tyrosine has been researched along with 3-chloro-L-tyrosine in 80 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (11.25) | 18.2507 |
| 2000's | 39 (48.75) | 29.6817 |
| 2010's | 28 (35.00) | 24.3611 |
| 2020's | 4 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augustyn, E; Chien, HC; Colas, C; Finke, K; Giacomini, KM; Hansen, L; Heeren, N; Lin, L; Schlessinger, A; Thomas, AA; Zur, AA | 1 |
| Chen, QM; Geiger, JD; Glavin, GB; Gu, JG; LaBella, FS; McKenzie, JK; Smyth, DD | 1 |
| Kettle, AJ | 2 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Hsu, FF; Mueller, DM | 1 |
| Hazen, SL; Heinecke, JW | 1 |
| Halliwell, B | 1 |
| Crowley, JR; Hazen, SL; Heinecke, JW; Mueller, DM | 1 |
| Crow, JP | 1 |
| Baker, C; Evans, TW; Gutteridge, JM; Lamb, NJ; Quinlan, GJ | 1 |
| Davies, M; Dean, R; Fu, S; Wang, H | 1 |
| Chapman, AL; Kettle, AJ; Senthilmohan, R; Winterbourn, CC | 1 |
| Bruce Alexander, C; Crow, JP; De Andrade, JA; Jackson, RM; Matalon, S; McGiffin, DC; Randall Young, K; Viera, L; Zhu, S; Zorn, GL | 1 |
| Abu-Soud, HM; Hazen, SL; Podrez, EA | 1 |
| Cross, CE; Eiserich, JP; Marelich, GP; Nguyen, MN; Shigenaga, MK; Van Der Vliet, A | 1 |
| Anderson, MM; Brennan, ML; Crowley, JR; Hazen, SL; Heinecke, JW; Jacob, JS; Lim, LL; Lusis, AJ; Mehta, AC; Qu, XD; Shi, W; Shih, DM; Wang, X | 1 |
| Comhair, SA; Erzurum, SC; Hazen, SL; Kavuru, MS; Klein, DF; Lipscomb, MF; MacPherson, JC; Samoszuk, MK | 1 |
| Pizzo, SV; Wu, SM | 1 |
| Belaaouaj, A; Brennan, ML; Byun, J; Gaut, JP; Heinecke, JW; Henderson, JP; Hotchkiss, RS; Lusis, AJ; Richter, GM; Tran, HD; Yeh, GC | 1 |
| Heinecke, JW; Himmelfarb, J; Loseto, G; McMenamin, ME | 1 |
| Byun, J; Gaut, JP; Heinecke, JW; Tran, HD | 1 |
| Fujiwara, T; Hirao, I; Kigawa, T; Kodama, K; Mitsui, T; Nakayama, H; Nishikawa, K; Ohtsuki, T; Okuni, T; Takio, K; Yabuki, T; Yokogawa, T; Yokoyama, S | 1 |
| Belaaouaj, A; Byun, J; Carroll, JA; Gaut, JP; Heinecke, JW; Hotchkiss, RS; Lauber, WM; Tran, HD | 1 |
| Crowley, JR; Heinecke, JW; Rosen, H | 1 |
| Buss, IH; Darlow, BA; Kettle, AJ; Mogridge, N; Senthilmohan, R; Winterbourn, CC | 1 |
| Bergmann, R; Kopprasch, S; Pietzsch, J | 1 |
| Althaus, J; Ballard, PL; Ballard, RA; Banks, BA; Christie, J; Ischiropoulos, H; Lorch, SA; Merrill, JD; Schmidt, K | 1 |
| Fisher, MT; Khor, HK; Schöneich, C | 1 |
| Akiyama, K; Higashi, A; Higashi, N; Kawagishi, Y; Mita, H; Taniguchi, M | 1 |
| Bergt, C; Brunzell, J; Byun, J; Chait, A; Geary, RL; Green, PS; Heinecke, JW; Kassim, SY; McDonald, TO; O'brien, K; Oram, JF; Pennathur, S; Shao, B; Singh, P | 1 |
| Anantharamaiah, GM; Bergt, C; Brunzell, J; Byun, J; Chait, A; Fu, X; Geary, RL; Heinecke, JW; McDonald, TO; O'Brien, K; Oram, JF; Pennathur, S; Singh, P | 1 |
| Andersen, SO | 1 |
| Akiyama, K; Arimura, K; Higashi, A; Higashi, N; Mita, H; Ozawa, Y; Taniguchi, M; Tohma, S; Turikisawa, N | 1 |
| Becker, S; Brighton, LE; Carson, JL; Huang, YC; Li, Z; Soukup, JM | 1 |
| Fujioka, Y; Haginaka, J; Kunitomo, M; Morimoto, S; Yamaguchi, Y | 1 |
| Davis, RA | 1 |
| Choi, DK; Heinecke, JW; Jackson-Lewis, V; Pennathur, S; Perier, C; Przedborski, S; Teismann, P; Tieu, K; Vila, M; Vonsattel, JP; Wu, DC | 1 |
| Chai, H; Chen, C; Lin, PH; Lumsden, AB; Mohiuddin, I; Yao, Q | 1 |
