins; Gene Expression Regulation; Hydrogen Peroxide; Mice; Molsidomine; Nitric Oxide Donors; Nitrogen Dioxide; Oxidants; Pulmonary Alveoli; Signal Transduction; Superoxide Dismutase; Transcription Factor AP-1; Tyrosine | 2003 |
Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin.
Topics: beta Catenin; Blotting, Western; Cell Adhesion; Cell Movement; Colony-Forming Units Assay; Colorectal Neoplasms; Cyclin D1; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Luciferases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-met; Trans-Activators; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine | 2003 |
Induction of macrophage migration inhibitory factor by lysophosphatidic acid: relevance to tumor growth and angiogenesis.
Topics: Animals; Cell Division; Cell Line, Tumor; Cyclin D1; DNA; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Immunoblotting; Lysophospholipids; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Phosphorylation; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Double-Stranded; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Tyrosine; Up-Regulation; Vascular Endothelial Growth Factor A | 2003 |
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
Topics: CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; DNA-Binding Proteins; ErbB Receptors; Growth Substances; Humans; Pancreatic Neoplasms; Phosphorylation; Receptor, ErbB-2; Retinoblastoma Protein; STAT3 Transcription Factor; Trans-Activators; Tumor Suppressor Proteins; Tyrosine | 2003 |
Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness.
Topics: beta Catenin; Biological Assay; Cadherins; Cell Line; Colonic Neoplasms; Cyclin D1; Cytoskeletal Proteins; Deoxycholic Acid; Gene Expression Regulation; Humans; Neoplasm Invasiveness; Phosphorylation; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Small Interfering; Signal Transduction; Trans-Activators; Tyrosine; Urokinase-Type Plasminogen Activator | 2004 |
Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; CDC2 Protein Kinase; Cell Division; Cell Fractionation; Cell Nucleus; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cytosol; Hepatectomy; Hepatocytes; Immunohistochemistry; Liver Regeneration; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Rats; Rats, Wistar; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine | 2004 |
Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity.
Topics: Actins; Cell Line, Tumor; Cyclin D1; Cytoskeletal Proteins; Extracellular Matrix Proteins; Focal Adhesions; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Integrin beta1; Lung Neoplasms; MAP Kinase Signaling System; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Retinoblastoma Protein; Subcellular Fractions; Transfection; Tyrosine | 2004 |
Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.
Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Curcumin; Cyclin D1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Phosphorylation; Plasmids; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transfection; Tyrosine | 2005 |
[The role of macrophage migration inhibitory factor (MIF) in cell proliferation signal transmission].
Topics: 3T3 Cells; Adenoviridae; Animals; Antisense Elements (Genetics); Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin D1; Flow Cytometry; Genetic Vectors; Macrophage Migration-Inhibitory Factors; Mice; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tyrosine | 2004 |
A role of STAT3 in Rho GTPase-regulated cell migration and proliferation.
Topics: Actins; Active Transport, Cell Nucleus; Animals; cdc42 GTP-Binding Protein; Cell Movement; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cyclin D1; Cytoskeleton; DNA-Binding Proteins; DNA, Complementary; Fibroblasts; Gene Deletion; Genes, Reporter; Immunoblotting; Inflammation; Interleukin-6; Luciferases; Mice; Mice, Knockout; Microscopy, Fluorescence; Models, Biological; Mutation; Myosin Light Chains; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Structure, Tertiary; rac1 GTP-Binding Protein; Retroviridae; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Serine; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Wound Healing | 2005 |
Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Cattle; Cells, Cultured; Chemical Fractionation; Cyclin D1; Dose-Response Relationship, Drug; Endothelium, Vascular; Medicine, East Asian Traditional; Phosphorylation; Plant Extracts; Polyporales; Polysaccharides; Promoter Regions, Genetic; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2005 |
Mechanisms of cytoplasmic {beta}-catenin accumulation and its involvement in tumorigenic activities mediated by oncogenic splicing variant of the receptor originated from Nantes tyrosine kinase.
