Compounds > tyramine
Page last updated: 2024-08-16

tyramine and phenyl acetate

tyramine has been researched along with phenyl acetate in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199014 (25.00)18.7374
1990's2 (3.57)18.2507
2000's12 (21.43)29.6817
2010's23 (41.07)24.3611
2020's5 (8.93)2.80

Authors

AuthorsStudies
Berde, B; Fanchamps, A1
Gailis, L; Nguyen, MH1
Axelsson, S; Björklund, A; Lindvall, O1
Counsell, RE; Desai, P; Noronha, OP; Ranade, VV; Smith, TD1
Iwakuma, T; Nakai, H; Witkop, B; Yonemitsu, O1
Hirao, K; Iwakuma, T; Yonemitsu, O1
Smith, CB; Steinberg, MI1
Mushahwar, IK; Oliner, L; Schulz, AR1
Creaven, PJ; McIsaac, WM; Tacker, M1
Friedhoff, AJ; Schweitzer, JW; Van Winkle, E1
Tipton, KF1
Garvey, TQ; Goldstein, M; Joh, TH1
Augenstein, L; Bishai, F; Kuntz, E1
Holowka, D1
de Kock, SS; Louw, A; Swart, P; van der Merwe, KJ1
Louw, A; Swart, P1
Ishiwa-Chigusa, S; Komatsu, A; Kutsukake, M; Yamamoto, D1
Allie, F; Louw, A; Swart, P1
Allie, F; Louw, A; Swart, AC; Swart, P1
Eiraku, T; Hirashima, A; Kuwano, E; Shigeta, Y1
Claessens, F; Hapgood, JP; Louw, A; Rombauts, W; Tanner, TM; Verrijdt, G1
Louw, A; Swart, AC; Swart, P; van der Merwe, KJ1
Rehwinkel, H; Schäcke, H1
De Bosscher, K; Deforce, D; Dewint, P; Elewaut, D; Gossye, V; Haegeman, G; Müller-Ladner, U; Van Beneden, K; Van Calenbergh, S; Vanden Berghe, W; Vander Cruyssen, B; Verbruggen, G1
Budunova, I; Chatterton, RT; Czwornog, J; Gera, L; Joshi, S; Yemelyanov, A1
De Bosscher, K; Dewint, P; Elewaut, D; Gossye, V; Haegeman, G; Van Beneden, K1
Schluesener, HJ; Zhang, Z; Zhang, ZY1
Bougarne, N; Bracke, D; De Bosscher, K; Elewaut, D; Gossye, V; Haegeman, G; Van Calenbergh, S1
Beyaert, R; Bougarne, N; De Bosscher, K; Haegeman, G; Mc Guire, C; Praet, J; Prinz, M; Sze, M; Ullrich, A; van Loo, G1
Hanisch, UK; John, M; Lühder, F; Menzfeld, C; Reichardt, HM; Tischner, D; Tuckermann, JP; van den Brandt, J; Wüst, S1
Bornhaeuser, M; De Bosscher, K; Goettsch, C; Haegeman, G; Hofbauer, LC; Rauner, M; Stein, N; Thiele, S; Tuckermann, J1
Budunova, IV; Kirsanov, KI; Lesovaya, EA; Yakubovskaya, MG; Yemelyanov, AY1
Bhalla, P; Budunova, I; Iwadate, K; Karseladze, A; Ugolkov, A; Yang, X; Yemelyanov, A1
Hanausek, M; Junco, JJ; Kinjo, T; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Tolstykh, O; Truong, H; Walaszek, Z1
Daubeuf, F; De Bosscher, K; De Cauwer, L; Frossard, N; Gerlo, S; Haegeman, G; Lambrecht, BN; Plantinga, M; Reber, LL; Tavernier, J; Van Calenbergh, S; Waelput, W1
