tyrosine and colchicine

tyrosine has been researched along with colchicine in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199016 (35.56)18.7374
1990's12 (26.67)18.2507
2000's14 (31.11)29.6817
2010's0 (0.00)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Shimizu, T; Shishiba, Y1
Deanin, GG; Gordon, MW; Thompson, WC1
Nath, J; Ray, P; Strott, CA1
Forrest, GL; Klevecz, RR1
Flavin, M; Nath, J1
Flavin, M; Raybin, D1
Arce, CA; Barra, HS; Caputo, R; Rodriguez, JA1
Arce, CA; Barra, HS1
Hu, F1
Arce, CA; Barra, HS; Caputto, R; Rodríguez, JA1
Hermand, E; Léonardelli, J; Tramu, G1
Silagi, S1
Flavin, M; Kumar, N1
Flavin, M; Nath, J; Schiffmann, E1
Mikulíková, D; Trnavský, K1
Keast, JR; Manley, SW; Yap, AS1
Bergeron, JJ; Bevan, AP; Burgess, JW; Drake, PG; Posner, BI; Shaver, A1
de Médicis, R; Gaudry, M; Lussier, A; Naccache, PH; Poubelle, PE; Roberge, CJ1
Modig, C; Strömberg, E; Wallin, M1
Rozengurt, E; Sinnett-Smith, J; Valverde, AM; Zachary, I1
Malawista, SE; Smallwood, JI1
de Médicis, R; Gaudry, M; Gilbert, C; Lussier, A; Malawista, SE; Naccache, PH; Poubelle, PE; Roberge, CJ1
Madianos, PN; Papapanou, PN; Sandros, J1
Dougherty, SF; Falk, LA; Pluznik, DH; Rao, P; Sawada, T1
Skoufias, DA; Wilson, L1
Abedi, H; Zachary, I1
Shea, TB1
Ali, S; Deng, H; Dong, K; Giebisch, G; Gu, R; Hebert, SC; Huang, XY; Moral, Z; Sterling, H; Wang, WH; Wei, Y1
Correa, LM; Miller, MG1
Kucik, DF; Li, J; Zhou, X1
Bertics, PJ; Dam, P; Kim, YN1
Nick, P; Wang, QY; Wiesler, B1
GALBRAITH, DB1
Faisal, A; Kleiner, S; Nagamine, Y1
Akhtar, N; Bagley, S; Gilmore, AP; Lowe, ET; Streuli, CH; Valentijn, A; Zoubiane, GS1
Arai, M; Koizumi, Y; Omura, S; Tomoda, H1
Chen, Z; Kovar, P; Lin, NH; Merta, PJ; Sham, HL; Tahir, SK; Zhang, H1
Inal, J; Miot, S; Schifferli, JA1
Anderson, CR; Gapud, EJ; Hamel, E; Jung, MK; Knight, JC; Pettit, GR; Pettit, RK1
Caperta, AD; Delgado, M; Houben, A; Jones, RN; Meister, A; Ressurreição, F; Viegas, W1
Lopez-Perez, M; Salazar, EP1
Chien, S; Haga, JH; Hu, YL; Li, YS; Miao, H; Wang, Y1
Bedi, K; Caporizzo, MA; Chen, CY; Margulies, KB; Prosser, BL1
Lau, W; Nett, RS; Sattely, ES1
Bodakuntla, S; Chandra, A; Das, R; Janke, C; Jijumon, AS; Kesarwani, S; Lama, P; Rao, BM; Reddy, PP; Sirajuddin, M1

Reviews

1 review(s) available for tyrosine and colchicine

ArticleYear
Colchicine, crystals, and neutrophil tyrosine phosphorylation.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Colchicine; Gout; Humans; Neutrophils; Phosphorylation; Tyrosine

1993

Other Studies

44 other study(ies) available for tyrosine and colchicine

ArticleYear
Effect of triiodothyronine or iodide on the thyroidal secretion in vitro: Inhibition of TSH- and dibutyryl-cyclic-AMP induced endocytosis.
    Endocrinologia japonica, 1975, Volume: 22, Issue:1

    Topics: Animals; Bucladesine; Colchicine; Colloids; Cyclic AMP; Endocytosis; In Vitro Techniques; Iodides; Male; Mice; Thyroid Gland; Thyrotropin; Triiodothyronine; Tyrosine

1975
Intact microtubules are required for rapid turnover of carboxyl-terminal tyrosine of alpha-tubulin in cell cultures.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:3

    Topics: Animals; Cells, Cultured; Chick Embryo; Colchicine; Glycoproteins; Kinetics; Microtubules; Muscles; Podophyllotoxin; Pressure; Tubulin; Tyrosine; Vinblastine

