tyrosine has been researched along with asparagine in 259 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 96 (37.07) | 18.7374 |
| 1990's | 57 (22.01) | 18.2507 |
| 2000's | 73 (28.19) | 29.6817 |
| 2010's | 29 (11.20) | 24.3611 |
| 2020's | 4 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Hosbach, HA; Kubli, E | 1 |
| Prasad, M | 1 |
| Katze, JR | 2 |
| Lee, SG; Lipmann, F | 1 |
| Meinke, G; Spiegelberg, HL | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Crain, PF; Harada, F; Kasai, H; Liehr, JG; McCloskey, JA; Nishimura, S; Oashi, Z; Oppenheimer, NJ; von Minden, DL | 1 |
| Chellemi, F | 1 |
| Larsson, LE; Melin, P; Ragnarsson, U | 1 |
| Ferroni, R; Guggi, A; Rocchi, R; Tomatis, R | 1 |
| Balaji, PV; Rao, VS | 1 |
| Chen, J; Matthews, KS | 1 |
| Elsas, LJ; Griffin, LD; Langley, SD; Longo, N; Shuster, RC | 1 |
| Chuang, DT; Cox, RP; Fisher, CR; Fisher, CW | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| de Haas, GH; Franken, PA; Hendriks, R; Kuipers, OP; Verheij, HM | 1 |
| He, YW; Khorana, HG; Marti, T; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Arous, N; Blouquit, Y; Edelstein, SJ; Galacteros, F; Kister, J; Poyart, C; Schaad, O | 1 |
| Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Harris, GW; Howlin, B; Moss, DS | 1 |
| Crabb, DW; Edenberg, HJ; Goodwin, GW; Harris, RA; Kuntz, MJ; Zhang, B | 1 |
| Parham, P | 1 |
| Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Wolf-Novak, LC; Ziegler, EE | 1 |
| Frelinger, JA; Hutchison, CA; Murray, R | 1 |
| Katayama, K; Nakamura, T; Obayashi, A; Sano, S; Ueno, M | 1 |
| Arquilla, ER; Miles, PV; Morris, JW | 1 |
| Fischbach, R; Harrer, G | 1 |
| Jaton, JC | 1 |
| Tener, GM; White, BN | 1 |
| Dikow, A; Lolova, I | 1 |
| Doyle, AE; Murray, M; Osborn, EC | 1 |
| Baliga, BS; Borek, E; Srinivasan, PR; Weinstein, IB | 1 |
| Grunberger, D; Morris, HP; Srinivasan, D; Srinivasan, PR; Weinstein, IB | 1 |
| Fleischer, EB; Grimes, CJ; Piszkiewicz, D | 1 |
| Crippa, PR; Tedeschi, RA; Vecli, A | 1 |
| Litwack, G; Miller, JE | 1 |
| Castillo, CL; Mayer, A; Ogawa, S; Shulman, RG | 1 |
| Manning, M; Sawyer, WH | 1 |
| Luborsky, SW; Parrott, CL; Shifrin, S | 1 |
| Parrott, CL; Shifrin, S | 1 |
| Jaenicke, L; Menge, U | 1 |
| Halpern, YS | 1 |
| Pittsyn, OB | 1 |
| Ali, A; Faesel, JH; Sarantakis, D; Stevenson, D; Weinstein, B | 1 |
| Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
| Klemer, A; Kraska, B | 1 |
| Adibi, SA; Amin, PM; Modesto, TA; Morse, EL | 1 |
| Liao, TH; Moore, S; Salnikow, J; Stein, WH | 1 |
| Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
| Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
| Merz, WG; Silva-Hutner, M; Weitzman, I | 1 |
| Kalnitsky, G; Spadari, S; Subramanian, AR | 1 |
| Berger, H; Yanofsky, C | 1 |
| Morihara, K; Tsuzuki, H | 1 |
| Benuck, M; Lajtha, A; Stern, F | 2 |
| Lloyd, KO; Merz, WG; Silva-Hutner, M | 1 |
| Alden, RA; Kraut, J; Wright, CS | 1 |
| Gross, W; Ring, K | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Hersh, EM; Ohno, R | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
| Graeber, W | 1 |
| Bromwell, KE; Guroff, G | 1 |
| Lohrenz, FN; Tewksbury, DA | 1 |
| Cohen, JS; Putter, I; Smith, JL; Vandenheuvel, WJ | 1 |
| Lichtenstein, N; Lustig, N; Spiegelstein-Klarfeld, H | 1 |
| Chen, C; Horecker, BL; Lai, CY | 1 |
| Melcher, G | 1 |
| Voris, L | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Nakahara, M; Yamada, S | 1 |
| Jardetzky, O; Markley, JL; Putter, I | 1 |
| Emrich, J; Inouye, M; Newton, J; Okada, Y; Streisinger, G; Tsugita, A | 1 |
| Abramowitz, A; Bromwell, K; Guroff, G | 1 |
| Honda, I; Kanaoka, M; Naruse, M; Sakakibara, S | 1 |
| Hempel, K; Männl, HF | 1 |
| Andreeva, LA | 1 |
| Makarov, PV | 1 |
| Braams, R | 1 |
| Francis, FJ; Fuleki, T | 1 |
| Alburn, HE; Grant, NH | 1 |
| Kato, T; Makisumi, S; Mitsuyasu, N; Ono, M; Waki, M | 1 |
| Farkas, WR | 1 |
| Arnone, A; Rosa, J; Thillet, J | 1 |
| Wold, F | 1 |
| Kiyama, S; Makita, M; Watanabe, Y; Yamamoto, S | 1 |
| Balashov, SP; Ebrey, TG; Govindjec, R; Imasheva, E; Kono, M; Sheves, M | 1 |
| Akhtaruzzaman, M; Kimura, Y; Takagi, S | 1 |
| Offer, G; Sessions, R | 1 |
| Drapier, D; Gaudriault, S; Girard-Bascou, J; Ketchner, SL; Olive, J; Wollman, FA | 1 |
| Kisters-Woike, B; Müller-Hill, B; Schwamborn, K; Suckow, M; von Wilcken-Bergmann, B | 1 |
| Danielsson, O; Estonius, M; Höög, JO; Jörnvall, H | 1 |
| Balashov, S; Ebrey, T; Govindjee, R; Oesterhelt, D; Sheves, M; Steinberg, G | 1 |
| McDonald, IK; Mitchell, JB; Nandi, CL; Price, SL; Thornton, JM | 1 |
| Geyer, R; Pfeiffer, G; Schmidt, M; Strube, KH | 1 |
| Lah, MS; Ludwig, ML; Palfey, BA; Schreuder, HA | 1 |
| Kagamiyama, H; Mizuno, T; Yano, T | 1 |
| Pishko, EJ; Robertus, JD | 1 |
| Chida, Y; Kikawa, E; Nakazawa, M; Shiono, T; Tamai, M; Wada, Y | 1 |
| Bizouarn, T; Cotton, NP; Diggle, C; Grimley, RI; Jackson, JB; Quirk, PG; Thomas, CM | 1 |
| Ho, C; Ho, NT; Kim, HW; Shen, TJ; Tam, MF; Zou, M | 1 |
| Atkinson, SJ; Butler, GS; Murphy, G; Smith, B; Will, H | 1 |
| Gastmann, U; Häussinger, D; Keul, J; Lehmann, M; Mann, H; Steinacker, JM; Vetter, D | 1 |
| Aikawa, J; Beppu, T; Horinouchi, S; Nishiyama, M; Park, YN | 1 |
| Hitchen, PG; Mullin, NP; Taylor, ME | 1 |
| Eldin, S; Knight, KL; Logan, KM; Skiba, MC | 1 |
| Hodges, RS; Tripet, B; Vale, RD | 1 |
| Ahn, J; Kraynov, VS; Lee, H; Tsai, MD; Werneburg, BG; Zhong, X | 1 |
| Dabrosin, C; Hallström, A; Hammar, M; Ungerstedt, U | 1 |
| Burnol, AF; Girard, J; Kasus-Jacobi, A; Perdereau, D; Tartare-Deckert, S; Van Obberghen, E | 1 |
| Chen, JG; Rudnick, G; Sachpatzidis, A | 1 |
| Akanuma, M; Harada, H; Hiroi, S; Katsushika, S; Kimura, A; Nakamura, H; Ohsuzu, F; Satoh, M | 1 |
| Aldrich, HC; Ferry, JG; Maupin-Furlow, JA | 1 |
| Bakker, AH; Belin, D; Blatter, MC; Grimbergen, JM; Lansink, M; Quax, PH; van Hinsbergh, VW; Verheijen, JH | 1 |
| Ekberg, M; Nordlund, P; Pötsch, S; Sahlin, M; Sandin, E; Sjöberg, BM; Thunnissen, M | 1 |
| Godart, C; Préhu, C; Vigneron, C; Wajcman, H | 1 |
| Debus, RJ; Hays, AM; Hundelt, M; Junge, W | 1 |
| Feng, YH; Husain, A; Karnik, SS; Miura, S | 1 |
| Munagala, NR; Wang, CC | 1 |
| Ameglio, F; Biolcati, G; D'Amato, M; Griso, D; Macrí, A | 1 |
| Jorgensen, PL; Nielsen, JM; Pedersen, PA; Rasmussen, JH | 1 |
| Bartolucci, S; Cannio, R; Giordano, A; La Cara, F; Raia, CA; Rossi, M | 1 |
| Argüello, JM; Cheung, MC; Lingrel, JB; Whitis, J | 1 |
| Connolly, BA; Evans, SJ; Maughan, WN; Shipstone, EJ | 1 |
| Blanco, L; Gutiérrez, C; Illana, B; Lázaro, JM; Meijer, WJ; Salas, M | 1 |
| Andreu, AL; Bruno, C; Cervera, C; DiMauro, S; Gamez, J; Navarro, C; Shanske, S; Tamburino, L | 1 |
| Karam, J; Konigsberg, WH; Lin, T; Yang, G | 1 |
| Furet, P; García-Echeverría, C; Gay, B; Rahuel, J; Schoepfer, J; Zeller, M | 1 |
| Grove, JR; Hart, CP; Keval, AA; Martin, JE; Northrop, JP; Patel, DV; Pustelnik, MJ; Reed, MA | 1 |
| Nishiyama, T; Uchida, M; Yamaguchi, H | 1 |
| Dwyer, TM; Frerman, F; Marrugo, F; Muller, M; Zhang, L | 1 |
| Guan, Y; Lepock, JR; Leveque, V; Nick, HS; Ramilo, CA; Silverman, DN; Tainer, JA | 1 |
| Arora, KK; Catt, KJ; Chung, HO; Yang, Q | 1 |
| Koopman, J; Lounes, KC; Soria, C; Soria, J; Turchini, MF; Valognes, A | 1 |
| Erhardt, A; Hassan, M; Häussinger, D; Niederau, C; Osman, Y | 1 |
| Choi, G; Choi, KY; Ha, NC; Kim, DH; Kim, SW; Oh, BH; Park, S | 1 |
| Lacount, MW; Lebioda, L; Lewinski, K; Ortlund, E | 1 |
| Meunier, JC; Moisand, C; Mollereau, C; Mouledous, L; Topham, CM | 1 |
| DiMarco, M; Gagnon, L; Kirby, R; Penney, CL; Zacharie, B | 1 |
| Barbolina, MV; Demidkina, TV; Faleev, NG; Gollnick, PD; Phillips, RS | 1 |
| Iffland, A; Johnsson, K; Saudan, C; Tafelmeyer, P | 1 |
| Aung, HP; Bocola, M; Röhm, KH; Schleper, S | 1 |
| Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW | 1 |
| Fukuda, R; Nagai, M; Okishio, N; Tanaka, T | 2 |
| Agrawal, A; Greenhough, TJ; Shrive, AK; Volanakis, JE | 1 |
| Babolat, M; Deville-Bonne, D; Janin, J; Schneider, B; Véron, M; Xu, YW | 1 |
| Eisenberg, D; Gill, HS | 1 |