Antunica-Noguerol, M; Arzt, E; Castro, CN; De Bosscher, K; Druker, J; Ferraz-de-Paula, V; Gerlo, S; Haegeman, G; Holsboer, F; Liberman, AC; Palermo-Neto, J; Perone, MJ1
Hapgood, JP; Louw, A; Robertson, S1
Haegeman, G; Khunchai, S; Limjindaporn, T; Morchang, A; Noisakran, S; Panaampon, J; Puttikhunt, C; Suttitheptumrong, A; Yasamut, U; Yenchitsomanus, PT1
Grounds, MD; Haegeman, G; Harris, M; Heier, CR; Huynh, T; Nagaraju, K; Nolan, CJ; Quinn, JL; Tatem, KS; Uaesoontrachoon, K; Van Der Meulen, JH; Yu, Q1
Gloe, I; Haegeman, G; Hofbauer, LC; Peschke, K; Rauner, M; Salbach-Hirsch, J; Sinningen, K; Thiele, S; Tuckermann, JP; Winzer, M1
Haegeman, G; Nikolic, I; Saksida, T; Stojanovic, I; Stosic-Grujicic, S; Vujicic, M1
Beck, IM; Bracke, M; Drebert, Z1
Bachert, C; Beck, IM; Daubeuf, F; De Bosscher, K; Frossard, N; Holtappels, G; Van Crombruggen, K1
Amrani, Y; Brightling, C; Chachi, L; Gavrila, A; Tliba, O1
Ide, H; Inoue, S; Ishiguro, H; Jalalizadeh, M; Kashiwagi, E; Kawahara, T; Miyamoto, H; Reis, LO; Zheng, Y1
Chen, Z; Clinton, SK; Huang, J; Jin, VX; Lan, X; Liu, Z; Sunkel, B; Wang, Q; Wu, D; Ye, Z1
Haegeman, G; Junking, M; Limjindaporn, T; Panya, A; Rattanaburee, T; Sawasdee, N; Songprakhon, P; Suttitheptumrong, A; Yenchitsomanus, PT1
Andreone, L; Antunica-Noguerol, M; Ariolfo, L; Barcala Tabarrozzi, AE; Berguer, PM; Castro, CN; De Bosscher, K; Deckers, J; Gimeno, ML; Liberman, AC; Perone, MJ; Tuckermann, JP; Vettorazzi, S1
Chantharasamee, J; Ithimakin, S; Singsuksawat, E; Sootichote, R; Thuwajit, C; Thuwajit, P; Warnnissorn, M; Yenchitsomanus, PT1
De Bosscher, K; De Cauwer, L; De Rycke, R; Deckers, J; Gevaert, K; Impens, F; Libert, C; Mylka, V; Ratman, D; Tavernier, J; Thommis, J; Vanden Berghe, W1
Antonicelli, F; Bernard, P; Bini, E; Didier, K; Durlach, A; Gatouillat, G; Giusti, D; Le Jan, S; Muller, C; Nesmond, S; Pham, BN; Terryn, C1
Armando, AM; Chi, NW; Chi, TJ; Evans, RM; Hah, N; Oh, DY; Olefsky, JM; Osborn, O; Paschoal, VA; Pessentheiner, AR; Quehenberger, O; Talukdar, S; Tye, GL; Walenta, E1
Anayama, H; Hanauer, G; Hazama, M; Matsuo, T; Nio, Y; Ookawara, M; Sano, T; Shibata, S; Shimizu, F; Tohyama, K; Yamasaki, M1
Budunova, I; Haegeman, G; Junking, M; Panya, A; Rattanaburee, T; Yenchitsomanus, PT1
Kazazoglou, T; Kokkinopoulou, I; Mihailidou, C; Moutsatsou, P; Panagiotou, C; Papadopoulou, A1
Barnes, S; Cohn, SM; Cong, Y; Dann, SM; Li, Y; Liu, H; Xu, L; Yang, W; Yao, S; Yu, T; Zhang, H; Zhao, Q; Zhao, X; Zuo, X1