Topics: Active Transport, Cell Nucleus; Alternative Splicing; Androstadienes; Animals; beta Catenin; Blotting, Western; Cell Nucleus; Cyclin D1; Cytoplasm; Cytoskeletal Proteins; Enzyme Inhibitors; Gene Silencing; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Models, Biological; Neoplasms; NIH 3T3 Cells; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myc; Receptor Protein-Tyrosine Kinases; RNA, Messenger; RNA, Small Interfering; Serine; Trans-Activators; Tyrosine; Wortmannin | 2005 |
Hypoxia activates the cyclin D1 promoter via the Jak2/STAT5b pathway in breast cancer cells.
Topics: Anaerobiosis; Animals; Breast Neoplasms; Cell Hypoxia; Chlorocebus aethiops; COS Cells; Cyclin D1; Deferoxamine; Female; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 2; Phosphorylation; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Serine; Tumor Cells, Cultured; Tyrosine | 2005 |
The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth.
Topics: Absorption; Animals; Apoptosis; Caco-2 Cells; Caspase 3; Caspases; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Gastrointestinal Tract; Humans; In Vitro Techniques; Mitogen-Activated Protein Kinase Kinases; Nitrosamines; Nitroso Compounds; Nitrous Acid; Phenols; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Nitrogen Species; Time Factors; Tyrosine | 2006 |
Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells.
Topics: Animals; Cell Line; Cyclin D1; Cyclin E; Fibroblasts; Glycation End Products, Advanced; HSP72 Heat-Shock Proteins; Janus Kinase 2; Kidney; Mitosis; Phosphorylation; Protein Interaction Mapping; Rats; Reactive Oxygen Species; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Transcription Factors; Tyrosine | 2007 |
Signal transducer and activator of transcription 3 and sphingomyelin metabolism in intranuclear complex during cell proliferation.
Topics: Animals; Cell Proliferation; Cyclin D; Cyclin D1; Cyclins; Female; Lipid Metabolism; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase; STAT3 Transcription Factor; Time Factors; Tyrosine | 2007 |
Replication checkpoint control by a PTK/STAT3/cyclin D1 axis.
Topics: Cell Cycle; Cyclin D1; DNA Replication; Humans; Phosphorylation; Protein-Tyrosine Kinases; S Phase; STAT3 Transcription Factor; Tyrosine | 2009 |
Mechanical signals activate vascular endothelial growth factor receptor-2 to upregulate endothelial cell proliferation during inflammation.
Topics: Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclin D1; Endothelial Cells; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Inflammation; Interleukin-1beta; Phosphorylation; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stress, Mechanical; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway.
Topics: Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Cyclin D1; Embryo, Mammalian; Female; Fibroblasts; Fluorescent Antibody Technique; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoenzyme Techniques; Immunoprecipitation; Kidney; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice; Mice, Knockout; Mitosis; Mutagenesis, Site-Directed; Phosphorylation; Rats; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tissue Plasminogen Activator; Tyrosine | 2010 |
NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats.
Topics: Actins; Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Hepatic Stellate Cells; Indoles; Liver; Liver Cirrhosis, Experimental; Male; MAP Kinase Kinase 1; Phosphorylation; Propionates; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Time Factors; Transfection; Tyrosine | 2011 |
SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.
Topics: Animals; beta Catenin; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyclin D1; Gene Expression Regulation; HEK293 Cells; Humans; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-myc; Signal Transduction; Tumor Suppressor Proteins; Tyrosine; Wnt Proteins | 2011 |
Elevated NRD1 metalloprotease expression plays a role in breast cancer growth and proliferation.
Topics: Apoptosis; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Disease Progression; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunohistochemistry; Metalloproteases; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tyrosine; Up-Regulation | 2011 |
Enhanced integrin mediated signaling and cell cycle progression on fibronectin mimetic peptide amphiphile monolayers.
