tyrosine has been researched along with calpain in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.75) | 18.7374 |
| 1990's | 11 (19.30) | 18.2507 |
| 2000's | 31 (54.39) | 29.6817 |
| 2010's | 13 (22.81) | 24.3611 |
| 2020's | 1 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Iacob, S; Novak, RF; Runge-Morris, MA | 1 |
| Ezumi, Y; Okuma, M; Takayama, H | 1 |
| Spencer, MJ; Tidball, JG | 1 |
| Hatanaka, M; Maki, M; Sabe, H; Yamaguchi, R | 1 |
| Alvarez, ME; Bobko, MA; Brownell, JE; Cooper, R; Gillum, AM; Houck, DR; Rodger, CA; Stawicki, MB; Sun, HH; White, CB | 1 |
| Greco, NJ; Huang, C; Ni, Y; Tandon, NN; Wang, T; Zhan, X | 1 |
| Baldin, V; Cans, C; Ducommun, B; Knibiehler, M | 1 |
| Dachary-Prigent, J; Nurden, AT; Pasquet, JM | 1 |
| Hasselgren, PO; Luo, GJ; Wang, JJ; Wang, L | 1 |
| Díez, JA; Elvira, M; Villalobo, A | 1 |
| Falet, H; Pain, S; Rendu, F | 1 |
| Cox, EA; Huttenlocher, A | 1 |
| Best-Belpomme, M; Boelaert, JR; Ferreira, V; Korner, M; Legrand-Poels, S; Piette, J; Schoonbroodt, S | 1 |
| Block, ER; Su, Y | 1 |
| Baudry, M; Bernard, A; Bi, R; Khrestchatisky, M; Rong, Y | 1 |
| Andrabi, SS; Azam, M; Chishti, AH; Kamath, L; Kuliopulos, A; Sahr, KE | 1 |
| Donkor, IO; Sanders, ML | 1 |
| Baudry, M; Bernard, A; Khrestchatisky, M; Lu, X; Rong, Y | 1 |
| Dash, D; Srivastava, K | 1 |
| Bourgeois, M; Bournier, O; Camonis, JH; Dhermy, D; Fournier, CM; Galand, C; Grandchamp, B; Kroviarski, Y; Lecomte, MC; Malbert-Colas, L; Nicolas, G | 1 |
| Barbera, A; Caputi, AP; Centorrino, T; Chatterjee, PK; Ciccolo, A; Cuzzocrea, S; Dugo, L; Fulia, F; Mazzon, E; McDonald, MC; Serraino, I; Thiemermann, C | 1 |
| Cianci, CD; Morrow, JS; Nedrelow, JH | 1 |
| Dean, WL; Wan, TC; Zabe, M | 1 |
| Gomez, TM; Huttenlocher, A; Robles, E | 1 |
| Goto, K; Hayashi, YK; Kawabe, K; Matsumura, T; Nishino, I; Nonaka, I; Ogawa, M; Tagawa, K; Yamanaka, G | 1 |
| Imbert, V; Livolsi, A; Peyron, JF; Siddiqui, A; Waris, G | 1 |
| Forsberg, NE; Purintrapiban, J; Wang, MC | 1 |
| Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Serraino, I; Siriwardena, A; Thiemerman, C; Virlos, I | 1 |
| Giasson, BI; Hodara, R; Ischiropoulos, H; Lee, VM; Lynch, DR; Mishizen-Eberz, AJ; Norris, EH | 1 |
| Chen, WY; Huang, CJ; Lee, FY; Lin, SY; Sheu, WH | 1 |
| Bahr, BA; Blomgren, K; Hagberg, H; Shibata, M; Uchiyama, Y; Wang, X; Xu, F; Zhu, C | 1 |
| Giasson, BI; Hodara, R; Ischiropoulos, H; Lee, VM; Lynch, DR; Mishizen-Eberz, AJ; Norris, EH; Trojanowski, JQ | 1 |
| Brattain, MG; Cookson, MM; Hauser, J; Omar, Y; Sawhney, RS | 1 |
| Deng, Y; Hall, ED; Mbye, LH; Singh, IN; Sullivan, PG | 1 |
| DeLuca, GC; Diaz-Sanchez, M; Esiri, MM; Williams, K | 1 |
| Harper, AG; Sage, SO | 1 |
| Chishti, A; Du, X; Flevaris, P; Lam, SC; Phillips, DR; Stojanovic, A; Xi, X | 1 |
| Hall, ED; Rabchevsky, AG; Xiong, Y | 1 |