Reviews

2 review(s) available for tyramine and phenyl acetate

ArticleYear
[Importance of humoral mediators for the pathogenesis and treatment of migraine (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Sep-19, Volume: 117, Issue:38

    Topics: Acetates; Animals; Blood Vessels; Cerebrovascular Circulation; Diet; Estrogens; Headache; Histamine; Humans; Kinins; Mice; Migraine Disorders; Polymyxins; Prolactin; Prostaglandins; Reserpine; Serotonin; Tyramine; Vascular Headaches

1975
GR ligands: can we improve the established drugs?
    ChemMedChem, 2006, Volume: 1, Issue:8

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Ligands; Mice; Receptors, Glucocorticoid; Tyramine

2006

Other Studies

54 other study(ies) available for tyramine and phenyl acetate

ArticleYear
Effect of acetaldehyde on the isolated, non-working guinea-pig heart: independence of the coronary flow increase from changes in heart rate and oxygen consumption.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3

    Topics: Acetaldehyde; Acetates; Animals; Atropine; Coronary Circulation; Epinephrine; Ethanol; Guinea Pigs; Heart Arrest, Induced; Heart Rate; Hypoxia; In Vitro Techniques; Isoproterenol; Myocardium; Norepinephrine; Oxygen Consumption; Perfusion; Phentolamine; Propranolol; Pyruvates; Reserpine; Theophylline; Tranylcypromine; Tyramine; Vascular Resistance

1974
Fluorescence histochemistry of biogenic monoamines. A study of the capacity of various carbonyl compounds to form fluorophores with biogenic monoamines in gas phase reactions.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1972, Volume: 20, Issue:6

    Topics: Acetates; Aldehydes; Amines; Biogenic Amines; Carboxylic Acids; Catecholamines; Fluorescence; Formaldehyde; Formates; Gases; Glyoxylates; Histamine; Histocytochemistry; Indoles; Keto Acids; Ketones; Melatonin; Octopamine; Pyruvates; Serotonin; Tyramine

1972
Potential organ or tumor imaging agents. 11. Radioiodinated tyramines.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:6

    Topics: Acetates; Adrenal Gland Neoplasms; Adrenal Medulla; Aluminum; Animals; Benzoates; Benzyl Compounds; Boranes; Diazonium Compounds; Dogs; Iodine Isotopes; Iron; Lithium; Methods; Nitro Compounds; Oxidation-Reduction; Phenethylamines; Pheochromocytoma; Sulfuric Acids; Tritium; Tyramine

1973
Photocyclizations of N-chloroacetyltyramine. I. Formation of novel dimeric cage compounds.
    Journal of the American Chemical Society, 1974, Apr-17, Volume: 96, Issue:8

    Topics: Acetates; Azocines; Chlorine; Cyclization; Photochemistry; Tyramine

1974
Photocyclizations of N-chloroacetyltyramines. II. Flash photolysis and substituent effect studies on the formation of dimeric cage compounds, and novel acid-catalyzed reversion.
    Journal of the American Chemical Society, 1974, Apr-17, Volume: 96, Issue:8

    Topics: Acetates; Acids; Azocines; Catalysis; Chlorine; Photochemistry; Photolysis; Tyramine

1974
Effects of desmethylimipramine and cocaine on the uptake, retention and metabolism of H3-tyramine in rat brain slices.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 173, Issue:1

    Topics: Acetates; Animals; Brain; Brain Stem; Caudate Nucleus; Cell Membrane; Cocaine; Desipramine; Female; Hypothalamus; In Vitro Techniques; Kinetics; Male; Mandelic Acids; Norepinephrine; Octopamine; Rats; Tritium; Tyramine

1970
Bovine thyroid microsomal monoamine oxidase.
    Canadian journal of biochemistry, 1972, Volume: 50, Issue:10

    Topics: Acetates; Ammonium Sulfate; Animals; Bromides; Calcium Phosphates; Cattle; Chlorides; Chromatography, DEAE-Cellulose; Detergents; Drug Stability; Feedback; Fluorides; Iodides; Ions; Kinetics; Microsomes; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship; Temperature; Thiocyanates; Thyroid Gland; Tyramine

1972
Alteration in tyramine metabolism by ethanol.
    Biochemical pharmacology, 1970, Volume: 19, Issue:2

    Topics: Acetates; Animals; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Ethanol; Glucuronates; Glycine; Injections, Intraperitoneal; Male; Rats; Tyramine