| Haginaka, J; Kunitomo, M; Nakamura, K; Yamada, K; Yamaguchi, Y; Yoshikawa, N | 1 |
| Cameron, VA; Frampton, CM; Mocatta, TJ; Pilbrow, AP; Richards, AM; Senthilmohan, R; Winterbourn, CC | 1 |
| Chen, C; Lin, PH; Mu, H; Wang, X; Yao, Q | 1 |
| Chen, CM; Cheng, ML; Chiu, DT; Gu, PW; Ho, HY | 1 |
| Spencer, JP; Whiteman, M | 1 |
| Kang, JI; Neidigh, JW | 1 |
| Kagota, S; Kunitomo, M; Otsubo, K; Yamaguchi, Y | 1 |
| Gugliucci, A | 1 |
| Anzalone, R; Cappello, F; Colombo, M; Corrao, S; Di Gangi, C; Di Stefano, A; Eleuteri, E; Farina, F; Giannuzzi, P; La Rocca, G; Loria, T; Magno, F; Martorana, A; Patanè, F; Rinaldi, M; Sansone, F; Zummo, G | 1 |
| Haroune, N; Mouls, L; Pitt, AR; Silajdzic, E; Spickett, CM | 1 |
| Chen, CM; Cheng, ML; Chiu, DT; Gu, PW; Ho, HY; Li, JM; Wang, YL | 1 |
| Fu, X; Hazen, SL; Provencio, JJ; Ransohoff, RM; Rasmussen, PA; Siu, A | 1 |
| Blais, E; Kumarathasan, P; Saravanabhavan, G; Vincent, R | 1 |
| Andrié, RP; Baldus, S; Böger, RH; Didié, M; Ehmke, H; Eschenhagen, T; Freeman, BA; Friedrichs, K; Fu, X; Hazen, SL; Hirsch-Hoffmann, B; Klingel, K; Klinke, A; Lau, D; Lewalter, T; Meinertz, T; Nickenig, G; Reichenspurner, H; Rudolph, TK; Rudolph, V; Schrickel, JW; Schwoerer, AP; Seniuk, A; Sydow, K; Szoecs, K; Treede, H; von Leitner, EC; Wenzel, U; Willems, S; Zimmermann, WH | 1 |
| De Groote, D; Paquet, P; Piérard, GE | 1 |
| Balding, E; Berry, LJ; Brennan, S; Carlin, JB; Carzino, R; Chapman, AL; de Klerk, N; Douglas, T; Foo, C; Gangell, CL; Garratt, LW; Hall, GL; Harrison, J; Kettle, AJ; Kicic, A; Laing, IA; Logie, KM; Massie, J; Mott, LS; Murray, C; Parsons, F; Pillarisetti, N; Poreddy, SR; Ranganathan, SC; Robertson, CF; Robins-Browne, R; Robinson, PJ; Senthilmohan, R; Skoric, B; Sly, PD; Stick, SM; Sutanto, EN; Thomson, E; Williamson, E | 1 |
| Newbold, P; O'Donnell, C; Stockley, RA; Stone, H; Thong, B; White, P | 1 |
| Boggaram, V; Fu, J; Idell, S; Liu, MC; Liu, MY; Sakakibara, Y; Shetty, S; Suiko, M; Yasuda, S; Yasuda, T | 1 |
| Beubler, E; Fauler, G; Gauster, M; Heinemann, A; Holzer, M; Koefeler, H; Marsche, G; Pfeifer, T; Schuligoi, R; Stiegler, P; Wadsack, C | 1 |
| Curtis, MP; Hicks, AJ; Neidigh, JW | 1 |
| Bartosz, G; Robaszkiewicz, A; Soszynski, M | 1 |
| Heinecke, JW; Pennathur, S; Shao, B | 1 |
| Celermajer, DS; Davies, MJ; Harmer, JA; Pattison, DI; Talib, J | 1 |
| Delporte, C; Desmet, JM; Dufour, D; Franck, T; Madhoun, P; Moguilevsky, N; Nève, J; Nortier, J; Noyon, C; Raes, M; Rousseau, A; Serteyn, D; Van Antwerpen, P; Vanhaeverbeek, M; Vanhamme, L; Zouaoui Boudjeltia, K | 1 |
| Byun, J; Gillespie, BW; Heinecke, JW; Kaplan, MJ; Pennathur, S; Sands, RL; Saran, R; Slocum, JL; Tang, C; Vivekanandan-Giri, A | 1 |
| Jiang, S; Liu, X; Ren, H; Wang, L; Wang, X | 1 |
| Dedon, PC; Fox, JG; Kang, P; Knutson, CG; Korzenik, JR; Liberman, RG; Lu, K; Mangerich, A; Prestwich, EG; Raczynski, AR; Tannenbaum, SR; Wishnok, JS; Wogan, GN; Ye, W; Zeng, Y | 1 |
| Chowdhury, N; Delatorre, R; Frye, RE; James, SJ; Melnyk, S; Slattery, J; Taylor, H | 1 |
| Boxer, SG; Fried, SD; Wu, Y | 1 |
| Byun, J; de Andrade, JA; Kulkarni, T; Locy, ML; Pennathur, S; Thannickal, VJ; Vivekanandan-Giri, A; Zeng, L; Zhi, D | 1 |