| Krogh, BO; Shuman, S | 1 |
| Aeschliman, SM; Ballou, DP; Massey, V; Ortiz-Maldonado, M | 1 |
| Brochon, JC; Cunin, R; Fetler, L; Hervé, G; Tauc, P | 1 |
| Acquaviva, C; Aydin, A; Benoist, JF; Callebaut, I; Elion, J; Guffon, N; Ogier de Baulny, H; Porquet, D; Touati, G | 1 |
| Malek, TR; Olosz, F | 1 |
| Carenbauer, AL; Crowder, MW; Garrity, JD; Periyannan, G; Yates, RB | 1 |
| Funahashi, J; Takano, K; Yamagata, Y; Yutani, K | 1 |
| Duprex, WP; Erlenhöfer, C; Rima, BK; Schneider-Schaulies, J; Ter Meulen, V | 1 |
| Bayne, M; Coates, E; Monsma, FJ; Morse, KL; Murgolo, NJ; Shin, N; Strader, CD | 1 |
| Morlock, G; Poppe, L; Rétey, J; Röther, D; Viergutz, S | 1 |
| Acharya, N; Handa, P; Varshney, U | 1 |
| Berrin, JG; Flatman, R; Juge, N; Roepstorff, P; Roussel, A; Tahir, TA; Williamson, G | 1 |
| Schwalbe, RA; Wingo, CS; Xia, SL | 1 |
| Kinoshita, E; Maejima, H; Seyama, I; Yamaoka, K | 1 |
| Murray, TA; Swenson, RP | 1 |
| Escrieut, C; Fourmy, D; Galés, C; Maigret, B; Martinez, J; Moroder, L; Poirot, M; Pradayrol, L; Silvente-Poirot, S; Taillefer, J | 1 |
| Aldred, S; Fitzgerald, M; Moore, KM; Waring, RH | 1 |
| Angsuthanasombat, C; Kanintronkul, Y; Katzenmeier, G; Panyim, S; Sramala, I | 1 |
| Bergo, V; Rothschild, KJ; Spudich, EN; Spudich, JL | 1 |
| Bösl, B; Narayanan, S; Reif, B; Walter, S | 1 |
| Blouquit, Y; Faraggi, M; Houée-Levin, C; Jollès, P; Sicard-Roselli, C; Stuart-Audette, M | 1 |
| WOLLENWEBER, P | 1 |
| DECONNINCK, G; VOETS, JP | 1 |
| GUROFF, G; ITO, T | 2 |
| NOZAKI, Y; TANFORD, C | 1 |
| BRAUN, L | 1 |
| LORINCZ, AB; RYAN, WL | 1 |
| Breuer, LH; Loosli, JK; Pond, WG; Warner, RG | 1 |
| DELALLOSA, P; JUTISZ, M; TERTRIN, C | 1 |
| GERIFFIN, G; KESNER, L; MUNTWYLER, E | 1 |
| PATAKI, G | 1 |
| OLSON, JC; PUNCH, JD; SCALETTI, JV | 1 |
| BERNFIELD, MR; BRIMACOMBE, RL; LEDER, P; NIRENBERG, MW; ROTTMAN, FM; TRUPIN, JS | 1 |
| ROTHSTEIN, M | 1 |
| Blotta, I; Bruni, AC; Campeggi, LM; Cantafora, A; Confaloni, A; Crestini, A; Di Natale, M; Forloni, G; Franceschi, M; Frigerio, CS; Maletta, R; Marcon, G; Perri, M; Piscopo, P; Terreni, L | 1 |
| Chen, N; Li, B; Murphy, TH; Raymond, LA | 1 |
| Fu, G; Hamasaki, N; Jiang, X; Lv, F; Shi, C; Tian, L; Wang, T; Yang, B; Yu, W | 1 |
| Balashova, N; Beuve, A; Chang, FJ; Lamothe, M; Shirokov, R | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Ishiyama, N; Lin, T; Lipkowitz, S; Park, M; Peschard, P | 1 |
| Craik, CS; Fletterick, RJ; Ruggles, SW | 1 |
| Balakrishnan, G; Case, MA; McLendon, GL; Pevsner, A; Spiro, TG; Tengroth, C; Zhao, X | 1 |
| Ahgrén, A; Aspenström, P; Chiara, F; Forsberg, H; Goumans, MJ; Heldin, CH; Hellberg, C; Heuchel, R; Rasola, A; Wernstedt, C | 1 |
| Alleva, DG; Nickolls, SA; Ott, TR; Pahuja, A; Struthers, RS | 1 |
| Hattori, S; Kowa, H; Nakashima, K; Sakuma, K; Shimoda, M; Urakami, K; Wada, K; Wakutani, Y | 1 |
| Adachi, M; Hirata, A; Mikami, B; Utsumi, S | 1 |
| Goto, T; Kato, N; Omata, M | 1 |
| Bjornsti, MA; Burgin, AB; Colley, WC; van der Merwe, M; Vance, JR | 1 |
| Argüello, JM; Kertesz, TM; Mandal, AK; Yang, Y | 1 |
| Morrison, CJ; Overall, CM; Pelman, GR | 1 |
| Brown, DE; Dooley, DM; Knowles, PF; Kurtis, CR; McPherson, MJ; Mure, M; Phillips, SE; Rogers, MS; Saysell, C; Tambyrajah, WS; Wilmot, CM | 1 |
| Gupta, A; Lewis, F; Mao, Q; Unadkat, JD; Vethanayagam, RR; Wang, H; Zhang, Y | 1 |
| de Jong, RM; Dijkstra, BW; Fraaije, MW; Janssen, DB; Tang, L; Torres Pazmiño, DE | 1 |
| Agarwal, R; Binz, T; Swaminathan, S | 1 |
| di Tiani, M; Fanelli, F; Favre, N; Missotten, M; Nichols, A; Rommel, C; Scheer, A; Wilson, J | 1 |
| Caflisch, A; Gorfe, AA | 1 |
| Hoef-Emden, K; Melkonian, M; Tran, HD | 1 |
| Meyer, RD; Mohammadi, M; Rahimi, N | 1 |
| Becker, JM; Lee, YH; Naider, F | 1 |
| Almazan, F; Chen, Y; Green, SR; Quehenberger, O | 1 |
| Jewhurst, SA; Robertson, NB; Waite, JH; Zhao, H | 1 |
| Cuff, AL; Janes, RW; Martin, AC | 1 |
| Bazhulina, NP; Demidkina, TV; Faleev, NG; Gollnick, PD; Kulikova, VV; Papisova, AI; Phillips, RS | 1 |
| Grid, D; Lagrange, E; Magdelaine, C; Magy, L; Sturtz, F; Tazir, M; Vallat, JM | 1 |
| Heinz, DW; Schubert, WD; Wollert, T | 1 |
| Almeida, FC; Da Poian, AT; Juliano, L; Juliano, MA; Lima, CS; Sarzedas, CG; Valente, AP | 1 |
| Cane, DE; Christianson, DW; Jiang, J; Vedula, LS; Zakharian, T | 1 |
| Bosak, A; Gazić, I; Kovarik, Z; Vinković, V | 1 |
| Beye, M; Hasselmann, M; Koeniger, G; Koeniger, N; Pflugfelder, J; Tingek, S; Vekemans, X | 1 |
| Bhavani, BS; Bisht, S; Murthy, MR; Pai, VR; Rajaram, V; Rao, NA; Savithri, HS | 1 |
| Holyavka, MG; Kovaleva, TA; Kozhedub, SV; Rezvan, SG | 1 |
| Chang, YH; Chiu, CC; Chuang, LY; Hwang, CC; Wang, CZ | 1 |
| Benfield, AP; Clements, JH; DeLorbe, JE; Martin, SF; Millspaugh, LE; Plake, HR; Teresk, MG | 1 |
| Ellenberger, T; McClendon, TB; Niedernhofer, LJ; Orelli, B; Schärer, OD; Tsodikov, OV | 1 |
| Budyak, IL; Büldt, G; Engelhard, M; Heberle, J; Hoomann, T; Kim, YJ; Labahn, J; Radu, I; Schlesinger, R | 1 |
| Aye, SL; Loprasert, S; Prapagdee, B; Rangkadilok, N; Ruchirawat, S; Sallabhan, R; Thasana, N | 1 |
| Alzualde, A; Atares, B; Barandiaran, M; Calero, M; Estanga, A; Ferrer, I; Gorostidi, A; Indakoetxea, B; Juste, R; López de Munain, A; Moreno, F; Rodriguez-Martínez, AB; Ruiz, I; van Leeuwen, FW | 1 |
| Baldet, P; Bertrand, A; Boulila Zoghlami, L; Brouquisse, R; Cabasson, C; Chaïbi, W; Deborde, C; Djebali, W; Gallusci, P; Hédiji, H; Maucourt, M; Moing, A | 1 |
| Culka, A; Edwards, HG; Jehlička, J | 1 |
| Gray, VE; Kumar, S | 1 |
| Castillo, O; De Sáez Ruiz, A; Marchi, R; Meyer, M; Rojas, H; Weisel, JW | 1 |
| Bau, AE; de Zwart-Storm, EA; Foelster-Holst, R; Frank, J; Graziadio, C; Kamps, MA; Martin, PE; Paskulin, GA; Rosa, RF; van Geel, M; van Steensel, MA; Zen, PR | 1 |
| Acevedo-Arozena, A; Alqatari, M; Banks, GT; Bannerman, D; Brandner, S; Deacon, R; Fainzilber, M; Fisher, EM; Greensmith, L; Groves, M; Haas, MA; Hafezparast, M; Kalmar, B; Koltzenburg, M; Kuta, A; Line, S; Parkinson, N; Philpott, A; Rishal, I; Shepherd, HL; Stewart, S | 1 |
| Bell, MJ; Chang, KM; Cisneros, GA; Dewage, SW; Fatma, S; Hendrickson, TL; Joshi, N; Silva, G; Zhao, L | 1 |
| Chen, JH; Huang, ZR; Liu, HY; Zhu, SJ | 1 |
| Buranaprapuk, A; Liwporncharoenvong, T; Malaikaew, P; Yenjai, S | 1 |
| Guo, W; Liang, Y; Peng, J; Shen, Q; Yang, X | 1 |
| Berlot, CH; Bünemann, M; Hein, P; Hoffmann, C; Lohse, MJ; Nuber, S; Winkler, C; Zabel, U; Ziegler, N | 1 |
| Chen, CH; Chen, WT; Chen, YW; Cheng, CS; Luo, YC; Lyu, PC; Yin, HS | 1 |
| Buragohain, AK; Dutta, M; Ray, SK; Satapathy, SS | 1 |
| Guo, Y; Li, YT; Liu, RM; Rao, FF; Si, MZ; Tang, WY; Xiong, Y; Zhang, JM | 1 |
| Alessandri, JL; Arnaud, E; Balu, M; Collet, C; Daire, VC; Di Rocco, F | 1 |
| Bucher, M; Chen, F; Darbre, T; Gerber, S; Lizak, C; Locher, KP; Michaud, G; Reymond, JL; Schubert, M; Zenobi, R; Zinne, D | 1 |
| Cho, SJ; Kirubakaran, P; Kothandan, G; Muthusamy, K | 1 |
| Cascarina, SM; Flores, N; Gonzalez Nelson, AC; Paul, KR; Petri, M; Rogge, RA; Ross, ED | 1 |
| Gao, J; Guo, Y; Niu, F; Qiu, C; Sun, Y; Tang, W; Wen, H; Ye, L; Yi, X; Yu, S; Zhang, Z | 1 |
| Angelaccio, S; Angelucci, F; Contestabile, R; Ilari, A; Morea, V; Saccoccia, F | 1 |
| Fan, CZ; Li, YT; Pan, ZF; Tang, WY; Wang, W | 1 |
| Ide, M; Irie, M; Kamikawa, T; Kashiwagi, H; Miura, T; Morikami, K; Muraoka, T; Nakamura, M; Nishihara, M | 1 |
| Katahira, M; Kondo, K; Mikami, B; Nagata, T; Saka, N; Wan Osman, WH | 1 |
| Atlasi, Y; Ehrenhofer-Murray, AE; Kelly, VP; Legrand, C; Lyko, F; Müller, M; Tuorto, F | 1 |
| Dong, Z; Jiang, P; Li, D; Li, G; Li, L; Wu, J | 1 |
| Adachi, S; Anai, H; Hanada, K; Ishizaki, T; Kawano, M; Matsuoka, S; Nishida, M; Nishida, Y; Okuma, T; Tanaka, K; Terabayashi, T; Tomo, T; Tsumura, H | 1 |
| Fischer, M; Görlich, D; Huyton, T; Jaiswal, M; Taxer, W | 1 |
| Colombo Pimentel, T; de Sousa Fontes, VM; Dos Santos Lima, M; Magnani, M; Martins da Silva, AB; Suely Madruga, M | 1 |
5 review(s) available for tyrosine and asparagine
| Article | Year |
|---|---|
Synthetic analogs of oxytocin and the vasopressins.