1970
Beta-hydroxylation of N-acetyl-3,4-dimethoxyphenethylamine and the influence of iproniazid on the demethylation of this compound in vivo in the rat.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Acetamides; Acetates; Alcohols; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Crystallization; Dealkylation; Depression, Chemical; Esters; Iproniazid; Male; Mass Spectrometry; Metabolism; Methylation; Phenethylamines; Phenylacetates; Rats; Tyramine

1970
The purification of pig brain mitochondrial monoamine oxidase.
    European journal of biochemistry, 1968, Volume: 4, Issue:1

    Topics: Acetates; Animals; Brain; Cellulose; Electrophoresis; Hydrogen-Ion Concentration; Kinetics; Methods; Mitochondria; Molecular Weight; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidation-Reduction; Swine; Tyramine; Ultrasonics

1968
Kinetic studies of the enzymatic dopamine beta-hydroxylation reaction.
    Biochemistry, 1968, Volume: 7, Issue:8

    Topics: Acetates; Ascorbic Acid; Chemical Phenomena; Chemistry; Dopamine; Fumarates; Kinetics; Mixed Function Oxygenases; Models, Biological; Oxidation-Reduction; Oxygen; Tyramine

1968
Intra- and intermolecular factors affecting the excited states of aromatic amino acids.
    Biochimica et biophysica acta, 1967, Aug-15, Volume: 140, Issue:3

    Topics: Acetates; Amides; Cinnamates; Energy Transfer; Fluorescence; Hydrochloric Acid; Hydrogen-Ion Concentration; Luminescent Measurements; Phenols; Phenylalanine; Sodium Chloride; Sodium Hydroxide; Spectrophotometry; Tryptophan; Tyramine; Tyrosine

1967
N-chloroacetyl-[125I]iodotyramine: an alkylating agent with high specific activity.
    Analytical biochemistry, 1981, Nov-01, Volume: 117, Issue:2

    Topics: Acetates; Alkylation; Endonucleases; Immunoglobulin E; Iodine Radioisotopes; Iodoacetamide; Iodoacetates; Kinetics; Ribonuclease, Pancreatic; Ribonucleases; Spectrum Analysis; Sulfhydryl Reagents; Tyramine

1981
Mechanism for the stabilization in vivo of the aziridine precursor --(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride by serum proteins.
    Biochemical pharmacology, 1997, Jan-24, Volume: 53, Issue:2

    Topics: Acetates; Animals; Blood Proteins; Contraceptives, Oral; Cytochrome P-450 CYP11B2; Desoxycorticosterone; Drug Stability; Ethylamines; Female; Mass Spectrometry; Rats; Rats, Wistar; Sex Hormone-Binding Globulin; Transcortin; Tyramine

1997
Salsola tuberculatiformis Botschantzev and an aziridine precursor analog mediate the in vivo increase in free corticosterone and decrease in corticosteroid-binding globulin in female Wistar rats.
    Endocrinology, 1999, Volume: 140, Issue:5

    Topics: Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Aziridines; Corticosterone; Enzyme Inhibitors; Ethylamines; Female; Follicle Stimulating Hormone; Liver; Luteinizing Hormone; Organ Size; Ovary; Plants; Rats; Rats, Wistar; Steroid 11-beta-Hydroxylase; Transcortin; Tyramine; Uterus

1999
A tyramine receptor gene mutation causes a defective olfactory behavior in Drosophila melanogaster.
    Gene, 2000, Mar-07, Volume: 245, Issue:1

    Topics: Acetates; Animals; Behavior, Animal; Benzaldehydes; Central Nervous System; Cyclohexanols; DNA Transposable Elements; Dose-Response Relationship, Drug; Drosophila melanogaster; Electrophysiology; Enhancer Elements, Genetic; Exons; Gene Expression Regulation, Developmental; Genes; Introns; Larva; Muscles; Mutagenesis, Insertional; Mutation; Octopamine; Olfactory Pathways; Receptors, Biogenic Amine; Tyramine

2000
Influence of an aziridine precursor on the in vitro binding parameters of rat and ovine corticosteroid-binding globulin (CBG).
    Biochemical pharmacology, 2000, Jan-15, Volume: 59, Issue:2