| Gustavsson, M; Hagberg, H; Karlsson, JO; Lapatto, R; Mallard, C; Nie, C; Romero, R; Sandberg, M; Svedin, P; Wang, X; Zhu, C | 1 |
| Deng, Y; Gao, X; Hall, ED; Thompson, BM | 1 |
| Ishida, A; Ishida-Nakajima, W; Kawamura, M; Miura, S; Oguma, R; Ohmura, A; Sato, Y; Takahashi, T | 1 |
| Asano, S; Baba, M; Kawasaki, N; Kawasaki, T; Ma, BY; Matsumoto, S; Nonaka, M; Yoshida, K | 1 |
| Connolly, Y; Gorgoulis, VG; Liontos, M; Malliri, A; Rooney, C; Whetton, AD; Woodcock, SA; Zoumpourlis, V | 1 |
| Shao, H; Wells, A; Wu, C | 1 |
| Callero, MA; Chamorro, ME; Nesse, AB; Vittori, DC; Vota, DM; Wenker, SD | 1 |
| Beningo, KA; Kang, CM; Menon, S | 1 |
| Babu, PP; Chaitanya, GV; Eeka, P | 1 |
| Blundell, MP; Calle, Y; Cory, GO; Jones, GE; Macpherson, L; Monypenny, J; Thrasher, AJ; Tomé-García, J | 1 |
| Chan, T; Francis, GA; Hossain, MA; Ngeth, S; Oda, MN | 1 |
| Chishti, AH; Herman, IM; Kuchay, SM; Marinkovic, M; Wieschhaus, AJ | 1 |
| De Simoni, S; Goemaere, J; Hermans, E; Knoops, B; Linard, D | 1 |
| Ahmed, Z; Donkor, ON; Street, WA; Vasiljevic, T | 1 |
| Annamalai, B; Choi, S; Singh, AK; Singh, I; Won, JS | 1 |
| Abbott, T; Eipper, BA; Kiraly, DD; Koleske, AJ; Lam, TT; Levy, AD; Machida, K; Mains, RE; Miller, MB; Wu, YI; Yan, Y | 1 |
| Baudry, M; Bi, X; Hall, RA; Kamgar-Parsi, A; Lee, M; Wang, Y | 1 |
| Lauffenburger, D; Shao, H; Wang, A; Wells, A | 1 |
| Abu-Gharbieh, E; Abushawish, KYI; Al-Hroub, HM; Alzoubi, KH; Bustanji, Y; El-Huneidi, W; Elgendy, SM; Giddey, AD; Mousa, M; Omar, HA; Semreen, MH; Soares, NC; Soliman, SSM | 1 |
1 review(s) available for tyrosine and calpain
| Article | Year |
|---|---|
Regulation of integrin-mediated adhesion during cell migration.
Topics: Calcium; Calpain; Cell Adhesion; Cell Movement; Extracellular Matrix; Fibroblasts; Integrins; Neutrophils; Phosphorylation; Tyrosine | 1998 |
56 other study(ies) available for tyrosine and calpain
| Article | Year |
|---|---|
Characterization of hydrazine-stimulated proteolysis in human erythrocytes.
Topics: Adenosine Triphosphate; Adult; Amitrole; Antioxidants; Blood Proteins; Calpain; Electron Transport; Enzyme Precursors; Erythrocytes; Humans; Hydrazines; Hydrogen Peroxide; In Vitro Techniques; Methemoglobin; Tyrosine | 1988 |
Differential regulation of protein-tyrosine phosphatases by integrin alpha IIb beta 3 through cytoskeletal reorganization and tyrosine phosphorylation in human platelets.
Topics: Adult; Biological Transport; Blood Platelets; Blood Proteins; Calpain; Cytochalasin D; Cytoskeleton; Gene Expression Regulation, Enzymologic; Humans; Integrins; Isoenzymes; Models, Biological; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Subcellular Fractions; Thrombasthenia; Thrombin; Tyrosine | 1995 |
PDGF stimulation induces phosphorylation of talin and cytoskeletal reorganization in skeletal muscle.
