tyrosine has been researched along with 4-hydroxy-2-nonenal in 162 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (4.32) | 18.2507 |
| 2000's | 81 (50.00) | 29.6817 |
| 2010's | 68 (41.98) | 24.3611 |
| 2020's | 6 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Naito, Y; Nakamura, Y; Osawa, T; Shiraishi, M; Torii, Y; Uchida, K | 1 |
| Hiai, H; Nishimura, Y; Suzuki, S; Toyokuni, S; Uchida, K; Um, SC | 1 |
| Bruns, CM; Hubatsch, I; Mannervik, B; Ridderström, M; Tainer, JA | 1 |
| Akhand, AA; Kato, M; Kurokawa, K; Liu, W; Miyata, T; Nakashima, I; Uchida, K; Yokoyama, I | 1 |
| DiMarco, A; Nethery, D; Stofan, D; Supinski, G; Szweda, L | 1 |
| Perry, G; Sayre, LM; Smith, MA | 1 |
| Hirabayashi, Y; Irie, F | 1 |
| Bellomo, G; Caligiuri, A; De Franco, RM; Dianzani, MU; Gentilini, P; Marra, F; Parola, M; Pinzani, M; Robino, G; Zamara, E | 1 |
| Halliwell, B; Hyun, D; Jenner, P; Lee, M | 1 |
| Araki, S; Hayashi, M; Itoh, M; Kumada, S; Minagawa, M; Mizutani, T; Morimatsu, Y; Oda, M; Shioda, K; Tamagawa, K | 1 |
| Duff, K; La Francois, J; Matsuoka, Y; Picciano, M | 1 |
| Halliwell, B; Hyun, DH; Jenner, P; Lee, M | 2 |
| Ali, SF; Imam, SZ; Mayeux, PR; Muldrew, KL; Walker, LM; York, JL | 1 |
| Burton, GJ; Hung, TH; Skepper, JN | 1 |
| Arnal, JF; Darblade, B; Escargueil-Blanc, I; Jürgens, G; Nègre-Salvayre, A; Parthasarathy, S; Salvayre, R; Vacaresse, N | 1 |
| Becker, BF; Kastenbauer, S; Koedel, U; Pfister, HW | 1 |
| Dzierzega-Lecznar, A; Stepień, K; Wilczok, A; Wilczok, T; Zajdel, A | 1 |
| Ferrington, DA; Kapphahn, RJ; Louie, JL | 1 |
| Hai, S; Minamiyama, Y; Nishino, Y; Okada, S; Takemura, S; Toyokuni, S; Yamamoto, S; Yamasaki, K | 1 |
| Arteel, GE; Connor, HD; Doll, MA; Gäbele, E; Hein, DW; Isayama, F; Lambert, JC; Mason, RP; McKim, SE; Tucker, LM; Wheeler, MD | 1 |
| Detloff, MR; Hall, ED; Johnson, K; Kupina, NC | 1 |
| Boylston, WH; Choksi, KB; Papaconstantinou, J; Rabek, JP; Widger, WR | 1 |
| Barrera, D; Castro, L; Chirino, YI; Hernández-Pando, R; Macías-Ruvalcaba, NA; Maldonado, PD; Medina-Campos, ON; Pedraza-Chaverrí, J; Salcedo, MI | 1 |
| Banks, WA; Butterfield, DA; Calabrese, V; Farr, SA; Joshi, G; Morley, JE; Poon, HF; Sultana, R | 1 |
| Endo, T; Iguchi, F; Ito, J; Kim, TS; Kita, T; Lee, JE; Lee, SH; Nakagawa, T; Shiga, A | 1 |
| Jiang, H; Schacht, J; Sha, SH | 1 |
| Endo, T; Iguchi, F; Ito, J; Kim, TS; Lee, JE; Lee, SH; Nakagawa, T; Shiga, A | 1 |
| Bredenoord, AJ; de Jonge, F; de Man, JG; de Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC; Timmermans, JP; van Nassauw, L | 1 |
| Andersen, JK; Atienza, JG; Di Monte, DA; Johnston, LC; McCormack, AL; Vu, S | 1 |
| Fujimoto, J; Harada, N; Hatano, E; Iimuro, Y; Nishio, T; Son, G; Suetsugu, H; Uehara, T; Yamaoka, Y; Yoshida, M | 1 |
| Beltowski, J; Borkowska, E; Jamroz-Wiśniewska, A; Marciniak, A; Wójcicka, G | 1 |
| Jiang, HY; Le Prell, CG; Miller, JM; Schacht, J; Yamashita, D | 1 |
| Banan, A; Emanuele, MA; Emanuele, NV; Keshavarzian, A; Lapaglia, N; McNulty, J; Ren, JC; Zhu, Q | 1 |
| Arteel, GE; Cai, L; Du, Y; Kang, YJ; Li, Y; Saari, JT; Song, Y; Wang, J | 1 |
| Chaiswing, L; Cole, MP; Ittarat, W; Oberley, TD; St Clair, DK; Szweda, LI | 1 |
| Akaike, A; Hayashi, K; Inden, M; Kitamura, Y; Kondo, J; Nishimura, K; Shimohama, S; Sugimoto, H; Takata, K; Taniguchi, T; Tsuchiya, D; Yanagida, T; Yanagisawa, D | 1 |
| Komine-Kobayashi, M; Liu, M; Mizuno, Y; Tanaka, R; Urabe, T; Zhang, N | 1 |
| Carretero, OA; Lin, C; Pagano, PJ; Rhaleb, NE; Sun, Y; Wang, F; Xu, J; Yang, JJ; Yang, XP | 1 |
| Butterfield, DA; Cole, MP; Estus, S; Joshi, G; St Clair, DK; Sultana, R; Tangpong, J; Vore, M | 1 |
| Beckers-Trapp, ME; Keen, CL; Lanoue, L; Rucker, RB; Uriu-Adams, JY | 1 |
| Bai, J; Cederbaum, AI | 1 |
| Butterfield, DA; Calabrese, V; Coccia, R; De Marco, C; Joshi, G; Perluigi, M; Sultana, R | 1 |
| Grindle, K; Kay, HH; Magness, RR; Tsoi, S | 1 |
| Ilumets, H; Kinnula, VL; Myllärniemi, M; Rehn, T; Rouhos, A; Rytilä, P; Sovijärvi, A | 1 |
| Fox, DA; Haruna, Y; Kashihara, N; Komai, N; Morita, Y; Sakuta, T; Tomita, N; Yada, T | 1 |
| Akishita, M; Eto, M; Hasegawa, H; Kozaki, K; Nagai, K; Toba, K; Xi, H; Yu, W | 1 |
| Jiang, H; Schacht, J; Sha, SH; Talaska, AE | 1 |
| Karihtala, P; Kinnula, VL; Soini, Y; Syväoja, JE; Winqvist, R | 1 |
| Hashimoto, K; Ichihara, G; Ichihara, S; Iwase, M; Kanazawa, H; Kato, Y; Matsushita, A; Oikawa, S; Yamada, Y; Yokota, M | 1 |
| Butterfield, DA; Cotman, CW; Head, E; Joshi, G; Klein, JB; Milgram, NW; Muggenburg, BA; Opii, WO; Pierce, WM | 1 |
| Ansari, GA; Cai, P; Khan, MF; Wang, G | 1 |
| Hall, ED; Rabchevsky, AG; Xiong, Y | 1 |
| Kusakabe, T; Nagamine, T; Nakazato, K; Sakurai, H; Suzuki, K; Takatama, M | 1 |
| Bainbridge, SA; Belkacemi, L; Dickinson, MA; Graham, CH; Smith, GN | 1 |
| Deng, Y; Gao, X; Hall, ED; Thompson, BM | 1 |
| Barron, S; Butterfield, DA; Littleton, JM; Mello, CF; Rubin, MA; Sultana, R | 1 |
| Hall, ED; Singh, IN; Sullivan, PG | 1 |
| Krishnamurthy, S; Pandya, JD; Patel, SP; Rabchevsky, AG; Sullivan, PG | 1 |
| Besson, VC; Chen, XR; Garcia, Y; Marchand-Leroux, C; Palmier, B; Plotkine, M | 1 |
| Isoda, K; Nakazato, Y; Oishi, T; Toyokuni, S; Yokoo, H | 1 |
| Asano, S; Blough, ER; Desai, DH; Kakarla, S; Katta, A; Rice, KM; Walker, EM; Wehner, P | 1 |
| Hatachi, S; Jikimoto, T; Kasagi, S; Kawano, S; Komori, T; Kumagai, S; Kurimoto, C; Nakamura, H; Sugiyama, D; Tsuji, G; Yodoi, J | 1 |
| Dobrota, D; Kaplan, P; Lehotsky, J; Pavlikova, M; Racay, P; Tatarkova, Z | 1 |
| Hall, ED; Mbye, LH; Singh, IN; Springer, JE; Sullivan, PG | 1 |
| Björk-Eriksson, T; Blomgren, K; Eriksson, PS; Fukuda, A; Fukuda, H; Hagberg, H; Korhonen, L; Lannering, B; Lindholm, D; Nilsson, M; Northington, FJ; Wang, X; Xu, F; Zhu, C | 1 |
| Bobadilla, NA; Chirino, YI; Cruz, C; Martínez-Martínez, CM; Pedraza-Chaverri, J; Sánchez-González, DJ; Trujillo, J | 1 |
| Abdul, HM; Batinic-Haberle, I; Butterfield, DA; Chen, Y; Doubinskaia, I; Ittarat, W; Sompol, P; St Clair, DK; Tangpong, J | 1 |
| Arteel, GE | 1 |
| Kregel, KC; Oberley, TD; Swanlund, JM; Zhang, HJ | 1 |
| Akagi, N; Anniko, M; Hirakawa, K; Ishibashi, T; Takumida, M | 1 |
| Avila-Casado, C; Franco, M; Johnson, RJ; Nakagawa, T; Rodríguez-Iturbe, B; Sánchez-Lozada, LG; Sautin, YY; Soto, V; Tapia, E | 1 |
| Pandya, JD; Patel, SP; Rabchevsky, AG; Sullivan, PG | 1 |
| Avila-Casado, C; Franco, M; Johnson, RJ; Martínez-Martínez, CM; Medina-Campos, ON; Pedraza-Chaverrí, J; Rodríguez-Iturbe, B; Sánchez-González, DJ; Sánchez-Lozada, LG; Soto, V; Tapia, E | 1 |
| Chen, CN; Ferrington, DA; Thompson, LV | 1 |
| Butterfield, DA; Opii, WO; Owen, JB; Pierce, WM; Ramassamy, C | 1 |
| Ansari, MA; Keller, JN; Scheff, SW | 1 |
| Bache, RJ; Barsoum, M; Chen, Y; Hou, M; Li, Y; Xu, X; Zhang, P | 1 |
| Augustyniak, A; Skrzydlewska, E | 1 |
| Cooley, BC; Ionova, IA; Khanna, AK; Migrino, RQ; Pieper, GM; Vásquez-Vivar, J; Whitsett, J | 1 |
| Ahokas, RA; Baburyan, NY; Bhattacharya, SK; Deshmukh, PA; Gandhi, MS; Gerling, IC; Johnson, PL; Kamalov, G; Sun, Y; Weber, KT | 1 |
| Butterfield, DA; Reed, T; Sultana, R | 2 |
| Amano, K; Kato, K; Nishiyama, K; Tachikawa, M; Urano, A; Yamanaka, K | 1 |