    Topics: Acetates; Animals; Aziridines; Binding, Competitive; Contraceptives, Oral; Ethylamines; Female; Glucocorticoids; Ligands; Progesterone; Rats; Rats, Wistar; Sheep; Tissue Distribution; Transcortin; Tyramine

2000
Inhibition of cytochrome P450c11 by biogenic amines and an aziridine precursor, 2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride.
    Endocrine research, 2000, Volume: 26, Issue:4

    Topics: Acetates; Animals; Biogenic Monoamines; Cell Line; Corticosterone; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Ethylamines; Humans; Mixed Function Oxygenases; Sheep; Steroid 11-beta-Hydroxylase; Tyramine

2000
Three-dimensional pharmacophore hypotheses of octopamine/tyramine agonists which inhibit [1-14C]acetate incorporation in Plodia interpunctella.
    Bioorganic & medicinal chemistry, 2003, Jan-02, Volume: 11, Issue:1

    Topics: Acetates; Animals; Carbon Radioisotopes; Drug Design; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Structure; Moths; Octopamine; Quantitative Structure-Activity Relationship; Sex Attractants; Structure-Activity Relationship; Tyramine

2003
Anti-androgenic properties of Compound A, an analog of a non-steroidal plant compound.
    Molecular and cellular endocrinology, 2003, Mar-28, Volume: 201, Issue:1-2

    Topics: Acetates; Androgen Antagonists; Androgens; Animals; Binding Sites; Cells, Cultured; DNA; Ethylamines; Gene Expression Regulation; Genes, Reporter; Haplorhini; Histone Acetyltransferases; Humans; Ligands; Male; Nuclear Receptor Coactivator 1; Plants; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Structure, Tertiary; Receptors, Androgen; Transcription Factors; Transcription, Genetic; Transfection; Tyramine

2003
Biological activities of the shrub Salsola tuberculatiformis Botsch.: contraceptive or stress alleviator?
    BioEssays : news and reviews in molecular, cellular and developmental biology, 2003, Volume: 25, Issue:6

    Topics: Acetates; Animals; Biological Products; Caryophyllaceae; Contraceptive Agents; Cytochrome P-450 Enzyme System; Ethylamines; Female; Models, Biological; Models, Chemical; Oxidative Stress; Plant Extracts; Plant Proteins; Protein Conformation; Rats; Steroid 11-beta-Hydroxylase; Steroids; Tyramine

2003
A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Feb-15, Volume: 180, Issue:4

    Topics: Acetates; Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Line; Collagen Type II; Dexamethasone; Dimerization; Ethylamines; Humans; Ligands; Male; Mice; Mice, Inbred DBA; Plant Extracts; Protein Conformation; Receptors, Glucocorticoid; Response Elements; Salsola; Synovial Membrane; Trans-Activators; Tyramine

2008
Novel steroid receptor phyto-modulator compound a inhibits growth and survival of prostate cancer cells.
    Cancer research, 2008, Jun-15, Volume: 68, Issue:12

    Topics: Acetates; Androgen Antagonists; Androgens; Apoptosis; Blotting, Western; Cell Proliferation; Colony-Forming Units Assay; Electrophoretic Mobility Shift Assay; Ethylamines; Humans; Hydrogen Bonding; Luciferases; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Radioligand Assay; Receptors, Androgen; Receptors, Glucocorticoid; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tyramine

2008
A plant-derived glucocorticoid receptor modulator attenuates inflammation without provoking ligand-induced resistance.
    Annals of the rheumatic diseases, 2010, Volume: 69, Issue:1

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Dexamethasone; Down-Regulation; Drug Evaluation, Preclinical; Drug Resistance; Ethylamines; Glucocorticoids; Inflammation Mediators; Ligands; Male; Mice; Mice, Inbred DBA; Receptors, Glucocorticoid; Tyramine

2010
Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects.
    Journal of immunology (Baltimore, Md. : 1950), 2009, Sep-01, Volume: 183, Issue:5