Topics: Amino Acid Sequence; Biomimetic Materials; Biomimetics; Cell Cycle; Cyclin D1; Fibronectins; Focal Adhesion Protein-Tyrosine Kinases; Human Umbilical Vein Endothelial Cells; Humans; Integrin alpha5beta1; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Peptides; Phosphorylation; Serum Albumin, Bovine; Signal Transduction; Tyrosine | 2012 |
Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells.
Topics: Active Transport, Cell Nucleus; Animals; Breast Neoplasms; Cell Cycle Checkpoints; Cell Growth Processes; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyclin D1; Cytoplasm; Estradiol; Estrogen Receptor alpha; Exportin 1 Protein; Female; Forkhead Transcription Factors; Humans; Karyopherins; MCF-7 Cells; Mice; Mutation; NIH 3T3 Cells; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; S Phase; src-Family Kinases; Transcription, Genetic; Tyrosine | 2012 |
δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats.
Topics: Aldehydes; alpha-Tocopherol; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Cyclin D1; Dinoprost; Dinoprostone; gamma-Tocopherol; Immunohistochemistry; Male; Models, Chemical; Rats; Rats, Inbred F344; Tocopherols; Tyrosine | 2012 |
Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma.
Topics: Amino Acid Sequence; Animals; Cell Proliferation; Central Nervous System Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; HEK293 Cells; Humans; Mice; Molecular Sequence Data; Mutation; Phosphorylation; Tyrosine | 2012 |
X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis.
Topics: Binding Sites; Blotting, Western; Cell Adhesion; Cell Proliferation; Colonic Neoplasms; Cyclin D1; G1 Phase; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mutation; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; S Phase; Transcription Factor AP-1; Tyrosine; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein | 2013 |
Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells.
Topics: Apoptosis; Carcinoma, Renal Cell; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase 4; Deoxyglucose; G1 Phase; Glucose; Glycolysis; Humans; Immunoblotting; Immunohistochemistry; Kidney Neoplasms; Oxazoles; PPAR alpha; Proto-Oncogene Proteins c-myc; Resting Phase, Cell Cycle; RNA Interference; Tyrosine | 2013 |
Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway.
Topics: Anilides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Enzyme Activation; Epithelial-Mesenchymal Transition; ErbB Receptors; G1 Phase Cell Cycle Checkpoints; Glycogen Synthase Kinase 3 beta; Humans; Neoplasm Invasiveness; Oxazoles; PPAR gamma; Proto-Oncogene Proteins c-akt; Simvastatin; Tyrosine; Urinary Bladder; Urinary Bladder Neoplasms | 2016 |
The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Epidermal Growth Factor; ErbB Receptors; fas Receptor; HCT116 Cells; Humans; Neoplasm Recurrence, Local; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Tyrosine | 2018 |
BCR-ABL induces tyrosine phosphorylation of YAP leading to expression of Survivin and Cyclin D1 in chronic myeloid leukemia cells.
Topics: Adaptor Proteins, Signal Transducing; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Fusion Proteins, bcr-abl; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phosphorylation; Protein Kinase Inhibitors; src-Family Kinases; Survivin; Transcription Factors; Tyrosine; YAP-Signaling Proteins | 2019 |
Upregulated calcium-binding tyrosine phosphorylation-regulated protein-a/b regulates cell proliferation and apoptosis and predicts poor prognosis in hepatocellular carcinoma.
Topics: Aged; Alternative Splicing; Apoptosis; Biomarkers, Tumor; Calcium; Calcium-Binding Proteins; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 4; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Middle Aged; Phosphorylation; Prognosis; Protein Binding; Protein Isoforms; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Treatment Outcome; Tyrosine | 2020 |
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1B Inhibition Promotes Megakaryocyte Polyploidization and Platelet Production.
Topics: Animals; Blood Platelets; Cyclin D1; Megakaryocytes; Mice; Phosphorylation; Thrombocytopenia; Tyrosine | 2023 |