Topics: Animals; Calpain; Cell Line; Cytoskeleton; Enzyme Activation; Fluorescent Antibody Technique; Muscles; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Receptors, Platelet-Derived Growth Factor; Talin; Tyrosine | 1993 |
Unphosphorylated and tyrosine-phosphorylated forms of a focal adhesion protein, paxillin, are substrates for calpain II in vitro: implications for the possible involvement of calpain II in mitosis-specific degradation of paxillin.
Topics: 3T3 Cells; Animals; Calpain; Cell Adhesion Molecules; Cytoskeletal Proteins; Humans; Mice; Mitosis; Paxillin; Phosphoproteins; Phosphorylation; Tyrosine | 1994 |
Isolation and structure elucidation of two new calpain inhibitors from Streptomyces griseus.
Topics: Calpain; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Oligopeptides; Piperazines; Streptomyces griseus; Tyrosine | 1994 |
Proteolysis of platelet cortactin by calpain.
Topics: Blood Platelets; Calpain; Collagen; Cortactin; Humans; Microfilament Proteins; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins pp60(c-src); Tyrosine | 1997 |
Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation.
Topics: Calpain; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cysteine Endopeptidases; HeLa Cells; Humans; Leupeptins; Multienzyme Complexes; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Threonine; Tyrosine | 1997 |
Microvesicle release is associated with extensive protein tyrosine dephosphorylation in platelets stimulated by A23187 or a mixture of thrombin and collagen.
Topics: Blood Platelets; Blood Proteins; Calcimycin; Calcium; Calpain; Collagen; Enzyme Activation; Hemostatics; Humans; Hydrolysis; Ionophores; Kinetics; Phosphatidylserines; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Stimulation, Chemical; Thrombin; Tyrosine | 1998 |
Dexamethasone stimulates proteasome- and calcium-dependent proteolysis in cultured L6 myotubes.
Topics: Adenosine Triphosphate; Animals; Calcium; Calpain; Cathepsin B; Cathepsin D; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Deoxyglucose; Dexamethasone; Leucine; Leupeptins; Methylamines; Mifepristone; Multienzyme Complexes; Muscle, Skeletal; Proteasome Endopeptidase Complex; Proteins; Rats; Tyrosine; Ubiquitins | 1998 |
The epidermal growth factor receptor tyrosine kinase phosphorylates connexin32.
Topics: Animals; Blotting, Western; Calmodulin; Calpain; Cell Membrane; Chromatography, Affinity; Connexins; Epidermal Growth Factor; ErbB Receptors; Gap Junction beta-1 Protein; Gap Junctions; Kinetics; Liver; Male; Mice; Phosphoamino Acids; Phosphorylation; Rats; Rats, Sprague-Dawley; Tyrosine | 1998 |
Tyrosine unphosphorylated platelet SHP-1 is a substrate for calpain.
Topics: Blood Platelets; Calcimycin; Calcium Chloride; Calpain; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Platelet Activation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Substrate Specificity; Thrombin; Tyrosine; Vanadates | 1998 |
Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress.
Topics: Animals; Calpain; Casein Kinase II; Cysteine Endopeptidases; DNA; DNA-Binding Proteins; Enzyme Activation; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Mice; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Peptide Fragments; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Serine; Tumor Cells, Cultured; Tyrosine | 2000 |
Role of calpain in hypoxic inhibition of nitric oxide synthase activity in pulmonary endothelial cells.
Topics: Animals; Calpain; Caveolin 1; Caveolins; Cells, Cultured; Cysteine Proteinase Inhibitors; Dipeptides; Endothelium, Vascular; HSP90 Heat-Shock Proteins; Hypoxia; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Artery; Serine; Swine; Tyrosine | 2000 |
Src-mediated tyrosine phosphorylation of NR2 subunits of N-methyl-D-aspartate receptors protects from calpain-mediated truncation of their C-terminal domains.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calpain; Gene Library; Molecular Sequence Data; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; src Homology Domains; Synaptic Membranes; Tyrosine | 2000 |
Disruption of the mouse mu-calpain gene reveals an essential role in platelet function.