Topics: Amino Acids; Animals; Anura; Asparagine; Cystine; Hypothalamus; In Vitro Techniques; Oxytocin; Peptide Chain Termination, Translational; Peptides; Phenylalanine; Proline; Rats; Receptors, Drug; Structure-Activity Relationship; Tyrosine; Vasopressins | 1973 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
[YMDD motif and its significance].
Topics: Amino Acid Motifs; Asparagine; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Methionine; Mutation; Reverse Transcriptase Inhibitors; Reverse Transcription; RNA-Directed DNA Polymerase; Tyrosine | 2004 |
1 trial(s) available for tyrosine and asparagine
| Article | Year |
|---|---|
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1987 |
253 other study(ies) available for tyrosine and asparagine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Transfer RNA in aging Drosophila: II. Isoacceptor patterns.
Topics: Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Drosophila melanogaster; Histidine; Leucine; Male; RNA, Transfer; Tyrosine | 1979 |
The free amino acid pool composition during growth of the culture of Xanthomonas citri (Hasse) Dowson.
Topics: Alanine; Amino Acids; Asparagine; Kinetics; Threonine; Tyrosine; Xanthomonas | 1979 |
Alterations in SVT2 cell transfer RNAs in response to cell density and serum type.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Cell Line; Cell Transformation, Neoplastic; Culture Media; Cyanogen Bromide; Histidine; Mice; Mice, Inbred BALB C; RNA, Transfer; RNA, Viral; Simian virus 40; Tyrosine | 1975 |
Tyrocidine synthetase system.
Topics: Aminoacylation; Asparagine; Bacillus; Cell Division; Chromatography, DEAE-Cellulose; Glutamine; Leucine; Ligases; Methods; Molecular Weight; Multienzyme Complexes; Ornithine; Phenylalanine; Proline; Time Factors; Tyrocidine; Tyrosine; Tyrothricin; Valine | 1975 |
Relation of cell type and cell density in tissue culture to the isoaccepting spectra of the nucleoside Q containing tRNAs: tRNATyr, tRNAHis, tRNAAsn and tRNAAsp.
Topics: Asparagine; Aspartic Acid; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Cyanogen Bromide; Guanosine; Histidine; RNA, Transfer; Simian virus 40; Tyrosine | 1978 |
Amino acid sequence of the first hypervariable region of 2 kappa and 2 lambda Bence Jones cryoglobulin.
Topics: Amino Acid Sequence; Asparagine; Bence Jones Protein; Binding Sites, Antibody; Cryoglobulins; Humans; Immunoglobulin kappa-Chains; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Tyrosine | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine.
Topics: Anticodon; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Escherichia coli; Guanosine; Histidine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Protons; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Tyrosine | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Synthesis of peptides by fragment condensation on a solid support. II. A scheme for preparation of 4,8-disubstituted vasopressins evaluated on 8-arginine-vasopressin.
Topics: Arginine Vasopressin; Asparagine; Cysteine; Peptide Fragments; Peptides; Phenylalanine; Proline; Tyrosine; Vasopressins | 1976 |
Studies on trypsin inhibitors. Part III. Synthesis of the protected decapeptide (sequence 15-24) of porcine pancreatic secretory trypsin inhibitor II (Kazal).
Topics: Animals; Asparagine; Aspartic Acid; Cysteine; Glycine; Isoleucine; Peptides; Proline; Swine; Threonine; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine; Valine | 1976 |
Computer modeling studies on the subsite interactions of ribonuclease T1.
Topics: Asparagine; Binding Sites; Computer Simulation; Dinucleoside Phosphates; Exoribonucleases; Guanosine Diphosphate; Guanosine Monophosphate; Tyrosine | 1992 |
T41 mutation in lac repressor is Tyr282----Asp.
Topics: Asparagine; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Mutation; Repressor Proteins; Tyrosine | 1992 |
Activation of insulin receptor signaling by a single amino acid substitution in the transmembrane domain.
Topics: Animals; Asparagine; Base Sequence; Biological Transport; Cell Division; CHO Cells; Cricetinae; DNA; Enzyme Activation; Glucose; Humans; Insulin; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Signal Transduction; Transfection; Tyrosine; Valine | 1992 |
Occurrence of a Tyr393----Asn (Y393N) mutation in the E1 alpha gene of the branched-chain alpha-keto acid dehydrogenase complex in maple syrup urine disease patients from a Mennonite population.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alleles; Asparagine; Base Sequence; Blotting, Southern; DNA; Ethnicity; Genes; Humans; Ketone Oxidoreductases; Maple Syrup Urine Disease; Molecular Sequence Data; Multienzyme Complexes; Mutation; Oligonucleotide Probes; Philadelphia; Polymerase Chain Reaction; Tyrosine | 1991 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Function of the fully conserved residues Asp99, Tyr52 and Tyr73 in phospholipase A2.
Topics: Asparagine; Base Sequence; Binding Sites; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipases A; Phospholipases A2; Protein Engineering; Substrate Specificity; Tyrosine | 1990 |
Vibrational spectroscopy of bacteriorhodopsin mutants: evidence for the interaction of proline-186 with the retinylidene chromophore.
Topics: Amino Acid Sequence; Asparagine; Bacteriorhodopsins; Fourier Analysis; Molecular Sequence Data; Mutation; Photochemistry; Proline; Protein Conformation; Protons; Retinal Pigments; Schiff Bases; Spectrophotometry, Infrared; Spectrum Analysis; Tyrosine; Valine; Vibration | 1990 |
Hemoglobin Saint Mandé [beta 102 (G4) Asn----Tyr]. Functional studies and structural modeling reveal an altered T state.
Topics: Asparagine; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Molecular Structure; Mutation; Oxygen; Tyrosine | 1990 |
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry, Physical; Glutamates; Glutamine; Histidine; Mathematics; Models, Molecular; Phenylalanine; Ribonuclease, Pancreatic; Sulfates; Tyrosine; X-Ray Diffraction | 1989 |
cDNA cloning of the E1 alpha subunit of the branched-chain alpha-keto acid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alleles; Animals; Asparagine; Cloning, Molecular; DNA; Fibroblasts; Gene Library; Humans; Immunoblotting; Ketone Oxidoreductases; Liver; Maple Syrup Urine Disease; Multienzyme Complexes; Mutation; Rats; Tyrosine | 1989 |
Rab 12 kD.
Topics: Amino Acid Sequence; Animals; Asparagine; beta 2-Microglobulin; Humans; Rabbits; Sequence Homology, Nucleic Acid; Serum Amyloid A Protein; Tryptophan; Tyrosine | 1989 |
Saturation mutagenesis of a major histocompatibility complex protein domain: identification of a single conserved amino acid important for allorecognition.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Cloning, Molecular; Escherichia coli; Genes, MHC Class I; H-2 Antigens; Histocompatibility Antigen H-2D; HLA Antigens; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Conformation; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tyrosine | 1988 |
OF4949, new inhibitors of aminopeptidase B. III. Biosynthesis.
Topics: Aminopeptidases; Asparagine; Carbon Radioisotopes; Penicillium; Peptides, Cyclic; Tyrosine | 1986 |
The structure of insulin in relation to its immunological activity.
Topics: Alanine; Animals; Antibody Specificity; Asparagine; Binding Sites; Cross Reactions; Epitopes; Guinea Pigs; Insulin; Insulin Antibodies; Iodine; Nitro Compounds; Proinsulin; Protein Conformation; Structure-Activity Relationship; Tyrosine | 1971 |
[Effect of specific amino acids on the hot-bath-test in multiple sclerosis patients].
Topics: Amino Acids; Asparagine; Body Temperature; Epinephrine; Female; Flicker Fusion; Glutamine; Humans; Male; Multiple Sclerosis; Neurotransmitter Agents; Norepinephrine; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine | 1973 |
Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies.
Topics: Aconitic Acid; Alanine; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Asparagine; Aspartic Acid; Autoanalysis; Chromatography, Gel; Electrophoresis, Paper; Glutamates; Glycine; Hydrolysis; Immunoglobulin Fragments; Rabbits; Serine; Streptococcus pneumoniae; Threonine; Tyrosine; Valine | 1974 |
Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus.
Topics: Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Drosophila melanogaster; Genes; Histidine; Metamorphosis, Biological; Models, Biological; Mutation; Oligonucleotides; Ribonucleotides; RNA, Transfer; Spectrophotometry, Ultraviolet; Transcription, Genetic; Tritium; Tyrosine | 1973 |
[Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)].
Topics: Alanine; Animals; Asparagine; Dihydrolipoamide Dehydrogenase; Electron Transport; Glutamate Dehydrogenase; Glutamates; Glycine; Histocytochemistry; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1974 |
The action of trypsin and of chymotrypsin on phenylthiocarbamyl-angiotensin II.
Topics: Angiotensin II; Animals; Arginine; Asparagine; Blood Pressure; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Dogs; Electrophoresis; Sulfur Isotopes; Trypsin; Tyrosine; Valine | 1967 |
Differences in the transfer RNA's of normal liver and Novikoff hepatoma.
Topics: Amino Acids; Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Ligases; Liver; Liver Neoplasms; Methods; Neoplasms, Experimental; Rats; RNA, Transfer; Tritium; Tyrosine | 1969 |
Alterations in specific transfer ribonucleic acids in a spectrum of hepatomas.
Topics: Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Diploidy; Escherichia coli; Genetic Code; Hindlimb; Histidine; Ligases; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Phenylalanine; Polynucleotides; Polyploidy; Rats; Ribosomes; RNA, Transfer; Tritium; Tyrosine; Ultracentrifugation | 1971 |
Electron transfer reactions in biological systems: the reduction of ferricytochrome c by chromous ions.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Asparagine; Autoradiography; Chromatography, Gel; Chromium; Chromium Radioisotopes; Cytochrome c Group; Electron Transport; Horses; Hydrolysis; In Vitro Techniques; Myocardium; Oxidation-Reduction; Peptides; Protein Binding; Protein Conformation; Structure-Activity Relationship; Trypsin; Tyrosine | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Purification, properties, and identity of liver mitochondrial tyrosine aminotransferase.
Topics: Amino Acids; Animals; Antibodies; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Crystallization; Cysteine; Cytoplasm; Diffusion; Dihydroxyphenylalanine; Fenclonine; Glutamates; Isoelectric Focusing; Isoenzymes; Ketoglutaric Acids; Male; Methionine; Mitochondria, Liver; Molecular Weight; Monoiodotyrosine; Oxaloacetates; Phenylpyruvic Acids; Rats; Stereoisomerism; Tryptophan; Tyrosine; Tyrosine Transaminase; Ultracentrifugation; Vibration | 1971 |
High-resolution proton NMR studies of low affinity hemoglobins.
Topics: Asparagine; Aspartic Acid; Binding Sites; Carbon Isotopes; Deuterium; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Iron; Japan; Kansas; Magnetic Resonance Spectroscopy; Methylation; Mutation; Oxyhemoglobins; Protein Binding; Protein Conformation; Threonine; Tyrosine | 1973 |
Substrate binding and intersubunit interactions in L-asparaginase.
Topics: Acetylation; Amino Acids; Asparaginase; Asparagine; Binding Sites; Drug Stability; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Ligands; Macromolecular Substances; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Tyrosine; Ultracentrifugation; Urea | 1974 |
In vitro assembly of L-asparaginase subunits.
Topics: Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Macromolecular Substances; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Time Factors; Tryptophan; Tyrosine; Ultracentrifugation; Urea | 1974 |
[Studies on L-asparaginase, inactivation and modification of the enzyme by N-bromosuccinimide and substrate specificity of the reaction (author's transl)].
Topics: Amino Acids; Asparaginase; Asparagine; Bromine; Buffers; Chromatography, Gas; Dialysis; Electrophoresis, Paper; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Ninhydrin; Peptides; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Succinimides; Temperature; Tyrosine; Ultracentrifugation | 1974 |
Amino acids and peptides. 34. Synthesis of a structure related to scotophobin.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartic Acid; Glutamine; Glycine; Lysine; Memory; Peptides; Serine; Tyrosine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
[Isolation and characterization of glycopeptides from pig aorta. I].
