Page last updated: 2024-08-26

tylophorine and antofine

tylophorine has been researched along with antofine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Chen, AP; Cheng, YC; Fürstner, A; Gao, W; Gullen, EA; Lee, KH; Leung, CH; Shi, Q; Wei, L1
Chen, F; Han, G; Li, Z; Liu, Y; Meng, L; Wang, K; Wang, L; Wang, Q; Wang, Y; Wang, Z; Wu, M; Zhang, A1
Wang, L; Wang, Q; Wang, Z; Wei, P1
Fürstner, A; Kennedy, JW1
Bastow, KF; Lee, KH; Lin, JC; Liu, YN; Shi, Q; Yang, PC; Yang, SC; Yang, X; Zhao, G1
Liu, Y; Park, CM; Xu, X1
Liu, Y; Wang, Q; Zheng, Y1
Liu, GQ; Opatz, T; Reimann, M1
Abdalla, AN; Abdullah, O; Chen, L; Fischer, PM; Guise, CP; Liu, Y; Omran, Z; Patterson, AV; Rauch, C; Sindi, IA; Smaill, JB; Wang, Q1

Other Studies

9 other study(ies) available for tylophorine and antofine

ArticleYear
Structural analogs of tylophora alkaloids may not be functional analogs.
    Bioorganic & medicinal chemistry letters, 2008, Jan-15, Volume: 18, Issue:2

    Topics: Alkaloids; Cell Line; Humans; Signal Transduction; Structure-Activity Relationship; Tylophora

2008
Synthesis and SAR studies of phenanthroindolizidine and phenanthroquinolizidine alkaloids as potent anti-tumor agents.
    European journal of medicinal chemistry, 2012, Volume: 51

    Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Indolizines; Phenanthrolines; Quinolizines; Structure-Activity Relationship

2012
Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of phenanthroindolizidines and their analogues.
    Journal of agricultural and food chemistry, 2012, Oct-17, Volume: 60, Issue:41

    Topics: Antiviral Agents; Drug Design; Indolizidines; Indolizines; Phenanthrolines; Plant Diseases; RNA, Viral; Tobacco Mosaic Virus

2012
Total syntheses of the tylophora alkaloids cryptopleurine, (-)-antofine, (-)-tylophorine, and (-)-ficuseptine C.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2006, Sep-25, Volume: 12, Issue:28

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Indoles; Indolizines; Phenanthrenes; Phenanthrolines

2006
Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.
    Journal of medicinal chemistry, 2009, Aug-27, Volume: 52, Issue:16

    Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Indolizines; Models, Molecular; Molecular Conformation; NF-kappa B; Phenanthrenes; Phenanthrolines; Piperidines; Proto-Oncogene Proteins c-akt; Signal Transduction; Stereoisomerism; Structure-Activity Relationship

2009
Rhodium(III)-catalyzed intramolecular annulation through C-H activation: total synthesis of (±)-antofine, (±)-septicine, (±)-tylophorine, and rosettacin.
    Angewandte Chemie (International ed. in English), 2012, Sep-10, Volume: 51, Issue:37

    Topics: Alkaloids; Alkynes; Carbon; Catalysis; Cyclization; Heterocyclic Compounds, 4 or More Rings; Hydrogen; Indoles; Indolizines; Isoquinolines; Phenanthrenes; Phenanthrolines; Pyridones; Rhodium; Stereoisomerism

2012
Collective asymmetric synthesis of (-)-antofine, (-)-cryptopleurine, (-)-tylophorine, and (-)-tylocrebrine with tert-butanesulfinamide as a chiral auxiliary.
    The Journal of organic chemistry, 2014, Apr-18, Volume: 79, Issue:8

    Topics: Alkaloids; Butanes; Indoles; Indolizines; Isomerism; Molecular Structure; Phenanthrenes; Phenanthrolines; Stereoisomerism; Sulfonamides

2014
Total Synthesis of Phenanthroindolizidine Alkaloids by Combining Iodoaminocyclization with Free Radical Cyclization.
    The Journal of organic chemistry, 2016, 07-15, Volume: 81, Issue:14

    Topics: Alkaloids; Chemistry, Organic; Cyclization; Free Radicals; Indoles; Indolizines; Isoquinolines; Magnetic Resonance Spectroscopy; Phenanthrenes; Phenanthrolines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Temperature

2016
Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents.
    Molecules (Basel, Switzerland), 2021, Jun-01, Volume: 26, Issue:11

    Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; CHO Cells; Cricetulus; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Indoles; Indolizines; MCF-7 Cells; Molecular Structure; Phenanthrenes; Phenanthrolines; Prodrugs; Quaternary Ammonium Compounds; Structure-Activity Relationship; Tumor Hypoxia

2021