| Barosova, H; Belacek, J; Fenclova, Z; Kacer, P; Komarc, M; Kukutschova, J; Navratil, T; Pelcl, T; Pelclova, D; Schwarz, J; Syslova, K; Turci, F; Vlckova, S; Zakharov, S; Zdimal, V; Zikova, N | 1 |
| Blake, TA; Crow, BS; Garton, JW; Johnson, RC; Pantazides, BG; Perez, JW; Quiñones-González, J; Thomas, JD; Winkeljohn, WR | 1 |
| Cheng, D; Maghzal, GJ; Stocker, R; Talib, J | 1 |
| Afshinnia, F; Byun, J; Gadegbeku, CA; Kretzler, M; Magnone, MC; Pennathur, S; Valastro, B; Whatling, C; Zeng, L | 1 |
| Atkins, KB; Brosius, FC; Byun, J; Mathew, AV; Pennathur, S; Zeng, L | 1 |
| Boxer, SG; Weaver, JB | 1 |
| Choe, JK; Komaki, Y; Mitch, WA; Plewa, MJ; Simpson, AM | 1 |
| Date, M; Haruna, KI; Iraha, F; Mukai, T; Ohtake, K; Sakamoto, K; Takahashi, M; Yokoyama, K | 1 |
| Arai, T; Hoshi, T; Nishio, T; Nogami, M; Toukairin, Y | 2 |
| Fleszar, MG; Fortuna, P; Kosyk, B; Krzystek-Korpacka, M; Zawadzki, M | 1 |
| Bhat, RV; Chua, J; Fritsche-Danielson, R; Gan, LM; Hausenloy, DJ; Hernandez-Resendiz, S; Jonsson, MKB; Knöll, R; Kp, MMJ; Liehn, EA; Lin, YH; Michaëlsson, E; Ramachandra, CJA; Ryden-Markinhuhta, K; Sadayappan, S; Shim, W; Tang, HC; Wong, P | 1 |
3 review(s) available for tyrosine and 3-chloro-L-tyrosine
| Article | Year |
|---|---|
Measurement and significance of free and protein-bound 3-nitrotyrosine, 3-chlorotyrosine, and free 3-nitro-4-hydroxyphenylacetic acid in biologic samples: a high-performance liquid chromatography method using electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Nitrophenols; Phenylacetates; Protein Binding; Proteins; Tyrosine | 1999 |
Myeloperoxidase-generated oxidants and atherosclerosis.
Topics: Aldehydes; Amino Acids; Animals; Arteriosclerosis; Catalysis; Free Radicals; Humans; Lipoproteins, LDL; Nitro Compounds; Oxidants; Oxidation-Reduction; Peroxidase; Tyrosine | 2000 |
Nitrotyrosine and chlorotyrosine: clinical significance and biological functions in the vascular system.
Topics: Animals; Atherosclerosis; Endothelium, Vascular; Humans; Oxidative Stress; Tyrosine; Vasculitis | 2006 |
1 trial(s) available for tyrosine and 3-chloro-L-tyrosine
| Article | Year |
|---|---|
Plasma 3-nitrotyrosine and outcome in neonates with severe bronchopulmonary dysplasia after inhaled nitric oxide.
Topics: Administration, Inhalation; Birth Weight; Bronchopulmonary Dysplasia; Chromatography, High Pressure Liquid; Female; Gestational Age; Humans; Infant; Infant, Newborn; Logistic Models; Male; Mass Spectrometry; Nitric Oxide; Risk Factors; Time Factors; Treatment Outcome; Tyrosine; Ventilators, Mechanical | 2003 |
76 other study(ies) available for tyrosine and 3-chloro-L-tyrosine
| Article | Year |
|---|---|
LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs.
Topics: Dose-Response Relationship, Drug; Humans; Large Neutral Amino Acid-Transporter 1; Models, Molecular; Molecular Structure; Phenylalanine; Structure-Activity Relationship; Tyrosine | 2016 |
Chlorotyrosine exerts renal effects and antagonizes renal and gastric responses to atrial natriuretic peptide.
Topics: Animals; Atrial Natriuretic Factor; Cerebral Ventricles; Diuresis; Enzyme Activation; Gastric Acid; Gastric Mucosa; Guanylate Cyclase; Kidney; Male; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrosine 3-Monooxygenase | 1994 |
Neutrophils convert tyrosyl residues in albumin to chlorotyrosine.