Topics: Acetates; Aminopeptidases; Animals; Aorta; Asparagine; Autoanalysis; Binding Sites; Chromatography, Ion Exchange; Electrophoresis, Paper; Fucose; Galactose; Glucosamine; Glycopeptides; Mannose; Neuraminic Acids; Neuraminidase; Pronase; Protein Binding; Swine; Tyrosine | 1972 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.
Topics: Alkylation; Amino Acids; Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Deoxyribonucleases; Disulfides; Histidine; Methane; Nitro Compounds; Pancreas; Peptides; Tyrosine | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Characterization and mating reactions of clinical isolates of Trychophyton mentagrophytes and T. rubrum which produce a diffusible brownish pigment.
Topics: Agar; Ascomycota; Asparagine; Conjugation, Genetic; Culture Media; Hair; Humans; Keratins; Phenylalanine; Pigments, Biological; Quinic Acid; Shikimic Acid; Stereoisomerism; Tinea; Trichophyton; Tyrosine; Urease | 1974 |
Highly restricted specificity of the serine proteinase aspergillopeptidase B.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspergillus; Cattle; Chromatography, Ion Exchange; Evaluation Studies as Topic; Glutamates; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Methods; Oxidation-Reduction; Peptide Fragments; Peptide Hydrolases; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tyrosine; Zinc | 1974 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Substrate specificity of elastolytic and nonelastolytic proteinases from Pseudomonas aeruginosa.
Topics: Arginine; Asparagine; Chromatography; Glutamates; Glycine; Insulin; Lysine; Pancreatic Elastase; Peptide Hydrolases; Peptides; Phenylalanine; Pseudomonas aeruginosa; Sulfonic Acids; Tyrosine | 1966 |
Regional and subcellular distribution of aminotransferases in rat brain.
Topics: Alanine; Alanine Transaminase; Aminobutyrates; Animals; Asparagine; Aspartate Aminotransferases; Brain; Cerebral Cortex; Corpus Callosum; Glutamates; Glutamine; Glyoxylates; Ketoglutaric Acids; Male; Mesencephalon; Methionine; Ornithine; Oxaloacetates; Phenylalanine; Rats; Sciatic Nerve; Spinal Cord; Subcellular Fractions; Transaminases; Tyrosine | 1972 |
Characterization of a Trichophyton mentagrophytes and its diffusible pigment.
Topics: Agar; Asparagine; Chemical Phenomena; Chemistry; Chromatography, Gel; Culture Media; Electrophoresis, Paper; Glucose; Hair; Indoles; Molecular Weight; Pigments, Biological; Quinones; Spectrophotometry; Trichophyton; Tyrosine; Urea | 1972 |
Crystal structure of a subtilisin BPN' complex with N-benzoyl-L-arginine.
Topics: Amides; Arginine; Asparagine; Bacillus; Benzoates; Binding Sites; Carboxylic Acids; Crystallography; Esters; Guanidines; Ketones; Models, Structural; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Peptide Hydrolases; Protease Inhibitors; Protein Conformation; Serine; Tyrosine; X-Ray Diffraction | 1972 |
Transamination of amino acids in homogenates of rat brzain.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Asparagine; Aspartic Acid; Brain; Chromatography; Culture Media; Electrophoresis, Paper; Glutamates; Glutamine; Isoleucine; Ketoglutaric Acids; Male; Methionine; Organ Culture Techniques; Ornithine; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1971 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Immunosuppressive effects of L-asparaginase.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine | 1970 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Phenylalanine uptake and phenylalanine-binding material in Comamonas sp. (ATCC 11299a).
Topics: Asparagine; Bacteria; Biological Transport; Carbon Isotopes; Depression, Chemical; Dialysis; Dinitrophenols; Enzyme Induction; Ethylmaleimide; Filtration; Kinetics; Malonates; Osmolar Concentration; Phenylalanine; Protein Biosynthesis; Tryptophan; Tyrosine | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
Gas-liquid chromatography and mass spectrometry of deuterium-containing amino acids as their trimethylsilyl derivatives.
Topics: Alanine; Amino Acids; Asparagine; Chromatography, Gas; Deuterium; Glycine; Leucine; Methionine; Proline; Silicon; Spectrum Analysis; Tyrosine; Valine | 1970 |
Effect of carbobenzoxy derivatives of amino acids on glutamine synthesis and gamma-glutamyl transfer.
Topics: Acyltransferases; Alanine; Amino Acids; Animals; Asparagine; Brain; Chemical Phenomena; Chemistry; Formates; Glutamine; Glycine; Kinetics; Ligases; Liver; Lysine; Phenylalanine; Rats; Sheep; Tyrosine | 1970 |
Primary structure of two COOH-terminal hexapeptides from rabbit muscle aldolase: a difference in the structure of the alpha and beta subunits.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Carboxypeptidases; Chromatography, Ion Exchange; Chymotrypsin; Fructose-Bisphosphate Aldolase; Histidine; Muscles; Rabbits; Trypsin; Tyrosine | 1970 |
A new hypothesis on the evolution of the genetic code.
Topics: Amino Acids; Arginine; Asparagine; Biological Evolution; Cysteine; Genetic Code; Glutamine; Leucine; Lysine; Methionine; Models, Chemical; Models, Structural; Nucleotides; Proline; Serine; Threonine; Tyrosine | 1970 |
Energy metabolism of proteins and amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Temperature Regulation; Caseins; Dietary Proteins; Gelatin; Glutamates; Glycine; Humans; Leucine; Muscles; Nutritional Physiological Phenomena; Proteins; Rats; Tyrosine | 1971 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine | 1968 |
Frame shift mutations near the beginning of the lysozyme gene of bacteriophage T4.
Topics: Amino Acid Sequence; Asparagine; Chromatography, Ion Exchange; Chromatography, Paper; Coliphages; Genes; Genetic Code; Genetics, Microbial; Glutamates; Muramidase; Mutation; Peptides; Trypsin; Tyrosine | 1968 |
Mode of action of p-chlorophenylalanine on Pseudomonas species (11299a).
Topics: Amino Acids; Asparagine; Bacterial Proteins; Biological Transport; Carbon Isotopes; Cell-Free System; Culture Media; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Tyrosine | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
The conversion of [3H]tyrosine to [3H]DOPA in mouse melanoma in vivo.
Topics: Animals; Asparagine; Aspartic Acid; Chromatography, Paper; Dihydroxyphenylalanine; Electrophoresis; Glutamates; Glutamine; Melanoma; Mice; Neoplasms, Experimental; Tyrosine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
[An attempt at the use of autoradiography for the study of the chemical composition of cellular structures (experiments using the oocytes of the frog)].
Topics: Adenine; Amino Acids; Animals; Anura; Asparagine; Autoradiography; Carbon Isotopes; Female; Glutamates; Glycine; Histocytochemistry; Leucine; Methionine; Methods; Nucleosides; Ovum; Phenylalanine; Tritium; Tyrosine | 1966 |
Rate constants of hydrated electron reactions with peptides and proteins.
Topics: Alanine; Albumins; Asparagine; Electrons; Gelatin; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Muramidase; Peptides; Phenylalanine; Proline; Proteins; Ribonucleases; Tryptophan; Tyrosine; Valine | 1967 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Reactions in frozen systems. VI. Ice as a possible model for biological structured-water systems.
Topics: Acetylcholine; Asparagine; Catalysis; Chemical Phenomena; Chemistry; Copper; Cytosine; Dioxins; Glutamates; Glutamine; Glycine; Hydroxylamines; Ice; Imidazoles; Kinetics; Models, Theoretical; Nitrates; Phenylalanine; Piperazines; Potassium Chloride; Pyrazoles; Serine; Tyrosine | 1967 |
Ribonuclease T1 peptides. I. Synthesis of a protected N-terminal undecapeptide containing asparagine residue in third position.
Topics: Asparagine; Azides; Ribonucleases; Tyrosine | 1967 |
Effect of diet on the queuosine family of tRNAs of germ-free mice.
Topics: Animals; Anticodon; Asparagine; Aspartic Acid; Codon; Diet; Female; Germ-Free Life; Guanosine; Histidine; Male; Mice; Nucleoside Q; RNA, Transfer; Tyrosine | 1980 |
The structure of hemoglobin Creteil (beta 89 Ser replaced by Asn) is similar to that of abnormal human hemoglobins having sequence changes at Tyr 145 beta.
Topics: Amino Acid Sequence; Asparagine; Hemoglobins, Abnormal; Heterozygote; Humans; Models, Molecular; Protein Conformation; Serine; Spectrophotometry; Tyrosine; X-Ray Diffraction | 1981 |
Practical gas-liquid chromatographic method for the determination of amino acids in human serum.
Topics: Amino Acids; Arginine; Asparagine; Chromatography, Gas; Formates; Formic Acid Esters; Glutamine; Humans; Isoleucine; Leucine; Tyrosine | 1982 |
Effects of substitution of tyrosine 57 with asparagine and phenylalanine on the properties of bacteriorhodopsin.
Topics: Asparagine; Bacteriorhodopsins; Cold Temperature; Darkness; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Light; Phenylalanine; Photochemistry; Protons; Spectrophotometry, Ultraviolet; Tyrosine | 1995 |
Purification and characterization of a CM-glycinin digesting protease from soybean seeds.
Topics: Alanine; Amino Acid Sequence; Asparagine; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Globulins; Glycine max; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Molecular Sequence Data; Molecular Weight; Plant Proteins, Dietary; Seeds; Soybean Proteins; Tyrosine | 1993 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Chloroplasts can accommodate inclusion bodies. Evidence from a mutant of Chlamydomonas reinhardtii defective in the assembly of the chloroplast ATP synthase.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Centrifugation, Density Gradient; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Crosses, Genetic; Genes, Fungal; Immunohistochemistry; Inclusion Bodies; Isoleucine; Macromolecular Substances; Molecular Sequence Data; Phenotype; Point Mutation; Proton-Translocating ATPases; Restriction Mapping; Tyrosine | 1995 |
Replacement of invariant bZip residues within the basic region of the yeast transcriptional activator GCN4 can change its DNA binding specificity.
Topics: Amino Acid Sequence; Arginine; Asparagine; Base Sequence; Binding Sites; Computer Simulation; DNA; DNA-Binding Proteins; Escherichia coli; Fungal Proteins; Gene Expression; Histidine; Leucine Zippers; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Kinases; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Trans-Activators; Tyrosine | 1994 |
Residues specific for class III alcohol dehydrogenase. Site-directed mutagenesis of the human enzyme.
Topics: Alcohol Dehydrogenase; Asparagine; Base Sequence; Binding Sites; Fomepizole; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Pyrazoles; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1994 |
Lowering the intrinsic pKa of the chromophore's Schiff base can restore its light-induced deprotonation in the inactive Tyr-57-->Asn mutant of bacteriorhodopsin.
Topics: Amino Acid Sequence; Asparagine; Bacteriorhodopsins; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Point Mutation; Retinaldehyde; Schiff Bases; Spectrophotometry; Tyrosine | 1994 |
Amino/aromatic interactions in proteins: is the evidence stacked against hydrogen bonding?
Topics: Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Benzene; Calorimetry; Guanidine; Guanidines; Histidine; Hydrogen Bonding; Mathematics; Models, Molecular; Phenylalanine; Protein Conformation; Proteins; Tryptophan; Tyrosine | 1994 |
Glycosylation of two recombinant human uterine tissue plasminogen activator variants carrying an additional N-glycosylation site in the epidermal-growth-factor-like domain.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Female; Genetic Variation; Glycine; Glycopeptides; Glycosylation; Humans; Mass Spectrometry; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligosaccharides; Peptide Mapping; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Tissue Plasminogen Activator; Tyrosine; Uterus | 1994 |
Crystal structures of mutant Pseudomonas aeruginosa p-hydroxybenzoate hydroxylases: the Tyr201Phe, Tyr385Phe, and Asn300Asp variants.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Asparagine; Aspartic Acid; Crystallization; Crystallography, X-Ray; Electrochemistry; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Structure; Mutation; Parabens; Phenylalanine; Pseudomonas aeruginosa; Tyrosine | 1994 |
A hydrogen-bonding network modulating enzyme function: asparagine-194 and tyrosine-225 of Escherichia coli aspartate aminotransferase.
Topics: Asparagine; Aspartate Aminotransferases; Base Sequence; Binding Sites; Catalysis; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Maleates; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Spectrophotometry; Structure-Activity Relationship; Tyrosine | 1993 |
Site-directed alteration of three active-site residues of a pyruvoyl-dependent histidine decarboxylase.