1979
Purification of bovine adrenocortical and brain tubulin. A comparative study.
    Biochimica et biophysica acta, 1979, Nov-23, Volume: 581, Issue:1

    Topics: Adrenal Cortex; Amino Acids; Animals; Brain; Brain Chemistry; Cattle; Colchicine; Molecular Weight; Organ Specificity; Protein Binding; Tubulin; Tyrosine

1979
Tyrosyltubulin ligase and colchicine binding activity in synchronized Chinese hamster cells.
    The Journal of cell biology, 1978, Volume: 78, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Cycle; Cell Division; Cell Line; Colchicine; Cricetinae; Cricetulus; DNA; Glycoproteins; Magnesium; Peptide Synthases; Potassium; Protein Binding; Tubulin; Tyrosine

1978
A structural difference between cytoplasmic and membrane-bound tubulin of brain.
    FEBS letters, 1978, Nov-15, Volume: 95, Issue:2

    Topics: Animals; Brain Chemistry; Carboxypeptidases; Cell Membrane; Colchicine; Cytoplasm; Glycoproteins; Protein Binding; Tubulin; Tyrosine; Vinblastine

1978
An enzyme tyrosylating alpha-tubulin and its role in microtubule assembly.
    Biochemical and biophysical research communications, 1975, Aug-04, Volume: 65, Issue:3

    Topics: Aging; Animals; Brain; Cattle; Colchicine; Kinetics; Ligases; Microtubules; Nerve Tissue Proteins; Rats; Receptors, Drug; Species Specificity; Time Factors; Tubulin; Tyrosine

1975
Incorporation of L-tyrosine, L-phenylalanine and L-3,4-dihydroxyphenylalanine as single units into rat brain tubulin.
    European journal of biochemistry, 1975, Nov-01, Volume: 59, Issue:1

    Topics: Animals; Brain; Colchicine; Dihydroxyphenylalanine; Glycoproteins; Phenylalanine; Rats; Receptors, Drug; Tubulin; Tyrosine

1975
Release of C-terminal tyrosine from tubulin and microtubules at steady state.
    The Biochemical journal, 1985, Feb-15, Volume: 226, Issue:1

    Topics: Animals; Carboxypeptidases; Colchicine; In Vitro Techniques; Macromolecular Substances; Microtubule Proteins; Microtubules; Rats; Tubulin; Tyrosine

1985
The influence of certain hormones and chemicals on mammalian pigment cells.
    The Journal of investigative dermatology, 1966, Volume: 46, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Chromatophores; Colchicine; Copper; Culture Techniques; Dihydroxyphenylalanine; Hydroquinones; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Melatonin; Mice; Motion Pictures; Pigmentation; Tyrosine

1966
Some common properties of the protein that incorporates tyrosine as a single unit and the microtubule proteins.
    Biochemical and biophysical research communications, 1974, Oct-23, Volume: 60, Issue:4

    Topics: Animals; Binding Sites; Brain; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Colchicine; Electrophoresis, Polyacrylamide Gel; Macromolecular Substances; Microtubules; Molecular Weight; Nerve Tissue Proteins; Protein Binding; Rats; Tritium; Tyrosine; Vinblastine

1974
[Effect of sulpiride on the hypothalamic neurons producing LH-RH].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1973, Volume: 167, Issue:12

    Topics: Animals; Castration; Colchicine; Female; Gonadotropin-Releasing Hormone; Guinea Pigs; Hypothalamus; Injections, Intraperitoneal; Male; Microscopy, Fluorescence; Neurons; Sulpiride; Testis; Time Factors; Tyrosine

1973
Control of pigment production in mouse melanoma cells in vitro. Evocation and maintenance.
    The Journal of cell biology, 1969, Volume: 43, Issue:2

    Topics: Animals; Antimetabolites; Autoradiography; Catechol Oxidase; Cell Differentiation; Cell Division; Cell Line; Chromosomes; Clone Cells; Colchicine; Culture Media; Cytarabine; Melanins; Melanoma; Mice; Models, Biological; Pigmentation; Time Factors; Tyrosine

1969
Preferential action of a brain detyrosinolating carboxypeptidase on polymerized tubulin.
    The Journal of biological chemistry, 1981, Jul-25, Volume: 256, Issue:14

    Topics: Animals; Antineoplastic Agents, Phytogenic; Brain; Calcium Chloride; Carbon Radioisotopes; Carboxypeptidases; Cattle; Colchicine; Kinetics; Paclitaxel; Substrate Specificity; Terpenes; Tubulin; Tyrosine; Vinblastine