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Cell Proliferation; Disease Progression; Down-Regulation; Ethylamines; Macrophages; Male; Mice; Neuritis, Autoimmune, Experimental; Rats; Receptors, Glucocorticoid; Salsola; T-Lymphocytes, Regulatory; Tyramine; Up-Regulation

2009
Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:11

    Topics: Acetates; Arthritis, Rheumatoid; Cells, Cultured; Dexamethasone; eIF-2 Kinase; Fibroblasts; Glucocorticoids; Humans; I-kappa B Kinase; Interleukin-1beta; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Quaternary Ammonium Compounds; Receptors, Glucocorticoid; RNA, Small Interfering; Synovial Membrane; Tyramine

2009
Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis.
    Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:2

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cells, Cultured; Cytokines; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Neuroprotective Agents; NF-kappa B; Protein Transport; Quaternary Ammonium Compounds; Receptors, Glucocorticoid; RNA, Messenger; Spinal Cord; T-Lymphocytes; Time Factors; Tyramine

2010
Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis.
    PloS one, 2009, Dec-07, Volume: 4, Issue:12

    Topics: Acetates; Animals; Apoptosis; Aziridines; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Encephalomyelitis, Autoimmune, Experimental; Fibroblasts; Guinea Pigs; Interleukin-17; Ligands; Mice; Mice, Inbred C57BL; Mitochondria; Multiple Sclerosis; Myelin Sheath; Organ Specificity; Quaternary Ammonium Compounds; Receptors, Glucocorticoid; Solvents; Synephrine; T-Lymphocytes; Transcriptional Activation; Tyramine

2009
Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells.
    Endocrinology, 2011, Volume: 152, Issue:1

    Topics: Acetates; Adult; Apoptosis; Bone Marrow Cells; Cells, Cultured; Coculture Techniques; Ethylamines; Female; Humans; Interleukin-1; Interleukin-6; Male; Middle Aged; Monocytes; Osteoclasts; Osteogenesis; Receptors, Glucocorticoid; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyramine; Young Adult

2011
Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562.
    Biochemistry. Biokhimiia, 2011, Volume: 76, Issue:11

    Topics: Acetates; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cytostatic Agents; Fluocinolone Acetonide; Humans; K562 Cells; Leukemia; Ligands; NF-kappa B; Pyrazines; Receptors, Glucocorticoid; Tacrolimus Binding Proteins; Transcription Factor AP-1; Tyramine

2011
Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: a novel therapeutic modality.
    Cell cycle (Georgetown, Tex.), 2012, Jan-15, Volume: 11, Issue:2

    Topics: Acetates; Adult; Aged; Aged, 80 and over; Androgen Receptor Antagonists; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Carcinoma; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; Pyrazines; Receptors, Androgen; Receptors, Glucocorticoid; Transcription Factor CHOP; Transcriptional Activation; Tyramine

2012
The possible separation of 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation and hyperplasia by compound A.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:6

    Topics: Acetates; Animals; Cyclooxygenase 2; Cytokines; Drug Eruptions; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred SENCAR; NF-kappa B; Proto-Oncogene Proteins c-jun; Receptors, Glucocorticoid; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tyramine

2013
A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Apr-01, Volume: 188, Issue:7

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Dual Specificity Phosphatase 1; Enzyme Induction; Gene Expression Regulation; Goblet Cells; Inflammation; Leukocytes; Lung; Mast Cells; Metaplasia; Mice; Mice, Inbred BALB C; Ovalbumin; Quaternary Ammonium Compounds; Receptors, Glucocorticoid; STAT6 Transcription Factor; Transcriptional Activation; Tyramine

2012
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Acetates; Animals; Aziridines; GATA3 Transcription Factor; Interferon-gamma; Mice; Mice, Inbred BALB C; Mifepristone; Quaternary Ammonium Compounds; Receptors, Glucocorticoid; Spleen; T-Box Domain Proteins; T-Lymphocytes; Th1 Cells; Th1-Th2 Balance; Th2 Cells; Tyramine

2012
Glucocorticoid receptor concentration and the ability to dimerize influence nuclear translocation and distribution.
    Steroids, 2013, Volume: 78, Issue:2