Topics: Alanine; Allosteric Regulation; Asparagine; Binding Sites; Histidine; Histidine Decarboxylase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Phenylalanine; Pyruvates; Pyruvic Acid; Recombinant Proteins; Tyrosine; Valine | 1993 |
Autosomal dominant cone-rod dystrophy associated with mutations in codon 244 (Asn244His) and codon 184 (Tyr184Ser) of the peripherin/RDS gene.
Topics: Adult; Aged; Amino Acid Sequence; Asparagine; Base Sequence; Codon; DNA; Electroretinography; Eye Proteins; Female; Fluorescein Angiography; Histidine; Humans; Intermediate Filament Proteins; Male; Membrane Glycoproteins; Middle Aged; Molecular Sequence Data; Nerve Tissue Proteins; Pedigree; Peripherins; Photoreceptor Cells; Point Mutation; Polymorphism, Single-Stranded Conformational; Retinal Degeneration; Serine; Tyrosine; Visual Fields | 1996 |
Mutation of Tyr235 in the NAD(H)-binding subunit of the proton-translocating nicotinamide nucleotide transhydrogenase of Rhodospirillum rubrum affects the conformational dynamics of a mobile loop and lowers the catalytic activity of the enzyme.
Topics: Asparagine; Binding Sites; Biological Transport; Catalysis; Magnetic Resonance Spectroscopy; NAD; NADP Transhydrogenases; Phenylalanine; Protein Conformation; Rhodospirillum rubrum; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan; Tyrosine | 1996 |
Contributions of asparagine at alpha 97 to the cooperative oxygenation process of hemoglobin.
Topics: Adult; Allosteric Regulation; Amino Acid Sequence; Asparagine; Base Sequence; Crystallography, X-Ray; DNA Primers; Hemoglobin A; Hemoglobins, Abnormal; Humans; Hydrogen Bonding; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxyhemoglobins; Phytic Acid; Point Mutation; Protein Conformation; Recombinant Proteins; Thermodynamics; Tyrosine | 1996 |
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Cloning, Molecular; Collagenases; Enzyme Activation; Enzyme Precursors; Gelatinases; Humans; Kinetics; Leucine; Matrix Metalloproteinase 1; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; Substrate Specificity; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tyrosine | 1996 |
Unaccustomed high-mileage vs intensity training-related changes in performance and serum amino acid levels.
Topics: Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cystine; Erythrocyte Count; Exercise Test; Fatigue; Glycine; Hematocrit; Hemoglobins; Humans; Lactates; Leukocyte Count; Lysine; Methionine; Phenylalanine; Physical Endurance; Prospective Studies; Running; Serine; Taurine; Tryptophan; Tyrosine | 1996 |
Involvement of a residue at position 75 in the catalytic mechanism of a fungal aspartic proteinase, Rhizomucor pusillus pepsin. Replacement of tyrosine 75 on the flap by asparagine enhances catalytic efficiency.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Glycosylation; Hydrogen Bonding; Kinetics; Mucorales; Mutagenesis, Site-Directed; Pepsin A; Pepstatins; Protease Inhibitors; Recombinant Proteins; Spectrophotometry, Ultraviolet; Tyrosine | 1996 |
Mechanism of Ca2+ and monosaccharide binding to a C-type carbohydrate-recognition domain of the macrophage mannose receptor.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Binding Sites; Calcium; Kinetics; Lectins; Lectins, C-Type; Macrophages; Magnetic Resonance Spectroscopy; Mannose Receptor; Mannose-Binding Lectins; Mice; Models, Molecular; Monosaccharides; Mutagenesis, Site-Directed; Phenotype; Rats; Receptors, Cell Surface; Tyrosine | 1997 |
Mutant RecA proteins which form hexamer-sized oligomers.
Topics: Arginine; Asparagine; Bacteria; Chromatography, Liquid; Crystallography, X-Ray; DNA Repair; Lysine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Rec A Recombinases; Tyrosine | 1997 |
Demonstration of coiled-coil interactions within the kinesin neck region using synthetic peptides. Implications for motor activity.
Topics: Amino Acid Sequence; Asparagine; Chromatography, Gel; Circular Dichroism; Glutamine; Humans; Kinesins; Lasers; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Scattering, Radiation; Structure-Activity Relationship; Tyrosine | 1997 |
DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kinetics.
Topics: Animals; Asparagine; Binding Sites; Brain; DNA; DNA Polymerase I; DNA Replication; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis; Protein Conformation; Rats; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1997 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
Evidence for a direct interaction between insulin receptor substrate-1 and Shc.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Asparagine; Binding Sites; Humans; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Binding; Proteins; Recombinant Fusion Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tyrosine | 1997 |
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding.
Topics: Asparagine; Binding Sites; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tyrosine | 1997 |
Hypertrophic obstructive cardiomyopathy due to a novel T-to-A transition at codon 624 in the beta-myosin heavy chain (beta-MHC) gene possibly related to the sudden death.
Topics: Amyl Nitrite; Asparagine; Aspirin; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Codon; Death, Sudden, Cardiac; Echocardiography, Doppler; Electrocardiography; Female; Heart Septum; Humans; Middle Aged; Mitral Valve; Myosin Heavy Chains; Point Mutation; Tyrosine | 1997 |
Biochemical characterization of the 20S proteasome from the methanoarchaeon Methanosarcina thermophila.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine Endopeptidases; DNA, Archaeal; Escherichia coli; Glutamine; Ions; Lysine; Methanosarcina; Microscopy, Electron; Molecular Sequence Data; Multienzyme Complexes; Peptides; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Threonine; Tyrosine | 1998 |
Binding of human urokinase-type plasminogen activator to its receptor: residues involved in species specificity and binding.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding, Competitive; Cells, Cultured; Cricetinae; Endothelium, Vascular; Humans; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Sequence Homology, Amino Acid; Species Specificity; Swine; Tyrosine; Urokinase-Type Plasminogen Activator | 1998 |
Preserved catalytic activity in an engineered ribonucleotide reductase R2 protein with a nonphysiological radical transfer pathway. The importance of hydrogen bond connections between the participating residues.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Catalysis; Escherichia coli; Free Radicals; Glutamic Acid; Hydrogen Bonding; Iron; Protein Binding; Protein Engineering; Ribonucleotide Reductases; Tyrosine | 1998 |
Hb Nancy and Hb Osler: two distinct genetic variants with identical clinical and hemoglobin phenotype.
Topics: Asparagine; Aspartic Acid; Base Sequence; Black People; Codon; France; Globins; Hemoglobins, Abnormal; Humans; Phenotype; Polymerase Chain Reaction; Tyrosine; United States; White People | 1998 |
Oxygenic photosystem II: the mutation D1-D61N in Synechocystis sp. PCC 6803 retards S-state transitions without affecting electron transfer from YZ to P680+.
Topics: Asparagine; Aspartic Acid; Chlorophyll; Cyanobacteria; Electron Transport; Light; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Photosynthetic Reaction Center Complex Proteins; Polarography; Spectrophotometry; Tyrosine | 1998 |
Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; COS Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Tertiary; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Fusion Proteins; Recombinant Proteins; Transfection; Tyrosine | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Are His63Asp or Cys282Tyr HFE mutations associated with porphyria cutanea tarda? Data of patients from central and southern Italy.
Topics: Asparagine; Cysteine; Histidine; Humans; Italy; Point Mutation; Porphyria Cutanea Tarda; Tyrosine | 1998 |
Contribution to Tl+, K+, and Na+ binding of Asn776, Ser775, Thr774, Thr772, and Tyr771 in cytoplasmic part of fifth transmembrane segment in alpha-subunit of renal Na,K-ATPase.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cytoplasm; Hydroxides; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Potassium; Protein Structure, Tertiary; Recombinant Proteins; Serine; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thallium; Threonine; Tyrosine | 1998 |
Asn249Tyr substitution at the coenzyme binding domain activates Sulfolobus solfataricus alcohol dehydrogenase and increases its thermal stability.
Topics: Alcohol Dehydrogenase; Amides; Asparagine; Binding Sites; Chromatography, High Pressure Liquid; Circular Dichroism; Coenzymes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Stability; Escherichia coli; Guanidine; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Peptide Fragments; Protein Denaturation; Recombinant Proteins; Spectrometry, Fluorescence; Sulfolobus; Tyrosine | 1999 |
Functional role of oxygen-containing residues in the fifth transmembrane segment of the Na,K-ATPase alpha subunit.
Topics: Amino Acid Substitution; Asparagine; HeLa Cells; Humans; Mutagenesis, Site-Directed; Oxygen; Protein Conformation; Sodium-Potassium-Exchanging ATPase; Threonine; Tyrosine | 1999 |
Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Deoxyribonuclease I; DNA; Hydrolysis; Mutagenesis, Site-Directed; RNA, Transfer, Tyr; Serine; Substrate Specificity; Sugar Phosphates; Threonine; Thymidine; Tyrosine | 1999 |
Phage phi29 terminal protein residues Asn80 and Tyr82 are recognition elements of the replication origins.
Topics: Amino Acid Sequence; Asparagine; Molecular Sequence Data; Replication Origin; Tyrosine; Viral Proteins | 1999 |
A new mutation in the myophosphorylase gene (Asn684Tyr) in a Spanish patient with McArdle's disease.
Topics: Adult; Amino Acid Substitution; Asparagine; Base Sequence; DNA; DNA Mutational Analysis; Glycogen Storage Disease Type V; Humans; Male; Mutation, Missense; Phosphorylases; Spain; Tyrosine | 1999 |
Steady-state kinetic characterization of RB69 DNA polymerase mutants that affect dNTP incorporation.
Topics: Alanine; Asparagine; Bacteriophage T4; Deoxyguanine Nucleotides; Dinucleoside Phosphates; DNA-Directed DNA Polymerase; Enzyme Activation; Exodeoxyribonucleases; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Substrate Specificity; Tyrosine; Viral Proteins | 1999 |
Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic.
Topics: Adaptor Proteins, Signal Transducing; Asparagine; Carrier Proteins; Crystallography, X-Ray; Cyclohexanes; Drug Design; ErbB Receptors; Models, Molecular; Molecular Mimicry; src Homology Domains; Tyrosine | 1999 |
Potent inhibitory ligands of the GRB2 SH2 domain from recombinant peptide libraries.
Topics: Adaptor Proteins, Signal Transducing; Animals; Asparagine; Bacteriophages; Cloning, Molecular; COS Cells; Gene Expression; GRB2 Adaptor Protein; Humans; Ligands; Peptide Library; Peptides; Phosphorylation; Proteins; Recombinant Fusion Proteins; Sequence Analysis; src Homology Domains; Tyrosine | 1999 |
Binding affinity of N-glycans for aromatic amino acid residues: implications for novel interactions between N-glycans and proteins.
Topics: Amino Acids; Animals; Asparagine; Binding, Competitive; Cattle; Dose-Response Relationship, Drug; Lactalbumin; Phenylalanine; Polysaccharides; Protein Binding; Ribonuclease, Pancreatic; Spectrometry, Fluorescence; Sucrose; Tryptophan; Tyrosine | 1999 |
The functions of the flavin contact residues, alphaArg249 and betaTyr16, in human electron transfer flavoprotein.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Animals; Arginine; Asparagine; Circular Dichroism; Electron Transport; Electron-Transferring Flavoproteins; Flavoproteins; Glutaryl-CoA Dehydrogenase; Humans; Hydroquinones; Kinetics; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinones; Rats; Spectrometry, Fluorescence; Spectrophotometry; Swine; Tyrosine | 1999 |
Interrupting the hydrogen bond network at the active site of human manganese superoxide dismutase.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Crystallography, X-Ray; Histidine; Humans; Hydrogen Bonding; Isoenzymes; Kinetics; Least-Squares Analysis; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 1999 |
Expression and function of the gonadotropin-releasing hormone receptor are dependent on a conserved apolar amino acid in the third intracellular loop.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Conserved Sequence; COS Cells; Gonadotropin-Releasing Hormone; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Kinetics; Leucine; Mice; Models, Molecular; Mutagenesis, Site-Directed; Proline; Protein Structure, Secondary; Radioligand Assay; Receptors, LHRH; Transfection; Tyrosine | 1999 |
Fibrinogen Bastia (gamma 318 Asp-->Tyr) a novel abnormal fibrinogen characterized by defective fibrin polymerization.