Topics: Adenosine Diphosphate; Animals; Antigens, CD; Blood Platelets; Blood Proteins; Blotting, Western; Calcimycin; Calpain; Collagen; Contractile Proteins; Enzyme Precursors; Filamins; Gene Silencing; Integrin beta3; Mice; Mice, Mutant Strains; Microfilament Proteins; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Signal Transduction; Talin; Thrombin; Tyrosine | 2001 |
Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus.
Topics: Animals; Calpain; Cysteine Proteinase Inhibitors; Erythrocytes; Glycoproteins; Magnetic Resonance Spectroscopy; Piperazines; Streptomyces griseus; Swine; Tyrosine | 2001 |
Tyrosine phosphorylation of ionotropic glutamate receptors by Fyn or Src differentially modulates their susceptibility to calpain and enhances their binding to spectrin and PSD-95.
Topics: Animals; Calpain; Carrier Proteins; Disks Large Homolog 4 Protein; Drug Resistance; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Spectrin; Tyrosine | 2001 |
Changes in membrane microenvironment and signal transduction in platelets from NIDDM patients-a pilot study.
Topics: Adult; Blood Platelets; Calcimycin; Calpain; Case-Control Studies; Cell Membrane; Diabetes Mellitus, Type 2; Epinephrine; Humans; Middle Aged; Phosphorylation; Pilot Projects; Platelet Activation; Platelet Aggregation; Reference Values; Signal Transduction; Tyrosine | 2002 |
Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain.
Topics: Amino Acid Sequence; Animals; Calpain; Cell Fractionation; Cell Line; Cytoskeleton; Male; Molecular Sequence Data; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Sequence Alignment; Spectrin; Two-Hybrid System Techniques; Tyrosine; Yeasts | 2002 |
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat.
Topics: Animals; Calpain; Cell Movement; Cyclooxygenase 2; Dose-Response Relationship, Drug; Glycoproteins; Immunohistochemistry; Intestinal Mucosa; Intestines; Isoenzymes; Liver; Lung; Male; Malondialdehyde; Multiple Organ Failure; Neutrophils; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peritoneum; Peritonitis; Peroxidase; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tyrosine; Zymosan | 2002 |
c-Src binds alpha II spectrin's Src homology 3 (SH3) domain and blocks calpain susceptibility by phosphorylating Tyr1176.
Topics: Animals; Apoptosis; Binding Sites; Calcium; Calpain; Cell Line; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endocytosis; Glutathione Transferase; Kinetics; Marine Toxins; Models, Biological; Oxocins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Spectrin; src Homology Domains; src-Family Kinases; Time Factors; Tyrosine; Vanadates | 2003 |
Plasma membrane Ca2+-ATPase isoform 4b is phosphorylated on tyrosine 1176 in activated human platelets.
Topics: Amino Acid Sequence; Blood Platelets; Calcium-Transporting ATPases; Calpain; Cation Transport Proteins; Cell Membrane; Erythrocyte Membrane; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Phosphorylation; Plasma Membrane Calcium-Transporting ATPases; Platelet Activation; Protein Isoforms; Protein-Tyrosine Kinases; Tyrosine | 2003 |
Filopodial calcium transients regulate growth cone motility and guidance through local activation of calpain.
Topics: Animals; Calcium; Calcium Signaling; Calpain; Cell Adhesion; Cells, Cultured; Cytoskeleton; Growth Cones; Neurons; Phosphorylation; Phosphotyrosine; Pseudopodia; Spinal Cord; src-Family Kinases; Substrate Specificity; Tyrosine; Xenopus | 2003 |
Protein and gene analyses of dysferlinopathy in a large group of Japanese muscular dystrophy patients.
Topics: Age of Onset; Alanine; Blotting, Western; Calpain; Cysteine; Cytoskeletal Proteins; DNA Mutational Analysis; Dysferlin; Dystroglycans; Dystrophin; Glycine; Humans; Immunohistochemistry; Japan; Membrane Glycoproteins; Membrane Proteins; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophies; Mutation; Neuromuscular Diseases; Sarcoglycans; Sequence Analysis, Protein; Tyrosine | 2003 |
Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease.
Topics: Actins; Blotting, Western; Calcium; Calpain; Cell Line, Tumor; Cell Nucleus; Genome; Humans; I-kappa B Proteins; Immunoblotting; Luciferases; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Oligonucleotides; Oxidative Stress; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Transfection; Tyrosine; Viral Nonstructural Proteins | 2003 |
Degradation of sarcomeric and cytoskeletal proteins in cultured skeletal muscle cells.