Topics: Amino Acid Sequence; Humans; Hypochlorous Acid; In Vitro Techniques; Inflammation; Molecular Sequence Data; Neutrophils; Oligopeptides; Peroxidase; Serum Albumin; Tyrosine | 1996 |
Human neutrophils employ chlorine gas as an oxidant during phagocytosis.
Topics: Chlorine; Gas Chromatography-Mass Spectrometry; Humans; Inflammation; Leukocytes; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytosis; Phagosomes; Tyrosine | 1996 |
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
Topics: Aorta; Apolipoproteins B; Arteriosclerosis; Biomarkers; Chlorine; Humans; Hypochlorous Acid; Lipoproteins; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 1997 |
What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
Topics: Biomarkers; Free Radicals; Humans; Molecular Structure; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrous Acid; Peroxidase; Superoxides; Tyrosine | 1997 |
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation.
Topics: Analysis of Variance; Aorta; Arteriosclerosis; Biomarkers; Calibration; Carbon; Carbon Isotopes; Catalysis; Chlorine; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypochlorous Acid; Inflammation; Lipoproteins, LDL; Male; Peroxidase; Sensitivity and Specificity; Tyrosine | 1997 |
Detection of 3-chlorotyrosine in proteins exposed to neutrophil oxidants.
Topics: Blood Proteins; Chlorides; Chromatography, High Pressure Liquid; Electrochemistry; Fluorescence; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Oxidants; Peroxidase; Tyrosine | 1999 |
Oxidative damage to proteins of bronchoalveolar lavage fluid in patients with acute respiratory distress syndrome: evidence for neutrophil-mediated hydroxylation, nitration, and chlorination.
Topics: Adolescent; Adult; Aged; Biomarkers; Bronchoalveolar Lavage Fluid; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyl Radical; Hydroxylation; Hypochlorous Acid; Linear Models; Male; Middle Aged; Neutrophil Activation; Neutrophils; Nitrates; Oxidants; Oxidative Stress; Proteins; Respiration, Artificial; Respiratory Distress Syndrome; Statistics, Nonparametric; Tyrosine | 1999 |
Reactions of hypochlorous acid with tyrosine and peptidyl-tyrosyl residues give dichlorinated and aldehydic products in addition to 3-chlorotyrosine.
Topics: Animals; Humans; Hypochlorous Acid; Lipoproteins, LDL; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Serum Albumin, Bovine; Tyrosine | 2000 |
Comparison of mono- and dichlorinated tyrosines with carbonyls for detection of hypochlorous acid modified proteins.
Topics: Animals; Antibodies; Antibody Specificity; Bromates; Carbonic Acid; Cattle; Chlorine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitopes; Hypochlorous Acid; Inflammation; Mass Spectrometry; Oxidants; Oxidative Stress; Serum Albumin; Tyrosine | 2000 |
Protein nitration, metabolites of reactive nitrogen species, and inflammation in lung allografts.
Topics: Adult; Bronchiolitis Obliterans; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Female; Forced Expiratory Volume; Graft Rejection; Humans; Lung; Lung Transplantation; Male; Nitrates; Nitrites; Postoperative Complications; Prognosis; Tyrosine | 2000 |
Myeloperoxidase and protein oxidation in cystic fibrosis.
Topics: Adult; Bronchi; Case-Control Studies; Cell Line; Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Synergism; Humans; Hydrogen Peroxide; Nitrates; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Peroxidases; Proteins; Respiratory System; Sputum; Trachea; Tyrosine | 2000 |
Increased atherosclerosis in myeloperoxidase-deficient mice.
Topics: Animals; Arteriosclerosis; Candida albicans; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 2001 |
Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.
Topics: Eosinophil Peroxidase; Eosinophils; Free Radicals; Humans; Immunohistochemistry; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Oxidants; Oxidation-Reduction; Peroxidases; Phenylpropionates; Proteins; Reactive Oxygen Species; Status Asthmaticus; Tyrosine | 2001 |
alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation.
Topics: alpha-Macroglobulins; Arthritis, Rheumatoid; Humans; Hypochlorous Acid; Mass Spectrometry; Osteoarthritis; Oxidation-Reduction; Peptide Hydrolases; Synovial Fluid; Tyrosine | 2001 |
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.
Topics: Animals; Bromine; Chlorine; Disease Models, Animal; HL-60 Cells; Humans; Hypochlorous Acid; Ions; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxidants; Peroxidase; Sepsis; Tyrosine | 2001 |
Myeloperoxidase-catalyzed 3-chlorotyrosine formation in dialysis patients.