| Carrico, KM; Hall, ED; Vaishnav, R | 1 |
| Hasegawa, M; Hiroi, M; Ogihara, T; Tamai, H | 1 |
| Chien, CT; Li, PC; Lin, CY; Liou, SY; Yang, CH; Yang, JH | 1 |
| Cai, L; Guo, W; Ji, S; Li, C; Li, X; Tan, Y; Zhang, C | 1 |
| Badham, HJ; Winn, LM | 1 |
| Anniko, M; Hamamoto, T; Hirakawa, K; Ishibashi, T; Takumida, M | 1 |
| Folbergrová, J; Haugvicová, R; Houstek, J; Jesina, P; Lisý, V | 1 |
| Bormann, F; Czerny, C; Henrich, D; Höhn, C; Lehnert, M; Marzi, I; Relja, B; Seyboth, K | 1 |
| Ansari, MA; Scheff, SW | 1 |
| Albert, DM; Darjatmoko, SR; Dubielzig, RR; Neekhra, A; Sheibani, N; Sorenson, CM; Wang, S | 1 |
| Ahmed, M; Girnun, GD; Goldberg, SN; Levchenko, T; Rahmanuddin, S; Schor-Bardach, R; Signoretti, S; Solazzo, SA; Spitz, DR; Torchilin, V; Yang, W | 1 |
| Unger, EC | 1 |
| Chen, Y; Fassett, J; Hu, X; Huang, Y; Li, J; Lu, Z; Tao, Y; Xu, X; Zhang, P; Zhao, B; Zhu, G | 1 |
| Chen, CH; Liu, WW; Manaenko, A; Ostrowki, RP; Tang, J; Zhan, Y; Zhang, JH | 1 |
| Anuradha, CV; Kannappan, S; Palanisamy, N | 1 |
| Abdul Muneer, PM; Alikunju, S; Donohue, TM; Haorah, J; Haorei, C; Jones, J; Keblesh, J; Lamb, A; Liu, J; Persidsky, Y; Rump, TJ; Szlachetka, AM; Xiong, H; Zimmerman, MC | 1 |
| Chew, P; Cooper, ME; Coughlan, MT; de Haan, JB; Jandeleit-Dahm, KA; Pete, J; Rosenfeldt, F; Stefanovic, N; Thomas, MC; Yuen, DY | 1 |
| Furukawa, S; Kimura, H; Kon, N; Matsumoto, K; Mukaida, M; Murakami-Murofushi, K; Sone, H; Yamakura, F | 1 |
| Bergheim, I; Bischoff, SC; Kanuri, G; Spruss, A; Uebel, K | 1 |
| Li, L; Zuo, Z | 1 |
| Barone, E; Butterfield, DA; Cenini, G; Coccia, R; Di Domenico, F; Mancuso, C; Perluigi, M; Preziosi, P; Sultana, R | 1 |
| Bruno, RS; Chung, MY; Koo, SI; Manautou, JE; Park, HJ | 1 |
| Breig, L; Henrich, D; Lehnert, M; Marzi, I; Relja, B; Schneider, H; Töttel, E | 1 |
| Benko, R; Kiss, L; Kovács, E; Lacza, Z; Módis, K; Szabó, C; Szerafin, T | 1 |
| Haider, N; Hoff, M; Kador, P; Kawada, H; Randazzo, J; Sachs, A; Yuan, Y; Zhang, Z | 1 |
| Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH | 1 |
| Davis, TP; Demarco, KM; Finch, JD; Lochhead, JJ; McCaffrey, G; Quigley, CE; Ronaldson, PT; Sanchez-Covarrubias, L | 1 |
| Bonini, MG; Cleland, E; Kadiiska, MB; Ruggiero, C; Stadler, K; Wicks, S | 1 |
| Chen, YK; Guan, F; Lee, MJ; Li, G; Lin, Y; Liu, AB; Shih, W; Yang, CS; Yang, Z | 1 |
| Fales-Williams, AJ; Ghosh, A; Haynes, JS; Kanthasamy, AG; Wong, DM | 1 |
| Drel, VR; El-Remessy, AB; Komissarenko, JI; Lupachyk, S; Obrosov, AA; Obrosova, IG; Pacher, P; Stavniichuk, R | 1 |
| Henrich, D; Lehnert, M; Marzi, I; Relja, B; Wang, M; Wilhelm, K | 1 |
| Cai, J; Lin, B; Qu, J; Snider, BJ; Sun, L; Wu, M; Wu, S | 1 |
| Becker, CM; Bussmann, J; Seebahn, A; Sticht, H; Weisbach, V; Xiang, W; Zimmermann, R | 1 |
| Britto, LR; Leonelli, M; Martins, DO | 1 |
| Bao, F; Liu, D; Shan, Y; Valluru, L | 1 |
| Ari, N; Aydin, E; Cumaoğlu, A; Dilsiz, N; Karasu, C; Sakul, A | 1 |
| Choi, J; Jang, SI; Kim, SZ; Park, KH; Shin, JH | 1 |
| Lupachyk, S; Obrosov, A; Obrosova, IG; Shevalye, H; Vareniuk, I; Watcho, P; Yorek, MA | 1 |
| Lam, L; Nakano, D; Nishiyama, A; Ortiz, RM; Peti-Peterdi, J; Popovich, I; Rodriguez, R; Sonanez-Organis, JG; Thorwald, MA; Vázquez-Medina, JP; Viscarra, JA | 1 |
| Hagiri, S; Hataishi, R; Hirose, M; Kobayashi, H; Kokubo, K; Sato, Y; Shinbo, T | 1 |
| Bozza, F; Castro Faria-Neto, HC; d'Avila, JCP; Ehrenshaft, M; Garteiser, P; Gomez-Mejiba, SE; Lupu, F; Magno, F; Mason, RP; Oliveira, MF; Ramirez, DC; Saunders, D; Silasi-Mansat, R; Smith, N; Towner, RA | 1 |
| Crnčević-Orlić, Z; Cvijanović, O; Domitrović, R; Mikelić, L; Pernjak-Pugel, E; Skoda, M | 1 |
| Akao, H; Aoki, H; Fujibayashi, K; Ishida, R; Kajinami, K; Kawai, Y; Kimura, H; Kitayama, M; Motoyama, A; Saito, R; Tanabe, K; Tsuchiya, T; Wakasa, M; Watanabe, M; Yoshida, K | 1 |
| Farfán-García, ED; Guerra-Araiza, C; Pinto-Almazán, R; Rivas-Arancibia, S; Rodríguez-Martínez, E | 1 |
| Andreazza, AC; Gildengers, A; Mulsant, BH; Rajji, TK; Young, LT; Zuzarte, PM | 1 |
| Cai, J; Cai, L; Cai, X; Tan, Y; Wang, Y; Zheng, Y; Zhou, S | 1 |
| Burrough, ER; Gauger, PC; Schwartz, KJ; Wang, C; Wilberts, BL | 1 |
| Deng, J; Xiong, L; Zuo, Z | 1 |
| Chen, J; Hill, K; Lemasters, J; Sha, SH; Wang, X; Yang, SM; Yuan, H | 1 |
| Harper, MM; Holmes, A; Kardon, RH; Obrosov, A; Shevalye, H; Yorek, MA; Yorek, MS | 1 |
| Baur, JA; Becker, LB; Bhatti, T; Guan, Y; Karamercan, MA; Sims, CA; Wang, H; Ye, L | 1 |
| Amboni, RT; Arent, CO; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Quevedo, J; Resende, WR; Steckert, AV; Valvassori, SS | 1 |
| Choi, YH; Han, MH; Hwang, HJ; Kim, BW; Kim, CM; Kim, GY; Kim, JW; Kim, KY; Kim, SG; Ku, SK | 1 |
| Csont, T; Erdélyi, K; Godó, M; Hamar, P; Kaucsár, T; Kiss, N; Kökény, G; Krenács, T; Lajtár, E; Pacher, P; Révész, C; Sárközy, M; Szalay, CI; Szénási, G | 1 |
| Fuse, A; Kusano, T; Matsuda, Y; Okamoto, K; Suzuki, G; Yamaguchi, M; Yokota, H | 1 |
| Conte, D; Minas, JN; Nishiyama, A; Ortiz, RM; Thorwald, MA; Vázquez-Medina, JP | 1 |
| Cao, F; Cheng, C; Guo, Z; Huang, Z; Jiang, L; Sun, X; Yu, Z; Zhong, J | 1 |
| Huo, Y; Ji, B; Lu, F; Wang, O; Wang, Y; Yang, X; Zhao, L; Zhou, F | 1 |
| Chandra, N; Haorah, J; Heller, A; Mishra, V; Schuetz, H; Skotak, M | 1 |
| Chen, J; Feng, W; Li, X; Lu, X; Tan, Y; Yan, X; Zeng, J; Zhang, C; Zhang, Z; Zhou, S | 1 |
| Cervellati, C; Cervellati, F; Cortelazzo, A; Guerranti, R; Hayek, J; Mirasole, C; Pecorelli, A; Savelli, V; Sticozzi, C; Trentini, A; Valacchi, G; Zolla, L | 1 |
| Bao, Z; Chao, H; Ji, J; Li, Z; Lin, C; Liu, N; Liu, Y; Wang, X; Xu, X; You, Y | 1 |
| Huang, YH; Liu, PH; Tseng, CY; Tseng, GF; Yeh, TY | 1 |
| Adeghate, E; Kader, KH; Kumaraswamy, SM; Mahgoub, E; Ojha, S; Rajesh, M; Venkataraman, B | 1 |
| Cho, HR; Choi, JS; Jung, GW; Ku, SK; Lee, YJ; Lim, JM; Park, DC | 1 |
| Campbell, J; Lakshmanan, R; Maulik, N; McFadden, DW; Selvaraju, V; Thirunavukkarasu, M; Wilson, RL | 1 |
| Bao, D; Chen, Q; Cui, Y; Dai, Y; Fu, H; Hao, Q; Hou, D; Nie, X; Yan, Z; Yin, Y; Zheng, Y | 1 |
| Alcaraz-Zubeldia, M; Cano, GG; Fortoul, TI; Garibay-Huarte, T; González Rendón, ES | 1 |
| Dal-Pont, GC; Menegas, S; Peterle, BR; Quevedo, J; Resende, WR; Trajano, KS; Valvassori, SS; Varela, RB | 1 |
| Austin, GL; Butterfield, DA; Cuello, AC; Do Carmo, S; Foret, MK; Hall, H; Iulita, MF; Jia, DT; Malcolm, JC; Marks, AR; Wilson, EN | 1 |
| Chen, Q; Du, D; Jin, Y; Qin, X; Wang, S; Wen, J; Wu, M; Wu, T; Zhang, J | 1 |
| He, G; Huang, F; Le Grange, JM; Liang, Y; Liu, Y; Tong, F; Zhou, Y; Zhu, L | 1 |
| Botta, A; Dadlani, H; Elango, R; Ghosh, S; Jiayu, Y; Rasmussen, B; Renaud, LM; Simtchouk, S; Winkler, J | 1 |
| Carbonara, P; Civettini, M; Fiocchi, E; Lembo, G; Manfrin, A; Zupa, W | 1 |
| Aktekin, CN; Bek, ZA; Bitik, B; Elmazoglu, Z; Goker, B; Karasu, Ç; Özoğul, C; Sarıbaş, GS | 1 |
| Campo, VE; Cecchini, AL; Cecchini, R; Cela, EM; González-Maglio, DH; Marinello, PC; Melo, GP; Ramalho, LZN; Souza-Neto, FP | 1 |
| Chen, M; Li, Q; Li, S; Lu, T; Min, S; Zhang, C | 1 |
1 review(s) available for tyrosine and 4-hydroxy-2-nonenal
| Article | Year |
|---|---|
Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease.