    Topics: Acetates; Active Transport, Cell Nucleus; Animals; Cell Nucleus; Cell Survival; Chlorocebus aethiops; COS Cells; Dexamethasone; Fluorescent Antibody Technique; Green Fluorescent Proteins; Humans; Models, Biological; Protein Binding; Protein Multimerization; Receptors, Glucocorticoid; Tyramine

2013
Compound A, a dissociated glucocorticoid receptor modulator, reduces dengue virus-induced cytokine secretion and dengue virus production.
    Biochemical and biophysical research communications, 2013, Jun-28, Volume: 436, Issue:2

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Migration Assays, Leukocyte; Chemokine CXCL10; Chemotaxis; Chlorocebus aethiops; Cytokines; Dengue Virus; Flow Cytometry; Gene Expression; Hep G2 Cells; Host-Pathogen Interactions; Humans; Liver Neoplasms; Plant Extracts; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Salsola; Tumor Necrosis Factor-alpha; Tyramine

2013
Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice.
    The Journal of pathology, 2013, Volume: 231, Issue:2

    Topics: Acetates; Animals; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Male; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-kappa B; Real-Time Polymerase Chain Reaction; Receptors, Glucocorticoid; Tyramine

2013
Effects of the selective glucocorticoid receptor modulator compound A on bone metabolism and inflammation in male mice with collagen-induced arthritis.
    Endocrinology, 2013, Volume: 154, Issue:10

    Topics: Acetates; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; Joints; Lymphocyte Activation; Male; Mice; Mice, Inbred DBA; Osteoclasts; Osteogenesis; Random Allocation; Receptors, Glucocorticoid; T-Lymphocytes; Tyramine

2013
Compound A, a selective glucocorticoid receptor agonist, inhibits immunoinflammatory diabetes, induced by multiple low doses of streptozotocin in mice.
    British journal of pharmacology, 2014, Volume: 171, Issue:24

    Topics: Acetates; Animals; Antibiotics, Antineoplastic; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Insulin; Insulin-Secreting Cells; Macrophages; Mice; Receptors, Glucocorticoid; Streptozocin; Th1 Cells; Th17 Cells; Tyramine

2014
Glucocorticoids and the non-steroidal selective glucocorticoid receptor modulator, compound A, differentially affect colon cancer-derived myofibroblasts.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 149

    Topics: Acetates; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Humans; Myofibroblasts; NF-kappa B; Receptors, Glucocorticoid; Transcriptional Activation; Tyramine

2015
Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Acetates; Adolescent; Adult; Anti-Inflammatory Agents; Cell Survival; Cytokines; Female; Glucocorticoids; Humans; Inflammation Mediators; Leukocytes, Mononuclear; Male; Methylprednisolone; Middle Aged; Mifepristone; Receptors, Glucocorticoid; Th1 Cells; Th2 Cells; Tyramine; Young Adult

2015
Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells.
    American journal of respiratory cell and molecular biology, 2015, Volume: 53, Issue:5

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Case-Control Studies; Chemokine CCL5; Chemokine CX3CL1; Chemokine CXCL10; Drug Resistance; Dual Specificity Phosphatase 1; Epithelial Cells; Female; Fluticasone; Gene Expression; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Male; Middle Aged; Mifepristone; Primary Cell Culture; Receptors, Glucocorticoid; Respiratory Mucosa; RNA, Small Interfering; Tumor Necrosis Factor-alpha; Tyramine

2015
Compound A Inhibits Bladder Cancer Growth Predominantly via Glucocorticoid Receptor Transrepression.
    Molecular endocrinology (Baltimore, Md.), 2015, Volume: 29, Issue:10

    Topics: Acetates; Androgen Antagonists; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; NF-kappa B; Protein Binding; Receptors, Glucocorticoid; Repressor Proteins; Transcriptional Activation; Tyramine; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2015
Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer.
    Nature communications, 2015, Sep-16, Volume: 6

    Topics: Acetates; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Dexamethasone; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Glucocorticoids; Humans; Ligands; Paclitaxel; Receptors, Glucocorticoid; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Triple Negative Breast Neoplasms; Tyramine