Topics: Actinin; Animals; Calpain; Cells, Cultured; Cysteine Endopeptidases; Cytoskeletal Proteins; Hydrolysis; Isotope Labeling; Lysosomes; Multienzyme Complexes; Muscle Cells; Muscle Fibers, Skeletal; Protease Inhibitors; Proteasome Endopeptidase Complex; Rats; Sarcomeres; Tropomyosin; Tyrosine | 2003 |
Calpain I inhibitor ameliorates the indices of disease severity in a murine model of cerulein-induced acute pancreatitis.
Topics: Acute Disease; Analysis of Variance; Animals; Blotting, Western; Calpain; Ceruletide; Disease Models, Animal; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Mice; NF-kappa B; Nitric Oxide Synthase; Pancreatitis; Poly(ADP-ribose) Polymerases; Random Allocation; Respiratory Distress Syndrome; Tyrosine | 2004 |
Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation.
Topics: alpha-Synuclein; Animals; Calpain; Humans; Insulin; Lipid Metabolism; Mice; Molecular Chaperones; Nerve Tissue Proteins; Nitrates; Oxygen; Proteasome Endopeptidase Complex; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Quaternary; Synucleins; Tyrosine | 2004 |
Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-alpha.
Topics: Animals; Blotting, Western; Body Weight; Calpain; Cathepsins; Disease Models, Animal; Gene Expression; Ligation; Liver; Liver Cirrhosis, Biliary; Male; Methylhistidines; Muscle Proteins; Muscle, Skeletal; Myofibrils; NF-kappa B; Nuclear Proteins; Proteasome Endopeptidase Complex; Protein Subunits; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin; Ubiquitin-Conjugating Enzymes | 2005 |
The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.
Topics: Aging; Animals; Apoptosis; Apoptosis Inducing Factor; Autophagy; Brain Injuries; Calpain; Caspase 3; Caspases; Cell Death; Cytochromes c; Disease Models, Animal; Flavoproteins; Hypoxia-Ischemia, Brain; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mitochondria; Necrosis; Neurons; Protein Transport; Tyrosine | 2005 |
Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein.
Topics: alpha-Synuclein; Calpain; Chymotrypsin; Humans; Hydrolysis; Microscopy, Immunoelectron; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Parkinson Disease; Peptide Fragments; Peroxynitrous Acid; Recombinant Proteins; Solubility; Synucleins; Tyrosine | 2005 |
Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway.
Topics: Biotinylation; Butadienes; Calpain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Cytochalasin D; Electric Impedance; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alpha2; Mitogen-Activated Protein Kinases; Nitriles; Nucleic Acid Synthesis Inhibitors; Oligonucleotides, Antisense; Phosphorylation; Point Mutation; Precipitin Tests; Protein Structure, Tertiary; Signal Transduction; Substrate Specificity; Tyrosine | 2006 |
Time course of post-traumatic mitochondrial oxidative damage and dysfunction in a mouse model of focal traumatic brain injury: implications for neuroprotective therapy.
Topics: Animals; Blotting, Northern; Brain Hemorrhage, Traumatic; Calpain; Cytoskeleton; Male; Membrane Lipids; Membrane Proteins; Mice; Microscopy, Electron; Mitochondria; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Oxygen Consumption; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine | 2006 |
Protein co-expression with axonal injury in multiple sclerosis plaques.
Topics: Amyloid beta-Peptides; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Axons; Biomarkers; Brain; Calpain; CD3 Complex; Humans; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Multiple Sclerosis; Nitric Oxide Synthase Type II; Osteopontin; Plaque, Amyloid; Proteins; Sialoglycoproteins; T-Lymphocytes; Tyrosine | 2006 |
A role for the intracellular protease calpain in the activation of store-operated calcium entry in human platelets.
Topics: Blood Platelets; Calcium; Calcium Signaling; Calpain; Cells, Cultured; Cysteine Proteinase Inhibitors; Dipeptides; Drug Interactions; Humans; Phosphorylation; Platelet Activation; Strontium; Thapsigargin; Thrombin; Tyrosine | 2007 |
Tyrosine phosphorylation of the integrin beta 3 subunit regulates beta 3 cleavage by calpain.