Topics: Adult; Aged; Blood Proteins; Female; Gas Chromatography-Mass Spectrometry; Humans; Leukocytes; Male; Middle Aged; Oxidative Stress; Peroxidase; Phagocytes; Renal Dialysis; Renal Insufficiency; Tyrosine | 2001 |
Artifact-free quantification of free 3-chlorotyrosine, 3-bromotyrosine, and 3-nitrotyrosine in human plasma by electron capture-negative chemical ionization gas chromatography mass spectrometry and liquid chromatography-electrospray ionization tandem mass
Topics: Artifacts; Gas Chromatography-Mass Spectrometry; Humans; Male; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2002 |
An unnatural base pair for incorporating amino acid analogs into proteins.
Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Cell-Free System; Codon; DNA; DNA-Directed RNA Polymerases; Escherichia coli; Gas Chromatography-Mass Spectrometry; Genetic Variation; Models, Chemical; Molecular Sequence Data; Plasmids; Protein Biosynthesis; Protein Engineering; RNA, Messenger; RNA, Transfer; Time Factors; Transcription, Genetic; Tyrosine; Viral Proteins | 2002 |
Myeloperoxidase produces nitrating oxidants in vivo.
Topics: Animals; Klebsiella Infections; Klebsiella pneumoniae; Mice; Peritonitis; Peroxidase; Reactive Nitrogen Species; Tyrosine | 2002 |
Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis.
Topics: Bacterial Proteins; Chlorides; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Nitrites; Peroxidase; Phagocytosis; Tyrosine | 2002 |
3-Chlorotyrosine as a marker of protein damage by myeloperoxidase in tracheal aspirates from preterm infants: association with adverse respiratory outcome.
Topics: Biomarkers; Chronic Disease; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Neutrophils; Oxidative Stress; Peroxidase; Respiratory Distress Syndrome, Newborn; Trachea; Tyrosine; Ureaplasma Infections; Ureaplasma urealyticum | 2003 |
Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: the use of N(O,S)-ethoxycarbonyltrifluoroethyl ester derivatives and gas chromatography/mass spectrometry.
Topics: Calibration; Esters; Gas Chromatography-Mass Spectrometry; Humans; Lipoproteins, LDL; Oxidation-Reduction; Proteins; Tyrosine | 2003 |
Potential role of methionine sulfoxide in the inactivation of the chaperone GroEL by hypochlorous acid (HOCl) and peroxynitrite (ONOO-).
Topics: Amino Acid Sequence; Arteriosclerosis; Chaperonin 60; Chromatography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolysis; Hypochlorous Acid; Mass Spectrometry; Methionine; Methionine Sulfoxide Reductases; Molecular Chaperones; Molecular Sequence Data; Oxidants; Oxidoreductases; Oxygen; Peptides; Peroxynitrous Acid; Phagocytes; Protein Binding; Time Factors; Trypsin; Tyrosine | 2004 |
Urinary 3-bromotyrosine and 3-chlorotyrosine concentrations in asthmatic patients: lack of increase in 3-bromotyrosine concentration in urine and plasma proteins in aspirin-induced asthma after intravenous aspirin challenge.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Case-Control Studies; Eosinophils; Gas Chromatography-Mass Spectrometry; Humans; Leukocyte Count; Leukotriene E4; Neutrophils; Tyrosine | 2004 |
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
Topics: Arteries; Arteriosclerosis; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Epitopes; Gas Chromatography-Mass Spectrometry; Humans; Immunohistochemistry; Inflammation; Lipid Peroxides; Lipoproteins, HDL; Mass Spectrometry; Nitric Oxide; Nitrogen; Oxygen; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Taurine; Time Factors; Tunica Intima; Tyrosine | 2004 |
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Arteries; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Chromatography, Liquid; Humans; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Peroxidase; Tyrosine | 2004 |
Chlorinated tyrosine derivatives in insect cuticle.
Topics: Animals; Cockroaches; Grasshoppers; Insecta; Moths; Rhodnius; Species Specificity; Tenebrio; Tissue Distribution; Tyrosine | 2004 |
Urinary eicosanoid and tyrosine derivative concentrations in patients with vasculitides.
Topics: Adult; Aged; Churg-Strauss Syndrome; Eicosanoids; Eosinophil-Derived Neurotoxin; Female; Humans; Leukotriene E4; Male; Middle Aged; Tyrosine; Vasculitis | 2004 |
3-nitrotyrosine attenuates respiratory syncytial virus infection in human bronchial epithelial cell line.
Topics: Antiviral Agents; Bronchi; Cell Line; Chemokine CCL5; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Interferon Regulatory Factor-3; Interferon-gamma; Interleukin-8; Microtubules; Nitrogen; Nitrogen Dioxide; Respiratory Mucosa; Respiratory Syncytial Virus Infections; Signal Transduction; Transcription Factors; Tubulin; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Facilitated nitration and oxidation of LDL in cigarette smokers.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Female; Guanine; Humans; Lipoproteins, LDL; Male; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Smoking; Thiobarbituric Acid Reactive Substances; Tyrosine; Vitamin E | 2005 |
Isolation and structure elucidation of the new fungal metabolite (-)-xylariamide A.