1981
Stimulation of tubulin tyrosinolation in rabbit leukocytes evoked by the chemoattractant formyl-methionyl-leucyl-phenylalanine.
    The Journal of cell biology, 1981, Volume: 91, Issue:1

    Topics: Alkaloids; Animals; Chemotaxis, Leukocyte; Colchicine; Leukocytes; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Paclitaxel; Peptide Synthases; Protein Binding; Rabbits; Tubulin; Tyrosine

1981
[Colchicine derivatives and their effect on lysosomal enzyme release from polymorphonuclear leukocytes and on intracellular levels of 3',5'cyclic adenosine monophosphate following urate crystal phagocytosis (author's transl)].
    Casopis lekaru ceskych, 1980, Dec-19, Volume: 119, Issue:51

    Topics: Colchicine; Cyclic AMP; Glucuronidase; Humans; L-Lactate Dehydrogenase; Lysosomes; Neutrophils; Phagocytosis; Tyrosine; Uric Acid

1980
Thyroid cell spreading and focal adhesion formation depend upon protein tyrosine phosphorylation and actin microfilaments.
    Experimental cell research, 1994, Volume: 210, Issue:2

    Topics: Actin Cytoskeleton; Actins; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Colchicine; Cytochalasin B; Fluorescent Antibody Technique; Genistein; Heparin; Isoflavones; Kinetics; Phosphotyrosine; Protein-Tyrosine Kinases; Swine; Thyroid Gland; Tyrosine; Vinculin

1994
Selective activation of the rat hepatic endosomal insulin receptor kinase. Role for the endosome in insulin signaling.
    The Journal of biological chemistry, 1995, May-05, Volume: 270, Issue:18

    Topics: Animals; Blood Glucose; Colchicine; Diaphragm; Endocytosis; Endosomes; Enzyme Activation; Insulin; Liver; Organometallic Compounds; Phenanthrolines; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Time Factors; Tumor Cells, Cultured; Tyrosine

1995
Crystal-induced neutrophil activation. IV. Specific inhibition of tyrosine phosphorylation by colchicine.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Blood Proteins; Calcium Pyrophosphate; Colchicine; Crystallization; Demecolcine; Humans; In Vitro Techniques; Indomethacin; Kinetics; Neutrophils; Nocodazole; Phenylbutazone; Phosphorylation; Phosphotyrosine; Tyrosine; Uric Acid; Vinblastine

1993
Different stability of posttranslationally modified brain microtubules isolated from cold-temperate fish.
    Molecular and cellular biochemistry, 1994, Jan-26, Volume: 130, Issue:2

    Topics: Acetylation; Animals; Colchicine; Cold Climate; Fishes; Microtubule-Associated Proteins; Oncorhynchus mykiss; Protein Processing, Post-Translational; Species Specificity; Tyrosine

1994
Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Cytoskeleton; Diglycerides; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Indoles; Intracellular Signaling Peptides and Proteins; Kinetics; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Terpenes; Thapsigargin; Tyrosine

1993
Paradoxical effects of colchicine on the activation of human neutrophilis by chemotactic factors and inflammatory microcrystal.
    Journal of leukocyte biology, 1996, Volume: 59, Issue:6

    Topics: Adult; Calcium Pyrophosphate; Colchicine; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophil Activation; Neutrophils; Paclitaxel; Phosphorylation; Tyrosine; Uric Acid

1996
Cellular events concurrent with Porphyromonas gingivalis invasion of oral epithelium in vitro.
    European journal of oral sciences, 1996, Volume: 104, Issue:4 ( Pt 1)

    Topics: Cadaverine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Coated Pits, Cell-Membrane; Colchicine; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Epithelium; Genistein; Humans; Isoflavones; KB Cells; Microtubules; Nasopharynx; Nocodazole; Ouabain; Phosphorylation; Porphyromonas gingivalis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction; Staurosporine; Tyrosine

1996
Colchicine down-regulates lipopolysaccharide-induced granulocyte-macrophage colony-stimulating factor production in murine macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Oct-01, Volume: 159, Issue:7

    Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; Colchicine; Down-Regulation; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Lipopolysaccharides; Macrophages; Mice; Microtubules; NF-kappa B; Paclitaxel; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Time Factors; Transcription, Genetic; Tubulin; Tyrosine

1997
Assembly and colchicine binding characteristics of tubulin with maximally tyrosinated and detyrosinated alpha-tubulins.
    Archives of biochemistry and biophysics, 1998, Mar-01, Volume: 351, Issue:1

