tyrosine has been researched along with bisindolylmaleimide i in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (54.17) | 18.2507 |
| 2000's | 11 (45.83) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brugge, JS; Cunningham, M; Ginsberg, MH; Haimovich, B; Lipfert, L; Parsons, JT; Shattil, SJ | 1 |
| Falet, H; Rendu, F | 1 |
| Mitchell, R; Simpson, J; Wolbers, B | 1 |
| Leslie, CC; Qiu, ZH | 1 |
| Rozengurt, E; Sinnett-Smith, J; Valverde, AM; Zachary, I | 1 |
| Haimovich, B; Ji, P; Kaneshiki, N | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 1 |
| Petryniak, MA; Slack, BE; Wurtman, RJ | 1 |
| Abedi, H; Zachary, I | 1 |
| Alimandi, M; Ellmore, N; Gutkind, JS; Heidaran, MA; Kazlauskas, A; Li, W; Pierce, JH; Valius, M; Zhang, J | 1 |
| García, LJ; González, A; Jensen, RT; Rosado, JA | 1 |
| Fagerström, S; Nånberg, E; Påhlman, S | 1 |
| Gear, AR; Polanowska-Grabowska, R | 1 |
| Azevedo, JL; Cortright, RN; Dohm, GL; Itani, SI; Pories, WJ; Sinha, M; Zhou, Q | 1 |
| Aguilera, J; Gil, C; Najib, A; Pelliccioni, P | 1 |
| Massoumi, R; Sjölander, A | 1 |
| Chibalin, AV; Féraille, E; Kovalenko, MV; Ryder, JW; Wallberg-Henriksson, H; Zierath, JR | 1 |
| Brady, HR; Godson, C; Martin, F; McMahon, B; Mitchell, D; Shattock, R | 1 |
| Chain, BM; Cho, JY; Katz, DR | 1 |
| Andersson, T; Dib, K; Melander, F | 1 |
| Bustelo, XR; Caloca, MJ; Zugaza, JL | 1 |
| Ferjan, I; Stempelj, M | 1 |
| Artemenko, Y; Gagnon, A; Ibrahim, S; Sorisky, A | 1 |
| Bhavaraju, K; Daniel, JL; Kim, S; Kunapuli, SP | 1 |
24 other study(ies) available for tyrosine and bisindolylmaleimide i
| Article | Year |
|---|---|
Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Alprostadil; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cytoplasm; Egtazic Acid; Epinephrine; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Indoles; Indomethacin; Maleimides; Models, Biological; Phosphorylation; Phosphotyrosine; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Thromboxane A2; Tyrosine; Vasodilator Agents | 1994 |
Calcium mobilisation controls tyrosine protein phosphorylation independently of the activation of protein kinase C in human platelets.
Topics: Blood Platelets; Calcium; Edetic Acid; Enzyme Activation; Humans; Indoles; Maleimides; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Aggregation; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tyrosine | 1994 |
LHRH-induced tyrosine phosphorylation and MAP kinase activation in alpha T3-1 cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Gonadotropin-Releasing Hormone; Immunoblotting; Indoles; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, LHRH; Signal Transduction; Tyrosine | 1995 |
Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Indoles; Isoenzymes; Macrophages, Peritoneal; Maleimides; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Zymosan | 1994 |
Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.
Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Cytoskeleton; Diglycerides; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Indoles; Intracellular Signaling Peptides and Proteins; Kinetics; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Terpenes; Thapsigargin; Tyrosine | 1993 |
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Size; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1996 |
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
Topics: Amyloid beta-Protein Precursor; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Isoflavones; Kidney; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tyrosine | 1996 |
Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells.
Topics: Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Lymphokines; Maleimides; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
PLC-gamma activation is required for PDGF-betaR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells.
Topics: Binding Sites; Cell Differentiation; DNA; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Monocytes; Mutation; Phenylalanine; Phospholipase C gamma; Phosphorylation; Platelet-Derived Growth Factor; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Stem Cells; Type C Phospholipases; Tyrosine | 1997 |
Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho.
Topics: Actins; Animals; Calcimycin; Calcium; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Models, Biological; Pancreas; Paxillin; Phospholipases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; rho GTP-Binding Proteins; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine | 1997 |
Protein kinase C-dependent tyrosine phosphorylation of p130cas in differentiating neuroblastoma cells.