Topics: Amino Acid Sequence; Animals; Calpain; Cell Movement; Cells, Cultured; Humans; Integrin beta3; Mice; Mice, Mutant Strains; Molecular Sequence Data; Phosphorylation; Signal Transduction; Tyrosine | 2006 |
Role of peroxynitrite in secondary oxidative damage after spinal cord injury.
Topics: Aldehydes; Animals; Biomarkers; Calcium Signaling; Calpain; Disease Progression; Female; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Nerve Degeneration; Nitric Oxide; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spectrin; Spinal Cord Injuries; Time Factors; Tyrosine; Up-Regulation | 2007 |
N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic-ischemic brain injury.
Topics: Animals; Animals, Newborn; Apoptosis; Calpain; Caspases; Cystine; Enzyme Activation; Glutathione; Hypoxia-Ischemia, Brain; Isoprostanes; Lipopolysaccharides; Membrane Proteins; Neuroprotective Agents; Oxidation-Reduction; Rats; Rats, Wistar; Thioredoxins; Tyrosine | 2007 |
Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.
Topics: Aldehydes; Animals; Brain; Brain Injuries; Calcium; Calpain; Cerebral Cortex; Cytoskeleton; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Oxidative Stress; Peroxynitrous Acid; Spectrin; Time Factors; Tissue Distribution; Tyrosine | 2007 |
Ascorbic acid protects the newborn rat brain from hypoxic-ischemia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Apoptosis; Ascorbic Acid; Blotting, Western; Brain; Brain Ischemia; Calpain; Carrier Proteins; Caspase 3; Enzyme Activation; In Situ Nick-End Labeling; Microfilament Proteins; Microscopy, Electron; Necrosis; Neurons; Neuroprotective Agents; Rats; Tyrosine | 2009 |
The lectin Jacalin induces human B-lymphocyte apoptosis through glycosylation-dependent interaction with CD45.
Topics: Apoptosis; B-Lymphocytes; Calcium; Calpain; Carbohydrates; Cells, Cultured; Dose-Response Relationship, Immunologic; Glycosylation; Humans; Leukocyte Common Antigens; Phosphorylation; Plant Lectins; Protein Tyrosine Phosphatases; Receptors, Mitogen; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2009 |
SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.
Topics: Adherens Junctions; Animals; Calpain; Cell Line; Cell Movement; Cloning, Molecular; Dogs; Extracellular Signal-Regulated MAP Kinases; GRB2 Adaptor Protein; Guanine Nucleotide Exchange Factors; Humans; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Neoplasm Invasiveness; Neoplasms; Oncogene Protein pp60(v-src); Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; SOS1 Protein; src Homology Domains; src-Family Kinases; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Time Factors; Transfection; Tyrosine | 2009 |
Phosphorylation of alpha-actinin 4 upon epidermal growth factor exposure regulates its interaction with actin.
Topics: Actinin; Actins; Animals; Calpain; Cell Adhesion; Cell Line; Cell Movement; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Giant Cells; Humans; MAP Kinase Signaling System; Mice; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tyrosine | 2010 |
Calcium as a mediator between erythropoietin and protein tyrosine phosphatase 1B.
Topics: Calcium; Calpain; Cell Differentiation; Cell Line; Cell Proliferation; Erythropoietin; Humans; Intracellular Space; Isoenzymes; Molecular Weight; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Messenger; TRPC Cation Channels; TRPC6 Cation Channel; Tyrosine | 2011 |
Galectin-3 secretion and tyrosine phosphorylation is dependent on the calpain small subunit, Calpain 4.
Topics: Animals; Calpain; Cell Line; Cell Movement; Fibroblasts; Focal Adhesions; Galectin 3; Mice; Phosphorylation; Tyrosine | 2011 |
Proteolytic breakdown of cytoskeleton induces neurodegeneration during pathology of murine cerebral malaria.
Topics: Animals; Blotting, Western; Calpain; Caspase 1; Cytoskeletal Proteins; Cytoskeleton; Epoxy Compounds; Fluorescent Antibody Technique; Immunohistochemistry; Immunoprecipitation; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Nerve Degeneration; Peptide Hydrolases; Plasmodium berghei; Proteolysis; Receptor Cross-Talk; Tyrosine | 2011 |
Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly.