Topics: Aldehydes; Alzheimer Disease; Brain; Disease Progression; Humans; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Tyrosine | 2011 |
161 other study(ies) available for tyrosine and 4-hydroxy-2-nonenal
| Article | Year |
|---|---|
Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production.
Topics: Aldehydes; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; DNA; Enzyme Activation; Epithelial Cells; Lipid Peroxidation; Lipid Peroxides; Liver; Molecular Sequence Data; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-jun; Quercetin; Rats; Signal Transduction; Tyrosine | 1999 |
Formation of 4-hydroxy-2-nonenal-modified proteins and 3-nitro-L-tyrosine in rat island skin flaps during and after ischemia.
Topics: Aldehydes; Animals; Blotting, Western; Free Radicals; Ischemia; Male; Proteins; Rats; Rats, Wistar; Reperfusion Injury; Skin; Specific Pathogen-Free Organisms; Surgical Flaps; Tyrosine | 1999 |
Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products.
Topics: Aldehydes; Amino Acid Sequence; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; DNA Primers; Glutathione; Glutathione Transferase; Glycine; Humans; Isoenzymes; Lipid Peroxidation; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Conformation; Sequence Homology, Amino Acid; Tyrosine | 1999 |
4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition.
Topics: Aldehydes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cross-Linking Reagents; Enzyme Activation; ErbB Receptors; Genistein; Humans; Lipid Peroxidation; Oxidative Stress; Phosphoproteins; Phosphorylation; Quinazolines; Signal Transduction; Tyrosine; Tyrphostins | 1999 |
Apocynin improves diaphragmatic function after endotoxin administration.
Topics: Acetophenones; Aldehydes; Animals; Antioxidants; Diaphragm; Endotoxins; Histocytochemistry; Immunoblotting; Kinetics; Lipid Peroxidation; Male; Muscle Contraction; Neutrophils; Rats; Rats, Sprague-Dawley; Tyrosine | 1999 |
In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
Topics: Aldehydes; Alzheimer Disease; Analysis of Variance; Biomarkers; DNA Damage; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Histocytochemistry; Humans; Iron; Membrane Proteins; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenylhydrazines; Plaque, Amyloid; Tyrosine | 1999 |
Ceramide prevents motoneuronal cell death through inhibition of oxidative signal.
Topics: Aldehydes; Animals; Antioxidants; Buthionine Sulfoximine; Cell Death; Cell Survival; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Glial Cell Line-Derived Neurotrophic Factor; Glutathione; Immunohistochemistry; Lipid Peroxidation; Motor Neurons; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Tyrosine | 1999 |
Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells.
Topics: Aldehydes; Cell Line; DNA Replication; Humans; Phosphorylation; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Tyrosine; Up-Regulation | 2000 |
Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult.
Topics: 1-Methyl-4-phenylpyridinium; Aldehydes; alpha-Synuclein; Cell Division; Cell Line; Cell Survival; Clone Cells; Culture Media, Serum-Free; Enzyme Inhibitors; Gene Expression; Glutathione; Guanine; Humans; Hydrogen Peroxide; Ketones; Lipid Peroxidation; Mitochondria; Mutation; Nerve Tissue Proteins; Neuroblastoma; Oxidants; Oxidative Stress; Parkinsonian Disorders; Synucleins; Teratocarcinoma; Transfection; Tyrosine | 2001 |
Oxidative stress and disturbed glutamate transport in hereditary nucleotide repair disorders.
Topics: Adolescent; Adult; Aldehydes; Amino Acid Transport System X-AG; ATP-Binding Cassette Transporters; Biological Transport; Child; Cockayne Syndrome; DNA Repair; Female; Glutamic Acid; Glycation End Products, Advanced; Humans; Immunohistochemistry; Male; Neuroglia; Neurons; Oxidative Stress; Proteins; Tyrosine; Xeroderma Pigmentosum | 2001 |
Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.
Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine | 2001 |
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and pro
Topics: Aldehydes; Amino Acid Substitution; Cell Death; Cell Survival; Cross-Linking Reagents; Culture Media, Serum-Free; Genes, bcl-2; Guanine; Humans; Hydrogen Peroxide; Kinetics; Lipid Peroxidation; Motor Neuron Disease; Mutagenesis, Site-Directed; Neuroblastoma; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Teratocarcinoma; Tumor Cells, Cultured; Tyrosine | 2001 |
Oxidative stress and reactive nitrogen species generation during renal ischemia.
Topics: Aldehydes; Animals; Blood Urea Nitrogen; Creatinine; Free Radicals; Glutathione; Kidney; Male; Nitrates; Oxidation-Reduction; Oxidative Stress; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Tyrosine | 2001 |
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Hypoxia; Immunohistochemistry; Ischemia; Nitrogen Oxides; Oxidative Stress; Oxygen; Placenta; Pregnancy; Pregnancy Complications; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tissue Distribution; Tyrosine | 2001 |
Mildly oxidized LDL induces activation of platelet-derived growth factor beta-receptor pathway.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Antioxidants; Aorta; Arteriosclerosis; Autocrine Communication; Cells, Cultured; Ceramides; Chloroquine; Diet, Atherogenic; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Macrolides; Male; Muscle, Smooth, Vascular; Oxidative Stress; Phosphorylation; Rabbits; Reactive Oxygen Species; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sphingomyelins; Tyrosine | 2001 |
Oxidative stress in bacterial meningitis in humans.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldehydes; Allantoin; Ascorbic Acid; Brain; Cysteine Proteinase Inhibitors; Female; Free Radical Scavengers; Glasgow Outcome Scale; Humans; Immunohistochemistry; Male; Meningitis, Bacterial; Middle Aged; Neurons; Oxidative Stress; Reactive Nitrogen Species; Statistics as Topic; Treatment Outcome; Tyrosine; Uric Acid | 2002 |
Peroxynitrite mediated linoleic acid oxidation and tyrosine nitration in the presence of synthetic neuromelanins.
Topics: Aldehydes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dose-Response Relationship, Drug; Hydrogen Peroxide; Linoleic Acid; Melanins; Nitrogen; Oxygen; Peroxynitrous Acid; Tyrosine | 2000 |
Proteasome function and protein oxidation in the aged retina.
Topics: Aging; Aldehydes; Animals; Blotting, Western; Caseins; Chymotrypsin; Cysteine Endopeptidases; Eye Proteins; Male; Multienzyme Complexes; Oxidation-Reduction; Oxidative Stress; Proteasome Endopeptidase Complex; Rats; Rats, Inbred BN; Rats, Inbred F344; Retina; Tyrosine | 2002 |
Amelioration of cisplatin toxicity by a fermented grain food product.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antioxidants; Blood Urea Nitrogen; Cisplatin; Creatinine; Deoxyguanosine; Diet; Edible Grain; Fermentation; Intestines; Kidney; Lipid Peroxidation; Male; Nitrates; Nitrites; Rats; Rats, Inbred F344; Tyrosine; Weight Loss | 2002 |
Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice.
Topics: Alanine Transaminase; Aldehydes; Animals; Aspartate Aminotransferases; Body Weight; Cytochrome P-450 CYP2E1; Endotoxins; Ethanol; Free Radicals; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Peroxynitrite-mediated protein nitration and lipid peroxidation in a mouse model of traumatic brain injury.
Topics: Aldehydes; Animals; Brain; Brain Injuries; Disease Models, Animal; Image Processing, Computer-Assisted; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Nerve Degeneration; Peroxynitrous Acid; Proteins; Time Factors; Tyrosine | 2004 |
Oxidatively damaged proteins of heart mitochondrial electron transport complexes.
Topics: Adenine Nucleotide Translocator 1; Aldehydes; Animals; Cattle; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Intracellular Membranes; Mitochondria, Heart; Oxidation-Reduction; Oxygen Consumption; Porins; Protein Structure, Tertiary; Reactive Oxygen Species; Submitochondrial Particles; Tyrosine; Voltage-Dependent Anion Channels | 2004 |
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
Topics: Aldehydes; Animals; Biomarkers; Body Weight; Carboxylic Acids; Cysteine; Dinitrophenols; Energy Intake; Free Radical Scavengers; Gentamicins; Hydroxyl Radical; Immunohistochemistry; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine; Urine | 2004 |
Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice.
Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Biomarkers; Brain; Cells, Cultured; Disease Models, Animal; Down-Regulation; Glutamate-Ammonia Ligase; Lipid Peroxidation; Memory Disorders; Mice; Mice, Inbred Strains; Neurons; Oligonucleotides, Antisense; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Tyrosine | 2004 |
Mechanisms of apoptosis induced by cisplatin in marginal cells in mouse stria vascularis.