Topics: Animals; Artemia; Ascomycota; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Tyrosine | 2005 |
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Animals; Brain; Corpus Striatum; Dopamine; Drug Evaluation, Preclinical; Enzyme Induction; Humans; Huntington Disease; Hypochlorous Acid; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2005 |
Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Deoxyguanosine; Disease Models, Animal; Fatty Acids, Nonesterified; Hypertension; Inflammation; Insulin; Male; Metabolic Syndrome; Molecular Structure; Musa; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Inbred SHR; Thiobarbituric Acid Reactive Substances; Triglycerides; Triterpenes; Tyrosine | 2006 |
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Neurotransmitter Agents; New Zealand; Peroxidase; Prognosis; Proportional Hazards Models; Protein Carbonylation; Radionuclide Imaging; Retrospective Studies; Sex Factors; Stroke Volume; Tyrosine; Ventricular Dysfunction, Left | 2007 |
Chlorotyrosine promotes human aortic smooth muscle cell migration through increasing superoxide anion production and ERK1/2 activation.
Topics: Aorta; Becaplermin; Cell Culture Techniques; Cell Movement; Extracellular Signal-Regulated MAP Kinases; Humans; Integrins; Matrix Metalloproteinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Superoxides; Tyrosine | 2008 |
Elevated levels of myeloperoxidase, white blood cell count and 3-chlorotyrosine in Taiwanese patients with acute myocardial infarction.
Topics: Acute Disease; Aged; Biomarkers; Female; Humans; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Peroxidase; Sensitivity and Specificity; Taiwan; Tyrosine | 2008 |
Loss of 3-chlorotyrosine by inflammatory oxidants: implications for the use of 3-chlorotyrosine as a bio-marker in vivo.
Topics: Animals; Biomarkers; HL-60 Cells; Humans; Hypochlorous Acid; Inflammation; Macrophage Activation; Macrophages; Mice; Neutrophils; Nitrites; Oxidants; Peroxidase; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine | 2008 |
Hypochlorous acid damages histone proteins forming 3-chlorotyrosine and 3,5-dichlorotyrosine.
Topics: Amino Acid Sequence; Chlorine; Histones; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Tyrosine | 2008 |
Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Glucose; Body Weight; Deoxyguanosine; Disease Models, Animal; Inflammation; Insulin; Lipids; Lipoproteins, LDL; Metabolic Syndrome; Oxidative Stress; Peroxidase; Rats; Rats, Inbred SHR; Tyrosine; Ubiquinone | 2008 |
Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes.
Topics: Aryldialkylphosphatase; Cysteine; Granulocytes; Humans; Hypochlorous Acid; Lipoproteins, HDL; Plasminogen; Streptokinase; Tyrosine | 2008 |
Oxidative stress induces myeloperoxidase expression in endocardial endothelial cells from patients with chronic heart failure.
Topics: Cells, Cultured; Chronic Disease; Endothelial Cells; Gene Expression; Heart Failure; Humans; Hydrogen Peroxide; Immunohistochemistry; Myocardium; Oxidants; Oxidative Stress; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine; Umbilical Veins | 2009 |
Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins.
Topics: 5-Hydroxytryptophan; Amino Acid Sequence; Animals; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Muramidase; Oxidation-Reduction; Peptides; Protein Processing, Post-Translational; Proteins; Sequence Analysis, Protein; Tyrosine | 2009 |
Oxidative damage markers and antioxidants in patients with acute myocardial infarction and their clinical significance.
Topics: Antioxidants; Humans; Inflammation; Myocardial Infarction; Oxidative Stress; Peroxidase; Tyrosine | 2008 |
CSF neutrophils are implicated in the development of vasospasm in subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Neutrophils; Reactive Oxygen Species; Subarachnoid Hemorrhage; Tandem Mass Spectrometry; Tyrosine; Vasospasm, Intracranial | 2010 |
A high performance liquid chromatography-electrochemical array method for the measurement of oxidative/nitrative changes in human urine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Biomarkers; Chromatography, High Pressure Liquid; Deoxyguanosine; Electrochemical Techniques; Female; Humans; Hydrogen-Ion Concentration; Linear Models; Male; Oxidative Stress; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tyrosine | 2010 |
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Heart Atria; Humans; Lymphocyte Activation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neutrophils; Peroxidase; Tyrosine | 2010 |
Functionally active macrophage-derived myeloperoxidase in the skin of drug-induced toxic epidermal necrolysis.
Topics: Adolescent; Adult; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blister; Female; Humans; Hypochlorous Acid; Keratinocytes; Lewis X Antigen; Macrophages; Male; Middle Aged; Peroxidase; Stevens-Johnson Syndrome; Tyrosine | 2010 |
Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.