Topics: Adult; Amino Acid Substitution; Asparagine; Dimerization; Female; Fibrin; Fibrinogens, Abnormal; Humans; Point Mutation; Tyrosine | 1999 |
[Demonstration of HFE polymorphism in German patients with hereditary hemochromatosis].
Topics: Amino Acid Sequence; Asparagine; Chromosomes, Human, Pair 6; Codon; Cysteine; Germany; Hemochromatosis; Heterozygote; Histidine; HLA Antigens; Homozygote; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Tyrosine | 1999 |
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Asparagine; Aspartic Acid; Binding Sites; Catalysis; Equilenin; Glutamic Acid; Hydrogen Bonding; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Nandrolone; Pseudomonas putida; Steroid Isomerases; Tyrosine | 2000 |
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
Topics: Amidohydrolases; Aminolevulinic Acid; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diazooxonorleucine; Electrons; Enzyme Inhibitors; Glutamic Acid; Glutamine; Pseudomonas; Threonine; Tyrosine | 2000 |
Functional inactivation of the nociceptin receptor by alanine substitution of glutamine 286 at the C terminus of transmembrane segment VI: evidence from a site-directed mutagenesis study of the ORL1 receptor transmembrane-binding domain.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; CHO Cells; Cricetinae; Glutamine; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Nociceptin Receptor; Phenylalanine; Protein Conformation; Receptors, Opioid; Signal Transduction; Tryptophan; Tyrosine | 2000 |
D-LysAsnProTyr tetrapeptide: a novel B-cell stimulant and stabilized bursin mimetic.
Topics: Animals; Asparagine; B-Lymphocyte Subsets; Cells, Cultured; Female; Half-Life; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Molecular Mimicry; Oligopeptides; Proline; Spleen; Tyrosine | 2000 |
Citrobacter freundii tyrosine phenol-lyase: the role of asparagine 185 in modulating enzyme function through stabilization of a quinonoid intermediate.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartate Aminotransferases; Citrobacter freundii; Hydrogen Bonding; Kinetics; Models, Theoretical; Mutagenesis, Site-Directed; Protein Conformation; Quinones; Recombinant Proteins; Software; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 2000 |
Directed molecular evolution of cytochrome c peroxidase.
Topics: Alanine; Asparagine; Aspartic Acid; Cloning, Molecular; Cytochrome-c Peroxidase; Directed Molecular Evolution; Enzyme Activation; Gene Library; Genetic Vectors; Guaiacol; Point Mutation; Saccharomyces cerevisiae; Substrate Specificity; Threonine; Tyrosine | 2000 |
Dynamics of a mobile loop at the active site of Escherichia coli asparaginase.
Topics: Asparaginase; Asparagine; Binding Sites; Catalysis; Enzyme Stability; Escherichia coli; Fluorescence; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Mutation; Temperature; Time Factors; Tryptophan; Tyrosine | 2000 |
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2000 |
Role of the conserved acidic residue Asp21 in the structure of phosphatidylinositol 3-kinase Src homology 3 domain: circular dichroism and nuclear magnetic resonance studies.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Circular Dichroism; Conserved Sequence; Histidine; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phenylalanine; Phosphatidylinositol 3-Kinases; Protein Conformation; src Homology Domains; Tyrosine | 2001 |
Topology and structure of the C1q-binding site on C-reactive protein.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; C-Reactive Protein; Complement Activation; Complement C1q; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylcholine; Polysaccharides, Bacterial; Serum Albumin, Bovine; Streptococcus pneumoniae; Threonine; Tyrosine | 2001 |
Mechanism of phosphoryl transfer by nucleoside diphosphate kinase pH dependence and role of the active site Lys16 and Tyr56 residues.
Topics: Adenosine Triphosphate; Animals; Asparagine; Catalysis; Crystallography, X-Ray; Dictyostelium; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Phosphorus; Protein Conformation; Structure-Activity Relationship; Tyrosine | 2001 |
The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition.
Topics: Aminobutyrates; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; Electrons; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Models, Molecular; Salmonella typhimurium; Spectroscopy, Fourier Transform Infrared; Static Electricity; Substrate Specificity; Thallium; Tyrosine | 2001 |
Vaccinia topoisomerase mutants illuminate conformational changes during closure of the protein clamp and assembly of a functional active site.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Binding Sites; Catalytic Domain; DNA; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Magnesium Chloride; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Serine; Sodium Chloride; Time Factors; Tyrosine; Vaccinia virus | 2001 |
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Alanine; Amino Acid Substitution; Anaerobiosis; Asparagine; Aspartic Acid; Catalysis; Flavin-Adenine Dinucleotide; Hydroxylation; Lysine; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Parabens; Phenylalanine; Riboflavin; Serine; Spectrophotometry; Substrate Specificity; Tyrosine | 2001 |
Tryptophan residues at subunit interfaces used as fluorescence probes to investigate homotropic and heterotropic regulation of aspartate transcarbamylase.
Topics: Allosteric Regulation; Asparagine; Aspartate Carbamoyltransferase; Aspartic Acid; Escherichia coli; Fluorescent Dyes; Kinetics; Peptide Fragments; Phenylalanine; Phosphonoacetic Acid; Spectrometry, Fluorescence; Substrate Specificity; Titrimetry; Tryptophan; Tyrosine | 2001 |
N219Y, a new frequent mutation among mut(degree) forms of methylmalonic acidemia in Caucasian patients.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Child; Child, Preschool; Female; Humans; Infant; Lipid Metabolism, Inborn Errors; Male; Methylmalonic Acid; Methylmalonyl-CoA Mutase; Molecular Sequence Data; Mutation, Missense; Tyrosine; White People | 2001 |
Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Binding Sites; Cell Separation; COS Cells; Cross-Linking Reagents; Cysteine; Dimerization; DNA, Complementary; Epitopes; Flow Cytometry; Glycine; Humans; Interleukin Receptor Common gamma Subunit; Interleukin-15; Interleukin-2; Interleukin-4; Interleukin-7; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Cytokine; Receptors, Interleukin-7; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2002 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
Topics: Arginine; Asparagine; Aspartic Acid; Crystallography, X-Ray; Humans; Models, Molecular; Muramidase; Mutation; Protein Binding; Protein Conformation; Serine; Thermodynamics; Tyrosine; Valine; Water | 2002 |
Analysis of receptor (CD46, CD150) usage by measles virus.
Topics: Animals; Antigens, CD; Asparagine; CHO Cells; Cricetinae; Giant Cells; Glycoproteins; Hemagglutinins, Viral; Humans; Immunoglobulins; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Receptors, Cell Surface; Receptors, Virus; Recombination, Genetic; Signaling Lymphocytic Activation Molecule Family Member 1; Tyrosine; Virus Replication | 2002 |
Molecular modeling and site-specific mutagenesis of the histamine-binding site of the histamine H4 receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Calcium; Cells, Cultured; Histamine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sequence Homology, Amino Acid; Serine; Tyrosine | 2002 |
An active site homology model of phenylalanine ammonia-lyase from Petroselinum crispum.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Glutamine; Histidine Ammonia-Lyase; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Petroselinum; Phenylalanine Ammonia-Lyase; Sequence Homology; Substrate Specificity; Tyrosine | 2002 |
Effects of mutations at tyrosine 66 and asparagine 123 in the active site pocket of Escherichia coli uracil DNA glycosylase on uracil excision from synthetic DNA oligomers: evidence for the occurrence of long-range interactions between the enzyme and subs
Topics: Asparagine; Binding Sites; DNA Glycosylases; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genotype; Humans; Mutation; N-Glycosyl Hydrolases; Oligonucleotides; Protein Binding; Substrate Specificity; Tyrosine; Uracil; Uracil-DNA Glycosidase; Viral Proteins | 2002 |
Specific characterization of substrate and inhibitor binding sites of a glycosyl hydrolase family 11 xylanase from Aspergillus niger.
Topics: Amino Acid Sequence; Asparagine; Aspergillus niger; Binding Sites; Chromatography, High Pressure Liquid; Circular Dichroism; Cloning, Molecular; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Immunoblotting; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; N-Glycosyl Hydrolases; Pichia; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Surface Plasmon Resonance; Time Factors; Tryptophan; Tyrosine; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
Differential ligand recognition by the Src and phosphatidylinositol 3-kinase Src homology 3 domains: circular dichroism and ultraviolet resonance Raman studies.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Circular Dichroism; Kinetics; Ligands; Peptide Fragments; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins pp60(c-src); Spectrum Analysis, Raman; src Homology Domains; Tryptophan; Tyrosine | 2003 |
Distinct sites regulating grayanotoxin binding and unbinding to D4S6 of Na(v)1.4 sodium channel as revealed by improved estimation of toxin sensitivity.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Membrane; Cloning, Molecular; Diterpenes; DNA, Complementary; Electrophysiology; Kinetics; Models, Chemical; Molecular Sequence Data; Muscle Proteins; Mutagenesis, Site-Directed; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Phenylalanine; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Serine; Sodium Channels; Transfection; Tyrosine | 2003 |
Mechanism of flavin mononucleotide cofactor binding to the Desulfovibrio vulgaris flavodoxin. 1. Kinetic evidence for cooperative effects associated with the binding of inorganic phosphate and the 5'-phosphate moiety of the cofactor.
Topics: Alanine; Apoproteins; Asparagine; Binding Sites; Desulfovibrio vulgaris; Flavin Mononucleotide; Flavodoxin; Histidine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Phosphates; Protein Binding; Riboflavin; Spectrometry, Fluorescence; Thermodynamics; Threonine; Tryptophan; Tyrosine | 2003 |
Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies.
Topics: Animals; Asparagine; Cholecystokinin; COS Cells; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Tyrosine | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
Specific mutations within the alpha4-alpha5 loop of the Bacillus thuringiensis Cry4B toxin reveal a crucial role for Asn-166 and Tyr-170.
Topics: Aedes; Amino Acid Sequence; Animals; Asparagine; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Endotoxins; Hemolysin Proteins; Inclusion Bodies; Insecticides; Larva; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Tyrosine | 2003 |
Conformational changes detected in a sensory rhodopsin II-transducer complex.
Topics: Archaea; Archaeal Proteins; Asparagine; Carotenoids; Deuterium Oxide; Halorhodopsins; Hydrogen-Ion Concentration; Models, Molecular; Natronobacterium; Plasmids; Protein Binding; Protein Conformation; Proteolipids; Recombinant Fusion Proteins; Rhodopsin; Sensory Rhodopsins; Signal Transduction; Spectroscopy, Fourier Transform Infrared; Tyrosine; Water; X-Rays | 2003 |
Importance of low-oligomeric-weight species for prion propagation in the yeast prion system Sup35/Hsp104.
Topics: Asparagine; Cytosol; Fungal Proteins; Glutamine; Heat-Shock Proteins; Magnetic Resonance Spectroscopy; Models, Biological; Peptide Biosynthesis; Peptide Termination Factors; Peptides; Prions; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors; Tyrosine | 2003 |
Re-evaluation of intramolecular long-range electron transfer between tyrosine and tryptophan in lysozymes. Evidence for the participation of other residues.
Topics: Animals; Asparagine; Binding Sites; Dimerization; Free Radicals; Glycine; Humans; Kinetics; Muramidase; Peptide Fragments; Pulse Radiolysis; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Tryptophan; Tyrosine | 2003 |
[Thin layer chromatographic separation of amino acids on cellulose layers].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Methionine; Serine; Tryptophan; Tyrosine; Valine | 1962 |
[RESEARCH ON THE NUTRITION OF ERWINIA CAROTOVORA].
Topics: Alanine; Aminobutyrates; Ammonium Compounds; Arginine; Asparagine; Aspartic Acid; Boron; Calcium; Cobalt; Copper; Creatine; Creatinine; Culture; Culture Media; Cysteine; Cystine; Erwinia; Glutamates; Glycine; Iron; Lysine; Magnesium; Manganese; Methionine; Minerals; Molybdenum; Pectobacterium carotovorum; Proteins; Quaternary Ammonium Compounds; Tryptophan; Tyrosine; Zinc | 1963 |
INDUCED, SOLUBLE PHENYLALANINE HYDROXYLASE FROM PSEUDOMONAS SP. GROWN ON PHENYLALANINE OR TYROSINE.