Topics: Aldehydes; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cisplatin; Cytochromes c; Enzyme Activation; Immunohistochemistry; In Situ Nick-End Labeling; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Stria Vascularis; Tyrosine | 2004 |
NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Auditory Threshold; Benzimidazoles; Blotting, Western; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Death; Cell Fractionation; Cochlea; Cyclooxygenase Inhibitors; DNA Replication Timing; Drosophila Proteins; Drug Administration Schedule; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Activation; Hair Cells, Auditory; Hydroxybenzoates; Immunohistochemistry; Immunoprecipitation; Iron Chelating Agents; Kanamycin; Male; Membrane Glycoproteins; Mice; Mice, Inbred CBA; Molecular Chaperones; Nerve Tissue Proteins; NF-kappa B; Phosphorylation; Protective Agents; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Signal Transduction; Synaptotagmin I; Synaptotagmins; Time Factors; Tyrosine | 2005 |
Role of reactive radicals in degeneration of the auditory system of mice following cisplatin treatment.
Topics: Aldehydes; Animals; Antineoplastic Agents; Cisplatin; Cochlea; Free Radicals; Hair Cells, Auditory, Outer; Hydroxyl Radical; Immunohistochemistry; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Spiral Ganglion; Tyrosine | 2004 |
Role of oxidative stress in the pathogenesis of septic ileus in mice.
Topics: Aldehydes; Animals; Antioxidants; Catalase; Disease Models, Animal; Gastric Emptying; Gastrointestinal Transit; Ileus; Immunohistochemistry; Intestinal Mucosa; Lipopolysaccharides; Macrophages; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Sepsis; Superoxide Dismutase; Tyrosine | 2005 |
Role of oxidative stress in paraquat-induced dopaminergic cell degeneration.
Topics: Aldehydes; Analysis of Variance; Animals; Cell Count; Dopamine; Drug Administration Schedule; Ferritins; Herbicides; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Oxidative Stress; Paraquat; Promoter Regions, Genetic; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 2005 |
Nuclear factor {kappa}B inactivation in the rat liver ameliorates short term total warm ischaemia/reperfusion injury.
Topics: Adenoviridae; Aldehydes; Animals; Blotting, Western; Gene Transfer Techniques; Hepatocytes; I-kappa B Proteins; Kupffer Cells; Liver; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Antioxidant treatment normalizes nitric oxide production, renal sodium handling and blood pressure in experimental hyperleptinemia.
Topics: Acetophenones; Aconitate Hydratase; Aldehydes; Animals; Antioxidants; Blood Pressure; Body Weight; Creatine; Cyclic GMP; Cyclic N-Oxides; Drinking; Eating; Hypertension; Isoprostanes; Kidney; Leptin; Male; Malondialdehyde; Natriuresis; Nitric Oxide; Rats; Rats, Wistar; Reactive Nitrogen Species; Sodium; Spin Labels; Tyrosine | 2005 |
Post-exposure treatment attenuates noise-induced hearing loss.
Topics: Aldehydes; Animals; Cochlea; Guinea Pigs; Hearing Loss, Noise-Induced; Immunohistochemistry; Male; Reactive Oxygen Species; Sound; Time Factors; Tyrosine | 2005 |
Exposure to ethanol induces oxidative damage in the pituitary gland.
Topics: Aldehydes; Animals; Apoptosis; Central Nervous System Depressants; Dinitrophenols; Ethanol; Follicle Stimulating Hormone; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Lipid Peroxidation; Luteinizing Hormone; Male; Nucleic Acids; Nucleosides; Oxidation-Reduction; Oxidative Stress; Pituitary Gland; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Testosterone; Tyrosine | 2005 |
Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury.
Topics: Aldehydes; Animals; Blotting, Northern; Blotting, Western; Cardiovascular Diseases; Copper; Diabetes Mellitus, Experimental; Endothelin-1; Glutathione; Immunohistochemistry; Interleukin-6; Iron; Metallothionein; Mice; Mice, Transgenic; Myocardium; Oxidative Stress; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Zinc | 2005 |
Manganese superoxide dismutase and inducible nitric oxide synthase modify early oxidative events in acute adriamycin-induced mitochondrial toxicity.
Topics: Actins; Aldehydes; Animals; Blotting, Southern; Blotting, Western; Doxorubicin; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Mitochondria, Heart; Myocytes, Cardiac; Nitrates; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2005 |
Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Aldehydes; Apoptosis; Cell Death; Cell Line, Tumor; Drug Resistance; Enzyme Inhibitors; Genetic Predisposition to Disease; Glutamic Acid; Guanine; Humans; Hydrogen Peroxide; Mutation; Nerve Degeneration; Neurons; Neurotoxins; Oxidative Stress; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Substantia Nigra; Tyrosine; Ubiquitin-Protein Ligases | 2005 |
Serofendic acid prevents 6-hydroxydopamine-induced nigral neurodegeneration and drug-induced rotational asymmetry in hemi-parkinsonian rats.
Topics: Adrenergic Agents; Aldehydes; alpha-Synuclein; Animals; Behavior, Animal; Blotting, Western; CD11b Antigen; Cell Count; Cell Line; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Functional Laterality; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Male; Neurodegenerative Diseases; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Parkinsonian Disorders; Rats; Rats, Wistar; Reactive Oxygen Species; Rotarod Performance Test; Rotation; Substantia Nigra; Synaptophysin; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 2005 |
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Antipyrine; Brain; Brain Ischemia; Deoxyguanosine; DNA Damage; Edaravone; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Immunoblotting; Immunohistochemistry; Inflammation; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reperfusion Injury; Time Factors; Tyrosine | 2005 |
Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate-salt hypertension.
Topics: Aldehydes; Animals; Blood Pressure; Cardiotonic Agents; Desoxycorticosterone; Heart; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Sodium Chloride; Tyrosine | 2005 |
Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain.
Topics: Aldehydes; Animals; Anions; Antibiotics, Antineoplastic; Blotting, Western; Brain; Doxorubicin; Free Radicals; Glutathione Transferase; Humans; Ions; Lipid Peroxidation; Male; Mice; Multidrug Resistance-Associated Proteins; Oxidation-Reduction; Oxidative Stress; Oxygen; Proteins; Reactive Oxygen Species; Time Factors; Tyrosine | 2005 |
Abnormal development and increased 3-nitrotyrosine in copper-deficient mouse embryos.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Brain; Copper; Deoxyguanosine; DNA Damage; Epithelium; Female; Fetal Development; Glutathione Peroxidase; Growth Inhibitors; Heart Defects, Congenital; Indicators and Reagents; Lipids; Mice; Neural Tube Defects; Peroxynitrous Acid; Pregnancy; Superoxide Dismutase; Superoxides; Tyrosine | 2006 |
Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione.
Topics: Aldehydes; Animals; Antioxidants; Blotting, Western; Buthionine Sulfoximine; Catalysis; Cell Line; Cell Survival; Cyclosporine; Cytochrome P-450 CYP2E1; DNA, Complementary; Endoplasmic Reticulum; Ethanol; Flow Cytometry; Glutathione; Humans; Liver; Liver Diseases, Alcoholic; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondria, Liver; Oxidative Stress; Plasmids; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Time Factors; Transfection; Tyrosine | 2006 |
In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid beta-peptide (1-42)-induced oxidative stress.
Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Brain; Bridged-Ring Compounds; Disease Models, Animal; Free Radicals; Gerbillinae; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Norbornanes; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Synaptosomes; Thiocarbamates; Thiones; Type C Phospholipases; Tyrosine | 2006 |
Markers of oxidative stress in placental villi exposed to ethanol.
Topics: Aldehydes; Biomarkers; Ethanol; Female; Guanosine; Humans; Oxidative Stress; Placenta; Pregnancy; Trophoblasts; Tyrosine | 2006 |
Increased oxidative stress in asymptomatic current chronic smokers and GOLD stage 0 COPD.
Topics: Aged; Aldehydes; Biomarkers; Breath Tests; Female; Humans; Immunohistochemistry; Lactoferrin; Male; Middle Aged; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Smoking; Sputum; Tyrosine | 2006 |
Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase.
Topics: Acetylcholine; Aldehydes; Animals; Aorta, Thoracic; Arthritis, Experimental; Biopterins; Endothelium, Vascular; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Superoxides; Tyrosine; Vasodilation | 2006 |
Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis.
Topics: Aldehydes; Animals; Antipyrine; Apolipoproteins E; Apoptosis; Atherosclerosis; Cells, Cultured; Cholesterol, Dietary; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Endothelial Cells; Free Radical Scavengers; Hydrogen Peroxide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidants; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2007 |
Oxidative imbalance in the aging inner ear.
Topics: Aging; Aldehydes; Animals; Apoptosis Inducing Factor; Biomarkers; Cochlea; Free Radicals; Hair Cells, Auditory; Male; Mice; Mice, Inbred CBA; Nerve Degeneration; Neurons, Afferent; Organ of Corti; Oxidative Stress; Spiral Ganglion; Superoxide Dismutase; Tyrosine | 2007 |
Increasing oxidative damage and loss of mismatch repair enzymes during breast carcinogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Aldehydes; Base Pair Mismatch; Breast Neoplasms; Carrier Proteins; Deoxyguanosine; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Middle Aged; Nuclear Proteins; Oxidative Stress; Tyrosine | 2006 |
Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy.
Topics: Aldehydes; Animals; Antioxidants; Bisoprolol; Blood Pressure; Body Weight; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Echocardiography; Fibrosis; Glutathione; Heart Failure; Heart Rate; Interleukin-1; Isoenzymes; Male; NADPH Oxidases; Organ Size; Oxidative Stress; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine; Ventricular Function, Left | 2006 |
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease.
Topics: Aldehydes; Alzheimer Disease; Animals; Antioxidants; Behavior Therapy; Behavior, Animal; Brain; Disease Models, Animal; Dogs; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Glutathione Transferase; Heme Oxygenase-1; Proteomics; Superoxide Dismutase; Tyrosine | 2008 |
Oxidative and nitrosative stress in trichloroethene-mediated autoimmune response.
Topics: Aldehydes; Animals; Autoantibodies; Environmental Pollutants; Female; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Mice, Inbred MRL lpr; Nitric Oxide Synthase Type II; Ovalbumin; Oxidative Stress; Solvents; Trichloroethylene; Tyrosine | 2007 |
Role of peroxynitrite in secondary oxidative damage after spinal cord injury.
