tyrosine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; alpha-Methyltyrosine; Animals; Dopamine; Methyltyrosines; Mice; Mice, Inbred Strains; Nerve Endings; Neurons; Oxidation-Reduction; Reserpine; Synaptosomes; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Injections, Intravenous; Levodopa; Male; Mice; Mice, Inbred C57BL; Parkinson Disease, Secondary; Receptors, Dopamine; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 5-Hydroxytryptophan; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Pyridines; Rats; Rats, Inbred Strains; Species Specificity; Time Factors; Tryptophan; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Male; Nomifensine; Nucleus Accumbens; Pyridines; Rats; Rats, Inbred Strains; Sulpiride; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Depression, Chemical; Hydroxylation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Pyridines; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Male; Monoamine Oxidase; Pargyline; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Oxidoreductases; Animals; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Male; Mice; Mice, Inbred Strains; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide Synthase; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Central Nervous System Stimulants; Corpus Striatum; Fluorine Radioisotopes; Macaca; Parkinson Disease, Secondary; Reference Values; Tomography, Emission-Computed; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Disease Progression; Dopamine Agents; Fluorine Radioisotopes; Macaca mulatta; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Neurotoxins; Pargyline; Parkinson Disease, Secondary; Tomography, Emission-Computed; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Dopamine Agents; Enzyme Activation; Female; Glial Fibrillary Acidic Protein; Gliosis; Mice; Mice, Inbred C57BL; Neurotoxins; Phosphorylation; RNA, Messenger; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Macaca mulatta; Parkinson Disease, Secondary; Tomography, Emission-Computed; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Dopamine Agents; Enzyme Inhibitors; Immunohistochemistry; Indazoles; Male; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Papio; Substantia Nigra; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acids; Animals; Brain; Chelating Agents; Dopamine Agents; Free Radicals; Gas Chromatography-Mass Spectrometry; Male; Mice; Mice, Inbred C57BL; Nitrates; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Pentetic Acid; Tissue Distribution; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catechols; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Female; Free Radicals; Glutathione; Glutathione Peroxidase; Heterozygote; Homovanillic Acid; Homozygote; Huntington Disease; Male; Malonates; Mice; Mice, Inbred Strains; Mice, Knockout; MPTP Poisoning; Nitro Compounds; Oxidative Stress; Parkinson Disease, Secondary; Propionates; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Catheterization; Caudate Nucleus; Cell Line; Dependovirus; Dopamine; Drug Administration Routes; Drug Combinations; Fluorine Radioisotopes; Genetic Therapy; Genetic Vectors; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Neurons; Parkinson Disease, Secondary; Prodrugs; Putamen; Tomography, Emission-Computed; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; beta-Synuclein; Cell Line; Corpus Striatum; Disease Models, Animal; Humans; Kidney; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Oxidation-Reduction; Parkinsonian Disorders; Peroxynitrous Acid; Precipitin Tests; Protein Processing, Post-Translational; Synaptophysin; Synucleins; Transfection; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Glycolysis; Hydroxylation; Lactic Acid; Male; Manganese; Manganese Poisoning; MPTP Poisoning; Neostriatum; Neurotoxins; Rats; Rats, Wistar; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Bacterial Agents; Astrocytes; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Interleukin-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Minocycline; NADPH Oxidases; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Substantia Nigra; Tyrosine; Tyrosine 3-Monooxygenase; Up-Regulation

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Carotid Arteries; Corpus Striatum; Disease Models, Animal; Dopamine; Female; Fluorine Radioisotopes; Histocytochemistry; Humans; Injections, Intra-Arterial; Macaca mulatta; Male; Neurochemistry; Parkinson Disease, Secondary; Parkinsonian Disorders; Tomography, Emission-Computed; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Active Transport, Cell Nucleus; Animals; Antigens, CD; Astrocytes; Chromatography, High Pressure Liquid; Cytokine Receptor gp130; Dimerization; DNA-Binding Proteins; DNA, Complementary; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Immunoblotting; Immunohistochemistry; Interleukin-6; Janus Kinase 2; Leukemia Inhibitory Factor; Ligands; Male; MAP Kinase Signaling System; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Nomifensine; Oncostatin M; Peptides; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Time Factors; Tissue Distribution; Trans-Activators; Tyrosine; Up-Regulation