Topics: Asparagine; Mixed Function Oxygenases; NAD; Phenylalanine; Phenylalanine Hydroxylase; Physiological Phenomena; Proteins; Pseudomonas; Research; Tyrosine | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
[ON THE QUANTITATIVE DETERMINATION OF AMINO ACIDS USING HIGH VOLTAGE ELECTROPHORESIS].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Blood Protein Electrophoresis; Glutamates; Histidine; Leucine; Lysine; Methionine; Ornithine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
[APPLICATION OF THIN-LAYER CHROMATOGRAPHY TO SEQUENCE ANALYSIS OF PEPTIDES. 3. NONDESTRUCTIVE DETECTION OF AMINO ACIDS ON THE THIN-LAYER CHROMATOGRAM].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chromatography; Chromatography, Thin Layer; Histidine; Peptides; Proline; Research; Sequence Analysis; Serine; Tyrosine; Valine | 1964 |
PHENYLALANINE HYDROXYLATION BY PSEUDOMONAS SPECIES (ATCC 11299A).
Topics: Asparagine; Carbon Isotopes; Culture Media; Hydroxylation; Iron; Keto Acids; Metabolism; Mixed Function Oxygenases; NAD; Phenylalanine; Pseudomonas; Pterins; Radiometry; Research; Tyrosine | 1965 |
AMINO ACID UTILIZATION BY ALCALIGENES VISCOLACTIS FOR GROWTH AND SLIME PRODUCTION.
Topics: Alcaligenes; Amino Acids; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Colorimetry; Culture Media; Glucose; Glutamic Acid; Glutamine; Lactose; Nitrogen; Proline; Research; Salts; Tyrosine | 1965 |
RNA CODEWORDS AND PROTEIN SYNTHESIS, VI. ON THE NUCLEOTIDE SEQUENCES OF DEGENERATE CODEWORD SETS FOR ISOLEUCINE, TYROSINE, ASPARAGINE, AND LYSINE.
Topics: Asparagine; Base Sequence; Carbon Isotopes; Escherichia coli; Genetic Code; Isoleucine; Lysine; Nucleotides; Protein Biosynthesis; Proteins; Research; Ribosomes; RNA; Tyrosine | 1965 |
NEMATODE BIOCHEMISTRY. V. INTERMEDIARY METABOLISM AND AMINO ACID INTERCONVERSIONS IN CAENORHABDITIS BRIGGSAE.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Bicarbonates; Caenorhabditis; Carbon Dioxide; Chromatography; Formates; Glutamates; Glutamine; Glycine; Malates; Nematoda; Phenylalanine; Research; Serine; Taurine; Tyrosine | 1965 |
Nicastrin gene in familial and sporadic Alzheimer's disease.
Topics: Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoprotein E4; Apolipoproteins E; Asparagine; Case-Control Studies; Female; Genotype; Humans; Male; Membrane Glycoproteins; Mutation, Missense; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2003 |
Site within N-Methyl-D-aspartate receptor pore modulates channel gating.
Topics: Asparagine; Calcium; Cells, Cultured; Glutamic Acid; Humans; Ion Channels; Mutagenesis, Site-Directed; Mutation; Protein Structure, Secondary; Receptors, N-Methyl-D-Aspartate; Transfection; Tyrosine | 2004 |
Purification and characterization of the human erythrocyte band 3 protein C-terminal domain.
Topics: Amino Acid Sequence; Anion Exchange Protein 1, Erythrocyte; Asparagine; Endopeptidases; Erythrocyte Membrane; Glycophorins; HeLa Cells; Humans; Hydrolysis; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Trypsin; Two-Hybrid System Techniques; Tyrosine; Valine | 2004 |
Functional characterization of nitric oxide and YC-1 activation of soluble guanylyl cyclase: structural implication for the YC-1 binding site?
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; COS Cells; Cyclic GMP; Cysteine; Cytosol; DNA Mutational Analysis; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitric Oxide; Phenotype; Protein Subunits; Pyrazoles; Pyridines; Rats; Solubility; Tyrosine | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Animals; Asparagine; Aspartic Acid; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-met; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Tyrosine; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity.
Topics: Alanine; Amino Acid Sequence; Animals; Arginine; Asparagine; Catalysis; Granzymes; Isoleucine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Library; Protein Conformation; Protein Structure, Tertiary; Rats; Serine Endopeptidases; Substrate Specificity; Thermodynamics; Tyrosine | 2004 |
Time-resolved absorption and UV resonance Raman spectra reveal stepwise formation of T quaternary contacts in the allosteric pathway of hemoglobin.
Topics: Absorption; Allosteric Regulation; Asparagine; Carboxyhemoglobin; Dimerization; Hemoglobin A; Humans; Hydrogen Bonding; Kinetics; Models, Chemical; Models, Molecular; Photolysis; Protein Structure, Quaternary; Protein Structure, Tertiary; Reference Standards; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 2004 |
A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity.
Topics: Actins; Animals; Apoptosis; Asparagine; Aspartic Acid; Becaplermin; Binding Sites; Cells, Cultured; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Flow Cytometry; Genetic Vectors; Humans; Kinetics; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Point Mutation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Substrate Specificity; Time Factors; Tyrosine; Up-Regulation; Wound Healing | 2004 |
Identification of CC chemokine receptor 7 residues important for receptor activation.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Membrane; Chemokine CCL19; Chemokine CCL21; Chemokines, CC; Chemotaxis; CHO Cells; COS Cells; Cricetinae; Dose-Response Relationship, Drug; Electroporation; Glutamine; Guanine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inhibitory Concentration 50; Jurkat Cells; Ligands; Lysine; Molecular Sequence Data; Mutation; Peptides; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, CCR7; Receptors, Chemokine; Sequence Homology, Amino Acid; Time Factors; Transfection; Tyrosine | 2004 |
A novel presenilin 1 mutation (Y154N) in a patient with early onset Alzheimer's disease with spastic paraparesis.
Topics: Alzheimer Disease; Asparagine; Female; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Paraparesis, Spastic; Pedigree; Presenilin-1; Tyrosine | 2004 |
Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
Topics: Asparagine; Bacillus cereus; Bacterial Proteins; beta-Amylase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Maltose; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Plant Proteins; Threonine; Tyrosine | 2004 |
Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.
Topics: Asparagine; Binding Sites; Camptothecin; Conserved Sequence; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Enzyme Inhibitors; Histidine; Mutagenesis; Phenylalanine; Saccharomyces cerevisiae; Structure-Activity Relationship; Tyrosine | 2004 |
Identification of the transmembrane metal binding site in Cu+-transporting PIB-type ATPases.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Archaeoglobus fulgidus; Asparagine; Binding Sites; Cation Transport Proteins; Cell Membrane; Conserved Sequence; Copper; Copper-Transporting ATPases; Metals; Methionine; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Serine; Structure-Activity Relationship; Tyrosine | 2004 |
Pivotal molecular determinants of peptidic and collagen triple helicase activities reside in the S3' subsite of matrix metalloproteinase 8 (MMP-8): the role of hydrogen bonding potential of ASN188 and TYR189 and the connecting cis bond.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; CHO Cells; Collagen; Cricetinae; DNA Helicases; Hydrogen Bonding; Matrix Metalloproteinase 8; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Tyrosine | 2005 |
Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Azo Compounds; Binding Sites; Cations, Divalent; Chelating Agents; Cobalt; Copper; Crystallography, X-Ray; Enzyme Inhibitors; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenylalanine; Pyridones; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tyrosine | 2005 |
Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N.
Topics: Alleles; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Isoleucine; Leucine; Neoplasm Proteins; Polymorphism, Single Nucleotide; Transfection; Tyrosine | 2005 |
Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site.
Topics: Asparagine; Bacterial Proteins; Binding Sites; Bromides; Catalytic Domain; Chlorides; Hydrolases; Kinetics; Ligands; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Rhizobium; Spectrometry, Fluorescence; Stereoisomerism; Tryptophan; Tyrosine | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
The DRY motif as a molecular switch of the human oxytocin receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Asparagine; Cell Line; Computational Biology; Computer Simulation; COS Cells; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxytocin; Protein Binding; Receptors, Oxytocin; Signal Transduction; Tyrosine | 2005 |
Functional plasticity in the substrate binding site of beta-secretase.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Asparagine; Aspartic Acid Endopeptidases; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; Endopeptidases; Enzyme Inhibitors; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Conformation; Protein Structure, Secondary; Protons; Serine; Substrate Specificity; Temperature; Tyrosine; Water | 2005 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blotting, Western; Cell Membrane; Cell Proliferation; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Immunoprecipitation; Ligands; Mice; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; NIH 3T3 Cells; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Thymidine; Time Factors; Tyrosine; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Interacting residues in an activated state of a G protein-coupled receptor.
Topics: Alanine; Asparagine; Biological Assay; Cross-Linking Reagents; Disulfides; Dose-Response Relationship, Drug; Genes, Dominant; Genes, Reporter; Histidine; Hydrogen-Ion Concentration; Immunoblotting; Kinetics; Lac Operon; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenotype; Pheromones; Protein Binding; Protein Conformation; Protein Structure, Secondary; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Trypsin; Tyrosine | 2006 |
The amino terminus and the third extracellular loop of CX3CR1 contain determinants critical for distinct receptor functions.
Topics: Amino Acid Sequence; Asparagine; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; Chemotaxis; CX3C Chemokine Receptor 1; Glutamine; Humans; Ligands; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Mutation; Phosphorylation; Protein Structure, Tertiary; Receptors, Chemokine; Signal Transduction; Tyrosine | 2006 |
Probing the adhesive footprints of Mytilus californianus byssus.
Topics: Acetic Acid; Amino Acid Sequence; Animals; Arginine; Asparagine; Bivalvia; Cell Adhesion; Cloning, Molecular; DNA Primers; DNA, Complementary; Electrophoresis; Genetic Variation; Glycine; Isoelectric Point; Models, Chemical; Molecular Sequence Data; Mytilus; Oligonucleotides; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2006 |
Analysing the ability to retain sidechain hydrogen-bonds in mutant proteins.
Topics: Algorithms; Animals; Asparagine; Computational Biology; Humans; Hydrogen Bonding; Models, Molecular; Mutant Proteins; Mutation; Nitrogen; Software; Thermodynamics; Tumor Suppressor Protein p53; Tyrosine | 2006 |
Aspartic acid 214 in Citrobacter freundii tyrosine phenol-lyase ensures sufficient C--H-acidity of the external aldimine intermediate and proper orientation of the cofactor at the active site.
Topics: Alanine; Apoenzymes; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Citrobacter freundii; Coenzymes; Deuterium Oxide; Homoserine; Kinetics; Molecular Structure; Mutation; Phenylalanine; Recombinant Fusion Proteins; Spectrophotometry; Tyrosine; Tyrosine Phenol-Lyase | 2006 |
Diagnostic value of ultrastructural nerve examination in Charcot-Marie-Tooth disease: two CMT 1B cases with pseudo-recessive inheritance.
Topics: Adult; Asparagine; Charcot-Marie-Tooth Disease; Child; Consanguinity; Demyelinating Diseases; DNA Mutational Analysis; Female; Genes, Recessive; Humans; Microscopy, Electron, Transmission; Mutation; Myelin P0 Protein; Myelin Sheath; Peripheral Nerves; Phenylalanine; Serine; Tyrosine | 2007 |
Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Cadherins; Calorimetry; Genetic Engineering; Genetic Variation; Glycine; Humans; Kinetics; Listeria monocytogenes; Models, Molecular; Protein Binding; Protein Conformation; Recombinant Proteins; Serine; Thermodynamics; Tyrosine | 2007 |
A minor beta-structured conformation is the active state of a fusion peptide of vesicular stomatitis virus glycoprotein.
Topics: Amino Acid Sequence; Asparagine; Circular Dichroism; Glutamic Acid; Glycoproteins; Hydrogen-Ion Concentration; Liposomes; Micelles; Models, Chemical; Molecular Conformation; Molecular Sequence Data; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphatidylcholines; Phosphatidylserines; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Tyrosine; Valine; Vesicular stomatitis Indiana virus | 2008 |
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Topics: Amino Acid Motifs; Asparagine; Biochemistry; Carbon-Carbon Lyases; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Fusarium; Glutamic Acid; Kinetics; Magnesium; Models, Chemical; Mutagenesis, Site-Directed; Serine; Tyrosine | 2008 |
Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
Topics: Acetylcholinesterase; Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Glutamine; Isoleucine; Leucine; Mice; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Stereoisomerism; Terbutaline; Tyrosine | 2008 |
Evidence for convergent nucleotide evolution and high allelic turnover rates at the complementary sex determiner gene of Western and Asian honeybees.