Topics: Aldehydes; Animals; Biomarkers; Calcium Signaling; Calpain; Disease Progression; Female; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Nerve Degeneration; Nitric Oxide; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spectrin; Spinal Cord Injuries; Time Factors; Tyrosine; Up-Regulation | 2007 |
Role of oxidative stress on pathogenesis of hypertensive cerebrovascular lesions.
Topics: Aldehydes; Animals; Arterioles; Brain; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Disease Models, Animal; Endothelium, Vascular; Hypertension; Intracranial Arterial Diseases; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroblue Tetrazolium; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine; Up-Regulation | 2007 |
Glyceryl trinitrate inhibits hypoxia/reoxygenation-induced apoptosis in the syncytiotrophoblast of the human placenta: therapeutic implications for preeclampsia.
Topics: Aldehydes; Apoptosis; Blotting, Western; Caspase 3; Collagen Type XI; Female; Humans; Hypoxia; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron, Transmission; Nitroglycerin; Organ Culture Techniques; Pre-Eclampsia; Pregnancy; Reperfusion Injury; Tocolytic Agents; Trophoblasts; Tyrosine | 2007 |
Temporal relationship of peroxynitrite-induced oxidative damage, calpain-mediated cytoskeletal degradation and neurodegeneration after traumatic brain injury.
Topics: Aldehydes; Animals; Brain; Brain Injuries; Calcium; Calpain; Cerebral Cortex; Cytoskeleton; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Oxidative Stress; Peroxynitrous Acid; Spectrin; Time Factors; Tissue Distribution; Tyrosine | 2007 |
Difluoromethylornithine decreases long-lasting protein oxidation induced by neonatal ethanol exposure in the hippocampus of adolescent rats.
Topics: Aldehydes; Animals; Animals, Newborn; Biogenic Polyamines; Brain Chemistry; Central Nervous System Depressants; Eflornithine; Enzyme Inhibitors; Ethanol; Hippocampus; Male; Nerve Tissue Proteins; Ornithine Decarboxylase Inhibitors; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tyrosine | 2007 |
Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers.
Topics: Aldehydes; Animals; Cell Respiration; Cerebral Cortex; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Transport Complex I; Free Radical Scavengers; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mitochondria; Molsidomine; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Penicillamine; Peroxynitrous Acid; Protein Carbonylation; Spin Labels; Tyrosine | 2007 |
Temporal characterization of mitochondrial bioenergetics after spinal cord injury.
Topics: Aldehydes; Animals; Disease Models, Animal; Disease Progression; Energy Metabolism; Female; Free Radicals; Lipid Peroxidation; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spinal Cord; Spinal Cord Injuries; Time Factors; Tyrosine | 2007 |
Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Brain Injuries; Cyclooxygenase 2; Encephalitis; Fenofibrate; Glutathione; Male; Matrix Metalloproteinase 9; Nitric Oxide Synthase Type II; Oxidative Stress; PPAR alpha; Rats; Rats, Sprague-Dawley; Recovery of Function; Treatment Outcome; Tyrosine | 2007 |
Oxidative stress is related to the formation of Antoni B patterns and eosinophilic hyaline droplets in schwannomas.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Apolipoproteins D; Autophagy; Caspase 3; Deoxyguanosine; Female; Humans; Hyalin; Immunohistochemistry; Inclusion Bodies; Male; Middle Aged; Neurilemmoma; Nitric Oxide Synthase Type II; Oxidative Stress; Tyrosine | 2007 |
Aging influences multiple indices of oxidative stress in the heart of the Fischer 344/NNia x Brown Norway/BiNia rat.
Topics: Aging; Aldehydes; Analysis of Variance; Animals; Blood Pressure; Female; Heart; Heat-Shock Proteins; Immunoblotting; Immunohistochemistry; Male; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Myocardium; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred BN; Rats, Inbred F344; Reactive Oxygen Species; Regression Analysis; Signal Transduction; Superoxides; Tyrosine | 2007 |
Thioredoxin may exert a protective effect against tissue damage caused by oxidative stress in salivary glands of patients with Sjögren's syndrome.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aldehydes; Antioxidants; Apoptosis; Biomarkers; Cysteine Proteinase Inhibitors; Deoxyguanosine; Female; Humans; Hydrogen Peroxide; Interferon-gamma; Interleukin-6; Middle Aged; Oxidants; Oxidative Stress; Saliva; Salivary Glands; Sjogren's Syndrome; Thioredoxins; Tyrosine | 2007 |
Oxidative modifications of cardiac mitochondria and inhibition of cytochrome c oxidase activity by 4-hydroxynonenal.
Topics: Aldehydes; Animals; Dose-Response Relationship, Drug; Electron Transport Complex IV; Lipid Peroxidation; Male; Membrane Lipids; Mitochondria, Heart; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine | 2007 |
Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog.
Topics: Acute Disease; Aldehydes; Animals; Biomarkers; Brain Injuries; Cyclosporine; Dose-Response Relationship, Drug; Immunoblotting; Lipid Peroxidation; Male; Mice; Mitochondrial Diseases; Oxidative Stress; Oxygen Consumption; Structure-Activity Relationship; Tyrosine | 2008 |
X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidants.
Topics: Aldehydes; Animals; Antioxidants; Brain; Brain Ischemia; Cytochromes c; Female; Gene Expression; Hypoxia, Brain; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Oxidative Stress; Tyrosine; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2007 |
Selective iNOS inhibition reduces renal damage induced by cisplatin.
Topics: Aldehydes; Amidines; Animals; Antineoplastic Agents; Benzylamines; Cisplatin; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Tyrosine | 2008 |
A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Brain; Cell Respiration; Cells, Cultured; Disease Models, Animal; Humans; Membrane Potential, Mitochondrial; Metalloporphyrins; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Mutation; Neurons; Oxidative Stress; Presenilin-1; Protein Carbonylation; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine | 2008 |
Alcohol-induced oxidative stress in the liver: in vivo measurements.
Topics: Aldehydes; Animals; Biomarkers; Disease Models, Animal; Immunohistochemistry; Lipopolysaccharides; Liver; Liver Diseases, Alcoholic; Mice; Mice, Transgenic; Oxidative Stress; Photomicrography; Proteins; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Reproducibility of Results; Signal Processing, Computer-Assisted; Specimen Handling; Tyrosine | 2008 |
Aging results in increased autophagy of mitochondria and protein nitration in rat hepatocytes following heat stress.
Topics: Aging; Aldehydes; Animals; Autophagy; Energy Metabolism; Heating; Hepatocytes; Immunohistochemistry; Lipid Peroxidation; Male; Microscopy, Electron, Transmission; Mitochondria; Oxidative Stress; Peroxisomes; Proteins; Rats; Rats, Inbred F344; Reactive Nitrogen Species; Reactive Oxygen Species; Tyrosine | 2008 |
Changes in transient receptor potential vanilloid (TRPV) 1, 2, 3 and 4 expression in mouse inner ear following gentamicin challenge.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Brain-Derived Neurotrophic Factor; Calcium Channels; Ear, Inner; Ganglia, Spinal; Gentamicins; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Mice; Mice, Inbred CBA; Microscopy, Fluorescence; Nerve Fibers; Organ of Corti; Semicircular Ducts; Sensory Receptor Cells; Spiral Ganglion; Stria Vascularis; Trigeminal Ganglion; TRPV Cation Channels; Tyrosine; Vestibular Nerve | 2009 |
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia.
Topics: Aldehydes; Angiotensin II; Animals; Antioxidants; Arterioles; Body Weight; Cyclic N-Oxides; Disease Models, Animal; Glomerular Filtration Rate; Hypertension, Renal; Hyperuricemia; Kidney Glomerulus; Male; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Oxonic Acid; Rats; Rats, Sprague-Dawley; Renal Circulation; Spin Labels; Superoxides; Tyrosine | 2008 |
Differential effects of the mitochondrial uncoupling agent, 2,4-dinitrophenol, or the nitroxide antioxidant, Tempol, on synaptic or nonsynaptic mitochondria after spinal cord injury.
Topics: 2,4-Dinitrophenol; Aldehydes; Animals; Antioxidants; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Electron Transport Complex I; Energy Metabolism; Female; Mitochondria; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Spin Labels; Spinal Cord Diseases; Time Factors; Tyrosine; Uncoupling Agents | 2009 |
Treatment with pyrrolidine dithiocarbamate improves proteinuria, oxidative stress, and glomerular hypertension in overload proteinuria.
Topics: Aldehydes; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood Pressure; Glomerular Filtration Rate; Glutathione Reductase; Hypertension, Renal; Kidney; Kidney Glomerulus; Male; Nitric Oxide Synthase Type II; Organ Size; Oxidative Stress; Peroxidases; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Superoxide Dismutase; Thiocarbamates; Transcription Factor RelA; Tyrosine | 2008 |
Carbonic anhydrase III and four-and-a-half LIM protein 1 are preferentially oxidized with muscle unloading.
Topics: Age Factors; Aging; Aldehydes; Animals; Carbonic Anhydrase III; Hindlimb Suspension; LIM Domain Proteins; Male; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Proteomics; Rats; Rats, Inbred F344; Time Factors; Tyrosine | 2008 |
Proteomic analysis of brain protein expression levels in NF-kappabeta p50 -/- homozygous knockout mice.
Topics: Aldehydes; Animals; Brain; Electrophoresis, Gel, Two-Dimensional; Image Processing, Computer-Assisted; Male; Mass Spectrometry; Mice; Mice, Knockout; NF-kappa B p50 Subunit; Oxidative Stress; Proteomics; Tyrosine | 2008 |
Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity.
Topics: Acrolein; Aldehydes; Analysis of Variance; Blotting, Western; Cell Line, Tumor; Cell Survival; Cytotoxins; Flavonoids; Free Radicals; Glutathione; Humans; Lipid Peroxidation; Luminescence; NADPH Oxidases; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Protein Carbonylation; Tyrosine | 2008 |
NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart.
Topics: Acetophenones; Acetylcholine; Aldehydes; Animals; Antioxidants; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Heart Failure; Hemodynamics; Male; NADPH Oxidases; Oxidative Stress; RNA, Messenger; Superoxides; Tyrosine; Up-Regulation; Vasodilation; Vasodilator Agents | 2009 |
L-Carnitine in the lipid and protein protection against ethanol-induced oxidative stress.
Topics: Aldehydes; Animals; Antioxidants; Carnitine; Ethanol; Glutathione; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Proteins; Rats; Rats, Wistar; Tryptophan; Tyrosine; Vitamin E | 2009 |
Sepiapterin decreases acute rejection and apoptosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization.