Topics: Bronchoalveolar Lavage Fluid; Child; Child, Preschool; Cystic Fibrosis; Disease Progression; Female; Humans; Infant; Inflammation; Male; Neutrophils; Oxidation-Reduction; Peroxidase; Pseudomonas aeruginosa; Respiratory Tract Infections; Tyrosine | 2010 |
3-Chlorotyrosine in sputum of COPD patients: relationship with airway inflammation.
Topics: Aged; Biomarkers; Cell Survival; Female; Humans; Male; Mass Spectrometry; Middle Aged; Neutrophils; Peroxidase; Pulmonary Disease, Chronic Obstructive; Sputum; Tyrosine | 2010 |
Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: role of the human SULT1A3.
Topics: Arylsulfotransferase; Cell Line; Endothelial Cells; Humans; Inflammation Mediators; Lung; Respiratory Mucosa; Sulfates; Sulfotransferases; Tyrosine | 2011 |
Protein carbamylation renders high-density lipoprotein dysfunctional.
Topics: Adult; Aged; Apolipoprotein A-I; Atherosclerosis; CD36 Antigens; Cells, Cultured; Cholesterol; Cyanates; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Mass Spectrometry; Middle Aged; Oxidation-Reduction; Peroxidase; Protein Processing, Post-Translational; Tyrosine | 2011 |
Kinetics of 3-chlorotyrosine formation and loss due to hypochlorous acid and chloramines.
Topics: Biomarkers; Chloramines; Chlorides; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Kinetics; Spectrophotometry, Ultraviolet; Tyrosine | 2011 |
Detection of 3-chlorinated tyrosine residues in human cells by flow cytometry.
Topics: Cell Line; Cell Survival; Flow Cytometry; Humans; Tyrosine | 2011 |
Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions.
Topics: Apolipoprotein A-I; Atherosclerosis; Halogenation; Humans; Hypochlorous Acid; Lipoproteins, HDL; Nitrogen; Oxidation-Reduction; Oxidative Stress; Peroxidase; Protein Processing, Post-Translational; Tyrosine | 2012 |
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine.
Topics: Biomarkers; Blood Proteins; Case-Control Studies; Female; Humans; Male; Oxidants; Oxidation-Reduction; Peroxidase; Smoking; Sulfhydryl Compounds; Thiocyanates; Tyrosine | 2012 |
Simultaneous measurement of protein-bound 3-chlorotyrosine and homocitrulline by LC-MS/MS after hydrolysis assisted by microwave: application to the study of myeloperoxidase activity during hemodialysis.
Topics: Aged; Aged, 80 and over; Animals; Blood Chemical Analysis; Blood Proteins; Chromatography, Liquid; Citrulline; Female; Humans; Hydrolysis; Lysine; Male; Microwaves; Middle Aged; Peroxidase; Renal Dialysis; Tandem Mass Spectrometry; Time Factors; Tyrosine | 2012 |
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.
Topics: Adult; Aged; Apolipoprotein A-I; Arthritis, Rheumatoid; Cardiovascular Diseases; Case-Control Studies; Cholesterol; Female; Halogenation; Humans; Lipoproteins, HDL; Male; Middle Aged; Oxidation-Reduction; Peptide Mapping; Peroxidase; Tandem Mass Spectrometry; Tyrosine | 2013 |
Measurement of acid dissociation constants and ionic mobilities of 3-nitro-tyrosine and 3-chloro-tyrosine by capillary zone electrophoresis.
Topics: Acids; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Ionic Liquids; Ions; Static Electricity; Tyrosine | 2013 |
Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease.
Topics: Acute-Phase Proteins; Animals; Biomarkers; Chemokines; Cytokines; Deoxycytidine; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Female; Helicobacter hepaticus; Helicobacter Infections; Humans; Immunity, Innate; Inflammatory Bowel Diseases; Male; Mice; Mice, Knockout; Tyrosine | 2013 |
Redox metabolism abnormalities in autistic children associated with mitochondrial disease.
Topics: Age Factors; Biomarkers; Child; Child Development Disorders, Pervasive; Female; Glutathione; Humans; Language Development; Male; Mitochondrial Diseases; Neuropsychological Tests; Oxidation-Reduction; Oxidative Stress; Tyrosine | 2013 |
Dissecting Proton Delocalization in an Enzyme's Hydrogen Bond Network with Unnatural Amino Acids.
Topics: Amino Acid Substitution; Crystallography, X-Ray; Hydrogen Bonding; Kinetics; Models, Molecular; Protein Conformation; Protons; Pseudomonas putida; Steroid Isomerases; Thermodynamics; Tyrosine | 2015 |
Oxidative Modifications of Protein Tyrosyl Residues Are Increased in Plasma of Human Subjects with Interstitial Lung Disease.
Topics: Animals; Biomarkers; Cells, Cultured; Female; Humans; Lung Diseases, Interstitial; Male; Mice; Mice, Inbred C57BL; Middle Aged; Oxidative Stress; Tandem Mass Spectrometry; Tyrosine | 2016 |
Oxidative stress markers are elevated in exhaled breath condensate of workers exposed to nanoparticles during iron oxide pigment production.