Topics: Bucladesine; Cell Differentiation; Crk-Associated Substrate Protein; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Neuroblastoma; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Proteins; Proto-Oncogene Proteins pp60(c-src); Retinoblastoma-Like Protein p130; src-Family Kinases; Tumor Cells, Cultured; Tyrosine | 1998 |
Activation of protein kinase C is required for the stable attachment of adherent platelets to collagen but is not needed for the initial rapid adhesion under flow conditions.
Topics: Animals; Antibodies; Blood Flow Velocity; Blood Platelets; Blood Proteins; Carbazoles; Carcinogens; Cell Adhesion Molecules; Collagen; Enzyme Inhibitors; Enzyme Precursors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Integrins; Intracellular Signaling Peptides and Proteins; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Protein Conformation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptors, Collagen; Skin; Stimulation, Chemical; Syk Kinase; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Protein kinase C modulates insulin action in human skeletal muscle.
Topics: Abdominal Muscles; Adult; Biological Transport; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Glucose; Humans; Indoles; Insulin; Insulin Resistance; Maleimides; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Receptor, Insulin; Reference Values; Tyrosine | 2000 |
Serotonin transporter phosphorylation modulated by tetanus toxin.
Topics: Animals; Biological Transport; Brain; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Isotope Labeling; Maleimides; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Serine; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tetanus Toxin; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases; Tyrosine | 2000 |
Leukotriene D(4) affects localisation of vinculin in intestinal epithelial cells via distinct tyrosine kinase and protein kinase C controlled events.
Topics: Actins; alpha Catenin; Cadherins; Carcinogens; Cell Adhesion; Cell Line; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesions; Humans; Indoles; Integrin beta1; Intestinal Mucosa; Leukotriene D4; Maleimides; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Tetradecanoylphorbol Acetate; Tyrosine; Vinculin | 2001 |
Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle.
Topics: Animals; Cell Membrane; Enzyme Inhibitors; Extracellular Space; Glucose; Indoles; Insulin; Male; Maleimides; Muscle, Skeletal; Phosphoamino Acids; Phosphorylation; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Tissue Distribution; Tyrosine | 2001 |
Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation.
Topics: Animals; Cell Division; Cells, Cultured; CHO Cells; Cricetinae; Dicarboxylic Acids; Enzyme Inhibitors; Glomerular Mesangium; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Leukotriene Antagonists; Leukotriene D4; Lipoxins; Maleimides; Phosphorylation; Protein Kinase C; Receptor Cross-Talk; Receptors, Cell Surface; Receptors, Leukotriene; Receptors, Platelet-Derived Growth Factor; Tyrosine | 2002 |
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2003 |
Engagement of beta2 integrins recruits 14-3-3 proteins to c-Cbl in human neutrophils.
Topics: 14-3-3 Proteins; CD18 Antigens; Cell Adhesion; Enzyme Inhibitors; Humans; Indoles; Maleimides; Neutrophils; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Serine; Signal Transduction; src-Family Kinases; Tyrosine; Tyrosine 3-Monooxygenase; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
Inverted signaling hierarchy between RAS and RAC in T-lymphocytes.
Topics: Cell Cycle Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Estrenes; Guanine Nucleotide Exchange Factors; Humans; Indoles; Jurkat Cells; Maleimides; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Pyrrolidinones; rac1 GTP-Binding Protein; ras Proteins; Signal Transduction; T-Lymphocytes; Type C Phospholipases; Tyrosine | 2004 |
Signaling pathway in nerve growth factor induced histamine release from rat mast cells.
Topics: Analysis of Variance; Androstadienes; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Flavonoids; Histamine; Imidazoles; Indoles; Male; Maleimides; Mast Cells; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tyrosine; Wortmannin | 2005 |
Regulation of PDGF-stimulated SHIP2 tyrosine phosphorylation and association with Shc in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; Amino Acid Substitution; Animals; Cell Division; Drug Interactions; Enzyme Inhibitors; Humans; Indoles; Inositol Polyphosphate 5-Phosphatases; Maleimides; Mice; Mutagenesis, Site-Directed; Phosphatidylinositol Phosphates; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transfection; Tyrosine | 2007 |
Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets.
Topics: Adaptor Proteins, Signal Transducing; Blood Platelets; Blotting, Western; Crotalid Venoms; Cytoplasmic Granules; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Lectins, C-Type; Maleimides; Membrane Proteins; Oligopeptides; Phospholipase C gamma; Phosphorylation; Platelet Function Tests; Protein Kinases; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Stilbenes; Sulfonamides; Syk Kinase; Thromboxanes; Tyrosine | 2008 |