Topics: Alleles; Amino Acid Motifs; Amino Acid Sequence; Animals; Asia; Asparagine; Base Sequence; Bees; Europe; Evolution, Molecular; Exons; Female; Genes, Insect; Insect Proteins; Male; Molecular Sequence Data; Phylogeny; Polymorphism, Genetic; Protein Structure, Tertiary; Regression Analysis; Sequence Alignment; Sex Determination Processes; Time Factors; Tyrosine | 2008 |
Structural and functional studies of Bacillus stearothermophilus serine hydroxymethyltransferase: the role of Asn(341), Tyr(60) and Phe(351) in tetrahydrofolate binding.
Topics: Amino Acid Sequence; Asparagine; Geobacillus stearothermophilus; Glycine Hydroxymethyltransferase; Kinetics; Leucovorin; Phenylalanine; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Tyrosine | 2009 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
Contributions of active site residues to cofactor binding and catalysis of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.
Topics: Androsterone; Asparagine; Catalysis; Catalytic Domain; Fluorescence Polarization; Hydroxysteroid Dehydrogenases; Kinetics; Lysine; Mutation; NAD; Protein Binding; Tyrosine | 2010 |
Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization.
Topics: Asparagine; Crystallography, X-Ray; Entropy; GRB2 Adaptor Protein; Hot Temperature; Ligands; Protein Conformation; Protons; src Homology Domains; Tyrosine | 2009 |
The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Line; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA-Binding Proteins; Endonucleases; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; Spodoptera; Transfection; Tyrosine; Ultraviolet Rays; Xeroderma Pigmentosum Group A Protein | 2010 |
Signal relay from sensory rhodopsin I to the cognate transducer HtrI: assessing the critical change in hydrogen-bonding between Tyr-210 and Asn-53.
Topics: Amino Acid Sequence; Archaeal Proteins; Asparagine; Halobacterium salinarum; Halorhodopsins; Hydrogen Bonding; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Sensory Rhodopsins; Signal Transduction; Spectroscopy, Fourier Transform Infrared; Titrimetry; Tyrosine | 2010 |
Bacillus subtilis SSE4 produces subtulene A, a new lipopeptide antibiotic possessing an unusual C15 unsaturated beta-amino acid.
Topics: Adipates; Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Asparagine; Bacillus subtilis; Lipids; Lipopeptides; Magnetic Resonance Spectroscopy; Peptides, Cyclic; Serine; Tyrosine | 2010 |
A novel PRNP Y218N mutation in Gerstmann-Sträussler-Scheinker disease with neurofibrillary degeneration.
Topics: Asparagine; Brain; Disease Progression; DNA Mutational Analysis; Family Health; Female; Frontotemporal Dementia; Gerstmann-Straussler-Scheinker Disease; Humans; Middle Aged; Neurofibrillary Tangles; Prion Proteins; Prions; Tyrosine; Ubiquitin; Voltage-Dependent Anion Channels | 2010 |
Effects of long-term cadmium exposure on growth and metabolomic profile of tomato plants.
Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Asparagine; Cadmium; Cadmium Chloride; Carotenoids; Chlorophyll; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Pollutants; Gene Expression; Plant Leaves; Plant Roots; Proline; Solanum lycopersicum; Terpenes; Time Factors; Tyrosine | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Rampant purifying selection conserves positions with posttranslational modifications in human proteins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Evolution, Molecular; Humans; Models, Genetic; Phylogeny; Protein Processing, Post-Translational; Proteins; Selection, Genetic; Sequence Alignment; Serine; Threonine; Tyrosine | 2011 |
A novel missense mutation in the FGB g. 3354 T>A (p. Y41N), fibrinogen Caracas VIII.
Topics: Adult; Afibrinogenemia; Asparagine; Cell Line; DNA Mutational Analysis; Endothelium, Vascular; Fibrin; Fibrinogens, Abnormal; Humans; Male; Microscopy, Electron; Mutation, Missense; Protein Binding; Thrombin Time; Tyrosine | 2011 |
Molecular analysis of connexin26 asparagine14 mutations associated with syndromic skin phenotypes.
Topics: Adult; Asparagine; Aspartic Acid; Cell Membrane; Child; Connexin 26; Connexins; Cytoplasm; Endoplasmic Reticulum; Female; Fluoresceins; Gap Junctions; Hearing Loss; HeLa Cells; Humans; Hypertrichosis; Keratoderma, Palmoplantar; Keratosis; Lysine; Male; Mutation, Missense; Nails, Malformed; Protein Transport; Skin; Skin Diseases; Syndrome; Transfection; Tyrosine | 2011 |
Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.
Topics: Animals; Animals, Newborn; Asparagine; Behavior, Animal; Cell Count; Cells, Cultured; Cerebral Cortex; Cytoplasmic Dyneins; Dendrites; Embryo, Mammalian; Female; Fibroblasts; Ganglia, Spinal; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neural Conduction; Neurons; Phenotype; Point Mutation; Protein Transport; Psychomotor Performance; Statistics, Nonparametric; Tyrosine; Weight Lifting | 2011 |
The kinase activity of the Helicobacter pylori Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase is sensitive to distal mutations in its putative ammonia tunnel.
Topics: Ammonia; Asparagine; Aspartate-tRNA Ligase; Enzyme Activation; Glutamine; Helicobacter pylori; Lysine; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nitrogenous Group Transferases; Phosphorylation; RNA, Transfer, Amino Acyl; Staphylococcus aureus; Tyrosine | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Selective cleavage of pepsin by molybdenum metallopeptidase.
Topics: Animals; Asparagine; Hot Temperature; Leucine; Metalloproteases; Molybdenum; Pepsin A; Peptide Fragments; Protein Conformation; Sequence Analysis, Protein; Swine; Tyrosine | 2012 |
Precursors and nitrogen origins of trichloronitromethane and dichloroacetonitrile during chlorination/chloramination.
Topics: Acetonitriles; Alanine; Asparagine; Chloramines; Gas Chromatography-Mass Spectrometry; Halogenation; Hydrocarbons, Chlorinated; Hydrogen-Ion Concentration; Nitrogen; Tryptophan; Tyrosine | 2012 |
Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells.
Topics: Acetylcholine; Asparagine; Carbachol; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Point Mutation; Protein Binding; Receptor, Muscarinic M3; Tyrosine | 2012 |
Substitution of asparagine 76 by a tyrosine residue induces domain swapping in Helicobacter pylori phosphopantetheine adenylyltransferase.
Topics: Adenosine Triphosphate; Asparagine; Bacterial Proteins; Coenzyme A; Crystallography, X-Ray; Helicobacter pylori; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Molecular Dynamics Simulation; Mutation; Nucleotidyltransferases; Promoter Regions, Genetic; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Thermodynamics; Tyrosine | 2012 |
Transfer RNA gene numbers may not be completely responsible for the codon usage bias in asparagine, isoleucine, phenylalanine, and tyrosine in the high expression genes in bacteria.
Topics: Asparagine; Bacterial Proteins; Codon; DNA-Directed RNA Polymerases; Gene Dosage; Genes, Bacterial; Genome, Bacterial; Isoleucine; Models, Genetic; Phenylalanine; Protein Biosynthesis; RNA, Bacterial; RNA, Transfer; Tyrosine | 2012 |
[Analysis of surface enhanced Raman scattering spectra of oxyhemoglobin for liver cancer with combined multivariate statistics].
Topics: Algorithms; Asparagine; Discriminant Analysis; Humans; Liver Neoplasms; Oxyhemoglobins; Phenylalanine; Principal Component Analysis; Silver; Spectrum Analysis, Raman; Tyrosine | 2012 |
Crouzon syndrome and Bent bone dysplasia associated with mutations at the same Tyr-381 residue in FGFR2 gene.
Topics: Adult; Asparagine; Bone Diseases, Developmental; Child, Preschool; Craniofacial Dysostosis; Female; Humans; Male; Mutation, Missense; Receptor, Fibroblast Growth Factor, Type 2; Tyrosine | 2014 |
A catalytically essential motif in external loop 5 of the bacterial oligosaccharyltransferase PglB.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Bacterial Proteins; Binding Sites; Biocatalysis; Campylobacter lari; Disulfides; Electrophoresis, Polyacrylamide Gel; Glycosylation; Hexosyltransferases; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2014 |
Molecular insights on TNKS1/TNKS2 and inhibitor-IWR1 interactions.
Topics: Amino Acid Sequence; Asparagine; Catalytic Domain; Crystallography, X-Ray; Databases, Pharmaceutical; Enzyme Inhibitors; Humans; Imides; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary; Quinolines; Tankyrases; Thermodynamics; Tyrosine; Zinc | 2014 |
Increasing prion propensity by hydrophobic insertion.
Topics: Amino Acid Sequence; Amyloid; Asparagine; Blotting, Western; Computational Biology; Glutamine; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Mutagenesis; Mutation; Prions; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Tyrosine | 2014 |
Novel mutation in the PSEN2 gene (N141Y) associated with early-onset autosomal dominant Alzheimer's disease in a Chinese Han family.
Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Asian People; Asparagine; Codon; Female; Genes, Dominant; Genetic Association Studies; Humans; Male; Middle Aged; Mutation, Missense; Pedigree; Phenotype; Presenilin-2; Tyrosine | 2014 |
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures.
Topics: Amino Acid Sequence; Apoenzymes; Archaeal Proteins; Asparagine; Catalytic Domain; Dimerization; Glycine Hydroxymethyltransferase; Holoenzymes; Hot Temperature; Ligands; Methanocaldococcus; Models, Molecular; Mutant Proteins; Protein Conformation; Protein Interaction Domains and Motifs; Protein Stability; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Tyrosine | 2014 |
[Research on Early Diagnosis of Gastric Cancer by the Surface Enhanced Raman Spectroscopy of Human Hemoglobin].
Topics: Asparagine; Early Detection of Cancer; Heme; Hemoglobins; Humans; Methemoglobin; Multivariate Analysis; Oxyhemoglobins; Phenylalanine; Principal Component Analysis; Spectrum Analysis, Raman; Stomach Neoplasms; Tyrosine | 2015 |
Discovery of a potent and highly selective transforming growth factor β receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD).
Topics: Animals; Asparagine; Crystallography, X-Ray; Drug Design; Enzyme Assays; Humans; Hydrogen Bonding; MAP Kinase Kinase Kinases; Mice; Microsomes, Liver; Molecular Structure; Protein Kinase Inhibitors; Pyrimidinones; Serine; Solubility; Structure-Activity Relationship; Thiophenes; Tyrosine | 2016 |
Structure of a serine-type glutathione S-transferase of Ceriporiopsis subvermispora and identification of the enzymatically important non-canonical residues by functional mutagenesis.
Topics: Amino Acids; Asparagine; Coriolaceae; Crystallography, X-Ray; Fungal Proteins; Glutathione; Glutathione Transferase; Ligands; Mutagenesis; Serine; Tyrosine | 2019 |
Queuine links translational control in eukaryotes to a micronutrient from bacteria.
Topics: Animals; Anticodon; Asparagine; DNA (Cytosine-5-)-Methyltransferases; DNA, Mitochondrial; Eukaryota; Guanine; Methylation; Mice; Micronutrients; Protein Biosynthesis; Ribosomes; RNA, Transfer; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine | 2019 |
Asparagine enhances LCK signalling to potentiate CD8
Topics: Animals; Asparagine; CD8-Positive T-Lymphocytes; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Phosphorylation; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured; Tyrosine | 2021 |
Mechanism of action of non-camptothecin inhibitor Genz-644282 in topoisomerase I inhibition.
Topics: Aphidicolin; Arginine; Asparagine; Camptothecin; DNA; DNA Topoisomerases, Type I; Naphthyridines; Tyrosine | 2022 |
Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins.
Topics: Amino Acid Sequence; Asparagine; Dictyostelium; Histidine; Isoleucine; Leucine; Leucine-Rich Repeat Proteins; Phenylalanine; Tryptophan; Tyrosine | 2022 |
An improved method for determining free amino acids by RP-HPLC/DAD with o-phthalaldehyde derivatization: Method evaluation in beers and wines.
Topics: Amino Acids; Arginine; Asparagine; Beer; Chromatography, High Pressure Liquid; o-Phthalaldehyde; Tyrosine; Wine | 2024 |