    Topics: Animals; Carboxypeptidases; Carboxypeptidases A; Cattle; Colchicine; Dimerization; Kinetics; Peptide Synthases; Thermodynamics; Tubulin; Tyrosine

1998
Cytochalasin D stimulation of tyrosine phosphorylation and phosphotyrosine-associated kinase activity in vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1998, Apr-28, Volume: 245, Issue:3

    Topics: Actins; Animals; Cells, Cultured; Colchicine; Cortactin; Cytochalasin D; Microfilament Proteins; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Protein Kinases; Rabbits; Tyrosine

1998
Selective stabilization of microtubules within the proximal region of developing axonal neurites.
    Brain research bulletin, 1999, Volume: 48, Issue:3

    Topics: Acetylation; Animals; Antineoplastic Agents, Phytogenic; Axons; Cell Differentiation; Colchicine; Microscopy, Immunoelectron; Microtubules; Neurites; Neuroblastoma; Neurons; Paclitaxel; Tubulin; Tumor Cells, Cultured; Tyrosine

1999
Regulation of ROMK1 channels by protein-tyrosine kinase and -tyrosine phosphatase.
    The Journal of biological chemistry, 2001, Mar-09, Volume: 276, Issue:10

    Topics: Alanine; Animals; Benzoquinones; Blotting, Western; Colchicine; Concanavalin A; Enzyme Inhibitors; Lactams, Macrocyclic; Microscopy, Fluorescence; Microtubules; Models, Biological; Mutation; Oocytes; Paclitaxel; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Complementary; Sucrose; Time Factors; Tyrosine; Xenopus

2001
Microtubule depolymerization in rat seminiferous epithelium is associated with diminished tyrosination of alpha-tubulin.
    Biology of reproduction, 2001, Volume: 64, Issue:6

    Topics: Acetylation; Animals; Antibody Specificity; Benzimidazoles; Carbamates; Colchicine; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Immunoblotting; Male; Microtubules; Polymers; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Seminiferous Epithelium; Seminiferous Tubules; Solubility; Tubulin; Tyrosine

2001
The microtubule cytoskeleton participates in control of beta2 integrin avidity.
    The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48

    Topics: Animals; Antineoplastic Agents; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Line; Cell Line, Transformed; Colchicine; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Gout Suppressants; Humans; Integrins; Macrophages; Mice; Microscopy, Video; Microtubules; Models, Statistical; Nocodazole; Paclitaxel; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine

2001
Caveolin-1 phosphorylation in human squamous and epidermoid carcinoma cells: dependence on ErbB1 expression and Src activation.
    Experimental cell research, 2002, Oct-15, Volume: 280, Issue:1

    Topics: Androstadienes; Carcinoma, Squamous Cell; Caveolae; Caveolin 1; Caveolins; Cell Line; Chromones; Colchicine; Cyclodextrins; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Humans; Kinetics; Morpholines; Nucleic Acid Synthesis Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; src-Family Kinases; Tumor Cells, Cultured; Tyrosine; Wortmannin

2002
The stability of cortical microtubules depends on their orientation.
    The Plant journal : for cell and molecular biology, 2002, Volume: 32, Issue:6

    Topics: Amino Acid Sequence; Binding Sites; Carbamates; Colchicine; Cotyledon; Dinitrobenzenes; Indoleacetic Acids; Microtubules; Molecular Sequence Data; Phenylcarbamates; Sequence Homology, Amino Acid; Sulfanilamides; Trifluralin; Tubulin; Tyrosine; Urethane; Zea mays

2002
THE AGOUTI PIGMENT PATTERN OF THE MOUSE: A QUANTITATIVE AND EXPERIMENTAL STUDY.
    The Journal of experimental zoology, 1964, Volume: 155

    Topics: Animals; Chromosomes; Colchicine; Dasyproctidae; Dihydroxyphenylalanine; Hair; Mice; Pigmentation; Research; Tyrosine

1964
Non-redundant role of Shc in Erk activation by cytoskeletal reorganization.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Colchicine; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Genes, Reporter; LLC-PK1 Cells; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Models, Biological; Mutation; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Protein Isoforms; Protein Structure, Tertiary; Proteins; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Swine; Transfection; Tyrosine; Up-Regulation; Urokinase-Type Plasminogen Activator

2004
A role for the cytoskeleton in prolactin-dependent mammary epithelial cell differentiation.
    Journal of cell science, 2004, Jan-15, Volume: 117, Issue:Pt 2

    Topics: Animals; Caseins; Cell Differentiation; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; DNA-Binding Proteins; Epithelial Cells; Female; Immunohistochemistry; Integrins; Janus Kinase 2; Mammary Glands, Animal; Mice; Milk Proteins; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Pregnancy; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Prolactin; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Transcription, Genetic; Tyrosine