2015
Inhibition of dengue virus production and cytokine/chemokine expression by ribavirin and compound A.
    Antiviral research, 2015, Volume: 124

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Antiviral Agents; Cell Line, Tumor; Chemokines; Cytokines; Dengue; Dengue Virus; Drug Synergism; Humans; Ribavirin; Tyramine; Vero Cells; Virus Replication

2015
GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.
    Scientific reports, 2016, 11-18, Volume: 6

    Topics: Acetates; Animals; B7-1 Antigen; Bone Marrow Cells; Dendritic Cells; Down-Regulation; Endocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Inflammation Mediators; Lipopolysaccharides; Mice; Receptors, Glucocorticoid; Toll-Like Receptor 4; Tyramine; Up-Regulation

2016
Compound A attenuates toll-like receptor 4-mediated paclitaxel resistance in breast cancer and melanoma through suppression of IL-8.
    BMC cancer, 2018, 02-27, Volume: 18, Issue:1

    Topics: Acetates; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Interleukin-6; Interleukin-8; Melanoma; Paclitaxel; Signal Transduction; Toll-Like Receptor 4; Tumor Microenvironment; Tyramine

2018
The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages.
    Autophagy, 2018, Volume: 14, Issue:12

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Cells, Cultured; Dexamethasone; Gene Expression Regulation; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Receptors, Glucocorticoid; Sequestosome-1 Protein; Transcriptional Activation; Tyramine

2018
NET Formation in Bullous Pemphigoid Patients With Relapse Is Modulated by IL-17 and IL-23 Interplay.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Acetates; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Eosinophils; Extracellular Traps; Female; Humans; Interleukin-17; Interleukin-23 Subunit p19; Male; Methylprednisolone; Middle Aged; Neutrophils; Pemphigoid, Bullous; Prospective Studies; Recurrence; Translational Research, Biomedical; Tyramine

2019
Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity.
    Cell metabolism, 2020, 06-02, Volume: 31, Issue:6

    Topics: 3T3-L1 Cells; Acetates; Adipocytes; Animals; Cells, Cultured; Female; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; PPAR gamma; Receptors, G-Protein-Coupled; Rosiglitazone; Tyramine

2020
Ameliorative effect of phosphodiesterase 4 and 5 inhibitors in deoxycorticosterone acetate-salt hypertensive uni-nephrectomized KKA
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:11

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiomegaly; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Desoxycorticosterone; Female; Hyperglycemia; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoids; Phosphodiesterase 5 Inhibitors; Renal Insufficiency; Sildenafil Citrate; Sodium Chloride; Tyramine

2020
Anti-Proliferative Effects of Compound A and Its Effect in Combination with Cisplatin in Cholangiocarcinoma Cells.
    Asian Pacific journal of cancer prevention : APJCP, 2020, 09-01, Volume: 21, Issue:9

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Bile Duct Neoplasms; Cell Cycle; Cell Proliferation; Cholangiocarcinoma; Cisplatin; Drug Therapy, Combination; Humans; Leukocytes, Mononuclear; Tumor Cells, Cultured; Tyramine

2020
Glutamine synthetase regulation by dexamethasone, RU486, and compound A in astrocytes derived from aged mouse cerebral hemispheres is mediated via glucocorticoid receptor.
    Molecular and cellular biochemistry, 2021, Volume: 476, Issue:12

    Topics: Acetates; Age Factors; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cells, Cultured; Cerebrum; Dexamethasone; Glutamate-Ammonia Ligase; Hormone Antagonists; Mice; Mifepristone; Receptors, Glucocorticoid; Tyramine

2021
GPR120 Inhibits Colitis Through Regulation of CD4
    Gastroenterology, 2022, Volume: 162, Issue:1

    Topics: Acetates; Adoptive Transfer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; CD4-Positive T-Lymphocytes; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Disease Models, Animal; Glycolysis; Interleukin-10; Mice, Inbred C57BL; Mice, Knockout; Receptors, G-Protein-Coupled; Signal Transduction; Tyramine

2022