Topics: Actin Cytoskeleton; Animals; Calpain; Cell Adhesion; Cell Membrane Structures; Cell Movement; Cells, Cultured; Dendritic Cells; Fluorescent Antibody Technique; Macrophages; Mice; Mice, Inbred C57BL; Myeloid Cells; Phosphorylation; Protein Binding; Tyrosine; Wiskott-Aldrich Syndrome Protein | 2012 |
Lipid-bound apolipoproteins in tyrosyl radical-oxidized HDL stabilize ABCA1 like lipid-free apolipoprotein A-I.
Topics: Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Calpain; Cell Membrane; Cells, Cultured; Cholesterol; Enteropeptidase; Esterification; Gene Expression; Humans; Lipoproteins, HDL; Oxidation-Reduction; Protein Binding; Protein Stability; Protein Transport; Proteolysis; Tyrosine | 2012 |
Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading.
Topics: Animals; Blood Platelets; Calpain; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Shape; Collagen; Enzyme Activation; Fibrinogen; Gene Silencing; Genotype; Hemostasis; Humans; Mice; Mice, Knockout; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microscopy, Interference; Phenotype; Phosphorylation; Protease Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 1; rac1 GTP-Binding Protein; Recombinant Proteins; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Substrate Specificity; Time Factors; Tyrosine | 2012 |
Mitochondrial peroxiredoxin-5 as potential modulator of mitochondria-ER crosstalk in MPP+-induced cell death.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Apoptosis; Boron Compounds; Calcium; Calpain; Caspase 3; Caspase 9; Cell Line, Tumor; DNA, Mitochondrial; Dopamine Agents; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation; Humans; Hydro-Lyases; Mice; Mitochondria; Neuroblastoma; Peroxiredoxins; Reactive Oxygen Species; RNA, Small Interfering; Subcellular Fractions; Transfection; Tyrosine | 2013 |
Activity of endogenous muscle proteases from 4 Australian underutilized fish species as affected by ionic strength, pH, and temperature.
Topics: Animals; Australia; Calpain; Epoxy Compounds; Fishes; Food Storage; Hydrogen-Ion Concentration; Meat; Muscle, Skeletal; Osmolar Concentration; Peptide Hydrolases; Temperature; Tyrosine | 2013 |
S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion.
Topics: Analysis of Variance; Animals; Brain; Brain Ischemia; Calpain; Chronic Disease; Cyclin-Dependent Kinase 5; Disease Models, Animal; Glycogen Synthase Kinase 3; Neuroprotective Agents; Phosphorylation; Rats; S-Nitrosoglutathione; Synaptosomes; tau Proteins; Tyrosine | 2015 |
Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.
Topics: Animals; Binding Sites; Calpain; Cocaine; Dopamine Uptake Inhibitors; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Male; Mass Spectrometry; Nucleus Accumbens; PDZ Domains; Phosphorylation; Prefrontal Cortex; Protein Isoforms; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; src Homology Domains; Tyrosine | 2017 |
The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation.
Topics: Animals; Brain Injuries, Traumatic; Calpain; Mice; Mice, Knockout; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 13; tau Proteins; Tyrosine | 2017 |
Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain.
Topics: Actinin; Amino Acid Substitution; Calpain; Cell Line; Cell Line, Tumor; Cell Movement; Enzyme Activation; Focal Adhesion Kinase 1; Gene Knockdown Techniques; Green Fluorescent Proteins; Humans; Melanoma; Mutation; Neoplasm Invasiveness; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Protein Stability; Proteolysis; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA Interference; Signal Transduction; Tyrosine | 2018 |
Multi-Omics Analysis Revealed a Significant Alteration of Critical Metabolic Pathways Due to Sorafenib-Resistance in Hep3B Cell Lines.
Topics: Alanine; Amino Acids; Antineoplastic Agents; Biomarkers; Calpain; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Folic Acid Antagonists; Glucose; Humans; L-Iditol 2-Dehydrogenase; Liver Neoplasms; Metabolic Networks and Pathways; Nucleotides; Phosphatidylcholines; Proline; Protein Kinase Inhibitors; Proteome; Proteomics; Sorafenib; Succinic Acid; Superoxide Dismutase; Tyrosine; Ubiquitin Thiolesterase; Uridine Diphosphate | 2022 |