Topics: Aldehydes; Animals; Apoptosis; Arginase; Biopterins; Cyclosporine; Cytokines; Echocardiography; Gene Expression; Graft Rejection; GTP Cyclohydrolase; Heart Transplantation; Heart Ventricles; Immunosuppressive Agents; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Processing, Post-Translational; Pterins; Rats; Rats, Inbred Lew; Rats, Inbred WF; Transplantation, Homologous; Transplantation, Isogeneic; Tyrosine | 2009 |
Coupled calcium and zinc dyshomeostasis and oxidative stress in cardiac myocytes and mitochondria of rats with chronic aldosteronism.
Topics: Aldehydes; Aldosterone; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Disease Models, Animal; Glutathione Peroxidase; Homeostasis; Hydrogen Peroxide; Hyperaldosteronism; Male; Metallothionein; Mineralocorticoid Receptor Antagonists; Mitochondria, Heart; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spironolactone; Superoxide Dismutase; Tyrosine; Zinc | 2009 |
Detection of 4-hydroxy-2-nonenal- and 3-nitrotyrosine-modified proteins using a proteomics approach.
Topics: Aldehydes; Electrophoresis, Gel, Two-Dimensional; Humans; Isoelectric Focusing; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Proteins; Proteomics; Tyrosine | 2009 |
Methylamine dichloramine may play a role in the process of colorectal disease through architectural and oxidative changes in crypts in mice.
Topics: Aldehydes; Animals; Chloramines; Colon; Colonic Neoplasms; Hemoglobins; Hemolysis; Hydrogen Peroxide; Hypochlorous Acid; Immunohistochemistry; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Neutrophil Activation; Oxidation-Reduction; Sheep; Tyrosine | 2009 |
Temporal and spatial dynamics of peroxynitrite-induced oxidative damage after spinal cord contusion injury.
Topics: Aldehydes; Animals; Female; Immunohistochemistry; Lipid Peroxidation; Neurons; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Thoracic Vertebrae; Time Factors; Tyrosine | 2009 |
Hypothermic inhibition of apoptotic pathways for combined neurotoxicity of iron and ascorbic acid in differentiated PC12 cells: reduction of oxidative stress and maintenance of the glutathione redox state.
Topics: Aldehydes; Animals; Apoptosis; Apoptosis Regulatory Proteins; Ascorbic Acid; Biomarkers; Body Temperature; Drug Synergism; Glutathione; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Iron; Membrane Potentials; Neurons; Neurotoxins; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Proto-Oncogene Proteins c-akt; Rats; Temperature; Tyrosine | 2009 |
Supplementary catechins attenuate cooking-oil-fumes-induced oxidative stress in rat lung.
Topics: Acute Lung Injury; Aldehydes; Animals; Apoptosis; bcl-2-Associated X Protein; Catechin; Cooking; Dietary Supplements; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Oils; Oxidative Stress; Pneumonia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors; Tyrosine | 2009 |
Attenuation of diabetes-induced renal dysfunction by multiple exposures to low-dose radiation is associated with the suppression of systemic and renal inflammation.
Topics: Albuminuria; Aldehydes; Animals; Blotting, Western; Chemokine CCL2; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Intercellular Adhesion Molecule-1; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Nephritis; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serpin E2; Serpins; Tumor Necrosis Factor-alpha; Tyrosine | 2009 |
In utero exposure to benzene disrupts fetal hematopoietic progenitor cell growth via reactive oxygen species.
Topics: Aldehydes; Animals; Antioxidants; Benzene; Blotting, Western; Catalase; Cell Proliferation; Cells, Cultured; Colony-Forming Units Assay; Environmental Pollutants; Female; Fetal Stem Cells; Flow Cytometry; Gestational Age; Glutathione Disulfide; Hematopoietic Stem Cells; I-kappa B Proteins; Liver; Maternal Exposure; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Polyethylene Glycols; Pregnancy; Proto-Oncogene Proteins c-kit; Reactive Oxygen Species; Time Factors; Tyrosine | 2010 |
Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.
Topics: Aging; Aldehydes; Animals; Calcium Channels; Ear, Inner; Glucuronidase; Klotho Proteins; Mice; Mice, Inbred CBA; Microscopy; Superoxide Dismutase; TRPV Cation Channels; Tyrosine | 2009 |
Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid.
Topics: Aldehydes; Animals; Animals, Newborn; Cerebral Cortex; Convulsants; Disease Models, Animal; Down-Regulation; Electron Transport Complex I; Energy Metabolism; Epilepsy; Excitatory Amino Acid Agonists; Free Radical Scavengers; Homocysteine; Male; Metabolic Networks and Pathways; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Rats; Rats, Wistar; Seizures; Survival Rate; Time Factors; Tyrosine | 2010 |
Simvastatin reduces mortality and hepatic injury after hemorrhage/resuscitation in rats.
Topics: Actins; Aldehydes; Animals; Apoptosis; Cytoskeleton; DNA Fragmentation; Hemodynamics; Hemorrhage; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Lipid Peroxidation; Liver; Male; Neutrophils; Nitric Oxide Synthase Type III; Rats; Resuscitation; Simvastatin; Tyrosine | 2010 |
Oxidative stress in the progression of Alzheimer disease in the frontal cortex.
Topics: Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Antioxidants; Biomarkers; Disease Progression; Female; Frontal Lobe; Humans; Male; Mental Status Schedule; Oxidative Stress; Protein Carbonylation; Synapses; Thiobarbituric Acid Reactive Substances; Tissue Distribution; Tyrosine | 2010 |
Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration.
Topics: Aldehydes; Animals; Choroidal Neovascularization; Coloring Agents; Disease Models, Animal; Female; Fluorescein Angiography; Indocyanine Green; Light; Oxidative Stress; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Rats, Wistar; Retina; Retinal Degeneration; Tomography, Optical Coherence; Tyrosine | 2010 |
Liposomal doxorubicin increases radiofrequency ablation-induced tumor destruction by increasing cellular oxidative and nitrative stress and accelerating apoptotic pathways.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Aldehydes; Animals; Apoptosis; Caspase 3; Catheter Ablation; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Female; Histones; HSP70 Heat-Shock Proteins; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Oxidative Stress; Rats; Rats, Inbred F344; Tyrosine | 2010 |
Science to practice: will randomized prospective clinical trials be necessary for RF ablation of large liver tumors with liposomal doxorubicin?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenocarcinoma; Aldehydes; Animals; Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Catheter Ablation; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Histones; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Oxidative Stress; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Tyrosine | 2010 |
PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload.
Topics: Aldehydes; Animals; Antioxidants; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocardial Contraction; Myocardium; Nitroso Compounds; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Superoxide Dismutase; Systole; Thioredoxins; Trans-Activators; Transcription Factors; Tyrosine | 2010 |
Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model.
Topics: Administration, Inhalation; Aldehydes; Animals; Antioxidants; Aquaporin 4; Brain Damage, Chronic; Cerebral Hemorrhage; Disease Progression; Drug Evaluation, Preclinical; Extracellular Matrix Proteins; Glucose; Hydrogen; Hyperglycemia; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Tyrosine | 2010 |
Suppression of hepatic oxidative events and regulation of eNOS expression in the liver by naringenin in fructose-administered rats.
Topics: 2,4-Dinitrophenol; Aldehydes; Animals; Antioxidants; Apoptosis; Blood Glucose; Diet; Flavanones; Fructose; Hepatocytes; Insulin; Insulin Resistance; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Tyrosine | 2010 |
Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain.
Topics: Acetylcarnitine; Aldehydes; Animals; Astrocytes; Brain; Ethanol; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Synaptic Transmission; Tyrosine | 2010 |
Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse.
Topics: Aldehydes; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Azoles; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Isoindoles; Kidney; Male; Mice; Mice, Knockout; Organoselenium Compounds; Reactive Oxygen Species; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2010 |
Effect of endurance exercise training on oxidative stress in spontaneously hypertensive rats (SHR) after emergence of hypertension.
Topics: Age Factors; Aldehydes; Animals; Aorta; Blood Pressure; Coronary Artery Disease; Fluoroimmunoassay; Hypertension; Motor Activity; Nitric Oxide; Oxidative Stress; Physical Conditioning, Animal; Physical Endurance; Rats; Rats, Inbred SHR; Superoxide Dismutase; Superoxides; Tyrosine | 2010 |
Role of the inducible nitric oxide synthase in the onset of fructose-induced steatosis in mice.
Topics: Aldehydes; Animals; Cells, Cultured; Coculture Techniques; Endotoxins; Fatty Liver; Fructokinases; Fructose; Glutathione; I-kappa B Proteins; Insulin Resistance; Kupffer Cells; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; NF-kappa B; Nitric Oxide Synthase Type II; Organ Size; Toll-Like Receptor 4; Transcription, Genetic; Triglycerides; Tumor Necrosis Factor-alpha; Tyrosine; Weight Gain | 2011 |
Glutamate transporter type 3 knockout reduces brain tolerance to focal brain ischemia in mice.
Topics: Aldehydes; Animals; Blotting, Western; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Transporter 3; Glutathione; Male; Mice; Mice, Knockout; Tyrosine | 2011 |
Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Blotting, Western; Brain; Cerebellum; Cognitive Dysfunction; Female; Heme Oxygenase (Decyclizing); Hippocampus; Homeostasis; Humans; Immunoprecipitation; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Protein Carbonylation; Reactive Nitrogen Species; Tyrosine | 2011 |
Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes.
Topics: Alanine Transaminase; Aldehydes; Animals; Anti-Inflammatory Agents; Fatty Liver; Inflammation; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NADPH Oxidases; Nitric Oxide Synthase Type II; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peroxidase; Plant Extracts; Reactive Oxygen Species; Stress, Physiological; Tea; Tyrosine | 2012 |
Plant polyphenols attenuate hepatic injury after hemorrhage/resuscitation by inhibition of apoptosis, oxidative stress, and inflammation via NF-kappaB in rats.
Topics: Acute Disease; Alanine Transaminase; Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Female; Gene Expression Regulation; Hemorrhage; Inflammation; Interleukin-6; L-Lactate Dehydrogenase; Liver; NF-kappa B; Oxidative Stress; Plant Extracts; Polyphenols; Rats; Rats, Inbred Lew; Resuscitation; RNA; Tea; Tyrosine | 2012 |
Human internal thoracic artery grafts exhibit severe morphological and functional damage and spasmic vasomotion due to oxidative stress.
Topics: Aged; Aldehydes; Analysis of Variance; Female; Histological Techniques; Humans; Immunohistochemistry; Male; Mammary Arteries; Middle Aged; Oxidative Stress; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Spasm; Tyrosine; Vascular Grafting; Vasomotor System | 2011 |
Orally active multi-functional antioxidants are neuroprotective in a rat model of light-induced retinal damage.