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animal Feed; Animals; Antioxidants; Astrocytes; Blotting, Western; Body Weight; Chromatography, High Pressure Liquid; Dietary Fats; Disease Susceptibility; Dopamine; Dopamine Agents; Glial Fibrillary Acidic Protein; Immunoblotting; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; MPTP Poisoning; Neurons; Neurotoxicity Syndromes; Nitrates; Nitric Oxide; Nitrites; Obesity; Oxidative Stress; Phosphorylation; Substantia Nigra; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Cholesterol; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Microglia; Neostriatum; Nitrates; Nitric Oxide; Oxidants; Simvastatin; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amyotrophic Lateral Sclerosis; Animals; Brain; Corpus Striatum; Dopamine; Drug Evaluation, Preclinical; Enzyme Induction; Humans; Huntington Disease; Hypochlorous Acid; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzoquinones; Blotting, Western; Brain; Cell Death; Cell Nucleus; Cytosol; Disease Models, Animal; DNA-Binding Proteins; Dopamine; Dopamine Agents; Enzyme Inhibitors; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Immunohistochemistry; Lactams, Macrocyclic; Male; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Chaperones; Neoplasm Proteins; Neurons; Neurotoxins; Parkinson Disease; Quinones; Time Factors; Transcription Factors; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biomarkers; Cell Count; Estradiol; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine; Up-Regulation

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3-Iodobenzylguanidine; Animals; Dopamine; Mice; Myocardium; Neostriatum; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Parkinson Disease; Time Factors; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Flurbiprofen; Humans; Inflammation; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Motor Activity; MPTP Poisoning; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidoreductases; Parkinson Disease; Rotarod Performance Test; Substantia Nigra; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Astrocytes; Cell Death; Coculture Techniques; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hindlimb; Inflammation; Male; Mice; Mice, Transgenic; Motor Activity; Neurons; Neurotoxins; NF-kappaB-Inducing Kinase; Nitric Oxide Synthase Type II; Protein Serine-Threonine Kinases; Substantia Nigra; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Aniline Compounds; Animals; Brain; Calcium-Binding Proteins; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Gene Expression Regulation; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Motor Activity; MPTP Poisoning; Neuroprotective Agents; Phenyl Ethers; Phosphorylation; Rotarod Performance Test; Sodium-Calcium Exchanger; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Apoptosis; Boron Compounds; Calcium; Calpain; Caspase 3; Caspase 9; Cell Line, Tumor; DNA, Mitochondrial; Dopamine Agents; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation; Humans; Hydro-Lyases; Mice; Mitochondria; Neuroblastoma; Peroxiredoxins; Reactive Oxygen Species; RNA, Small Interfering; Subcellular Fractions; Transfection; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cell Line; Cells, Cultured; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroimmunomodulation; Neuroprotective Agents; NF-kappa B; Phosphorylation; Rats, Sprague-Dawley; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antigens, CD; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Fumarates; Gene Expression Regulation; Humans; Maleates; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; NF-E2-Related Factor 2; Parkinsonian Disorders; Rats; Signal Transduction; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Cell Line; Disease Models, Animal; Humans; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease, Secondary; Tyrosine

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Astrocytes; Behavior, Animal; Cyclooxygenase 2; Cytokines; Disease Models, Animal; DNA Damage; Dopamine Plasma Membrane Transport Proteins; Inflammation; Mice, Inbred C57BL; Microglia; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Nitrosative Stress; Oxazoles; Oxidative Stress; Parkinson Disease; Poly Adenosine Diphosphate Ribose; Transcription Factor RelA; Tyrosine; Tyrosine 3-Monooxygenase

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Disease Models, Animal; Flavones; Gait; Mice; Mice, Inbred C57BL; Parkinson Disease; Parkinsonian Disorders; Substantia Nigra; Tyrosine; Tyrosine 3-Monooxygenase