Topics: Adult; Aldehydes; Biomarkers; Breath Tests; Dinoprost; Ferric Compounds; Guanosine; Humans; Male; Malondialdehyde; Middle Aged; Nanoparticles; Oxidative Stress; Tandem Mass Spectrometry; Tyrosine | 2016 |
Simultaneous Measurement of 3-Chlorotyrosine and 3,5-Dichlorotyrosine in Whole Blood, Serum and Plasma by Isotope Dilution HPLC-MS-MS.
Topics: Biomarkers; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Inflammation; Limit of Detection; Plasma; Quality Control; Radioisotope Dilution Technique; Reproducibility of Results; Retrospective Studies; Solid Phase Extraction; Tandem Mass Spectrometry; Tyrosine | 2016 |
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
Topics: Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Halogenation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Mice; Oxidation-Reduction; Peroxidase; Phenanthridines; Tandem Mass Spectrometry; Tyrosine; Vascular Diseases | 2016 |
Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Oxidative Stress; Peroxidase; Renal Insufficiency, Chronic; Risk Factors; Severity of Illness Index; Tyrosine; Young Adult | 2017 |
Myeloperoxidase-derived oxidants damage artery wall proteins in an animal model of chronic kidney disease-accelerated atherosclerosis.
Topics: Animals; Aorta; Atherosclerosis; Blood Urea Nitrogen; Creatinine; Diet, Fat-Restricted; Diet, High-Fat; Dietary Fats; Disease Models, Animal; Disease Progression; Kidney Failure, Chronic; Kidney Function Tests; Lipids; Lipoproteins; Macrophages; Male; Mice; Mice, Knockout; Muscle Proteins; Nephrectomy; Oxidants; Oxidative Stress; Parathyroid Hormone; Peroxidase; Receptors, LDL; Tyrosine; Vasodilation | 2018 |
Genetic Code Expansion in Rhodobacter sphaeroides to Incorporate Noncanonical Amino Acids into Photosynthetic Reaction Centers.
Topics: Amino Acids; Codon, Terminator; Microorganisms, Genetically-Modified; Monoiodotyrosine; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Plasmids; Protein Biosynthesis; Rhodobacter sphaeroides; Tyrosine | 2018 |
Chlorotyrosines versus Volatile Byproducts from Chlorine Disinfection during Washing of Spinach and Lettuce.
Topics: Animals; Chlorine; CHO Cells; Cricetinae; Cricetulus; Disinfectants; Disinfection; Halogenation; Lactuca; Spinacia oleracea; Tyrosine; Water Pollutants, Chemical; Water Purification | 2018 |
Engineering an Automaturing Transglutaminase with Enhanced Thermostability by Genetic Code Expansion with Two Codon Reassignments.
Topics: Amino Acid Substitution; Bacterial Proteins; Escherichia coli; Genetic Code; Genetic Engineering; Half-Life; Lysine; Protein Stability; Recombinant Proteins; Streptomyces; Temperature; Transglutaminases; Tyrosine | 2018 |
Determination of 3-chloro-l-tyrosine as a novel indicator of chlorine poisoning utilizing gas chromatography-mass spectrometric analysis.
Topics: Autopsy; Biomarkers; Chlorine; Depressive Disorder; Forensic Sciences; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Poisoning; Pulmonary Edema; Suicide; Tyrosine | 2020 |
Simultaneous LC-MS/MS-Based Quantification of Free 3-Nitro-l-tyrosine, 3-Chloro-l-tyrosine, and 3-Bromo-l-tyrosine in Plasma of Colorectal Cancer Patients during Early Postoperative Period.
Topics: Aged; Biomarkers; Chromatography, Liquid; Colorectal Neoplasms; Female; Humans; Inflammation; Male; Metabolomics; Middle Aged; Nitrosative Stress; Oxidative Stress; Postoperative Complications; Postoperative Period; Prospective Studies; Reactive Oxygen Species; Reproducibility of Results; Sensitivity and Specificity; Surgical Wound Infection; Tandem Mass Spectrometry; Tyrosine | 2020 |
Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes.
Topics: Animals; Cardiac Myosins; Cardiomyopathy, Hypertrophic; Carrier Proteins; Cell Line; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertrophy, Left Ventricular; Induced Pluripotent Stem Cells; Male; Mice, Inbred C57BL; Mutation, Missense; Myocardial Contraction; Myocytes, Cardiac; Myosin Heavy Chains; Peroxidase; Phosphorylation; Reactive Oxygen Species; Tyrosine; Ventricular Function, Left | 2022 |
Development of an LC-MS/MS method for quantification of 3-chloro-L-tyrosine as a candidate marker of chlorine poisoning.
Topics: Chlorine; Chromatography, Liquid; Humans; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tyrosine | 2021 |