Topics: Aldehydes; Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Electroretinography; Enzyme-Linked Immunosorbent Assay; Light; Male; Oxidative Stress; Rats; Rats, Wistar; Retina; Sulfonamides; Thioredoxins; Tyrosine | 2011 |
Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2.
Topics: Acetyl-CoA Carboxylase; Aldehydes; AMP-Activated Protein Kinases; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Berberine; Blood Glucose; Cholesterol; Enzyme Activation; Humans; Intercellular Adhesion Molecule-1; Ion Channels; Mice; Mitochondrial Proteins; Phosphorylation; Plaque, Atherosclerotic; Protein Transport; Serine; Threonine; Transcription, Genetic; Triglycerides; Tyrosine; Uncoupling Protein 2; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2011 |
Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.
Topics: Acute Disease; Aldehydes; Analgesics, Opioid; Animals; Antioxidants; Blood-Brain Barrier; Capillary Permeability; Carbon Radioisotopes; Codeine; Cyclic N-Oxides; Cysteine Proteinase Inhibitors; Hyperalgesia; Male; Membrane Proteins; Neuralgia; Neuritis; Occludin; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spin Labels; Sucrose; Tight Junctions; Tyrosine; Xenobiotics | 2012 |
Thiazolidinedione treatment decreases oxidative stress in spontaneously hypertensive heart failure rats through attenuation of inducible nitric oxide synthase-mediated lipid radical formation.
Topics: Aldehydes; Animals; Body Composition; Free Radicals; Glucose Intolerance; Heart Failure; Hypertension; Insulin Resistance; Lipid Peroxidation; Liver; Male; Muscle, Skeletal; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiazolidinediones; Tyrosine | 2012 |
δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats.
Topics: Aldehydes; alpha-Tocopherol; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Cyclin D1; Dinoprost; Dinoprostone; gamma-Tocopherol; Immunohistochemistry; Male; Models, Chemical; Rats; Rats, Inbred F344; Tocopherols; Tyrosine | 2012 |
Evidence of oxidative injury of the spinal cord in 2 horses with equine degenerative myeloencephalopathy.
Topics: Aldehydes; Animals; Ataxia; Brain Diseases; Central Nervous System; Female; Horse Diseases; Horses; Immunohistochemistry; Neurodegenerative Diseases; Oxidative Stress; Spinal Cord Diseases; Tyrosine; Vitamin E; Vitamin E Deficiency | 2012 |
Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis.
Topics: Aldehydes; Animals; Apoptosis; Blood Glucose; Blotting, Western; Cataract; Cattle; Diabetes Complications; Extracellular Signal-Regulated MAP Kinases; Fasting; Guanidines; In Situ Nick-End Labeling; Lens, Crystalline; Male; Nitrosation; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Retina; Sodium-Hydrogen Exchangers; Sulfones; Tyrosine | 2012 |
Acute ethanol gavage attenuates hemorrhage/resuscitation-induced hepatic oxidative stress in rats.
Topics: Aldehydes; Animals; bcl-2-Associated X Protein; Caspase 8; Ethanol; Female; Hemorrhage; Liver; Nitric Oxide Synthase Type II; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Resuscitation; Tyrosine | 2012 |
Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.
Topics: Aldehydes; Anilides; Cells, Cultured; Cysteine Proteinase Inhibitors; Electrophoretic Mobility Shift Assay; Humans; Lactones; Leupeptins; Oxazoles; Oxidative Stress; PPAR alpha; Retinal Pigment Epithelium; Tyrosine; Vitamin K 3 | 2012 |
Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes.
Topics: Aldehydes; Amino Acid Sequence; Cells, Cultured; Dose-Response Relationship, Radiation; Erythrocyte Membrane; Erythrocytes; Gamma Rays; Hemoglobins; Hemolysis; Humans; Hydrogen Peroxide; Methionine; Molecular Sequence Data; Nitrites; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Tyrosine | 2013 |
Retinal cell death induced by TRPV1 activation involves NMDA signaling and upregulation of nitric oxide synthases.
Topics: Aldehydes; Animals; Cell Death; DNA Fragmentation; Ion Channel Gating; Lipid Peroxidation; Male; N-Methylaspartate; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrosation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Signal Transduction; TRPV Cation Channels; Tyrosine; Up-Regulation | 2013 |
Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone.
Topics: Aldehydes; Analysis of Variance; Animals; Blood-Brain Barrier; Cell Count; Disease Models, Animal; Hydrogen Peroxide; Locomotion; Male; Metalloporphyrins; Methylprednisolone; Microdialysis; Nervous System Diseases; Neuroprotective Agents; Oxidative Stress; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Spinal Cord Injuries; Time Factors; Tyrosine | 2013 |
Age- and diabetes-induced regulation of oxidative protein modification in rat brain and peripheral tissues: consequences of treatment with antioxidant pyridoindole.
Topics: Aging; Aldehydes; Animals; Antioxidants; Cerebral Cortex; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Heart Ventricles; Indoles; Kidney; Lens, Crystalline; Liver; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Pyridines; Rats; Rats, Wistar; Tyrosine | 2013 |
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazolidines; Tyrosine | 2013 |
Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats.
Topics: Aldehydes; Animals; Arterioles; Behavior, Animal; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glycation End Products, Advanced; Guanidines; Male; Nerve Fibers; Nitrates; Pain Measurement; Pyruvaldehyde; Rats; Rats, Wistar; Reduced Folate Carrier Protein; Sciatic Nerve; Skin; Sulfones; Superoxides; Tyrosine | 2013 |
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.
Topics: Aldehydes; Angiotensin II Type 1 Receptor Blockers; Animals; Catalase; Citrate (si)-Synthase; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Imidazoles; Insulin Resistance; Male; Membrane Glycoproteins; Mitochondria, Heart; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; NF-E2-Related Factor 2; Obesity; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred OLETF; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazoles; Time Factors; Tyrosine | 2013 |
Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Inhalation; Aldehydes; Animals; Antioxidants; Cardiotonic Agents; Deoxyguanosine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Gases; Hydrogen; Immunohistochemistry; Inhalation; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; Nitric Oxide; Oxidative Stress; Receptors, Cell Surface; Time Factors; Tyrosine; Ventricular Function, Left | 2013 |
In vivo detection of free radicals in mouse septic encephalopathy using molecular MRI and immuno-spin trapping.
Topics: Aldehydes; Animals; Astrocytes; Brain; Cell Line; Cyclic N-Oxides; Free Radicals; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Oxidative Stress; Sepsis-Associated Encephalopathy; Spin Labels; Spin Trapping; Tyrosine | 2013 |
Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis.
Topics: Aldehydes; Animals; Apoptosis; Autophagy; Berberine; Blood Urea Nitrogen; Cisplatin; Creatinine; Cytochrome P-450 CYP2E1; Kidney; Male; Mice; Mice, Inbred BALB C; Nephritis; Oxidative Stress; Protective Agents; Tyrosine | 2013 |
Increased levels of the oxidative stress marker, nitrotyrosine in patients with provocation test-induced coronary vasospasm.
Topics: Acetylcholine; Aged; Aldehydes; Biomarkers; Coronary Vasospasm; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Oxidative Stress; Tyrosine | 2014 |
Neuroprotective effects of tibolone against oxidative stress induced by ozone exposure.
Topics: Aldehydes; Animals; Atmosphere Exposure Chambers; Behavior, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Hippocampus; Learning; Lipid Peroxidation; Male; Nerve Tissue Proteins; Neuroprotective Agents; Norpregnenes; Oxidative Stress; Ozone; Pyramidal Cells; Random Allocation; Rats; Rats, Wistar; Tyrosine | 2014 |
Oxidative stress in older patients with bipolar disorder.
Topics: Aged; Aldehydes; Bipolar Disorder; Case-Control Studies; Female; Humans; Lipid Peroxides; Male; Middle Aged; Oxidative Stress; Protein Carbonylation; Tyrosine | 2015 |
Deletion of metallothionein exacerbates intermittent hypoxia-induced oxidative and inflammatory injury in aorta.
Topics: Aldehydes; Animals; Aorta; Apoptosis; Connective Tissue Growth Factor; Hypoxia; Metallothionein; Mice; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
Evidence of Oxidative Injury in Pigs With Melanosis Coli.
Topics: Aldehydes; Animals; Colon; Colonic Diseases; Female; Macrophages; Malondialdehyde; Melanosis; Oxidative Stress; Swine; Tyrosine | 2015 |
Trans-sodium crocetinate provides neuroprotection against cerebral ischemia and reperfusion in obese mice.
Topics: Aldehydes; Analysis of Variance; Animals; Brain; Brain Ischemia; Carotenoids; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Matrix Metalloproteinases; Mice; Nervous System Diseases; Neuroprotective Agents; Obesity; Oxidative Stress; Reperfusion; Tyrosine; Vitamin A | 2015 |
Autophagy attenuates noise-induced hearing loss by reducing oxidative stress.
Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Autophagy; Hair Cells, Auditory, Outer; Hearing Loss, Noise-Induced; Male; Mice; Microtubule-Associated Proteins; Oxidative Stress; Sirolimus; Tyrosine | 2015 |
Effect of diet-induced obesity or type 1 or type 2 diabetes on corneal nerves and peripheral neuropathy in C57Bl/6J mice.
Topics: Aldehydes; Animals; Cornea; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diet; Ganglia, Spinal; Glucose Tolerance Test; Mice; Mice, Inbred C57BL; Neural Conduction; Obesity; Tyrosine | 2015 |
Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock.
Topics: Acute Kidney Injury; Aging; Aldehydes; Animals; Antioxidants; Citrate (si)-Synthase; Hemorrhage; Kidney; Male; Mitochondria; Oxidative Stress; Rats; Rats, Long-Evans; Reactive Oxygen Species; Resuscitation; Resveratrol; Shock, Hemorrhagic; Stilbenes; Tyrosine | 2015 |
The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania.
Topics: Acetylcysteine; Aldehydes; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain; Deferoxamine; Disease Models, Animal; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Sleep Deprivation; Tyrosine | 2015 |
The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in mice.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Creatine; Creatine Kinase; Dexamethasone; Drugs, Chinese Herbal; Fibrosis; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Muscle Proteins; Muscle Strength; Muscle Tonus; Muscle, Skeletal; Muscular Atrophy; Myostatin; Nitric Oxide Synthase Type II; Oxymetholone; Phosphatidylinositol 3-Kinase; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A1; RNA, Messenger; Schisandra; Sirtuin 1; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; TRPV Cation Channels; Tyrosine; Ubiquitin-Protein Ligases | 2015 |
Oxidative/Nitrative Stress and Inflammation Drive Progression of Doxorubicin-Induced Renal Fibrosis in Rats as Revealed by Comparing a Normal and a Fibrosis-Resistant Rat Strain.