2004
Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization.
    Biochimica et biophysica acta, 2004, Jul-23, Volume: 1693, Issue:1

    Topics: Animals; Aspergillus; cdc25 Phosphatases; Colchicine; Humans; Hydrogen Peroxide; Imidazoles; Mice; Mitosis; Penicillium; Peptide Fragments; Tritium; Tubulin; Tubulin Modulators; Tyrosine

2004
A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:4

    Topics: Antineoplastic Agents; Binding Sites; Binding, Competitive; Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Separation; Colchicine; Cyclin B; Cyclin B1; Dose-Response Relationship, Drug; Endothelium, Vascular; Flow Cytometry; HeLa Cells; Histones; Humans; Immunohistochemistry; Indoles; Microscopy, Fluorescence; Microtubules; Models, Chemical; Neoplasm Proteins; Pyrroles; Securin; Spindle Apparatus; Time Factors; Tubulin; Tyrosine

2005
The complement inhibitor, CRIT, undergoes clathrin-dependent endocytosis.
    Experimental cell research, 2005, Oct-15, Volume: 310, Issue:1

    Topics: Arrestins; Carrier Proteins; Clathrin-Coated Vesicles; Colchicine; Complement C2; Complement Inactivator Proteins; Endocytosis; Filipin; Humans; Jurkat Cells; Ligands; Nystatin; Phosphoproteins; Phosphorylation; Signal Transduction; Tyrosine

2005
Antineoplastic agents. 515. Synthesis of human cancer cell growth inhibitors derived from 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene.
    Journal of natural products, 2005, Volume: 68, Issue:8

    Topics: Amides; Anti-Infective Agents; Antineoplastic Agents; Colchicine; Depsipeptides; Dioxoles; Drug Screening Assays, Antitumor; Growth Inhibitors; Humans; Mitosis; Molecular Structure; Oligopeptides; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured; Tyrosine

2005
Colchicine-induced polyploidization depends on tubulin polymerization in c-metaphase cells.
    Protoplasma, 2006, Volume: 227, Issue:2-4

    Topics: Cell Nucleus; Cell Survival; Colchicine; DNA, Plant; In Situ Hybridization, Fluorescence; Metaphase; Microtubules; Plant Roots; Polyploidy; Protein Structure, Quaternary; Secale; Tubulin; Tyrosine

2006
A role for the cytoskeleton in STAT5 activation in MCF7 human breast cancer cells stimulated with EGF.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:10

    Topics: Active Transport, Cell Nucleus; Breast Neoplasms; Cell Line, Tumor; Colchicine; Cytochalasin D; Cytoskeleton; Epidermal Growth Factor; Humans; Kinesins; Microtubules; Phosphorylation; STAT5 Transcription Factor; Tubulin; Tyrosine

2006
Roles of microfilaments and microtubules in paxillin dynamics.
    Biochemical and biophysical research communications, 2006, Oct-06, Volume: 348, Issue:4

    Topics: Actin Cytoskeleton; Animals; Cattle; Cell Movement; Cells, Cultured; Colchicine; Cytochalasin D; Endothelium, Vascular; Focal Adhesions; Microtubules; Paclitaxel; Paxillin; Phosphorylation; Tubulin Modulators; Tyrosine

2006
Microtubules Increase Diastolic Stiffness in Failing Human Cardiomyocytes and Myocardium.
    Circulation, 2020, 03-17, Volume: 141, Issue:11

    Topics: Adult; Aged; Colchicine; Diastole; Elasticity; Female; Heart Failure; Humans; Male; Microtubules; Middle Aged; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Protein Processing, Post-Translational; Sesquiterpenes; Stress, Mechanical; Stroke Volume; Tyrosine; Ventricular Dysfunction, Left; Viscosity

2020
Discovery and engineering of colchicine alkaloid biosynthesis.
    Nature, 2020, Volume: 584, Issue:7819

    Topics: Biosynthetic Pathways; Colchicaceae; Colchicine; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Metabolic Engineering; Metabolomics; Nicotiana; Phenylalanine; Transcriptome; Tyrosine

2020
Genetically encoded live-cell sensor for tyrosinated microtubules.
    The Journal of cell biology, 2020, 10-05, Volume: 219, Issue:10

    Topics: Colchicine; Cytoskeleton; HEK293 Cells; Humans; Microtubule-Associated Proteins; Microtubules; Nocodazole; Protein Processing, Post-Translational; Tubulin; Tyrosine; Vincristine

2020