Topics: Aldehydes; Animals; Body Weight; Chemokine CCL2; Connective Tissue Growth Factor; Disease Progression; Disease Resistance; Dose-Response Relationship, Drug; Doxorubicin; Fibrosis; Kidney; Male; Membrane Proteins; Oxidative Stress; Proteinuria; Rats; Reactive Nitrogen Species; Species Specificity; Transforming Growth Factor beta1; Tyrosine | 2015 |
The Effects of Xanthine Oxidoreductase Inhibitors on Oxidative Stress Markers following Global Brain Ischemia Reperfusion Injury in C57BL/6 Mice.
Topics: Aldehydes; Allopurinol; Animals; Biomarkers; Brain; Brain Ischemia; Disease Models, Animal; Interleukin-1beta; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Uric Acid; Xanthine Dehydrogenase | 2015 |
Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats.
Topics: Adrenal Glands; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Eplerenone; Heart Diseases; Hypertension; Lipid Peroxidation; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction; Spironolactone; Time Factors; Tyrosine | 2015 |
Intraventricular apolipoprotein ApoJ infusion acts protectively in Traumatic Brain Injury.
Topics: Aldehydes; Animals; Behavior, Animal; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cerebral Cortex; Clusterin; Disease Models, Animal; Infusions, Intraventricular; Male; Mice, Inbred C57BL; Neuroprotective Agents; Tyrosine | 2016 |
Cyanidin-3-glucoside and its phenolic acid metabolites attenuate visible light-induced retinal degeneration in vivo via activation of Nrf2/HO-1 pathway and NF-κB suppression.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anthocyanins; Antioxidants; Apoptosis; Coumaric Acids; Cytokines; Deoxyguanosine; Glucosides; Heme Oxygenase-1; Hydroxybenzoates; In Situ Nick-End Labeling; Light; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rabbits; Retina; Retinal Degeneration; Signal Transduction; Tyrosine; Up-Regulation | 2016 |
Primary blast causes mild, moderate, severe and lethal TBI with increasing blast overpressures: Experimental rat injury model.
Topics: Aldehydes; Animals; Blast Injuries; Blood-Brain Barrier; Bradycardia; Brain; Brain Injuries, Traumatic; Explosions; Lung Injury; Male; Microvessels; NADPH Oxidases; Nitric Oxide Synthase Type II; Nitrosative Stress; Rats, Sprague-Dawley; Tyrosine | 2016 |
Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice.
Topics: Aldehydes; Animals; Aorta; Aortic Diseases; Apoptosis; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Fibroblast Growth Factors; Fibrosis; Gene Deletion; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Oxidative Stress; Phenotype; Signal Transduction; Time Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Remodeling | 2015 |
Proteomic analysis of 4-hydroxynonenal and nitrotyrosine modified proteins in RTT fibroblasts.
Topics: Aldehydes; Blotting, Western; Case-Control Studies; Cells, Cultured; Female; Fibroblasts; Humans; Proteins; Proteome; Proteomics; Real-Time Polymerase Chain Reaction; Rett Syndrome; Tyrosine | 2016 |
Extracellular Signal-Regulated Kinase/Nuclear Factor-Erythroid2-like2/Heme Oxygenase-1 Pathway-Mediated Mitophagy Alleviates Traumatic Brain Injury-Induced Intestinal Mucosa Damage and Epithelial Barrier Dysfunction.
Topics: Aldehydes; Animals; Brain Injuries, Traumatic; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Intestinal Mucosa; Male; Mitophagy; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrosine | 2017 |
Effects of epidural compression on stellate neurons and thalamocortical afferent fibers in the rat primary somatosensory cortex.
Topics: Acetophenones; Afferent Pathways; Aldehydes; Animals; Antioxidants; Ascorbic Acid; Biotin; Brain Injuries; Dendrites; Dextrans; Disease Models, Animal; Electron Transport Complex IV; Epidural Space; Functional Laterality; Male; Neurons; Oxidative Stress; Rats; Somatosensory Cortex; Thalamus; Time Factors; Tyrosine | 2017 |
Genipin attenuates cisplatin-induced nephrotoxicity by counteracting oxidative stress, inflammation, and apoptosis.
Topics: Aldehydes; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Caspase 3; Caspase 7; Cell Line, Tumor; Cisplatin; Creatinine; Cystatin C; Cytokines; Hepatitis A Virus Cellular Receptor 1; Humans; Inflammation; Iridoids; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Oxidative Stress; Poly(ADP-ribose) Polymerases; Tyrosine | 2017 |
Extracellular polysaccharides purified from Aureobasidium pullulans SM‑2001 (Polycan) inhibit dexamethasone‑induced muscle atrophy in mice.
Topics: Aldehydes; Animals; Antioxidants; Ascomycota; Body Weight; Catalase; Dexamethasone; Extracellular Space; Glutathione; Male; Malondialdehyde; Mice, Inbred ICR; Muscle Fibers, Skeletal; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Nitric Oxide Synthase Type II; Organ Size; Poly(ADP-ribose) Polymerases; Polysaccharides; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tyrosine | 2018 |
Thioredoxin-1 attenuates sepsis-induced cardiomyopathy after cecal ligation and puncture in mice.
Topics: Aldehydes; Animals; Apoptosis; Capillary Permeability; Cardiomyopathies; Carrier Proteins; Caspase 3; Disease Models, Animal; Echocardiography; Female; Heart; Heme Oxygenase-1; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Oxidative Stress; Repressor Proteins; Sepsis; Survivin; Thioredoxins; Tyrosine | 2017 |
Curcumin exerts a protective effect against premature ovarian failure in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anti-Mullerian Hormone; Apoptosis; Curcumin; Cyclin-Dependent Kinase Inhibitor p16; Deoxyguanosine; Disease Models, Animal; Female; Galactose; Gonads; Hypothalamo-Hypophyseal System; Mice, Inbred C57BL; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Protective Agents; RNA, Messenger; Tyrosine | 2018 |
Lead inhalation and hepatic damage: Morphological and functional evaluation in mice.
Topics: Administration, Inhalation; Air Pollutants; Aldehydes; Animals; Atmosphere Exposure Chambers; Biomarkers; Hepatic Insufficiency; Immunohistochemistry; Lead; Lead Poisoning; Leukocytes, Mononuclear; Liver; Male; Mice; Neutrophil Infiltration; Nitrosative Stress; Oxidative Stress; Random Allocation; Tissue Distribution; Toxicity Tests, Acute; Toxicity Tests, Chronic; Toxicokinetics; Tyrosine | 2018 |
Inhibition of GSK-3β on Behavioral Changes and Oxidative Stress in an Animal Model of Mania.
Topics: Aldehydes; Animals; Antioxidants; Behavior, Animal; Bipolar Disorder; Catalase; Dinoprost; Disease Models, Animal; Glutathione Peroxidase; Glycogen Synthase Kinase 3 beta; Lipid Peroxidation; Male; Motor Activity; Oxidative Stress; Protein Carbonylation; Rats, Wistar; Submitochondrial Particles; Superoxide Dismutase; Superoxides; Thiazoles; Tyrosine; Urea | 2019 |
Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis.
Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; CA1 Region, Hippocampal; Cytokines; Disease Models, Animal; Encephalitis; Humans; Lithium; Mice, Transgenic; Mutation; Plaque, Amyloid; Rats; Tyrosine | 2018 |
Metformin prevents murine ovarian aging.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Cellular Senescence; Estradiol; Estrous Cycle; Female; Hypoglycemic Agents; Metformin; Mice; Ovarian Reserve; Ovary; Oxidative Stress; Sirtuin 1; Tyrosine | 2019 |
Pathological changes induced by phosphine poisoning: a study on 8 children.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Aldehydes; Aluminum Compounds; Blood Chemical Analysis; Brain; Child; Child, Preschool; Female; Heart; Humans; Immunohistochemistry; Infant; Inhalation Exposure; Kidney; Liver; Lung; Male; Myocardium; Oxidative Stress; Phosphines; Statistics, Nonparametric; Tyrosine | 2020 |
Egg white consumption increases GSH and lowers oxidative damage in 110-week-old geriatric mice hearts.
Topics: Aging; Aldehydes; Amino Acids, Sulfur; Animal Feed; Animals; Antioxidants; Egg White; Glutathione; Glutathione Synthase; Inflammation; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Myocardium; Oxidative Stress; Tyrosine | 2020 |
Development of molecular and histological methods to evaluate stress oxidative biomarkers in sea bass (Dicentrarchus labrax).
Topics: Aldehydes; Animals; Aquaculture; Bass; Biomarkers; Central Nervous System; Fish Diseases; Gene Expression; Gills; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Immunohistochemistry; Immunoprecipitation; Kidney; Liver; Malondialdehyde; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Spleen; Stress, Physiological; Temperature; Tyrosine | 2020 |
TLR4, RAGE, and p-JNK/JNK mediated inflammatory aggression in osteoathritic human chondrocytes are counteracted by redox-sensitive phenolic olive compounds: Comparison with ibuprofen.
Topics: Aged; Aldehydes; Biomarkers; Cartilage, Articular; Cell Adhesion; Cell Survival; Chondrocytes; Female; Glycation End Products, Advanced; Humans; Ibuprofen; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipid Peroxides; Male; Middle Aged; Olea; Osteoarthritis; Oxidation-Reduction; Phenol; Phosphorylation; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Toll-Like Receptor 4; Tyrosine | 2020 |
Metformin inhibits the inflammatory and oxidative stress response induced by skin UVB-irradiation and provides 4-hydroxy-2-nonenal and nitrotyrosine formation and p53 protein activation.
Topics: Aldehydes; Animals; Carcinogenesis; DNA Damage; Female; Humans; Melanoma; Metformin; Mice; Oxidative Stress; Radiation Injuries, Experimental; Radiodermatitis; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Tyrosine; Ultraviolet Rays | 2020 |
The role of oxidative stress in the susceptibility of noise-impaired cochleae to synaptic loss induced by intracochlear electrical stimulation.
Topics: Action Potentials; Aldehydes; Animals; Antioxidants; Cochlea; Cochlear Implants; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Fatty Acids, Unsaturated; Guinea Pigs; Hair Cells, Auditory, Inner; Hearing Loss, Noise-Induced; Hydroxy Acids; Isoindoles; Organoselenium Compounds; Oxidative Stress; Severity of Illness Index; Synapses; Tyrosine | 2021 |